Molecular Genetics

The University of Glasgow has a longstanding reputation as a centre for world-class research and teaching in genetics.

Staff

Publications

2024

Yaduma, W. G., Rezig, I. M., Gould, G. W., McInerny, C. J. (2024) Phosphorylation of anillin/Mid1p in fission yeast regulates its sub-cellular distribution and is required for cytokinesis. Cell Cycle,

Liu, W., Jenkins, G. (2024) Recent advances in UV-B signalling: Interaction of proteins with the UVR8 photoreceptor. Journal of Experimental Botany, (doi: 10.1093/jxb/erae132)

Ruiz de Sabando, A., Ciosi, M., Galbete, A., Cumming, S. A., Spanish HD Collaborative Group, , Monckton, D. G., Ramos-Arroyo, M. A. (2024) Somatic CAG repeat instability in intermediate alleles of the HTT gene and its potential association with a clinical phenotype. European Journal of Human Genetics, (doi: 10.1038/s41431-024-01546-6)

Nguyen, T.-H., Blatt, M. R. (2024) Surrounded by luxury: the necessities of subsidiary cells. Plant, Cell and Environment, (doi: 10.1111/pce.14872)

Kulkarni, J., Sahoo, S. A., Herzyk, P., Barvkar, V. T., Kumar, S. A., Ravichandran, J., Samal, A., Amtmann, A., Borde, M., Suprasanna, P., Srivastava, A. K. (2024) Early-responsive molecular signatures associated with halophytic adaptation in Sesuvium portulacastrum (L.) Plant, Cell and Environment, 47, pp. 961-975. (doi: 10.1111/pce.14767)

Adamson, W. E., Noyes, H., Johnson, P., Cooper, A., Monckton, D. G., Ogunsola, J., Beckett-Hill, G., Sullivan, M., Mark, P., Parekh, R. S., MacLeod, A. (2024) Phenome-wide analysis reveals epistatic associations between APOL1 variants and chronic kidney disease and multiple other disorders. EBioMedicine, 101, (doi: 10.1016/j.ebiom.2024.105000)

Sinton, M. C., Chandrasegaran, P. R.G., Capewell, P., Cooper, A., Girard, A., Ogunsola, J., Perona-Wright, G., Ngoyi, D. M., Kuispond, N., Bucheton, B., Camara, M., Kajimura, S., Bénézech, C., Mabbott, N. A., MacLeod, A., Quintana, J. F. (2024) Publisher Correction: IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection. Nature Communications, 15, (doi: 10.1038/s41467-024-46299-4)

Rezig, I. M., Yaduma, W. G., McInerny, C. J. (2024) Processes controlling the contractile ring during cytokinesis in fission yeast including the role of ESCRT proteins. Journal of Fungi, 10, (doi: 10.3390/jof10020154)

Liu, W., Giuriani, G., Havlikova, A., Li, D., Lamont, D. J., Neugart, S., Velanis, C. N., Petersen, J., Hoecker, U., Christie, J. M., Jenkins, G. (2024) Phosphorylation of Arabidopsis UVR8 photoreceptor modulates protein interactions and responses to UV-B radiation. Nature Communications, 15, (doi: 10.1038/s41467-024-45575-7)

Busch, F. A., Ainsworth, E. A., Amtmann, A., Cavanagh, A. P., Driever, S. M., Ferguson, J. N., Kromdijk, J., Lawson, T., Leakey, A. D. B., Matthews, J. S. A., Meacham‐Hensold, K., Vath, R. L., Vialet‐Chabrand, S., Walker, B. J., Papanatsiou, M. (2024) A guide to photosynthetic gas exchange measurements: fundamental principles, best practice and potential pitfalls. Plant, Cell and Environment, (doi: 10.1111/pce.14815)

Baena, G., Xia, L., Waghmare, S., Yu, Z., Guo, Y., Blatt, M. R., Zhang, B., Karnik, R. (2024) Arabidopsis SNARE SYP132 impacts on PIP2;1 trafficking and function in salinity stress. Plant Journal, (doi: 10.1111/tpj.16649)

Blatt, M. R. (2024) A charged existence: a century of transmembrane ion transport in plants. Plant Physiology, (doi: 10.1093/plphys/kiad630)

Shahzad, Z., Tournaire‐Roux, C., Canut, M., Adamo, M., Roeder, J., Verdoucq, L., Martinière, A., Amtmann, A., Santoni, V., Grill, E., Loudet, O., Maurel, C. (2024) Protein kinase SnRK2. 4 is a key regulator of aquaporins and root hydraulics in Arabidopsis. Plant Journal, 117, pp. 264-279. (doi: 10.1111/tpj.16494)

2023

Silva-Alvim, F. A.L., Alvim, J. C., Harvey, A., Blatt, M. R. (2023) Speedy stomata of a C4 plant correlate with enhanced K+ channel gating. Plant, Cell and Environment, (doi: 10.1111/pce.14775)

Zhang, J., Nirmala, J., Chen, S., Jost, M., Steuernagel, B., Karafiatova, M., Hewitt, T., Li, H., Edae, E., Sharma, K., Hoxha, S., Bhatt, D., Antoniou Kourounioti, R. L., Dodds, P., Wulff, B. B.H., Dolezel, J., Ayliffe, M., Hiebert, C., McIntosh, R., Dubcovsky, J., Zhang, P., Rouse, M. N., Lagudah, E. (2023) Single amino acid change alters specificity of the multi-allelic wheat stem rust resistance locus SR9. Nature Communications, 14, (doi: 10.1038/s41467-023-42747-9)

Gould, E. et al. (2023) Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology. EcoEvoRxiv, (doi: 10.32942/X2GG62)

Sinton, M. C., Chandrasegaran, P. R.G., Capewell, P., Cooper, A., Girard, A., Ogunsola, J., Perona-Wright, G., Ngoyi, D. M., Kuispond, N., Bucheton, B., Camara, M., Kajimura, S., Bénézech, C., Mabbott, N. A., MacLeod, A., Quintana, J. F. (2023) IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection. Nature Communications, 14, (doi: 10.1038/s41467-023-42918-8)

Nguyen, T.-H., Silva-Alvim, F. A. L., Hills, A., Blatt, M. R. (2023) OnGuard3e: a predictive, ecophysiology‐ready tool for gas exchange and photosynthesis research. Plant, Cell and Environment, 46, pp. 3644-3658. (doi: 10.1111/pce.14674)

Sannino, D. R., Dobson, A. J. (2023) Acetobacter pomorum in the Drosophila gut microbiota buffers against host metabolic impacts of dietary preservative formula and batch variation in dietary yeast. Applied and Environmental Microbiology, 89, (doi: 10.1128/aem.00165-23)

James, A. B., Sharples, C., Laird, J., Armstrong, E. M., Guo, W., Tzioutziou, N., Zhang, R., Brown, J. W.S., Nimmo, H., Jones, M. (2023) REVEILLE2 thermosensitive splicing: a molecular basis for the integration of nocturnal temperature information by the Arabidopsis circadian clock. New Phytologist, (doi: 10.1111/nph.19339)

Ward, J., Lyall, L. M., Cullen, B., Strawbridge, R. J., Zhu, X., Stanciu, I., Aman, A., Niedzwiedz, C. L., Anderson, J., Bailey, M. E.S., Lyall, D. M., Pell, J. P. (2023) Consistent effects of the genetics of happiness across the lifespan and ancestries in multiple cohorts. Scientific Reports, 13, (doi: 10.1038/s41598-023-43193-9)

Quint, M. et al. (2023) 25 years of thermomorphogenesis research: milestones and perspectives. Trends in Plant Science, 28, pp. 1089-1100. (doi: 10.1016/j.tplants.2023.07.001)

Dornan, A. J., Halberg, K. V., Beuter, L.-K., Davies, S. A., Dow, J. A.T. (2023) Compromised junctional integrity phenocopies age-dependent renal dysfunction in Drosophila Snakeskin mutants. Journal of Cell Science, 136, (doi: 10.1242/jcs.261118)

Madsen, M. A., Semerdzhiev, S., Twigg, J. D., Moss, C., Bavington, C. D., Amtmann, A. (2023) Environmental modulation of exopolysaccharide production in the cyanobacterium Synechocystis 6803. Applied Microbiology and Biotechnology, 107, pp. 6121-6134. (doi: 10.1007/s00253-023-12697-9)

Harris, C. J., Amtmann, A., Ton, J. (2023) Epigenetic processes in plant stress priming: open questions and new approaches. Current Opinion in Plant Biology, 75, (doi: 10.1016/j.pbi.2023.102432)

Prasetyaningrum, P., Litthauer, S., Vegliani, F., Battle, M. W., Wood, M. W., Liu, X., Dickson, C., Jones, M. A. (2023) Inhibition of RNA degradation integrates the metabolic signals induced by osmotic stress into the Arabidopsis circadian system. Journal of Experimental Botany, 74, pp. 5805-5819. (doi: 10.1093/jxb/erad274)

Dobson, A., Voigt, S., Kumpitsch, L., Langer, L., Voigt, E., Ibrahim, R., Dowling, D., Reinhardt, K. (2023) Mitonuclear interactions shape both direct and parental effects of diet on fitness, and involve a SNP in mitoribosomal 16s rRNA. PLoS Biology, 21, (doi: 10.1371/journal.pbio.3002218)

Perrella, G., Fasano, C., Donald, N. A., Daddiego, L., Fang, W., Martignago, D., Carr, C., Conti, L., Herzyk, P., Amtmann, A. (2023) Histone Deacetylase Complex 1 and Histone 1 epigenetically moderate stress responsiveness of Arabidopsis thaliana seedlings. New Phytologist, (doi: 10.1111/nph.19165)

Antoniou-Kourounioti, R. L., Meschichi, A., Reeck, S., Berry, S., Menon, G., Zhao, Y., Fozard, J., Holmes, T., Zhao, L., Wang, H., Hartley, M., Dean, C., Rosa, S., Howard, M. (2023) Integrating analog and digital modes of gene expression at Arabidopsis FLC. eLife, 12, (doi: 10.7554/elife.79743)

Nguyen, T. B.-A., Lefoulon, C., Nguyen, T.-H., Blatt, M. R., Carroll, W. (2023) Engineering stomata for enhanced carbon capture and water-use efficiency. Trends in Plant Science, (doi: 10.1016/j.tplants.2023.06.002)

Karnik, R., Blatt, M. R. (2023) Analyzing protein–protein interactions using the split-ubiquitin system. Humana Press

Auge, G., Hankofer, V., Groth, M., Antoniou-Kourounioti, R., Ratikainen, I., Lampei, C. (2023) Plant environmental memory: implications, mechanisms, and opportunities for plant scientists and beyond. AoB Plants, 15, (doi: 10.1093/aobpla/plad032)

Trovato, M., Brini, F., Mseddi, K., Rhizopoulou, S., Jones, M. A. (2023) A holistic and sustainable approach linked to drought tolerance of Mediterranean crops. Frontiers in Plant Science, 14, (doi: 10.3389/fpls.2023.1167376)

Durrani, Z., Kinnaird, J., Cheng, C. W., Brühlmann, F., Capewell, P., Jackson, A., Larcombe, S., Olias, P., Weir, W., Shiels, B. (2023) A parasite DNA binding protein with potential to influence disease susceptibility acts as an analogue of mammalian HMGA transcription factors. PLoS ONE, 18, (doi: 10.1371/journal.pone.0286526)

Cullen, B., Gameroff, M. J., Ward, J., Bailey, M. E.S., Lyall, D. M., Lyall, L. M., MacSweeney, N., Murphy, E., Sangha, N., Shen, X., Strawbridge, R. J., van Dijk, M. T., Zhu, X., Smith, D. J., Talati, A., Whalley, H. C., Cavanagh, J., Weissman, M. M. (2023) Cognitive function in people with familial risk of depression. JAMA Psychiatry, 80, pp. 610-620. (doi: 10.1001/jamapsychiatry.2023.0716)

Sabando, A. R., Lafuente, E. U., Galbete, A., Ciosi, M., Amigot, F. G., Solaesa, V. G., Martínez, V. Á., Martinez-Descals, A., Mila, M., Trujillo-Tiebas, M. J., López-Sendón, J. L., Fenollar-Cortés, M., Legarda, I., Noguera, S. B., Millán, J. M., Durán-Herrera, C., Monckton, D. G., Ramos-Arroyo, M. A. (2023) Spanish HTT gene study reveals haplotype and allelic diversity with possible implications for germline expansion dynamics in Huntington disease. Human Molecular Genetics, 32, pp. 897-906. (doi: 10.1093/hmg/ddac224)

Arora, S. et al. (2023) A wheat kinase and immune receptor form host-specificity barriers against the blast fungus. Nature Plants, 9, pp. 385-392. (doi: 10.1038/s41477-023-01357-5)

Abioye, J., Lawson‐Williams, M., Lecanda, A., Calhoon, B., McQue, A. L., Colloms, S. D., Stark, W. M., Olorunniji, F. J. (2023) High fidelity one‐pot DNA assembly using orthogonal serine integrases. Biotechnology Journal, 18, (doi: 10.1002/biot.202200411)

Rezig, I. M., Yaduma, W. G., Gould, G. W., McInerny, C. J. (2023) The role of anillin/Mid1p during medial division and cytokinesis: from fission yeast to cancer cells. Cell Cycle, 22, pp. 633-644. (doi: 10.1080/15384101.2022.2147655)

Montaño, S. P., Rowland, S.-J., Fuller, J. R., Burke, M. E., MacDonald, A. I., Boocock, M. R., Stark, W. M., Rice, P. A. (2023) Structural basis for topological regulation of Tn3 resolvase. Nucleic Acids Research, 51, pp. 1001-1018. (doi: 10.1093/nar/gkac733)

Morales, F., Corrales, E., Vásquez, M., Zhang, B., Fernández, H., Alvarado, F., Cortés, S., Santamaría-Ulloa, C., Cooper, A., McIlwaine, E., Cumming, S. A., Adam, B., Krahe, R., Puymirat, J., Schoser, B., Timchenko, L., Ashizawa, T., Thornton, C., Monckton, D. G., Krahe, R., Monckton, D. G. (2023) Individual-specific levels of CTG•CAG somatic instability are shared across multiple tissues in myotonic dystrophy type 1. Human Molecular Genetics, 32, pp. 621-631. (doi: 10.1093/hmg/ddac231)

Gallusci, P., Agius, D. R., Moschou, P. N., Dobránszki, J., Kaiserli, E., Martinelli, F. (2023) Deep inside the epigenetic memories of stressed plants. Trends in Plant Science, 28, pp. 142-153. (doi: 10.1016/j.tplants.2022.09.004)

Benoit, J. B., McCluney, K. E., DeGennaro, M. J., Dow, J. A.T. (2023) Dehydration dynamics in terrestrial arthropods: from water sensing to trophic interactions. Annual Review of Entomology, 68, pp. 129-149. (doi: 10.1146/annurev-ento-120120-091609)

Queiroz, M. V., Battle, M. W., Jones, M. A. (2023) Interactions between photosynthesis and the circadian system. Burleigh Dodds Science Publishing

McInnes, K. J., van der Hooft, J. J.J., Sharma, A., Herzyk, P., Hundleby, P. A.C., Schoonbeek, H.-J., Amtmann, A., Ridout, C., Jenkins, G. I. (2023) Overexpression of Brassica napus COMT1 in Arabidopsis heightens UV-B-mediated resistance to Plutella xylostella herbivory. Photochemical and Photobiological Sciences, 22, pp. 2341-2356. (doi: 10.1007/s43630-023-00455-9)

2022

Seale, M., Zhdanov, O., Soons, M. B., Cummins, C., Kroll, E., Blatt, M. R., Zare-Behtash, H., Busse, A., Mastropaolo, E., Bullock, J. M., Viola, I. M., Nakayama, N. (2022) Environmental morphing enables informed dispersal of the dandelion diaspore. eLife, 11, (doi: 10.7554/eLife.81962)

Krumrie, S., Capewell, P., McDonald, M., Dunbar, D., Panarese, R., Katzer, F., El Sakka, N., Mellor, D., Alexander, C. L., Weir, W. (2022) Molecular characterisation of Giardia duodenalis from human and companion animal sources in the United Kingdom using an improved triosephosphate isomerase molecular marker. Current Research in Parasitology and Vector-Borne Diseases, 2, (doi: 10.1016/j.crpvbd.2022.100105)

Oliwa, A., Hocking, C., Hamilton, M. J., Mclean, J., Cumming, S., Ballantyne, B., Jampana, R., Longman, C., Monckton, D. G., Farrugia, M. E. (2022) Masseter muscle volume as a disease marker in adult-onset myotonic dystrophy type 1. Neuromuscular Disorders, 32, pp. 893-902. (doi: 10.1016/j.nmd.2022.09.005)

Lieberman-Lazarovich, M., Kaiserli, E., Bucher, E., Mladenov, V. (2022) Natural and induced epigenetic variation for crop improvement. Current Opinion in Plant Biology, 70, (doi: 10.1016/j.pbi.2022.102297)

Taylor, A. S., Barros, D., Gobet, N., Schuepbach, T., McAllister, B., Aeschbach, L., Randall, E. L., Trofimenko, E., Heuchan, E. R., Barszcz, P., Ciosi, M., Morgan, J., Hafford-Tear, N. J., Davidson, A. E., Massey, T. H., Monckton, D. G., Jones, L., network, R. I. o. t. E. H.’s. d., Xenarios, I., Dion, V. (2022) Repeat Detector: versatile sizing of expanded tandem repeats and identification of interrupted alleles from targeted DNA sequencing. NAR Genomics and Bioinformatics, 4, (doi: 10.1093/nargab/lqac089)

Martínez Corrales, G., Li, M., Svermova, T., Goncalves, A., Voicu, D., Dobson, A. J., Southall, T. D., Alic, N. (2022) Transcriptional memory of dFOXO activation in youth curtails later-life mortality through chromatin remodelling and Xbp1. Nature Aging, 2, pp. 1176-1190. (doi: 10.1038/s43587-022-00312-x)

