Pregnancy Complications

Pregnancy is a period of substantial change in cardiovascular physiology. Understanding the mechanisms and consequences of these changes can help us detect and treat pathology in pregnancy and can also help us better understand cardiovascular disease in general. 

Staff

Publications

2024

Lang, N., Rankin, S., Elyan, B., Jones, R., Venugopal, B., Mark, P. B., Lees, J., Petrie, M., Lang, N. (2024) Cardiovascular eligibility criteria and adverse event reporting in combined immune checkpoint and VEGF inhibitors trials. JACC: CardioOncology, 6, pp. 267-279. (doi: 10.1016/j.jaccao.2023.12.010)

Carberry, J., Petrie, M. C., Lee, M. M.Y., Brooksbank, K., Campbell, R. T., Good, R., Jhund, P. S., Kellman, P., Lang, N. N., Mangion, K., Mark, P. B., McConnachie, A., McMurray, J. J.V., Meyer, B., Orchard, V., Shaukat, A., Watkins, S., Welsh, P., Sattar, N., Berry, C., Docherty, K. F. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure,

Hanson Ng, Y. Y., Dora, K. A., Lemmey, H. A. L., Lin, J., Alden, J., Wallis, L., Donovan, L., Shorthose, O., Leiper, F. C., Leiper, J., Garland, C. J. (2024) Asymmetric dimethylarginine enables depolarizing spikes and vasospasm in mesenteric and coronary resistance arteries. Hypertension, 81, pp. 764-775. (doi: 10.1161/HYPERTENSIONAHA.123.22454)

Lim, M. W. S., Lucas-Herald, A. K., Mason, A., Delles, C., Connelly, P. J. (2024) Sex differences in the cardiovascular effects of GnRH analogues. Journal of Endocrinology, 261, (doi: 10.1530/JOE-23-0309)

Docherty, K. F., McMurray, J. J.V., Kalra, P., Cleland, J. G.F., Lang, N. N., Petrie, M. C., Robertson, M., Ford, I. (2024) Intravenous iron and SGLT2 inhibitors in iron-deficient patients with heart failure and reduced ejection fraction. ESC Heart Failure, (doi: 10.1002/ehf2.14742)

Kobayashi, M., Ferreira, J. P., Kevin, D., Bresso, E., Huttin, O., Bozec, E., Brunner La Rocca, H.-P., Delles, C., Clark, A. L., Edelmann, F., González, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A.J., Rossignol, P., Cleland, J. G.F., Zannad, F., Girerd, N. (2024) Proteomic profiles of left atrial volume and its influence on response to spironolactone: findings from the HOMAGE trial and STANISLAS cohort. European Journal of Heart Failure,

Tomaz, S. A., Taylor, L., Ryde, G. C., Bradwell, H. L., Cooper, L., Coffee, P., Mannion, G., Hennessy, C., Haynes, R., Whittaker, A. C. (2024) Generations Active Together: an example of using physical activity promotion and digital technology to bring together adolescents and older people in Stirling, Scotland. Journal of Intergenerational Relationships, (doi: 10.1080/15350770.2024.2322442)

Deo, S. V., Al-Kindi, S., Motairek, I., McAllister, D., Shah, A. S.V., Elgudin, Y. E., Gorodeski, E. Z., Virani, S., Petrie, M. C., Rajagopalan, S., Sattar, N. (2024) Impact of residential social deprivation on prediction of heart failure in patients with type 2 diabetes: External validation and recalibration of the WATCH-DM score using real world data. Circulation: Cardiovascular Quality and Outcomes, 17, pp. 267-276. (doi: 10.1161/circoutcomes.123.010166)

Osmanska, J., Petrie, M. C., Campbell, R. T. (2024) Reply: subcutaneous furosemide patch: heart failure decongestion "from the comfort of your home" European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae015)

Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M., Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics: Salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.17942)

Campbell, P., Rutten, F. H., Lee, M. M. Y., Hawkins, N. M., Petrie, M. C. (2024) Heart failure with preserved ejection fraction: Everything the clinician needs to know. Lancet, (doi: 10.1016/S0140-6736(23)02756-3)

Butt, J. H., McDowell, K., Kondo, T., Desai, A. S., Lefkowitz, M. P., Packer, M., Petrie, M. C., Pfeffer, M. A., Rouleau, J. L., Vaduganathan, M., Zile, M. R., Jhund, P. S., Køber, L., Solomon, S., McMurray, J. J.V. (2024) Heart failure with preserved ejection fraction, red cell distribution width, and sacubitril/valsartan. ESC Heart Failure, 11, pp. 65-77. (doi: 10.1002/ehf2.14558)

Olowoyo, P. et al. (2024) Priorities to reduce the burden of hypertension in Africa through ACHIEVE. Lancet Global Health, 12, pp. e192-e193. (doi: 10.1016/S2214-109X(23)00540-5)

Jackson, A. M., Goland, S., Farhan, H. A., Yaseen, I. F., Prameswari, H. S., Böhm, M., Jhund, P. S., Maggioni, A. P., van der Meer, P., Sliwa, K., Bauersachs, J., Petrie, M. C. (2024) A novel score to predict left ventricular recovery in peripartum cardiomyopathy derived from the ESC EORP Peripartum Cardiomyopathy Registry. European Heart Journal, (doi: 10.1093/eurheartj/ehad888)

Swales, B., Ryde, G. C., Whittaker, A. C. (2024) A mixed methods feasibility study of machine-based resistance training with prefrail older adults in residential care: the keeping active in residential elderly trial II. Journal of Aging and Physical Activity, (doi: 10.1123/japa.2022-0170)

Omerovic, E., Petrie, M., Redfors, B., Fremes, S., Murphy, G., Marquis-Gravel, G., Lansky, A., Velazquez, E., Perera, D., Reid, C., Smith, J., van der Meer, P., Lipsic, E., Juni, P., McMurray, J., Bauersachs, J., Køber, L., Rouleau, J. L., Doenst, T. (2024) Pragmatic randomized controlled trials: strengthening the concept through a robust international collaborative network: PRIME-9-pragmatic research and innovation through multinational experimentation. Trials, 25, (doi: 10.1186/s13063-024-07935-y)

Petrie, M. C., Rouleau, J. L., Claggett, B., Jering, K., van der Meer, P., Køber, L., Miao, Z. M., Lewis, E., Granger, C., De Pasqulae, C. G., Mann, D., Steg, P. G., Maggioni, A., Amir, O., Lefkowitz, M., Braunwald, E., Solomon, S. D., McMurray, J. J. V., Pfeffer, M. A. (2024) Pulmonary congestion and left ventricular dysfunction after myocardial infarction: insights from the PARADISE-MI trial. Circulation, 149, pp. 335-38. (doi: 10.1161/CIRCULATIONAHA.123.066163)

Mary, S., Conti-Ramsden, F., Boder, P., Parveen, H., Setjiadi, D., Fleminger, J., Brockbank, A., Graham, D., Bramham, K., Chappell, L. C., Delles, C. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6)

Kharlamov, A., Sherriff, N., Delles, C., van der Harst, P. (2024) Tackling cardiovascular healthcare disparities for LGBTQIA+ population: a call to action in the European Society of Cardiology. European Heart Journal, (doi: 10.1093/eurheartj/ehad882)

Lee, M. M.Y., Kondo, T., Campbell, R. T., Petrie, M. C., Sattar, N., Solomon, S. D., Vaduganathan, M., Jhund, P. S., McMurray, J. J.V. (2024) Effects of Renin-Angiotensin system blockers on outcomes from COVID-19: a systematic review and meta-analysis of randomised controlled trials. European Heart Journal: Cardiovascular Pharmacotherapy, 10, pp. 68-80. (doi: 10.1093/ehjcvp/pvad067)

Chivardi, C. et al. (2024) Percutaneous revascularization for ischemic left ventricular dysfunction: Cost-effectiveness analysis of the REVIVED-BCIS2 trial. Circulation: Cardiovascular Quality and Outcomes, 17, (doi: 10.1161/circoutcomes.123.010533)

McFall, A., Graham, D., Nicklin, S. A., Work, L. M. (2024) Unscheduled changes in pre-clinical stroke model housing contributes to variance in physiological and behavioural data outcomes: a post hoc analysis. Brain and Neuroscience Advances, 8, (doi: 10.1177/23982128241238934)

2023

Lee, M. M.Y., Lean, M. E.J., Sattar, N., Petrie, M. C. (2023) Appetite and its regulation: Are there palatable interventions for heart failure? Current Heart Failure Reports, 21, pp. 1-4. (doi: 10.1007/s11897-023-00637-7)

Glen, C., Morrow, A., Roditi, G., Hopkins, T., Macpherson, I., Stewart, P., Petrie, M. C., Berry, C., Epstein, F., Lang, N. N., Mangion, K. (2023) Cardiovascular sequalae of trastuzumab and anthracycline in long-term survivors of breast cancer. Heart, (doi: 10.1136/heartjnl-2023-323437)

Bagordo, D., Rossi, G. P., Delles, C., Wiig, H., Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569)

Neupane, D., Mukhtar, Q., Krajan Pardo, E. K., Acharya, S. D., Delles, C., Sharman, J. E., Cobb, L., Lackland, D. T., Moran, A., Weber, M. A., Olsen, M. H. (2023) Emerging Authors Program for building cardiovascular disease prevention and management research capacity in low- and middle-income countries: a collaboration of the U.S. Centers for Disease Control and Prevention, the Lancet Commission on Hypertension Group, Resolve to Save Lives, and the World Hypertension League. Journal of Human Hypertension, pp. -023. (doi: 10.1038/s41371-023-00880-4)

Swales, B., Ryde, G. C., Fletcher, I., Whittaker, A. C. (2023) The reliability and suitability of strength assessments in frail and pre-frail older adults: Recommendations for strength testing in older populations. BMC Geriatrics, 23, (doi: 10.1186/s12877-023-04552-3)

Connelly, P., Osmanska, J., Lee, M. M.Y., Delles, C., McEntegart, M. B., Byrne, J. (2023) A case report of myocardial infarction in a young transgender man with testosterone therapy? raising awareness on healthcare issues in the transgender community and a call for further research. European Heart Journal: Case Reports, 7, (doi: 10.1093/ehjcr/ytad562)

Zahir Anjum, D., Strange, J. E., Fosbøl, E., Garred, C. H., Malik, M. E., Andersson, C., Jhund, P. S., McMurray, J. J.V., Petrie, M. C., Kober, L., Schou, M. (2023) Initiation of medical therapy for heart failure patients according to kidney function: a Danish nationwide study. Clinical Epidemiology, 15, pp. 855-866. (doi: 10.2147/clep.s412787)

Bradwell, H. L., Cooper, L., Edwards, K. J., Baxter, R., Tomaz, S. A., Ritchie, J., Gaudl, S., Veliz-Reyes, A., Ryde, G. C., Križaj, T., Warren, A., Chatterjee, A., Willis, K., Haynes, R., Hennessy, C. H., Whittaker, A. C., Asthana, S., Jones, R. B. (2023) Staff perceptions towards virtual reality-motivated treadmill exercise for care home residents: a qualitative feedback study with key stakeholders and follow-up interview with technology developer. BMJ Open, 13, (doi: 10.1136/bmjopen-2023-073307)

Desson, Z., Sharman, J. E., Searles, A., Schutte, A. E., Delles, C., Olsen, M. H., Ordunez, P., Hure, A., Morton, R., Figtree, G., Webster, J., Jennings, G., Redfern, J., Nicolls, S., McNamara, M., Deeming, S., Doyle, K., Ramanathan, S. (2023) Improving the accuracy of blood pressure measuring devices in Australia: a modelled return on investment study. Journal of Human Hypertension, (doi: 10.1038/s41371-023-00866-2)

McDowell, K., Adamson, C., Jackson, C., Campbell, R., Welsh, P., Petrie, M. C., McMurray, J. J.V., Jhund, P., Herring, N. (2023) Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes. European Journal of Heart Failure, (doi: 10.1002/ejhf.3085)

Ray, R., Ford, I., Cleland, J. G.F., Graham, F., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Critoph, C., Kalra, P. A., Lane, R. E., Ludman, A., Pellicori, P., Petrie, M. C., Robertson, M., Seed, A., Squire, I., Kalra, P. R. (2023) The impact of ferric derisomaltose on cardiovascular and non-cardiovascular events in patients with anemia, iron deficiency and heart failure with reduced ejection fraction. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2023.10.006)

Murphy, C. N., Delles, C., Davies, E., Connelly, P. J. (2023) Cardiovascular disease in transgender individuals. Atherosclerosis, 384, (doi: 10.1016/j.atherosclerosis.2023.117282)

Irshad, Z., Lund, J., Sillars, A., Løvsletten, N. G., Gharanei, S., Salt, I. P., Freeman, D. J., Gill, J. M.R., Thoresen, G. H., Rustan, A. C., Zammit, V. A. (2023) The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho-physiological background. FASEB Journal, 37, (doi: 10.1096/fj.202300960RR)

Glen, C., Adam, S., McDowell, K., Waterston, A., Tan, Y. Y., Petrie, M. C., Coats, C. J., Lang, N. N. (2023) Cardiotoxicity of BRAF/MEK inhibitors: a longitudinal study incorporating contemporary definitions and risk scores. JACC: CardioOncology, 5, pp. 628-637. (doi: 10.1016/j.jaccao.2023.04.004)

Jackson, A., Bauersachs, J., Petrie, M. C., van der Meer, P., Laroche, C., Farhan, H. A., Frogoudaki, A., Ibrahim, B., Fouad, D. A., Damasceno, A., Karaye, K., Goland, S., Maggioni, A. P., Briton, O., Sliwa, K. (2023) Outcomes at one year in women with peripartum cardiomyopathy: findings from the ESC EORP PPCM Registry. European Journal of Heart Failure, (doi: 10.1002/ejhf.3055)

Jackson, A. M., Macartney, M., Brooksbank, K., Brown, C., Dawson, D., Francis, M., Japp, A., Lennie, V., Leslie, S. J., Martin, T., Neary, P., Venakatasubramanian, S., Vickers, D., Weir, R. A., McMurray, J. J.V., Jhund, P. S., Petrie, M. C. (2023) A 20-year population study of peripartum cardiomyopathy. European Heart Journal, (doi: 10.1093/eurheartj/ehad626)

Osmanska, J., Brooksbank, K., Docherty, K. F., Robertson, S., Wetherall, K., McConnachie, A., Hu, J., Gardner, R. S., Clark, A. L., Squire, I. B., Kalra, P. R., Jhund, P. S., Muntendam, P., McMurray, J. J.V., Petrie, M. C., Campbell, R. T. (2023) A novel, small-volume subcutaneous furosemide formulation delivered by an abdominal patch infusor device in patients with heart failure: results of two phase I studies. European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvad073)

Malik, M. E., Butt, J. H., Strange, J. E., Falkentoft, A. C., Jensen, J., Andersson, C., Zahir, D., Fosbøl, E., Petrie, M. C., Sattar, N., McMurray, J. J.V., Køber, L., Schou, M. (2023) Initiation of SGLT2 inhibitors and GLP-1 receptor agonists according to level of frailty in people with type 2 diabetes and cardiovascular disease in Denmark: a cross-sectional, nationwide study. Lancet Healthy Longevity, 4, pp. e552-e560. (doi: 10.1016/S2666-7568(23)00164-2)

Meyer, B. J., Cortie, C., Dekker-Nitert, M., Barrett, H. L., Freeman, D. J. (2023) Women with gestational diabetes mellitus, controlled for plasma glucose level, exhibit maternal and fetal dyslipidaemia that may warrant treatment. Diabetes Research and Clinical Practice, 204, (doi: 10.1016/j.diabres.2023.110929)

Perera, D. et al. (2023) Arrhythmia and death following percutaneous revascularization in ischemic left ventricular dysfunction: Prespecified analyses from the REVIVED-BCIS2 trial. Circulation: Heart Failure, 148, pp. 862-871. (doi: 10.1161/circulationaha.123.065300)

de Beer, D., MC. Mels, C., Schutte, A., Delles, C., Mary, S., Mullen, W., Mischak, H., Kruger, R. (2023) Urinary peptidomics and pulse wave velocity: The African-PREDICT study. Journal of Proteome Research, 22, pp. 3282-3289. (doi: 10.1021/acs.jproteome.3c00347)

