Professor Lars Muckli

Image of Professor Lars Muckli

Lars Muckli is Professor of Visual and Cognitive Neurosciences, and Director of fMRI at the Centre for Cognitive Neuroimaging (CCNI), in Glasgow and Co-chair of 7T-Imaging Centre of Excellence (ICE). He has worked for 20 years in the field of fMRI and multi-modal brain imaging. His work focuses on brain imaging of cortical feedback, investigation of layer specific fMRI, and multi-level cross –species computational neuroscience.

Before he came to Glasgow in 2007, Lars Muckli worked at the Max-Planck Institute for Brain Research with Rainer Goebel (1996-2000) and Wolf Singer (1996-2007). In particular his team were first to use multivariate analysis for the different cortical depth layers, and used this methods in retinotopic regions of early visual cortex when these regions were not directly visually stimulated. They found a counter-stream of information passing in primary visual cortex (V1). Feedforward information enters primary visual cortex in mid-layers (layer IV), whereas contextual feedback to V1 projects to superficial layers.

Over the last ten years Lars' team has generated important supporting evidence for the refinement of predictive coding theories. These theories are contributing to a unifying framework of brain function

List of Key Publications

  • LS Petro, AT Paton, L Muckli (2017) Contextual modulation of primary visual cortex by auditory signals Phil. Trans. R. Soc. B 372 (1714)
  • Muckli L, F De Martino, L Vizioli, LS Petro, FW Smith, K Ugurbil, R Goebel & E Yacoub (2015) Contextual feedback to superficial layers of V1. Curr Biol.
  • Vetter P, FW Smith & L Muckli, (2014) Decoding sound and imagery content in early visual cortex. Curr Biol.
  • Muckli L & LS Petro, (2013) Network interactions: non-geniculate input to V1. Curr Opin Neurobiol.
  • Smith FW & L Muckli, (2010) Nonstimulated early visual areas carry information about surrounding context, PNAS