Teige, M., Jones, M., Toledo-Ortiz, G. (2022) Plant organellar signalling—back and forth and intertwined with cellular signalling. Journal of Experimental Botany, 73, pp. 7103-7104. (doi: 10.1093/jxb/erac383)

Horaruang, W., Klejchová, M., Carroll, W., Silva-Alvim, F. A.L., Waghmare, S., Papanatsiou, M., Amtmann, A., Hills, A., Alvim, J. C., Blatt, M. R., Zhang, B. (2022) Engineering a K+ channel 'sensory antenna' enhances stomatal kinetics, water use efficiency and photosynthesis. Nature Plants, 8, pp. 1262-1274. (doi: 10.1038/s41477-022-01255-2)

Eshel, G., Duppen, N., Wang, G., Oh, D.‐H., Kazachkova, Y., Herzyk, P., Amtmann, A., Gordon, M., Chalifa‐Caspi, V., Oscar, M. A., Bar‐David, S., Marshall‐Colon, A., Dassanayake, M., Barak, S. (2022) Positive selection and heat‐response transcriptomes reveal adaptive features of the Brassicaceae desert model, Anastatica hierochuntica. New Phytologist, 236, pp. 1006-1026. (doi: 10.1111/nph.18411)

Fang, W., Vellutini, E., Perrella, G., Kaiserli, E. (2022) TANDEM ZINC-FINGER/PLUS3 regulates phytochrome B abundance and signaling to fine-tune hypocotyl growth. Plant Cell, 34, pp. 4213-4231. (doi: 10.1093/plcell/koac236)

Dawson, J., Baine-Savanhu, F. K., Ciosi, M., Maxwell, A., Monckton, D. G., Krause, A. (2022) A probable cis-acting genetic modifier of Huntington disease frequent in individuals with African ancestry. Human Genetics and Genomics Advances, 3, (doi: 10.1016/j.xhgg.2022.100130)

Bain, S. A., Meagher, T. R., Barker, D. (2022) Design, delivery and evaluation of a bioinformatics education workshop for 13-16-year-olds. Journal of Biological Education, 56, pp. 570-580. (doi: 10.1080/00219266.2020.1858932)

Patitaki, E., Schivre, G., Zioutopoulou, A., Perrella, G., Bourbousse, C., Barneche, F., Kaiserli, E. (2022) Light, chromatin, action: nuclear events regulating light signaling in Arabidopsis. New Phytologist, 236, pp. 333-349. (doi: 10.1111/nph.18424)

Ciosi, M., Young, R., Kwak, S., Monckton, D. G. (2022) Longitudinal Analysis of Somatic Expansion of the HTT Repeat in Blood as a Potential Biomarker of Somatic Instability in Huntingon Disease. (doi: 10.1136/jnnp-2022-ehdn.57)

Ruiz de Sabando, A., Ciosi, M., Galbete, A., Monckton, D. G., Ramos-Arroyo, M. A. (2022) Somatic Mosaicism of the HTT Cag Repeat in Intermediate Allele Carriers with Neurocognitive Symptoms Compatible with Huntington Disease. (doi: 10.1136/jnnp-2022-ehdn.1)

Liao, X., Jenkins, G. I. (2022) Cysteines have a role in conformation of the UVR8 photoreceptor. Plant Journal, 111, pp. 583-594. (doi: 10.1111/tpj.15841)

Dow, J. A.T., Simons, M., Romero, M. F. (2022) Drosophila melanogaster: a simple genetic model of kidney structure, function and disease. Nature Reviews Nephrology, 18, pp. 417-434. (doi: 10.1038/s41581-022-00561-4)

Xu, J., Liu, Y., Lib, H., Tarashansky, A. J., Kalicki, C. H., Hung, R.-J., Hua, Y., Comjean, A., Kolluru, S. S., Wang, B., Quake, S. R., Luo, L., McMahon, A. P., Dow, J. A.T., Perrimon, N. (2022) Transcriptional and functional motifs defining renal function revealed by single-nucleus RNA sequencing. Proceedings of the National Academy of Sciences of the United States of America, 119, (doi: 10.1073/pnas.2203179119)

McInerny, C. J., Crochet, P.‐A., Dudley, S. P., on behalf of BOURC & AERC, (2022) Assessing vagrants from translocated populations and defining self-sustaining populations of non-native, naturalized and translocated avian species. Ibis, 164, pp. 924-928. (doi: 10.1111/ibi.13067)

McInerny, C. J., Musgrove, A. J., Gilroy, J. J., Dudley, S. P., the British Ornithologists’ Union Records Committee (BOURC), (2022) The British list: a checklist of birds of Britain (10th edition) Ibis, 164, pp. 860-910. (doi: 10.1111/ibi.13065)

de Carbonnel, M., Stormonth-Darling, J. M., Liu, W., Kuziak, D., Jones, M. A. (2022) Realising the environmental potential of vertical farming systems through advances in plant photobiology. Biology, 11, (doi: 10.3390/biology11060922)

Lee, J.-M. et al. (2022) Genetic modifiers of Huntington disease differentially influence motor and cognitive domains. American Journal of Human Genetics, 109, pp. 885-899. (doi: 10.1016/j.ajhg.2022.03.004)

Hamilton, M. J., Atalaia, A., McLean, J., Cumming, S., Evans, J. J., Ballantyne, B., Jampana, R., The Scottish Myotonic Dystrophy Consortium, , Longman, C., Livingston, E., van der Plas, E., Koscik, T., Nopoulos, P., Farrugia, M. E., Monckton, D. G. (2022) Clinical and neuroradiological correlates of sleep in myotonic dystrophy type 1. Neuromuscular Disorders, 32, pp. 377-389. (doi: 10.1016/j.nmd.2022.02.003)

Thu, N. B.A., Amtmann, A., Blatt, M. R., Nguyen, T.-H. (2022) Stomata under salt stress—what can mechanistic modeling tell us? Academic Press

McAllister, B. et al. (2022) Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset. Nature Neuroscience, 25, pp. 446-457. (doi: 10.1038/s41593-022-01033-5)

Antonijevic, I. A., Bettencourt, B. R., Bialek, P., Ge, P., Ding, S.-Y., Lai, G., Hedde, J., Asp, E., Seth, M., Marnellos, G., Whartenby, K. A., Monckton, D. G., Tabrizi, S. J. (2022) Suppression of somatic expansion as a novel therapeutic approach for Huntington disease and other repeat expansion disorders. GEN Biotechnology, 1, pp. 163-175. (doi: 10.1089/genbio.2021.0012)

Zioutopoulou, A., Patitaki, E., O'Donnell, L., Kaiserli, E. (2022) Low fluence ultraviolet-B promotes ultraviolet resistance 8-modulated flowering in Arabidopsis. Frontiers in Plant Science, 13, (doi: 10.3389/fpls.2022.840720)

Krumrie, S., Capewell, P., Smith-Palmer, A., Mellor, D., Weir, W., Alexander, C. L. (2022) A scoping review of risk factors and transmission routes associated with human giardiasis outbreaks in high-income settings. Current Research in Parasitology and Vector-Borne Diseases, 2, (doi: 10.1016/j.crpvbd.2022.100084)

Li, H. et al. (2022) Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. Science, 375, (doi: 10.1126/science.abk2432)

Guarino, F., Cicatelli, A., Castiglione, S., Agius, D. R., Orhun, G. E., Fragkostefanakis, S., Leclercq, J., Dobránszki, J., Kaiserli, E., Lieberman-Lazarovich, M., Sõmera, M., Sarmiento, C., Vettori, C., Paffetti, D., Poma, A. M. G., Moschou, P. N., Gašparović, M., Yousefi, S., Vergata, C., Berger, M. M. J., Gallusci, P., Miladinović, D., Martinelli, F. (2022) An epigenetic alphabet of crop adaptation to climate change. Frontiers in Genetics, 13, (doi: 10.3389/fgene.2022.818727)

Blatt, M. R., Jezek, M., Lew, V. L., Hills, A. (2022) What can mechanistic models tell us about guard cells, photosynthesis, and water use efficiency? Trends in Plant Science, 27, pp. 166-179. (doi: 10.1016/j.tplants.2021.08.010)

Larcombe, S. D., Capewell, P., Jensen, K., Weir, W., Kinnaird, J., Glass, E. J., Shiels, B. R. (2022) Susceptibility to disease (tropical theileriosis) is associated with differential expression of host genes that possess motifs recognised by a pathogen DNA binding protein. PLoS ONE, 17, (doi: 10.1371/journal.pone.0262051)

van der Plas, E., Long, J. D., Koscik, T. R., Magnotta, V., Monckton, D. G., Cumming, S. A., Gottschalk, A. C., Hefti, M., Gutmann, L., Nopoulos, P. C. (2022) Blood-based markers of neuronal injury in adult-onset myotonic dystrophy type 1. Frontiers in Neurology, 12, (doi: 10.3389/fneur.2021.791065)

Bain, S. A., Plaisier, H., Anderson, F., Cook, N., Crouch, K., Meagher, T. R., Ritchie, M. G., Wallace, E. W. J., Barker, D. (2022) Bringing bioinformatics to schools with the 4273pi project. PLoS Computational Biology, 18, (doi: 10.1371/journal.pcbi.1009705)

Morales, F., Corrales, E., Zhang, B., Vásquez, M., Santamaría-Ulloa, C., Quesada, H., Sirito, M., Estecio, M. R., Monckton, D. G., Krahe, R. (2022) Myotonic dystrophy type 1 (DM1) clinical sub-types and CTCF site methylation status flanking the CTG expansion are mutant allele length-dependent. Human Molecular Genetics, 31, pp. 262-274. (doi: 10.1093/hmg/ddab243)

Krause, S. A., Overend, G., Dow, J. A.T., Leader, D. P. (2022) FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas. Nucleic Acids Research, 50, pp. D1010-D1015. (doi: 10.1093/nar/gkab971)

Tank, R., Ward, J., Flegal, K. E., Smith, D. J., Bailey, M. E.S., Cavanagh, J., Lyall, D. M. (2022) Association between polygenic risk for Alzheimer’s disease, brain structure and cognitive abilities in UK Biobank. Neuropsychopharmacology, 47, pp. 564-569. (doi: 10.1038/s41386-021-01190-4)

Gilroy, J., McInerny, C., Dudley, S., Balmer, D., Batty, C., Crochet, P.-A., French, P., Golley, M., Lees, A., Stoddart, A. (2022) British Ornithologists' Union Records Committee (BOURC): 53rd Report (January 2022) Ibis, 164, pp. 363-368. (doi: 10.1111/ibi.13014)

Gilroy, J., McInerny, C., Dudley, S., Batty, C., Crochet, P.-A., French, P., Golley, M., Lees, A., Stoddart, A. (2022) British Ornithologists’ Union Records Committee (BOURC): 54th Report (July 2022) Ibis, 164, pp. 929-931. (doi: 10.1111/ibi.13064)

Lyall, D. M., Quinn, T., Lyall, L. M., Ward, J., Anderson, J. J., Smith, D. J., Stewart, W., Strawbridge, R. J., Bailey, M. E.S., Cullen, B. (2022) Quantifying bias in psychological and physical health in the UK Biobank imaging sub-sample. Brain Communications, 4, (doi: 10.1093/braincomms/fcac119)

Zhdanov, O., Blatt, M. R., Zare-Behtash, H., Busse, A. (2022) Unidirectional versus bidirectional brushing: simulating wind influence on Arabidopsis thaliana. Quantitative Plant Biology, 3, (doi: 10.1017/qpb.2021.14)

2021

Blatt, M. (2021) Ae fond fareweel. Plant Physiology, 187, pp. 2341-2343. (doi: 10.1093/plphys/kiab467)

Zioutopoulou, A., Patitaki, E., Xu, T., Kaiserli, E. (2021) The epigenetic mechanisms underlying thermomorphogenesis and heat stress responses in Arabidopsis. Plants, 10, (doi: 10.3390/plants10112439)

Rendón-Anaya, M., Wilson, J., Sveinsson, S., Fedorkov, A., Cottrell, J., Bailey, M. E.S., Ruņģis, D., Lexer, C., Jansson, S., Robinson, K. M., Street, N. R., Ingvarsson, P. K. (2021) Adaptive introgression facilitates adaptation to high latitudes in European aspen (Populus tremula L.) Molecular Biology and Evolution, 38, pp. 5034-5050. (doi: 10.1093/molbev/msab229)

Girard, A., Cooper, A., Mabbott, S., Bradley, B., Asiala, S., Jamieson, L., Clucas, C., Capewell, P., Marchesi, F., Gibbins, M. P., Hentzschel, F., Marti, M., Quintana, J. F., Garside, P., Faulds, K., MacLeod, A., Graham, D. (2021) Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis. PLoS Pathogens, 17, (doi: 10.1371/journal.ppat.1010060)

Bain, S. A., Marshall, H., de la Filia, A. G., Laetsch, D. R., Husnik, F., Ross, L. (2021) Sex‐specific expression and DNA methylation in a species with extreme sexual dimorphism and paternal genome elimination. Molecular Ecology, 30, pp. 5687-5703. (doi: 10.1111/mec.15842)

Jani, B. D., Nicholl, B. I., Hanlon, P., Mair, F. S., Gill, J. M.R., Gray, S. R., Celis-Morales, C. A., Ho, F. K., Lyall, D. M., Anderson, J. J., Hastie, C. E., Bailey, M. E.S., Foster, H., Pell, J. P., Welsh, P., Sattar, N. (2021) Family history of diabetes and risk of SARS-COV-2 in UK Biobank: a prospective cohort study. Endocrinology, Diabetes and Metabolism, 4, (doi: 10.1002/edm2.283)

Dow, J. A.T., Krause, S. A., Herzyk, P. (2021) Updates on ion and water transport by the Malpighian tubule. Current Opinion in Insect Science, 47, pp. 31-37. (doi: 10.1016/j.cois.2021.02.018)

Bonfini, A., Dobson, A. J., Duneau, D., Revah, J., Liu, X., Houtz, P., Buchon, N. (2021) Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size. eLife, 10, (doi: 10.7554/elife.64125)

Jezek, M., Silva-Alvim, F. A.L., Hills, A., Donald, N., Ishka, M. R., Shadbolt, J., He, B., Lawson, T., Harper, J. F., Wang, Y., Lew, V. L., Blatt, M. R. (2021) Guard cell endomembrane Ca2+-ATPases underpin a ‘carbon memory’ of photosynthetic assimilation that impacts on water-use efficiency. Nature Plants, 7, pp. 1301-1313. (doi: 10.1038/s41477-021-00966-2)

Koyama, T., Terhzaz, S., Naseem, M. T., Nagy, S., Rewitz, K., Dow, J. A.T., Davies, S. A., Halberg, K. V. (2021) A nutrient-responsive hormonal circuit mediates an inter-tissue program regulating metabolic homeostasis in adult Drosophila. Nature Communications, 12, (doi: 10.1038/s41467-021-25445-2)

Channumsin, M., Ciosi, M., Masiga, D., Auty, H., Turner, C. M., Kilbride, E., Mable, B. K. (2021) Blood meal analysis of tsetse flies (Glossina pallidipes: Glossinidae) reveals higher host fidelity on wild compared with domestic hosts. Wellcome Open Research, 6, (doi: 10.12688/wellcomeopenres.16978.1)

Kakoulidou, I., Avramidou, E. V., Baránek, M., Brunel-Muguet, S., Farrona, S., Johannes, F., Kaiserli, E., Lieberman-Lazarovich, M., Martinelli, F., Mladenov, V., Testillano, P. S., Vassileva, V., Maury, S. (2021) Epigenetics for crop improvement in times of global change. Biology, 10, (doi: 10.3390/biology10080766)

Miller, J. N., Kruger, A., Moser, D. J., Gutmann, L., van der Plas, E., Koscik, T. R., Cumming, S. A., Monckton, D. G., Nopoulos, P. C. (2021) Cognitive deficits, apathy, and hypersomnolence represent the core brain symptoms of adult-onset myotonic dystrophy type 1. Frontiers in Neurology, 12, (doi: 10.3389/fneur.2021.700796)

Mladenov, V., Fotopoulos, V., Kaiserli, E., Karalija, E., Maury, S., Baranek, M., Segal, N., Testillano, P. S., Vassileva, V., Pinto, G., Nagel, M., Hoenicka, H., Miladinović, D., Gallusci, P., Vergata, C., Kapazoglou, A., Abraham, E., Tani, E., Gerakari, M., Sarri, E., Avramidou, E., Gašparović, M., Martinelli, F. (2021) Deciphering the epigenetic alphabet involved in transgenerational stress memory in crops. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22137118)

Diamantopoulou, C., Christoforou, E., Dominoni, D. M., Kaiserli, E., Czyzewski, J., Mirzai, N., Spatharis, S. (2021) Wavelength-dependent effects of artificial light at night on phytoplankton growth and community structure. Proceedings of the Royal Society of London Series B: Biological Sciences, 288, (doi: 10.1098/rspb.2021.0525)

Zhao, Y., Zhu, P., Hepworth, J., Bloomer, R., Antoniou-Kourounioti, R. L., Doughty, J., Heckmann, A., Xu, C., Yang, H., Dean, C. (2021) Natural temperature fluctuations promote COOLAIR regulation of FLC. Genes and Development, 35, pp. 888-898. (doi: 10.1101/gad.348362.121)

Eaglesfield, R., Madsen, M. A., Sanyal, S., Reboud, J., Amtmann, A. (2021) Co-translational recruitment of ribosomes in minimal protocells recreates a translocon-independent mechanism of proteorhodopsin biogenesis. iScience, 24, (doi: 10.1016/j.isci.2021.102429)

Stevens, J., Jones, M. A., Lawson, T. (2021) Diverse physiological and physical responses among wild, landrace and elite barley varieties point to novel breeding opportunities. Agronomy, 11, (doi: 10.3390/agronomy11050921)

