Protein Structure & Regulation  

Our research aim is to answer fundamental questions related to the structure and function of proteins involved in important biochemical processes.




Liu, W., Giuriani, G., Havlikova, A., Li, D., Lamont, D. J., Neugart, S., Velanis, C. N., Petersen, J., Hoecker, U., Christie, J. M., Jenkins, G. (2024) Phosphorylation of Arabidopsis UVR8 photoreceptor modulates protein interactions and responses to UV-B radiation. Nature Communications, 15, (doi: 10.1038/s41467-024-45575-7)

Baena, G., Xia, L., Waghmare, S., Yu, Z., Guo, Y., Blatt, M. R., Zhang, B., Karnik, R. (2024) Arabidopsis SNARE SYP132 impacts on PIP2;1 trafficking and function in salinity stress. Plant Journal, (doi: 10.1111/tpj.16649)

Blatt, M. R. (2024) A charged existence: a century of transmembrane ion transport in plants. Plant Physiology, (doi: 10.1093/plphys/kiad630)


Silva-Alvim, F. A.L., Alvim, J. C., Harvey, A., Blatt, M. R. (2023) Speedy stomata of a C4 plant correlate with enhanced K+ channel gating. Plant, Cell and Environment, (doi: 10.1111/pce.14775)

Nguyen, T.-H., Silva-Alvim, F. A. L., Hills, A., Blatt, M. R. (2023) OnGuard3e: a predictive, ecophysiology‐ready tool for gas exchange and photosynthesis research. Plant, Cell and Environment, 46, pp. 3644-3658. (doi: 10.1111/pce.14674)

Quint, M. et al. (2023) 25 years of thermomorphogenesis research: milestones and perspectives. Trends in Plant Science, 28, pp. 1089-1100. (doi: 10.1016/j.tplants.2023.07.001)

Nguyen, T. B.-A., Lefoulon, C., Nguyen, T.-H., Blatt, M. R., Carroll, W. (2023) Engineering stomata for enhanced carbon capture and water-use efficiency. Trends in Plant Science, (doi: 10.1016/j.tplants.2023.06.002)

Karnik, R., Blatt, M. R. (2023) Analyzing protein–protein interactions using the split-ubiquitin system. Humana Press

Agirre, J. et al. (2023) The CCP 4 suite: integrative software for macromolecular crystallography. Acta Crystallographica. Section D: Structural Biology, D79, pp. 449-461. (doi: 10.1107/S2059798323003595)

Horiuchi, K., Uragami, C., Tao, R., Kosumi, D., Cogdell, R. J., Hashimoto, H. (2023) Excited-state dynamics of all the mono-cis and the major di-cis isomers of β-apo-8′-carotenal as revealed by femtosecond time-resolved transient absorption spectroscopy. Molecules, 28, (doi: 10.3390/molecules28114424)

Deni, I. et al. (2023) Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome. Cell Chemical Biology, 30, pp. 470-485.e6. (doi: 10.1016/j.chembiol.2023.03.002)

Javitt, A. et al. (2023) The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC. Nature Cancer, 4, pp. 629-647. (doi: 10.1038/s43018-023-00557-4)

Waksman, T., Suetsugu, N., Hermanowicz, P., Ronald, J., Sullivan, S., Łabuz, J., Christie, J. M. (2023) Phototropin phosphorylation of ROOT PHOTOTROPISM 2 and its role in mediating phototropism, leaf positioning and chloroplast accumulation movement in arabidopsis. Plant Journal, 114, pp. 390-402. (doi: 10.1111/tpj.16144)

Cupellini, L., Qian, P., Nguyen-Phan, T. C., Gardiner, A. T., Cogdell, R. J. (2023) Quantum chemical elucidation of a sevenfold symmetric bacterial antenna complex. Photosynthesis Research, 156, pp. 75-87. (doi: 10.1007/s11120-022-00925-8)

Adam, S., Zheng, D., Klein, A., Volz, C., Mullen, W., Shirran, S. L., Smith, B. O., Kalinina, O. V., Müller, R., Koehnke, J. (2023) Unusual peptide-binding proteins guide pyrroloindoline alkaloid formation in crocagin biosynthesis. Nature Chemistry, 15, pp. 560-568. (doi: 10.1038/s41557-023-01153-w)

Abioye, J., Lawson‐Williams, M., Lecanda, A., Calhoon, B., McQue, A. L., Colloms, S. D., Stark, W. M., Olorunniji, F. J. (2023) High fidelity one‐pot DNA assembly using orthogonal serine integrases. Biotechnology Journal, 18, (doi: 10.1002/biot.202200411)

Lemonidis, K., Rennie, M. L., Arkinson, C., Chaugule, V. K., Clarke, M., Streetley, J., Walden, H. (2023) Structural and biochemical basis of interdependent FANCI-FANCD2 ubiquitination. EMBO Journal, 42, (doi: 10.15252/embj.2022111898)

Gallusci, P., Agius, D. R., Moschou, P. N., Dobránszki, J., Kaiserli, E., Martinelli, F. (2023) Deep inside the epigenetic memories of stressed plants. Trends in Plant Science, 28, pp. 142-153. (doi: 10.1016/j.tplants.2022.09.004)

Cannone, G., Kompaniiets, D., Graham, S., White, M. F., Spagnolo, L. (2023) Structure of the Saccharolobus solfataricus type III-D CRISPR effector. Current Research in Structural Biology, 5, (doi: 10.1016/j.crstbi.2023.100098)

McInnes, K. J., van der Hooft, J. J.J., Sharma, A., Herzyk, P., Hundleby, P. A.C., Schoonbeek, H.-J., Amtmann, A., Ridout, C., Jenkins, G. I. (2023) Overexpression of Brassica napus COMT1 in Arabidopsis heightens UV-B-mediated resistance to Plutella xylostella herbivory. Photochemical and Photobiological Sciences, 22, pp. 2341-2356. (doi: 10.1007/s43630-023-00455-9)


Seale, M., Zhdanov, O., Soons, M. B., Cummins, C., Kroll, E., Blatt, M. R., Zare-Behtash, H., Busse, A., Mastropaolo, E., Bullock, J. M., Viola, I. M., Nakayama, N. (2022) Environmental morphing enables informed dispersal of the dandelion diaspore. eLife, 11, (doi: 10.7554/eLife.81962)

Elvers, I., Nguyen Phan, T. C., Gardiner, A. T., Hunter, C. N., Cogdell, R. J., Köhler, J. (2022) Phasor analysis reveals multicomponent fluorescence kinetics in the LH2 complex from Marichromatium purpuratum. Journal of Physical Chemistry B, 126, pp. 10335-10346. (doi: 10.1021/acs.jpcb.2c04983)

