Tue, 31 May 2022 14:07:02 BST
Research by Institute of Infection, Immunity and Inflammation scientists, led by Dr Katja Thümmler, has shown for the first time that iron overload can actively contribute to the ongoing brain damage in progressive multiple sclerosis (PMS), confirming that treatments designed to prevent this iron-related injury could slow accumulation of disability in PMS patients.
Tue, 10 May 2022 13:28:00 BST
Research led by the Institute of Infection, Immunity and Inflammation's Professor Markus Meißner has discovered a new method that blocks the protein regulation of the parasite Toxoplasma gondii and causes it to die off inside the host cell.
Thu, 31 Mar 2022 15:50:00 BST
Institute Director Professor Andy Waters and Dean of Global Engagement (Middle East/Africa) Professor Paul Garside recently visited Zambia to establish collaborations and partnerships with institutions in the south-central African nation.
Thu, 10 Mar 2022 11:36:07 GMT
Institute scientists have used a combination of novel cell tracking approaches and murine models of inflammatory arthritis to identify genes, pathways and anatomically-specific tissue signatures regulating cell migration in a variety of inflamed sites to provide an invaluable resource for the identification of novel therapeutic targets for arthritis and other inflammatory disorders.
Thu, 03 Mar 2022 12:35:41 GMT
Institute researchers have examined the potential of human mesenchymal stromal cells (MSC) to ameliorate disease in a mouse model of Multiple Sclerosis (known as experimental autoimmune encephalomyelitis or EAE).
Thu, 24 Feb 2022 10:59:36 GMT
Research led by Centre for Virus Research and University of Oxford scientists, in collaboration with UKHSA and Brighton NHS, has revealed new insights into transmissibility of SARS-CoV-2 variants and susceptibility to infection.
Tue, 22 Feb 2022 12:55:56 GMT
Researchers at the Centre for Virus Research (CVR) have received £200,000 funding from the Medical Research Council (MRC), matched with more than £100,000 of in-kind funding from MRC Units, to develop the Influenza Virus Toolkit, a reagent repository for influenza virus researchers.
Wed, 08 Dec 2021 12:47:13 GMT
Vaccines are effective in decreasing hospitalisation and deaths from COVID-19 infection but the emergence of viral variants of concern may diminish their efficacy, according to a new study by Centre for Virus Research scientists.
Thu, 25 Nov 2021 09:50:35 GMT
RACE, an iii-led national centre for research into inflammatory arthritis, is proud to announce that all four of its partner University Rheumatology units – in Birmingham, Glasgow, Newcastle and Oxford – have been awarded five year EULAR Centre of Excellence status until either 2025 or 2026.
Wed, 10 Nov 2021 13:26:00 GMT
High levels of anxiety and depression among medical doctors have been recorded in a new cross-country study involving the Institute's Dr Antonia Ho that finds Italian doctors most likely to have experienced mental health symptoms during the Covid-19 pandemic.
Fri, 05 Nov 2021 14:46:22 GMT
The Institute's Alex Mackay was invited to attend a special Malawi Girl Child Partnership reception with Madame Monica Chakwera, the First Lady of Malawi, at the David Livingstone Birthplace Centre, Blantyre as part of COP26 on Monday 1 November 2021.
Mon, 04 Oct 2021 12:03:00 BST
Centre for Virus Research scientists have developed a new machine learning method that can accurately predict which animal viruses could go on to infect humans in the future, using only information encoded in the viral genome.
Thu, 26 Aug 2021 11:45:00 BST
Initial data from the ongoing OCTAVE trial led by Institute scientists shows that a significant proportion of clinically at-risk patients with certain immunocompromised conditions or immunosuppressed therapies mount a lower or undetectable immune response after two doses of the same COVID-19 vaccine.
Fri, 20 Aug 2021 12:41:13 BST
Fri, 20 Aug 2021 12:10:00 BST
The available evidence suggests that animal-to-human transmission associated with infected live animals is the most likely cause of the COVID-19 pandemic, according to a Science Perspective article by the CVR's Professor David Robertson and Spyros Lytras.