Johnston, K. J.A., Ward, J., Ray, P. R., Adams, M. J., McIntosh, A. M., Smith, B. H., Strawbridge, R. J., Price, T. J., Smith, D. J., Nicholl, B. I., Bailey, M. E.S. (2021) Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 17, (doi: 10.1371/journal.pgen.1009428)

Wenninger, S., Cumming, S. A., Gutschmidt, K., Okkersen, K., Jimenez-Moreno, A. C., Daidj, F., Lochmüller, H., Hogarth, F., Knoop, H., Bassez, G., Monckton, D. G., van Engelen, B. G.M., Schoser, B. (2021) Associations between variant repeat interruptions and clinical outcomes in myotonic dystrophy type 1. Neurology Genetics, 7, (doi: 10.1212/NXG.0000000000000572)

Klejchova, M., Silva-Alvim, F. A.L., Blatt, M. R., Alvim, J. C. (2021) Membrane voltage as a dynamic platform for spatio-temporal signalling, physiological and developmental regulation. Plant Physiology, 185, pp. 1523-1541. (doi: 10.1093/plphys/kiab032)

van der Plas, E., Koscik, T. R., Magnotta, V., Cumming, S. A., Monckton, D., Gutmann, L., Nopoulos, P. (2021) Neurocognitive features of motor premanifest individuals with myotonic dystrophy type 1. Neurology Genetics, 7, (doi: 10.1212/NXG.0000000000000577)

Gray, A., Capewell, P., Zadoks, R., Taggart, M. A., French, A. S., Katzer, F., Shiels, B. R., Weir, W. (2021) Wild deer in the United Kingdom are a potential reservoir for the livestock parasite. Current Research in Parasitology and Vector-Borne Diseases, 1, (doi: 10.1016/j.crpvbd.2021.100019)

Koscik, T. R., van der Plas, E., Gutmann, L., Cumming, S. A., Monckton, D. G., Magnotta, V., Shields, R. K., Nopoulos, P. C. (2021) White matter microstructure relates to motor outcomes in myotonic dystrophy type 1 independently of disease duration and genetic burden. Scientific Reports, 11, (doi: 10.1038/s41598-021-84520-2)

Cumming, S. A., Oliwa, A., Stevens, G., Ballantyne, B., Mann, C., Razvi, S., Longman, C., Monckton, D. G., Farrugia, M. E. (2021) A DM1 patient with CCG variant repeats: reaching the diagnosis. Neuromuscular Disorders, 31, pp. 232-238. (doi: 10.1016/j.nmd.2020.12.005)

Perrella, G., Zioutopoulou, A., Hamilton, A., Kaiserli, E. (2021) Photobody detection using immunofluorescence and super-resolution imaging in Arabidopsis. Humana

Zhdanov, O., Blatt, M. R., Zare-Behtash, H., Busse, A. (2021) Wind-evoked anemotropism affects the morphology and mechanical properties of Arabidopsis. Journal of Experimental Botany, 72, pp. 1906-1918. (doi: 10.1093/jxb/eraa541)

Ciosi, M., Cumming, S. A., Chatzi, A., Larson, E., Tottey, W., Lomeikaite, V., Hamilton, G., Wheeler, V. C., Pinto, R. M., Kwak, S., Morton, A. J., Monckton, D. G. (2021) Approaches to sequence the HTT CAG repeat expansion and quantify repeat length variation. Journal of Huntington's Disease, 10, pp. 53-74. (doi: 10.3233/jhd-200433)

Gomes-Pereira, M., Monckton, D. G. (2021) Chronic exposure to cadmium and antioxidants does not affect the dynamics of expanded CAG•CTG trinucleotide repeats in a mouse cell culture system of unstable DNA. Frontiers in Cellular Neuroscience, 14, (doi: 10.3389/fncel.2020.606331)

Capewell, P., Krumrie, S., Katzer, F., Alexander, C. L., Weir, W. (2021) Molecular epidemiology of Giardia infections in the genomic era. Trends in Parasitology, 37, pp. 142-153. (doi: 10.1016/j.pt.2020.09.013)

Antoniou-Kourounioti, R. L., Zhao, Y., Dean, C., Howard, M. (2021) Feeling every bit of winter - distributed temperature sensitivity in vernalization. Frontiers in Plant Science, 12, (doi: 10.3389/fpls.2021.628726)

Madsen, M. A., Hamilton, G., Herzyk, P., Amtmann, A. (2021) Environmental regulation of PndbA600, an auto-inducible promoter for two-stage industrial biotechnology in cyanobacteria. Frontiers in Bioengineering and Biotechnology, 8, (doi: 10.3389/fbioe.2020.619055)

Strawbridge, R. J. et al. (2021) The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals. Scientific Reports, 11, (doi: 10.1038/s41598-020-79964-x)

Gilroy, J., McInerny, C., Dudley, S., Balmer, D., Batty, C., Crochet, P.-A., French, P., Lees, A., Musgrove, A., Stoddart, A. (2021) British Ornithologists’ Union Records Committee (BOURC): 52nd Report (January 2021) Ibis, 163, pp. 305-308. (doi: 10.1111/ibi.12900)

Rezig, I. M., Yaduma, W. G., Gould, G. W., McInerny, C. J. (2021) Anillin/Mid1p interacts with the ESCRT-associated protein Vps4p and mitotic kinases to regulate cytokinesis in fission yeast. Cell Cycle, 20, pp. 1845-1860. (doi: 10.1080/15384101.2021.1962637)

2020

Parry, G., Benitez-Alfonso, Y., Gibbs, D. J., Grant, M., Harper, A., Harrison, C. J., Kaiserli, E., Leonelli, S., May, S., McKim, S., Spoel, S., Turnbull, C., van der Hoorn, R. A.L., Murray, J. (2020) How to build an effective research network: lessons from two decades of the GARNet plant science community. Journal of Experimental Botany, 71, pp. 6881-6889. (doi: 10.1093/jxb/eraa397)

Dornan, A.J., Halberg, K.A., Beuter, L.-K., Davies, S.-A., Dow, J.A.T. (2020) The septate junction protein Snakeskin is critical for epithelial barrier function and tissue homeostasis in the Malpighian tubules of adult Drosophila. bioRxiv, (doi: 10.1101/2020.12.14.422678)

Zhdanov, O., Blatt, M. R., Cammarano, A., Zare-Behtash, H., Busse, A. (2020) A new perspective on mechanical characterisation of Arabidopsis stems through vibration tests. Journal of the Mechanical Behavior of Biomedical Materials, 112, (doi: 10.1016/j.jmbbm.2020.104041)

Breton, É., Légaré, C., Overend, G., Guay, S.-P., Monckton, D., Mathieu, J., Gagnon, C., Richer, L., Gallais, B., Bouchard, L. (2020) DNA methylation at the DMPK gene locus is associated with cognitive functions in myotonic dystrophy type 1. Epigenomics, 12, pp. 2051-2064. (doi: 10.2217/epi-2020-0328)

Butt, G. R., Qayyum, Z. A., Jones, M. A. (2020) Plant defence mechanisms are modulated by the circadian system. Biology, 9, (doi: 10.3390/biology9120454)

Rowland, S.-J., Boocock, M. R., Burke, M. E., Rice, P. A., Stark, W. M. (2020) The protein-protein interactions required for assembly of the Tn3 resolution synapse. Molecular Microbiology, 114, pp. 952-965. (doi: 10.1111/mmi.14579)

Morris, J., Leung, S. S. Y., Bailey, M. E.S., Cullen, B., Ferguson, A., Graham, N., Johnston, K. J.A., Lyall, D. M., Lyall, L. M., Ward, J., Smith, D. J., Strawbridge, R. J. (2020) Exploring the role of contactins across psychological, psychiatric and cardiometabolic traits within UK Biobank. Genes, 11, (doi: 10.3390/genes11111326)

Waraich, N. F., Jain, S., Colloms, S. D., Stark, W. M., Burton, N. P., Maxwell, A. (2020) A novel decatenation assay for DNA topoisomerases using a singly-linked catenated substrate. BioTechniques, 69, pp. 356-362. (doi: 10.2144/btn-2020-0059)

Inoue, S.‐I., Kaiserli, E., Zhao, X., Waksman, T., Takemiya, A., Okumura, M., Takahashi, H., Seki, M., Shinozaki, K., Endo, Y., Sawasaki, T., Kinoshita, T., Zhang, X., Christie, J. M., Shimazaki, K.‐I. (2020) CIPK23 regulates blue light-dependent stomatal opening in Arabidopsis thaliana. Plant Journal, 104, pp. 679-692. (doi: 10.1111/tpj.14955)

Landfeldt, E., Nikolenko, N., Jimenez‑Moreno, C., Cumming, S., Monckton, D., Faber, C. G., Merkies, I. S.J., Gorman8, G., Turner, C., Lochmüller, H. (2020) Change over time in ability to perform activities of daily living in myotonic dystrophy type 1. Journal of Neurology, 267, pp. 3235-3242. (doi: 10.1007/s00415-020-09970-6)

Mähler, N., Schiffthaler, B., Robinson, K. M., Terebieniec, B. K., Vučak, M., Mannapperuma, C., Bailey, M. E.S., Jansson, S., Hvidsten, T. R., Street, N. R. (2020) Leaf shape in Populus tremula is a complex, omnigenic trait. Ecology and Evolution, 10, pp. 11922-11940. (doi: 10.1002/ece3.6691)

Ballester-Lopez, A., Koehorst, E., Linares-Pardo, I., Núñez-Manchón, J., Almendrote, M., Lucente, G., Arbex, A., Puente, C. P., Lucia, A., Monckton, D. G., Cumming, S. A., Pintos-Morell, G., Coll-Cantí, J., Ramos-Fransi, A., Martínez-Piñeiro, A., Nogales-Gadea, G. (2020) Preliminary findings on CTG expansion determination in different tissues from patients with myotonic dystrophy type 1. Genes, 11, (doi: 10.3390/genes11111321)

Ward, J., Tunbridge, E. M., Sandor, C., Lyall, L. M., Ferguson, A., Strawbridge, R. J., Lyall, D. M., Cullen, B., Graham, N., Johnston, K. J.A., Webber, C., Escott-Price, V., O'Donovan, M., Pell, J. P., Bailey, M. E.S., Harrison, P. J., Smith, D. J. (2020) The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function. Molecular Psychiatry, 25, pp. 3091-3099. (doi: 10.1038/s41380-019-0439-8)

de Rooij, P. G.H., Perrella, G., Kaiserli, E., van Zanten, M. (2020) The diverse and unanticipated roles of Histone deacetylase 9 in coordinating plant development and environmental acclimation. Journal of Experimental Botany, 71, pp. 6211-6225. (doi: 10.1093/jxb/eraa335)

Battle, M. W., Vegliani, F., Jones, M. A. (2020) Shades of green: untying the knots of green photoperception. Journal of Experimental Botany, 71, pp. 5764-5770. (doi: 10.1093/jxb/eraa312)

Jarad, M., Antoniou-Kourounioti, R. L., Hepworth, J., Qüesta, J. I. (2020) Unique and contrasting effects of light and temperature cues on plant transcriptional programs. Transcription, 11, pp. 134-159. (doi: 10.1080/21541264.2020.1820299)

Miller, J. N., van der Plas, E., Hamilton, M., Koscik, T. R., Gutmann, L., Cumming, S. A., Monckton, D. G., Nopoulos, P. C. (2020) Variant repeats within the DMPK CTG expansion protect function in myotonic dystrophy type 1. Neurology Genetics, 6, (doi: 10.1212/NXG.0000000000000504)

Hepworth, J., Antoniou-Kourounioti, R. L., Berggren, K., Selga, C., Tudor, E. H., Yates, B., Cox, D., Rose Collier Harris, B., Irwin, J. A., Howard, M., Säll, T., Holm, S., Dean, C. (2020) Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis FLC haplotypes. eLife, 9, (doi: 10.7554/eLife.57671)

Lu, A. T., Narayan, P., Grant, M. J., Langfelder, P., Wang, N., Kwak, S., Wilkinson, H., Chen, R. Z., Chen, J., Bawden, C. S., Rudiger, S. R., Ciosi, M., Chatzi, A., Maxwell, A., Hore, T. A., Aaronson, J., Rosinski, J., Preiss, A., Vogt, T. A., Coppola, G., Monckton, D., Snell, R. G., Yang, X. W., Horvarth, S. (2020) DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nature Communications, 11, (doi: 10.1038/s41467-020-18255-5)

Lefoulon, C., Boxall, S. F., Hartwell, J., Blatt, M. R. (2020) Crassulacean acid metabolism guard cell anion channel activity follows transcript abundance and is suppressed by apoplastic malate. New Phytologist, 227, pp. 1847-1857. (doi: 10.1111/nph.16640)

Larson, E. R., Ortmannová, J., Donald, N. A., Alvim, J., Blatt, M. R., Žárský, V. (2020) Synergy among exocyst and SNARE interactions identifies a functional hierarchy in secretion during vegetative growth. Plant Cell, 32, pp. 2951-2963. (doi: 10.1105/tpc.20.00280)

Perrella, G., Zioutopoulou, A., Headland, L. R., Kaiserli, E. (2020) The impact of light and temperature on chromatin organisation and plant adaptation. Journal of Experimental Botany, 71, pp. 5247-5255. (doi: 10.1093/jxb/eraa154)

Jezek, M., Hills, A., Blatt, M. R., Lew, V. L. (2020) A constraint-relaxation-recovery mechanism for stomatal dynamics. Plant, Cell and Environment, 42, pp. 2399-2410. (doi: 10.1111/pce.13568)

Liao, X., Liu, W., Yang, H.-Q., Jenkins, G. I. (2020) A dynamic model of UVR8 photoreceptor signaling in UV-B acclimated Arabidopsis. New Phytologist, 227, pp. 857-866. (doi: 10.1111/nph.16581)

Zhao, Y., Antoniou-Kourounioti, R. L., Calder, G., Dean, C., Howard, M. (2020) Temperature-dependent growth contributes to long-term cold sensing. Nature, 583, pp. 825-829. (doi: 10.1038/s41586-020-2485-4)

Ballester-Lopez, A., Linares-Pardo, I., Koehorst, E., Núñez-Manchón, J., Pintos-Morell, G., Coll-Cantí, J., Almendrote, M., Lucente, G., Arbex, A., Magaña, J. J., Murillo-Melo, N. M., Lucia, A., Monckton, D., Cumming, S. A., Ramos-Fransi, A., Martínez-Piñeiro, A., Nogales-Gadea, G. (2020) The need for establishing a universal CTG sizing method in myotonic dystrophy type 1. Genes, 11, (doi: 10.3390/genes11070757)

Kim, K.-H., Hong, E. P., Shin, J. W., Chao, M. J., Loupe, J., Gillis, T., Mysore, J. S., Holmans, P., Jones, L., Orth, M., Monckton, D. G., Long, J. D., Kwak, S., Lee, R., Gusella, J. F., MacDonald, M. E., Lee, J.-M. (2020) Genetic and functional analyses point to FAN1 as the source of multiple Huntington disease modifier effects. American Journal of Human Genetics, 107, pp. 96-110. (doi: 10.1016/j.ajhg.2020.05.012)

Flütsch, S., Wang, Y., Takemiya, A., Vialet-Chabrand, S. R., Klejchova, M., Nigro, A., Hills, A., Lawson, T., Blatt, M. R., Santelia, D. (2020) Guard cell starch degradation yields glucose for rapid stomatal opening in Arabidopsis. Plant Cell, 32, pp. 2325-2344. (doi: 10.1105/tpc.18.00802)

Perrella, G., Vellutini, E., Zioutopoulou, A., Patitaki, E., Headland, L. R., Kaiserli, E. (2020) Let it bloom: crosstalk between light and flowering signalling in Arabidopsis. Physiologia Plantarum, 169, pp. 301-311. (doi: 10.1111/ppl.13073)

Bain, S. A., Barker, D., Attwood, T. K. (2020) Bioinformatics: food detective – a practical guide. F1000Research, 9, (doi: 10.7490/f1000research.1118007.1)

Alfituri, O. A., Quintana, J. F., MacLeod, A., Garside, P., Benson, R. A., Brewer, J. M., Mabbott, N. A., Morrison, L. J., Capewell, P. (2020) To the skin and beyond: the immune response to African trypanosomes as they enter and exit the vertebrate host. Frontiers in Immunology, 11, (doi: 10.3389/fimmu.2020.01250)

Klejchová, M., Hills, A., Blatt, M. R. (2020) Predicting the unexpected in stomatal gas exchange: not just an open-and-shut case. Biochemical Society Transactions, 48, pp. 881-889. (doi: 10.1042/BST20190632)

Lewis, S. H., Ross, L., Bain, S. A., Pahita, E., Smith, S. A., Cordaux, R., Miska, E. A., Lenhard, B., Jiggins, F. M., Sarkies, P. (2020) ­­­­­­Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods. PLoS Genetics, 16, (doi: 10.1371/journal.pgen.1008864)

Capewell, P., Rupp, A., Fuentes, M., McDonald, M., Weir, W. (2020) Fatal Clostridium sordellii-mediated hemorrhagic and necrotizing gastroenteropathy in a dog: case report. BMC Veterinary Research, 16, (doi: 10.1186/s12917-020-02362-y)

Ellis, N. et al. (2020) Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s Disease. Biological Psychiatry, 87, pp. 857-865. (doi: 10.1016/j.biopsych.2019.12.010)

Woodling, N. S., Aleyakpo, B., Dyson, M. C., Minkley, L. J., Rajasingam, A., Dobson, A. J., Leung, K. H. C., Pomposova, S., Fuentealba, M., Alic, N., Partridge, L. (2020) The neuronal receptor tyrosine kinase Alk is a target for longevity. Aging Cell, 19, (doi: 10.1111/acel.13137)