Montezano, A. C., Camargo, L. L., Mary, S., Neves, K. B., Rios, F. J., Stein, R., Lopes, R. A., Beattie, W., Thomson, J., Herder, V., Szemiel, A. M., McFarlane, S., Palmarini, M., Touyz, R. (2023) SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication. Scientific Reports, 13, (doi: 10.1038/s41598-023-41115-3)

Borlaug, B. A. et al. (2023) Semaglutide in HFpEF across obesity class and by body weight reduction: a prespecified analysis of the STEP-HFpEF trial. Nature Medicine, 29, pp. 2358-2365. (doi: 10.1038/s41591-023-02526-x)

Harrington, J., Udell, J. A., Jones, W. S., Anker, S. D., Bhatt, D. L., Petrie, M. C., Andersen, K. R., Sumin, M., Zwiener, I., Hernandez, A. F., Butler, J. (2023) Baseline characteristics of patients enrolled in the EMPACT‐MI trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.2990)

Ioannou, A. et al. (2023) Conventional heart failure therapy in cardiac ATTR amyloidosis. European Heart Journal, 44, pp. 2893-2907. (doi: 10.1093/eurheartj/ehad347)

Yeoh, S. E., Osmanska, J., Petrie, M. C., Brooksbank, K. J.M., Clark, A. L., Docherty, K. F., Foley, P. W.X., Guha, K., Halliday, C. A., Jhund, P. S., Kalra, P. R., McKinley, G., Lang, N. N., Lee, M. M.Y., McConnachie, A., McDermott, J. J., Platz, E., Sartipy, P., Seed, A., Stanley, B., Weir, R. A.P., Welsh, P., McMurray, J. J.V., Campbell, R. T. (2023) Dapagliflozin versus metolazone in heart failure resistant to loop diuretics. European Heart Journal, 44, pp. 2966-2977. (doi: 10.1093/eurheartj/ehad341)

Mangion, K., Morrow, A. J., Sykes, R., Kamdar, A., Bagot, C., Bruce, G., Connelly, P., Delles, C., Gibson, V. B., Gillespie, L., Hall Barrientos, P., Lennie, V., Roditi, G., Sattar, N., Stobo, D., Allwood-Spiers, S., McConnachie, A., Berry, C., CISCO-19 investigators, (2023) Post-COVID-19 illness and associations with sex and gender. BMC Cardiovascular Disorders, 23, (doi: 10.1186/s12872-023-03412-7)

Docherty, K. F., Jackson, A. M., Macartney, M., Campbell, R. T., Petrie, M. C., Pfeffer, M. A., McMurray, J. J.V., Jhund, P. S. (2023) Declining risk of heart failure hospitalization following first acute myocardial infarction in Scotland between 1991–2016. European Journal of Heart Failure, 25, pp. 1213-1224. (doi: 10.1002/ejhf.2965)

Ofosu, E. F., de Nys, L., Connelly, J., Ryde, G. C., Whittaker, A. C. (2023) Dimensions of physical activity are important in managing anxiety in older adults: a systematic review and meta-analysis. Journal of Aging and Physical Activity, 31, pp. 679-692. (doi: 10.1123/japa.2022-0098)

Docherty, K. F., Lam, C. S.P., Rakisheva, A., Coats, A. J.S., Greenhalgh, T., Metra, M., Petrie, M. C., Rosano, G. M.C. (2023) Heart failure diagnosis in the general community - who, how and when? A clinical consensus statement of the Heart Failure Association (HFA) of the ESC. European Journal of Heart Failure, 25, pp. 1185-1198. (doi: 10.1002/ejhf.2946)

Brown, C. E., Casey, H., Dominiczak, A. F., Kerr, S., Campbell, A., Delles, C. (2023) Impact of preeclampsia on cardiovascular events: an analysis of the Generation Scotland: Scottish family health study. Journal of Human Hypertension, 37, pp. 735-741. (doi: 10.1038/s41371-023-00812-2)

Connelly, P. J., Delles, C. (2023) Journal of Human Hypertension special issue on sex and gender differences in hypertension. Journal of Human Hypertension, 37, pp. 587-588. (doi: 10.1038/s41371-023-00847-5)

Casey, H., Dennehy, N., Fraser, A., Lees, C., McEniery, C. M., Scott, K., Wilkinson, I. B., Delles, C. (2023) Placental syndromes and maternal cardiovascular health. Clinical Science, 137, pp. 1211-1224. (doi: 10.1042/CS20211130)

Olivera, S., Graham, D. (2023) Sex differences in preclinical models of hypertension. Journal of Human Hypertension, 37, pp. 619-625. (doi: 10.1038/s41371-022-00770-1)

Nadarajah, R., Younsi, T., Romer, E., Raveendra, K., Nakao, Y., Nakao, K., Shuweidhi, F., Hogg, D., Arbel, R., Zahger, D., Iakobishvili, Z., Fonarow, G. C., Petrie, M. C., Wu, J., Gale, C. P. (2023) Prediction models for heart failure in the community: a systematic review and meta‐analysis. European Journal of Heart Failure, (doi: 10.1002/ejhf.2970)

Kondo, T., Jering, K. S., Jhund, P. S., Anand, I. S., Desai, A. S., Lam, C. S.P., Maggioni, A. P., Martinez, F. A., Packer, M., Petrie, M. C., Pfeffer, M. A., Redfield, M. M., Rouleau, J. L., van Veldhuisen, D. J., Zannad, F., Zile, M. R., Solomon, S. D., McMurray, J. J.V. (2023) Predicting stroke in heart failure and preserved ejection fraction without atrial fibrillation. Circulation: Heart Failure, 16, (doi: 10.1161/CIRCHEARTFAILURE.122.010377)

Araki, T., Kondo, T., Imaizumi, T., Sumita, Y., Nakai, M., Tanaka, A., Okumura, T., Yang, M., Butt, J. H., Petrie, M. C., Murohara, T. (2023) Relationship between the volume of cases and in-hospital mortality in patients with cardiogenic shock receiving short-term mechanical circulatory support. American Heart Journal, 261, pp. 109-123. (doi: 10.1016/j.ahj.2023.03.017)

Curtain, J. P., Lee, M. M.Y., McMurray, J. J.V., Gardner, R. S., Petrie, M. C., Jhund, P. S. (2023) Efficacy of implantable haemodynamic monitoring in heart failure across ranges of ejection fraction: a systematic review and meta-analysis. Heart, 109, pp. 823-831. (doi: 10.1136/heartjnl-2022-321885)

De Beer, D., Mels, C. M.C., Schutte, A. E., Delles, C., Mary, S., Mullen, W., Latosinska, A., Mischak, H., Kruger, R. (2023) Identifying a urinary peptidomics profile for hypertension in young adults: the African-PREDICT study. Proteomics, 23, (doi: 10.1002/pmic.202200444)

Gard, E. K., Beale, A. L., Telles, F., Silvestry, F. E., Hanff, T., Hummel, S. L., Litwin, S. E., Petrie, M. C., Shah, S. J., Borlaug, B. A., Burkhoff, D., Komtebedde, J., Kaye, D. M., Nanayakkara, S. (2023) Left atrial enlargement is associated with pulmonary vascular disease in heart failure with preserved ejection fraction. European Journal of Heart Failure, 25, pp. 806-814. (doi: 10.1002/ejhf.2805)

Angelov, A., Connelly, P. J., Delles, C., Kararigas, G. (2023) Sex-biased and sex hormone-dependent regulation of apolipoprotein A1. Current Opinion in Physiology, 33, (doi: 10.1016/j.cophys.2023.100654)

Lam, C. S. P., Harding, E., Bains, M., Chin, A., Kanumilli, N., Petrie, M. C., Pohja-Hutchison, P., Yang, J., Butler, J. (2023) Identification of urgent gaps in public and policymaker knowledge of heart failure: results of a global survey. BMC Public Health, 23, (doi: 10.1186/s12889-023-15405-4)

Arisido, M. W., Foco, L., Shoemaker, R., Melotti, R., Delles, C., Gögele, M., Barolo, S., Baron, S., Azizi, M., Dominiczak, A. F., Zennaro, M.-C., P. Pramstaller, P., Poglitsch, M., Pattaro, C. (2023) Cluster analysis of angiotensin biomarkers to identify antihypertensive drug treatment in population studies. BMC Medical Research Methodology, 23, (doi: 10.1186/s12874-023-01930-8)

Wang, Y. et al. (2023) Early-life cardiovascular risk factor trajectories and vascular aging in midlife: a 30-year prospective cohort study. Hypertension, 80, pp. 1057-1066. (doi: 10.1161/HYPERTENSIONAHA.122.20518)

Dewan, P., Ferreira, J. P., Butt, J. H., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Køber, L., Packer, M., Rouleau, J. L., Stewart, S., Swedberg, K., Zile, M. R., Solomon, S. D., Jhund, P. S., McMurray, J. J.V. (2023) Impact of multimorbidity on mortality in HFrEF : which comorbidities matter most? – an analysis of PARADIGM‐HF and ATMOSPHERE. European Journal of Heart Failure, 25, pp. 687-697. (doi: 10.1002/ejhf.2856)

Girerd, N. et al. (2023) Protein biomarkers of new-onset heart failure: insights from the Heart Omics and Ageing cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circulation: Heart Failure, 16, pp. 426-441. (doi: 10.1161/CIRCHEARTFAILURE.122.009694)

Tromp, J., Jackson, A. M., Abdelhamid, M., Fouad, D., Youssef, G., Petrie, M. C., Bauersachs, J., Sliwa, K., van der Meer, P. (2023) Thrombo‐embolic events in peripartum cardiomyopathy: results from the ESC EORP PPCM registry. European Journal of Heart Failure, (doi: 10.1002/ejhf.2871)

Degenaar, A., Jacobs, A., Kruger, R., Delles, C., Mischak, H., Mels, C.M.C. (2023) Cardiovascular risk and kidney function profiling using conventional and novel biomarkers in young adults: the African-PREDICT study. BMC Nephrology, 24, (doi: 10.1186/s12882-023-03100-w)

Butler, J., Petrie, M. C., Bains, M., Bawtinheimer, T., Code, J., Levitch, T., Malvolti, E., Monteleone, P., Stevens, P., Vafeiadou, J., Lam, C. S. P. (2023) Challenges and opportunities for increasing patient involvement in heart failure self-care programs and self-care in the post–hospital discharge period. Research Involvement and Engagement, 9, (doi: 10.1186/s40900-023-00412-x)

Butt, J. H., Petrie, M. C., Jhund, P. S., Sattar, N., Desai, A. S., Køber, L., Rouleau, J. L., Swedberg, K., Zile, M. R., Solomon, S. D., Packer, M., McMurray, J. J.V. (2023) Anthropometric measures and adverse outcomes in heart failure with reduced ejection fraction: revisiting the obesity paradox. European Heart Journal, 44, pp. 1136-1153. (doi: 10.1093/eurheartj/ehad083)

Bruhn, J., Malmborg, M., Garred, C. H., Ravn, P., Zahir, D., Andersson, C., Gislason, G., Torp-Pedersen, C., Kragholm, K., Fosbol, E., Butt, J. H., Lang, N. N., Petrie, M. C., McMurray, J., Kober, L., Schou, M. (2023) Temporal trends in the incidence of malignancy in heart failure: a nationwide Danish study. European Heart Journal, 44, pp. 1124-1132. (doi: 10.1093/eurheartj/ehac797)

Mooney, L., Jackson, C. E., Adamson, C., McConnachie, A., Welsh, P., Myles, R. C., McMurray, J. J.V., Jhund, P. S., Petrie, M. C., Lang, N. N. (2023) Adverse outcomes associated with interleukin-6 in patients recently hospitalized for heart failure with preserved ejection fraction. Circulation: Heart Failure, 16, (doi: 10.1161/CIRCHEARTFAILURE.122.010051)

Desai, A. S., Petrie, M. C. (2023) Centrally adjudicated heart failure outcomes are needed in clinical trials. JACC: Heart Failure, 11, pp. 418-421. (doi: 10.1016/j.jchf.2023.01.028)

Dobbin, S. J.H., Shen, L., Petrie, M. C., Packer, M., Solomon, S. D., McMurray, J. J.V., Lang, N. N., Jhund, P. S. (2023) Characteristics and outcomes of patients with a history of cancer recruited to heart failure trials. European Journal of Heart Failure, 25, pp. 488-496. (doi: 10.1002/ejhf.2818)

De Nys, L., Ofosu, E. F., Ryde, G. C., Connelly, J., Whittaker, A. C. (2023) Physical activity influences cortisol and dehydroepiandrosterone (sulfate) levels in older adults: a systematic review and meta-analysis. Journal of Aging and Physical Activity, 31, pp. 330-351. (doi: 10.1123/japa.2021-0501)

Rotbain Curovic, V. et al. (2023) Presence of retinopathy and incident kidney and cardiovascular events in type 2 diabetes with normoalbuminuria – a post-hoc analysis of the PRIORITY randomized clinical trial. Journal of Diabetes and its Complications, 37, (doi: 10.1016/j.jdiacomp.2023.108433)

Edgar, B., Pearson, R., Kasthuri, R., Gillis, K., Geddes, C., Rostron, M., Brady, A., Hussey, K., Roditi, G., Delles, C., Kingsmore, D. (2023) The impact of renal artery stenting on therapeutic aims. Journal of Human Hypertension, 37, pp. 265-272. (doi: 10.1038/s41371-022-00785-8)

Whittaker, A., Tomaz, S. A., Bradwell, H., Ritchie, J., Edwards, K., Hennessy, C., Jones, R., Haynes, R., Ryde, G. C., Coffee, P. (2023) Intergenerational Co-production to Increase Physical and Social Activity For Health in the GOALD project (Generating Older Active Lives Digitally)

Ofosu, E.F., De Nys, L., Connelly, J., Ryde, G.C., Whittaker, A.C. (2023) A realist evaluation of the feasibility of a randomised controlled trial of a digital music and movement intervention for older people living in care homes. BMC Geriatrics, 23, (doi: 10.1186/s12877-023-03794-5)

Kimera, I. D., Namugenyi, C., Schwartz, J. I., Musimbaggo, D. J., Ssenyonjo, R., Atukunda, P., Mutungi, G., Mugabe, F., Ambangira, F., Mbuliro, M., Katwesigye, R., Neupane, D., Ssinabulya, I., Semitala, F. C., Delles, C., Muddu, M. (2023) Integrated multi-month dispensing of antihypertensive and antiretroviral therapy to sustain hypertension and HIV control. Journal of Human Hypertension, 37, pp. 213-219. (doi: 10.1038/s41371-022-00655-3)

Picone, D. S., Peterson, G. M., Jackson, S. L., Campbell, N. R.C., Delles, C., Olsen, M. H., Padwal, R., Schutte, A. E., Sharman, J. E. (2023) Perceptions of pharmacists on the quality of automated blood pressure devices: a national survey. Journal of Human Hypertension, 37, pp. 235-240. (doi: 10.1038/s41371-022-00670-4)

Curtain, J. P., Adamson, C., Kondo, T., Butt, J., Desai, A. S., Zannad, F., Rouleau, J. L., Rohde, L. E., Kober, L., Anand, I. S., van Veldhuisen, D. J., Zile, M. R., Lefkowitz, M. P., Solomon, S. D., Packer, M., Petrie, M. C., Jhund, P. S., McMurray, J. J.V. (2023) Investigator-reported ventricular arrhythmias and mortality in heart failure with mildly reduced or preserved ejection fraction. European Heart Journal, 44, pp. 668-677. (doi: 10.1093/eurheartj/ehac801)

Pathak, S., Lai, F. Y., Miksza, J., Petrie, M. C., Roman, M., Murray, S., Dearling, J., Perera, D., Murphy, G. J. (2023) Surgical or percutaneous coronary revascularization for heart failure: an in silico model using routinely collected health data to emulate a clinical trial. European Heart Journal, 44, pp. 351-364. (doi: 10.1093/eurheartj/ehac670)

de Beer, D., Mels, C. M. C., Schutte, A. E., Delles, C., Mary, S., Mullen, W., Mischak, H., Kruger, R. (2023) A urinary peptidomics approach for early stages of cardiovascular disease risk: the African-PREDICT study. Hypertension Research, 46, pp. 485-494. (doi: 10.1038/s41440-022-01097-7)

