Dr Konstantinos Gerasimidis

Senior Lecturer (Medicine)
Associate Academic (Institute of Health & Wellbeing)

telephone: 01412018689
email: Konstantinos.Gerasimidis@glasgow.ac.uk

ORCID iD https://orcid.org/0000-0001-9432-2200

Biography

Dr Konstantinos Gerasimidis is Senior Lecturer in Clinical Nutrition. He has graduated in Nutrition and Dietetics and completed his postgraduate studies in Clinical Nutrition. During his doctoral research at the University of Glasgow, he explored the effect of exclusive enteral nutrition on the gut microbiota and nutritional status of children with Crohn’s disease. He holds an honorary contract as Clinical Paediatric Nutrition Scientist with the National Health Service at Greater Glasgow and Clyde.

Affiliations and memberships

He is the Allied Health Professional representative in the Nutrition Committee of the European Society of Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN).
He is faculty member of the Dietetic Working Group of European Crohn’s and Colitis Organisation (D-ECCO)
He is the Secretary elect of the Special Interest Group in Clinical Paediatric Nutrition Group of the European Society of Clinical Nutrition and Metabolism (ESPEN).
He is State Registered Dietitian in Greece

Research interests

Dr Gerasimidis main research focuses on two areas:

Disease-associated malnutrition

Dr Gerasimidis’ clinical research investigates the link between malnutrition and clinical outcomes in adults and children with acute and chronic disease. He is particularly interested in the screening and assessment of disease-associated malnutrition and its impact on patients’ clinical outcomes. He has been instrumental in the development of the Paediatric Yorkhill Malnutrition Score (PYMS) which is endorsed for clinical use by NHS Scotland, http://www.knowledge.scot.nhs.uk/home.aspx,

Dr Gerasimidis was the local principal investigator of the European malnutrition screening study sponsored by the European Society of Clinical Nutrition and Metabolism (ESPEN). His current research explores how nutritional interventions can improve clinical outcomes in disease-associated malnutrition. Ongoing research projects include:

1) Micronutrient deficiencies and post-operative outcomes in children with congenital heart defects

2) Nutritional issues and management in children with phenylketonuria

3) The Children European Estimator of Weight (CEEW) a weight prediction equations for use in paediatric accident and emergency settings and critical care.

4) The development and validation of the infant early nutrition warning score

5) Dietary intake and eating habits in elderly hospitalised patients.

Diet and gut microbiota interaction in health and disease

Dr Gerasimidis also leads a laboratory team which explores the role of gut microbiota and its interaction with diet in the onset, propagation and management of acute and chronic conditions. He has a strong interest in exploring the effect of habitual diet, elimination diets and artificial nutritional support on the gut microbiota of children and adults with inflammatory bowel disease. With clinical colleagues from the National Health Service, they have developed a novel diet (Crohn’s Disease Treatment by Eating or CD-TREAT) to treat Crohn’s disease through manipulation of the gut microbiota. He also explores the role of gut microbiota in other non-communicable conditions such as obesity, juvenile arthritis and intestinal failure. He is the local academic principal investigator of the STOP-colitis study; a UK multicentre intervention study aiming to treat ulcerative colitis using faecal material transplantations.

His laboratory team holds in-house expertise in characterising the microbiota composition and functionality using molecular microbiology and chromatographic techniques. His current research encompasses clinical trials, in-vitro experiments and animal models, in collaborations with clinical colleagues from the National Health Service and other internal and external academic establishments. He is the co-ordinator of a cross-disciplinary research group with a special interest in Bacteria, Immunology, Nutrition, Gastroenterology and Omics (BINGO) group. Ongoing research projects encompass:

1) The role of gut microbiota in children with coeliac disease

2) Gut microbiota in obesity. Cause or effect?

3) The effect of structured exercise sessions on the gut microbiota of women in increased cardiovascular risk

4) Fibre and fermentation capacity of people with inflammatory bowel disease

Research funding

His work is funded by various charities (e.g. Glasgow Children’s Hospital Charity, Catherine McEwan Foundation, Crohn’s in Childhood Research Association, Crohn’s and Colitis UK, Europe, research councils in UK (e.g. Medical Research Council), the National Institute of Health Research in the UK, industry (e.g. Nestle, Nutricia, Mead Johnson Nutrition) and health professional bodies (e.g. British Society of Paediatric Gastroenterology, Hepatology and Nutrition, the European Crohn’s and Colitis Organisation) and the Scottish Enterprise.

Current research team

His current research team consists of four postdoctoral research associates, two research technicians and a team of 10 PhD students.

Visit his Google Scholar page

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

The Role of Dietary D-serine in Health and Disease
Biotechnology and Biological Sciences Research Council
2018 - 2021
The Imagekids study
Glasgow Children`s Hospital Charity
2018 - 2018
Can gut microbiota predict tolerance to enteral nutrition in children with intestinal failure? A proof-of-concept study
Erasmus MC Holding
2017 - 2018
FPIES Microbiome
FPIES Foundation
2017 - 2018
Exploring the inter-kingdom relationships of gut microbiota in Crohn's disease
British Society Paediatric Gastroenterology Hepatology & Nutrit
2017 - 2018
Investigation of the incidence, demographics and nutritional profile of childhood vitamin D deficiency in Greater Glasgow and Clyde
Glasgow Children`s Hospital Charity
2017 - 2019
Dietary treatment of patients with inflammatory bowel disease
Cure Crohn's Colitis
2017 - 2018
Precision targeting of the gut microbiome for the treatment of Inflammatory Bowel Disease and Autoimmune diseases
Scottish Enterprise
2017 - 2019
Intestinal Mycobiome: Unravelling the role of fungal microbiota in paediatric Crohn's disease
European Crohn`s and Colitis Organisation
2017 - 2017
A pilot open label study to explore the efficacy of CD-treat in people with Crohns disease
Royal Hospital for Sick Children
2016 - 2017
Precision targeting of the microbiome for the treatment of Crohn's disease
Scottish Enterprise
2016 - 2016
CiC Precision engineering of the human gut microbiome
Medical Research Council
2016 - 2018
Nutritional aspects in people with phenylketonuria
NHS Greater Glasgow and Clyde
2015 - 2016
Nutritional aspects in people with phenylketonuria
NHS Greater Glasgow and Clyde Endowment Funds
2015 - 2016
Double blinded randomised controlled trial to investigate efficacy of faecal microbiota transplantation in achieving & maintaining remission for patients with ulcerative colitis 13/179 (STOp-Colitis)
National Institute for Health Research
2015 - 2020
Micronutrient deficiencies and clinical outcome in children and infants with congenital heart diseases (CHD) admitted for corrective surgery. A proof-of-concept study.
Glasgow Children`s Hospital Charity
2015 - 2016
The Catherine McEwan Foundation Fellowship
Royal Hospital for Sick Children
2015 - 2017
Characterisation of Gut Microbial Taxonomy and Functionality using Next Generation Sequencing in Children with Crohn's Disease during Exclusive Enteral Nutrition.
Crohn`s in Childhood Research Association
2013 - 2013
Gut microbiota and energy from colonic fermentation of carbohydrate in children with simple and pathological obesity; cause or effect.
Glasgow Children`s Hospital Charity
2011 - 2013
Nutritional Status and Microbiota in Coeliac Disease
Nutricia Research Foundation
2011 - 2013
A pilot study to investigate the microbiota profile and metabolic activity in the colon of juvenile idiopathic arthritis patients at risk of developing Crohn's disease
Glasgow Children`s Hospital Charity
2011 - 2012
'Nutritional Care of People Affected by Cancer' Education Programme Evaluation
Macmillan Cancer Support
2010 - 2011
ESPEN Nutritional Screening Study
Ludwig Maximilian University of Munich
2010 - 2010
Characterisation of gut bacterial diversity in paediatric patients with Crohn's disease. Changes during treatment with nutritional therapy and comparison with healthy children and healthy relatives.
Glasgow Children`s Hospital Charity
2010 - 2012

Teaching

Dr Gerasimidis leads the Clinical Nutrition Specialisation module of the MSc in Human Nutrition.

Publications

List by: Type | Date

Jump to: 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2008 | 2007

Number of items: 65.

2018

Lomer, M. C.E., Cahill, O., Baschali, A., Partha Sarathy, P., Sarantidou, M., Mantzaris, G. J., Gaya, D., Katsanos, K., Christodoulou, D. and Gerasimidis, K. (2018) A multicentre study of nutrition risk assessment in adult patients with inflammatory 1 bowel disease attending outpatient clinics. Annals of Nutrition and Metabolism, (Accepted for Publication)

Gerasimidis, K. , Zafeiropoulou, K., Mackinder-Jonas, M., Ijaz, U. Z., Duncan, H., Buchanan, E., Cardigan, T., Edwards, C. A. , McGrogan, P. and Russell, R. K. (2018) Comparison of clinical methods with the faecal gluten immunogenic peptide to assess gluten intake in coeliac disease. Journal of Pediatric Gastroenterology and Nutrition, 67(3), pp. 356-360. (doi:10.1097/MPG.0000000000002062) (PMID:29916953)

Gerasimidis, K. et al. (2018) A multicentre development and evaluation of a dietetic referral score for nutritional risk in sick infants. Clinical Nutrition, (Accepted for Publication)

Eveleens, R.D., Gerasimidis, K. , Chourdakis, M., Huysentruyt, K., Koletzko, B., Hulst, J.M. and Joosten, K.F.M. (2018) Current clinical trials in paediatrics: report of the ESPEN Special Interest Group in Paediatrics. Clinical Nutrition ESPEN, (Accepted for Publication)

Neelis, E., de Koning, B., Rings, E., Wijnen, R., Nichols, B., Hulst, J. and Gerasimidis, K. (2018) The gut microbiome in patients with intestinal failure: Current evidence and implications for clinical practice. Journal of Parenteral and Enteral Nutrition, (Accepted for Publication)

Duncan, H., Painesi, A., Buchanan, E., McGrogan, P., Gerasimidis, K. , Walker, G., Haddock, G. and Russell, R.K. (2018) Percutaneous endoscopic gastrostomy placement in paediatric Crohn's disease patients contributes to both improved nutrition and growth. Acta Paediatrica, 107(6), pp. 1094-1099. (doi:10.1111/apa.14268) (PMID:29423918)

Fatima, S., Malkova, D. , Wright, C. and Gerasimidis, K. (2018) Impact of therapeutic food compared to oral nutritional supplements on nutritional outcomes in mildly underweight healthy children in a low-medium income society. Clinical Nutrition, 37(3), pp. 858-863. (doi:10.1016/j.clnu.2017.03.006) (PMID:28343801)

Koci, O., Logan, M., Svolos, V., Russell, R. K., Gerasimidis, K. and Ijaz, U. Z. (2018) An automated identification and analysis of ontological terms in gastrointestinal diseases and nutrition-related literature provides useful insights. PeerJ, (Accepted for Publication)

Barroso, T., Conway, F., Emel, S., McMillan, D. , Young, D., Karteszi, H., Gaya, D. R. and Gerasimidis, K. (2018) Patients with inflammatory bowel disease have higher abdominal adiposity and less skeletal mass than healthy controls. Annals of Gastroenterology, (Accepted for Publication)

Huysentruyt, K., Hulst, J., Bian, F., Shamir, R., White, M., Galera-Martinez, R., Morais-Lopez, A., Kansu, A. and Gerasimidis, K. (2018) Opinions and practices of healthcare professionals on assessment of disease associated malnutrition in children: results from an international survey. Clinical Nutrition, (doi:10.1016/j.clnu.2018.03.015) (PMID:29653864) (In Press)

Mason, A., Gerasimidis, K. , Iljuhhina, J., Laird, S., Munro, J., Gaya, D. R., Russell, R. K. and Ahmed, S. F. (2018) Long-term skeletal disproportion in childhood-onset Crohn’s disease. Hormone Research in Paediatrics, 89(2), pp. 132-135. (doi:10.1159/000485185)

Khan, M. J., Gerasimidis, K. , Edwards, C. A. and Shaikh, M. G. (2018) Mechanisms of obesity in Prader-Willi syndrome. Pediatric Obesity, 13(1), pp. 3-13. (doi:10.1111/ijpo.12177) (PMID:27863129)

Alfheeaid, H. , Gerasimidis, K. , Năstase, A.-M., Elhauge, M., Cochrane, B. and Malkova, D. (2018) Impact of phenylketonuria type meal on appetite, thermic effect of feeding and postprandial fat oxidation. Clinical Nutrition, (doi:10.1016/j.clnu.2017.03.005) (PMID:28318688) (In Press)

2017

Logan, M., Ijaz, U.Z., Hansen, R., Gerasimidis, K. and Russell, R.K. (2017) Letter: reproducible evidence shows that exclusive enteral nutrition significantly reduces faecal calprotectin concentrations in children with active Crohn's Disease. Alimentary Pharmacology and Therapeutics, 46(11-12), pp. 1119-1120. (doi:10.1111/apt.14351) (PMID:29105140)

Sigall-Boneh, R. et al. (2017) Research gaps in diet and nutrition in inflammatory bowel disease. A topical review by D-ECCO Working Group (Dietitians of ECCO). Journal of Crohn's and Colitis, 11(12), pp. 1407-1419. (doi:10.1093/ecco-jcc/jjx109) (PMID:28961811)

Mcvey, L., Young, D., Hulst, J., Bradley, S., Raudaschl, A., Karagiozoglou, T., Macleod, I., Joosten, K., Spenceley, N. and Gerasimidis, K. (2017) Development and validation of a novel paediatric weight estimation equation in multinational cohorts of sick children. Resuscitation, 117, pp. 118-121. (doi:10.1016/j.resuscitation.2017.04.025) (PMID:28465140)

van der Hooft, J. J.J. , Wandy, J., Young, F., Padmanabhan, S. , Gerasimidis, K. , Burgess, K. E.V., Barrett, M. P. and Rogers, S. (2017) Unsupervised discovery and comparison of structural families across multiple samples in untargeted metabolomics. Analytical Chemistry, 89(14), pp. 7569-7577. (doi:10.1021/acs.analchem.7b01391) (PMID:28621528) (PMCID:PMC5524435)

Gerasimidis, K. , Hulst, J.M., Chourdakis, M., Huysentruyt, K., Koletzko, B. and Joosten, K.F.M. (2017) The launch of the ESPEN Special Interest Group in Paediatric Clinical Nutrition. Clinical Nutrition ESPEN, 19, pp. 45-48. (doi:10.1016/j.clnesp.2017.01.012)

Ijaz, U. Z. et al. (2017) The distinct features of microbial 'dysbiosis' of Crohn's disease do not occur to the same extent in their unaffected, genetically linked kindred. PLoS ONE, 12(2), e0172605. (doi:10.1371/journal.pone.0172605) (PMID:28222161) (PMCID:PMC5319678)

Svolos, V. et al. (2017) Dietary Manipulation of the Healthy Human and Colitic Murine Gut Microbiome by CD-TREAT Diet and Exclusive Enteral Nutrition; A Proof of Concept Studyy. 12th Congress of ECCO, Barcelona, Spain, 15-18 Feb 2017. S29-S30. (doi:10.1093/ecco-jcc/jjx002.045)

Armstrong, J., Buchanan, E., Duncan, H., Ross, K. and Gerasimidis, K. (2017) Dietitians’ perceptions and experience of blenderised feeds for paediatric tube-feeding. Archives of Disease in Childhood, 102(2), pp. 152-156. (doi:10.1136/archdischild-2016-310971) (PMID:27677635)

Svolos, V. et al. (2017) Dietary treatment of Crohn’s disease: perceptions of families with children treated by exclusive enteral nutrition, a questionnaire survey. BMC Gastroenterology, 17, 14. (doi:10.1186/s12876-016-0564-7) (PMID:28103809) (PMCID:PMC5247812)

2016

Biskou, O., Gardner-Medwin, J., Mackinder, M., Bertz, M., Clark, C., Svolos, V., Russell, R. K., Edwards, C. A. , McGrogan, P. and Gerasimidis, K. (2016) Faecal calprotectin in treated and untreated children with coeliac disease and juvenile idiopathic arthritis. Journal of Pediatric Gastroenterology and Nutrition, 63(5), e112-e115. (doi:10.1097/MPG.0000000000001384) (PMID:27540707)

Simpson, J. H., McKerracher, L., Cooper, A., Barnett, D., Gentles, E., Cairns, L. and Gerasimidis, K. (2016) Optimal distribution and utilization of donated human breast milk: a novel approach. Journal of Human Lactation, 32(4), pp. 730-734. (doi:10.1177/0890334416653738) (PMID:27364932) (PMCID:PMC5060945)

Gerasimidis, K. , Ijaz, U. Z., Edwards, C. , Russell, R. K., Quince, C. and Hansen, R. (2016) Response to Kaakoush et al. American Journal of Gastroenterology, 111(7), pp. 1033-1034. (doi:10.1038/ajg.2016.169) (PMID:27356826)

Chourdakis, M. et al. (2016) Malnutrition risk in hospitalised children: use of 3 screening tools in a large European population. American Journal of Clinical Nutrition, 103(5), pp. 1301-1310. (doi:10.3945/ajcn.115.110700)

Svolos, V., Hansen, R., Hughes, K., Ijaz, U.Z., Quince, C., Gaya, D., Russell, R. and Gerasimidis, K. (2016) The Impact of ‘Crohn’s Disease-TReatment-with-EATing’ Diet (CD-TREAT Diet) and Exclusive Enteral Nutrition on Healthy Gut Bacteria Metabolism. 11th Congress of the European Crohn's and Colitis Organisation, Amsterdam, The Netherlands, 16-19 March 2016. S14-S15. (doi:10.1093/ecco-jcc/jjw019.017)

Gerasimidis, K. , Bertz, M., Quince, C., Brunner, K., Bruce, A., Combet, E. , Calus, S., Loman, N. and Ijaz, U. (2016) The effect of DNA extraction methodology on gut microbiota research applications. BMC Research Notes, 9, 365. (doi:10.1186/s13104-016-2171-7) (PMID:27456340) (PMCID:PMC4960752)

Khan, M. J., Gerasimidis, K. , Edwards, C. A. and Shaikh, M. G. (2016) Role of gut microbiota in the aetiology of obesity: proposed mechanisms and review of the literature. Journal of Obesity, 2016, 7353642. (doi:10.1155/2016/7353642) (PMID:7703805) (PMCID:PMC5040794)

2015

Fatima, S., Gerasimidis, K. , Wright, C. , Tsiountsioura, M., Arvanitidou, E.-I. and Malkova, D. (2015) Response of appetite and potential appetite regulators following intake of high energy nutritional supplements. Appetite, 95, pp. 36-43. (doi:10.1016/j.appet.2015.06.010) (PMID:26119811)

Quince, C. et al. (2015) Extensive modulation of the fecal metagenome in children with Crohn’s Disease during exclusive enteral nutrition. American Journal of Gastroenterology, 110, pp. 1718-1729. (doi:10.1038/ajg.2015.357) (PMID:26526081)

McKechnie, J. and Gerasimidis, K. (2015) Visual inspection is not a substitute for anthropometry in screening for nutritional status and growth in sick children. Acta Paediatrica, 104(8), e375-e377. (doi:10.1111/apa.13011) (PMID:25808932)

Androutsos, O., Gerasimidis, K. , Karanikolou, A., Reilly, J.J. and Edwards, C.A. (2015) Impact of eating and drinking on body composition measurements by bioelectrical impedance. Journal of Human Nutrition and Dietetics, 28(2), pp. 165-171. (doi:10.1111/jhn.12259) (PMID:25158295)

Khan, M. J. et al. (2015) A Detailed Analysis of the Gut Microbial Diversity and Metabolic Activity in Children with Obesity of Different Aetiology and Lean Controls. The Nutrition Society Summer Meeting: Carbohydrates in Health: Friends or Foes?, Glasgow, UK, 14-17 Jul 2014. (doi:10.1017/S0029665115000907)

2014

Cochrane, B., Schwahn, B., Galloway, P., Robinson, P. and Gerasimidis, K. (2014) A questionnaire survey on the usage of low protein staple foods by people with phenylketonuria in Scotland. Journal of Human Nutrition and Dietetics, 27(6), pp. 533-541. (doi:10.1111/jhn.12199)

Gentles, E., Mara, J., Diamantidi, K., Alfheeaid, H. A., Spenceley, N., Davidson, M. and Gerasimidis, K. (2014) Delivery of enteral nutrition after the introduction of practice guidelines and participation of dietitians in pediatric critical care clinical teams. Journal of the Academy of Nutrition and Dietics, 114(12), 1974-U359. (doi:10.1016/j.jand.2014.04.027)

Gerasimidis, K. , Loman, N., Quick, J., Calus, S., Ijaz, U., McGrogan, P., Edwards, C.A. , Quince, C. and Russell, R.K. (2014) Metagenomic Analysis of the Gut Microbiome During a Course of Exclusive Enteral Nutrition (EEN) Provides Novel Insights on Mechanism of EEN Action. 3rd International Symposium on Pediatric Inflammatory Bowel Disease, Rotterdam, The Netherlands, 10-13 Sept 2014. S393-S394. (doi:10.1016/S1873-9946(14)50003-7)

Mara, J., Gentles, E., Alfheeaid, H. A., Diamantidi, K., Spenceley, N., Davidson, M., Young, D. and Gerasimidis, K. (2014) An evaluation of enteral nutrition practices and nutritional provision in children during the entire length of stay in critical care. BMC Pediatrics, 14(1), p. 186. (doi:10.1186/1471-2431-14-186)

Gerasimidis, K. , Russell, R., Hansen, R., Quince, C., Loman, N., Bertz, M., Hanske, L., Blaut, M., McGrogan, P. and Edwards, C. A. (2014) Role of Faecalibacterium prausnitzii in Crohnʼs Disease. Inflammatory Bowel Diseases, 20(7), E18-E19. (doi:10.1097/MIB.0000000000000079)

Tsiountsioura, M. et al. (2014) Detailed assessment of nutritional status and eating patterns in children with gastrointestinal diseases attending an outpatients clinic and contemporary healthy controls. European Journal of Clinical Nutrition, 68(6), pp. 700-706. (doi:10.1038/ejcn.2013.286)

Gerasimidis, K. , Maclean, A. and Wright, C. (2014) Malnutrition screening tools need to be applied properly before they can be compared. Acta Paediatrica, 103(3), e94. (doi:10.1111/apa.12506)

Hecht, C. et al. (2014) Disease associated malnutrition correlates with length of hospital stay in children. Clinical Nutrition, 34(1), pp. 53-59. (doi:10.1016/j.clnu.2014.01.003)

Gerasimidis, K. , Shepherd, S., Rashid, R., Edwards, C.A. and Ahmed, F. (2014) Group and individual agreement between field and dual x-ray absorptiometry–based body composition techniques in children from standard schools and a sports academy. Journal of the Academy of Nutrition and Dietics, 114(1), pp. 91-98. (doi:10.1016/j.jand.2013.06.353)

Khan, M.J., Svolos, V., Cheng, S., Shaikh, G.M., Quince, C., Edwards, C.A. and Gerasimidis, K. (2014) Unraveling the role of the gut microbiota in obesity; cause or effect? Proceedings of the Nutrition Society, 73(OCE1), E18. (doi:10.1017/S0029665114000329)

Gerasimidis, K. (2014) Inflammatory bowel disease nutritional consequences. In: Lomer, M. (ed.) Advanced Nutrition and Dietetics in Gastroenterology. Series: Advanced nutrition and dietetics. John Wiley & Sons Ltd., pp. 180-190. ISBN 9780470671320 (doi:10.1002/9781118872796.ch3.13)

Gerasimidis, K. et al. (2014) Decline in presumptively protective gut bacterial species and metabolites are paradoxically associated with disease improvement in pediatric crohn’s disease during enteral nutrition. Inflammatory Bowel Diseases, (doi:10.1097/MIB.0000000000000023)

Mackinder, M. et al. (2014) Nutritional status, growth and disease management in children with single and dual diagnosis of type 1 diabetes mellitus and coeliac disease. BMC Gastroenterology, 14(99), (doi:10.1186/1471-230X-14-99)