Kurkiewicz, A., Cooper, A., McIlwaine, E., Cumming, S. A., Adam, B., Krahe, R., Puymirat, J., Schoser, B., Timchenko, L., Ashizawa, T., Thornton, C. A., Rogers, S., McClure, J. D., Monckton, D. G. (2020) Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial. PLoS ONE, 15, (doi: 10.1371/journal.pone.0231000)

Landfeldt, E., Nikolenko, N., Jimenez‐Moreno, C., Cumming, S., Monckton, D. G., Faber, C. G., Merkies, I. S.J., Gorman, G., Turner, C., Lochmüller, H. (2020) Activities of daily living in myotonic dystrophy type 1. Acta Neurologica Scandinavica, 141, pp. 380-387. (doi: 10.1111/ane.13215)

Gilroy, J., McInerny, C., Dudley, S., Balmer, D., Batty, C., French, P., Lees, A., Musgrove, A., Stoddart, A. (2020) British Ornithologists’ Union Records Committee (BOURC): 51st Report (January 2020) Ibis, 162, pp. 600-603. (doi: 10.1111/ibi.12817)

Flower, M., Lomeikaite, V., Holmans, P., Jones, L., Tabrizi, S. J., Monckton, D. G. (2020) Reply: The repeat variant in MSH3 is not a genetic modifier for spinocerebellar ataxia type 3 and Friedreich’s ataxia. Brain, 143, pp. e26. (doi: 10.1093/brain/awaa044)

Qüesta, J. I., Antoniou-Kourounioti, R. L., Rosa, S., Li, P., Duncan, S., Whittaker, C., Howard, M., Dean, C. (2020) Noncoding SNPs influence a distinct phase of Polycomb silencing to destabilize long-term epigenetic memory at Arabidopsis FLC. Genes and Development, 34, pp. 446-461. (doi: 10.1101/gad.333245.119)

Voigt, S., Sterz, K. R., Giehler, F., Mohr, A.-W., Wilson, J. B., Moosmann, A., Kieser, A. (2020) A central role of IKK2 and TPL2 in JNK activation and viral B-cell transformation. Nature Communications, 11, (doi: 10.1038/s41467-020-14502-x)

Ballester‐Lopez, A., Koehorst, E., Almendrote, M., Martínez‐Piñeiro, A., Lucente, G., Linares‐Pardo, I., Núñez‐Manchón, J., Guanyabens, N., Cano, A., Lucia, A., Overend, G., Cumming, S. A., Monckton, D. G., Casadevall, T., Isern, I., Sánchez‐Ojanguren, J., Planas, A., Rodríguez‐Palmero, A., Monlleó‐Neila, L., Pintos‐Morell, G., Ramos‐Fransi, A., Coll‐Cantí, J., Nogales‐Gadea, G. (2020) A DM1 family with interruptions associated with atypical symptoms and late onset but not with a milder phenotype. Human Mutation, 41, pp. 420-431. (doi: 10.1002/humu.23932)

Strawbridge, R. J., Ward, J., Bailey, M. E.S., Cullen, B., Ferguson, A., Graham, N., Johnston, K. J.A., Lyall, L. M., Pearsall, R., Pell, J., Shaw, R. J., Tank, R., Lyall, D. M., Smith, D. J. (2020) Carotid intima-media thickness: novel loci, sex-specific effects, and genetic correlations with obesity and glucometabolic traits in UK Biobank. Arteriosclerosis, Thrombosis, and Vascular Biology, 40, pp. 446-461. (doi: 10.1161/ATVBAHA.119.313226)

Cohen, E., Sawyer, J. K., Peterson, N. G., Dow, J. A.T., Fox, D. T. (2020) Physiology, development, and disease modeling in the Drosophila excretory system. Genetics, 214, pp. 235-264. (doi: 10.1534/genetics.119.302289)

Cabrero, P., Terhzaz, S., Dornan, A. J., Ghimire, S., Holmes, H. L., Turin, D. R., Romero, M. F., Davies, S., Dow, J. A.T. (2020) Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule. Proceedings of the National Academy of Sciences of the United States of America, 117, pp. 1779-1787. (doi: 10.1073/pnas.1915943117)

Shahzad, Z., Eaglesfield, R., Carr, C., Amtmann, A. (2020) Cryptic variation in RNA-directed DNA-methylation controls lateral root development when auxin signaling is perturbed. Nature Communications, 11, (doi: 10.1038/s41467-019-13927-3)

Harrop, A., Gilroy, J., McInerny, C., Dudley, S., Balmer, D., Batty, C., French, P., Lees, A., Musgrove, A., Stoddart, A. (2020) British Ornithologists’ Union Records Committee ( BOURC ): 50th Report (October 2019) Ibis, 162, pp. 263-268. (doi: 10.1111/ibi.12762)

Battle, M. W., Jones, M. A. (2020) Cryptochromes integrate green light signals into the circadian system. Plant, Cell and Environment, 43, pp. 16-27. (doi: 10.1111/pce.13643)

Horaruang, W., Hills, A., Blatt, M. R. (2020) Communication between the plasma membrane and tonoplast is an emergent property of ion transport. Plant Physiology, 182, pp. 1833-1835. (doi: 10.1104/pp.19.01485)

2019

van der Woude, L. C., Perrella, G., Snoek, B. L., van Hoogdalem, M., Novák, O., van Verk, M. C., van Kooten, H. N., Zorn, L. E., Tonckens, R., Dongus, J. A., Praat, M., Stouten, E. A., Proveniers, M. C. G., Vellutini, E., Patitaki, E., Shapulatov, U., Kohlen, W., Balasubramanian, S., Ljung, K., van der Krol, A. R., Smeekens, S., Kaiserli, E., van Zanten, M. (2019) HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion. Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 25343-25354. (doi: 10.1073/pnas.1911694116)

Ward, J., Lyall, L. M., Bethlehem, R. A.I., Ferguson, A., Strawbridge, R., Lyall, D. M., Cullen, B., Graham, N., Johnston, K. J.A., Bailey, M. E.S., Murray, G. K., Smith, D. J. (2019) Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure. Translational Psychiatry, 9, (doi: 10.1038/s41398-019-0635-y)

Olorunniji, F. J., Lawson-Williams, M., McPherson, A. L., Paget, J. E., Stark, W. M., Rosser, S. J. (2019) Control of ϕC31 integrase-mediated site-specific recombination by protein trans-splicing. Nucleic Acids Research, 47, pp. 11452-11460. (doi: 10.1093/nar/gkz936)

Gray, A., Capewell, P., Loney, C., Katzer, F., Shiels, B. R., Weir, W. (2019) Sheep as host species for zoonotic Babesia venatorum, United Kingdom. Emerging Infectious Diseases, 25, pp. 2257-2260. (doi: 10.3201/eid2512.190459)

Johnston, K. J.A., Adams, M. J., Nicholl, B. I., Ward, J., Strawbridge, R., McIntosh, A., Smith, D. J., Bailey, M. E.S. (2019) Identification of novel common variants associated with chronic pain using conditional false discovery rate analysis with major depressive disorder and assessment of pleiotropic effects of LRFN5. Translational Psychiatry, 9, (doi: 10.1038/s41398-019-0613-4)

Waghmare, S., Lefoulon, C., Zhang, B., Lileikyte, E., Donald, N., Blatt, M. (2019) K+ channel and SEC11 binding exchange regulates SNARE assembly for secretory traffic. Plant Physiology, 181, pp. 1096-1113. (doi: 10.1104/pp.19.00919)

Zhdanov, O., Busse, A., Cammarano, A., Zare-Behtash, H., Blatt, M. (2019) Effect of Wind on Morphology and Mechanical Properties of Arabidopsis Thaliana.

Ghimire, S., Terhzaz, S., Cabrero, P., Romero, M. F., Davies, S., Dow, J. A.T. (2019) Targeted renal knockdown of Na+/H+ exchanger regulatory factor Sip1 produces uric acid nephrolithiasis in Drosophila. American Journal of Physiology: Renal Physiology, 317, pp. F930-F940. (doi: 10.1152/ajprenal.00551.2018)

Ciosi, M., Maxwell, A., Cumming, S. A., Hensman Moss, D. J., Alshammari, A. M., Flower, M. D., Durr, A., Leavitt, B. R., Roos, R. A.C., Holmans, P., Jones, L., Langbehn, D. R., Kwak, S., Tabrizi, S. J., Monckton, D. G. (2019) A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes. EBioMedicine, 48, pp. 568-580. (doi: 10.1016/j.ebiom.2019.09.020)

Sharma, A., Sharma, B., Hayes, S., Kerner, K., Hoecker, U., Jenkins, G. I., Franklin, K. A. (2019) UVR8 disrupts stabilisation of PIF5 by COP1 to inhibit plant stem elongation in sunlight. Nature Communications, 10, (doi: 10.1038/s41467-019-12369-1)

van der Plas, E., Hamilton, M. J., Miller, J. N., Koscik, T. R., Long, J. D., Cumming, S., Povilaikaite, J., Farrugia, M. E., McLean, J., Jampana, R., Magnotta, V. A., Gutmann, L., Monckton, D. G., Nopoulos, P. C. (2019) Brain structural features of myotonic dystrophy type 1 and their relationship with CTG repeats. Journal of Neuromuscular Diseases, 6, pp. 321-332. (doi: 10.3233/jnd-190397)

Cumming, S. A., Jimenez-Moreno, C., Okkersen, K., Wenninger, S., Daidj, F., Hogarth, F., Littleford, R., Gorman, G., Bassez, G., Schoser, B., Lochmüller, H., van Engelen, B. G.M., Monckton, D. G. (2019) Genetic determinants of disease severity in the myotonic dystrophy type 1 OPTIMISTIC cohort. Neurology, 93, pp. e995-e1009. (doi: 10.1212/WNL.0000000000008056)

Jurić, I., Hibberd, J. M., Blatt, M., Burroughs, N. J. (2019) Computational modelling predicts substantial carbon assimilation gains for C3 plants with a single-celled C4 biochemical pump. PLoS Computational Biology, 15, (doi: 10.1371/journal.pcbi.1007373)

Lee, J.-M. et al. (2019) CAG repeat not polyglutamine length determines timing of Huntington’s disease onset. Cell, 178, pp. 887-900.e14. (doi: 10.1016/j.cell.2019.06.036)

Gray, S., Celis-Morales, C. A., Lyall, D. M., Petermann, F., Anderson, J., Ward, J., Iliodromiti, S., Mackay, D. F., Welsh, P., Bailey, M. E.S., Pell, J., Sattar, N., Gill, J. M.R., Gray, S. R. (2019) Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study. International Journal of Obesity, 43, pp. 1526-1538. (doi: 10.1038/s41366-019-0381-5)

Latham, B., Poyade, M., Finlay, C., Edmond, A., McVey, M. (2019) New tools in education: development and learning effectiveness of a computer application for use in a university biology curriculum. Springer Nature

Dobson, A. J., Boulton-McDonald, R., Houchou, L., Svermova, T., Ren, Z., Subrini, J., Vazquez-Prada, M., Hoti, M., Rodriguez-Lopez, M., Ibrahim, R., Gregoriou, A., Gkantiragas, A., Bähler, J., Ezcurra, M., Alic, N. (2019) Longevity is determined by ETS transcription factors in multiple tissues and diverse species. PLoS Genetics, 15, (doi: 10.1371/journal.pgen.1008212)

Caceres, C., Spatharis, S., Kaiserli, E., Smeti, E., Flowers, H., Bonachela, J. A. (2019) Temporal phosphate gradients reveal diverse acclimation responses in phytoplankton phosphate uptake. ISME Journal, 13, pp. 2834-2845. (doi: 10.1038/s41396-019-0473-1)

Overend, G., Légaré, C., Mathieu, J., Bouchard, L., Gagnon, C., Monckton, D. G. (2019) Allele length of the DMPK CTG repeat is a predictor of progressive myotonic dystrophy type 1 phenotypes. Human Molecular Genetics, 28, pp. 2245-2254. (doi: 10.1093/hmg/ddz055)

O'Hara, A., Headland, L. R., Díaz-Ramos, L. A., Morales, L. O., Strid, Å., Jenkins, G. I. (2019) Regulation of Arabidopsis gene expression by low fluence rate UV-B independently of UVR8 and stress signaling. Photochemical and Photobiological Sciences, 18, pp. 1675-1684. (doi: 10.1039/C9PP00151D)

Flower, M., Lomeikaite, V., Ciosi, M., Cumming, S., Morales, F., Lo, K., Hensman Moss, D., Jones, L., Holmans, P., Monckton, D. G., Tabrizi, S. J. (2019) MSH3 modifies somatic instability and disease severity in Huntington's and myotonic dystrophy type 1. Brain, 142, pp. 1876-1886. (doi: 10.1093/brain/awz115)

Kaboré, J. W., Camara, O., Ilboudo, H., Capewell, P., Clucas, C., Cooper, A., Kaboré, J., Camara, M., Jamonneau, V., Hertz-Fowler, C., Bélem, A. M. G., Matovu, E., Macleod, A., Sidibé, I., Noyes, H., Bucheton, B. (2019) Macrophage migrating inhibitory factor expression is associated with Trypanosoma brucei gambiense infection and is controlled by trans-acting expression quantitative trait loci in the Guinean population. Infection, Genetics and Evolution, 71, pp. 108-115. (doi: 10.1016/j.meegid.2019.03.021)

Barker, D., Plaisier, H., Bain, S. A., Attwood, T. K. (2019) Bioinformatics: the power of computers in biology – a practical guide. F1000Research, 8, (doi: 10.7490/f1000research.1116842.1)

Gao, H., Murugesan, B., Hoßbach, J., Evans, S. K., Stark, W. M., Smith, M. C.M. (2019) Integrating vectors for genetic studies in the rare Actinomycete Amycolatopsis marina. BMC Biotechnology, 19, (doi: 10.1186/s12896-019-0521-y)

Alford, L., Marley, R., Dornan, A., Dow, J. A.T., Nachman, R. J., Davies, S. A. (2019) Desiccation, thermal stress and associated mortality in Drosophila fruit flies induced by neuropeptide analogue treatment. Journal of Pest Science, 92, pp. 1123-1137. (doi: 10.1007/s10340-019-01100-0)

Alford, L., Marley, R., Dornan, A., Pierre, J.-S., Dow, J. A.T., Nachman, R. J., Davies, S. A. (2019) Assessment of neuropeptide binding sites and the impact of biostable kinin and CAP2b analogue treatment on aphid (Myzus persicae and Macrosiphum rosae) stress tolerance. Pest Management Science, 75, pp. 1750-1759. (doi: 10.1002/ps.5372)

Johnston, K. J.A., Adams, M. J., Nicholl, B. I., Ward, J., Strawbridge, R., Ferguson, A., McIntosh, A., Bailey, M. E.S., Smith, D. J. (2019) Genome-wide association study of multisite chronic pain in UK Biobank. PLoS Genetics, 15, (doi: 10.1371/journal.pgen.1008164)

Heskamp, L., van Nimwegen, M., Ploegmakers, M. J., Bassez, G., Deux, J.-F., Cumming, S. A., Monckton, D. G., van Engelen, B. G.M., Heerschap, A. (2019) Lower extremity muscle pathology in myotonic dystrophy type 1 assessed by quantitative MRI. Neurology, 92, pp. e2803-e2814. (doi: 10.1212/WNL.0000000000007648)

Légaré, C., Overend, G., Guay, S.-P., Monckton, D. G., Mathieu, J., Gagnon, C., Bouchard, L. (2019) gene DNA methylation levels are associated with muscular and respiratory profiles in DM1. Neurology Genetics, 5, (doi: 10.1212/NXG.0000000000000338)

Morris, J., Bailey, M. E.S., Baldassarre, D., Cullen, B., de Faire, U., Ferguson, A., Gigante, B., Giral, P., Goel, A., Graham, N., Hamsten, A., Humphries, S. E., Johnston, K. J.A., Lyall, D. M., Lyall, L. M., Sennblad, B., Silveira, A., Smit, A. J., Tremoli, E., Veglia, F., Ward, J., Watkins, H., Smith, D. J., Strawbridge, R. J. (2019) Genetic variation in CADM2 as a link between psychological traits and obesity. Scientific Reports, 9, (doi: 10.1038/s41598-019-43861-9)

Corrales, E., Vásquez, M., Zhang, B., Santamaría-Ulloa, C., Cuenca, P., Krahe, R., Monckton, D. G., Morales, F. (2019) Analysis of mutational dynamics at the DMPK (CTG)n locus identifies saliva as a suitable DNA sample source for genetic analysis in myotonic dystrophy type 1. PLoS ONE, 14, (doi: 10.1371/journal.pone.0216407)

Zhao, J., Pokhilko, A., Ebenhöh, O., Rosser, S. J., Colloms, S. D. (2019) A single-input binary counting module based on serine integrase site-specific recombination. Nucleic Acids Research, 47, pp. 4896-4909. (doi: 10.1093/nar/gkz245)

Zhang, B., Karnik, R., Alvim, J., Donald, N., Blatt, M. R. (2019) Dual sites for SEC11 on the SNARE SYP121 implicate a binding exchange during secretory traffic. Plant Physiology, 180, pp. 228-239. (doi: 10.1104/pp.18.01315)

Rühl, J., Citterio, C., Engelmann, C., Haigh, T., Dzionek, A., Dreyer, J., Khanna, R., Taylor, G. S., Wilson, J. B., Leung, C. S., Munz, C. (2019) Heterologous prime-boost vaccination protects against EBV antigen–expressing lymphomas. Journal of Clinical Investigation, 129, pp. 2071-2087. (doi: 10.1172/JCI125364)

Martinez Corrales, G., Cabrero, P., Dow, J. A.T., Terhzaz, S., Davies, S. (2019) Novel roles for GATAe in growth, maintenance and proliferation of cell populations in the Drosophila renal tubule. Development, 146, (doi: 10.1242/dev.178087)