Lim, M. W.S., Setjiadi, D., Dobbin, S. J.H., Lang, N. N., Delles, C., Connelly, P. J. (2023) Nailfold video-capillaroscopy in the study of cardiovascular disease: a systematic review. Blood Pressure Monitoring, 28, pp. 24-32. (doi: 10.1097/MBP.0000000000000624)

Rushworth, L. K., Loveridge, C., Salji, M., MacLeod, M., Mui, E., Sumpton, D., Neilson, M., Hedley, A., Alexander, L., McCartney, E., Patel, R., Wallace, J., Delles, C., Jones, R., Leung, H. Y. (2023) Phase II proof of concept study of atorvastatin in castration resistant prostate cancer. BJU International, 131, pp. 236-243. (doi: 10.1111/bju.15851)

Kondo, T., Araki, T., Imaizumi, T., Sumita, Y., Nakai, M., Tanaka, A., Okumura, T., Butt, J. H., Petrie, M. C., McMurray, J. J.V., Murohara, T. (2023) Prognosis in patients with cardiogenic shock who received temporary mechanical circulatory support. JACC: Asia, 3, pp. 122-134. (doi: 10.1016/j.jacasi.2022.10.004)

Chen, J. Y., Chew, K. S., Mary, S., Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M., Delles, C., Rossitto, G. (2023) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137, pp. 239-250. (doi: 10.1042/CS20220609)

Sharman, J. E., Ordunez, P., Brady, T., Parati, G., Stergiou, G., Whelton, P. K., Padwal, R., Olsen, M. H., Delles, C., Schutte, A. E., Tomaszewski, M., Lackland, D. T., Khan, N., McManus, R. J., Tsuyuki, R. T., Zhang, X.-H., Murphy, L. D., Moran, A. E., Schlaich, M. P., Campbell, N. R.C. (2023) The urgency to regulate validation of automated blood pressure measuring devices: a policy statement and call to action from the world hypertension league. Journal of Human Hypertension, 37, pp. 155-159. (doi: 10.1038/s41371-022-00747-0)

Sattar, N., Deanfield, J., Delles, C. (2023) Impact of intentional weight loss in cardiometabolic disease: what we know about timing of benefits on differing outcomes? Cardiovascular Research, (doi: 10.1093/cvr/cvac186)

Niven, A., Ainge, J., Allison, M., Gorely, T., Kelly, P., Ozakinci, G., Ryde, G. C., Warne, S., Tomaz, S. A., Whiteford, V., Greenwood, C. (2023) Building partnerships: a case study of physical activity researchers and practitioners collaborating to build evidence to inform the delivery of a workplace step count challenge. Frontiers in Sports and Active Living, 4, (doi: 10.3389/fspor.2022.1067127)

Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10, (doi: 10.1136/openhrt-2022-002192)

Petrie, M. C., Jhund, P. S., Connolly, E., Mark, P. B., MacDonald, M. R., Robertson, M., Anker, S. D., Bhandari, S., Farrington, K., Kalra, P. A., Wheeler, D. C., Tomson, C. R.V., Ford, I., McMurray, J. J.V., Macdougall, I. C. (2023) High-dose intravenous iron reduces myocardial infarction in patients on haemodialysis. Cardiovascular Research, 119, pp. 213-220. (doi: 10.1093/cvr/cvab317)

Kulkarni, S., Glover, M., Kapil, V., Abrams, S. M. L., Partridge, S., McCormack, T., Sever, P., Delles, C., Wilkinson, I. B. (2023) Management of hypertensive crisis: British and Irish Hypertension Society position document. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00776-9)

Perera, D., Ryan, M., Morgan, H. P., Greenwood, J. P., Petrie, M. C., Dodd, M., Weerackody, R., O'Kane, P. D., Masci, P. G., Nazir, M. S., Papachristidis, A., Chahal, N., Khattar, R., Ezad, S. M., Kapetanakis, S., Dixon, L. J., De Silva, K., McDiarmid, A. K., Marber, M. S., McDonagh, T., McCann, G. P., Clayton, T. C., Senior, R., Chiribiri, A. (2023) Viability and outcomes with revascularization or medical therapy in ischemic ventricular dysfunction: a prespecified secondary analysis of the REVIVED-BCIS2 Trial. JAMA Cardiology, 8, pp. 1154-1161. (doi: 10.1001/jamacardio.2023.3803)

Alkhubaizi, A. A., Ryde, G. C., Tomaz, S. A., Whittaker, A. C. (2023) Workplace physical activity within the Gulf Cooperation Council region: a scoping review. Physical Activity and Health, 7, pp. 191-204. (doi: 10.5334/paah.280)

2022

Kalra, P. R., Cleland, J. G.F., Petrie, M. C., Thomson, E. A., Kalra, P. A., Squire, I. B., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Foley, P. W.X., Graham, F. J., Japp, A. G., Lane, R. E., Lang, N. N., Ludman, A. J., Macdougall, I. C., Pellicori, P., Ray, R., Robertson, M., Seed, A., Ford, I. (2022) Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial. Lancet, 400, pp. 2199-2209. (doi: 10.1016/S0140-6736(22)02083-9)

Murray, E. C., Delles, C., Orzechowski, P., Renc, P., Sitek, A., Wagenaar, J., Guzik, T. J. (2022) Vascular phenotypes in early hypertension. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00794-7)

Mehran, R., Steg, P. G., Pfeffer, M. A., Jering, K., Claggett, B., Lewis, E. F., Granger, C., Køber, L., Maggioni, A., Mann, D. L., McMurray, J. J.V., Rouleau, J.-L., Solomon, S. D., Ducrocq, G., Berwanger, O., De Pasquale, C. G., Landmesser, U., Petrie, M., Leng, D. S. K., van der Meer, P., Lefkowitz, M., Zhou, Y., Braunwald, E. (2022) The effects of angiotensin receptor-neprilysin inhibition on major coronary events in patients with acute myocardial infarction: insights from the PARADISE-MI trial. Circulation, 146, pp. 1749-1757. (doi: 10.1161/CIRCULATIONAHA.122.060841)

Gregers, M. C. T., Schou, M., Jensen, M. T., Jensen, J., Petrie, M. C., Vilsbøll, T., Goetze, J. P., Rossing, P., Jørgensen, P. G. (2022) Diagnostic and prognostic value of the electrocardiogram in stable outpatients with type 2 diabetes. Scandinavian Cardiovascular Journal, 56, pp. 256-263. (doi: 10.1080/14017431.2022.2095435)

Mark, P. B., Mangion, K., Rankin, A. J., Rutherford, E., Lang, N. N., Petrie, M. C., Stoumpos, S., Patel, R. K. (2022) Left ventricular dysfunction with preserved ejection fraction: the most common left ventricular disorder in chronic kidney disease patients. Clinical Kidney Journal, 15, pp. 2186-2199. (doi: 10.1093/ckj/sfac146)

Rossitto, G., Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289, pp. 7260-7273. (doi: 10.1111/febs.16155)

Kalra, P. R., Cleland, J. G. F., Petrie, M. C., Ahmed, F. Z., Foley, P. W. X., Kalra, P. A., Lang, N. N., Lane, R. E., Macdougall, I. C., Pellicori, P., Pope, M. T. B., Robertson, M., Squire, I. B., Thomson, E. A., Ford, I. (2022) Rationale and design of a randomised trial of intravenous iron in patients with heart failure. Heart, 108, pp. 1979-1985. (doi: 10.1136/heartjnl-2022-321304)

Kumar, A. A., Yeo, N., Whittaker, M., Attra, P., Barrick, T. R., Bridges, L. R., Dickson, D. W., Esiri, M. M., Farris, C. W., Graham, D., Lin, W. L., Meijles, D. N., Pereira, A. C., Perry, G., Rosene, D. L., Shtaya, A. B., Van Agtmael, T., Zamboni, G., Hainsworth, A. H. (2022) Vascular collagen type-IV in hypertension and cerebral small vessel disease. Stroke, 53, pp. 3696-3705. (doi: 10.1161/STROKEAHA.122.037761)

Tromp, J., Bauer, D., Claggett, B. L., Frost, M., Iversen, M. B., Prasad, N., Petrie, M. C., Larson, M. G., Ezekowitz, J. A., Solomon, S. D. (2022) A formal validation of a deep learning-based automated workflow for the interpretation of the echocardiogram. Nature Communications, 13, (doi: 10.1038/s41467-022-34245-1)

Kondo, T., Abdul-Rahim, A. H., Talebi, A., Abraham, W. T., Desai, A. S., Dickstein, K., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Packer, M., Petrie, M., Ponikowski, P., Rouleau, J. L., Sabatine, M. S., Swedberg, K., Zile, M. R., Solomon, S. D., Jhund, P. S., McMurray, J. J.V. (2022) Predicting stroke in heart failure and reduced ejection fraction without atrial fibrillation. European Heart Journal, 43, pp. 4469-4479. (doi: 10.1093/eurheartj/ehac487)

Bell, L., Ryde, G. (2022) Walking and writing, running and redrafting: towards a template for the physically-active creative. Writing in Practice, 8, pp. 100-111.

Harrington, J., Udell, J. A., Jones, W. S., Anker, S. D., Bhatt, D. L., Petrie, M. C., Vedin, O., Sumin, M., Zwiener, I., Hernandez, A. F., Butler, J. (2022) Empagliflozin in patients post myocardial infarction rationale and design of the EMPACT-MI trial. American Heart Journal, 253, pp. 86-98. (doi: 10.1016/j.ahj.2022.05.010)

Arulmurugananthavadivel, A., Holt, A., Parveen, S., Lamberts, M., Gislason, G. H., Torp-Pedersen, C., Madelaire, C., Andersson, C., Zahir, D., Butt, J. H., Petrie, M. C., McMurray, J., Fosbol, E. L., Kober, L., Schou, M. (2022) Importance of diagnostic setting in determining mortality in patients with new-onset heart failure: temporal trends in Denmark 1997–2017. European Heart Journal: Quality of Care and Clinical Outcomes, 8, pp. 750-760. (doi: 10.1093/ehjqcco/qcab073)

Mary, S., Boder, P., Padmanabhan, S., McBride, M. W., Graham, D., Delles, C., Dominiczak, A. F. (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888)

Seckin, M., Johnston, B., Petrie, M. C., Stewart, S., Chan, Y.-K. (2022) Characteristics of symptoms and symptom change across different heart failure subtypes: a sex-stratified analysis. European Journal of Cardiovascular Nursing, (doi: 10.1093/eurjcn/zvac099)

Garred, C. H., Zahir, D., Butt, J. H., Ravn, P. B., Bruhn, J., Gislason, G. H., Fosbøl, E. L., Torp‐Pedersen, C., Petrie, M. C., McMurray, J. J.V., Køber, L., Schou, M. (2022) Adherence and discontinuation of optimal heart failure therapies according to age: a Danish nationwide study. Journal of the American Heart Association, 11, (doi: 10.1161/JAHA.122.026187)

Desai, A. S., Jhund, P. S., Claggett, B. L., Vaduganathan, M., Miao, Z. M., Kondo, T., Barkoudah, E., Brahimi, A., Connolly, E., Finn, P., Lang, N. N., Mc Causland, F. R., McGrath, M., Petrie, M. C., McMurray, J. J.V., Solomon, S. D. (2022) Effect of dapagliflozin on cause-specific mortality in patients with heart failure across the spectrum of ejection fraction. JAMA Cardiology, 7, pp. 1227-1234. (doi: 10.1001/jamacardio.2022.3736)

Harrington, J., Petrie, M. C., Anker, S. D., Bhatt, D. L., Jones, S. W., Udell, J. A., Hernandez, A. F., Butler, J. (2022) Evaluating the application of chronic heart failure therapies and developing treatments in individuals with recent myocardial infarction. JAMA Cardiology, 7, pp. 1067-1075. (doi: 10.1001/jamacardio.2022.2847)

Mary, S., Rossitto, G., Delles, C. (2022) Pathophysiology of hypertension. Oxford University Press

Welsh, P., Campbell, R. T., Mooney, L., Kimenai, D. M., Hayward, C., Campbell, A., Porteous, D., Mills, N., Lang, N. N., Petrie, M. C., Januzzi, J. L., McMurray, J. J.V., Sattar, N. (2022) Reference ranges for NT-proBNP (N-terminal pro-B-type natriuretic peptide) and risk factors for higher NT-proBNP concentrations in a large general population cohort. Circulation: Heart Failure, 15, pp. 957-967. (doi: 10.1161/CIRCHEARTFAILURE.121.009427)

Gao, X., Kuo, C.-W., Main, A., Brown, E., Rios, F. J., De Lucca Camargo, L., Mary, S., Wypijewski, K., Gök, C., Touyz, R. M., Fuller, W. (2022) Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7. Cell Calcium, 106, (doi: 10.1016/j.ceca.2022.102639)

De Nys, L., Anderson, K., Ofosu, E. F., Ryde, G. C., Connelly, J., Whittaker, A. C. (2022) The effects of physical activity on cortisol and sleep: A systematic review and meta-analysis. Psychoneuroendocrinology, 143, (doi: 10.1016/j.psyneuen.2022.105843)

Adamson, C., Docherty, K. F., Heerspink, H. J.L., de Boer, R. A., Damman, K., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Petrie, M. C., Ponikowski, P., Sabatine, M. S., Schou, M., Solomon, S. D., Verma, S., Bengtsson, O., Langkilde, A. M., Sjöstrand, M., Vaduganathan, M., Jhund, P. S., McMurray, J. J.V. (2022) Initial decline ("dip") in estimated glomerular filtration rate following initiation of dapagliflozin in patients with heart failure and reduced ejection fraction: insights from DAPA-HF. Circulation, 146, pp. 438-449. (doi: 10.1161/CIRCULATIONAHA.121.058910)

Hoes, M. F., Arany, Z., Bauersachs, J., Hilfiker-Kleiner, D., Petrie, M. C., Sliwa, K., van der Meer, P. (2022) Pathophysiology and risk factors of peripartum cardiomyopathy. Nature Reviews Cardiology, 19, pp. 555-565. (doi: 10.1038/s41569-021-00664-8)

Ryan, M., Perera, D., Petrie, M. C. (2022) Revascularisation and HFpEF – time for randomised trials. European Journal of Heart Failure, 24, pp. 1439-1440. (doi: 10.1002/ejhf.2583)

Lee, M. M.Y. et al. (2022) Effect of empagliflozin on kidney biochemical and imaging outcomes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 146, pp. 364-367. (doi: 10.1161/CIRCULATIONAHA.122.059851)

Shen, L., Jhund, P. S., Docherty, K. F., Vaduganathan, M., Petrie, M. C., Desai, A. S., Køber, L., Schou, M., Packer, M., Solomon, S. D., Zhang, X., McMurray, J. J. V. (2022) Accelerated and personalized therapy for heart failure with reduced ejection fraction. European Heart Journal, 43, pp. 2573-2587. (doi: 10.1093/eurheartj/ehac210)

Tomaz, S. A., Ryde, G. C., Swales, B., Neely, K. C., Andreis, F., Coffee, P., Connelly, J., Kirkland, A., McCabe, L., Watchman, K., Martin, J. G., Pina, I., Whittaker, A. C. (2022) “… Exercise opportunities became very important”: Scottish older adults’ changes in physical activity during Covid19’ European Review of Aging and Physical Activity, 19, (doi: 10.1186/s11556-022-00295-z)

Lip, S., McCallum, L., Delles, C., McClure, J. D., Guzik, T., Berry, C., Touyz, R., Padmanabhan, S. (2022) Rationale and design for the LOnger-term effects of SARS-CoV-2 INfection on blood Vessels And blood pRessure (LOCHINVAR) Open Heart, 9, (doi: 10.1136/openhrt-2022-002057)

Swales, B., Ryde, G. C., Whittaker, A. C. (2022) A randomized controlled feasibility trial evaluating a resistance training intervention with frail older adults in residential care: The Keeping Active in Residential Elderly Trial. Journal of Aging and Physical Activity, 30, pp. 364-388. (doi: 10.1123/japa.2021-0130)

Craig, A., Delles, C., Murray, E. C. (2022) A review of vascular traits and assessment techniques, and their heritability. Artery Research, 28, pp. 61-78. (doi: 10.1007/s44200-022-00016-y)

