Dr Graeme Keith
- Research Fellow (Centre for Cognitive Neuroimaging)
email:
Graeme.Keith@glasgow.ac.uk
Imaging Centre of Excellence, School of Psychology and Neuroscience, College of Medical, Veterinary and Life Sciences
Research interests
I joined the University of Glasgow as a Research Associate in MRI Physics in the lab of Professor David Porter, at the Imaging Centre of Excellence in April 2018. I previously completed a DPhil in the field of cardiac MRI and a Research Assistantship in ultra-high field MR technology at the University of Oxford. I also have an MSc in Medical Physics from the University of Aberdeen.
My current research interests are in developing powerful, novel techniques for ultra-high field MRI of the brain, which allow disease to be probed at a mechanistic level. In particular, I am involved in the development of spectroscopic techniques to measure metabolic changes in the brain, both locally and in larger regions, and in the use of non-contrast magnetic labelling methods to measure cerebral perfusion.
It is my role to work within our multi-disciplinary research team and with collaborators, providing robust, quantitative MRI methods of investigating disease.
ResearchGate: https://www.researchgate.net/profile/Graeme_Keith
Publications
2024
Keith, G. A. , Woodward, R. A., Hopkins, T., Allwood-Spiers, S., Trinder, J. , Muir, K. , Porter, D. A. and Fullerton, N. E. (2024) Towards clinical translation of 7 Tesla MRI in the human brain. IPEM-Translation, 9, 100025. (doi: 10.1016/j.ipemt.2024.100025)
Ding, B., Yan, J., Woodward, R., Allwood-Spiers, S., Williams, S. , Keith, G. , McElhinney, P. , Fullerton, N., Porter, D. and Gunamony, S. (2024) Combining Transceiver Loops with a Conventional Receive Array Increases Central SNR in Brain Imaging at 7T. 2024 ISMRM & ISMRT Annual Meeting and Exhibition (ISMRM 2024), Singapore, 4-9 May 2024. (Accepted for Publication)
Ghosalkar, J. et al. (2024) Initial Experience in pCASL Using a Novel Neurovascular Coil at 7T. 2024 ISMRM & ISMRT Annual Meeting and Exhibition (ISMRM 2024), Singapore, 4-9 May 2024. (Accepted for Publication)
Keith, G. , Williams, S. , Ding, B., Trinder, J. , Seginer, A., Schmidt, R., Gunamony, S. , Fullerton, N. and Porter, D. (2024) B1+ Shimming in 1H RS-COKE Spectroscopic Imaging in the Human Brain at 7T. 2024 ISMRM & ISMRT Annual Meeting and Exhibition (ISMRM 2024), Singapore, 4-9 May 2024. (Accepted for Publication)
Winata, S. , Hoinkiss, D., Keith, G. , Williams, S. , Ding, B., Al-Wasity, S. and Porter, D. (2024) Real-time Multislice-to-volume Motion Correction with B1+ Shimming for Task-based Functional MRI at 7T. 2024 ISMRM & ISMRT Annual Meeting and Exhibition (ISMRM 2024), Singapore, 4-9 May 2024. (Accepted for Publication)
2023
Winata, S. , Hoinkiss, D.C., Keith, G.A. , Al-Wasity, S. and Porter, D.A. (2023) Real-time Multislice-to-volume Motion Correction for Task-based Functional MRI at 7T. 39th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2023), Basel, Switzerland, 4-7 October 2023. pp. 65-66.
Winata, S. , Hoinkiss, D.C., Keith, G.A. , Williams, S.N. , Ding, B.Y., Al-Wasity, S., Gunamony, S. and Porter, D.A. (2023) Parallel Transmit Imaging with Real-time Multislice-to-volume Motion Correction for Task-based Functional MRI at 7T. 39th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2023), Basel, Switzerland, 4-7 October 2023. pp. 214-15.
Winata, S. , Hoinkiss, D. C., Keith, G. , Al-Wasity, S. and Porter, D. (2023) Prospective Motion Correction for Functional MRI at 7T using Multislice-to-Volume Image Registration. Organization for Human Brain Mapping Annual Meeting 2023, Montreal, QC, Canada, 22-26 Jul 2023.