Monckton, D. G. (2019) Manage risk of accidental gene editing of germline. Nature, 568, pp. 458. (doi: 10.1038/d41586-019-01284-6)

Landfeldt, E., Nikolenko, N., Jimenez-Moreno, C., Cumming, S., Monckton, D. G., Gorman, G., Turner, C., Lochmüller, H. (2019) Disease burden of myotonic dystrophy type 1. Journal of Neurology, 266, pp. 998-1006. (doi: 10.1007/s00415-019-09228-w)

Wilkinson, C. M., Roughley, M., Moffat, R. D., Monckton, D. G., MacGregor, M. (2019) In search of Robert Bruce, part I: craniofacial analysis of the skull excavated at Dunfermline in 1819. Journal of Archaeological Science: Reports, 24, pp. 556-564. (doi: 10.1016/j.jasrep.2019.02.018)

Ji, H., Wang, S., Cheng, C., Li, R., Wang, Z., Jenkins, G. I., Kong, F., Li, X. (2019) The RCC 1 family protein SAB 1 negatively regulates ABI 5 through multidimensional mechanisms during postgermination in Arabidopsis. New Phytologist, 222, pp. 907-922. (doi: 10.1111/nph.15653)

Celis-Morales, C. A., Lyall, D. M., Bailey, M. E.S., Petermann-Rocha, F., Anderson, J., Ward, J., Mackay, D. F., Welsh, P., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R. (2019) The combination of physical activity and sedentary behaviors modifies the genetic predisposition to obesity. Obesity, 27, pp. 653-661. (doi: 10.1002/oby.22417)

Papanatsiou, M., Petersen, J., Henderson, L., Wang, Y., Christie, J.M., Blatt, M.R. (2019) Optogenetic manipulation of stomatal kinetics improves carbon assimilation, water use, and growth. Science, 363, pp. 1456-1459. (doi: 10.1126/science.aaw0046)

Strawbridge, R. J., Ward, J., Ferguson, A., Graham, N., Shaw, R. J., Cullen, B., Pearsall, R., Lyall, L. M., Johnston, K. J.A., Niedzwiedz, C. L., Pell, J. P., Mackay, D., Langan-Martin, J., Lyall, D. M., Bailey, M. E.S., Smith, D. J. (2019) Identification of novel genome-wide associations for suicidality in UK Biobank, genetic correlation with psychiatric disorders and polygenic association with completed suicide. EBioMedicine, 41, pp. 517-525. (doi: 10.1016/j.ebiom.2019.02.005)

Jones, M. A. (2019) Retrograde signalling as an informant of circadian timing. New Phytologist, 221, pp. 1749-1753. (doi: 10.1111/nph.15525)

Conte, E., Mende, L., Grainge, I., Colloms, S. D. (2019) A mini-ISY100 transposon delivery system effective in γ proteobacteria. Frontiers in Microbiology, 10, (doi: 10.3389/fmicb.2019.00280)

Zhao, C. et al. (2019) Evolution of chloroplast retrograde signaling facilitates green plant adaptation to land. Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 5015-5020. (doi: 10.1073/pnas.1812092116)

Liao, X., Zhang, B., Blatt, M. R., Jenkins, G. I. (2019) A FRET method for investigating dimer/monomer status and conformation of the UVR8 photoreceptor. Photochemical and Photobiological Sciences, 18, pp. 367-374. (doi: 10.1039/C8PP00489G)

Jones, M. A., Morohashi, K., Grotewold, E., Harmer, S. L. (2019) Arabidopsis JMJD5/JMJ30 acts independently of LUX ARRHYTHMO within the plant circadian clock to enable temperature compensation. Frontiers in Plant Science, 10, (doi: 10.3389/fpls.2019.00057)

Landry, G. M., Furrow, E., Holmes, H. L., Hirata, T., Kato, A., Williams, P., Strohmaier, K., Gallo, C. J. R., Chang, M., Pandey, M. K., Jiang, H., Bansal, A., Franz, M.-C., Montalbetti, N., Alexander, M. P., Cabrero, P., Dow, J. A.T., DeGrado, T. R., Romero, M. F. (2019) Cloning, function, and localization of human, canine, and Drosophila ZIP10 (SLC39A10), a Zn2+ transporter. American Journal of Physiology: Renal Physiology, 316, pp. F263-F273. (doi: 10.1152/ajprenal.00573.2017)

Camacho, I. S., Theisen, A., Johannissen, L. O., Díaz-Ramos, L. A., Christie, J. M., Jenkins, G. I., Bellina, B., Barran, P., Jones, A. R. (2019) Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor. Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 1116-1125. (doi: 10.1073/pnas.1813254116)

Robson, T. M., Aphalo, P. J., Banaś, A. K., Barnes, P. W., Brelsford, C. C., Jenkins, G. I., Kotilainen, T. K., Łabuz, J., Martínez-Abaigar, J., Morales, L. O., Neugart, S., Pieristè, M., Rai, N., Vandenbussche, F., Jansen, M. A. K. (2019) A perspective on ecologically relevant plant-UV research and its practical application. Photochemical and Photobiological Sciences, 18, pp. 970-988. (doi: 10.1039/c8pp00526e)

Capewell, P., Atkins, K., Weir, W., Jamonneau, V., Camara, M., Clucas, C., Swar, N.-R. K., Ngoyi, D. M., Rotureau, B., Garside, P., Galvani, A. P., Bucheton, B., MacLeod, A. (2019) Resolving the apparent transmission paradox of African sleeping sickness. PLoS Biology, 17, (doi: 10.1371/journal.pbio.3000105)

Dow, J. A.T., Halberg, K. A., Terhzaz, S., Davies, S. A. (2019) Drosophila as a model for neuroendocrine control of renal homeostasis. Wiley

Davies, S.-A., Cabrero, P., Marley, R., Martinez-Corrales, G., Ghimire, S., Dornan, A. J., Dow, J. A.T. (2019) Epithelial function in the Drosophila Malpighian tubule: an in vivo renal model. Humana Press

Rezig, I. M., Bremner, S. K., Bhutta, M. S., Salt, I. P., Gould, G. W., McInerny, C. J. (2019) Genetic and cytological methods to study ESCRT cell cycle function in fission yeast. Humana Press

Simon, N. M.L., Litthauer, S., Jones, M. A., Dodd, A. N. (2019) Interactions between circadian rhythms, ROS and redox. Springer

van Dorst, M., Okkersen, K., Kessels, R. P.C., Meijer, F. J.A., Monckton, D. G., van Engelen, B. G.M., Tuladhar, A. M., Raaphorst, J. (2019) Structural white matter networks in myotonic dystrophy type 1. NeuroImage: Clinical, 21, (doi: 10.1016/j.nicl.2018.101615)

2018

Antoniou-Kourounioti, R. L., Hepworth, J., Heckmann, A., Duncan, S., Qüesta, J., Rosa, S., Säll, T., Holm, S., Dean, C., Howard, M. (2018) Temperature sensing is distributed throughout the regulatory network that controls FLC epigenetic silencing in vernalization. Cell Systems, 7, pp. 643-655.e9. (doi: 10.1016/j.cels.2018.10.011)

Jackson, M., Marks, L., May, G. H.W., Wilson, J. B. (2018) The genetic basis of disease. Essays In Biochemistry, 62, pp. 643-723. (doi: 10.1042/EBC20170053)

Rahmadi, R., Groot, P., van Rijn, M. H., van den Brand, J. A., Heins, M., Knoop, H., Heskes, T., OPTIMISTIC Consortium, (2018) Causality on longitudinal data: Stable specification search in constrained structural equation modeling. Statistical Methods in Medical Research, 27, pp. 3814-3834. (doi: 10.1177/0962280217713347)

Ashizawa, T. et al. (2018) Consensus-based care recommendations for adults with myotonic dystrophy type 1. Neurology: Clinical Practice, 8, pp. 507-520. (doi: 10.1212/CPJ.0000000000000531)

Waghmare, S., Lileikyte, E., Karnik, R., Goodman, J. K., Blatt, M. R., Jones, A. M.E. (2018) SNAREs SYP121 and SYP122 mediate the secretion of distinct cargo subsets. Plant Physiology, 178, pp. 1679-1688. (doi: 10.1104/pp.18.00832)

Channumsin, M., Ciosi, M., Masiga, D., Turner, C. M. R., Mable, B. K. (2018) Sodalis glossinidius presence in wild tsetse is only associated with presence of trypanosomes in complex interactions with other tsetse-specific factors. BMC Microbiology, 18, (doi: 10.1186/s12866-018-1285-6)

Madsen, M. A., Semerdzhiev, S., Amtmann, A., Tonon, T. (2018) Engineering mannitol biosynthesis in Escherichia coli and Synechococcus sp. PCC 7002 using a green algal fusion protein. ACS Synthetic Biology, 7, pp. 2833-2840. (doi: 10.1021/acssynbio.8b00238)

Cumming, S. A., Hamilton, M. J., Robb, Y., Gregory, H., McWilliam, C., Cooper, A., Adam, B., McGhie, J., Hamilton, G., Herzyk, P., Tschannen, M. R., Worthey, E., Petty, R., Ballantyne, B., The Scottish Myotonic Dystrophy Consortium, , Warner, J., Farrugia, M. E., Longman, C., Monckton, D. G. (2018) De novo repeat interruptions are associated with reduced somatic instability and mild or absent clinical features in myotonic dystrophy type 1. European Journal of Human Genetics, 26, pp. 1635-1647. (doi: 10.1038/s41431-018-0156-9)

Lefoulon, C., Waghmare, S., Karnik, R., Blatt, M. R. (2018) Gating control and K+ uptake by the KAT1 K+ channel leaveraged through membrane anchoring of the trafficking protein SYP121. Plant, Cell and Environment, 41, pp. 2668-2677. (doi: 10.1111/pce.13392)

Hamilton, M. J., McLean, J., Cumming, S., Ballantyne, B., McGhie, J., Jampana, R., Longman, C., Evans, J. J., Monckton, D. G., Farrugia, M. E. (2018) Outcome measures for central nervous system evaluation in myotonic dystrophy type 1 may be confounded by deficits in motor function or insight. Frontiers in Neurology, 9, (doi: 10.3389/fneur.2018.00780)

Harrop, A., McInerny, C., McGowan, B., Naylor, K., Owen, A. (2018) British Ornithologists’ Union Records Committee (BOURC): 49th Report (October 2018) Ibis, 160, pp. 936-942. (doi: 10.1111/ibi.12654)

Davis, J. L., Armengaud, P., Larson, T. R., Graham, I. A., White, P. J., Newton, A. C., Amtmann, A. (2018) Contrasting nutrient‐disease relationships: potassium gradients in barley leaves have opposite effects on two fungal pathogens with different sensitivities to jasmonic acid. Plant, Cell and Environment, 41, pp. 2357-2372. (doi: 10.1111/pce.13350)

Pandit, A. A., Ragionieri, L., Marley, R., Yeoh, J. G.C., Inward, D. J.G., Davies, S.-A., Predel, R., Dow, J. A.T. (2018) Coordinated RNA-Seq and peptidomics identify neuropeptides and G-protein coupled receptors (GPCRs) in the large pine weevil Hylobius abietis, a major forestry pest. Insect Biochemistry and Molecular Biology, 101, pp. 94-107. (doi: 10.1016/j.ibmb.2018.08.003)

Kaiserli, E., Perrella, G., Davidson, M. L.H. (2018) Light and temperature shape nuclear architecture and gene expression. Current Opinion in Plant Biology, 45, pp. 103-111. (doi: 10.1016/j.pbi.2018.05.018)

Wyse, C. A., Celis Morales, C. A., Ward, J., Lyall, D., Smith, D. J., Mackay, D., Curtis, A. M., Bailey, M. E., Biello, S., Gill, J. M.R., Pell, J.P. (2018) Population-level seasonality in cardiovascular mortality, blood pressure, BMI and inflammatory cells in UK Biobank. Annals of Medicine, 50, pp. 410-419. (doi: 10.1080/07853890.2018.1472389)

Levesley, J., Baine, F., Ciosi, M., Maxwell, A., Monckton, D. G., Krause, A. (2018) A CIS-acting Modifier of Age at Diagnosis of Huntington Disease in Black South African Patients.

Ging, H., Nethisinghe, S., Chatzi, A., Ciosi, M., Monckton, D. G., Giunti, P. (2018) Determining the CAG Repeat Mosaic in Post-mortem Human HD Brains.

Flower, M., Lomeikaite, V., Ciosi, M., Morales, F., Lo, K., Hensman Moss, D., Jones, L., Holmans, P., Tabrizi, S. J., Monckton, D. G. (2018) Genetic Variation in MSH3 That Lowers Its Expression Ameliorates Disease Course and Limits Repeat Expansion in Huntington’s Disease and Myotonic Dystrophy Type 1.

Ciosi, M., Maxwell, A., Cumming, S., Hensman Moss, D. J., Alshammari, A. M., Flower, M. D., Durr, A., Leavitt, B. R., Roos, R. A., TRACK-HD team, , ENROLL-HD team, , Holmans, P., Jones, L., Langbehn, D. R., Kwak, S., Tabrizi, S. J., Monckton, D. G. (2018) Glutamine Codon Usage and Somatic Mosaicism of the HTT CAG Repeat Are Modifiers of Huntington Disease Severity.

Strawbridge, R., Ward, J., Lyall, L. M., Turnbridge, E. M., Cullen, B., Graham, N., Ferguson, A., Johnston, K. J.A., Lyall, D. M., Mackay, D., Cavanagh, J., Howard, D. M., Adams, M. J., Deary, I., Escott-Price, V., O'Donovan, M., McIntosh, A. M., Bailey, M. E.S., Pell, J. P., Harrison, P. J., Smith, D. (2018) Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression. Translational Psychiatry, 8, (doi: 10.1038/s41398-018-0236-1)

Jones, M. A. (2018) Using light to improve commercial value. Horticulture Research, 5, (doi: 10.1038/s41438-018-0049-7)

Zhang, B., Karnik, R., Donald, N., Blatt, M. R. (2018) A GPI signal peptide-anchored split-ubiquitin (GPS) system for detecting soluble bait protein interactions at the membrane. Plant Physiology, 178, pp. 13-17. (doi: 10.1104/pp.18.00577)

Ferguson, A., Lyall, L. M., Ward, J., Strawbridge, R. J., Cullen, B., Graham, N., Niedzwiedz, C. L., Johnston, K. J.A., Mackay, D., Biello, S. M., Pell, J. P., Cavanagh, J., McIntosh, A. M., Doherty, A., Bailey, M. E.S., Lyall, D. M., Wyse, C. A., Smith, D. J. (2018) Genome-wide association study of circadian rhythmicity in 71,500 UK Biobank participants and polygenic association with mood instability. EBioMedicine, 35, pp. 279-287. (doi: 10.1016/j.ebiom.2018.08.004)

Boakye, D., Wyse, C.A., Morales-Celis, C.A., Biello, S.M., Bailey, M.E.S., Dare, S., Ward, J., Gill, J.M.R., Pell, J.P., Mackay, D.F. (2018) Tobacco exposure and sleep disturbance in 498 208 UK Biobank participants. Journal of Public Health, 40, pp. 517-526. (doi: 10.1093/pubmed/fdx102)

Okkersen, K., Jimenez-Moreno, C., Wenninger, S., Daidj, F., Glennon, J., Cumming, S., Littleford, R., Monckton, D. G., Lochmüller, H., Catt, M., Faber, C. G., Hapca, A., Donnan, P. T., Gorman, G., Bassez, G., Schoser, B., Knoop, H., Treweek, S., van Engelen, B. G. M. (2018) Cognitive behavioural therapy with optional graded exercise therapy in patients with severe fatigue with myotonic dystrophy type 1: a multicentre, single-blind, randomised trial. Lancet Neurology, 17, pp. 671-680. (doi: 10.1016/S1474-4422(18)30203-5)

Díaz-Ramos, L. A., O'Hara, A., Kanagarajan, S., Farkas, D., Strid, Å., Jenkins, G. I. (2018) Difference in the action spectra for UVR8 monomerisation and HY5 transcript accumulation in Arabidopsis. Photochemical and Photobiological Sciences, 17, pp. 1108-1117. (doi: 10.1039/C8PP00138C)

Shahzad, Z., Kellermeier, F., Armstrong, E. M., Rogers, S., Lobet, G., Amtmann, A., Hills, A. (2018) EZ-Root-VIS: A software pipeline for the rapid analysis and visual reconstruction of root system architecture. Plant Physiology, 177, pp. 1368-1381. (doi: 10.1104/pp.18.00217)

Ciosi, M., Cumming, S. A., Alshammari, A. M., Symeonidi, E., Herzyk, P., Mcguinness, D., Galbraith, J., Hamilton, G., Monckton, D. G. (2018) Library preparation and MiSeq sequencing for the genotyping-by-sequencing of the Huntington disease HTT exon one trinucleotide repeat and the quantification of somatic mosaicism [Protocol] (doi: 10.21203/rs.2.1581/v2)

Feroz, H., Ferlez, B., Lefoulon, C., Ren, T., Baker, C. S., Gajewski, J. P., Lugar, D. J., Gaudana, S. B., Butler, P. J., Hühn, J., Lamping, M., Parak, W. J., Hibberd, J. M., Kerfeld, C. A., Smirnoff, N., Blatt, M. R., Golbeck, J. H., Kumar, M. (2018) Light-driven chloride transport kinetics of halorhodopsin. Biophysical Journal, 115, pp. 353-360. (doi: 10.1016/j.bpj.2018.06.009)

Mugasa, C. M., Villinger, J., Gitau, J., Ndungu, N., Ciosi, M., Masiga, D. (2018) Morphological re-description and molecular identification of Tabanidae (Diptera) in East Africa. ZooKeys, 796, pp. 117-144. (doi: 10.3897/zookeys.769.21144)

Finlay, C. (2018) Keynote: Challenges to Student Success. Can Digital Approaches Help Overcome Them?