Duan, H.-G., Jha, A., Chen, L., Tiwari, V., Cogdell, R. J., Ashraf, K., Prokhorenko, V. I., Thorwart, M., Miller, R. J. D. (2022) Quantum coherent energy transport in the Fenna–Matthews–Olson complex at low temperature. Proceedings of the National Academy of Sciences of the United States of America, 119, pp. e2212630119. (doi: 10.1073/pnas.2212630119)

Kowalczyk, D., Nakasone, M. A., Smith, B. O., Huang, D. T. (2022) Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function. Life Science Alliance, 5, (doi: 10.26508/lsa.202201472)

Lieberman-Lazarovich, M., Kaiserli, E., Bucher, E., Mladenov, V. (2022) Natural and induced epigenetic variation for crop improvement. Current Opinion in Plant Biology, 70, (doi: 10.1016/j.pbi.2022.102297)

Wu, F., Finkelstein-Shapiro, D., Wang, M., Rosenkampff, I., Yartsev, A., Pascher, T., Nguyen- Phan, T. C., Cogdell, R., Börjesson, K., Pullerits, T. (2022) Optical cavity-mediated exciton dynamics in photosynthetic light harvesting 2 complexes. Nature Communications, 13, (doi: 10.1038/s41467-022-34613-x)

Horaruang, W., Klejchová, M., Carroll, W., Silva-Alvim, F. A.L., Waghmare, S., Papanatsiou, M., Amtmann, A., Hills, A., Alvim, J. C., Blatt, M. R., Zhang, B. (2022) Engineering a K+ channel 'sensory antenna' enhances stomatal kinetics, water use efficiency and photosynthesis. Nature Plants, 8, pp. 1262-1274. (doi: 10.1038/s41477-022-01255-2)

Fang, W., Vellutini, E., Perrella, G., Kaiserli, E. (2022) TANDEM ZINC-FINGER/PLUS3 regulates phytochrome B abundance and signaling to fine-tune hypocotyl growth. Plant Cell, 34, pp. 4213-4231. (doi: 10.1093/plcell/koac236)

Gracie, J., Zamberlan, F., Andrews, I. B., Smith, B. O., Peveler, W. J. (2022) Growth of plasmonic nanoparticles for aging cask-matured whisky. ACS Applied Nano Materials, 5, pp. 15362-15368. (doi: 10.1021/acsanm.2c03406)

Miguel-Romero, L., Alqasmi, M., Bacarizo, J., Tan, J. A., Cogdell, R. J., Chen, J., Byron, O., Christie, G. E., Marina, A., Penadés, J. R. (2022) Non-canonical Staphylococcus aureus pathogenicity island repression. Nucleic Acids Research, 50, pp. 11109-11127. (doi: 10.1093/nar/gkac855)

Qian, P., Nguyen-Phan, T. C., Gardiner, A. T., Croll, T. I., Roszak, A. P., Southall, J., Jackson, P. J., Vasilev, C., Castro-Hartmann, P., Sader, K., Hunter, C. N., Cogdell, R. J. (2022) Cryo-EM structures of light-harvesting 2 complexes from Rhodopseudomonas palustris reveal the molecular origin of absorption tuning. Proceedings of the National Academy of Sciences of the United States of America, 117, (doi: 10.1073/pnas.2210109119)

Patitaki, E., Schivre, G., Zioutopoulou, A., Perrella, G., Bourbousse, C., Barneche, F., Kaiserli, E. (2022) Light, chromatin, action: nuclear events regulating light signaling in Arabidopsis. New Phytologist, 236, pp. 333-349. (doi: 10.1111/nph.18424)

Rennie, M. L., Arkinson, C., Chaugule, V. K., Walden, H. (2022) Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Science Advances, 8, (doi: 10.1126/sciadv.abq6353)

Ryan, S. M., Ruscher, R., Johnston, W. A., Pickering, D. A., Kennedy, M. W., Smith, B. O., Jones, L., Buitrago, G., Field, M. A., Esterman, A. J., McHugh, C. P., Browne, D. J., Cooper, M. M., Ryan, R. Y. M., Doolan, D. L., Engwerda, C. R., Miles, K., Mitreva, M., Croese, J., Rahman, T., Alexandrov, K., Giacomin, P. R., Loukas, A. (2022) Novel antiinflammatory biologics shaped by parasite–host coevolution. Proceedings of the National Academy of Sciences of the United States of America, 119, (doi: 10.1073/pnas.2202795119)

Hogrel, G., Guild, A., Graham, S., Rickman, H., Grüschow, S., Bertrand, Q., Spagnolo, L., White, M. F. (2022) Cyclic nucleotide-induced helical structure activates a TIR immune effector. Nature, 608, pp. 808-812. (doi: 10.1038/s41586-022-05070-9)

Lemonidis, K., Arkinson, C., Rennie, M. L., Walden, H. (2022) Mechanism, specificity and function of FANCD2‐FANCI ubiquitination and deubiquitination. FEBS Journal, 289, pp. 4811-4829. (doi: 10.1111/febs.16077)

Caccavale, E., Johnson, M. P., Brijbassi, S., Andreazza, A. C., Tokatlidis, K. (2022) Mitochondria and Us: from exploration to global collective. Biochemist, 44, pp. 22-28. (doi: 10.1042/bio_2022_122)

Liao, X., Jenkins, G. I. (2022) Cysteines have a role in conformation of the UVR8 photoreceptor. Plant Journal, 111, pp. 583-594. (doi: 10.1111/tpj.15841)

Baena, G., Xia, L., Waghmare, S., Karnik, R. (2022) SNARE SYP132 mediates divergent trafficking of H+-ATPase AHA1 and antimicrobial PR1 during bacterial pathogenesis. Plant Physiology, 189, pp. 1639-1661. (doi: 10.1093/plphys/kiac149)

Kjeldsen, A., Kay, J. E., Baxter, S., McColm, S., Serrano-Amatriain, C., Parker, S., Robb, E., Arnold, S. A., Gilmour, C., Raper, A., Robertson, G., Fleming, R., Smith, B. O., Fotheringham, I. G., Christie, J. M., Magneschi, L. (2022) The fluorescent protein iLOV as a reporter for screening of high‐yield production of antimicrobial peptides in Pichia pastoris. Microbial Biotechnology, 15, pp. 2126-2139. (doi: 10.1111/1751-7915.14034)