Wed, 04 Aug 2021 11:44:24 BST
Researchers at the Institute of Infection, Immunity and Inflammation will play a key role in HIPPOCRATES, the major new EU research project that will promote the early identification of and improve outcomes for patients with psoriatic arthritis.
Thu, 22 Jul 2021 11:40:00 BST
A new study co-authored by the Institute's Dr Antonia Ho and published in The Lancet, is the first to systematically assess a range of in-hospital complications, and their associations with age, sex and ethnicity, and their outcomes for the patients.
Fri, 09 Jul 2021 09:58:00 BST
Research led by RACE's Dr Mariola Kurowska-Stolarska in collaboration with Professor Elisa Gremese, of the Fondazione A.Gemelli IRCCS in Italy, has found that severe COVID-19 and Rheumatoid Arthritis (RA) share disease mechanisms.
Mon, 24 May 2021 15:50:00 BST
New research by the Centre for Virus Research's Kohl Lab shows that the Zika virus capsid interacts with several mosquito protein pathways, revealing pro-viral host factors critical for establishing infection in mosquito cells.
Mon, 17 May 2021 13:08:00 BST
A review article by Institute scientists has concluded that chemokine profiling can be used to predict the in vivo therapeutic potential of mesenchymal stromal cells (MSCs) for diseases such as arthritis, diabetes, transplantation, and Alzheimer’s.
Mon, 10 May 2021 16:11:00 BST
A new paper led by University of Glasgow scientists, including the Institute's Professor Mike Barrett, has brought together the disparate strands of information that currently exist to create the most comprehensive overview of the problem of African Animal Trypanosomiasis yet collated in the twenty-first century.
Mon, 12 Apr 2021 15:27:00 BST
Dr Pasquale Maffia, Dr Mariola Kurowska-Stolarska and Professor Tomasz Guzik (ICAMS) were recently awarded a project grant from the British Heart Foundation (BHF) that will allow the team to continue their research into Axl in atherosclerosis.
Mon, 29 Mar 2021 15:26:00 BST
Research involving Centre for Virus Research scientists has provided new insights into the mosquito factors hijacked by viruses to efficiently establish infection in the mammalian host and may explain how mosquito-borne viruses are so efficiently spread by Aedes mosquitoes.
Wed, 17 Mar 2021 16:28:00 GMT
Institute scientists have found that since December 2019 – and for the first 11 months of the SARS-CoV-2 pandemic – there has been very little ‘important’ genetic change observed in the hundreds of thousands of sequenced virus genomes.
Thu, 11 Mar 2021 11:38:34 GMT
Institute Research Associate Dr Julie Worrell was recently selected to present her work on the long-term consequences of influenza virus infection on cellular communication in the lung at the British Thoracic Society (BTS) Winter meeting.
Thu, 11 Mar 2021 11:09:00 GMT
Institute staff members Mrs Susan Baillie, Professor Sue Barnett, Dr Robert Davies, Mrs Elizabeth McMonagle, and Professor Hugh Willison all recently celebrated 30 years’ service and received a reward from Principal Professor Sir Anton Muscatelli.
Mon, 01 Mar 2021 12:00:35 GMT
An international consortium involving Centre for Virus Research scientists has devised a Coronavirus Toolkit that provides researchers across the world open access to materials, which can be easily and immediately ordered via an online portal, to further research into COVID-19.
Thu, 18 Feb 2021 09:22:42 GMT
A promising treatment for lung disease in cystic fibrosis patients developed by Institute scientists will see scaled up production thanks to support from CPI, a technology innovation centre and member of the UK Government’s High Value Manufacturing Catapult.
Mon, 08 Feb 2021 15:10:00 GMT
The types and combinations of different antibodies in the blood of rheumatoid arthritis sufferers can significantly alter the likelihood of joint damage and progression in the first year of disease, according to a RACE-supported study.