Jackson, A. M., Benson, L., Savarese, G., Hage, C., Jhund, P. S., Petrie, M. C., Dahlström, U., McMurray, J. J.V., Lund, L. H. (2022) Apparent treatment-resistant hypertension across the spectrum of heart failure phenotypes in the Swedish HF Registry. JACC: Heart Failure, 10, pp. 380-392. (doi: 10.1016/j.jchf.2022.04.006)

Wang, Y. et al. (2022) Associations of long-term visit-to-visit blood pressure variability with subclinical kidney damage and albuminuria in adulthood: a 30-year prospective cohort study. Hypertension, 79, pp. 1247-1256. (doi: 10.1161/HYPERTENSIONAHA.121.18658)

Lucas-Herald, A. K., Delles, C. (2022) Carotid intima-media thickness is associated with obesity and hypertension in young people. Hypertension, 79, pp. 1177-1179. (doi: 10.1161/hypertensionaha.122.19163)

Curtain, J. P., Campbell, R. T., Petrie, M. C., Jackson, A. M., Abraham, W. T., Desai, A. S., Dickstein, K., Køber, L., Rouleau, J. L., Swedberg, K., Zile, M. R., Solomon, S. D., Jhund, P. S., McMurray, J. J.V. (2022) Clinical outcomes related to background diuretic use and new diuretic initiation in patients with HFrEF. JACC: Heart Failure, 10, pp. 415-427. (doi: 10.1016/j.jchf.2022.01.020)

Rastogi, T., Ho, F. K., Rossignol, P., Merkling, T., Butler, J., Clark, A., Collier, T., Delles, C., Jukema, J. W., Heymans, S., Latini, R., Mebazaa, A., Pellicori, P., Sever, P., Staessen, J. A., Thijs, L., Cleland, J. G., Sattar, N., Zannad, F., Girerd, N. (2022) Comparing and contrasting risk factors for heart failure in patients with and without history of myocardial infarction: data from HOMAGE and the UK Biobank. European Journal of Heart Failure, 24, pp. 976-984. (doi: 10.1002/ejhf.2495)

Connelly, P. J., Currie, G., Delles, C. (2022) Sex differences in the prevalence, outcomes and management of hypertension. Current Hypertension Reports, 24, pp. 185-192. (doi: 10.1007/s11906-022-01183-8)

Borlaug, B. A. et al. (2022) Latent pulmonary vascular disease may alter the response to therapeutic atrial shunt device in heart failure. Circulation, 145, pp. 1592-1604. (doi: 10.1161/CIRCULATIONAHA.122.059486)

Udell, J. A., Jones, W. S., Petrie, M. C., Harrington, J., Anker, S. D., Bhatt, D. L., Hernandez, A. F., Butler, J. (2022) Sodium glucose cotransporter-2 inhibition for acute myocardial infarction: JACC Review Topic of the Week. Journal of the American College of Cardiology, 79, pp. 2058-2068. (doi: 10.1016/j.jacc.2022.03.353)

Lucas-Herald, A. K., Montezano, A. C., Alves-Lopes, R., Haddow, L., Alimussina, M., O’Toole, S., Flett, M., Lee, B., Amjad, S. B., Steven, M., Brooksbank, K., McCallum, L., Delles, C., Padmanabhan, S., Ahmed, S. F., Touyz, R. M. (2022) Vascular dysfunction and increased cardiovascular risk in hypospadias. European Heart Journal, 43, pp. 1832-1845. (doi: 10.1093/eurheartj/ehac112)

Cohen, D. J., Wang, K., Magnuson, E. A., Smith, R. D., Petrie, M. C., Buch, M. H., Abraham, W. T., Lindenfeld, J., Mack, M. J., Stone, G. W., Cleland, J. G. F. (2022) Cost-effectiveness of transcatheter edge-to-edge repair in secondary mitral regurgitation. Heart, 108, pp. 717-724. (doi: 10.1136/heartjnl-2021-320005)

Rossitto, G., Delles, C. (2022) Does excess tissue sodium storage regulate blood pressure? Current Hypertension Reports, 24, pp. 115-122. (doi: 10.1007/s11906-022-01180-x)

Beazer, J. D., Freeman, D. J. (2022) Estradiol and HDL function in women – a partnership for life. Journal of Clinical Endocrinology and Metabolism, 107, pp. e2192-2194. (doi: 10.1210/clinem/dgab811)

He, W. et al. (2022) Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size. Cardiovascular Research, 118, pp. 1535-1547. (doi: 10.1093/cvr/cvab204)

Yeoh, S. E., Docherty, K. F., Jhund, P. S., Petrie, M. C., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Bengtsson, O., Boulton, D. W., Greasley, P. J., Langkilde, A. M., Sjöstrand, M., Solomon, S. D., McMurray, J. J.V. (2022) Relationship of dapagliflozin with serum sodium: findings from the DAPA-HF trial. JACC: Heart Failure, 10, pp. 306-318. (doi: 10.1016/j.jchf.2022.01.019)

Maurovich-Horvat, P. et al. (2022) CT or invasive coronary angiography in stable chest pain. New England Journal of Medicine, 386, pp. 1591-1602. (doi: 10.1056/NEJMoa2200963)

Sani, R. N., Connelly, P. J., Toft, M., Rowa-Dewar, N., Delles, C., Gasevic, D., Karaye, K. M. (2022) Rural-urban difference in the prevalence of hypertension in West Africa: a systematic review and meta-analysis. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00688-8)

Cotton, S. et al. (2022) Use of the oral beta blocker bisoprolol to reduce the rate of exacerbation in people with chronic obstructive pulmonary disease (COPD): a randomised controlled trial (BICS) Trials, 23, (doi: 10.1186/s13063-022-06226-8)

Toloza, F. J. K. et al. (2022) Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. Lancet Diabetes and Endocrinology, 10, pp. 243-252. (doi: 10.1016/S2213-8587(22)00007-9)

Butt, J. H., Docherty, K. F., Jhund, P. S., De Boer, R. A., Böhm, M., Desai, A. S., Howlett, J. G., Inzucchi, S. E., Kosiborod, M. N., Martinez, F. A., Nicolau, J. C., Petrie, M. C., Ponikowski, P., Bengtsson, O., Langkilde, A. M., Schou, M., Sjöstrand, M., Solomon, S. D., Sabatine, M. S., McMurray, J. J.V., Køber, L. (2022) Dapagliflozin and atrial fibrillation in heart failure with reduced ejection fraction: insights from DAPA-HF. European Journal of Heart Failure, 24, pp. 513-525. (doi: 10.1002/ejhf.2381)

Jackson, A. M. et al. (2022) Diabetes and pre‐diabetes in patients with heart failure and preserved ejection fraction. European Journal of Heart Failure, 24, pp. 497-509. (doi: 10.1002/ejhf.2403)

Curtain, J. P., Jackson, A., Shen, L., Jhund, P. S., Docherty, K. F., Petrie, M. C., Castagno, D., Desai, A. S., Rohde, L. E., Lefkowitz, M. P., Rouleau, J.-L., Zile, M. R., Solomon, S. D., Swedberg, K., Packer, M., McMurray, J. J.V. (2022) Effect of sacubitril/valsartan on investigator-reported ventricular arrhythmias in PARADIGM-HF. European Journal of Heart Failure, 24, pp. 551-561. (doi: 10.1002/ejhf.2419)

Glen, C., Tan, Y. Y., Waterston, A., Evans, T. R. J., Jones, R. J., Petrie, M. C., Lang, N. N. (2022) Mechanistic and clinical overview cardiovascular toxicity of BRAF and MEK inhibitors: JACC: CardioOncology state-of-the-art review. JACC: CardioOncology, 4, pp. 1-18. (doi: 10.1016/j.jaccao.2022.01.096)

Lee, M. M.Y., Docherty, K. F., Sattar, N., Mehta, N., Kalra, A., Nowacki, A. S., Solomon, S. D., Vaduganathan, M., Petrie, M. C., Jhund, P. S., McMurray, J. J.V. (2022) Renin–angiotensin system blockers, risk of SARS-CoV-2 infection and outcomes from CoViD-19: systematic review and meta-analysis. European Heart Journal: Cardiovascular Pharmacotherapy, 8, pp. 165-178. (doi: 10.1093/ehjcvp/pvaa138)

Mujaj, B., ZHang, Z.-Y., Yang, W.-Y., Thijs, L., Wei, F.-F., Verhamme, P., Delles, C., Butler, J., Sever, P., Latini, R., Cleland, J. G. F., Zannad, F., Staessen, J. A. (2022) Aspirin use is associated with increased risk for incident heart failure: a patient-level pooled analysis. ESC Heart Failure, 9, pp. 685-694. (doi: 10.1002/ehf2.13688)

Ryde, G. C., Tomaz, S. A., Sandison, K., Greenwood, C., Kelly, P. (2022) Measuring productivity, perceived stress and work engagement of a nationally delivered workplace step count challenge. International Journal of Environmental Research and Public Health, 19, (doi: 10.3390/ijerph19031843)

Deis, T., Wolsk, E., Mujkanovic, J., Komtebedde, J., Burkhoff, D., Kaye, D., Hasenfuß, G., Hayward, C., Van der Heyden, J., Petrie, M.C., Shah, S.J., Borlaug, B.A., Kahwash, R., Litwin, S., Hoendermis, E., Hummel, S., Gustafsson, F. (2022) Resting and exercise haemodynamic characteristics of patients with advanced heart failure and preserved ejection fraction. ESC Heart Failure, 9, pp. 186-195. (doi: 10.1002/ehf2.13697)

Connelly, P. J., Casey, H., Montezano, A. C., Touyz, R. M., Delles, C. (2022) Sex steroids receptors, hypertension and vascular ageing. Journal of Human Hypertension, 36, pp. 120-125. (doi: 10.1038/s41371-021-00576-7)

Docherty, K. F., Petrie, M. C. (2022) Sodium-glucose cotransporter 2 inhibitors as a treatment for heart failure. Heart, 108, pp. 312-320. (doi: 10.1136/heartjnl-2020-318658)

Januzzi, J. L., Garasic, J. M., Kasner, S. E., McDonald, V., Petrie, M. C., Seltzer, J., Mauro, M., Croce, K., Berman, E., Deininger, M., Hochhaus, A., Pinilla-Ibarz, J., Nicolini, F., Kim, D.-W., DeAngelo, D. J., Kantarjian, H., Xu, J., Hall, T., Srivastava, S., Naranjo, D., Cortes, J. (2022) Retrospective analysis of arterial occlusive events in the PACE trial by an independent adjudication committee. Journal of Hematology and Oncology, 15, (doi: 10.1186/s13045-021-01221-z)

Pfeffer, M. A. et al. (2022) Impact of sacubitril/valsartan versus ramipril on total heart failure events in the PARADISE-MI trial. Circulation, 145, pp. 87-89. (doi: 10.1161/CIRCULATIONAHA.121.057429)

Delles, C. (2022) Maternally inherited essential hypertension: adding further complexity to an already complex condition. American Journal of Hypertension, 35, pp. 16-18. (doi: 10.1093/ajh/hpab133)

Chan, Y., Seckin, M., Johnston, B., Petrie, M., Stewart, S. (2022) Characteristics of symptom change in men and women with different heart failure subtypes. Heart, Lung and Circulation, 31, (doi: 10.1016/j.hlc.2022.06.074)

Delles, C., Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water. Function, 3, (doi: 10.1093/function/zqab071)

2021

Connelly, P. J., Delles, C. (2021) Cardiovascular disease in transgender people: recent research and emerging evidence. Cardiovascular Research, 117, pp. e174-e176. (doi: 10.1093/cvr/cvab288)

Trivett, C., Lees, Z. J., Freeman, D. J. (2021) Adipose tissue function in healthy pregnancy, gestational diabetes mellitus and pre-eclampsia. European Journal of Clinical Nutrition, 75, pp. 1745-1756. (doi: 10.1038/s41430-021-00948-9)

Butt, J. H., Adamson, C., Docherty, K. F., de Boer, R. A., Petrie, M. C., Inzucchi, S. E., Kosiborod, M. N., Maria Langkilde, A., Lindholm, D., Martinez, F. A., Bengtsson, O., Schou, M., O’Meara, E., Ponikowski, P., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., Jhund, P. S., McMurray, J. J.V., Køber, L. (2021) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to N-terminal pro-B-type natriuretic peptide: insights from the DAPA-HF trial. Circulation: Heart Failure, 14, (doi: 10.1161/CIRCHEARTFAILURE.121.008837)

Diamant, M. J., Andrade, J. G., Virani, S. A., Jhund, P. S., Petrie, M. C., Hawkins, N. M. (2021) Heart failure and atrial flutter: a systematic review of current knowledge and practices. ESC Heart Failure, 8, pp. 4484-4496. (doi: 10.1002/ehf2.13526)

Jackson, A. M. et al. (2021) Hypertensive disorders in women with peripartum cardiomyopathy: insights from the ESC EORP PPCM Registry. European Journal of Heart Failure, 23, pp. 2058-2069. (doi: 10.1002/ejhf.2264)

Mary, S., Boder, P., Rossitto, G., Graham, L., Scott, K., Flynn, A., Kipgen, D., Graham, D., Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135, pp. 2749-2761. (doi: 10.1042/CS20211017)

Mark, P. B., Jhund, P. S., Walters, M. R., Petrie, M. C., Power, A., White, C., Robertson, M., Connolly, E., Anker, S. D., Bhandari, S., Farrington, K., Kalra, P. A., Tomson, C. R.V., Wheeler, D. C., Winearls, C. G., McMurray, J. J.V., Macdougall, I. C., Ford, I. (2021) Stroke in hemodialysis patients randomized to different intravenous iron strategies: a prespecified analysis from the PIVOTAL trial. Kidney360, 2, pp. 1761-1769. (doi: 10.34067/KID.0004272021)

van Vliet, N. A. et al. (2021) Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. BMC Medicine, 19, (doi: 10.1186/s12916-021-02130-1)

He, T. et al. (2021) Urinary peptides in heart failure: a link to molecular pathophysiology. European Journal of Heart Failure, 23, pp. 1875-1887. (doi: 10.1002/ejhf.2195)

Touyz, R. M., Boyd, M. O.E., Guzik, T., Padmanabhan, S., McCallum, L., Delles, C., Mark, P. B., Petrie, J. R., Rios, F., Montezano, A. C., Sykes, R., Berry, C. (2021) Cardiovascular and renal risk factors and complications associated with COVID-19. CJC Open, 3, pp. 1257-1272. (doi: 10.1016/j.cjco.2021.05.020)

Adamson, C., Jhund, P. S., Docherty, K. F., Bělohlávek, J., Chiang, C.‐E., Diez, M., Drożdż, J., Dukát, A., Howlett, J., Ljungman, C. E.A., Petrie, M. C., Schou, M., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Bengtsson, O., Langkilde, A. M., Lindholm, D., Sjöstrand, M., McMurray, J. J.V. (2021) Efficacy of dapagliflozin in heart failure with reduced ejection fraction according to body mass index. European Journal of Heart Failure, 23, pp. 1662-1672. (doi: 10.1002/ejhf.2308)

Raafs, A. et al. (2021) Identification of sex‐specific biomarkers predicting new‐onset heart failure. ESC Heart Failure, 8, pp. 3512-3520. (doi: 10.1002/ehf2.13476)

Rush, C. J., Berry, C., Oldroyd, K. G., Rocchiccioli, J. P., Lindsay, M. M., Touyz, R. M., Murphy, C. L., Ford, T. J., Sidik, N., McEntegart, M. B., Lang, N. N., Jhund, P. S., Campbell, R. T., McMurray, J. J.V., Petrie, M. C. (2021) Prevalence of coronary artery disease and coronary microvascular dysfunction in patients with heart failure with preserved ejection fraction. JAMA Cardiology, 6, pp. 1130-1143. (doi: 10.1001/jamacardio.2021.1825)

Curtain, J. P., Docherty, K. F., Jhund, P. S., Petrie, M. C., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F., Ponikowski, P., Sabatine, M. S., Bengtsson, O., Langkilde, A. M., Sjöstrand, M., Solomon, S. D., McMurray, J. J.V. (2021) Effect of dapagliflozin on ventricular arrhythmias, resuscitated cardiac arrest, or sudden death in DAPA-HF. European Heart Journal, 42, pp. 3727-3738. (doi: 10.1093/eurheartj/ehab560)

Docherty, N. G., Delles, C., D’Haese, P., Layton, A. T., Martínez-Salgado, C., Vervaet, B. A., López-Hernández, F. J. (2021) Haemodynamic frailty – A risk factor for acute kidney injury in the elderly. Ageing Research Reviews, 70, (doi: 10.1016/j.arr.2021.101408)