Ledahawsky, L. M., Terzenidou, M. E., Edwards, R., Kline, R. A., Graham, L. C., Eaton, S. L., van der Hoorn, D., Chaytow, H., Huang, Y.‐T., Groen, E. J.N., Motyl, A. A. L., Lamont, D. J., Tokatlidis, K., Wishart, T. M., Gillingwater, T. H. (2022) The mitochondrial protein Sideroflexin 3 (SFXN3) influences neurodegeneration pathways in vivo. FEBS Journal, 289, pp. 3894-3914. (doi: 10.1111/febs.16377)

Wang, Y., Karnik, R., Garcia-Mata, C., Hu, H. (2022) Editorial: transport and membrane traffic in stomatal biology. Frontiers in Plant Science, 13, (doi: 10.3389/fpls.2022.898128)

Torres Cabán, C. C., Yang, M., Lai, C., Yang, L., Subach, F. V., Smith, B. O., Piatkevich, K. D., Boyden, E. S. (2022) Tuning the sensitivity of genetically encoded fluorescent potassium indicators through structure-guided and genome mining strategies. ACS Sensors, 7, pp. 1336-1346. (doi: 10.1021/acssensors.1c02201)

Thu, N. B.A., Amtmann, A., Blatt, M. R., Nguyen, T.-H. (2022) Stomata under salt stress—what can mechanistic modeling tell us? Academic Press

Živković, D., Sanchez Dafun, A., Menneteau, T., Schahl, A., Lise, S., Kervarrec, C., Toste Rêgo, A., da Fonseca, P. C. A., Chavent, M., Pineau, C., Burlet-Schiltz, O., Marcoux, J., Bousquet, M.-P. (2022) Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis. Proceedings of the National Academy of Sciences of the United States of America, 119, pp. e2116826119. (doi: 10.1073/pnas.2116826119)

Tibbo, A. J., Mika, D., Dobi, S., Ling, J., McFall, A., Tejeda, G. S., Blair, C., MacLeod, R., MacQuaide, N., Gök, C., Fuller, W., Smith, B. O., Smith, G. L., Vandecasteele, G., Brand, T., Baillie, G. S. (2022) Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins. Journal of Molecular and Cellular Cardiology, 165, pp. 86-102. (doi: 10.1016/j.yjmcc.2022.01.001)

Zioutopoulou, A., Patitaki, E., O'Donnell, L., Kaiserli, E. (2022) Low fluence ultraviolet-B promotes ultraviolet resistance 8-modulated flowering in Arabidopsis. Frontiers in Plant Science, 13, (doi: 10.3389/fpls.2022.840720)

Naqvi, S., He, Q., Trusch, F., Qiu, H., Pham, J., Sun, Q., Christie, J. M., Gilroy, E. M., Birch, P. R.J. (2022) Blue‐light receptor phototropin 1 suppresses immunity to promote Phytophthora infestans infection. New Phytologist, 233, pp. 2282-2293. (doi: 10.1111/nph.17929)

Dunkerley, K. M., Rintala-Dempsey, A. C., Salzano, G., Tadayon, R., Hadi, D., Barber, K. R., Walden, H., Shaw, G. S. (2022) Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by Parkin. Biochemical Journal, 479, pp. 751-766. (doi: 10.1042/bcj20210741)

Guarino, F., Cicatelli, A., Castiglione, S., Agius, D. R., Orhun, G. E., Fragkostefanakis, S., Leclercq, J., Dobránszki, J., Kaiserli, E., Lieberman-Lazarovich, M., Sõmera, M., Sarmiento, C., Vettori, C., Paffetti, D., Poma, A. M. G., Moschou, P. N., Gašparović, M., Yousefi, S., Vergata, C., Berger, M. M. J., Gallusci, P., Miladinović, D., Martinelli, F. (2022) An epigenetic alphabet of crop adaptation to climate change. Frontiers in Genetics, 13, (doi: 10.3389/fgene.2022.818727)

Kim, J., Nguyen-Phan, T. C., Gardiner, A. T., Yoon, T. H., Cogdell, R. J., Cho, M., Scholes, G. D. (2022) Vibrational modes promoting exciton relaxation in the B850 band of LH2. Journal of Physical Chemistry Letters, 13, pp. 1099-1106. (doi: 10.1021/acs.jpclett.1c03868)

Blatt, M. R., Jezek, M., Lew, V. L., Hills, A. (2022) What can mechanistic models tell us about guard cells, photosynthesis, and water use efficiency? Trends in Plant Science, 27, pp. 166-179. (doi: 10.1016/j.tplants.2021.08.010)

Nakasone, M. A., Majorek, K. A., Gabrielsen, M., Sibbet, G. J., Smith, B. O., Huang, D. T. (2022) Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension. Nature Chemical Biology, 18, pp. 422-431. (doi: 10.1038/s41589-021-00952-x)

Neckebroeck, A., Kelly, S. M., Smith, B. O., Clark, J. S. (2022) Synthesis of the prototypical cyclopropyl dipeptide mimic and evaluation of its turn-inducing capability. Journal of Organic Chemistry, 87, pp. 258-270. (doi: 10.1021/acs.joc.1c02344)

Yukihira, N., Uragami, C., Horiuchi, K., Kosumi, D., Gardiner, A. T., Cogdell, R. J., Hashimoto, H. (2022) Intramolecular charge-transfer enhances energy transfer efficiency in carotenoid-reconstituted light-harvesting 1 complex of purple photosynthetic bacteria. Communications Chemistry, 5, (doi: 10.1038/s42004-022-00749-6)

Zhdanov, O., Blatt, M. R., Zare-Behtash, H., Busse, A. (2022) Unidirectional versus bidirectional brushing: simulating wind influence on Arabidopsis thaliana. Quantitative Plant Biology, 3, (doi: 10.1017/qpb.2021.14)


Tokatlidis, K., Eaglesfield, R. (2021) Targeting and insertion of membrane proteins in mitochondria. Frontiers in Cell and Developmental Biology, 9, (doi: 10.3389/fcell.2021.803205)

Blatt, M. (2021) Ae fond fareweel. Plant Physiology, 187, pp. 2341-2343. (doi: 10.1093/plphys/kiab467)

Zioutopoulou, A., Patitaki, E., Xu, T., Kaiserli, E. (2021) The epigenetic mechanisms underlying thermomorphogenesis and heat stress responses in Arabidopsis. Plants, 10, (doi: 10.3390/plants10112439)

Sullivan, S., Waksman, T., Paliogianni, D., Henderson, L., Lütkemeyer, M., Suetsugu, N., Christie, J. M. (2021) Regulation of plant phototropic growth by NPH3/RPT2-like substrate phosphorylation and 14-3-3 binding. Nature Communications, 12, (doi: 10.1038/s41467-021-26333-5)