Winata, S. , Hoinkiss, D., Keith, G. , Al-Wasity, S. and Porter, D. (2023) Real-time Image-based Motion Correction for 7T Task-based Functional MRI. SINAPSE 15th Annual Scientific Meeting, Glasgow, Scotland, 14 Jun 2023.
Winata, S. , Hoinkiss, D. C., Keith, G. A. , Al-Wasity, S. M. and Porter, D. A. (2023) Multislice-to-Volume Prospective Motion Correction for Functional MRI Protocols at 7T. ISMRM & ISMRT Annual Meeting & Exhibition 2023, Toronto, ON, Canada, 03-08 Jun 2023.
2022
Seginer, A., Keith, G. A. , Porter, D. A. and Schmidt, R. (2022) Artifact suppression in readout‐segmented consistent K‐t space EPSI (RS‐COKE) for fast 1 H spectroscopic imaging at 7 T. Magnetic Resonance in Medicine, 88(6), pp. 2339-2357. (doi: 10.1002/mrm.29373) (PMID:35975965)
Winata, S. , Hoinkiss, D. C., Keith, G. and Porter, D. (2022) Multislice-to-Volume Registration for Detecting Intra-Volume Motion in 7T EPI. 28th Organisation of Human Brain Mapping Annual Meeting, Glasgow, Scotland, 19-23 June 2022.
Seginer, A., Keith, G. A. , Porter, D. A. and Schmidt, R. (2022) Reducing Artifacts in Readout-Segmented Spectroscopic Imaging at 7T. ISMRT 31st Annual Meeting, London, UK, 7-12 May 2022.
2021
Winata, S. , Hoinkiss, D.C., Keith, G. A. , Porter, D. A. and Gunther, M. (2021) Navigator Parameter Optimisation for MS-PACE Prospective Motion Correction. ISMRM British and Irish Chapter Annual Meeting - MR-Fest "A Celebration of Magnetic Resonance", 13-17 Sept 2021.
Winata, S. , Hoinkiss, D.C., Keith, G. A. , Porter, D. A. and Gunther, M. (2021) Optimising Navigator Scans for Use in MRI Prospective Motion Correction. 13th SINAPSE Annual Scientific Meeting, 16-17 Sept 2021.
Winata, S. , Hoinkiss, D.C., Keith, G. A. , Porter, D. A. and Gunther, M. (2021) Image Registration Shortcut for Prospective Motion Correction Using Unseparated Multiband Slices. 38th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2021), 7–9 Oct 2021. (doi: 10.1007/s10334-021-00947-8)
Keith, G. , Seginer, A., Porter, D. and Schmidt, R. (2021) Echo-planar Spectroscopic Imaging with Readout-segmented COKE at 7T: Artifact Analysis using a Purpose-Built Phantom and Simulation. ISMRM & SMRT Annual Meeting & Exhibition, 15-20 May 2021.
Winata, S. , Hoinkiss, D.C., Keith, G. A. , Porter, D. A. and Gunther, M. (2021) Optimisation of Navigator Parameter for MS-PACE Prospective Motion Correction. Postgraduate Meeting of British-Irish and Iberian Chapters of ISMRM, 15-16 April 2021.
2020
Keith, G. (2020) Readout-Segmented COKE: A Technique for Echo-Planar Spectroscopic Imaging at 7 Tesla with High Spectral Bandwidth and Suppression of Nyquist Errors in the Spectral Domain. ESMRMB 2020, 30 September - 2 October 2020.
2019
Keith, G. , Vicari, M., Woodward, R. and Porter, D. (2019) In Vivo Echo-Planar Spectroscopic Imaging (EPSI) at 7 Tesla with Readout Segmentation for Improved Spectral Bandwidth. ISMRM 27th Annual Meeting & Exhibition, Montreal, Quebec, Canada, 11-16 May 2019.
Keith, G. (2019) Imaging at ultra-high field: a new era in clinical MRI? European Medical Physics News, 2019(Mar 10), pp. 25-28.