Sun, 31 Jan 2021 23:41:00 GMT
An international collaboration involving Centre for Virus Research scientists Professor David Robertson, Professor Emma Thomson and Dr Ana Filipe has characterised the first significant SARS-CoV-2 mutation, N439K, occurring within the virus’s spike protein receptor binding motif (RBM).
Mon, 25 Jan 2021 16:18:00 GMT
Research by Institute scientists has established the rodent model of malaria, P. berghei, as a useful tool to study the impact and biology of human parasite mutations on the outcome of infection and evolution of drug resistance.
Fri, 15 Jan 2021 16:34:39 GMT
The Institute's Centre for Virus Research is joining a new national research project to study the effects of emerging mutations in SARS-CoV-2, which will be launched with £2.5 million of funding from UK Research and Innovation (UKRI).
Fri, 08 Jan 2021 15:26:00 GMT
Institute CVR scientists sequencing virus samples from both the first confirmed cases of COVID-19 in Scotland and through the first wave have found evidence of community transmission, driven by multiple introductions through international travel, as early as February 2020.
Thu, 07 Jan 2021 16:30:08 GMT
Institute of Infection, Immunity and Inflammation scientists have solved a key parasitic puzzle, revealing the unique and complex structures toxoplasmosis and malaria parasites make in order to survive in different hosts.
Wed, 06 Jan 2021 12:36:55 GMT
The Institute's Professor Paul Garside has won a prestigious Scottish Funding Council Global Challenges Research Fund award to install a groundbreaking solar energy system at the Blantyre Blantyre Research Facility at the University of Malawi.
Thu, 10 Dec 2020 11:39:00 GMT
A study involving the Institute's Dr Thomas Otto has provided proof of concept for methods that classify uncomplicated malaria and severe malaria from non-malarial infections, showing that the machine learning approach is a feasible tool for clinical decision support.
In situ structure of virus capsids within cell nuclei by correlative light and cryo-electron tomography
Fri, 20 Nov 2020 15:37:00 GMT
Tue, 17 Nov 2020 15:54:00 GMT
A new study involving Centre for Virus Research scientists has found cross-species disease progression is accelerated, which reduced the chances of onwards transmission, when the original and new hosts were physiologically or genetically dissimilar.
Mon, 16 Nov 2020 17:11:00 GMT
Dr Daniel Streicker has received a prestigious biological sciences award to integrate data across published biomedical, ecological and virological research studies to answer new and important questions about emerging viruses.
Mon, 16 Nov 2020 11:46:00 GMT
Institute scientists have identified a type of antibody found in multiple sclerosis patients that protects the brain from viruses and their research could aid risk stratification for the therapies that are associated with progressive multifocal leukoencephalopathy. Exploring this novel antiviral mechanism further could also provide a new treatment strategy for viral brain infections.
Tue, 13 Oct 2020 14:39:58 BST
The Institute of Infection, Immunity and Inflammation is delighted to announce that Professor Gerry Graham has been appointed as the Interim Director of the Institute while we seek a new permanent Director, with Professor Paul Garside appointed Interim Deputy.
Mon, 12 Oct 2020 18:22:00 BST
Centre for Virus Research pair Professor Emma Thomson and Dr Sarah McDonald have both been awarded an Officer of the Most Excellent Order of the British Empire (OBE) in recognition of their services to the NHS during the current COVID-19 pandemic.
Mon, 12 Oct 2020 13:52:00 BST
New research by Institute of Infection, Immunity and Inflammation scientists has determined the main mechanism by which H. polygyrus is capable of suppressing a model of Multiple Sclerosis (MS), with the findings building on previous work in the field indicating that Th2-biasing could be a potential therapeutic strategy for autoimmune diseases.
Mon, 05 Oct 2020 11:46:00 BST
A new review involving the Institute's Professor Kevin Maloy has suggested approaches that could be used to better understand how class II major histocompatibility complex molecule expression by Intestinal Epithelial Cells can boost different types of CD4 T cell responses in the gut, which could ultimately lead to better vaccines against intestinal infections.