Prabhakar, A. T., James, C. D., Das, D., Otoa, R., Day, M., Burgner, J., Fontan, C. T., Wang, X., Wieland, A., Donaldson, M. M., Bristol, M. L., Li, R., Oliver, A. W., Pearl, L. H., Smith, B. O., Glass, S., Morgan, I. M. (2021) CK2 phosphorylation of human papillomavirus 16 E2 on serine 23 promotes interaction with TopBP1 and is critical for E2 interaction with mitotic chromatin and the viral life cycle. mBio, 12, (doi: 10.1128/mbio.01163-21)

Jezek, M., Silva-Alvim, F. A.L., Hills, A., Donald, N., Ishka, M. R., Shadbolt, J., He, B., Lawson, T., Harper, J. F., Wang, Y., Lew, V. L., Blatt, M. R. (2021) Guard cell endomembrane Ca2+-ATPases underpin a ‘carbon memory’ of photosynthetic assimilation that impacts on water-use efficiency. Nature Plants, 7, pp. 1301-1313. (doi: 10.1038/s41477-021-00966-2)

Buist, H. K., Luchowska-Stańska, U., van Basten, B., Valli, J., Smith, B. O., Baillie, G. S., Rickman, C., Ricketts, B., Davidson, A., Hannam, R., Sunderland, J., Yarwood, S. J. (2021) Identification and characterization of an affimer affinity reagent for the detection of the cAMP sensor, EPAC1. Cells, 10, (doi: 10.3390/cells10092307)

Geldon, S., Fernandez-Vizarra, E., Tokatlidis, K. (2021) Redox-mediated regulation of mitochondrial biogenesis, dynamics and respiratory chain assembly in yeast and human cells. Frontiers in Cell and Developmental Biology, 9, (doi: 10.3389/fcell.2021.720656)

Kakoulidou, I., Avramidou, E. V., Baránek, M., Brunel-Muguet, S., Farrona, S., Johannes, F., Kaiserli, E., Lieberman-Lazarovich, M., Martinelli, F., Mladenov, V., Testillano, P. S., Vassileva, V., Maury, S. (2021) Epigenetics for crop improvement in times of global change. Biology, 10, (doi: 10.3390/biology10080766)

Kim, J., Nguyen-Phan, T. C., Gardiner, A. T., Cogdell, R. J., Scholes, G. D., Cho, M. (2021) Low-frequency vibronic mixing modulates the excitation energy flow in bacterial light-harvesting complex II. Journal of Physical Chemistry Letters, 12, pp. 6292-6298. (doi: 10.1021/acs.jpclett.1c01782)

Mladenov, V., Fotopoulos, V., Kaiserli, E., Karalija, E., Maury, S., Baranek, M., Segal, N., Testillano, P. S., Vassileva, V., Pinto, G., Nagel, M., Hoenicka, H., Miladinović, D., Gallusci, P., Vergata, C., Kapazoglou, A., Abraham, E., Tani, E., Gerakari, M., Sarri, E., Avramidou, E., Gašparović, M., Martinelli, F. (2021) Deciphering the epigenetic alphabet involved in transgenerational stress memory in crops. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22137118)

Morgan, D. C., Morris, C., Mahindra, A., Blair, C. M., Tejeda, G., Herbert, I., Turnbull, M. L., Lieber, G., Willett, B. J., Logan, N., Smith, B., Tobin, A. B., Bhella, D., Baillie, G. S., Jamieson, A. G. (2021) Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalisation. Peptide Science, 113, (doi: 10.1002/pep2.24217)

Diamantopoulou, C., Christoforou, E., Dominoni, D. M., Kaiserli, E., Czyzewski, J., Mirzai, N., Spatharis, S. (2021) Wavelength-dependent effects of artificial light at night on phytoplankton growth and community structure. Proceedings of the Royal Society of London Series B: Biological Sciences, 288, (doi: 10.1098/rspb.2021.0525)

Gundogdu, M., Tadayon, R., Salzano, G., Shaw, G. S., Walden, H. (2021) A mechanistic review of Parkin activation. Biochimica et Biophysica Acta. General Subjects, 1865, (doi: 10.1016/j.bbagen.2021.129894)

Morris, E. P., da Fonseca, P. C.A. (2021) How to build a proteasome. Nature Structural and Molecular Biology, 28, pp. 409-410. (doi: 10.1038/s41594-021-00592-8)

van Beek, L., McClay, É., Patel, S., Schimpl, M., Spagnolo, L., Maia de Oliveira, T. (2021) PARP power: a structural perspective on PARP1, PARP2, and PARP3 in DNA damage repair and nucleosome remodelling. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22105112)

Klejchova, M., Silva-Alvim, F. A.L., Blatt, M. R., Alvim, J. C. (2021) Membrane voltage as a dynamic platform for spatio-temporal signalling, physiological and developmental regulation. Plant Physiology, 185, pp. 1523-1541. (doi: 10.1093/plphys/kiab032)

Rennie, M. L., Arkinson, C., Chaugule, V. K., Toth, R., Walden, H. (2021) Structural basis of FANCD2 deubiquitination by USP1-UAF1. Nature Structural and Molecular Biology, 28, pp. 356-364. (doi: 10.1038/s41594-021-00576-8)

Rolczynski, B. S., Yeh, S.-H., Navotnaya, P., Lloyd, L. T., Ginzburg, A. R., Zheng, H., Allodi, M. A., Otto, J. P., Ashraf, K., Gardiner, A. T., Cogdell, R. J., Kais, S., Engel, G. S. (2021) Time-domain line-shape analysis from 2D spectroscopy to precisely determine Hamiltonian parameters for a photosynthetic complex. Journal of Physical Chemistry B, 125, pp. 2812-2820. (doi: 10.1021/acs.jpcb.0c08012)

Christie, J. M., Zurbriggen, M. D. (2021) Optogenetics in plants. New Phytologist, 229, pp. 3108-3115. (doi: 10.1111/nph.17008)

Perrella, G., Zioutopoulou, A., Hamilton, A., Kaiserli, E. (2021) Photobody detection using immunofluorescence and super-resolution imaging in Arabidopsis. Humana

Edwards, R., Eaglesfield, R., Tokatlidis, K. (2021) The mitochondrial intermembrane space: the most constricted mitochondrial sub-compartment with the largest variety of protein import pathways. Open Biology, 11, (doi: 10.1098/rsob.210002)