Alves-Lopes, R., Montezano, A. C., Neves, K. B., Harvey, A., Rios, F. J., Skiba, D. S., Arendse, L. B., Guzik, T. J., Graham, D., Poglitsch, M., Sturrock, E., Touyz, R. M. (2021) Selective inhibition of the C-domain of ACE (angiotensin-converting enzyme) combined with inhibition of NEP (neprilysin): a potential new therapy for hypertension. Hypertension, 78, pp. 604-616. (doi: 10.1161/HYPERTENSIONAHA.121.17041)

Rørth, R., Clausen, M. F., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2021) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure, stroke, chronic obstructive pulmonary disease or cancer. PLoS ONE, 16, (doi: 10.1371/journal.pone.0255364)

Boder, P., Mary, S., Mark, P. B., Leiper, J., Dominiczak, A. F., Padmanabhan, S., Rampold, L., Delles, C. (2021) Mechanistic interactions of uromodulin with the thick ascending limb: perspectives in physiology and hypertension. Journal of Hypertension, 39, pp. 1490-1504. (doi: 10.1097/HJH.0000000000002861)

Graham, F. J., Pellicori, P., Ford, I., Petrie, M. C., Kalra, P. R., Cleland, J. G.F. (2021) Intravenous iron for heart failure with evidence of iron deficiency: a meta-analysis of randomised trials. Clinical Research in Cardiology, 110, pp. 1299-1307. (doi: 10.1007/s00392-021-01837-8)

Petrie, M. C., Lee, M. M.Y., Docherty, K. F. (2021) Sodium–glucose co-transporter 2 inhibitors—the first successful treatment for heart failure with preserved ejection fraction? European Journal of Heart Failure, 23, pp. 1256-1259. (doi: 10.1002/ejhf.2108)

Patanapirunhakit, P., Karlsson, H., Mulder, M., Ljunggren, S., Graham, D., Freeman, D. (2021) Sphingolipids in HDL – potential markers for adaptation to pregnancy? Biochimica et Biophysica Acta: Molecular and Cell Biology of Lipids, 1866, (doi: 10.1016/j.bbalip.2021.158955)

Lee, M. M.Y., McMurray, J. J.V., Jhund, P. S., Petrie, M. C., Sattar, N. (2021) Response by Lee et al to letter regarding article, "Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)" Circulation, 144, pp. e40. (doi: 10.1161/CIRCULATIONAHA.121.055067)

Docherty, K. F., Campbell, R. T., Brooksbank, K. J.M., Dreisbach, J. G., Forsyth, P., Godeseth, R., Hopkins, T., Jackson, A. M., Lee, M. M.Y., McConnachie, A., Roditi, G., Squire, I. B., Stanley, B., Welsh, P., Jhund, P. S., Petrie, M., McMurray, J. J.V. (2021) The effect of neprilysin inhibition on left ventricular remodeling in patients with asymptomatic left ventricular systolic dysfunction late after myocardial infarction. Circulation, 144, pp. 199-209. (doi: 10.1161/CIRCULATIONAHA.121.054892)

Simpson, J., Jackson, C. E., Haig, C., Jhund, P. S., Tomaszewski, M., Gardner, R. S., Tsorlalis, Y., Petrie, M. C., McMurray, J. J.V., Squire, I. B., Gupta, P. (2021) Adherence to prescribed medications in patients with heart failure – insights from liquid chromatography-tandem mass spectrometry-based urine analysis. European Heart Journal: Cardiovascular Pharmacotherapy, 7, pp. 296-301. (doi: 10.1093/ehjcvp/pvaa071)

Jhund, P. S., Petrie, M. C., Robertson, M., Mark, P. B., MacDonald, M. R., Connolly, E., Anker, S. D., Bhandari, S., Farrington, K., Kalra, P. A., Wheeler, D. C., Tomson, C. R.V., Ford, I., McMurray, J. J.V., Macdougall, I. C. (2021) Heart failure hospitalization in adults receiving maintenance hemodialysis and effect of intravenous iron therapy: A report from PIVOTAL. JACC: Heart Failure, 9, pp. 518-527. (doi: 10.1016/j.jchf.2021.04.005)

Butt, J. H., Docherty, K. F., Petrie, M. C., Schou, M., Kosiborod, M. N., O’Meara, E., Katova, T., Ljungman, C. E.A., Diez, M., Ogunniyi, M. O., Langkilde, A. M., Sjöstrand, M., Lindholm, D., Bengtsson, O., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Jhund, P. S., McMurray, J. J.V., Køber, L. (2021) Efficacy and safety of dapagliflozin in men and women with heart failure with reduced ejection fraction: results from the DAPA-HF trial. JAMA Cardiology, 6, pp. 678-689. (doi: 10.1001/jamacardio.2021.0379)

Murray, E., Rossitto, G., Delles, C. (2021) Haemodynamic assessment in hypertension: the soloists and the orchestra. Journal of Hypertension, 39, pp. 1109-1111. (doi: 10.1097/HJH.0000000000002796)

Mary, S., Small, H., Herse, F., Carrick, E., Flynn, A., Mullen, W., Dechend, R., Delles, C. (2021) Pre-existing hypertension and pregnancy induced hypertension reveal molecular differences in placental proteome in rodents. Physiological Genomics, 53, pp. 259-268. (doi: 10.1152/physiolgenomics.00160.2020)

Maznyczka, A. M., Carrick, D., Oldroyd, K. G., James-Rae, G., McCartney, P., Greenwood, J. P., Good, R., McEntegart, M., Eteiba, H., Lindsay, M., Cotton, J. M., Petrie, M. C., Berry, C. (2021) Thermodilution-derived temperature recovery time, a novel predictor of microvascular reperfusion and prognosis after myocardial infarction. EuroIntervention, 17, pp. 220-228. (doi: 10.4244/EIJ-D-19-00904)

Jhund, P. S., Ponikowski, P., Docherty, K. F., Gasparyan, S. B., Böhm, M., Chang, C.-E., Desai, A. S., Howlett, J., Kitakaze, M., Petrie, M. C., Verma, S., Bengtsson, O., Langkilde, A.-M., Sjöstrand, M., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2021) Dapagliflozin and recurrent heart failure hospitalizations in heart failure with reduced ejection fraction: an analysis of DAPA-HF. Circulation, 143, pp. 1962-1972. (doi: 10.1161/CIRCULATIONAHA.121.053659)

Rossitto, G., Maiolino, G., Lerco, S., Ceolotto, G., Blackburn, G., Mary, S., Antonelli, G., Berton, C., Bisogni, V., Cesari, M., Seccia, T. M., Lenzini, L., Pinato, A., Montezano, A., Touyz, R. M., Petrie, M. C., Daly, R., Welsh, P., Plebani, M., Rossi, G. P., Delles, C. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117, pp. 1372-1381. (doi: 10.1093/cvr/cvaa205)

Tomaz, S. A., Coffee, P., Ryde, G. C., Swales, B., Neely, K. C., Connelly, J., Kirkland, A., McCabe, L., Watchman, K., Andreis, F., Martin, J. G., Pina, I., Whittaker, A. C. (2021) Loneliness, wellbeing, and social activity in Scottish older adults resulting from social distancing during the COVID-19 pandemic. International Journal of Environmental Research and Public Health, 18, (doi: 10.3390/ijerph18094517)

Niven, A., Ryde, G. C., Wilkinson, G., Greenwood, C., Gorely, T. (2021) The effectiveness of an annual nationally delivered workplace step count challenge on changing step counts: Findings from four years of delivery. International Journal of Environmental Research and Public Health, 18, (doi: 10.3390/ijerph18105140)

Connelly, P. J., Azizi, Z., Alipour, P., Delles, C., Pilote, L., Raparelli, V. (2021) The importance of gender to understand sex differences in cardiovascular disease. Canadian Journal of Cardiology, 37, pp. 699-710. (doi: 10.1016/j.cjca.2021.02.005)

Mooney, L., Goodyear, C. S., Chandra, T., Kirschner, K., Copland, M., Petrie, M. C., Lang, N. N. (2021) Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure. Clinical Science, 135, pp. 991-1007. (doi: 10.1042/CS20200306)

Vlahou, A. et al. (2021) Data sharing under the General Data Protection Regulation: time to harmonize law and research ethics? Hypertension, 77, pp. 1029-1035. (doi: 10.1161/HYPERTENSIONAHA.120.16340)

Scott, K., Morgan, H. L., Delles, C., Fisher, S., Graham, D., McBride, M. W. (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53, pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020)

Dewan, P., Docherty, K. F., Bengtsson, O., de Boer, R. A., Desai, A. S., Drozdz, J., Hawkins, N. M., Inzucchi, S. E., Kitakaze, M., Køber, L., Kosiborod, M. N., Langkilde, A. M., Lindholm, D., Martinez, F. A., Merkely, B., Petrie, M. C., Ponikowski, P., Sabatine, M. S., Schou, M., Sjöstrand, M., Solomon, S. D., Verma, S., Jhund, P. S., McMurray, J. J.V. (2021) Effects of dapagliflozin in heart failure with reduced ejection fraction, and chronic obstructive pulmonary disease: an analysis of DAPA-HF. European Journal of Heart Failure, 23, pp. 632-643. (doi: 10.1002/ejhf.2083)

Butt, J. H., Nicolau, J. C., Verma, S., Docherty, K. F., Petrie, M. C., Inzucchi, S. E., Schou, M., Kosiborod, M. N., Langkilde, A. M., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., Bengtsson, O., Jhund, P. S., McMurray, J., Køber, L. (2021) Efficacy and safety of dapagliflozin according to aetiology in heart failure with reduced ejection fraction: insights from the DAPA-HF trial. European Journal of Heart Failure, 23, pp. 601-613. (doi: 10.1002/ejhf.2124)

Mbakwem, A. C., Bauersachs, J., Viljoen, C., Hoevelmann, J., Meer, P., Petrie, M. C., Mebazaa, A., Goland, S., Karaye, K., Laroche, C., Sliwa, K. (2021) Electrocardiographic features and their echocardiographic correlates in peripartum cardiomyopathy: results from the ESC EORP PPCM registry. ESC Heart Failure, 8, pp. 879-889. (doi: 10.1002/ehf2.13172)

Sliwa, K. et al. (2021) Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European Journal of Heart Failure, 23, pp. 527-540. (doi: 10.1002/ejhf.2133)

Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2021) Inflammation and salt in young adults: the African-PREDICT study. European Journal of Nutrition, 60, pp. 873-882. (doi: 10.1007/s00394-020-02292-3)

Neves, K. B., Morris, H., Alves-Lopes, R., Muir, K. W., Moreton, F., Delles, C., Montezano, A. C., Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135, pp. 753-773. (doi: 10.1042/CS20201412)

Tomasoni, D., Petrie, M. C., Adamo, M., Metra, M. (2021) Renin-angiotensin-aldosterone inhibitors and COVID-19: nearing the end of a media-fuelled controversy. European Journal of Heart Failure, 23, pp. 486-488. (doi: 10.1002/ejhf.2098)

Lee, M. M.Y. et al. (2021) Invasive versus medically managed acute coronary syndromes with prior bypass (CABG-ACS): insights into the registry versus randomised trial populations. Open Heart, 8, (doi: 10.1136/openhrt-2020-001453)

Ehteshami-Afshar, S., Mooney, L., Dewan, P., Desai, A. S., Lang, N. N., Lefkowitz, M. P., Petrie, M. C., Rizkala, A. R., Rouleau, J. L., Solomon, S. D., Swedberg, K., Shi, V. C., Zile, M. R., Packer, M., McMurray, J. J.V., Jhund, P. S., Hawkins, N. M. (2021) Clinical characteristics and outcomes of patients with heart failure with reduced ejection fraction and chronic obstructive pulmonary disease: insights from PARADIGM-HF. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.120.019238)

Lee, M. M.Y. et al. (2021) Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 143, pp. 516-525. (doi: 10.1161/CIRCULATIONAHA.120.052186)

Petrie, M. C., Lee, M. M., Lang, N. N. (2021) EMPEROR-REDUCED reigns while EMPERIAL whimpers. European Heart Journal, 42, pp. 711-714. (doi: 10.1093/eurheartj/ehaa965)

Maznyczka, A. M., McCartney, P., Duklas, P., McEntegart, M., Oldroyd, K., Greenwood, J., Muir, D., Chowdhary, S., Gershlick, A. H., Eteiba, H., Cotton, J., Wragg, A., Curzen, N., Tait, R., Macfarlane, P., Welsh, P., Sattar, N., Petrie, M., Ford, I., Fox, K., McConnachie, A., Berry, C. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107, pp. 299-312. (doi: 10.1136/heartjnl-2020-317828)

Docherty, K. F., Campbell, R. T., Brooksbank, K. J.M., Godeseth, R. L., Forsyth, P., McConnachie, A., Roditi, G., Stanley, B., Welsh, P., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2021) Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling. ESC Heart Failure, 8, pp. 129-138. (doi: 10.1002/ehf2.13137)

Connelly, P. J., Clark, A., Touyz, R. M., Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review. Journal of Hypertension, 39, pp. 223-230. (doi: 10.1097/HJH.0000000000002632)

Moreton, F. C., Cullen, B., Dickie, D. A., Lopez Gonzalez, R., Santosh, C., Delles, C., Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28, pp. 220-228. (doi: 10.1111/ene.14534)

Dobbin, S. J.H., Petrie, M. C., Myles, R. C., Touyz, R. M., Lang, N. N. (2021) Cardiotoxic effects of angiogenesis inhibitors. Clinical Science, 135, pp. 71-100. (doi: 10.1042/CS20200305)

Small, H. Y., Delles, C. (2021) Letter to the Editor regarding Cunningham et al. 2020. Hypertension in Pregnancy, 40, pp. 133. (doi: 10.1080/10641955.2021.1899201)

2020

Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)

Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116, pp. 2185-2196. (doi: 10.1093/cvr/cvaa209)

Ferreira, J. P., Docherty, K. F., Stienen, S., Jhund, P. S., Claggett, B. L., Solomon, S. D., Petrie, M. C., Gregsone, J., Pocock, S. L., Zannad, F., McMurray, J. (2020) Estimating the lifetime benefits of treatments for heart failure. JACC: Heart Failure, 8, pp. 984-995. (doi: 10.1016/j.jchf.2020.08.004)

Zamai, N., Cortie, C. H., Jarvie, E. M., Onyiaodike, C. C., Alrehaili, A., Francois, M., Freeman, D. J., Meyer, B. J. (2020) In pregnancy, maternal HDL is specifically enriched in, and carries the highest proportion of, DHA in plasma. Prostaglandins, Leukotrienes and Essential Fatty Acids, 163, (doi: 10.1016/j.plefa.2020.102209)

Mackenzie, I. S. et al. (2020) Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial. Lancet, 396, pp. 1745-1757. (doi: 10.1016/S0140-6736(20)32234-0)

Beazer, J. D., Patanapirunhakit, P., Gill, J. M.R., Graham, D., Karlsson, H., Ljunggren, S., Mulder, M., Freeman, D. J. (2020) High-density lipoprotein’s vascular protective functions in metabolic and cardiovascular disease - could extracellular vesicles be at play? Clinical Science, 134, pp. 2977-2986. (doi: 10.1042/CS20200892)

McEwan, P., Darlington, O., McMurray, J. J.V., Jhund, P. S., Docherty, K. F., Böhm, M., Petrie, M. C., Bergenheim, K., Qin, L. (2020) Cost-effectiveness of dapagliflozin as a treatment for heart failure with reduced ejection fraction: a multinational health-economic analysis of DAPA-HF. European Journal of Heart Failure, 22, pp. 2147-2156. (doi: 10.1002/ejhf.1978)

Ferreira, J. P., Dewan, P., Jhund, P., Lorenzo-Almorós, A., Duarte, K., Petrie, M., Carson, P. E., McKelvie, R., Komajda, M., Zile, M., Zannad, F., McMurray, J. J.V. (2020) Covariate adjusted reanalysis of the I-Preserve trial. Clinical Research in Cardiology, 109, pp. 1358-1365. (doi: 10.1007/s00392-020-01632-x)