Thu, 24 Sep 2020 15:49:00 BST
New research by Institute scientists has provided a better understanding of how the parasites causing leishmaniasis replicate their genome prior to cell division - a discovery that could ultimately lead to a better quality of life for sufferers.
Thu, 17 Sep 2020 11:11:00 BST
A project developed by Institute researcher Dr Andreas Haag has produced the first ever complete reconstruction of the two-component signal transduction network of the major human pathogen Staphylococcus aureus.
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei
Mon, 14 Sep 2020 11:58:00 BST
Research by the Institute's Professor Harry De Koning Group has uncovered a new drug resistance mechanism, involving mutations in an aquaporin, by the parasite Trypanosoma brucei, which causes African sleeping sickness.
Thu, 10 Sep 2020 11:11:00 BST
Individuals who are admitted to hospital with COVID-19 can be divided into four distinct groups, according to data from research by the ISARIC Coronavirus Clinical Characterisation Consortium, which involves scientists from our Centre for Virus Research.
Mon, 07 Sep 2020 12:11:00 BST
A new study by Institute of Infection, Immunity and Inflammation scientists has revealed an important insight into how dietary components can change the behaviour of bacteria that cause infections in humans.
Mon, 31 Aug 2020 11:07:07 BST
As members of UK-CIC, Centre for Virus Research scientists will help in the aim to answer key questions on how the immune system interacts with SARS-CoV-2 to help us fight COVID-19 and develop better diagnostics, treatments, and vaccines.
Thu, 27 Aug 2020 12:23:37 BST
Researchers at the Institute's CVR and the University of St Andrews have conducted a systematic review of published and pre-print studies that have investigated the dynamics and length of virus shedding in SARS-CoV-2, as well as similar coronaviruses that caused Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS).
Wed, 12 Aug 2020 14:18:00 BST
The Institute's Dr Chris Moxon (Wellcome Centre for Integrative Parasitology), Dr Thomas Otto, and an international team of collaborators have been awarded a grant from the Bill & Melinda Gates Foundation to conduct a detailed investigation of the changes to tissues and immune system response in fatal COVID-19 cases in Malawi.
Fri, 31 Jul 2020 12:16:46 BST
The UK must prepare now for a potential new wave of coronavirus infections this winter that could be more serious than the first, says a new Academy of Medical Sciences report that included expert input from iii scientists.
Thu, 30 Jul 2020 12:21:00 BST
The Centre for Virus Research's Professor David Robertson has contributed towards research that has discovered the lineage that gave rise to the virus has been circulating in bats for decades and likely includes other viruses with the ability to infect humans.
Mon, 06 Jul 2020 13:26:16 BST
A study involving the Institute's Professor Andrew Roe has found a common protein, carried by most strains of E. coli, controls different sets of genes and discovered that, in the case of the infamous 'burger bug', EHEC, it is a central cause of disease.
Wed, 01 Jul 2020 12:29:00 BST
A study led by the Institute in collaboration with Fondazione A.Gemelli IRCCS in Italy and RACE has, in the joints of individuals on long-term remission, found the key to swift treatments to cure the pain caused by the condition.
Fri, 26 Jun 2020 13:03:00 BST
Through investigating the causes of brain swelling caused by the devastating parasitic disease that is fatal for one in five children, scientists have found an approach that could be safely used to improve outcome.
Thu, 25 Jun 2020 12:12:00 BST
Research involving an Institute scientist has shown that Ethnic Minority patients who are hospitalised with the virus responsible for the current pandemic are more likely to be admitted to critical care and receive mechanical ventilation than White patients.
Wed, 24 Jun 2020 12:37:20 BST
An ongoing collaboration between the Institute, the College of Medical, Veterinary, and Life Sciences (MVLS), the Wellcome Centre For Integrative Parasitology (WCIP), and the Beit Trust has presented a life-changing opportunity to three new African students.