Zhdanov, O., Blatt, M. R., Zare-Behtash, H., Busse, A. (2021) Wind-evoked anemotropism affects the morphology and mechanical properties of Arabidopsis. Journal of Experimental Botany, 72, pp. 1906-1918. (doi: 10.1093/jxb/eraa541)

Gardiner, A. T., Naydenova, K., Castro-Hartmann, P., Nguyen-Phan, C. T., Russo, C. J., Sader, K., Hunter, C. N., Cogdell, R. J., Qian, P. (2021) The 2.4 Å cryo-EM structure of a heptameric light-harvesting 2 complex reveals two carotenoid energy transfer pathways. Science Advances, 7, (doi: 10.1126/sciadv.abe4650)

Zhang, B., Xia, L., Zhang, Y., Wang, H., Karnik, R. (2021) Tri-SUS: a yeast split-ubiquitin assay to examine protein interactions governed by a third binding partner. Plant Physiology, 185, pp. 285-289. (doi: 10.1093/plphys/kiaa039)

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Maćkowski, S., Czechowski, N., Ashraf, K. U., Szalkowski, M., Lokstein, H., Cogdell, R. J., Kowalska, D. (2016) Origin of bimodal fluorescence enhancement factors of Chlorobaculum tepidumreaction centers on silver island films. FEBS Letters, 590, pp. 2558-2565. (doi: 10.1002/1873-3468.12292)

Kalef-Ezra, E., Kotzamani, D., Zaganas, I., Katrakili, N., Plaitakis, A., Tokatlidis, K. (2016) Import of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence. Biochemical Journal, 473, pp. 2813-2829. (doi: 10.1042/BCJ20160535)

Findlay, K. M.W., Jenkins, G. I. (2016) Regulation of UVR8 photoreceptor dimer/monomer photo-equilibrium in Arabidopsis plants grown under photoperiodic conditions. Plant Cell and Environment, 39, pp. 1706-1714. (doi: 10.1111/pce.12724)

Vance, S. J., Desai, V., Smith, B. O., Kennedy, M. W., Cooper, A. (2016) Aqueous solubilization of C60 fullerene by natural protein surfactants, latherin and ranaspumin-2. Biophysical Chemistry, 214-15, pp. 27-32. (doi: 10.1016/j.bpc.2016.05.003)

Chatzi, A., Manganas, P., Tokatlidis, K. (2016) Oxidative folding in the mitochondrial intermembrane space: a regulated process important for cell physiology and disease. Biochimica et Biophysica Acta: Molecular Cell Research, 1863, pp. 1298-1306. (doi: 10.1016/j.bbamcr.2016.03.023)

Ashraf, K. U., Josts, I., Mosbahi, K., Kelly, S. M., Byron, O., Smith, B. O., Walker, D. (2016) The potassium binding protein Kbp is a cytoplasmic potassium sensor. Structure, 24, pp. 741-749. (doi: 10.1016/j.str.2016.03.017)

Gawthorne, J. A., Audry, L., McQuitty, C., Dean, P., Christie, J. M., Enninga, J., Roe, A. J. (2016) Visualizing translocation and localization of bacterial type III effector proteins using a genetically encoded reporter system. Applied and Environmental Microbiology, 82, pp. 2700-2708. (doi: 10.1128/AEM.03418-15)

Buckley, A. M., Jukes, C., Candlish, D., Irvine, J. J., Spencer, J., Fagan, R. P., Roe, A. J., Christie, J., Fairweather, N. F., Douce, G. R. (2016) Lighting up Clostridium Difficile: reporting gene expression using fluorescent Lov domains. Scientific Reports, 6, (doi: 10.1038/srep23463)

Malý, P., Gruber, J. M., Cogdell, R. J., Mančal, T., van Grondelle, R. (2016) Ultrafast energy relaxation in single light-harvesting complexes. Proceedings of the National Academy of Sciences of the United States of America, 113, pp. 2934-2939. (doi: 10.1073/pnas.1522265113)

Sullivan, S., Hart, J. E., Rasch, P., Walker, C., Christie, J. (2016) Phytochrome A mediates blue-light enhancement of second-positive phototropism in Arabidopsis. Frontiers in Plant Science, 7, (doi: 10.3389/fpls.2016.00290)

Jones, D. D., Beal, J., Haddock-Angelli, T., Gershater, M., de Mora, K., Lizarazo, M., Hollenhorst, J., Rettberg, R., iGEM Interlab Study Contributors, (2016) Reproducibility of fluorescent expression from engineered biological constructs in E. coli. PLoS ONE, 11, (doi: 10.1371/journal.pone.0150182)

Modjtahedi, N., Tokatlidis, K., Dessen, P., Kroemer, G. (2016) Mitochondrial proteins containing coiled-coil-helix-coiled-coil-helix (CHCH) domains in health and disease. Trends in Biochemical Sciences, 41, pp. 245-260. (doi: 10.1016/j.tibs.2015.12.004)

Chen, Z.-H., Wang, Y., Wang, J.-W., Babla, M., Zhao, C., Garcia-Mata, C., Sani, E., Differ, C., Mak, M., Hills, A., Amtmann, A., Blatt, M. R. (2016) Nitrate reductase mutation alters potassium nutrition as well as nitric oxide-mediated control of guard cell ion channels in Arabidopsis. New Phytologist, 209, pp. 1456-1469. (doi: 10.1111/nph.13714)

Morreale, F. E., Walden, H. (2016) Types of ubiquitin ligases. Cell, 165, pp. 248-248.e1. (doi: 10.1016/j.cell.2016.03.003)

Li, H., O’Donoghue, A. J., van der Linden, W. A., Xie, S. C., Yoo, E., Foe, I. T., Tilley, L., Craik, C. S., da Fonseca, P. C.A., Bogyo, M. (2016) Structure- and function-based design of Plasmodium-selective proteasome inhibitors. Nature, 530, pp. 233-236. (doi: 10.1038/nature16936)

Ferretti, M., Hendrikx, R., Romero, E., Southall, J., Cogdell, R. J., Novoderezhkin, V. I., Scholes, G. D., van Grondelle, R. (2016) Dark states in the light-harvesting complex 2 revealed by two-dimensional electronic spectroscopy. Scientific Reports, 6, (doi: 10.1038/srep20834)

Blatt, M. R. (2016) Plant physiology: redefining the enigma of metabolism in stomatal movement. Current Biology, 26, pp. R107-R109. (doi: 10.1016/j.cub.2015.12.025)

Chaugule, V. K., Walden, H. (2016) Specificity and disease in the ubiquitin system. Biochemical Society Transactions, 44, pp. 212-227. (doi: 10.1042/BST20150209)

