Paediatric Gastroenterology, Hepatology and Nutrition Research Group

Paediatric Gastroenterology, Hepatology and Nutrition Research Group

The Department of Paediatric Gastroenterology, Hepatology and Nutrition, based in the Royal Hospital for Children Glasgow, cares for roughly half of the paediatric population of Scotland.  Major clinical and research interests of the Department include inflammatory bowel disease, gastrointestinal microbiota, complex enteral and parenteral nutrition and the development of novel therapies for gastrointestinal disease.   Members of the team collaborate extensively with colleagues throughout Scotland, the United Kingdom and the rest of the world.   We have clinical research experience in industry-sponsored trials, collaborative multicentre studies and we also continue to develop our own investigator-led  research programme.   The department actively supports and encourages clinical training in all aspects of paediatric gastroenterology, hepatology and nutrition including paediatric endoscopy, and offers research training with degree programmes to all levels including PhD.

 

 

Research Contacts

Research Contacts

Dr Richard Hansen

Dr Richard Hansen's main research interest is the gastrointestinal mucosal microbiota and its importance in paediatric disease, particularly inflammatory bowel disease.  He is particularly interested in the molecular characterisation of the microbiota and its subsequent modification for the purposes of therapeutic effect.  This theme of microbial therapeutics fits nicely into the concept of stratified medicine, since the microbiota is highly individualistic yet also modifiable.  Being a paediatrician, Dr Hansen is naturally interested in how the gut microbiota develops as the child grows and matures, particularly at the earliest stages of microbial colonisation.   This area of research is a natural extension of Dr Hansen's CSO-funded PhD studies during which he was the first to catalogue and publish the colonic microbiota in paediatric IBD at the onset of disease.

Grants

  • The paediatric gastrointestinal microbiota as a stratified medicine target for novel diagnostics and microbial intervention.   Hansen R (personal fellowship) 1/4/15 - 31/3/18.  £61,954, NHS Research Scotland.
  • STOP-COLITIS (faecal transplant in ulcerative colitis).   As a member of a UK-wide steering group 20/3/15 - 20/3/18.  £2,633,985, Joint MRC/NIHR Efficacy and Mechanisms Evaluation Committee
  • Novel management of Crohn's disease by dietary manipulation of the gut microbiome.  Gerasimidis K, Hansen R (PhD supervisors) 1/10/14 - 30/9/17.  £59,999, Glasgow Children's Hospital Charity
  • The colonic microbiota of de-novo paediatric Crohn's disease.  Hansen R, Hold GL, Russel RK, El-Omar EM. 1/4/11 - 31/3/12.  £11,120, NHS Grampian Endowments.
  • Is meconium sterile at birth?  A molecular assessment of an infant's first stool for the presence and composition of bacterial populations.  Hansen R, Scott KP, Hold Gl.   1/11/10 - 31/10/11. £10,719, NHS Grampian, Neonatal Endowments.
  • The role of non-pylori Helicobacter in paediatric inflammatory bowel disease.  Hansen R (persona PhD fellowship); Supervisors : Hold GL, El-Omar EM.  1/3/09 - 29/2/12.  £182,235, Scottish Executive Health Department - Chief Scientist Office.

Dr Richard Russell

Dr Richard Russell is an Honorary Clinical Associate Professor and Consultant Paediatric Gastroenterologist based at the Royal Hospital for Children, Glasgow.   His main research interest focuses on the gastrointestinal mucosal microbiota and its importance in paediatric disease, particularly inflammatory bowel disease.   Dr Russell is actively involved in research supervision, currently co-supervising three PhD students and an MD student.


Dr Diana Flynn


Dr Andrew Barclay


Dr Rachel Taylor