Seferović, P. M. et al. (2020) Heart Failure Association of the European Society of Cardiology update on sodium glucose co‐transporter‐2 inhibitors in heart failure (an update on the Sodium–glucose co‐transporter 2 inhibitors in heart failure: beyond glycaemic control. The position paper of the Heart Failure Association of the European Society of Cardiology) European Journal of Heart Failure, 22, pp. 1984-1986. (doi: 10.1002/ejhf.2026)

McCartney, P. J. et al. (2020) Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT. Efficacy and Mechanism Evaluation, 7, (doi: 10.3310/eme07050)

Dewan, P., Jackson, A., Jhund, P. S., Shen, L., Ferreira, J. P., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Køber, L., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2020) The prevalence and importance of frailty in heart failure with reduced ejection fraction – an analysis of PARADIGM-HF and ATMOSPHERE. European Journal of Heart Failure, 22, pp. 2123-2133. (doi: 10.1002/ejhf.1832)

Lang, N. N., Dobbin, S. J.H., Petrie, M. C. (2020) Vericiguat in worsening heart failure – agonising over, or celebrating, agonism. Cardiovascular Research, 116, pp. e152-e155. (doi: 10.1093/cvr/cvaa247)

Butt, J. H., Fosbøl, E. L., Gerds, T. A., Andersson, C., McMurray, J. J.V., Petrie, M. C., Gustafsson, F., Madelaire, C., Kristensen, S. L., Gislason, G. H., Torp-Pedersen, C., Køber, L., Schou, M. (2020) Readmission and death in patients admitted with new-onset versus worsening of chronic heart failure: insights from a nationwide cohort. European Journal of Heart Failure, 22, pp. 1777-1785. (doi: 10.1002/ejhf.1800)

Dowsett, L., Higgins, E., Alanazi, S., Alshuwayer, N. A., Leiper, F. C., Leiper, J. (2020) ADMA: A key player in the relationship between vascular dysfunction and inflammation in atherosclerosis. Journal of Clinical Medicine, 9, (doi: 10.3390/jcm9093026)

Seferović, P. M. et al. (2020) Sodium–glucose co‐transporter 2 inhibitors in heart failure: beyond glycaemic control. A position paper of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 22, pp. 1495-1503. (doi: 10.1002/ejhf.1954)

Rossitto, G., Mary, S., Chen, J. Y., Bodder, P., Chew, K. S., Neves, K. B., Alves, R. L., Montezano, A. C., Welsh, P., Petrie, M. C., Graham, D., Touyz, R. M., Delles, C. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, (doi: 10.1038/s41467-020-17820-2)

Connelly, P. J., Jandeleit-Dahm, K. A.M., Delles, C. (2020) Sex and gender aspects in vascular pathophysiology. Clinical Science, 134, pp. 2203-2207. (doi: 10.1042/CS20200876)

Campbell, R. T., Jasilek, A., Mischak, H., Nkuipou-Kenfack, E., Latosinska, A., Welsh, P. I., Jackson, C. E., Cannon, J., McConnachie, A., Delles, C., McMurray, J. J.V. (2020) The novel urinary proteomic classifier HF1 has similar diagnostic and prognostic utility to BNP in heart failure. ESC Heart Failure, 7, pp. 1595-1604. (doi: 10.1002/ehf2.12708)

Demin, A., Løge, B., Zhiteneva, O., Nishida, C., Whiting, S., Rippin, H., Delles, C., Karymbaeva, S., Wickramasinghe, K., Breda, J. (2020) Trans fatty acid elimination policy in member states of the Eurasian Economic Union: implementation challenges and capacity for enforcement. Journal of Clinical Hypertension, 22, pp. 1328-1337. (doi: 10.1111/jch.13945)

Tarar, O. M., Ahmed, K. M., Nishtar, N. A., Achakzai, A. B. K., Gulzar, Y., Delles, C., Al-Jawaldeh, A. (2020) Understanding the complexities of prevalence of trans fat and its control in food supply in Pakistan. Journal of Clinical Hypertension, 22, pp. 1338-1346. (doi: 10.1111/jch.13943)

Dobbie, L. J., Mackin, S. T., Hogarth, K., Lonergan, F., Kannenkeril, D., Brooksbank, K., Delles, C. (2020) Validation of semi-automated flow mediated dilation measurement in healthy volunteers. Blood Pressure Monitoring, 25, pp. 216-223. (doi: 10.1097/MBP.0000000000000448)

Bulluck, H., Carberry, J., Carrick, D., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Mahrous, A., Ford, I., Oldroyd, K. G., Berry, C. (2020) Redefining adverse and reverse left ventricular remodeling by cardiovascular magnetic resonance following ST-segment elevation myocardial infarction and their implications on long-term prognosis. Circulation: Cardiovascular Imaging, 13, (doi: 10.1161/CIRCIMAGING.119.009937)

Dobbin, S. J.H., Mangion, K., Berry, C., Roditi, G., Basak, S., Sourbron, S., White, J., Venugopal, B., Touyz, R. M., Jones, R. J., Petrie, M. C., Lang, N. N. (2020) Cardiotoxicity and myocardial hypoperfusion associated with anti-VEGF therapies: prospective cardiac magnetic resonance imaging in patients with cancer. European Journal of Heart Failure, 22, pp. 1276-1277. (doi: 10.1002/ejhf.1847)

Docherty, K. F., Jhund, P. S., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Ponikowski, P., DeMets, D. L., Sabatine, M. S., Bengtsson, O., Sjöstrand, M., Langkilde, A. M., Desai, A. S., Diez, M., Howlett, J. G., Katova, T., Ljungman, C. E. A., O’Meara, E., Petrie, M. C., Schou, M., Verma, S., Vinh, P. N., Solomon, S. D., McMurray, J. J.V. (2020) Effects of dapagliflozin in DAPA-HF according to background heart failure therapy. European Heart Journal, 41, pp. 2379-2392. (doi: 10.1093/eurheartj/ehaa183)

Currie, G., Mary, S., Delles, C. (2020) Is there a role for proteomics in diabetic renal disease? NDT Plus, 35, pp. 1133-1135. (doi: 10.1093/ndt/gfz017)

Derakhshan, A. et al. (2020) Association of maternal thyroid function with birth weight: a systematic review and individual-participant data meta-analysis. Lancet Diabetes and Endocrinology, 8, pp. 501-510. (doi: 10.1016/S2213-8587(20)30061-9)

Picone, D. S., Deshpande, R. A., Schultz, M. G., Fonseca, R., Campbell, N. R.C., Delles, C., Hecht-Olsen, M., Schutte, A. E., Stergiou, G., Padwal, R., Zhang, X.-H., Sharman, J. E. (2020) Nonvalidated home blood pressure devices dominate the online marketplace in Australia: major implications for cardiovascular risk management. Hypertension, 75, pp. 1593-1599. (doi: 10.1161/hypertensionaha.120.14719)

Delles, C., Olfert, M. (2020) Electronic cigarettes: how bad are they for your health? Cardiovascular Research, 116, pp. e64-e66. (doi: 10.1093/cvr/cvaa041)

Maznyczka, A. M., Oldroyd, K. G., Greenwood, J. P., McCartney, P. J., Cotton, J., Lindsay, M., McEntegart, M., Rocchiccioli, J. P., Good, R., Robertson, K., Eteiba, H., Watkins, S., Shaukat, A., Petrie, C. J., Murphy, A., Petrie, M. C., Berry, C. (2020) Comparative significance of invasive measures of microvascular injury in acute myocardial infarction. Circulation: Cardiovascular Interventions, 13, (doi: 10.1161/CIRCINTERVENTIONS.119.008505)

Hawkins, N. M., Osmanska, J., Petrie, M. C. (2020) Implantable cardioverter-defibrillators and survival - the fine line between efficacy concerns and ageism. European Journal of Heart Failure, 22, pp. 868-870. (doi: 10.1002/ejhf.1803)

Hennigan, B., Berry, C., Collison, D., Corcoran, D., Eteiba, H., Good, R., McEntegart, M., Watkins, S., McClure, J., Mangion, K., Ford, T., Petrie, M. C., Hood, S., Rocchiccioli, P., Shaukat, A., Lindsay, M., Oldroyd, K. G. (2020) Percutaneous coronary intervention versus medical therapy in patients with angina and grey-zone fractional flow reserve values: a randomised clinical trial. Heart, 106, pp. 714-715. (doi: 10.1136/heartjnl-2019-316075)

Docherty, K. F., Ferreira, J. P., Sharma, A., Girerd, N., Gregson, J., Duarte, K., Petrie, M. C., Jhund, P. S., Dickstein, K., Pfeffer, M. A., Pitt, B., Rossignol, P., Zannad, F., McMurray, J. J.V. (2020) Predictors of sudden cardiac death in high-risk patients following a myocardial infarction. European Journal of Heart Failure, 22, pp. 848-855. (doi: 10.1002/ejhf.1694)

Petrie, M. C., et al. (2020) Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes. JAMA: Journal of the American Medical Association, 323, pp. 1353-1368. (doi: 10.1001/jama.2020.1906)

Nosalski, R., Siedlinski, M., Denby, L., Mcginnigle, E., Nowak, M., Nguyen Dinh Cat, A., Medina-Ruiz, L., Cantini, M., Skiba, D., Wilk, G., Osmenda, G., Rodor, J., Salmeron-Sanchez, M., Graham, G., Maffia, P., Graham, D., Baker, A. H., Guzik, T. J. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428)

Ryde, G. C., Atkinson, P., Stead, M., Gorely, T., Evans, J. M. M. (2020) Physical activity in paid work time for desk-based employees: a qualitative study of employers’ and employees’ perspectives. BMC Public Health, 20, (doi: 10.1186/s12889-020-08580-1)

Delles, C., Li, H., Touyz, R. M. (2020) ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19. Clinical Science, 134, pp. 747-750. (doi: 10.1042/CS20200363)

Tofte, N. et al. (2020) Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial. Lancet Diabetes and Endocrinology, 8, pp. 301-312. (doi: 10.1016/S2213-8587(20)30026-7)

Frazier, S., McBride, M. W., Mulvana, H., Graham, D. (2020) From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia. Clinical Science, 134, pp. 1001-1025. (doi: 10.1042/CS20200023)

Simpson, J., Jhund, P. S., Lund, L. H., Padmanabhan, S., Clagget, B. L., Shen, L., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Kober, L., Paker, M., Rouleau, J. L., Mueller-Velten, G., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2020) Prognostic models derived in PARADIGM-HF and validated in ATMOSPHERE and the Swedish Heart Failure Registry to predict mortality and morbidity in chronic heart failure. JAMA Cardiology, 5, pp. 432-441. (doi: 10.1001/jamacardio.2019.5850)

Metcalfe, R. S., Atef, H., Mackintosh, K., McNarry, M., Ryde, G., Hill, D. M., Vollaard, N. B. J. (2020) Time-efficient and computer-guided sprint interval exercise training for improving health in the workplace: a randomised mixed-methods feasibility study in office-based employees. BMC Public Health, 20, (doi: 10.1186/s12889-020-8444-z)

Lee, M. M.Y., Petrie, M. C., McMurray, J. J.V., Sattar, N. (2020) How do SGLT2 (sodium-glucose cotransporter 2) inhibitors and GLP-1 (glucagon-like peptide-1) receptor agonists reduce cardiovascular outcomes? Arteriosclerosis, Thrombosis, and Vascular Biology, 40, pp. 506-522. (doi: 10.1161/atvbaha.119.311904)

Jarvie, E., Stewart, F., Ramsay, J. E., Brown, E. A., Meyer, B., Olivecrona, G., Griffin, B., Freeman, D. (2020) Maternal adipose tissue expansion, a missing link in the prediction of birth weight centile. Journal of Clinical Endocrinology and Metabolism, 105, pp. e814-e825. (doi: 10.1210/clinem/dgz248)

Docherty, K. F., Shen, L., Castagno, D., Petrie, M. C., Abraham, W. T., Böhm, M., Desai, A. S., Dickstein, K., Køber, L. V., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Vazir, A., Zile, M. R., Jhund, P. S., McMurray, J. J.V. (2020) Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction. European Journal of Heart Failure, 22, pp. 528-538. (doi: 10.1002/ejhf.1682)

Serenelli, M., Jackson, A., Dewan, P., Jhund, P. S., Petrie, M. C., Rossignol, P., Campo, G., Pitt, B., Zannad, F., Ferreira, J. P., McMurray, J. J.V. (2020) Mineralocorticoid receptor antagonists, blood pressure, and outcomes in heart failure with reduced ejection fraction. JACC: Heart Failure, 8, pp. 188-198. (doi: 10.1016/j.jchf.2019.09.011)

Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2020) Distinct inflammatory mediator patterns in young black and white adults: The African-PREDICT study. Cytokine, 126, (doi: 10.1016/j.cyto.2019.154894)

Seferović, P. M. et al. (2020) European Society of Cardiology/Heart Failure Association position paper on the role and safety of new glucose‐lowering drugs in patients with heart failure. European Journal of Heart Failure, 22, pp. 196-213. (doi: 10.1002/ejhf.1673)

Maznyczka, A. M. et al. (2020) One-year outcomes after low-dose intracoronary alteplase during primary percutaneous coronary intervention. The T-TIME randomized trial. Circulation: Cardiovascular Interventions, 13, (doi: 10.1161/CIRCINTERVENTIONS.119.008855)

Ford, T. J., Khan, A., Docherty, K. F., Jackson, A., Morrow, A., Sidik, N., Rocchiccioli, P., Good, R., Eteiba, H., Watkins, S., Shaukat, A., Lindsay, M., Robertson, K., Petrie, M., Berry, C., Oldroyd, K., McEntegart, M. (2020) Sex differences in procedural and clinical outcomes following rotational atherectomy. Catheterization and Cardiovascular Interventions, 95, pp. 232-241. (doi: 10.1002/ccd.28373)

Schlosser, K., Kaur, A., Dayan, N., Stewart, D. J., Pilote, L., Delles, C. (2020) Circulating miR-206 and Wnt-signaling are associated with cardiovascular complications and a history of preeclampsia in women. Clinical Science, 134, pp. 87-101. (doi: 10.1042/CS20190920)

Kosiborod, M. N., Jhund, P., Docherty, K. F., Diez, M., Petrie, M. C., Verma, S., Nicolau, J. C., Merkely, B., Kitakaze, M., DeMets, D. L., Inzucchi, S. E., Køeber, L., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Bengtsson, O., Lindholm, D., Niklasson, A., Sjöstrand, M., Langkilde, A. M., McMurray, J. J.V. (2020) Effects of dapagliflozin on symptoms, function and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial. Circulation, 141, pp. 90-99. (doi: 10.1161/CIRCULATIONAHA.119.044138)

Martinez, F. A., Serenelli, M., Nicolau, J. C., Petrie, M. C., Chiang, C.-E., Tereshchenko, S., Solomon, S. D., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Ponikowski, P., Sabatine, M. S., DeMets, D. L., Dutkiewicz-Piasecka, M., Bengtsson, O., Sjöstrand, M., Langkilde, A. M., Jhund, P., McMurray, J. J.V. (2020) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to age: insights from DAPA-HF. Circulation, 141, pp. 100-111. (doi: 10.1161/CIRCULATIONAHA.119.044133)

Mary, S., Currie, G., Schutte, A. E., Delles, C. (2020) Cardiovascular proteomics. Academic Press

Heggie, R., Wu, O., Boyd, K., Lee, M. M.Y., Petrie, M. C., McEntegart, M., Berry, C. (2020) Does routine invasive management benefit patients presenting with an acute coronary syndrome and a history of bypass surgery? The use of clinical outcomes compared with cost-effectiveness outcomes.