Fri, 19 Jun 2020 13:53:00 BST
Research involving iii's Professor Andrew Roe has provided a mechanistic understanding of the regulation mechanisms of Aldehyde-alcohol dehydrogenase activity via structural transition, and a platform to modulate its activity for developing antibiotics and facilitating biofuel production.
Wed, 17 Jun 2020 11:40:00 BST
Institute scientists are among University of Glasgow researchers that have been awarded funding totalling £710,330 from the GCRF to undertake short-term research projects to urgently assist institutions in Malawi, Uganda, Tanzania, and Colombia.
Fri, 12 Jun 2020 12:25:00 BST
Dr Richard Goodwin, an Imaging Scientist with long-standing links to the Institute and Glasgow Polyomics, has been recognised for his outstanding achievements in the fields of imaging, omics and data integration and a commitment to fostering excellence in research.
Mon, 01 Jun 2020 11:10:00 BST
Institute of Infection, Immunity & Inflammation Centre for Virus Research scientists have discovered a new transmission-blocking microbe in wild populations of Anopheles mosquitoes in Kenya, making an important stride in the fight against the disease
Fri, 01 May 2020 10:37:39 BST
The University of Glasgow has been awarded more than £1million by the Scottish Government to look into key areas, including treatments for the virus, underlying health conditions, secondary infections and the long-term effects of social distancing.
Thu, 30 Apr 2020 11:44:31 BST
New research led our CVR has provided one of the most detailed studies of coronaviruses in a patient population and could be important for predicting the behaviour of the disease at the centre of the current pandemic.
Mon, 27 Apr 2020 12:02:00 BST
Research conducted by Institute of Infection, Immunity and Inflammation scientists demonstrates the relative importance of different cell types in clearing up debris after peripheral nerve damage in the autoimmune disease.
Wed, 15 Apr 2020 10:58:00 BST
The likelihood of emerging viruses spreading to humans from animals may not depend on the specific animal reservoir of the original virus, according to new research involving the Institute's Centre for Virus Research.
Mon, 09 Mar 2020 15:54:00 GMT
Centre for Virus Research scientists, in collaboration with colleagues at the NHS Greater Glasgow & Clyde West of Scotland Specialist Virology Centre, have sequenced the genome of the SARS-COV-2 virus from the patient diagnosed as the first Scottish case.
Wed, 04 Mar 2020 11:25:00 GMT
Dr Jennifer Black, in collaboration with Prof Richard McCulloch and Institute colleagues, has identified the first protein kinase that acts in a key strategy used by the African trypanosome to survive in human and animal hosts
Wed, 05 Feb 2020 10:11:00 GMT
The Institute's Professor Sheila Graham, in collaboration with Dr Patricia Martin of Glasgow Caledonian University, has won funding to study the gap junction protein Connexin 43 in in normal and human papillomavirus-infected keratinocytes and in healing wounds.
Fri, 24 Jan 2020 12:13:35 GMT
Founded based on the joint research efforts of Prof Oded Rechavi, Shahar Bracha and iii's Dr Lilach Sheiner. FutuRx, Ramot at Tel-Aviv University, and the University of Glasgow have launched a new portfolio company to develop treatments for complex neurological diseases.
Wed, 08 Jan 2020 11:20:00 GMT
A major collaboration between the Institute's Professor Harry de Koning and groups at two Belgian universities could have important implications in the creation of much-needed advanced drugs for combatting the deadly infection in its advanced stages
Thu, 19 Dec 2019 12:09:00 GMT
Research by Institute scientists investigating virus–virus interactions and impact the population dynamics of influenza and the common cold has been published in Proceedings of the National Academy of Sciences of the United States of America (PNAS).
Fri, 06 Dec 2019 12:10:00 GMT
The Institute of Infection, Immunity and Inflammation's Professor Matthias Marti recently made a return visit to the Central American country as part of an ongoing collaboration in research and education on infectious and non-communicable diseases in the Darien and Veraguas provinces.