Trejo, C. S., Rock, R. S., Stark, W. M., Boocock, M. R., Rice, P. A. (2018) Snapshots of a molecular swivel in action. Nucleic Acids Research, 46, pp. 5286-5296. (doi: 10.1093/nar/gkx1309)

Lyall, L. M., Wyse, C. A., Graham, N., Ferguson, A., Lyall, D. M., Cullen, B., Celis Morales, C. A., Biello, S. M., Mackay, D., Ward, J., Strawbridge, R. J., Gill, J. M.R., Bailey, M. E.S., Pell, J. P., Smith, D. J. (2018) Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK Biobank. Lancet Psychiatry, 5, pp. 507-514. (doi: 10.1016/S2215-0366(18)30139-1)

Pokhilko, A., Ebenhöh, O., Stark, W. M., Colloms, S. D. (2018) Mathematical model of a serine integrase-controlled toggle switch with a single input. Journal of the Royal Society: Interface, 15, (doi: 10.1098/rsif.2018.0160)

Zhdanov, O., Busse, A., Blatt, M., Zare-Behtash, H. (2018) A specialised wind tunnel for investigation of ecophysiological response of plants to wind.

Perrella, G., Davidson, M. L.H., O'Donnell, L., Nastase, A.-M., Herzyk, P., Breton, G., Pruneda-Paz, J. L., Kay, S. A., Chory, J., Kaiserli, E. (2018) ZINC-FINGER interactions mediate transcriptional regulation of hypocotyl growth in Arabidopsis. Proceedings of the National Academy of Sciences of the United States of America, 115, pp. E4503-E4511. (doi: 10.1073/pnas.1718099115)

Armfield, K., Baillie, G., Wilson, J.B. (2018) Development of Therapeutic Approaches to Targeting Epstein-Barr virus Related Malignancies.

Alqarni, S., Wilson, J.B. (2018) Epstein-Barr Virus Nuclear Antigen-1, Action and Reaction as an Oncogene.

Wood, L. et al. (2018) 222nd ENMC International Workshop: Myotonic dystrophy, developing a European consortium for care and therapy, Naarden, The Netherlands, 1–2 July 2016. Neuromuscular Disorders, 28, pp. 463-469. (doi: 10.1016/j.nmd.2018.02.003)

Blatt, M. R. (2018) Concepts and techniques in plant membrane physiology. John Wiley & Sons, Ltd

Amtmann, A., Armengaud, P., Volkov, V. (2018) Potassium nutrition and salt stress. John Wiley & Sons, Ltd

Blatt, M.R., Thiel, G. (2018) SNARE components and mechanisms of exocytosis in plants. John Wiley & Sons, Ltd

Jenkins, G. I., Brown, B. A. (2018) UV-B perception and signal transduction. John Wiley & Sons, Ltd

Dobson, A. J., He, X., Blanc, E., Bolukbasi, E., Feseha, Y., Yang, M., Piper, M. D.W. (2018) Tissue-specific transcriptome profiling of Drosophila reveals roles for GATA transcription factors in longevity by dietary restriction. npj Aging and Mechanisms of Disease, 4, (doi: 10.1038/s41514-018-0024-4)

Wilson, J. B., Manet, E., Gruffat, H., Busson, P., Blondel, M., Fahraeus, R. (2018) EBNA1: oncogenic activity, immune evasion and biochemical functions provide targets for novel therapeutic strategies against Epstein-Barr virus-associated cancers. Cancers, 10, (doi: 10.3390/cancers10040109)

Terhzaz, S., Alford, L., Yeoh, J. G.C., Marley, R., Dornan, A. J., Dow, J. A.T., Davies, S. A. (2018) Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii. Pest Management Science, 74, pp. 800-810. (doi: 10.1002/ps.4663)

Lyall, L. M., Wyse, C. A., Celis Morales, C. A., Lyall, D. M., Cullen, B., Mackay, D., Ward, J., Graham, N., Strawbridge, R. J., Gill, J. M.R., Ferguson, A., Bailey, M. E.S., Pell, J. P., Curtis, A. M., Smith, D. J. (2018) Seasonality of depressive symptoms in women but not in men: a cross-sectional study in the UK Biobank cohort. Journal of Affective Disorders, 229, pp. 296-305. (doi: 10.1016/j.jad.2017.12.106)

Lombaert, E., Ciosi, M., Miller, N. J., Sappington, T. W., Blin, A., Guillemaud, T. (2018) Colonization history of the western corn rootworm (Diabrotica virgifera virgifera) in North America: insights from random forest ABC using microsatellite data. Biological Invasions, 20, pp. 665-677. (doi: 10.1007/s10530-017-1566-2)

Sannino, D. R., Dobson, A. J., Edwards, K., Angert, E. R., Buchon, N. (2018) The Drosophila melanogaster gut microbiota provisions thiamine to its host. mBio, 9, (doi: 10.1128/mBio.00155-18)

Litthauer, S., Chan, K. X., Jones, M. (2018) 3'-phosphoadenosine 5'-phosphate accumulation delays the circadian system. Plant Physiology, 176, pp. 3120-3135. (doi: 10.1104/pp.17.01611)

Kaiserli, E. (2018) Ultraviolet rays light up transcriptional networks regulating plant growth. Developmental Cell, 44, pp. 409-411. (doi: 10.1016/j.devcel.2018.02.005)

Fogg, P. C.M., Younger, E., Fernando, B. D., Khaleel, T., Stark, W. M., Smith, M. C.M. (2018) Recombination directionality factor gp3 binds ϕC31 integrase via the zinc domain, potentially affecting the trajectory of the coiled-coil motif. Nucleic Acids Research, 46, pp. 1308-1320. (doi: 10.1093/nar/gkx1233)

Hepworth, J., Antoniou-Kourounioti, R. L., Bloomer, R. H., Selga, C., Berggren, K., Cox, D., Collier Harris, B. R., Irwin, J. A., Holm, S., Säll, T., Howard, M., Dean, C. (2018) Absence of warmth permits epigenetic memory of winter in Arabidopsis. Nature Communications, 9, (doi: 10.1038/s41467-018-03065-7)

Strawbridge, R. J., Ward, J., Cullen, B., Turnbridge, E. M., Hartz, S., Bierut, L., Horton, A., Bailey, M. E.S., Graham, N., Ferguson, A., Lyall, D. M., Mackay, D., Pidgeon, L. M., Cavanagh, J., Pell, J. P., O’Donovan, M., Escott-Price, V., Harrison, P. J., Smith, D. J. (2018) Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort. Translational Psychiatry, 8, (doi: 10.1038/s41398-017-0079-1)

Soriano, G., Cloix, C., Heilmann, M., Núñez-Olivera, E., Martínez-Abaigar, J., Jenkins, G. I. (2018) Evolutionary conservation of structure and function of the UVR8 photoreceptor from the liverwort Marchantia polymorpha and the moss Physcomitrella patens. New Phytologist, 217, pp. 151-162. (doi: 10.1111/nph.14767)

Pantin, F., Blatt, M. R. (2018) Stomatal response to humidity: blurring the boundary between active and passive movement. Plant Physiology, 176, pp. 485-488. (doi: 10.1104/pp.17.01699)

AlQarni, S., Al-Sheikh, Y., Campbell, D., Drotar, M., Hannigan, A., Boyle, S., Herzyk, P., Kossenkov, A., Armfield, K., Jamieson, L., Bailo, M., Lieberman, P. M., Tsimbouri, P., Wilson, J. B. (2018) Lymphomas driven by Epstein-Barr virus nuclear antigen-1 (EBNA1) are dependant upon Mdm2. Oncogene, 37, pp. 3998-4012. (doi: 10.1038/s41388-018-0147-x)

Litthauer, S., Jones, M. A. (2018) SAL1-PAP retrograde signalling extends circadian period by reproducing the loss of exoribonuclease (XRN) activity. Plant Signaling and Behavior, 13,

2017

Filer, D., Thompson, M. A., Takhaveev, V., Dobson, A. J., Kotronaki, I., Green, J. W.M., Heinemann, M., Tullet, J. M.A., Alic, N. (2017) RNA polymerase III limits longevity downstream of TORC1. Nature, 552, pp. 263-267. (doi: 10.1038/nature25007)

Gnanasundram, S. V., Pyndiah, S., Daskalogianni, C., Armfield, K., Nylander, K., Wilson, J. B., Fåhraeus, R. (2017) PI3Kδ activates E2F1 synthesis in response to mRNA translation stress. Nature Communications, 8, (doi: 10.1038/s41467-017-02282-w)

Gao, X., Lampraki, E.-M., Al-Khalidi, S., Qureshi, M. A., Desai, R., Wilson, J. B. (2017) N-acetylcysteine (NAC) ameliorates Epstein-Barr virus latent membrane protein 1 induced chronic inflammation. PLoS ONE, 12, (doi: 10.1371/journal.pone.0189167)

Hector, R. D., Kalscheuer, V. M., Hennig, F., Leonard, H., Downs, J., Clarke, A., Benke, T. A., Armstrong, J., Pineda, M., Bailey, M. E.S., Cobb, S. R. (2017) CDKL5 variants: improving our understanding of a rare neurological disorder. Neurology Genetics, 3, (doi: 10.1212/NXG.0000000000000200)

Jones, M. A. (2017) Interplay of circadian rhythms and light in the regulation of photosynthesis-derived metabolism. Springer

Ward, J., Strawbridge, R. J., Bailey, M. E.S., Graham, N., Ferguson, A., Lyall, D. M., Cullen, B., Pidgeon, L. M., Cavanagh, J., Mackay, D. F., Pell, J. P., O'Donovan, M., Escott-Price, V., Smith, D. J. (2017) Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia. Translational Psychiatry, 7, (doi: 10.1038/s41398-017-0012-7)

Jenkins, G. I. (2017) Photomorphogenic responses to ultraviolet-B light. Plant, Cell and Environment, 40, pp. 2544-2557. (doi: 10.1111/pce.12934)

Wang, Y., Hills, A., Vialet-Chabrand, S., Papanatsiou, M., Griffiths, H., Rogers, S., Lawson, T., Lew, V. L., Blatt, M. R. (2017) Unexpected connections between humidity and ion transport discovered using a model to bridge guard cell-to-leaf scales. Plant Cell, 29, pp. 2921-2939. (doi: 10.1105/tpc.17.00694)

Leader, D. P., Krause, S. A., Pandit, A., Davies, S. A., Dow, J. A.T. (2017) FlyAtlas 2: a new version of the Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data. Nucleic Acids Research, 46, pp. D809-D815. (doi: 10.1093/nar/gkx976)

Larson, E. R., Van Zelm, E., Roux, C., Marion-Poll, A., Blatt, M. R. (2017) Clathrin Heavy Chain subunits coordinate endo- and exocytic traffic and affect stomatal movement. Plant Physiology, 175, pp. 708-720. (doi: 10.1104/pp.17.00970)

Shahzad, Z., Amtmann, A. (2017) Food for thought: how nutrients regulate root system architecture. Current Opinion in Plant Biology, 39, pp. 80-87. (doi: 10.1016/j.pbi.2017.06.008)

Dow, J. A.T. (2017) The essential roles of metal ions in insect homeostasis and physiology. Current Opinion in Insect Science, 23, pp. 43-50. (doi: 10.1016/j.cois.2017.07.001)

Bahey, N. G., Gadalla, K. K.E., McGonigal, R., Bailey, M. E.S., Edgar, J. M., Cobb, S. R. (2017) Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome. Neuroscience, 358, pp. 261-268. (doi: 10.1016/j.neuroscience.2017.06.061)

Szilagyi, Z., Banyai, G., Davila Lopez, M., McInerny, C. J., Gustafsson, C. M. (2017) Correction for Szilagyi et al., "Cyclin-Dependent Kinase 8 Regulates Mitotic Commitment in Fission Yeast" Molecular and Cellular Biology, 37, (doi: 10.1128/MCB.00262-17)

Okkersen, K., Monckton, D. G., Le, N., Tuladhar, A. M., Raaphorst, J., van Engelen, B. G.M. (2017) Brain imaging in myotonic dystrophy type 1: a systematic review. Neurology, 89, pp. 960-969. (doi: 10.1212/WNL.0000000000004300)

Olorunniji, F. J., McPherson, A. L., Rosser, S. J., Smith, M. C.M., Colloms, S. D., Stark, W. M. (2017) Control of serine integrase recombination directionality by fusion with the directionality factor. Nucleic Acids Research, 45, pp. 8635-8645. (doi: 10.1093/nar/gkx567)

Stark, W. M. (2017) Making serine integrases work for us. Current Opinion in Microbiology, 38, pp. 130-136. (doi: 10.1016/j.mib.2017.04.006)

Armfield, K., Wilson, J.B. (2017) Development of Therapeutic Approaches to Targeting EBV Related Disease.

Alqarni, S., Wilson, J.B. (2017) Epstein-Barr Virus Nuclear Antigen-1, Action and Reaction as an Oncogene.

Yeoh, J. G.C., Pandit, A. A., Zandawala, M., Nässel, D. R., Davies, S.-A., Dow, J. (2017) DINeR: Database for Insect Neuropeptide Research. Insect Biochemistry and Molecular Biology, 86, pp. 9-19. (doi: 10.1016/j.ibmb.2017.05.001)

Cai, S., Papanatsiou, M., Blatt, M. R., Chen, Z.-H. (2017) Speedy grass stomata: emerging molecular and evolutionary features. Molecular Plant, 10, pp. 912-914. (doi: 10.1016/j.molp.2017.06.002)

Gadalla, K. K.E., Vudhironarit, T., Hector, R. D., Sinnett, S., Bahey, N. G., Bailey, M. E.S., Gray, S. J., Cobb, S. R. (2017) Development of a novel AAV gene therapy cassette with improved safety features and efficacy in a mouse model of Rett syndrome. Molecular Therapy: Methods and Clinical Development, 5, pp. 180-190. (doi: 10.1016/j.omtm.2017.04.007)

Sinnett, S. E., Hector, R. D., Gadalla, K. K.E., Heindel, C., Chen, D., Zaric, V., Bailey, M. E.S., Cobb, S. R., Gray, S. J. (2017) Improved MECP2 gene therapy extends the survival of MeCP2-null mice without apparent toxicity after intracisternal delivery. Molecular Therapy: Methods and Clinical Development, 5, pp. 106-115. (doi: 10.1016/j.omtm.2017.04.006)

Riedelsberger, J., Blatt, M. R. (2017) Editorial: Roots—the hidden provider. Frontiers in Plant Science, 8, (doi: 10.3389/fpls.2017.01021)

Cai, S., Chen, G., Wang, Y., Huang, Y., Marchant, B., Wang, Y., Yang, Q., Dai, F., Hills, A., Franks, P. J., Nevo, E., Soltis, D., Soltis, P., Sessa, E., Wolf, P. G., Xue, D., Zhang, G., Pogson, B. J., Blatt, M. R., Chen, Z.-H. (2017) Evolutionary conservation of ABA signaling for stomatal closure in ferns. Plant Physiology, 174, pp. 732-747. (doi: 10.1104/pp.16.01848)

Vialet-Chabrand, S., Hills, A., Wang, Y., Griffiths, H., Lew, V. L., Lawson, T., Blatt, M. R., Rogers, S. (2017) Global sensitivity analysis of OnGuard models identifies key hubs for transport interaction in stomatal dynamics. Plant Physiology, 174, pp. 680-688. (doi: 10.1104/pp.17.00170)

Vialet-Chabrand, S. R.M., Matthews, J. S.A., McAusland, L., Blatt, M. R., Griffiths, H., Lawson, T. (2017) Temporal dynamics of stomatal behavior: modeling and implications for photosynthesis and water use. Plant Physiology, 174, pp. 603-613. (doi: 10.1104/pp.17.00125)

Jezek, M., Blatt, M. R. (2017) The membrane transport system of the guard cell and its integration for stomatal dynamics. Plant Physiology, 174, pp. 487-519. (doi: 10.1104/pp.16.01949)

McVey, M., Finlay, C. (2017) Development of the Online Course for Campus Based Students: Current Directions in Life Sciences.

Cooper, A., Ilboudo, H., Alibu, V. P., Ravel, S., Enyaru, J., Weir, W., Noyes, H., Capewell, P., Camara, M., Milet, J., Jamonneau, V., Camara, O., Matovu, E., Bucheton, B., MacLeod, A. (2017) APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis. eLife, 6, (doi: 10.7554/eLife.25461)

Griffiths, M., Finlay, C. (2017) Expanding Induction and Using the VLE to Enhance Induction to First-year Life Sciences.

Ballance, D., Browitt, A., Finlay, C., Griffiths, M., Rinaldi, C. (2017) What Works: Student Retention and Success Institutional Report.

Amtmann, A., Shahzad, Z. (2017) To respond or not to respond? Natural variation of root architectural responses to nutrient signals. Journal of Experimental Botany, 68, pp. 2636-2640. (doi: 10.1093/jxb/erx160)

Gomes-Pereira, M., Monckton, D. G. (2017) Ethidium bromide modifies the agarose electrophoretic mobility of CAG•CTG alternative DNA structures generated by PCR. Frontiers in Cellular Neuroscience, 11, (doi: 10.3389/fncel.2017.00153)

Wood, L., Cordts, I., Atalaia, A., Marini-Bettolo, C., Maddison, P., Phillips, M., Roberts, M., Hammans, S., Straub, V., Petty, R., Orrell, R., Monckton, D. G., Nikolenko, N., Jimenez-Moreno, A.-C., Thompson, R., Hilton-Jones, D., Turner, C., Lochmüller, H. (2017) The UK myotonic dystrophy patient registry: facilitating and accelerating clinical research. Journal of Neurology, 264, pp. 979-988. (doi: 10.1007/s00415-017-8483-2)

Alqarni, S., Wilson, J.B. (2017) Epstein-Barr Virus Nuclear Antigen-1, in a Preclinical Model for BL.