Magdaong, N. M., LaFountain, A. M., Hacking, K., Niedzwiedzki, D. M., Gibson, G. N., Cogdell, R., Frank, H. A. (2016) Spectral heterogeneity and carotenoid-to-bacteriochlorophyll energy transfer in LH2 light-harvesting complexes from Allochromatium vinosum. Photosynthesis Research, 127, pp. 171-187. (doi: 10.1007/s11120-015-0165-2)

Henry, S. L., Withers, J. M., Singh, I., Cooper, J. M., Clark, A. W., Burley, G. A., Cogdell, R. J. (2016) DNA-directed spatial assembly of photosynthetic light-harvesting proteins. Organic and Biomolecular Chemistry, 14, pp. 1359-1362. (doi: 10.1039/c5ob02351c)

Pokhilko, A., Zhao, J., Stark, W. M., Colloms, S. D., Ebenhöh, O. (2016) A simplified mathematical model of directional DNA site-specific recombination by serine integrases. Journal of the Royal Society: Interface, 14, (doi: 10.1098/rsif.2016.0618)

Connolly, J. P. R., Gabrielsen, M., Goldstone, R. J., Grinter, R., Wang, D., Cogdell, R. J., Walker, D., Smith, D. G. E., Roe, A. J. (2016) A highly conserved bacterial d-serine uptake system links host metabolism and virulence. PLoS Pathogens, 12, (doi: 10.1371/journal.ppat.1005359)

Minguet-Parramona, C., Wang, Y., Hills, A., Vialet-Chabrand, S., Griffiths, H., Rogers, S., Lawson, T., Lew, V. L., Blatt, M. R. (2016) An optimal frequency in Ca2+ oscillations for stomatal closure is an emergent property of ion transport in guard cells. Plant Physiology, 170, pp. 33-42. (doi: 10.1104/pp.15.01607)

Sullivan, S., Petersen, J., Blackwood, L., Papanatsiou, M., Christie, J. M. (2016) Functional characterisation of Ostreococcus tauri phototropin. New Phytologist, 209, pp. 612-623. (doi: 10.1111/nph.13640)

Hashimoto, H., Uragami, C., Cogdell, R. J. (2016) Carotenoids and Photosynthesis. Springer International Publishing

Kosumi, D., Horibe, T., Sugisaki, M., Cogdell, R. J., Hashimoto, H. (2016) Photoprotection mechanism of light-harvesting antenna complex from purple bacteria. Journal of Physical Chemistry B, 120, pp. 951-956. (doi: 10.1021/acs.jpcb.6b00121)

Wientjes, E., Renger, J., Cogdell, R., van Hulst, N. F. (2016) Pushing the photon limit: nanoantennas increase maximal photon stream and total photon number. Journal of Physical Chemistry Letters, 7, pp. 1604-1609. (doi: 10.1021/acs.jpclett.6b00491)

Merrick, C.A., Wardrope, C., Paget, J.E., Colloms, S.D., Rosser, S.J. (2016) Rapid optimization of engineered metabolic pathways with serine integrase recombinational assembly (SIRA) Elsevier

Velanis, C. N., Herzyk, P., Jenkins, G. I. (2016) Regulation of transcription by the Arabidopsis UVR8 photoreceptor involves a specific histone modification. Plant Molecular Biology, 92, pp. 425-443. (doi: 10.1007/s11103-016-0522-3)

Miki, T., Buckup, T., Krause, M. S., Southall, J., Cogdell, R. J., Motzkus, M. (2016) Vibronic coupling in the excited-states of carotenoids. Physical Chemistry Chemical Physics, 18, pp. 11443-11453. (doi: 10.1039/C5CP07542D)


Kita, S., Fujii, R., Cogdell, R. J., Hashimoto, H. (2015) Characterization of fucoxanthin aggregates in mesopores of silica gel: electronic absorption and circular dichroism spectroscopies. Journal of Photochemistry and Photobiology A: Chemistry, 313, pp. 3-8. (doi: 10.1016/j.jphotochem.2015.05.009)

Hashimoto, H., Sugai, Y., Uragami, C., Gardiner, A. T., Cogdell, R. (2015) Natural and artificial light-harvesting systems utilizing the functions of carotenoids. Journal of Photochemistry and Photobiology C: Photochemistry Reviews, 25, pp. 46-70. (doi: 10.1016/j.jphotochemrev.2015.07.004)

Uragami, C., Sugai, Y., Hanjo, K., Sumino, A., Fujii, R., Nishioka, T., Kinoshita, I., Dewa, T., Nango, M., Gardiner, A. T., Cogdell, R. J., Hashimoto, H. (2015) Observation of hybrid artificial photosynthetic membranes using peripheral and core antennae from two different species of photosynthetic bacteria by AFM and fluorescence micro-spectroscopy. Journal of Photochemistry and Photobiology A: Chemistry, 313, pp. 60-71. (doi: 10.1016/j.jphotochem.2015.06.009)

Kaiserli, E., Páldi, K., O’Donnell, L., Batalov, O., Pedmale, U. V., Nusinow, D. A., Kay, S. A., Chory, J. (2015) Integration of light and photoperiodic signaling in transcriptional nuclear foci. Developmental Cell, 35, pp. 311-321. (doi: 10.1016/j.devcel.2015.10.008)

Schörner, M., Beyer, S. R., Southall, J., Cogdell, R. J., Köhler, J. (2015) Conformational memory of a protein revealed by single-molecule spectroscopy. Journal of Physical Chemistry B, 119, pp. 13964-13970. (doi: 10.1021/acs.jpcb.5b07494)

Schörner, M., Beyer, S. R., Southall, J., Cogdell, R., Köhler, J. (2015) Multi-level, multi time-scale fluorescence intermittency of photosynthetic LH2 complexes: a precursor of non-photochemical quenching? Journal of Physical Chemistry B, 119, pp. 13958-13963. (doi: 10.1021/acs.jpcb.5b06979)

Rey, B. M.F., Ibáñez, S. M., Gabrielsen, M., Franchini, G. R., Roe, A. J., Griffiths, K., Zhan, B., Cooper, A., Kennedy, M. W., Córsico, B., Smith, B. O. (2015) Diversity in the structures and ligand binding sites of nematode fatty acid and retinol binding proteins revealed by Na-FAR-1 from Necator americanus. Biochemical Journal, 471, pp. 403-414. (doi: 10.1042/BJ20150068)

Thomson, R., Smith, B. O. (2015) Solution structure of human MBD1 CXXC1. Journal of Biomolecular NMR, 63, pp. 309-314. (doi: 10.1007/s10858-015-9986-8)