Fri, 15 Nov 2019 09:44:00 GMT
Research by the Institute of Infection, Immunity and Inflammation's Dr Edward Hutchison in collaboration with Astra Zeneca and published in Vaccine has used mass spectrometry to characterise the nasal flu vaccine used in schools across Scotland.
Mon, 14 Oct 2019 11:48:00 BST
The observation made by iii scientists, published in EMBO reports, has opened the door for future studies that could lead to a better understanding of migration events and ultimately limit parasite and cancer dissemination through the body
Wed, 18 Sep 2019 11:31:00 BST
According to new research published in Viruses and carried out by scientists at the Institute of Infection, Immunity and Inflammation's Centre for Virus Research (CVR), Scotland’s biting midge population carries previously-unknown viruses
Fri, 30 Aug 2019 10:09:00 BST
An exciting breakthrough in the fight to wipe out the deadly parasitic disease has been made by an international team led by University of Glasgow Institute of Molecular, Cell & Systems Biology, Institute of Infection, Immunity and Inflammation, and Wellcome Centre for Integrative Parasitology scientists
Wed, 24 Jul 2019 11:31:00 BST
Scientists from the Institute of Infection, Immunity, and Inflammation have found a new paradigm in the understanding of bacterial evolution – an important element in the wider context of antibiotic resistance
Tue, 11 Jun 2019 13:28:00 BST
Fri, 07 Jun 2019 07:48:00 BST
Boosting our natural antibody responses against the transmissible parasite stage could hold the key to combatting the malaria parasite and preventing the spread of the disease. This shows a newly published study led by Prof Matt Marti, Institute of Infection, Immunity and Inflammation and Prof Teun Bousema, Radboud University Medical Centre.
Tue, 04 Jun 2019 11:00:00 BST
Professor Iain McInnes amongst ten University of Glasgow researchers, who have been recognised as highly cited, as indicated by the number of papers they have published in the world's top 1% in their academic field.
Tue, 04 Jun 2019 10:37:00 BST
Professor Paul Garside, Chair in Basic Immunology at the Institute of Infection, Immunity and Inflammation and Dean of Global Engagement, received the Glasgow Lord Provost Award for his contribution to education.
Tue, 19 Jun 2018 16:03:00 BST
Rick Maizels, Professor of Parasitology at the Wellcome Trust Centre for Molecular Parasitology within the Institute of Infection, Immunity and Inflammation has been appointed as a Fellow of the Academy of Medical Sciences (AMS).
Tue, 19 Jun 2018 10:12:00 BST
Congratulations and very well done to the Institute’s Rheumatosphere team, who completed the Hebridean Cycle Way, covering 185 miles and travelling across ten islands over four days, from Monday 14 to Thursday 17 May.
Tue, 09 Jan 2018 16:01:00 GMT
Almost everyone knows someone with asthma. An international research consortium for asthma prevention, including collaborators from the Universities of Glasgow and Edinburgh, will search for novel approaches to potentially eliminate this lung disease in the world.
Fri, 14 Jul 2017 16:01:00 BST
Depletion of a fatty molecule in human blood propels malaria parasites to stop replicating and causing illness in people and instead to jump ship to mosquitoes to continue the transmission cycle, according to a new study by an international research team co-led by the University of Glasgow.
Fri, 11 Aug 2017 10:48:00 BST
A University of Glasgow spinout, which is developing a promising new treatment for tendon problems in humans and horses, has received a £1m investment from Mediqventure and the Scottish Investment Bank, the investment arm of Scottish Enterprise.
Tue, 06 Jun 2017 16:43:00 BST
Tue, 06 Jun 2017 17:19:00 BST
Tue, 06 Jun 2017 17:08:00 BST
Tue, 06 Jun 2017 16:54:00 BST
Tue, 28 Feb 2017 15:47:00 GMT