2017
Keith, G. A. , Rodgers, C. T., Chappell, M. A. and Robson, M. D. (2017) A look-locker acquisition scheme for quantitative myocardial perfusion imaging with FAIR arterial spin labeling in humans at 3 tesla. Magnetic Resonance in Medicine, 78(2), pp. 541-549. (doi: 10.1002/mrm.26388) (PMID:27604183) (PMCID:PMC5516148)
2016
Keith, G. , Rodgers, C., Chappell, M. and Robson, M. (2016) Reproducibility and Variability of a Look-Locker FAIR ASL Sequence for Quantitative Measurement of Myocardial Blood Flow in Healthy Human Volunteers at 3T. ISMRM 24th Annual Meeting & Exhibition, Singapore, 7-13 May 2016.
2015
Keith, G. A. , Rodgers, C. T., Chappell, M. A. and Robson, M. D. (2015) A Look-Locker Acquisition Scheme for Quantitative Myocardial Perfusion Imaging by Arterial Spin Labelling in Humans at 3 T. ISMRM 23rd Annual Meeting & Exhibition, Toronto, Ontario, Canada, 30 May - 5 June 2015.
Keith, G. A. , Rodgers, C. T., Hess, A. T., Snyder, C. J., Vaughan, J. T. and Robson, M. D. (2015) Automated tuning of an eight‐channel cardiac transceive array at 7 tesla using piezoelectric actuators. Magnetic Resonance in Medicine, 73(6), pp. 2390-2397. (doi: 10.1002/mrm.25356) (PMID:24986525) (PMCID:PMC4245186)
Tao, Y., Hess, A. T., Keith, G. A. , Rodgers, C. T., Liu, A., Francis, J. M., Neubauer, S. and Robson, M. D. (2015) Optimized saturation pulse train for human first‐pass myocardial perfusion imaging at 7T. Magnetic Resonance in Medicine, 73(4), pp. 1450-1456. (doi: 10.1002/mrm.25262) (PMID:24753130) (PMCID:PMC4377098)
2014
Tao, Y., Hess, A. T., Keith, G. A. , Rodgers, C., Liu, A., Francis, J. M., Neubauer, S. and Robson, M. D. (2014) HS8 Saturation Pulse Train for First-Pass Myocardial Perfusion Imaging at 7Ts. Joint Annual Meeting ISMRM-ESMRMB, Milan, Italy, 10-16 May 2014.
Keith, G. A. , Rodgers, C. T., Hess, A. T., Snyder, C. J., Vaughan, J. T. and Robson, M. D. (2014) A Fully Integrated Automatic Tune and Match System for an 8-Channel Transmit/Receive Cardiac TEM Array at 7T: Initial Results in a Phantom and Volunteers. Joint Annual Meeting ISMRM-ESMRMB, Milan, Italy, 10-16 May 2014.
2013
Rodgers, C. T., Keith, G. A. , Hess, A. T., Snyder, C. J. and Robson, M. D. (2013) An Algorithm for Automatic Optimisation of Transmit Array Coil Tune and Match Applied in a Cardiac TEM Coil at 7T. ISMRM 21st Annual Meeting & Exhibition, Salt Lake City, Utah, USA, 20-26 April 2013.
Hess, A. T., Snyder, C. J., Keith, G. A. , Rodgers, C. T., Neubauer, S. and Robson, M. D. (2013) Coil Tuning with Piezoelectric Actuators Using the MRI Signal as the Optimization Parameter. ISMRM 21st Annual Meeting & Exhibition, Salt Lake City, Utah, USA, 20-26 April 2013.
Keith, G. A. , Rodgers, C. T., Hess, A. T., Snyder, C. J. and Robson, M. D. (2013) Computerised Tuning of an 8-Channel Cardiac TEM Array at 7T: An Integrated System Using Piezoelectric Actuators and Power Monitors. ISMRM 21st Annual Meeting & Exhibition, Salt Lake City, Utah, USA, 20-26 April 2013.