Kumar, A., Aguirre, J. D., Condos, T. E.C., Martinez-Torres, R. J., Chaugule, V. K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D. E., Barber, K. R., Shaw, G. S., Walden, H. (2015) Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. EMBO Journal, 34, pp. 2506-2521. (doi: 10.15252/embj.201592337)

Cogdell, R. J., Gardiner, A. T. (2015) Activated OCP unlocks nonphotochemical quenching in cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America, 112, pp. 12547-12548. (doi: 10.1073/pnas.1517477112)

Alles, J., Hasler, D., Kazmi, S. M. A., Tesson, M., Hamilton, A., Schlegel, L., Marx, S., Eichner, N., Reinhardt, R., Meister, G., Wilson, J. B., Grässer, F. A. (2015) Epstein-Barr virus EBER transcripts affect miRNA-mediated regulation of specific targets and are processed to small RNA species. Non-Coding RNA, 1, pp. 170-191. (doi: 10.3390/ncrna1030170)

Bowyer, J., Zhao, J., Rosser, S., Colloms, S., Bates, D. (2015) Development and experimental validation of a mechanistic model of in vitro DNA recombination. (doi: 10.1109/EMBC.2015.7318519)

Joshi, A., Grinter, R., Josts, I., Chen, S., Wojdyla, J., Lowe, E., Kaminska, R., Sharp, C., McCaughey, L., Roszak, A., Cogdell, R., Byron, O., Walker, D., Kleanthous, C. (2015) Structures of the ultra-high-affinity protein–protein complexes of pyocins S2 and AP41 and their cognate immunity proteins from pseudomonas aeruginosa. Journal of Molecular Biology, 427, pp. 2852-2866. (doi: 10.1016/j.jmb.2015.07.014)

Miles, J. A., Frost, M. G., Carroll, E., Rowe, M. L., Howard, M. J., Sidhu, A., Chaugule, V. K., Alpi, A. F., Walden, H. (2015) The Fanconi Anemia DNA repair pathway is regulated by an interaction between ubiquitin and the E2-like fold domain of FANCL. Journal of Biological Chemistry, 290, pp. 20995-21006. (doi: 10.1074/jbc.M115.675835)

Kazlauskaite, A., Martinez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M.F., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H., Muqit, M. M.K. (2015) Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. EMBO Reports, 16, pp. 939-954. (doi: 10.15252/embr.201540352)

Grefen, C., Karnik, R., Larson, E., Lefoulon, C., Wang, Y., Waghmare, S., Zhang, B., Hills, A., Blatt, M. R. (2015) A vesicle-trafficking protein commandeers Kv channel voltage sensors for voltage-dependent secretion. Nature Plants, 1, (doi: 10.1038/nplants.2015.108)

Buckley, A. M., Petersen, J., Roe, A. J., Douce, G. R., Christie, J. M. (2015) LOV-based reporters for fluorescence imaging. Current Opinion in Chemical Biology, 27, pp. 39-45. (doi: 10.1016/j.cbpa.2015.05.011)

da Fonseca, P. C.A., Morris, E. P. (2015) Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core. Nature Communications, 6, (doi: 10.1038/ncomms8573)

Fyfe, C.D., Grinter, R., Josts, I., Mosbahi, K., Roszak, A.W., Cogdell, R.J., Wall, D.M., Burchmore, R.J.S., Byron, O., Walker, D. (2015) Structure of protease-cleaved escherichia coliα-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Acta Crystallographica. Section D: Biological Crystallography, 71, pp. 1478-1486. (doi: 10.1107/s1399004715008548)

Hangen, E. et al. (2015) Interaction between AIF and CHCHD4 regulates respiratory chain biogenesis. Molecular Cell, 58, pp. 1001-1014. (doi: 10.1016/j.molcel.2015.04.020)

Gao, X., Wilson, J.B. (2015) LMP1: Chronic Inflammation and Carcinogenesis.

Zhang, B., Karnik, R., Wang, Y., Wallmeroth, N., Blatt, M. R., Grefen, C. (2015) The arabidopsis R-SNARE VAMP721 interacts with KAT1 and KC1 K+ channels to moderate K+ current at the plasma membrane. Plant Cell, 27, pp. 1697-1717. (doi: 10.1105/tpc.15.00305)

Papanatsiou, M., Scuffi, D., Blatt, M. R., Garia-Mata, C. (2015) Hydrogen sulphide regulates inward-rectifying K+ channels in conjunction with stomatal closure. Plant Physiology, 168, pp. 29-35. (doi: 10.1104/pp.114.256057)

Preuten, T., Blackwood, L., Christie, J. M., Fankhauser, C. (2015) Lipid anchoring of Arabidopsis phototropin 1 to assess the functional significance of receptor internalization: should I stay or should I go? New Phytologist, 206, pp. 1038-1050. (doi: 10.1111/nph.13299)

Fankhauser, C., Christie, J. M. (2015) Plant Phototropic Growth. Current Biology, 25, pp. R384-R389. (doi: 10.1016/j.cub.2015.03.020)

Parnell, E., Smith, B. O., Yarwood, S. J. (2015) The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal. Cellular Signalling, 27, pp. 989-996. (doi: 10.1016/j.cellsig.2015.02.009)

Buetow, L., Gabrielsen, M., Anthony, N. G., Dou, H., Patel, A., Aitkenhead, H., Sibbet, G. J., Smith, B. O., Huang, D. T. (2015) Activation of a primed RING E3-E2–ubiquitin complex by non-covalent ubiquitin. Molecular Cell, 58, pp. 297-310. (doi: 10.1016/j.molcel.2015.02.017)

Connolly, J. P.R., Goldstone, R. J., Burgess, K., Cogdell, R. J., Beatson, S. A., Vollmer, W., Smith, D. G.E., Roe, A. (2015) The host metabolite D-serine contributes to bacterial niche specificity through gene selection. ISME Journal, 9, pp. 1039-1051. (doi: 10.1038/ismej.2014.242)

Kaiserli, E., Chory, J. (2015) The role of phytochromes in triggering plant developmental transitions. John Wiley and Sons Ltd

Karnik, R., Zhang, B., Waghmare, S., Aderhold, C., Grefen, C., Blatt, M. R. (2015) Binding of SEC11 indicates its role in SNARE recycling after vesicle fusion and identifies two pathways for vesicular traffic to the plasma membrane. Plant Cell, 27, pp. 675-694. (doi: 10.1105/tpc.114.134429)