2019

Dewan, P., Rorth, R., Raparelli, V., Campbell, R. T., Shen, L., Jhund, P. S., Petrie, M. C., Anand, I. S., Carson, P. E., Desai, A. S., Granger, C. B., Køber, L., Komajda, M., McKelvie, R. S., O'Meara, E., Pfeffer, M. A., Pitt, B., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Sex-related differences in heart failure with preserved ejection fraction. Circulation: Heart Failure, 12, (doi: 10.1161/CIRCHEARTFAILURE.119.006539)

Neves, K. B., Harvey, A. P., Moreton, F., Montezano, A. C., Rios, F. J., Alves-Lopes, R., Nguyen Dinh Cat, A., Rocchiccioli, P., Delles, C., Joutel, A., Muir, K., Touyz, R. M. (2019) ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. JCI Insight, 4, (doi: 10.1172/jci.insight.131344)

Connelly, P. J., Freel, E. M., Perry, C., Ewan, J., Touyz, R. M., Currie, G., Delles, C. (2019) Gender-affirming hormone therapy, vascular health and cardiovascular disease in transgender adults. Hypertension, 74, pp. 1266-1274. (doi: 10.1161/HYPERTENSIONAHA.119.13080)

Cameron, A. C., Lang, N. N., Dominiczak, A. F., Jennings, G. L.R., Batlle, D., Bursztyn, M., Chugh, A. R., Floras, J. S., Taler, S. J., Touyz, R. M., Delles, C. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74, pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343)

McMurray, J. J.V. et al. (2019) Dapagliflozin in patients with heart failure and reduced ejection fraction. New England Journal of Medicine, 381, pp. 1995-2008. (doi: 10.1056/NEJMoa1911303)

Stirrat, C. G., Alam, S., MacGillivray, T. J., Gray, C., Dweck, M. R., Jones, V., Wallace, W., Payne, J. R., Prasad, S. K., Gardner, R. S., Petrie, M. C., Mirsadraee, S., Henriksen, P., Newby, D. E., Semple, S. (2019) Ferumoxytol-enhanced MRI in patients with prior cardiac transplantation. Open Heart, 6, (doi: 10.1136/openhrt-2019-001115)

Howlett, J. G., Stebbins, A., Petrie, M. C., Jhund, P. S., Castelvecchio, S., Cherniavsky, A., Sueta, C. A., Roy, A., Piña, I. L., Wurm, R., Drazner, M. H., Andersson, B., Batlle, C., Senni, M., Chrzanowski, L., Merkely, B., Carson, P., Desvigne-Nickens, P. M., Lee, K. L., Velazquez, E. J., Al-Khalidi, H. R. (2019) CABG improves outcomes in patients with ischemic cardiomyopathy 10-year follow-up of the STICH trial. JACC: Heart Failure, 7, pp. 878-887. (doi: 10.1016/j.jchf.2019.04.018)

Packer, M. et al. (2019) Evaluation of the effect of sodium–glucose co‐transporter 2 inhibition with empagliflozin on morbidity and mortality of patients with chronic heart failure and a reduced ejection fraction: rationale for and design of the EMPEROR‐Reduced trial. European Journal of Heart Failure, 21, pp. 1270-1278. (doi: 10.1002/ejhf.1536)

Anker, S. D. et al. (2019) Evaluation of the effects of sodium–glucose co‐transporter 2 inhibition with empagliflozin on morbidity and mortality in patients with chronic heart failure and a preserved ejection fraction: rationale for and design of the EMPEROR‐Preserved Trial. European Journal of Heart Failure, 21, pp. 1279-1287. (doi: 10.1002/ejhf.1596)

Nicolau, J. C., Stevens, S. R., Al-Khalidi, H. R., Jatene, F. B., Furtado, R. H.M., Dallan, L. A.O., Lisboa, L. A.F., Desvigne-Nickens, P., Haddad, H., Jolicoeur, E. M., Petrie, M. C., Doenst, T., Michler, R. E., Ohman, E. M., Maddury, J., Ali, I., Deja, M. A., Rouleau, J. L., Velazquez, E. J., Hill, J. A. (2019) Does prior coronary angioplasty affect outcomes of surgical coronary revascularization? Insights from the STICH trial. International Journal of Cardiology, 291, pp. 36-41. (doi: 10.1016/j.ijcard.2019.03.029)

Kristensen, S. L., Rorth, R., Jhund, P. S., Docherty, K., Sattar, N., Preiss, D., Kober, L., Petrie, M. C., McMurray, J. J.V. (2019) Cardiovascular, mortality and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet Diabetes and Endocrinology, 7, pp. 776-785. (doi: 10.1016/S2213-8587(19)30249-9)

Iliodromiti, S., Sattar, N., Delles, C., Nelson, S. M., Gill, J. M.R., Lumsden, M. (2019) Menopausal hot flashing and endothelial function in two vascular beds: findings from a cross-sectional study of postmenopausal women. Menopause, 26, pp. 1002-1009. (doi: 10.1097/GME.0000000000001386)

Korevaar, T. I. M. et al. (2019) Association of thyroid function test abnormalities and thyroid autoimmunity with preterm birth: a systematic review and meta-analysis. JAMA: Journal of the American Medical Association, 322, pp. 632-641. (doi: 10.1001/jama.2019.10931)

Rørth, R., Dewan, P., Kristensen, S. L., Jhund, P. S., Petrie, M. C., Køber, L., McMurray, J. J.V. (2019) Efficacy of an implantable cardioverter-defibrillator in patients with diabetes and heart failure and reduced ejection fraction. Clinical Research in Cardiology, 108, pp. 868-877. (doi: 10.1007/s00392-019-01415-z)

Shen, L., Rørth, R., Cosmi, D., Kristensen, S. L., Petrie, M. C., Cosmi, F., Latini, R., Køber, L., Anand, I. S., Carson, P. E., Granger, C. B., Komajda, M., McKelvie, R. S., Solomon, S. D., Staszewsky, L., Swedberg, K., Huynh, T., Zile, M. R., Jhund, P. S., McMurray, J. J.V. (2019) Insulin treatment and clinical outcomes in patients with diabetes and heart failure with preserved ejection fraction. European Journal of Heart Failure, 21, pp. 974-984. (doi: 10.1002/ejhf.1535)

Lee, M. M.Y. et al. (2019) Invasive versus medical management in patients with prior coronary artery bypass surgery with a non-ST segment elevation acute coronary syndrome: a pilot randomized controlled trial. Circulation: Cardiovascular Interventions, 12, (doi: 10.1161/CIRCINTERVENTIONS.119.007830)

Bauersachs, J., König, T., Meer, P., Petrie, M. C., Hilfiker‐Kleiner, D., Mbakwem, A., Hamdan, R., Jackson, A. M., Forsyth, P., Boer, R. A., Mueller, C., Lyon, A. R., Lund, L. H., Piepoli, M. F., Heymans, S., Chioncel, O., Anker, S. D., Ponikowski, P., Seferovic, P. M., Johnson, M. R., Mebazaa, A., Sliwa, K. (2019) Pathophysiology, diagnosis and management of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on peripartum cardiomyopathy. European Journal of Heart Failure, 21, pp. 827-843. (doi: 10.1002/ejhf.1493)

Cleland, J. G.F., Hindricks, G., Petrie, M. (2019) The shocking lack of evidence for implantable cardioverter defibrillators for heart failure; with or without cardiac resynchronization. European Heart Journal, 40, pp. 2128-2130. (doi: 10.1093/eurheartj/ehz409)

Mikolajczyk, T. P., Nosalski, R., Skiba, D. S., Koziol, J., Mazur, M., Justo Junior, A. S., Kowalczyk, P., Kusmierczyk, Z., Schramm Luc, A., Luc, K., Maffia, P., Graham, D., Kiss, A. K., Naruszewicz, M., Guzik, T. J. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176, pp. 1951-1965. (doi: 10.1111/bph.14583)

Clark, A. L., Kalra, P. R., Petrie, M. C., Mark, P. B., Tomlinson, L. A., Tomson, C. R.V. (2019) Change in renal function associated with drug treatment in heart failure: national guidance. Heart, 105, pp. 904-910. (doi: 10.1136/heartjnl-2018-314158)

Bagot, C.N., Leishman, E., Onyiaodike, C.C., Jordan, F., Gibson, V.B., Freeman, D.J. (2019) Changes in laboratory markers of thrombotic risk early in the first trimester of pregnancy may be linked to an increase in estradiol and progesterone. Thrombosis Research, 178, pp. 47-53. (doi: 10.1016/j.thromres.2019.03.015)

Haig, C., Carrick, D., Carberry, J., Mangion, K., Maznyczka, A., Wetherall, K., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ahmed, N., May, V. T. Y., Ford, I., Radjenovic, A., Welsh, P., Sattar, N., Oldroyd, K. G., Berry, C. (2019) Current smoking and prognosis after acute ST-segment elevation myocardial infarction: new pathophysiological insights. JACC: Cardiovascular Imaging, 12, pp. 993-1003. (doi: 10.1016/j.jcmg.2018.05.022)

Ahmad, F. A., Petrie, M. C., McMurray, J. J.V., Lang, N. N. (2019) Personalized medicine and hospitalization for heart failure: if we understand it, we may be successful in treating it. European Journal of Heart Failure, 21, pp. 699-702. (doi: 10.1002/ejhf.1463)

Czesnikiewicz-Guzik, M., Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D., Harrison, D. G., Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176, pp. 1922-1931. (doi: 10.1111/bph.14536)

Welsh, C., Welsh, P., Jhund, P., Delles, C., Celis-Morales, C., Lewsey, J., Gray, S., Lyall, D., Iliodromiti, S., Gill, J., Sattar, N., Mark, P. (2019) Urinary sodium excretion, blood pressure and risk of future cardiovascular disease and mortality in subjects without prior cardiovascular disease. Hypertension, 73, pp. 1202-1209. (doi: 10.1161/HYPERTENSIONAHA.119.12726)

Ryde, G. C., Dreczkowski, G., Gallagher, I., Chesham, R., Gorely, T. (2019) Device-measured desk-based occupational sitting patterns and stress (hair cortisol and perceived stress) International Journal of Environmental Research and Public Health, 16, (doi: 10.3390/ijerph16111906)

Chesham, R. A., Booth, J. N., Sweeney, E. L., Ryde, G. C., Gorely, T., Brooks, N. E., Moran, C. N. (2019) Response to Daly-Smith et al.’s commentary on ‘The Daily Mile makes primary school children more active, less sedentary and improves their fitness and body composition: a quasi-experimental pilot study’ BMC Medicine, 17, (doi: 10.1186/s12916-019-1336-3)

Schanstra, J. P., Luong, T. T.D., Makridakis, M., Van Linthout, S., Lygirou, V., Latosinska, A., Alesutan, I., Boehme, B., Schelski, N., Von Lewinski, D., Mullen, W., Nicklin, S., Delles, C., Feuillet, G., Denis, C., Lang, F., Pieske, B., Bascands, J.-L., Mischak, H., Saulnier-Blache, J.-S., Voelkl, J., Vlahou, A., Klein, J. (2019) Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment. JCI Insight, 4, (doi: 10.1172/jci.insight.125638)

Small, H. Y., McNeilly, S., Mary, S., Sheikh, A. M., Delles, C. (2019) Resistin mediates sex-dependent effects of perivascular adipose tissue on vascular function in the SHRSP. Scientific Reports, 9, (doi: 10.1038/s41598-019-43326-z)

McMurray, J. J.V. et al. (2019) A trial to evaluate the effect of the sodium–glucose co‐transporter 2 inhibitor dapagliflozin on morbidity and mortality in patients with heart failure and reduced left ventricular ejection fraction (DAPA‐HF) European Journal of Heart Failure, 21, pp. 665-675. (doi: 10.1002/ejhf.1432)

Dewan, P. et al. (2019) Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas. European Journal of Heart Failure, 21, pp. 577-587. (doi: 10.1002/ejhf.1347)

Shen, L., Jhund, P. S., Docherty, K. F., Petrie, M. C., Anand, I. S., Carson, P. E., Desai, A. S., Granger, C. B., Komajda, M., McKelvie, R. S., Pfeffer, M. A., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Prior pacemaker implantation and clinical outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 7, pp. 418-427. (doi: 10.1016/j.jchf.2018.12.006)

Ferreira, J. P. et al. (2019) Proteomic bioprofiles and mechanistic pathways of progression to heart failure: the HOMAGE study. Circulation, 12, (doi: 10.1161/CIRCHEARTFAILURE.118.005897)

Olson, E., Pravenec, M., Landa, V., Koh-Tan, H. H. C., Dominiczak, A. F., McBride, M. W., Graham, D. (2019) Transgenic overexpression of glutathione S-transferase μ-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 37, pp. 985-996. (doi: 10.1097/HJH.0000000000001960)

Currie, G., Delles, C. (2019) Vascular biomedicine in an era of chronic disease and multimorbidity. Clinical Science, 133, pp. 1137-1143. (doi: 10.1042/CS20180764)

Wolsk, E., Kaye, D., Komtebedde, J., Shah, S. J., Borlaug, B. A., Burkhoff, D., Kitzman, D. W., Lam, C. S.P., van Veldhuisen, D. J., Ponikowski, P., Petrie, M. C., Hassager, C., Møller, J. E., Gustafsson, F. (2019) Central and peripheral determinants of exercise capacity in heart failure patients with preserved ejection fraction. JACC: Heart Failure, 7, pp. 321-332. (doi: 10.1016/j.jchf.2019.01.006)

Maznyczka, A. M., Carrick, D., Carberry, J., Mangion, K., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Ford, I., Welsh, P., Sattar, N., Oldroyd, K. G., Berry, C. (2019) Sex-based associations with microvascular injury and outcomes after ST-segment elevation myocardial infarction. Open Heart, 6, (doi: 10.1136/openhrt-2018-000979)

Pettit, S. J., Petrie, M. C. (2019) Transplantation of hearts donated after circulatory-determined death: a song of fire and ice. Circulation: Heart Failure, 12, (doi: 10.1161/CIRCHEARTFAILURE.119.005991)

Januzzi, J., Ferreira, J. P., Böhm, M., Kaul, S., Wanner, C., Brueckmann, M., Petrie, M., Ofstad, A.-P., Zeller, C., George, J., Fitchett, D., Zannad, F. (2019) Empagliflozin reduces the risk of a broad spectrum of heart failure outcomes regardless of heart failure status at baseline. European Journal of Heart Failure, 21, pp. 386-388. (doi: 10.1002/ejhf.1419)

Mangion, K., Carrick, D., Clerfond, G., Rush, C., McComb, C., Oldroyd, K. G., Petrie, M. C., Eteiba, H., Lindsay, M., McEntegart, M., Hood, S., Watkins, S., Davie, A., Auger, D. A., Zhong, X., Epstein, F. H., Haig, C. E., Berry, C. (2019) Predictors of segmental myocardial functional recovery in patients after an acute ST-elevation myocardial infarction. European Journal of Radiology, 112, pp. 121-129. (doi: 10.1016/j.ejrad.2019.01.010)

Loader, J., Chan, Y.-K., A Hawley, J., Moholdt, T., McDonald, C. F., Jhund, P., Petrie, M. C., McMurray, J. J., Scuffham, P. A., Ramchand, J., Burrell, L. M., Stewart, S. (2019) Prevalence and profile of "seasonal frequent flyers" with chronic heart disease: analysis of 1598 patients and 4588 patient-years follow-up. International Journal of Cardiology, 279, pp. 126-132. (doi: 10.1016/j.ijcard.2018.12.060)

Lucas-Herald, A. K., Zürbig, P., Mason, A., Kinning, E., Brown, C. E., Mansoorian, B., Mullen, W., Ahmed, S. F., Delles, C. (2019) Proteomic evidence of biological aging in a child with a compound heterozygous ZMPSTE24 mutation. Proteomics Clinical Applications, 13, (doi: 10.1002/prca.201800135)

Mamet, H., Petrie, M. C., Rocchiccioli, P. (2019) Type 1 diabetes mellitus and coronary revascularization. Cardiovascular Endocrinology and Metabolism, 8, pp. 35-38. (doi: 10.1097/XCE.0000000000000166)

Avtaar Singh, S. S., Das De, S., Nappi, F., Al-Adhami, A., Hegazy, Y., Dalzell, J., Doshi, H., Sinclair, A., Curry, P., Petrie, M., Berry, C., Al-Attar, N. (2019) Mechanical circulatory support for refractory cardiogenic shock post-acute myocardial infarction-a decade of lessons. Journal of Thoracic Disease, 11, pp. 542-548. (doi: 10.21037/jtd.2019.01.21)

Mangion, K., Carrick, D., Carberry, J., Mahrous, A., McComb, C., Oldroyd, K. G., Eteiba, H., Lindsay, M., McEntegart, M., Hood, S., Petrie, M. C., Watkins, S., Davie, A., Zhong, X., Epstein, F. H., Haig, C. E., Berry, C. (2019) Circumferential strain predicts major adverse cardiovascular events following an acute ST-segment-elevation myocardial infarction. Radiology, 290, pp. 329-337. (doi: 10.1148/radiol.2018181253)