Armfield, K., Wilson, J.B. (2017) Therapeutic Approaches to Targeting EBV Related Disease.

Papanatsiou, M., Amtmann, A., Blatt, M. R. (2017) Stomatal clustering in Begonia associates with the kinetics of leaf gaseous exchange and influences water use efficiency. Journal of Experimental Botany, 68, pp. 2309-2315. (doi: 10.1093/jxb/erx072)

DiPaolo, G., Jimenez-Moreno, C., Nikolenko, N., Atalaia, A., Monckton, D. G., Guglieri, M., Lochmüller, H. (2017) Functional impairment in patients with myotonic dystrophy type 1 can be assessed by an ataxia rating scale (SARA) Journal of Neurology, 264, pp. 701-708. (doi: 10.1007/s00415-017-8399-x)

Celis-Morales, C., Lyall, D. M., Guo, Y., Steell, L., Llamas, D., Ward, J., Mackay, D. F., Biello, S. M., Bailey, M. E.S., Pell, J. P., Gill, J. M.R. (2017) Sleep characteristics modify the association between genetic predisposition to obesity and anthropometric measurements in 119,679 UK Biobank participants. American Journal of Clinical Nutrition, 105, pp. 980-990. (doi: 10.3945/ajcn.116.147231)

Browitt, A., Ballance, D., Rinaldi, C., Finlay, C., Griffiths, M. (2017) Enhancing the Student Journey: Supporting Student Retention and Success.

Hamilton, M., Robb, Y., Cumming, S., Gregory, H., Duncan, A., Rahman, M., McKeown, A., McWilliam, C., Dean, J., Wilcox, A., Farrugia, M. E., Cooper, A., McGhie, J., Adam, B., Petty, R., Longman, C., Findlay, I., Japp, A., Monckton, D. C., Denvir, M. A. (2017) Elevated plasma levels of cardiac troponin-I predict left ventricular systolic dysfunction in patients with myotonic dystrophy type 1: a multicentre cohort follow-up study. PLoS ONE, 12, (doi: 10.1371/journal.pone.0174166)

Hector, R. D., Dando, O., Ritakari, T. E., Kind, P. C., Bailey, M. E.S., Cobb, S. R. (2017) Characterisation of Cdkl5 transcript isoforms in rat. Gene, 603, pp. 21-26. (doi: 10.1016/j.gene.2016.12.001)

Rahmadi, R., Groot, P., Heins, M., Knoop, H., Heskes, T., OPTIMISM Consortium, (2017) Causality on cross-sectional data: Stable specification search in constrained structural equation modeling. Applied Soft Computing, 52, pp. 687-698. (doi: 10.1016/j.asoc.2016.10.003)

Fogg, P. C.M., Haley, J. A., Stark, W. M., Smith, M. C.M. (2017) Genome integration and excision by a new Streptomyces Bacteriophage ϕJoe. Applied and Environmental Microbiology, 83, (doi: 10.1128/AEM.02767-16)

Gianfagna, F., Grippi, C., Ahrens, W., Bailey, M. E.S., Börnhorst, C., De Henauw, S., Foraita, R., Koni, A. C., Krogh, V., Mårild, S., Molnár, D., Moreno, L., Pitsiladis, Y., Russo, P., Siani, A., Tornaritis, M., Veidebaum, T., Iacoviello, L. (2017) The role of neuromedin U in adiposity regulation. Haplotype analysis in European children from the IDEFICS Cohort. PLoS ONE, 12, (doi: 10.1371/journal.pone.0172698)

Dobson, A. J., Chaston, J. M., Douglas, A. E. (2017) Erratum to: The Drosophila transcriptional network is structured by microbiota. BMC Genomics, 18, (doi: 10.1186/s12864-017-3508-x)

Deschamps, T., Quentin, B., Leske, D. M., MacLeod, R., Mompelat, D., Tafforeau, L., Lotteau, V., Maréchal, V., Baillie, G. S., Gruffat, H., Wilson, J. B., Manet, E. (2017) Epstein-Barr virus nuclear antigen 1 interacts with regulator of chromosome condensation 1 dynamically throughout the cell cycle. Journal of General Virology, 98, pp. 251-265. (doi: 10.1099/jgv.0.000681)

Botta, A., Rossi, G., Marcaurelio, M., Fontana, L., D'Apice, M. R., Brancati, F., Massa, R., Monckton, D. G., Sangiuolo, F., Novelli, G. (2017) Identification and characterization of 5' CCG interruptions in complex DMPK expanded alleles. European Journal of Human Genetics, 25, pp. 257-261. (doi: 10.1038/ejhg.2016.148)

Chen, Z.-H., Chen, G., Dai, F., Wang, Y., Hills, A., Ruan, Y.-L., Zhang, G., Franks, P. J., Nevo, E., Blatt, M. R. (2017) Molecular evolution of grass stomata. Trends in Plant Science, 22, pp. 124-139. (doi: 10.1016/j.tplants.2016.09.005)

Dobson, A. J., Ezcurra, M., Flanagan, C. E., Summerfield, A. C., Piper, M. D.W., Gems, D., Alic, N. (2017) Nutritional programming of lifespan by FOXO inhibition on sugar-rich diets. Cell Reports, 18, pp. 299-306. (doi: 10.1016/j.celrep.2016.12.029)

Hayes, S., Sharma, A., Fraser, D. P., Trevisan, M., Cragg-Barber, C. K., Tavridou, E., Fankhauser, C., Jenkins, G. I., Franklin, K. A. (2017) UV-B perceived by the UVR8 photoreceptor inhibits plant thermomorphogenesis. Current Biology, 27, pp. 120-127. (doi: 10.1016/j.cub.2016.11.004)

van Agtmaal, E. L., André, L. M., Willemse, M., Cumming, S. A., van Kessel, I. D.G., van den Broek, W. J.A.A., Gourdon, G., Furling, D., Mouly, V., Monckton, D. G., Wansink, D. G., Wieringa, B. (2017) CRISPR/Cas9-induced (CTG⋅CAG)n repeat instability in the myotonic dystrophy type 1 locus: implications for therapeutic genome editing. Molecular Therapy, 25, pp. 24-43. (doi: 10.1016/j.ymthe.2016.10.014)

Karnik, R., Waghmare, S., Zhang, B., Larson, E., Lefoulon, C., Gonzalez, W., Blatt, M. R. (2017) Commandeering channel voltage sensors for secretion, cell turgor, and volume control. Trends in Plant Science, 22, pp. 81-95. (doi: 10.1016/j.tplants.2016.10.006)

Asensi-Fabado, M. A., Amtmann, A., Perrella, G. (2017) Plant responses to abiotic stress: the chromatin context of transcriptional regulation. Biochimica et Biophysica Acta: Gene Regulatory Mechanisms, 1860, pp. 106-122. (doi: 10.1016/j.bbagrm.2016.07.015)

Zhang, B., Karnik, R., Waghmare, S., Donald, N. A., Blatt, M. R. (2017) VAMP721 conformations unmask an extended motif for K+ channel binding and gating control. Plant Physiology, 173, pp. 536-551. (doi: 10.1104/pp.16.01549)

Wyse, C. A., Celis Morales, C. A., Graham, N., Fan, Y., Ward, J., Curtis, A. M., Mackay, D., Smith, D. J., Bailey, M. E.S., Biello, S., Gill, J. M.R., Pell, J. P. (2017) Adverse metabolic and mental health outcomes associated with shiftwork in a population-based study of 277,168 workers in UK biobank. Annals of Medicine, 49, pp. 411-420. (doi: 10.1080/07853890.2017.1292045)

Celis-Morales, C., Lyall, D. M., Gray, S., Steell, L., Anderson, J., Iliodromiti, S., Welsh, P., Guo, Y., Petermann, F., Mackay, D. F., Bailey, M. E.S., Pell, J., Gill, J. M.R., Sattar, N. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi: 10.1038/ijo.2017.169)

Ndungu, N. N., Kiatoko, N., Ciosi, M., Salifu, D., Nyansera, D., Masiga, D., Raina, S. K. (2017) Identification of stingless bees (Hymenoptera: Apidae) in Kenya using Morphometrics and DNA barcoding. Journal of Apicultural Research, 56, pp. 341-353. (doi: 10.1080/00218839.2017.1327939)

Olorunniji, F. J., Merrick, C., Rosser, S. J., Smith, M. C.M., Stark, W. M., Colloms, S. D. (2017) Multipart DNA assembly using site-specific recombinases from the large serine integrase family. Springer New York

Olorunniji, F. J., Rosser, S. J., Stark, W. M. (2017) Purification and in vitro characterization of zinc finger recombinases. Humana Press

Antoniou-Kourounioti, R., Howard, M. (2017) Quantitative environmentally triggered switching between stable epigenetic states. Academic Press

2016

Bebel, A., Karaca, E., Kumar, B., Stark, W. M., Barabas, O. (2016) Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending. eLife, 5, (doi: 10.7554/eLife.19706)

Malpas, K. R., Jones, M. A. (2016) Natural variation of circadian rhythms in Kalanchoe species. Haseltonia, 2016, pp. 35-42. (doi: 10.2985/026.022.0107)

Perrella, G., Kaiserli, E. (2016) Light behind the curtain: photoregulation of nuclear architecture and chromatin dynamics in plants. New Phytologist, 212, pp. 908-919. (doi: 10.1111/nph.14269)

Dobson, A. J., Chaston, J. M., Douglas, A. E. (2016) The Drosophila transcriptional network is structured by microbiota. BMC Genomics, 17, (doi: 10.1186/s12864-016-3307-9)

Ross, P. D., Guy, J., Selfridge, J., Kamal, B., Bahey, N., Tanner, E., Gillingwater, T. H., Jones, R. A., Loughrey, C. M., McCarroll, C. S., Bailey, M. E.S., Bird, A., Cobb, S. (2016) Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics, 25, pp. 4389-4404. (doi: 10.1093/hmg/ddw269)

Shone, K., Innes, A., Kilikevicius, A., Statkeviciene, B., Stasiulis, A., Mamkus, G., Malkova, D., Bailey, M. E.S., Venckunas, T., Moran, C. N. (2016) P-87 Acvr1b rs2854464 is Associated with Quantitative Measures of Strength/Power in Lithuanian Athletes and Controls. (doi: 10.1136/bjsports-2016-097120.140)

Vialet-Chabrand, S., Matthews, J. S. A., Brendel, O., Blatt, M.R., Wang, Y., Hills, A., Griffiths, H., Rogers, S., Lawson, T. (2016) Modelling water use efficiency in a dynamic environment: an example using Arabidopsis thaliana. Plant Science, 251, pp. 65-74. (doi: 10.1016/j.plantsci.2016.06.016)

Heilmann, M., Velanis, C. N., Cloix, C., Smith, B. O., Christie, J. M., Jenkins, G. I. (2016) Dimer/monomer status and in vivo function of salt-bridge mutants of the plant UV-B photoreceptor UVR8. Plant Journal, 88, pp. 71-81. (doi: 10.1111/tpj.13260)

Pokhilko, A., Zhao, J., Ebenhöh, O., Smith, M. C.M., Stark, W. M., Colloms, S. D. (2016) The mechanism of φC31 integrase directionality: experimental analysis and computational modelling. Nucleic Acids Research, 44, pp. 7360-7372. (doi: 10.1093/nar/gkw616)

Monckton, D., Ciosi, M., Mubarak, A., Cumming, S., Hamilton, G., Maxwell, A., The International-Venezuela Collaborative Research Group, -, The Scottish Myotonic Dystrophy Genetic Variation Consortium, -, The Track-On HD Research Team, - (2016) Cryptic Polyglutamine Repeat Sequence Variation and Somatic Instability in Huntington’s Disease: Drivers of Pathology? (doi: 10.1136/jnnp-2016-314597.2)

Papanatsiou, M., Amtmann, A., Blatt, M. R. (2016) Stomatal spacing safeguards stomatal dynamics by facilitating guard cell ion transport independent of the epidermal solute reservoir. Plant Physiology, 172, pp. 254-263. (doi: 10.1104/pp.16.00850)

Capewell, P., Cren-Travaille, C., Marchesi, F., Johnston, P., Clucas, C., Benson, R. A., Gorman, T.-A., Calvo-Alvarez, E., Crouzols, A., Jouvion, G., Jamonneau, V., Weir, W., Stevenson, M. L., O'Neill, K., Cooper, A., Swar, N.-r. K., Bucheton, B., Ngoy, D. M., Garside, P., Rotureau, B., MacLeod, A. (2016) The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes. eLife, 5, (doi: 10.7554/eLife.17716)

Armfield, K., Liskamp, R., Wilson, J.B. (2016) Therapeutic Approaches to Targetting Epstein-Barr Virus Related Disease.

Cooper, A., Capewell, P., Clucas, C., Veitch, N., Weir, W., Thomson, R., Raper, J., MacLeod, A. (2016) A primate APOL1 variant that kills Trypanosoma brucei gambiense. PLoS Neglected Tropical Diseases, 10, (doi: 10.1371/journal.pntd.0004903)

Findlay, K. M.W., Jenkins, G. I. (2016) Regulation of UVR8 photoreceptor dimer/monomer photo-equilibrium in Arabidopsis plants grown under photoperiodic conditions. Plant Cell and Environment, 39, pp. 1706-1714. (doi: 10.1111/pce.12724)

Lyall, D. M., Ward, J., Ritchie, S. J., Davies, G., Cullen, B., Celis, C., Bailey, M. E.S., Anderson, J., Evans, J., Mackay, D., McIntosh, A. M., Sattar, N., Smith, D. J., Deary, I. J., Pell, J. P. (2016) Alzheimer disease genetic risk factor APOE e4, and cognitive abilities in 111,739 UK Biobank participants. Age and Ageing, 45, pp. 511-517. (doi: 10.1093/ageing/afw068)

Browitt, A., Finlay, C., Griffiths, M., Rinaldi, C., Ballance, D. (2016) Supporting Student Retention and Success at the University of Glasgow.

Overend, G., Luo, Y., Henderson, L., Douglas, A. E., Davies, S. A., Dow, J. A.T. (2016) Molecular mechanism and functional significance of acid generation in the Drosophila midgut. Scientific Reports, 6, (doi: 10.1038/srep27242)

Johnston, P. R., Dobson, A. J., Rolff, J. (2016) Genomic signatures of experimental adaptation to antimicrobial peptides in Staphylococcus aureus. G3: Genes, Genomes, Genetics, 6, pp. 1535-1539. (doi: 10.1534/g3.115.023622)

Makarova, O., Rodriguez-Rojas, A., Eravci, M., Weise, C., Dobson, A., Johnston, P., Rolff, J. (2016) Antimicrobial defence and persistent infection in insects revisited. Philosophical Transactions of the Royal Society B: Biological Sciences, 371, (doi: 10.1098/rstb.2015.0296)

Isaac, C., Ciosi, M., Hamilton, A., Scullion, K. M., Dede, P., Igbinosa, I. B., Nmorsi, O. P. G., Masiga, D., Turner, C. M. R. (2016) Molecular identification of different trypanosome species and subspecies in tsetse flies of northern Nigeria. Parasites and Vectors, 9, (doi: 10.1186/s13071-016-1585-3)

Perrella, G., Carr, C., Asensi-Fabado, M. A., Donald, N. A., Páldi, K., Hannah, M. A., Amtmann, A. (2016) The Histone Deacetylase Complex (HDC) 1 protein of Arabidopsis thaliana has the capacity to interact with multiple proteins including histone 3-binding proteins and histone 1 variants. Plant Physiology, 171, pp. 62-70. (doi: 10.1104/pp.15.01760)

McVey, M., Finlay, C., Paschke, B., MacIntosh, G. (2016) Development and Student Evaluation of OPENSs – an Online Pre-Entry Nursing Summer School at the University of Glasgow.

Halberg, K. A., Rainey, S. M., Veland, I. R., Neuert, H., Dornan, A. J., Klämbt, C., Davies, S.-A., Dow, J. A.T. (2016) The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules. Nature Communications, 7, (doi: 10.1038/ncomms11266)

Morales, F., Vásquez, M., Santamaría, C., Cuenca, P., Corrales, E., Monckton, D. G. (2016) A polymorphism in the MSH3 mismatch repair gene is associated with the levels of somatic instability of the expanded CTG repeat in the blood DNA of myotonic dystrophy type 1 patients. DNA Repair, 40, pp. 57-66. (doi: 10.1016/j.dnarep.2016.01.001)

Jones, D. D., Beal, J., Haddock-Angelli, T., Gershater, M., de Mora, K., Lizarazo, M., Hollenhorst, J., Rettberg, R., iGEM Interlab Study Contributors, (2016) Reproducibility of fluorescent expression from engineered biological constructs in E. coli. PLoS ONE, 11, (doi: 10.1371/journal.pone.0150182)

Chen, Z.-H., Wang, Y., Wang, J.-W., Babla, M., Zhao, C., Garcia-Mata, C., Sani, E., Differ, C., Mak, M., Hills, A., Amtmann, A., Blatt, M. R. (2016) Nitrate reductase mutation alters potassium nutrition as well as nitric oxide-mediated control of guard cell ion channels in Arabidopsis. New Phytologist, 209, pp. 1456-1469. (doi: 10.1111/nph.13714)

Olorunniji, F. J., Rosser, S. J., Stark, W. M. (2016) Site-specific recombinases: molecular machines for the genetic revolution. Biochemical Journal, 473, pp. 673-684. (doi: 10.1042/bj20151112)

Regan, J. C., Khericha, M., Dobson, A. J., Bolukbasi, E., Rattanavirotkul, N., Partridge, L. (2016) Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction. eLife, 5, (doi: 10.7554/eLife.10956)

Blatt, M. R. (2016) Plant physiology: redefining the enigma of metabolism in stomatal movement. Current Biology, 26, pp. R107-R109. (doi: 10.1016/j.cub.2015.12.025)

Barrett, M., Sloan, W., Stark, W., Watson, I. (2016) New Developments in Synthetic Biology at the University of Glasgow.

Chaston, J. M., Dobson, A. J., Newell, P. D., Douglas, A. E. (2016) Host genetic control of the microbiota mediates the Drosophila nutritional phenotype. Applied and Environmental Microbiology, 82, pp. 671-679. (doi: 10.1128/AEM.03301-15)

Pokhilko, A., Zhao, J., Stark, W. M., Colloms, S. D., Ebenhöh, O. (2016) A simplified mathematical model of directional DNA site-specific recombination by serine integrases. Journal of the Royal Society: Interface, 14, (doi: 10.1098/rsif.2016.0618)

Minguet-Parramona, C., Wang, Y., Hills, A., Vialet-Chabrand, S., Griffiths, H., Rogers, S., Lawson, T., Lew, V. L., Blatt, M. R. (2016) An optimal frequency in Ca2+ oscillations for stomatal closure is an emergent property of ion transport in guard cells. Plant Physiology, 170, pp. 33-42. (doi: 10.1104/pp.15.01607)

Hector, R. D., Dando, O., Landsberger, N., Kilstrup-Nielsen, C., Kind, P. C., Bailey, M. E.S., Cobb, S. R. (2016) Characterisation of CDKL5 transcript isoforms in human and mouse. PLoS ONE, 11, (doi: 10.1371/journal.pone.0157758)

Smith, D.J. et al. (2016) Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. Molecular Psychiatry, 21, pp. 749-757. (doi: 10.1038/mp.2016.49)

Litthauer, S., Battle, M. W., Jones, M. A. (2016) Phototropins do not alter accumulation of evening-phased circadian transcripts under blue light. Plant Signaling and Behavior, 11, (doi: 10.1080/15592324.2015.1126029)

Weir, W., Capewell, P., Foth, B., Clucas, C., Pountain, A., Steketee, P., Veitch, N., Koffi, M., De Meeûs, T., Kaboré, J., Camara, M., Cooper, A., Tait, A., Jamonneau, V., Bucheton, B., Berriman, M., MacLeod, A. (2016) Population genomics reveals the origin and asexual evolution of human infective trypanosomes. eLife, 5, (doi: 10.7554/eLife.11473)

Merrick, C.A., Wardrope, C., Paget, J.E., Colloms, S.D., Rosser, S.J. (2016) Rapid optimization of engineered metabolic pathways with serine integrase recombinational assembly (SIRA) Elsevier

Velanis, C. N., Herzyk, P., Jenkins, G. I. (2016) Regulation of transcription by the Arabidopsis UVR8 photoreceptor involves a specific histone modification. Plant Molecular Biology, 92, pp. 425-443. (doi: 10.1007/s11103-016-0522-3)

Landry, G. M., Hirata, T., Anderson, J. B., Cabrero, P., Gallo, C. J.R., Dow, J. A.T., Romero, M. F. (2016) Sulfate and thiosulfate inhibit oxalate transport via a dPrestin(mSlc26a6)-dependent mechanism in an insect model of calcium oxalate nephrolithiasis. American Journal of Physiology: Renal Physiology, 310, pp. F152-F159. (doi: 10.1152/ajprenal.00406.2015)

Cannell, E., Dornan, A. J., Halberg, K. A., Terhzaza, S., Dow, J. A.T., Davies, S. A. (2016) The corticotropin-releasing factor-like diuretic hormone 44 (DH44) and kinin neuropeptides modulate desiccation and starvation tolerance in Drosophila melanogaster. Peptides, 80, (doi: 10.1016/j.peptides.2016.02.004)

2015

Overend, G., Cabrero, P., Halberg, K. A.,, Ranford-Cartwright, L. C., Woods, D., Davies, S. A., Dow, J. A.T. (2015) A comprehensive transcriptomic view of renal function in the malaria vector, Anopheles gambiae. Insect Biochemistry and Molecular Biology, 67, pp. 47-58. (doi: 10.1016/j.ibmb.2015.05.007)

Terhzaz, S., Cabrero, P., Brinzer, R. A., Halberg, K. A., Dow, J. A.T., Davies, S.-A. (2015) A novel role of Drosophila cytochrome P450-4e3 in permethrin insecticide tolerance. Insect Biochemistry and Molecular Biology, 67, pp. 38-46. (doi: 10.1016/j.ibmb.2015.06.002)

Brinzer, R., Henderson, L., Marchiondo, A. A., Woods, D. J., Davies, S., Dow, J. A. T. (2015) Metabolomic profiling of permethrin-treated Drosophila melanogaster identifies a role for tryptophan catabolism in insecticide survival. Insect Biochemistry and Molecular Biology, 67, pp. 74-86. (doi: 10.1016/j.ibmb.2015.09.009)

Dow, J. A. T., Davies, S. A. (2015) What is an epitheliome, anyway? Insect Biochemistry and Molecular Biology, 67, pp. 1. (doi: 10.1016/j.ibmb.2015.10.013)

Kaiserli, E., Páldi, K., O’Donnell, L., Batalov, O., Pedmale, U. V., Nusinow, D. A., Kay, S. A., Chory, J. (2015) Integration of light and photoperiodic signaling in transcriptional nuclear foci. Developmental Cell, 35, pp. 311-321. (doi: 10.1016/j.devcel.2015.10.008)

Alles, J., Hasler, D., Kazmi, S. M. A., Tesson, M., Hamilton, A., Schlegel, L., Marx, S., Eichner, N., Reinhardt, R., Meister, G., Wilson, J. B., Grässer, F. A. (2015) Epstein-Barr virus EBER transcripts affect miRNA-mediated regulation of specific targets and are processed to small RNA species. Non-Coding RNA, 1, pp. 170-191. (doi: 10.3390/ncrna1030170)

Jones, M. A., Hu, W., Litthauer, S., Lagarias, J. C., Harmer, S. L. (2015) A constitutively active allele of phytochrome B maintains circadian robustness in the absence of light. Plant Physiology, 169, pp. 814-825. (doi: 10.1104/pp.15.00782)

Litthauer, S., Battle, M. W., Lawson, T., Jones, M. A. (2015) Phototropins maintain robust circadian oscillation of PSII operating efficiency under blue light. Plant Journal, 83, pp. 1034-1045. (doi: 10.1111/tpj.12947)

Chintapalli, V. R., Kato, A., Henderson, L., Hirata, T., Woods, D. J., Overend, G., Davies, S. A., Romero, M. F., Dow, J. A. T. (2015) Transport proteins NHA1 and NHA2 are essential for survival, but have distinct transport modalities. Proceedings of the National Academy of Sciences of the United States of America, 112, pp. 11720-11725. (doi: 10.1073/pnas.1508031112)

Bowyer, J., Zhao, J., Rosser, S., Colloms, S., Bates, D. (2015) Development and experimental validation of a mechanistic model of in vitro DNA recombination. (doi: 10.1109/EMBC.2015.7318519)

Grefen, C., Karnik, R., Larson, E., Lefoulon, C., Wang, Y., Waghmare, S., Zhang, B., Hills, A., Blatt, M. R. (2015) A vesicle-trafficking protein commandeers Kv channel voltage sensors for voltage-dependent secretion. Nature Plants, 1, (doi: 10.1038/nplants.2015.108)

Amtmann, A., Ma, H., Wagner, D. (2015) Chromatin and epigenetics. Plant Physiology, 168, pp. 1185-1188. (doi: 10.1104/pp.15.01023)

Dutta, D., Dobson, A. J., Houtz, P. L., Gläßer, C., Revah, J., Korzelius, J., Patel, P. H., Edgar, B. A., Buchon, N. (2015) Regional cell-specific transcriptome mapping reveals regulatory complexity in the adult Drosophila midgut. Cell Reports, 12, pp. 346-358. (doi: 10.1016/j.celrep.2015.06.009)

Qi, Q. et al. (2015) Dietary intake, FTOGenetic variants, and adiposity: a combined analysis of over 16,000 children and adolescents. Diabetes, 64, pp. 2467-2476. (doi: 10.2337/db14-1629)

Gao, X., Wilson, J.B. (2015) LMP1: Chronic Inflammation and Carcinogenesis.

de la Fila, A. G., Bain, S. A., Ross, L. (2015) Haplodiploidy and the reproductive ecology of arthropods. Current Opinion in Insect Science, 9, pp. 36-43. (doi: 10.1016/j.cois.2015.04.018)

Zhang, B., Karnik, R., Wang, Y., Wallmeroth, N., Blatt, M. R., Grefen, C. (2015) The arabidopsis R-SNARE VAMP721 interacts with KAT1 and KC1 K+ channels to moderate K+ current at the plasma membrane. Plant Cell, 27, pp. 1697-1717. (doi: 10.1105/tpc.15.00305)

van Engelen, B., The OPTIMISTIC Consortium, (2015) Cognitive behaviour therapy plus aerobic exercise training to increase activity in patients with myotonic dystrophy type 1 (DM1) compared to usual care (OPTIMISTIC): study protocol for randomised controlled trial. Trials, 16, (doi: 10.1186/s13063-015-0737-7)

Bühlmann, M., Walrad, P., Rico, E., Ivens, A., Capewell, P., Naguleswaran, A., Roditi, I., Matthews, K. R. (2015) NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway. Nucleic Acids Research, 43, pp. 4491-4504. (doi: 10.1093/nar/gkv330)

Dobson, A. J., Chaston, J. M., Newell, P. D., Donahue, L., Hermann, S. L., Sannino, D. R., Westmiller, S., Wong, A. C.-N., Clark, A. G., Lazzaro, B. P., Douglas, A. E. (2015) Corrigendum: Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster. Nature Communications, 6, (doi: 10.1038/ncomms8296)

Papanatsiou, M., Scuffi, D., Blatt, M. R., Garia-Mata, C. (2015) Hydrogen sulphide regulates inward-rectifying K+ channels in conjunction with stomatal closure. Plant Physiology, 168, pp. 29-35. (doi: 10.1104/pp.114.256057)

Morales, F., Vásquez, M., Cuenca, P., Campos, D., Santamaría, C., del Valle, G., Brian, R., Sittenfeld, M., Monckton, D. G. (2015) Parental age effects, but no evidence for an intrauterine effect in the transmission of myotonic dystrophy type 1. European Journal of Human Genetics, 23, pp. 646-653. (doi: 10.1038/ejhg.2014.138)

Finlay, C., McVey, M., Paschke, B. (2015) A Pre-Entry Distance Course on Moodle: Articulating Course Expectations, Aiming to Impact on Access and Student Confidence.

DeLeeuw, J., Weir, J., Copsey, D., Roden, C., Deeley, S., Huston, E., McVey, M., Finlay, C. (2015) Developing Graduate Attributes and Improving Student Employability Through Work-based Learning: Opportunities, Successes and Challenges.

Larson, E., Fyfe, I., Morton, A. J., Monckton, D. G. (2015) Age-, tissue- and length-dependent bidirectional somatic CAG•CTG repeat instability in an allelic series of R6/2 Huntington disease mice. Neurobiology of Disease, 76, pp. 98-111. (doi: 10.1016/j.nbd.2015.01.004)

Sykes, A., Morrison, D., Gray, J. (2015) Half as Much but Twice as Good: LEAF and New Directions in Assessment and Feedback.

Halberg, K., Terhzaz, S., Cabrero, P., Davies, S. A., Dow, J. A.T. (2015) Tracing the evolutionary origins of insect renal function. Nature Communications, 6, (doi: 10.1038/ncomms7800)

Terhzaz, S., Teets, N., Cabrero, P., Henderson, L., Richie, M. G., Nachman, R. J., Dow, J. A. T., Denlinger, D. L., Davies, S.-A. (2015) The insect capa neuropeptides impact desiccation and cold tolerance. Proceedings of the National Academy of Sciences of the United States of America, 112, pp. 2882-2887. (doi: 10.1073/pnas.1501518112)

Kaiserli, E., Chory, J. (2015) The role of phytochromes in triggering plant developmental transitions. John Wiley and Sons Ltd

Karnik, R., Zhang, B., Waghmare, S., Aderhold, C., Grefen, C., Blatt, M. R. (2015) Binding of SEC11 indicates its role in SNARE recycling after vesicle fusion and identifies two pathways for vesicular traffic to the plasma membrane. Plant Cell, 27, pp. 675-694. (doi: 10.1105/tpc.114.134429)

Dobson, A. J., Chaston, J. M., Newell, P. D., Donahue, L., Hermann, S. L., Sannino, D. R., Westmiller, S., Wong, A. C.-N., Clark, A. G., Lazzaro, B. P., Douglas, A. E. (2015) Host genetic determinants of microbiota-dependent nutrition revealed by genome-wide analysis of Drosophila melanogaster. Nature Communications, 6, (doi: 10.1038/ncomms7312)

Finlay, C. (2015) Does Size Matter? Biological Sciences Review, 27, pp. 2-6.

Capewell, P., Cooper, A., Clucas, C., Weir, W., MacLeod, A. (2015) A co-evolutionary arms race: trypanosomes shaping the human genome, humans shaping the trypanosome genome. Parasitology, 142, pp. S108-S119. (doi: 10.1017/S0031182014000602)

Heilmann, M., Christie, J. M., Kennis, J. T.M., Jenkins, G. I., Mathes, T. (2015) Photoinduced transformation of UVR8 monitored by vibrational and fluorescence spectroscopy. Photochemical and Photobiological Sciences, 14, pp. 252-257. (doi: 10.1039/c4pp00246f)

McVey, M., Finlay, C. (2015) Assessment Designed Around Graduate Attributes: Making Best Use of Available Technology to Foster Student Interaction and Support the Individual.

Minas, K., Karunakaran, E., Bond, T., Gandy, C., Honsbein, A., Madsen, M., Amezaga, J., Amtmann, A., Templeton, M.R., Biggs, C.A., Lawton, L. (2015) Biodesalination: an emerging technology for targeted removal of Na+and Cl−from seawater by cyanobacteria. Desalination and Water Treatment, 55, pp. 2647-2668. (doi: 10.1080/19443994.2014.940647)

Capewell, P., Cooper, A., Clucas, C., Weir, W., Vaikkinen, H., Morrison, L., Tait, A., MacLeod, A. (2015) Exploiting genetic variation to discover genes involved in important disease phenotypes. Methods in Molecular Biology, 1201, pp. 91-107. (doi: 10.1007/978-1-4939-1438-8_5)

Gadalla, K. K. E., Ross, P. D., Hector, R. D., Bahey, N. G., Bailey, M. E.S., Cobb, S. R. (2015) Gene therapy for Rett syndrome: prospects and challenges. Future Neurology, 10, pp. 467-484. (doi: 10.2217/fnl.15.29)

Olorunniji, F. J., McPherson, A. L., Pavlou, H. J., McIlwraith, M. J., Brazier, J. A., Cosstick, R., Stark, W. M. (2015) Nicked-site substrates for a serine recombinase reveal enzyme–DNA communications and an essential tethering role of covalent enzyme–DNA linkages. Nucleic Acids Research, (doi: 10.1093/nar/gkv521)

Wardle, S. L., Bailey, M. E., Kilikevicius, A., Malkova, D., Wilson, R. H., Venckunas, T., Moran, C. (2015) Plasma microRNA levels differ between endurance and strength athletes. PLoS ONE, 10, (doi: 10.1371/journal.pone.0122107)

Mathes, T., Heilmann, M., Pandit, A., Zhu, J., Ravensbergen, J., Kloz, M., Fu, Y., Smith, B.O., Christie, J.M., Jenkins, G.I., Kennis, J.T.M. (2015) Proton-coupled electron transfer constitutes the photoactivation mechanism of the plant photoreceptor UVR8. Journal of the American Chemical Society, 137, pp. 8113-8120. (doi: 10.1021/jacs.5b01177)

Ulm, R., Jenkins, G. (2015) Q&A: How do plants sense and respond to UV-B radiation? BMC Biology, 13, (doi: 10.1186/s12915-015-0156-y)

Suárez, M. B., Alonso-Nuñez, M. L., del Rey, F., McInerny, C. J., Vázquez de Aldana, C. R. (2015) Regulation of Ace2-dependent genes requires components of the PBF complex in schizosaccharomyces pombe. Cell Cycle, 14, pp. 3124-3137. (doi: 10.1080/15384101.2015.1078035)

Ji, H., Wang, Y., Cloix, C., Li, K., Jenkins, G. I., Wang, S., Shang, Z., Shi, Y., Yang, S., Li, X. (2015) The arabidopsis RCC1 family protein TCF1 regulates freezing tolerance and cold acclimation through modulating lignin biosynthesis. PLoS Genetics, 11, (doi: 10.1371/journal.pgen.1005471)

Stark, W. M. (2015) The serine recombinases. ASM Press

Postgraduate research students

Refine By

Molecular genetics research within the School of Molecular Biosciences ranges from:

  • the analysis of DNA sequence and epigenetic variation in health and disease, through structural analysis of DNA -protein interactions to genomic approaches
  • to the analysis of gene function within cells, organisms and populations & the development of genetics-informed therapeutic approaches.

An additional focus is on gene-environment interactions, including nutrition and the microbiome in animals, and temperature, light and salinity in plants. Research advances are impacting in a number of areas, most notably to problems in healthy ageing, food security and synthetic biology.

Topics covered within the theme include:

  • site specific recombination and transposition
  • inherited human disease and variation
  • animal models of human disease and development of molecular therapies
  • insect integrative physiology and ageing
  • epigenetic and nuclear organisational responses to environmental stimuli in plants

Research within the Molecular Genetics theme complements genetic research ongoing elsewhere across the College. We also maintain strong links with the West of Scotland Genetic Services at the Queen Elizabeth University Hospital Glasgow. Our work is very well supported by next-generation DNA sequencing, single-cell and spatial transcriptomics, and other multi-omic systems approaches accessed through Glasgow Polyomics. Molecular Genetics staff also make major research-led teaching contributions to our highly rated BSc Honours degree in Genetics and a variety of masters programmes.