Tao, Y., Hess, A. T., Keith, G. A. , Rodgers, C. T. and Robson, M. D. (2013) B0-Independent Quantitative Measurement of Low B1 Field for Human Cardiac MRI at 7T. ISMRM 21st Annual Meeting & Exhibition, Salt Lake City, Utah, USA, 20-26 April 2013.
Articles
Keith, G. A. , Woodward, R. A., Hopkins, T., Allwood-Spiers, S., Trinder, J. , Muir, K. , Porter, D. A. and Fullerton, N. E. (2024) Towards clinical translation of 7 Tesla MRI in the human brain. IPEM-Translation, 9, 100025. (doi: 10.1016/j.ipemt.2024.100025)
Seginer, A., Keith, G. A. , Porter, D. A. and Schmidt, R. (2022) Artifact suppression in readout‐segmented consistent K‐t space EPSI (RS‐COKE) for fast 1 H spectroscopic imaging at 7 T. Magnetic Resonance in Medicine, 88(6), pp. 2339-2357. (doi: 10.1002/mrm.29373) (PMID:35975965)
Keith, G. (2019) Imaging at ultra-high field: a new era in clinical MRI? European Medical Physics News, 2019(Mar 10), pp. 25-28.
Keith, G. A. , Rodgers, C. T., Chappell, M. A. and Robson, M. D. (2017) A look-locker acquisition scheme for quantitative myocardial perfusion imaging with FAIR arterial spin labeling in humans at 3 tesla. Magnetic Resonance in Medicine, 78(2), pp. 541-549. (doi: 10.1002/mrm.26388) (PMID:27604183) (PMCID:PMC5516148)
Keith, G. A. , Rodgers, C. T., Hess, A. T., Snyder, C. J., Vaughan, J. T. and Robson, M. D. (2015) Automated tuning of an eight‐channel cardiac transceive array at 7 tesla using piezoelectric actuators. Magnetic Resonance in Medicine, 73(6), pp. 2390-2397. (doi: 10.1002/mrm.25356) (PMID:24986525) (PMCID:PMC4245186)
Tao, Y., Hess, A. T., Keith, G. A. , Rodgers, C. T., Liu, A., Francis, J. M., Neubauer, S. and Robson, M. D. (2015) Optimized saturation pulse train for human first‐pass myocardial perfusion imaging at 7T. Magnetic Resonance in Medicine, 73(4), pp. 1450-1456. (doi: 10.1002/mrm.25262) (PMID:24753130) (PMCID:PMC4377098)
Conference or Workshop Item
Ding, B., Yan, J., Woodward, R., Allwood-Spiers, S., Williams, S. , Keith, G. , McElhinney, P. , Fullerton, N., Porter, D. and Gunamony, S. (2024) Combining Transceiver Loops with a Conventional Receive Array Increases Central SNR in Brain Imaging at 7T. 2024 ISMRM & ISMRT Annual Meeting and Exhibition (ISMRM 2024), Singapore, 4-9 May 2024. (Accepted for Publication)
Ghosalkar, J. et al. (2024) Initial Experience in pCASL Using a Novel Neurovascular Coil at 7T. 2024 ISMRM & ISMRT Annual Meeting and Exhibition (ISMRM 2024), Singapore, 4-9 May 2024. (Accepted for Publication)
Keith, G. , Williams, S. , Ding, B., Trinder, J. , Seginer, A., Schmidt, R., Gunamony, S. , Fullerton, N. and Porter, D. (2024) B1+ Shimming in 1H RS-COKE Spectroscopic Imaging in the Human Brain at 7T. 2024 ISMRM & ISMRT Annual Meeting and Exhibition (ISMRM 2024), Singapore, 4-9 May 2024. (Accepted for Publication)
Winata, S. , Hoinkiss, D., Keith, G. , Williams, S. , Ding, B., Al-Wasity, S. and Porter, D. (2024) Real-time Multislice-to-volume Motion Correction with B1+ Shimming for Task-based Functional MRI at 7T. 2024 ISMRM & ISMRT Annual Meeting and Exhibition (ISMRM 2024), Singapore, 4-9 May 2024. (Accepted for Publication)
Winata, S. , Hoinkiss, D.C., Keith, G.A. , Al-Wasity, S. and Porter, D.A. (2023) Real-time Multislice-to-volume Motion Correction for Task-based Functional MRI at 7T. 39th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2023), Basel, Switzerland, 4-7 October 2023. pp. 65-66.