Shigemitsu, Y., Ikeya, T., Yamamoto, A., Tsuchie, Y., Mishima, M., Smith, B. O., Güntert, P., Ito, Y. (2015) Evaluation of the reliability of the maximum entropy method for reconstructing 3D and 4D NOESY-type NMR spectra of proteins. Biochemical and Biophysical Research Communications, 457, pp. 200-205. (doi: 10.1016/j.bbrc.2014.12.088)

Heilmann, M., Christie, J. M., Kennis, J. T.M., Jenkins, G. I., Mathes, T. (2015) Photoinduced transformation of UVR8 monitored by vibrational and fluorescence spectroscopy. Photochemical and Photobiological Sciences, 14, pp. 252-257. (doi: 10.1039/c4pp00246f)

Franchini, G. R., Pórfido, J. L., Ibáñez Shimabukuro, M., Rey Burusco, M. F., Bélgamo, J. A., Smith, B. O., Kennedy, M. W., Córsico, B. (2015) The unusual lipid binding proteins of parasitic helminths and their potential roles in parasitism and as therapeutic targets. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 93, pp. 31-36. (doi: 10.1016/j.plefa.2014.08.003)

Cannone, G., Xu, Y., Beattie, T. R., Bell, S. D., Spagnolo, L. (2015) The architecture of an Okazaki fragment-processing holoenzyme from the archaeon Sulfolobus solfataricus. Biochemical Journal, 465, pp. 239-245. (doi: 10.1042/BJ20141120)

Löhner, A., Carey, A.-M., Hacking, K., Picken, N., Kelly, S., Cogdell, R., Köhler, J. (2015) The origin of the split B800 absorption peak in the LH2 complexes from Allochromatium vinosum. Photosynthesis Research, 123, pp. 23-31. (doi: 10.1007/s11120-014-0036-2)

Cosentino, C., Alberio, L., Gazzarrini, S., Aquila, M., Romano, E., Cermenati, S., Zuccolini, P., Petersen, J., Beltrame, M., Van Etten, J. L., Christie, J., Thiel, G., Moroni, A. (2015) Engineering of a light-gated potassium channel. Science, 348, pp. 707-710. (doi: 10.1126/science.aaa2787)

Christie, J. M., Blackwood, L., Petersen, J., Sullivan, S. (2015) Plant flavoprotein photoreceptors. Plant and Cell Physiology, 56, pp. 401-413. (doi: 10.1093/pcp/pcu196)

Mathes, T., Heilmann, M., Pandit, A., Zhu, J., Ravensbergen, J., Kloz, M., Fu, Y., Smith, B.O., Christie, J.M., Jenkins, G.I., Kennis, J.T.M. (2015) Proton-coupled electron transfer constitutes the photoactivation mechanism of the plant photoreceptor UVR8. Journal of the American Chemical Society, 137, pp. 8113-8120. (doi: 10.1021/jacs.5b01177)

Ulm, R., Jenkins, G. (2015) Q&A: How do plants sense and respond to UV-B radiation? BMC Biology, 13, (doi: 10.1186/s12915-015-0156-y)

Miyamori, T., Nakasone, Y., Hitomi, K., Christie, J. M., Getzoff, E. D., Terazima, M. (2015) Reaction dynamics of the UV-B photosensor UVR8. Photochemical and Photobiological Sciences, 14, pp. 995-1004. (doi: 10.1039/c5pp00012b)

Mordas, A., Tokatlidis, K. (2015) The MIA pathway: a key regulator of mitochondrial oxidative protein folding and biogenesis. Accounts of Chemical Research, 48, pp. 2191-2199. (doi: 10.1021/acs.accounts.5b00150)

Ji, H., Wang, Y., Cloix, C., Li, K., Jenkins, G. I., Wang, S., Shang, Z., Shi, Y., Yang, S., Li, X. (2015) The arabidopsis RCC1 family protein TCF1 regulates freezing tolerance and cold acclimation through modulating lignin biosynthesis. PLoS Genetics, 11, (doi: 10.1371/journal.pgen.1005471)

Beyer, S. R., Müller, L., Southall, J., Cogdell, R. J., Ullmann, G. M., Köhler, J. (2015) The open, the closed, and the empty: time-resolved fluorescence spectroscopy and computational analysis of RC-LH1 complexes from Rhodopseudomonas palustris. Journal of Physical Chemistry B, 119, pp. 1362-1373. (doi: 10.1021/jp510822k)

Dominguez, P.N., Himmelstoss, M., Michelmann, J., Lehner, F., Gardiner, A., Cogdell, R.J., Zinth, W. (2015) The primary photosynthetic energy conversion in bacterial reaction centers—stepwise electron transfer and the effect of elevated exposure levels. Springer

Singh, V.P., Westberg, M., Wang, C., Dahlberg, P.D., Gellen, T., Gardiner, A.T., Cogdell, R.J., Engel, G.S. (2015) Towards quantification of vibronic coupling in photosynthetic antenna complexes. Journal of Chemical Physics, 142, pp. 212446. (doi: 10.1063/1.4921324)

Maiuri, M., Lüer, L., Henry, S., Carey, A.-M., Cogdell, R.J., Cerullo, G., Polli, D. (2015) Ultrafast energy flow and equilibration dynamics in photosynthetic light-harvesting complexes. Springer International Publishing

Perlík, V., Seibt, J., Cranston, L. J., Cogdell, R. J., Lincoln, C. N., Savolainen, J., Šanda, F., Mančal, T., Hauer, J. (2015) Vibronic coupling explains the ultrafast carotenoid-to-bacteriochlorophyll energy transfer in natural and artificial light harvesters. Journal of Chemical Physics, 142, (doi: 10.1063/1.4919548)

Postgraduate research students

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Our research aim is to answer fundamental questions related to the structure and function of proteins involved in important biochemical processes. Major topics on this theme include:

  • how membrane proteins form structure during biogenesis
  • how proteins are trafficked to and from the cell membrane in response to insulin stimulation
  • how protein folding is influenced by redox phenomena
  • how protein homeostasis is regulated by ubiquitin

There is a strong emphasis on the determination of protein structures using X-ray crystallography, NMR and cryo-EM. Targets of these studies include photosynthetic light harvesting complexes, plant photoreceptors and large multimeric complexes involved in RNA and DNA metabolism. These structural studies are complemented by function studies aimed at elucidating molecular mechanisms of action. Our work is supported by expertise from the Structural Biology and Biophysical Characterisation Facility and the Scottish Centre for Macromolecular Imaging. Multi-omic systems approaches, including next-generation sequencing are provided through Glasgow Polyomics.

Examples of some of the structures that we have determined are illustrated below: