2025

Parveen, Humaira, Boder, Philipp, Mullen, William ORCID: https://orcid.org/0000-0002-5685-1563, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Van Agtmael, Tom ORCID: https://orcid.org/0000-0003-4282-449X, Rampoldi, Luca, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020 (2025) Early renal response to long term salt loading: Mitochondrial dysfunction, ER stress and uromodulin accumulation in the kidney medulla. American Journal of Physiology: Renal Physiology, (Accepted for Publication)

Alves-Lopes, Rheure ORCID: https://orcid.org/0000-0002-4885-6647, Neves, Karla B., Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Montezano, Augusto C., Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Touyz, Rhian ORCID: https://orcid.org/0000-0003-0670-0887 (2025) Salt-induced vascular damage in hypertension involves redox activation of PARP/TRPM2 signalling and inflammasome assembly. American Journal of Hypertension, (doi: 10.1093/ajh/hpaf071) (PMID:40312994) (Accepted for Publication)

2024

Beazer, J. D. et al. (2024) Favourable HDL composition in endurance athletes is not associated with changes in HDL in vitro antioxidant and endothelial anti-inflammatory function. Bioscience Reports, 44(10), BSR20241165-BSR20241165. (doi: 10.1042/BSR20241165) (PMID:39344511) (PMCID:PMC11499383)

Zhou, Manshi, Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612, Padmanabhan, Sandosh ORCID: https://orcid.org/0000-0003-3869-5808, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Dominiczak, Anna ORCID: https://orcid.org/0000-0003-4913-3608 (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0) (PMID:39259220) (Early Online Publication)

McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, 105315. (doi: 10.1016/j.ebiom.2024.105315) (PMID:39216230) (PMCID:PMC11402910)

Olivera, Sol and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2024) Modelling pre-eclampsia and its cardiovascular effects. Nature Reviews Cardiology, 21, 281. (doi: 10.1038/s41569-024-01006-0) (PMID:38480793)

Mary, S. et al. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6) (PMID:38236469) (Early Online Publication)

McFall, Aisling ORCID: https://orcid.org/0000-0002-4368-8330, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 and Work, Lorraine M. ORCID: https://orcid.org/0000-0002-6462-4109 (2024) Unscheduled changes in pre-clinical stroke model housing contributes to variance in physiological and behavioural data outcomes: a post hoc analysis. Brain and Neuroscience Advances, 8, (doi: 10.1177/23982128241238934) (PMID:38516557) (PMCID:PMC10956152)

2023

Cui, L. et al. (2023) Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing. Genome Biology, 24(1), 215. (doi: 10.1186/s13059-023-03060-2) (PMID:37773188) (PMCID:PMC10540365)

Olivera, Sol and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2023) Sex differences in preclinical models of hypertension. Journal of Human Hypertension, 37(8), pp. 619-625. (doi: 10.1038/s41371-022-00770-1) (PMID:36335169)

2022

Kumar, A. A. et al. (2022) Vascular collagen type-IV in hypertension and cerebral small vessel disease. Stroke, 53(12), pp. 3696-3705. (doi: 10.1161/STROKEAHA.122.037761) (PMID:36205142) (PMCID:PMC9698121)

Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Padmanabhan, Sandosh ORCID: https://orcid.org/0000-0003-3869-5808, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888) (PMID:36378920) (PMCID:PMC9553220)

2021

Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Rossitto, Giacomo, Graham, Lesley ORCID: https://orcid.org/0000-0002-3901-5213, Scott, Kayley, Flynn, Arun, Kipgen, David, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)

Alves-Lopes, R. et al. (2021) Selective inhibition of the C-domain of ACE (angiotensin-converting enzyme) combined with inhibition of NEP (neprilysin): a potential new therapy for hypertension. Hypertension, 78(3), pp. 604-616. (doi: 10.1161/HYPERTENSIONAHA.121.17041) (PMID:34304582) (PMCID:PMC8357049)

Patanapirunhakit, Patamat, Karlsson, Helen, Mulder, Monique, Ljunggren, Stefan, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Freeman, Dilys ORCID: https://orcid.org/0000-0002-6078-5271 (2021) Sphingolipids in HDL – potential markers for adaptation to pregnancy? Biochimica et Biophysica Acta: Molecular and Cell Biology of Lipids, 1866(8), 158955. (doi: 10.1016/j.bbalip.2021.158955) (PMID:33933650)

Scott, Kayley ORCID: https://orcid.org/0000-0001-8641-6821, Morgan, Hannah L., Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612, Fisher, Simon, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53(4), pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020) (PMID:33719581)

2020

Beazer, Jack David ORCID: https://orcid.org/0000-0001-6978-3072, Patanapirunhakit, Patamat, Gill, Jason M.R. ORCID: https://orcid.org/0000-0003-3615-0986, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Karlsson, Helen, Ljunggren, Stefan, Mulder, Monique and Freeman, Dilys J. ORCID: https://orcid.org/0000-0002-6078-5271 (2020) High-density lipoprotein’s vascular protective functions in metabolic and cardiovascular disease - could extracellular vesicles be at play? Clinical Science, 134(22), pp. 2977-2986. (doi: 10.1042/CS20200892) (PMID:33210708)

Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Frazier, Sonya, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Mulvana, Helen and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2020) From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia. Clinical Science, 134(8), pp. 1001-1025. (doi: 10.1042/CS20200023) (PMID:32337535) (PMCID:PMC7239341)

2019

Czesnikiewicz-Guzik, Marta ORCID: https://orcid.org/0000-0002-7444-1373, Nosalski, Ryszard, Mikolajczyk, Tomasz P., Vidler, Francesca, Dohnal, Tomasz, Dembowska, Elzbieta, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Harrison, David G. and Guzik, Tomasz J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)

Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)

Olson, Erin, Pravenec, Michal, Landa, Vladimir, Koh-Tan, Han Hui Caline, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2019) Transgenic overexpression of glutathione S-transferase μ-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 37(5), pp. 985-996. (doi: 10.1097/HJH.0000000000001960) (PMID:30308595)

Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2019) Vascular physiology. In: Touyz, Rhian M. and Delles, Christian (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 13-22. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_2)

2018

Graham, Lesley A. ORCID: https://orcid.org/0000-0002-3901-5213, Aman, Alisha ORCID: https://orcid.org/0000-0003-4022-5880, Campbell, Desmond D. ORCID: https://orcid.org/0000-0003-1085-714X, Augley, Julian, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Fraser, Niall J., Ferreri, Nicholas R., Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 and Padmanabhan, Sandosh ORCID: https://orcid.org/0000-0003-3869-5808 (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50(11), pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018) (PMID:30216136) (PMCID:PMC6293113)

Divorty, Nina, Milligan, Graeme ORCID: https://orcid.org/0000-0002-6946-3519, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 (2018) The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice. American Journal of Hypertension, 31(9), pp. 1049-1058. (doi: 10.1093/ajh/hpy073) (PMID:29860395) (PMCID:PMC6077831)

Rajani, R. M. et al. (2018) Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats. Science Translational Medicine, 10(448), eaam9507. (doi: 10.1126/scitranslmed.aam9507) (PMID:29973407)

De Lucca Camargo, L. et al. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72(1), pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824) (PMID:29844144) (PMCID:PMC6004120)

Morgan, Hannah L., Butler, Elaine, Ritchie, Shona, Herse, Florian, Dechend, Ralf, Beattie, Elisabeth, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2018) Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats. Hypertension, 72(1), pp. 208-218. (doi: 10.1161/HYPERTENSIONAHA.118.10935) (PMID:29844145) (PMCID:PMC6012051)

Bailey, Emma ORCID: https://orcid.org/0000-0003-3826-9956, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, McClure, John D. ORCID: https://orcid.org/0000-0003-4839-5462, Beattie, Wendy, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, Anna ORCID: https://orcid.org/0000-0003-4913-3608, Smith, Colin and Wardlaw, Joanna (2018) Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease. Clinical Science, 132(12), pp. 1315-1328. (doi: 10.1042/CS20171572) (PMID:29632138) (PMCID:PMC6365623)

Montezano, A. C. et al. (2018) NADPH oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7(12), e009388. (doi: 10.1161/JAHA.118.009388) (PMID:29907654) (PMCID:PMC6220544)

Montezano, A. C. et al. (2018) NADPH Oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7(12), (doi: 10.1161/JAHA.118.009388) (PMID:29907654) (PMCID:PMC6220544)

Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612, Carrick, Emma, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15(7), pp. 581-592. (doi: 10.1080/14789450.2018.1493927) (PMID:29999442) (PMCID:PMC6092739)

2017

Harvey, Adam P., Montezano, Augusto C., Hood, Katie Y., Lopes, Rheure A. ORCID: https://orcid.org/0000-0002-4885-6647, Rios, Francisco ORCID: https://orcid.org/0000-0002-8194-0787, Ceravolo, Graziela, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Touyz, Rhian M. ORCID: https://orcid.org/0000-0003-0670-0887 (2017) Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis. Life Sciences, 179, pp. 110-119. (doi: 10.1016/j.lfs.2017.05.002) (PMID:28478264) (PMCID:5446265)

Koh-Tan, H.H. Caline, Dashti, Mohammed, Wang, Ting, Beattie, Wendy, Mcclure, John ORCID: https://orcid.org/0000-0003-4839-5462, Young, Barbara, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35(2), pp. 319-329. (doi: 10.1097/HJH.0000000000001155) (PMID:27755386) (PMCID:PMC5214373)

Mancini, Sarah J., White, Anna D., Bijland, Silvia, Rutherford, Claire, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Richter, Erik A., Viollet, Benoit, Touyz, Rhian M. ORCID: https://orcid.org/0000-0003-0670-0887, Palmer, Timothy M. and Salt, Ian P. ORCID: https://orcid.org/0000-0003-0055-3724 (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010) (PMID:27840174) (PMCID:PMC5228585)

2016

Small, Heather Yvonne, Nosalski, Ryszard, Morgan, Hannah, Beattie, Elisabeth, Guzik, Tomasz, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68(5), pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933) (PMID:27733586) (PMCID:PMC5058643)

Morgan, H., Small, H.Y., Beattie, E., McBride, M.W. ORCID: https://orcid.org/0000-0002-6323-124X and Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708 (2016) [OP.5D.02] Transcriptomic changes in early pregnancy-associated uterine artery remodelling in stroke prone spontaneously hypertensive rat. Journal of Hypertension, 34(S2), e63-e63. (doi: 10.1097/01.hjh.0000491501.79443.05) (PMID:27508758)

Wan Sulaiman, W.N., Caslake, M.J., Delles, C. ORCID: https://orcid.org/0000-0003-2238-2612, Karlsson, H., Mulder, M.T., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708 and Freeman, D.J. ORCID: https://orcid.org/0000-0002-6078-5271 (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130(7), pp. 491-497. (doi: 10.1042/cs20150475) (PMID:26888561)

Small, Heather Y., Morgan, Hannah, Beattie, Elisabeth, Griffin, Sinead, Indahl, Marie, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022) (PMID:26612342) (PMCID:PMC4721537)

2015

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892) (PMID:26243800)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544) (PMID:26034203) (PMCID:PMC4490909)

Skogstrand, Trude, Leh, Sabine, McClure, John ORCID: https://orcid.org/0000-0003-4839-5462, Dashti, Mohammed, Iversen, Bjarne M., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin ORCID: https://orcid.org/0000-0002-6323-124X and Hultström, Michael (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33(3), pp. 584-596. (doi: 10.1097/HJH.0000000000000395) (PMID:25380151)

Lopez, L. M. et al. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46(2), pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649) (PMID:25586835) (PMCID:PMC4306534)

2014

Lee, Kit M., Danuser, Renzo, Stein, Jens V., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Nibbs, Robert J.B. ORCID: https://orcid.org/0000-0002-8150-0044 and Graham, Gerard J. ORCID: https://orcid.org/0000-0002-7801-204X (2014) The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density. EMBO Journal, 33(21), pp. 2564-2580. (doi: 10.15252/embj.201488887)

Sampson, Amanda K., Mohammed, Dashti, Beattie, Wendy, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Kenyon, Christopher J., Al-Dujaili, Emad A.S., Guryev, Victor, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (2014) Introgressed chromosome 2 quantitative trait loci restores aldosterone regulation and reduces response to salt in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 32(10), pp. 2013-2021. (doi: 10.1097/HJH.0000000000000300)

Graham, L. A. et al. (2014) Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension, 63(3), pp. 551-558. (doi: 10.1161/HYPERTENSIONAHA.113.01423)

McLachlan, Jennifer, Beattie, Elisabeth, Murphy, Michael P., Koh-Tan, Caline H.H., Olson, Erin, Beattie, Wendy, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2014) Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function. Journal of Hypertension, 32(3), pp. 555-564. (doi: 10.1097/HJH.0000000000000054)

Bailey, Emma L. ORCID: https://orcid.org/0000-0003-3826-9956, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Crawford, Wendy, McClure, John D. ORCID: https://orcid.org/0000-0003-4839-5462, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, Sudlow, Cathie L.M., Smith, Colin and Wardlaw, Joanna M. (2014) Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke. Neuropathology and Applied Neurobiology, 40(7), pp. 855-872. (doi: 10.1111/nan.12116)

Baud, A. et al. (2014) Genomes and phenomes of a population of outbred rats and its progenitors. Scientific Data, 1, 140011. (doi: 10.1038/sdata.2014.11) (PMID:25977769) (PMCID:PMC4381735)

Padmanabhan, Sandosh ORCID: https://orcid.org/0000-0003-3869-5808, Graham, Lesley ORCID: https://orcid.org/0000-0002-3901-5213, Ferreri, Nicholas R., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin ORCID: https://orcid.org/0000-0002-6323-124X and Dominiczak, Anna ORCID: https://orcid.org/0000-0003-4913-3608 (2014) Uromodulin, an emerging novel pathway for blood pressure regulation and hypertension. Hypertension, 64(5), pp. 918-923. (doi: 10.1161/HYPERTENSIONAHA.114.03132)

Sampson, Amanda K., Andrews, Karen L., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Head, Geoffrey A., Thomas, Merlin C., Chin-Dusting, Jaye P.F., Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 and Jennings, Garry L. (2014) Origin of the y chromosome influences intrarenal vascular responsiveness to angiotensin i and angiotensin (1-7) in stroke-prone spontaneously hypertensive rats. Hypertension, 64(6), pp. 1376-1383. (doi: 10.1161/HYPERTENSIONAHA.114.03756)

2013

Montezano, Augusto C., Yusuf, Hiba, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Touyz, Rhian M. ORCID: https://orcid.org/0000-0003-0670-0887 (2013) Redox-sensitive osteogenic factors as novel mediators of vascular injury in hypertension. Hypertension, 62(3 Sup), A490.

Baud, A. et al. (2013) Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nature Genetics, 45(7), pp. 767-775. (doi: 10.1038/ng.2644)

Brittain, J.F. et al. (2013) An MRI-histological study of white matter in stroke-free SHRSP. Journal of Cerebral Blood Flow and Metabolism, 33(5), pp. 760-763. (doi: 10.1038/jcbfm.2013.14)

Koh-Tan, H.H. Caline, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, McClure, John D. ORCID: https://orcid.org/0000-0003-4839-5462, Beattie, Elisabeth, Young, Barbara, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2013) Interaction between chromosome 2 and 3 regulates pulse pressure in the stroke-prone spontaneously hypertensive rat. Hypertension, 62(1), pp. 33-40. (doi: 10.1161/HYPERTENSIONAHA.111.00814)

Tarr, D., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Roy, L.A., Holmes, W.M. ORCID: https://orcid.org/0000-0002-0942-215X, McCabe, C. ORCID: https://orcid.org/0000-0003-3111-031X, Macrae, I.M., Muir, K.W. ORCID: https://orcid.org/0000-0001-9535-022X and Dewar, D. ORCID: https://orcid.org/0000-0002-8388-2779 (2013) Hyperglycemia accelerates apparent diffusion coefficient-defined lesion growth after focal cerebral ischemia in rats with and without features of metabolic syndrome. Journal of Cerebral Blood Flow and Metabolism, 33(10), pp. 1556-1563. (doi: 10.1038/jcbfm.2013.107)

2012

Xu, H. et al. (2012) Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension. Cardiovascular Research, 96(3), pp. 552-560. (doi: 10.1093/cvr/cvs273) (PMID:22918977) (PMCID:PMC3500047)

Reid, Emma ORCID: https://orcid.org/0000-0002-2555-438X, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Lopez-Gonzalez, M. Rosario, Holmes, William M. ORCID: https://orcid.org/0000-0002-0942-215X, Macrae, I. Mhairi and McCabe, Chris ORCID: https://orcid.org/0000-0003-3111-031X (2012) Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods. Journal of Cerebral Blood Flow and Metabolism, 32(9), pp. 1765-1777. (doi: 10.1038/jcbfm.2012.69) (PMID:22669479) (PMCID:PMC3434632)

Flores, M., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608, Milligan, G. ORCID: https://orcid.org/0000-0002-6946-3519, Baker, A.H. and Nicklin, S.A. ORCID: https://orcid.org/0000-0002-9691-6210 (2012) Angiotensin-(1-9) antagonises Angiotensin II-induced cardiac remodeling via the angiotensin type 2 receptor. Proceedings of the Physiological Society, 27, C1.

Flores, M., Work, L.M. ORCID: https://orcid.org/0000-0002-6462-4109, Douglas, K., Denby, L., Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608, Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708 and Nicklin, S.A. ORCID: https://orcid.org/0000-0002-9691-6210 (2012) Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension, 59(2), pp. 300-307. (doi: 10.1161/HYPERTENSIONAHA.111.177485)

Flores, Monica, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, Milligan, Graeme ORCID: https://orcid.org/0000-0002-6946-3519, Baker, Andrew H. and Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 (2012) Abstract 231: angiotensin-(1-9) antagonises cardiac remodelling in a mouse model of Angiotensin Ii-induced hypertension. Hypertension, 60, A231.

2011

Bailey, E.L. ORCID: https://orcid.org/0000-0003-3826-9956, Wardlaw, J.M., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608, Sudlow, C.L.M. and Smith, C. (2011) Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats. Neuropathology and Applied Neurobiology, 37(7), pp. 711-726. (doi: 10.1111/j.1365-2990.2011.01170.x)

Yogi, A., Callera, G.E., Aranha, A.B., Antunes, T.T., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, McBride, M. ORCID: https://orcid.org/0000-0002-6323-124X, Dominiczak, A. ORCID: https://orcid.org/0000-0003-4913-3608 and Touyz, R.M. ORCID: https://orcid.org/0000-0003-0670-0887 (2011) Sphingosine-1-Phosphate-Induced Inflammation Involves Receptor Tyrosine Kinase Transactivation in Vascular Cells: Upregulation in Hypertension. Hypertension, 57(4), pp. 809-818. (doi: 10.1161/HYPERTENSIONAHA.110.162719)

2010

Greig, J.A., Shirley, R., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Denby, L., Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608, Work, L.M. ORCID: https://orcid.org/0000-0002-6462-4109 and Baker, A. (2010) Vascular-targeting anti-oxidant therapy in a model of hypertension and stroke. Journal of Cardiovascular Pharmacology, 56(6), pp. 642-650. (doi: 10.1097/FJC.0b013e3181f8f19f)

Hopcroft, Lisa E.M. ORCID: https://orcid.org/0000-0002-7022-1322, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Harris, Keith J., Sampson, Amanda K., McClure, John D. ORCID: https://orcid.org/0000-0003-4839-5462, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Young, Graham, Holyoake, Tessa L., Girolami, Mark A. and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (2010) Predictive response-relevant clustering of expression data provides insights into disease processes. Nucleic Acids Research, 38(20), pp. 6831-6840. (doi: 10.1093/nar/gkq550)

Delles, C. ORCID: https://orcid.org/0000-0003-2238-2612, McBride, M.W. ORCID: https://orcid.org/0000-0002-6323-124X, Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Padmanabhan, S. ORCID: https://orcid.org/0000-0003-3869-5808 and Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608 (2010) Genetics of hypertension: from experimental animals to humans. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802(12), pp. 1299-1308. (doi: 10.1016/j.bbadis.2009.12.006)

Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Koh-Tan, H. H. C. and Dominiczak, A. F. ORCID: https://orcid.org/0000-0003-4913-3608 (2010) Reduced renal glutathione S-transferase mu type 1 expression in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 28(3), p. 634. (doi: 10.1097/HJH.0b013e328336902d)

McBride, M. ORCID: https://orcid.org/0000-0002-6323-124X, Hopcroft, L. ORCID: https://orcid.org/0000-0002-7022-1322, Harris, K., McClure, J. ORCID: https://orcid.org/0000-0003-4839-5462, Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Girolami, M. and Dominiczak, M. (2010) Insights into Salt-Sensitive Hypertension Using Response-Relevant Clustering. In: 20th Annual Meeting of the European Society of Hypertension, Oslo, Norway, 18-21 June, E342-E342.

McCabe, C. ORCID: https://orcid.org/0000-0003-3111-031X, Gallagher, L., Macrae, I.M., Gsell, W., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708 and Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608 (2010) Response to letter by Yao (Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats). Stroke, 41(4), E198-E199. (doi: 10.1161/STROKEAHA.109.575704)

Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6(10), e1001177. (doi: 10.1371/journal.pgen.1001177)

2009

McCabe, Christopher ORCID: https://orcid.org/0000-0003-3111-031X, Gallagher, Lindsay, Gsell, Willy, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 and Macrae, I. Mhairi (2009) Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Stroke, 40(12), pp. 3864-3868. (doi: 10.1161/STROKEAHA.109.559021)

Graham, D., Huynh, N.N., Hamilton, C.A., Beattie, E.C., Smith, R.A.J., Cocheme, H.M., Murphy, M.P. and Dominiczak, A.F. (2009) Mitochondria-targeted antioxidant MitoQ(10) improves endothelial function and attenuates cardiac hypertrophy. Hypertension, 54(2), 322-U233. (doi: 10.1161/HYPERTENSIONAHA.109.130351)

Johannesson, M. et al. (2009) A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: The NIH heterogeneous stock. Genome Research, 19(1), pp. 150-158. (doi: 10.1101/gr.081497.108)

Koh-Tan, HC, Graham, D ORCID: https://orcid.org/0000-0002-7328-4708, Hamilton, CA, Nicoll, G, Fields, L, McBride, MW ORCID: https://orcid.org/0000-0002-6323-124X, Young, BC, Young, B and Dominiczak, AF ORCID: https://orcid.org/0000-0003-4913-3608 (2009) Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. Journal of Hypertension, 27(8), pp. 1575-1584. (doi: 10.1097/HJH.0b013e32832cc5a1)

Masson, R. et al. (2009) Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2. Hypertension, 53(4), pp. 694-700. (doi: 10.1161/HYPERTENSIONAHA.108.122333)

Xu, A., Chamberlain, J., Francis, S., Brookes, Z., Shaw, G., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Alp, N.J., Dower, S. and Crossman, D.C. (2009) Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding. PLoS ONE, 4(4), e5073. (doi: 10.1371/journal.pone.0005073) (PMID:19347044) (PMCID:PMC2661361)

2008

Miller, WH, Graham, D, Douglas, K, MacKenzie, RM and Dominiczak, AF ORCID: https://orcid.org/0000-0003-4913-3608 (2008) Metabolic phenotypes in SHRSP and chromosome 2 congenic strains. Journal of Human Hypertension, 22(10), pp. 736-737.

Miller, WH, Graham, D ORCID: https://orcid.org/0000-0002-7328-4708, Douglas, K, Mackenzie, R, Huynh, N and Dominiczak, AF ORCID: https://orcid.org/0000-0003-4913-3608 (2008) Characterisation of metabolic phenotypes in the SHRSP using chromosome 2 congenic strains. Journal of Hypertension, 26(Suppl.), S340-S341.

Tian, T., McBride, M.W., Graham, D., Touyz, R. ORCID: https://orcid.org/0000-0003-0670-0887 and Dominiczak, A.F. (2008) A systems biology approach for the sphingosine-1-phosphate signal transduction in vascular smooth muscle cell. Journal of Hypertension, 26(Suppl.), S148-S148.

Tonyz, R, Aranha, A, Yogi, A, Graham, D, McBride, MW, Callera, G, Montezano, A, Coimbra, T and Dominiczak, AF (2008) Increased vascular sphingosine-1-phosphate signaling in SHRSP is due to post-receptor mechanisms. Journal of Hypertension, 26(Suppl.), S329-S329.

2007

Graham, D. et al. (2007) Candidate genes that determine response to salt in the stroke-prone spontaneously hypertensive rat - Congenic analysis. Hypertension, 50(6), pp. 1134-1141. (doi: 10.1161/HYPERTENSIONAHA.107.095349)

2005

Dominiczak, Anna F., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Brain, Nick J.R., Lee, Wai Kwong ORCID: https://orcid.org/0000-0001-8560-8063, Charchar, Fadi J., Tomaszewski, Maciej, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Hamilton, Carlene A. (2005) Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension, 45(4), pp. 636-642. (doi: 10.1161/01.HYP.0000154253.53134.09)

2004

McBride, M.W. ORCID: https://orcid.org/0000-0002-6323-124X, Charchar, F.J., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Miller, W.H. ORCID: https://orcid.org/0000-0002-1362-2883, Strahorn, P., Carr, F.J. and Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608 (2004) Functional genomics in rodent models of hypertension. Journal of Physiology, 554(1), pp. 56-63. (doi: 10.1113/jphysiol.2003.049361)

Denby, L., Work, L.M., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Hsu, C., Von Seggern, D.J., Nicklin, S.A. and Baker, A.H. (2004) Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo. Human Gene Therapy, 15(11), pp. 1054-1064.

1999

Anderson, Niall H., Devlin, Alison M., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Morton, James J., Hamilton, Carlene A., Reid, John L., Schork, Nicholas J. and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (1999) Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis. Hypertension, 33(1), pp. 248-255. (doi: 10.1161/01.HYP.33.1.248) (PMID:9931112)

1998

Devlin, Alison M., Brosnan, M. Julia, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Morton, James J., McPhaden, Allan R., McIntyre, Martin, Hamilton, Carlene A., Reid, John L. and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (1998) Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo. American Journal of Physiology: Heart and Circulatory Physiology, 274(1), H52-H59. (PMID:9458851)

1997

Dominiczak, A. F. ORCID: https://orcid.org/0000-0003-4913-3608, Devlin, A. M., Brosnan, M. J., Anderson, N. H., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Clark, J. S., McPhaden, A., Hamilton, C. A. and Reid, J. L. (1997) Left ventricular hypertrophy and arterial blood pressure in experimental models of hypertension. Advances in Experimental Medicine and Biology, 432, pp. 23-33. (doi: 10.1007/978-1-4615-5385-4_3) (PMID:9433508)

Articles

Parveen, Humaira, Boder, Philipp, Mullen, William ORCID: https://orcid.org/0000-0002-5685-1563, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Van Agtmael, Tom ORCID: https://orcid.org/0000-0003-4282-449X, Rampoldi, Luca, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020 (2025) Early renal response to long term salt loading: Mitochondrial dysfunction, ER stress and uromodulin accumulation in the kidney medulla. American Journal of Physiology: Renal Physiology, (Accepted for Publication)

Alves-Lopes, Rheure ORCID: https://orcid.org/0000-0002-4885-6647, Neves, Karla B., Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Montezano, Augusto C., Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Touyz, Rhian ORCID: https://orcid.org/0000-0003-0670-0887 (2025) Salt-induced vascular damage in hypertension involves redox activation of PARP/TRPM2 signalling and inflammasome assembly. American Journal of Hypertension, (doi: 10.1093/ajh/hpaf071) (PMID:40312994) (Accepted for Publication)

Beazer, J. D. et al. (2024) Favourable HDL composition in endurance athletes is not associated with changes in HDL in vitro antioxidant and endothelial anti-inflammatory function. Bioscience Reports, 44(10), BSR20241165-BSR20241165. (doi: 10.1042/BSR20241165) (PMID:39344511) (PMCID:PMC11499383)

Zhou, Manshi, Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612, Padmanabhan, Sandosh ORCID: https://orcid.org/0000-0003-3869-5808, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Dominiczak, Anna ORCID: https://orcid.org/0000-0003-4913-3608 (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0) (PMID:39259220) (Early Online Publication)

McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, 105315. (doi: 10.1016/j.ebiom.2024.105315) (PMID:39216230) (PMCID:PMC11402910)

Olivera, Sol and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2024) Modelling pre-eclampsia and its cardiovascular effects. Nature Reviews Cardiology, 21, 281. (doi: 10.1038/s41569-024-01006-0) (PMID:38480793)

Mary, S. et al. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6) (PMID:38236469) (Early Online Publication)

McFall, Aisling ORCID: https://orcid.org/0000-0002-4368-8330, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 and Work, Lorraine M. ORCID: https://orcid.org/0000-0002-6462-4109 (2024) Unscheduled changes in pre-clinical stroke model housing contributes to variance in physiological and behavioural data outcomes: a post hoc analysis. Brain and Neuroscience Advances, 8, (doi: 10.1177/23982128241238934) (PMID:38516557) (PMCID:PMC10956152)

Cui, L. et al. (2023) Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing. Genome Biology, 24(1), 215. (doi: 10.1186/s13059-023-03060-2) (PMID:37773188) (PMCID:PMC10540365)

Olivera, Sol and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2023) Sex differences in preclinical models of hypertension. Journal of Human Hypertension, 37(8), pp. 619-625. (doi: 10.1038/s41371-022-00770-1) (PMID:36335169)

Kumar, A. A. et al. (2022) Vascular collagen type-IV in hypertension and cerebral small vessel disease. Stroke, 53(12), pp. 3696-3705. (doi: 10.1161/STROKEAHA.122.037761) (PMID:36205142) (PMCID:PMC9698121)

Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Padmanabhan, Sandosh ORCID: https://orcid.org/0000-0003-3869-5808, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888) (PMID:36378920) (PMCID:PMC9553220)

Mary, Sheon ORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Rossitto, Giacomo, Graham, Lesley ORCID: https://orcid.org/0000-0002-3901-5213, Scott, Kayley, Flynn, Arun, Kipgen, David, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)

Alves-Lopes, R. et al. (2021) Selective inhibition of the C-domain of ACE (angiotensin-converting enzyme) combined with inhibition of NEP (neprilysin): a potential new therapy for hypertension. Hypertension, 78(3), pp. 604-616. (doi: 10.1161/HYPERTENSIONAHA.121.17041) (PMID:34304582) (PMCID:PMC8357049)

Patanapirunhakit, Patamat, Karlsson, Helen, Mulder, Monique, Ljunggren, Stefan, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Freeman, Dilys ORCID: https://orcid.org/0000-0002-6078-5271 (2021) Sphingolipids in HDL – potential markers for adaptation to pregnancy? Biochimica et Biophysica Acta: Molecular and Cell Biology of Lipids, 1866(8), 158955. (doi: 10.1016/j.bbalip.2021.158955) (PMID:33933650)

Scott, Kayley ORCID: https://orcid.org/0000-0001-8641-6821, Morgan, Hannah L., Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612, Fisher, Simon, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53(4), pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020) (PMID:33719581)

Beazer, Jack David ORCID: https://orcid.org/0000-0001-6978-3072, Patanapirunhakit, Patamat, Gill, Jason M.R. ORCID: https://orcid.org/0000-0003-3615-0986, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Karlsson, Helen, Ljunggren, Stefan, Mulder, Monique and Freeman, Dilys J. ORCID: https://orcid.org/0000-0002-6078-5271 (2020) High-density lipoprotein’s vascular protective functions in metabolic and cardiovascular disease - could extracellular vesicles be at play? Clinical Science, 134(22), pp. 2977-2986. (doi: 10.1042/CS20200892) (PMID:33210708)

Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)

Nosalski, R. et al. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428) (PMID:32065054) (PMCID:PMC7147427)

Frazier, Sonya, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Mulvana, Helen and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2020) From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia. Clinical Science, 134(8), pp. 1001-1025. (doi: 10.1042/CS20200023) (PMID:32337535) (PMCID:PMC7239341)

Czesnikiewicz-Guzik, Marta ORCID: https://orcid.org/0000-0002-7444-1373, Nosalski, Ryszard, Mikolajczyk, Tomasz P., Vidler, Francesca, Dohnal, Tomasz, Dembowska, Elzbieta, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Harrison, David G. and Guzik, Tomasz J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176(12), pp. 1922-1931. (doi: 10.1111/bph.14536) (PMID:30414380) (PMCID:PMC6534780)

Mikolajczyk, T. P. et al. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176(12), pp. 1951-1965. (doi: 10.1111/bph.14583) (PMID:30658013) (PMCID:PMC6534792)

Olson, Erin, Pravenec, Michal, Landa, Vladimir, Koh-Tan, Han Hui Caline, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2019) Transgenic overexpression of glutathione S-transferase μ-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 37(5), pp. 985-996. (doi: 10.1097/HJH.0000000000001960) (PMID:30308595)

Graham, Lesley A. ORCID: https://orcid.org/0000-0002-3901-5213, Aman, Alisha ORCID: https://orcid.org/0000-0003-4022-5880, Campbell, Desmond D. ORCID: https://orcid.org/0000-0003-1085-714X, Augley, Julian, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Fraser, Niall J., Ferreri, Nicholas R., Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 and Padmanabhan, Sandosh ORCID: https://orcid.org/0000-0003-3869-5808 (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50(11), pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018) (PMID:30216136) (PMCID:PMC6293113)

Divorty, Nina, Milligan, Graeme ORCID: https://orcid.org/0000-0002-6946-3519, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 (2018) The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice. American Journal of Hypertension, 31(9), pp. 1049-1058. (doi: 10.1093/ajh/hpy073) (PMID:29860395) (PMCID:PMC6077831)

Rajani, R. M. et al. (2018) Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats. Science Translational Medicine, 10(448), eaam9507. (doi: 10.1126/scitranslmed.aam9507) (PMID:29973407)

De Lucca Camargo, L. et al. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72(1), pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824) (PMID:29844144) (PMCID:PMC6004120)

Morgan, Hannah L., Butler, Elaine, Ritchie, Shona, Herse, Florian, Dechend, Ralf, Beattie, Elisabeth, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2018) Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats. Hypertension, 72(1), pp. 208-218. (doi: 10.1161/HYPERTENSIONAHA.118.10935) (PMID:29844145) (PMCID:PMC6012051)

Bailey, Emma ORCID: https://orcid.org/0000-0003-3826-9956, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, McClure, John D. ORCID: https://orcid.org/0000-0003-4839-5462, Beattie, Wendy, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, Anna ORCID: https://orcid.org/0000-0003-4913-3608, Smith, Colin and Wardlaw, Joanna (2018) Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease. Clinical Science, 132(12), pp. 1315-1328. (doi: 10.1042/CS20171572) (PMID:29632138) (PMCID:PMC6365623)

Montezano, A. C. et al. (2018) NADPH oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7(12), e009388. (doi: 10.1161/JAHA.118.009388) (PMID:29907654) (PMCID:PMC6220544)

Montezano, A. C. et al. (2018) NADPH Oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7(12), (doi: 10.1161/JAHA.118.009388) (PMID:29907654) (PMCID:PMC6220544)

Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612, Carrick, Emma, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15(7), pp. 581-592. (doi: 10.1080/14789450.2018.1493927) (PMID:29999442) (PMCID:PMC6092739)

Harvey, Adam P., Montezano, Augusto C., Hood, Katie Y., Lopes, Rheure A. ORCID: https://orcid.org/0000-0002-4885-6647, Rios, Francisco ORCID: https://orcid.org/0000-0002-8194-0787, Ceravolo, Graziela, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Touyz, Rhian M. ORCID: https://orcid.org/0000-0003-0670-0887 (2017) Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis. Life Sciences, 179, pp. 110-119. (doi: 10.1016/j.lfs.2017.05.002) (PMID:28478264) (PMCID:5446265)

Koh-Tan, H.H. Caline, Dashti, Mohammed, Wang, Ting, Beattie, Wendy, Mcclure, John ORCID: https://orcid.org/0000-0003-4839-5462, Young, Barbara, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35(2), pp. 319-329. (doi: 10.1097/HJH.0000000000001155) (PMID:27755386) (PMCID:PMC5214373)

Mancini, Sarah J., White, Anna D., Bijland, Silvia, Rutherford, Claire, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Richter, Erik A., Viollet, Benoit, Touyz, Rhian M. ORCID: https://orcid.org/0000-0003-0670-0887, Palmer, Timothy M. and Salt, Ian P. ORCID: https://orcid.org/0000-0003-0055-3724 (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010) (PMID:27840174) (PMCID:PMC5228585)

Small, Heather Yvonne, Nosalski, Ryszard, Morgan, Hannah, Beattie, Elisabeth, Guzik, Tomasz, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68(5), pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933) (PMID:27733586) (PMCID:PMC5058643)

Morgan, H., Small, H.Y., Beattie, E., McBride, M.W. ORCID: https://orcid.org/0000-0002-6323-124X and Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708 (2016) [OP.5D.02] Transcriptomic changes in early pregnancy-associated uterine artery remodelling in stroke prone spontaneously hypertensive rat. Journal of Hypertension, 34(S2), e63-e63. (doi: 10.1097/01.hjh.0000491501.79443.05) (PMID:27508758)

Wan Sulaiman, W.N., Caslake, M.J., Delles, C. ORCID: https://orcid.org/0000-0003-2238-2612, Karlsson, H., Mulder, M.T., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708 and Freeman, D.J. ORCID: https://orcid.org/0000-0002-6078-5271 (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130(7), pp. 491-497. (doi: 10.1042/cs20150475) (PMID:26888561)

Small, Heather Y., Morgan, Hannah, Beattie, Elisabeth, Griffin, Sinead, Indahl, Marie, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022) (PMID:26612342) (PMCID:PMC4721537)

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892) (PMID:26243800)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544) (PMID:26034203) (PMCID:PMC4490909)

Skogstrand, Trude, Leh, Sabine, McClure, John ORCID: https://orcid.org/0000-0003-4839-5462, Dashti, Mohammed, Iversen, Bjarne M., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin ORCID: https://orcid.org/0000-0002-6323-124X and Hultström, Michael (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33(3), pp. 584-596. (doi: 10.1097/HJH.0000000000000395) (PMID:25380151)

Lopez, L. M. et al. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46(2), pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649) (PMID:25586835) (PMCID:PMC4306534)

Lee, Kit M., Danuser, Renzo, Stein, Jens V., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Nibbs, Robert J.B. ORCID: https://orcid.org/0000-0002-8150-0044 and Graham, Gerard J. ORCID: https://orcid.org/0000-0002-7801-204X (2014) The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density. EMBO Journal, 33(21), pp. 2564-2580. (doi: 10.15252/embj.201488887)

Sampson, Amanda K., Mohammed, Dashti, Beattie, Wendy, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Kenyon, Christopher J., Al-Dujaili, Emad A.S., Guryev, Victor, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (2014) Introgressed chromosome 2 quantitative trait loci restores aldosterone regulation and reduces response to salt in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 32(10), pp. 2013-2021. (doi: 10.1097/HJH.0000000000000300)

Graham, L. A. et al. (2014) Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension, 63(3), pp. 551-558. (doi: 10.1161/HYPERTENSIONAHA.113.01423)

McLachlan, Jennifer, Beattie, Elisabeth, Murphy, Michael P., Koh-Tan, Caline H.H., Olson, Erin, Beattie, Wendy, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2014) Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function. Journal of Hypertension, 32(3), pp. 555-564. (doi: 10.1097/HJH.0000000000000054)

Bailey, Emma L. ORCID: https://orcid.org/0000-0003-3826-9956, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Crawford, Wendy, McClure, John D. ORCID: https://orcid.org/0000-0003-4839-5462, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, Sudlow, Cathie L.M., Smith, Colin and Wardlaw, Joanna M. (2014) Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke. Neuropathology and Applied Neurobiology, 40(7), pp. 855-872. (doi: 10.1111/nan.12116)

Baud, A. et al. (2014) Genomes and phenomes of a population of outbred rats and its progenitors. Scientific Data, 1, 140011. (doi: 10.1038/sdata.2014.11) (PMID:25977769) (PMCID:PMC4381735)

Padmanabhan, Sandosh ORCID: https://orcid.org/0000-0003-3869-5808, Graham, Lesley ORCID: https://orcid.org/0000-0002-3901-5213, Ferreri, Nicholas R., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin ORCID: https://orcid.org/0000-0002-6323-124X and Dominiczak, Anna ORCID: https://orcid.org/0000-0003-4913-3608 (2014) Uromodulin, an emerging novel pathway for blood pressure regulation and hypertension. Hypertension, 64(5), pp. 918-923. (doi: 10.1161/HYPERTENSIONAHA.114.03132)

Sampson, Amanda K., Andrews, Karen L., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Head, Geoffrey A., Thomas, Merlin C., Chin-Dusting, Jaye P.F., Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 and Jennings, Garry L. (2014) Origin of the y chromosome influences intrarenal vascular responsiveness to angiotensin i and angiotensin (1-7) in stroke-prone spontaneously hypertensive rats. Hypertension, 64(6), pp. 1376-1383. (doi: 10.1161/HYPERTENSIONAHA.114.03756)

Montezano, Augusto C., Yusuf, Hiba, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 and Touyz, Rhian M. ORCID: https://orcid.org/0000-0003-0670-0887 (2013) Redox-sensitive osteogenic factors as novel mediators of vascular injury in hypertension. Hypertension, 62(3 Sup), A490.

Baud, A. et al. (2013) Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nature Genetics, 45(7), pp. 767-775. (doi: 10.1038/ng.2644)

Brittain, J.F. et al. (2013) An MRI-histological study of white matter in stroke-free SHRSP. Journal of Cerebral Blood Flow and Metabolism, 33(5), pp. 760-763. (doi: 10.1038/jcbfm.2013.14)

Koh-Tan, H.H. Caline, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, McClure, John D. ORCID: https://orcid.org/0000-0003-4839-5462, Beattie, Elisabeth, Young, Barbara, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 and Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2013) Interaction between chromosome 2 and 3 regulates pulse pressure in the stroke-prone spontaneously hypertensive rat. Hypertension, 62(1), pp. 33-40. (doi: 10.1161/HYPERTENSIONAHA.111.00814)

Tarr, D., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Roy, L.A., Holmes, W.M. ORCID: https://orcid.org/0000-0002-0942-215X, McCabe, C. ORCID: https://orcid.org/0000-0003-3111-031X, Macrae, I.M., Muir, K.W. ORCID: https://orcid.org/0000-0001-9535-022X and Dewar, D. ORCID: https://orcid.org/0000-0002-8388-2779 (2013) Hyperglycemia accelerates apparent diffusion coefficient-defined lesion growth after focal cerebral ischemia in rats with and without features of metabolic syndrome. Journal of Cerebral Blood Flow and Metabolism, 33(10), pp. 1556-1563. (doi: 10.1038/jcbfm.2013.107)

Xu, H. et al. (2012) Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension. Cardiovascular Research, 96(3), pp. 552-560. (doi: 10.1093/cvr/cvs273) (PMID:22918977) (PMCID:PMC3500047)

Reid, Emma ORCID: https://orcid.org/0000-0002-2555-438X, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Lopez-Gonzalez, M. Rosario, Holmes, William M. ORCID: https://orcid.org/0000-0002-0942-215X, Macrae, I. Mhairi and McCabe, Chris ORCID: https://orcid.org/0000-0003-3111-031X (2012) Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods. Journal of Cerebral Blood Flow and Metabolism, 32(9), pp. 1765-1777. (doi: 10.1038/jcbfm.2012.69) (PMID:22669479) (PMCID:PMC3434632)

Flores, M., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608, Milligan, G. ORCID: https://orcid.org/0000-0002-6946-3519, Baker, A.H. and Nicklin, S.A. ORCID: https://orcid.org/0000-0002-9691-6210 (2012) Angiotensin-(1-9) antagonises Angiotensin II-induced cardiac remodeling via the angiotensin type 2 receptor. Proceedings of the Physiological Society, 27, C1.

Flores, M., Work, L.M. ORCID: https://orcid.org/0000-0002-6462-4109, Douglas, K., Denby, L., Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608, Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708 and Nicklin, S.A. ORCID: https://orcid.org/0000-0002-9691-6210 (2012) Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor. Hypertension, 59(2), pp. 300-307. (doi: 10.1161/HYPERTENSIONAHA.111.177485)

Flores, Monica, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608, Milligan, Graeme ORCID: https://orcid.org/0000-0002-6946-3519, Baker, Andrew H. and Nicklin, Stuart A. ORCID: https://orcid.org/0000-0002-9691-6210 (2012) Abstract 231: angiotensin-(1-9) antagonises cardiac remodelling in a mouse model of Angiotensin Ii-induced hypertension. Hypertension, 60, A231.

Bailey, E.L. ORCID: https://orcid.org/0000-0003-3826-9956, Wardlaw, J.M., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608, Sudlow, C.L.M. and Smith, C. (2011) Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats. Neuropathology and Applied Neurobiology, 37(7), pp. 711-726. (doi: 10.1111/j.1365-2990.2011.01170.x)

Yogi, A., Callera, G.E., Aranha, A.B., Antunes, T.T., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, McBride, M. ORCID: https://orcid.org/0000-0002-6323-124X, Dominiczak, A. ORCID: https://orcid.org/0000-0003-4913-3608 and Touyz, R.M. ORCID: https://orcid.org/0000-0003-0670-0887 (2011) Sphingosine-1-Phosphate-Induced Inflammation Involves Receptor Tyrosine Kinase Transactivation in Vascular Cells: Upregulation in Hypertension. Hypertension, 57(4), pp. 809-818. (doi: 10.1161/HYPERTENSIONAHA.110.162719)

Greig, J.A., Shirley, R., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Denby, L., Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608, Work, L.M. ORCID: https://orcid.org/0000-0002-6462-4109 and Baker, A. (2010) Vascular-targeting anti-oxidant therapy in a model of hypertension and stroke. Journal of Cardiovascular Pharmacology, 56(6), pp. 642-650. (doi: 10.1097/FJC.0b013e3181f8f19f)

Hopcroft, Lisa E.M. ORCID: https://orcid.org/0000-0002-7022-1322, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Harris, Keith J., Sampson, Amanda K., McClure, John D. ORCID: https://orcid.org/0000-0003-4839-5462, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Young, Graham, Holyoake, Tessa L., Girolami, Mark A. and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (2010) Predictive response-relevant clustering of expression data provides insights into disease processes. Nucleic Acids Research, 38(20), pp. 6831-6840. (doi: 10.1093/nar/gkq550)

Delles, C. ORCID: https://orcid.org/0000-0003-2238-2612, McBride, M.W. ORCID: https://orcid.org/0000-0002-6323-124X, Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Padmanabhan, S. ORCID: https://orcid.org/0000-0003-3869-5808 and Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608 (2010) Genetics of hypertension: from experimental animals to humans. Biochimica et Biophysica Acta: Molecular Basis of Disease, 1802(12), pp. 1299-1308. (doi: 10.1016/j.bbadis.2009.12.006)

Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Koh-Tan, H. H. C. and Dominiczak, A. F. ORCID: https://orcid.org/0000-0003-4913-3608 (2010) Reduced renal glutathione S-transferase mu type 1 expression in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 28(3), p. 634. (doi: 10.1097/HJH.0b013e328336902d)

McCabe, C. ORCID: https://orcid.org/0000-0003-3111-031X, Gallagher, L., Macrae, I.M., Gsell, W., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708 and Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608 (2010) Response to letter by Yao (Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats). Stroke, 41(4), E198-E199. (doi: 10.1161/STROKEAHA.109.575704)

Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6(10), e1001177. (doi: 10.1371/journal.pgen.1001177)

McCabe, Christopher ORCID: https://orcid.org/0000-0003-3111-031X, Gallagher, Lindsay, Gsell, Willy, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 and Macrae, I. Mhairi (2009) Differences in the evolution of the ischemic penumbra in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. Stroke, 40(12), pp. 3864-3868. (doi: 10.1161/STROKEAHA.109.559021)

Graham, D., Huynh, N.N., Hamilton, C.A., Beattie, E.C., Smith, R.A.J., Cocheme, H.M., Murphy, M.P. and Dominiczak, A.F. (2009) Mitochondria-targeted antioxidant MitoQ(10) improves endothelial function and attenuates cardiac hypertrophy. Hypertension, 54(2), 322-U233. (doi: 10.1161/HYPERTENSIONAHA.109.130351)

Johannesson, M. et al. (2009) A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: The NIH heterogeneous stock. Genome Research, 19(1), pp. 150-158. (doi: 10.1101/gr.081497.108)

Koh-Tan, HC, Graham, D ORCID: https://orcid.org/0000-0002-7328-4708, Hamilton, CA, Nicoll, G, Fields, L, McBride, MW ORCID: https://orcid.org/0000-0002-6323-124X, Young, BC, Young, B and Dominiczak, AF ORCID: https://orcid.org/0000-0003-4913-3608 (2009) Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. Journal of Hypertension, 27(8), pp. 1575-1584. (doi: 10.1097/HJH.0b013e32832cc5a1)

Masson, R. et al. (2009) Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2. Hypertension, 53(4), pp. 694-700. (doi: 10.1161/HYPERTENSIONAHA.108.122333)

Xu, A., Chamberlain, J., Francis, S., Brookes, Z., Shaw, G., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Alp, N.J., Dower, S. and Crossman, D.C. (2009) Interleukin-1 regulates multiple atherogenic mechanisms in response to fat feeding. PLoS ONE, 4(4), e5073. (doi: 10.1371/journal.pone.0005073) (PMID:19347044) (PMCID:PMC2661361)

Miller, WH, Graham, D, Douglas, K, MacKenzie, RM and Dominiczak, AF ORCID: https://orcid.org/0000-0003-4913-3608 (2008) Metabolic phenotypes in SHRSP and chromosome 2 congenic strains. Journal of Human Hypertension, 22(10), pp. 736-737.

Miller, WH, Graham, D ORCID: https://orcid.org/0000-0002-7328-4708, Douglas, K, Mackenzie, R, Huynh, N and Dominiczak, AF ORCID: https://orcid.org/0000-0003-4913-3608 (2008) Characterisation of metabolic phenotypes in the SHRSP using chromosome 2 congenic strains. Journal of Hypertension, 26(Suppl.), S340-S341.

Tian, T., McBride, M.W., Graham, D., Touyz, R. ORCID: https://orcid.org/0000-0003-0670-0887 and Dominiczak, A.F. (2008) A systems biology approach for the sphingosine-1-phosphate signal transduction in vascular smooth muscle cell. Journal of Hypertension, 26(Suppl.), S148-S148.

Tonyz, R, Aranha, A, Yogi, A, Graham, D, McBride, MW, Callera, G, Montezano, A, Coimbra, T and Dominiczak, AF (2008) Increased vascular sphingosine-1-phosphate signaling in SHRSP is due to post-receptor mechanisms. Journal of Hypertension, 26(Suppl.), S329-S329.

Graham, D. et al. (2007) Candidate genes that determine response to salt in the stroke-prone spontaneously hypertensive rat - Congenic analysis. Hypertension, 50(6), pp. 1134-1141. (doi: 10.1161/HYPERTENSIONAHA.107.095349)

Dominiczak, Anna F., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID: https://orcid.org/0000-0002-6323-124X, Brain, Nick J.R., Lee, Wai Kwong ORCID: https://orcid.org/0000-0001-8560-8063, Charchar, Fadi J., Tomaszewski, Maciej, Delles, Christian ORCID: https://orcid.org/0000-0003-2238-2612 and Hamilton, Carlene A. (2005) Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension, 45(4), pp. 636-642. (doi: 10.1161/01.HYP.0000154253.53134.09)

McBride, M.W. ORCID: https://orcid.org/0000-0002-6323-124X, Charchar, F.J., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Miller, W.H. ORCID: https://orcid.org/0000-0002-1362-2883, Strahorn, P., Carr, F.J. and Dominiczak, A.F. ORCID: https://orcid.org/0000-0003-4913-3608 (2004) Functional genomics in rodent models of hypertension. Journal of Physiology, 554(1), pp. 56-63. (doi: 10.1113/jphysiol.2003.049361)

Denby, L., Work, L.M., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Hsu, C., Von Seggern, D.J., Nicklin, S.A. and Baker, A.H. (2004) Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo. Human Gene Therapy, 15(11), pp. 1054-1064.

Anderson, Niall H., Devlin, Alison M., Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Morton, James J., Hamilton, Carlene A., Reid, John L., Schork, Nicholas J. and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (1999) Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis. Hypertension, 33(1), pp. 248-255. (doi: 10.1161/01.HYP.33.1.248) (PMID:9931112)

Devlin, Alison M., Brosnan, M. Julia, Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708, Morton, James J., McPhaden, Allan R., McIntyre, Martin, Hamilton, Carlene A., Reid, John L. and Dominiczak, Anna F. ORCID: https://orcid.org/0000-0003-4913-3608 (1998) Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo. American Journal of Physiology: Heart and Circulatory Physiology, 274(1), H52-H59. (PMID:9458851)

Dominiczak, A. F. ORCID: https://orcid.org/0000-0003-4913-3608, Devlin, A. M., Brosnan, M. J., Anderson, N. H., Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Clark, J. S., McPhaden, A., Hamilton, C. A. and Reid, J. L. (1997) Left ventricular hypertrophy and arterial blood pressure in experimental models of hypertension. Advances in Experimental Medicine and Biology, 432, pp. 23-33. (doi: 10.1007/978-1-4615-5385-4_3) (PMID:9433508)

Book Sections

Graham, Delyth ORCID: https://orcid.org/0000-0002-7328-4708 (2019) Vascular physiology. In: Touyz, Rhian M. and Delles, Christian (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 13-22. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_2)

Conference Proceedings

McBride, M. ORCID: https://orcid.org/0000-0002-6323-124X, Hopcroft, L. ORCID: https://orcid.org/0000-0002-7022-1322, Harris, K., McClure, J. ORCID: https://orcid.org/0000-0003-4839-5462, Graham, D. ORCID: https://orcid.org/0000-0002-7328-4708, Girolami, M. and Dominiczak, M. (2010) Insights into Salt-Sensitive Hypertension Using Response-Relevant Clustering. In: 20th Annual Meeting of the European Society of Hypertension, Oslo, Norway, 18-21 June, E342-E342.