Winata, S. , Hoinkiss, D.C., Keith, G.A. , Williams, S.N. , Ding, B.Y., Al-Wasity, S., Gunamony, S. and Porter, D.A. (2023) Parallel Transmit Imaging with Real-time Multislice-to-volume Motion Correction for Task-based Functional MRI at 7T. 39th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2023), Basel, Switzerland, 4-7 October 2023. pp. 214-15.
Winata, S. , Hoinkiss, D. C., Keith, G. , Al-Wasity, S. and Porter, D. (2023) Prospective Motion Correction for Functional MRI at 7T using Multislice-to-Volume Image Registration. Organization for Human Brain Mapping Annual Meeting 2023, Montreal, QC, Canada, 22-26 Jul 2023.
Winata, S. , Hoinkiss, D., Keith, G. , Al-Wasity, S. and Porter, D. (2023) Real-time Image-based Motion Correction for 7T Task-based Functional MRI. SINAPSE 15th Annual Scientific Meeting, Glasgow, Scotland, 14 Jun 2023.
Winata, S. , Hoinkiss, D. C., Keith, G. A. , Al-Wasity, S. M. and Porter, D. A. (2023) Multislice-to-Volume Prospective Motion Correction for Functional MRI Protocols at 7T. ISMRM & ISMRT Annual Meeting & Exhibition 2023, Toronto, ON, Canada, 03-08 Jun 2023.
Winata, S. , Hoinkiss, D. C., Keith, G. and Porter, D. (2022) Multislice-to-Volume Registration for Detecting Intra-Volume Motion in 7T EPI. 28th Organisation of Human Brain Mapping Annual Meeting, Glasgow, Scotland, 19-23 June 2022.
Seginer, A., Keith, G. A. , Porter, D. A. and Schmidt, R. (2022) Reducing Artifacts in Readout-Segmented Spectroscopic Imaging at 7T. ISMRT 31st Annual Meeting, London, UK, 7-12 May 2022.
Winata, S. , Hoinkiss, D.C., Keith, G. A. , Porter, D. A. and Gunther, M. (2021) Navigator Parameter Optimisation for MS-PACE Prospective Motion Correction. ISMRM British and Irish Chapter Annual Meeting - MR-Fest "A Celebration of Magnetic Resonance", 13-17 Sept 2021.
Winata, S. , Hoinkiss, D.C., Keith, G. A. , Porter, D. A. and Gunther, M. (2021) Optimising Navigator Scans for Use in MRI Prospective Motion Correction. 13th SINAPSE Annual Scientific Meeting, 16-17 Sept 2021.
Winata, S. , Hoinkiss, D.C., Keith, G. A. , Porter, D. A. and Gunther, M. (2021) Image Registration Shortcut for Prospective Motion Correction Using Unseparated Multiband Slices. 38th Annual Scientific Meeting of the European Society for Magnetic Resonance in Medicine and Biology (ESMRMB 2021), 7–9 Oct 2021. (doi: 10.1007/s10334-021-00947-8)
Keith, G. , Seginer, A., Porter, D. and Schmidt, R. (2021) Echo-planar Spectroscopic Imaging with Readout-segmented COKE at 7T: Artifact Analysis using a Purpose-Built Phantom and Simulation. ISMRM & SMRT Annual Meeting & Exhibition, 15-20 May 2021.
Winata, S. , Hoinkiss, D.C., Keith, G. A. , Porter, D. A. and Gunther, M. (2021) Optimisation of Navigator Parameter for MS-PACE Prospective Motion Correction. Postgraduate Meeting of British-Irish and Iberian Chapters of ISMRM, 15-16 April 2021.
Keith, G. (2020) Readout-Segmented COKE: A Technique for Echo-Planar Spectroscopic Imaging at 7 Tesla with High Spectral Bandwidth and Suppression of Nyquist Errors in the Spectral Domain. ESMRMB 2020, 30 September - 2 October 2020.
Keith, G. , Vicari, M., Woodward, R. and Porter, D. (2019) In Vivo Echo-Planar Spectroscopic Imaging (EPSI) at 7 Tesla with Readout Segmentation for Improved Spectral Bandwidth. ISMRM 27th Annual Meeting & Exhibition, Montreal, Quebec, Canada, 11-16 May 2019.
Keith, G. , Rodgers, C., Chappell, M. and Robson, M. (2016) Reproducibility and Variability of a Look-Locker FAIR ASL Sequence for Quantitative Measurement of Myocardial Blood Flow in Healthy Human Volunteers at 3T. ISMRM 24th Annual Meeting & Exhibition, Singapore, 7-13 May 2016.
Keith, G. A. , Rodgers, C. T., Chappell, M. A. and Robson, M. D. (2015) A Look-Locker Acquisition Scheme for Quantitative Myocardial Perfusion Imaging by Arterial Spin Labelling in Humans at 3 T. ISMRM 23rd Annual Meeting & Exhibition, Toronto, Ontario, Canada, 30 May - 5 June 2015.
Tao, Y., Hess, A. T., Keith, G. A. , Rodgers, C., Liu, A., Francis, J. M., Neubauer, S. and Robson, M. D. (2014) HS8 Saturation Pulse Train for First-Pass Myocardial Perfusion Imaging at 7Ts. Joint Annual Meeting ISMRM-ESMRMB, Milan, Italy, 10-16 May 2014.
Keith, G. A. , Rodgers, C. T., Hess, A. T., Snyder, C. J., Vaughan, J. T. and Robson, M. D. (2014) A Fully Integrated Automatic Tune and Match System for an 8-Channel Transmit/Receive Cardiac TEM Array at 7T: Initial Results in a Phantom and Volunteers. Joint Annual Meeting ISMRM-ESMRMB, Milan, Italy, 10-16 May 2014.
Rodgers, C. T., Keith, G. A. , Hess, A. T., Snyder, C. J. and Robson, M. D. (2013) An Algorithm for Automatic Optimisation of Transmit Array Coil Tune and Match Applied in a Cardiac TEM Coil at 7T. ISMRM 21st Annual Meeting & Exhibition, Salt Lake City, Utah, USA, 20-26 April 2013.
Hess, A. T., Snyder, C. J., Keith, G. A. , Rodgers, C. T., Neubauer, S. and Robson, M. D. (2013) Coil Tuning with Piezoelectric Actuators Using the MRI Signal as the Optimization Parameter. ISMRM 21st Annual Meeting & Exhibition, Salt Lake City, Utah, USA, 20-26 April 2013.
Keith, G. A. , Rodgers, C. T., Hess, A. T., Snyder, C. J. and Robson, M. D. (2013) Computerised Tuning of an 8-Channel Cardiac TEM Array at 7T: An Integrated System Using Piezoelectric Actuators and Power Monitors. ISMRM 21st Annual Meeting & Exhibition, Salt Lake City, Utah, USA, 20-26 April 2013.
Tao, Y., Hess, A. T., Keith, G. A. , Rodgers, C. T. and Robson, M. D. (2013) B0-Independent Quantitative Measurement of Low B1 Field for Human Cardiac MRI at 7T. ISMRM 21st Annual Meeting & Exhibition, Salt Lake City, Utah, USA, 20-26 April 2013.
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- 7T Imaging in Patients with MND to find Non-Invasive Disease Biomarkers for Disease and Genetic Subtypes
Neurosciences Foundation
2024 - 2026
- Development of a Novel Head Coil for Clinical Neuroimaging in 7 Tesla MRI Scanners
Innovate UK
2021 - 2023
- Probing the Rheumatoid Arthritis Brain to Expose Central Pain Pathways
Versus Arthritis
2020 - 2022