Kaye, D. M., Petrie, M. C., McKenzie, S., Hasenfuβ, G., Malek, F., Post, M., Doughty, R. N., Trochu, J.-N., Gustafsson, F., Lang, I., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Hausleiter, J., Raake, P., Jondeau, G., Bergmann, M. W., Spelman, T., Aytug, H., Ponikowski, P., Hayward, C. (2019) Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction. ESC Heart Failure, 6, pp. 62-69. (doi: 10.1002/ehf2.12350)

Lee, M. M.Y., Campbell, R. T., Kelly, R., Petrie, M. C., Sonecki, P. (2019) Does “Scar” at Rest Echocardiography Predict Lack of Contractility Reserve at Dobutamine Stress Echocardiography. (doi: 10.1093/ehjci/jey266)

Dewan, P., Rørth, R., Jhund, P. S., Shen, L., Raparelli, V., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Køber, L., Mogensen, U. M., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Differential impact of heart failure with reduced ejection fraction on men and women. Journal of the American College of Cardiology, 73, pp. 29-40. (doi: 10.1016/j.jacc.2018.09.081)

McCartney, P. J. et al. (2019) Effect of low-dose intracoronary alteplase during primary percutaneous coronary intervention on microvascular obstruction in patients with acute myocardial infarction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321, pp. 56-68. (doi: 10.1001/jama.2018.19802)

Kerr, D. M.I., Brooksbank, K. J.M., Taylor, R. G., Pinel, K., Rios, F. J., Touyz, R. M., Delles, C. (2019) Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study. Journal of Hypertension, 37, pp. 154-166. (doi: 10.1097/HJH.0000000000001890)

Lee, M. M. Y., McMurray, J. J.V., Lorenzo-Almorós, A., Kristensen, S. L., Sattar, N., Jhund, P. S., Petrie, M. C. (2019) Diabetic cardiomyopathy. Heart, 105, pp. 337-345. (doi: 10.1136/heartjnl-2016-310342)

Ravassa, S., Delles, C., Currie, G., Díez, J. (2019) Biomarkers of cardiovascular disease. Springer

Small, H. Y., Currie, G., Delles, C. (2019) Endothelial dysfunction. Springer

Rush, C. J., Petrie, M. C. (2019) Heart failure with preserved ejection fraction. Springer

Logue, J., Sattar, N., Freeman, D. (2019) Obesity. Springer

(2019) Textbook of Vascular Medicine. (doi: 10.1007/978-3-030-16481-2)

Graham, D. (2019) Vascular physiology. Springer

2018

Rossitto, G., Touyz, R. M., Petrie, M. C., Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132, pp. 2609-2613. (doi: 10.1042/CS20180575)

Campbell, R. T., Petrie, M. C., McMurray, J. J.V. (2018) Redefining heart failure phenotypes based on ejection fraction. European Journal of Heart Failure, 20, pp. 1634-1635. (doi: 10.1002/ejhf.1325)

Campbell, R. T., Petrie, M. C., McMurray, J. J.V. (2018) Talking to patients with heart failure about end of life. European Journal of Heart Failure, 20, pp. 1763-1765. (doi: 10.1002/ejhf.1321)

Dobbin, S. J.H., Cameron, A. C., Petrie, M. C., Jones, R. J., Touyz, R. M., Lang, N. N. (2018) Toxicity of cancer therapy: what the cardiologist needs to know about angiogenesis inhibitors. Heart, 104, pp. 1995-2002. (doi: 10.1136/heartjnl-2018-313726)

Sliz, E. et al. (2018) Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment. Circulation, 138, pp. 2499-2512. (doi: 10.1161/CIRCULATIONAHA.118.034942)

Kristensen, S. L., Rørth, R., Jhund, P. S., Shen, L., Lee, M. M.Y., Petrie, M. C., Køber, L., McMurray, J. J.V. (2018) Microvascular complications in diabetes patients with heart failure and reduced ejection fraction-insights from the Beta-blocker Evaluation of Survival Trial. European Journal of Heart Failure, 20, pp. 1549-1556. (doi: 10.1002/ejhf.1201)

Graham, L. A., Aman, A., Campbell, D. D., Augley, J., Graham, D., McBride, M. W., Fraser, N. J., Ferreri, N. R., Dominiczak, A. F., Padmanabhan, S. (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50, pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018)

Ryde, G. C., Booth, J. N., Brooks, N. E., Chesham, R. A., Moran, C. N., Gorely, T. (2018) The Daily Mile: What factors are associated with its implementation success? PLoS ONE, 13, (doi: 10.1371/journal.pone.0204988)

Rush, C. J., Campbell, R. T., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2018) Association is not causation: treatment effects cannot be estimated from observational data in heart failure. European Heart Journal, 39, pp. 3417-3438. (doi: 10.1093/eurheartj/ehy407)

Tofte, N. et al. (2018) Characteristics of high- and low-risk individuals in the PRIORITY study: urinary proteomics and mineralocorticoid receptor antagonism for prevention of diabetic nephropathy in Type 2 diabetes. Diabetic Medicine, 35, pp. 1375-1382. (doi: 10.1111/dme.13669)

Dayan, N., Schlosser, K., Stewart, D. J., Delles, C., Kaur, A., Pilote, L. (2018) Circulating microRNAs implicate multiple atherogenic abnormalities in the long-term cardiovascular sequelae of preeclampsia. American Journal of Hypertension, 31, pp. 1093-1097. (doi: 10.1093/ajh/hpy069)

Shah, S. J. et al. (2018) One-year safety and clinical outcomes of a transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction in the reduce elevated left atrial pressure in patients with heart failure (REDUCE LAP-HF I) trial: a randomized clinical trial. JAMA Cardiology, 3, pp. 968-977. (doi: 10.1001/jamacardio.2018.2936)

Ravassa, S., Trippel, T., Bach, D., Bachran, D., González, A., López, B., Wachter, R., Hasenfuss, G., Delles, C., Dominiczak, A. F., Pieske, B., Díez, J., Edelmann, F. (2018) Biomarker-based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo-DHF trial. European Journal of Heart Failure, 20, pp. 1290-1299. (doi: 10.1002/ejhf.1194)

McDowell, K., Petrie, M. C., Raihan, N. A., Logue, J. (2018) Effects of intentional weight loss in patients with obesity and heart failure: a systematic review. Obesity Reviews, 19, pp. 1189-1204. (doi: 10.1111/obr.12707)

Carrick, D., Haig, C., Maznyczka, A. M., Carberry, J., Mangion, K., Ahmed, N., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Radjenovic, A., Welsh, P., Sattar, N., Wetherall, K., Oldroyd, K. G., Berry, C. (2018) Hypertension, microvascular pathology and prognosis after an acute myocardial infarction. Hypertension, 72, pp. 720-730. (doi: 10.1161/HYPERTENSIONAHA.117.10786)

McEntegart, M. B., Corcoran, D., Carrick, D., Clerfond, G., Sidik, N., Collison, D., Robertson, K. R., Shaukat, A., Watkins, S., Rocchicholi, P. R., Eteiba, H., Petrie, M. P., Lindsay, M. M., Oldroyd, K. G., Berry, C. (2018) Incidence of procedural myocardial infarction and cardiac magnetic resonance imaging-detected myocardial injury following percutaneous coronary intervention with rotational atherectomy. EuroIntervention, 14, pp. 819-823. (doi: 10.4244/EIJ-D-17-01077)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2018) Persistent iron within the infarct core after ST-segment elevation myocardial infarction: implications for left ventricular remodeling and health outcomes. JACC: Cardiovascular Imaging, 11, pp. 1248-1256. (doi: 10.1016/j.jcmg.2017.08.027)

Divorty, N., Milligan, G., Graham, D., Nicklin, S. A. (2018) The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice. American Journal of Hypertension, 31, pp. 1049-1058. (doi: 10.1093/ajh/hpy073)

Campbell, R. T., Petrie, M. C., Jackson, C. E., Jhund, P. S., Wright, A., Gardner, R. S., Sonecki, P., Pozzi, A., McSkimming, P., McConnachie, A., Finlay, F., Davidson, P., Denvir, M. A., Johnson, M. J., Hogg, K. J., McMurray, J. J.V. (2018) Which patients with heart failure should receive specialist palliative care? European Journal of Heart Failure, 20, pp. 1338-1347. (doi: 10.1002/ejhf.1240)

Gillis, K., Stevens, K. K., Bell, E., Patel, R. K., Jardine, A. G., Morris, S. T.W., Schneider, M. P., Delles, C., Mark, P. B. (2018) Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease. Clinical Kidney Journal, 11, pp. 532-539. (doi: 10.1093/ckj/sfx158)

Yew, S. N., Carrick, D., Corcoran, D., Ahmed, N., Carberry, J., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Oldroyd, K. G., Berry, C. (2018) Coronary thermodilution waveforms after acute reperfused ST‐segment–elevation myocardial infarction: relation to microvascular obstruction and prognosis. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.008957)

Wessler, J., Kaye, D., Gustafsson, F., Petrie, M. C., Hasenfuβ, G., Lam, C. S.P., Borlaug, B. A., Komtebedde, J., Feldman, T., Shah, S. J., Burkhoff, D. (2018) Impact of baseline hemodynamics on the effects of a transcatheter interatrial shunt device in heart failure with preserved ejection fraction. Circulation: Heart Failure, 11, (doi: 10.1161/CIRCHEARTFAILURE.117.004540)

Rajani, R. M., Quick, S., Ruigrok, S. R., Graham, D., Harris, S. E., Verhaaren, B. F.J., Fornage, M., Seshadri, S., Atanur, S. S., Dominiczak, A. F., Smith, C., Wardlaw, J. M., Williams, A. (2018) Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats. Science Translational Medicine, 10, (doi: 10.1126/scitranslmed.aam9507)

Morgan, H. L., Butler, E., Ritchie, S., Herse, F., Dechend, R., Beattie, E., McBride, M. W., Graham, D. (2018) Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats. Hypertension, 72, pp. 208-218. (doi: 10.1161/HYPERTENSIONAHA.118.10935)

De Lucca Camargo, L., Harvey, A. P., Rios, F. J., Tsiropoulou, S., Silva, R. D. N. d. O., Cao, Z., Graham, D., McMaster, C., Burchmore, R. J., Hartley, R. C., Bulleid, N., Montezano, A. C., Touyz, R. M. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72, pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824)

Bailey, E., McBride, M. W., McClure, J. D., Beattie, W., Graham, D., Dominiczak, A., Smith, C., Wardlaw, J. (2018) Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease. Clinical Science, 132, pp. 1315-1328. (doi: 10.1042/CS20171572)

Montezano, A. C., De Lucca Camargo, L., Persson, P., Rios, F. J., Harvey, A. P., Agnostopoulou, A., Palacios, R., Gandara, A. C. P., Alves-Lopes, R., Neves, K. B., Dulak-Lis, M., Holterman, C. E., Lagerblad de Oliveira, P., Graham, D., Kennedy, C., Touyz, R. M. (2018) NADPH oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.009388)

Rørth, R., Jhund, P. S., Mogensen, U. M., Kristensen, S. L., Petrie, M. C., Køber, L., McMurray, J. J.V. (2018) Risk of incident heart failure in patients with diabetes and asymptomatic left ventricular systolic dysfunction. Diabetes Care, 41, pp. 1285-1291. (doi: 10.2337/dc17-2583)

Sliwa, K., Petrie, M. C., Hilfiker-Kleiner, D., Mebazaa, A., Jackson, A., Johnson, M. R., van der Meer, P., Mbakwem, A., Bauersachs, J. (2018) Long-term prognosis, subsequent pregnancy, contraception and overall management of peripartum cardiomyopathy: practical guidance paper from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European Journal of Heart Failure, 20, pp. 951-962. (doi: 10.1002/ejhf.1178)

Montezano, A. C., De Lucca Camargo, L., Persson, P., Rios, F., Harvey, A., Anagnostopoulou, A., Palacios, R., Gandara, A. C. P., Alves‐Lopes, R., Neves, K., Dulak‐Lis, M., Holterman, C. E., de Oliveira, P. L., Graham, D., Kennedy, C., Touyz, R. (2018) NADPH Oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.009388)

Perera, D., Clayton, T., Petrie, M. C., Greenwood, J. P., O'Kane, P. D., Evans, R., Sculpher, M., Mcdonagh, T., Gershlick, A., de Belder, M., Redwood, S., Carr-White, G., Marber, M. (2018) Percutaneous revascularization for ischemic ventricular dysfunction: rationale and design of the REVIVED-BCIS2 trial: percutaneous coronary intervention for ischemic cardiomyopathy. JACC: Heart Failure, 6, pp. 517-526. (doi: 10.1016/j.jchf.2018.01.024)

Moreton, F. C., Cullen, B., Delles, C., Santosh, C., Lopez Gonzalez, R., Dani, K., Muir, K. W. (2018) Vasoreactivity in CADASIL: comparison to structural MRI and neuropsychology. Journal of Cerebral Blood Flow and Metabolism, 38, pp. 1085-1095. (doi: 10.1177/0271678X17710375)

Chesham, R. A., Booth, J. N., Sweeney, E. L., Ryde, G. C., Gorely, T., Brooks, N. E., Moran, C. N. (2018) The Daily Mile makes primary school children more active, less sedentary and improves their fitness and body composition: a quasi-experimental pilot study. BMC Medicine, 16, (doi: 10.1186/s12916-018-1049-z)

Jackson, A. M., Dalzell, J. R., Walker, N. L., Coats, C. J., Jhund, P. S., Petrie, M. C. (2018) Peripartum cardiomyopathy: diagnosis and management. Heart, 104, pp. 779-786. (doi: 10.1136/heartjnl-2016-310599)

Seferović, P. M. et al. (2018) Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 20, pp. 853-872. (doi: 10.1002/ejhf.1170)

Lygirou, V., Latosinska, A., Makridakis, M., Mullen, W., Delles, C., Schanstra, J. P., Zoidakis, J., Pieske, B., Mischak, H., Vlahou, A. (2018) Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease. Journal of Translational Medicine, 16, (doi: 10.1186/s12967-018-1476-9)

Currie, G. E., von Scholten, B. J., Mary, S., Flores Guerrero, J.-L., Lindhardt, M., Reinhard, H., Jacobsen, P. K., Mullen, W., Parving, H.-H., Mischak, H., Rossing, P., Delles, C. (2018) Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria. Cardiovascular Diabetology, 17, (doi: 10.1186/s12933-018-0697-9)

Delles, C., Currie, G. (2018) Sex differences in hypertension and other cardiovascular diseases. Journal of Hypertension, 36, pp. 768-770. (doi: 10.1097/HJH.0000000000001655)

Petrie, M. C., Rocchiccioli, P. (2018) Coronary angiography in heart failure: when and why? Uncertainty reigns. Heart, 104, pp. 548-549. (doi: 10.1136/heartjnl-2017-312200)

Delles, C., Rankin, N. J., Boachie, C., McConnachie, A., Ford, I., Kangas, A., Soininen, P., Trompet, S., Mooijaart, S. P., Jukema, J. W., Zannad, F., Ala-Korpela, M., Salomaa, V., Havulinna, A. S., Welsh, P., Würtz, P., Sattar, N. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi: 10.1002/ejhf.1076)

Lee, M. M.Y. et al. (2018) Non-Invasive Versus Invasive Management in Patients With Prior Coronary Artery Bypass Surgery With a Non-ST Segment Elevation Acute Coronary Syndrome: Comparisons Between the Randomized Controlled Pilot Trial and Registry. (doi: 10.1016/S0735-1097(18)30586-2)

Feng, Y.-M., Thijs, L., Zhang, Z.-Y., Yang, W.-Y., Huang, Q.-F., Wei, F.-F., Kuznetsova, T., Jennings, A.-M., Delles, C., Lennox, R., Verhamme, P., Dominiczak, A., Staessen, J. A. (2018) Glomerular function in relation to circulating adhesion molecules and inflammation markers in a general population. Nephrology Dialysis Transplantation, 33, pp. 426-435. (doi: 10.1093/ndt/gfx256)

Stewart, R. A.H., Szalewska, D., Stebbins, A., Al-Khalidi, H. R., Cleland, J. G.H., Rynkiewicz, A., Drazner, M. H., White, H. D., Mark, D. B., Roy, A., Kosevic, D., Rajda, M., Jasinski, M., Leng, C. Y., Tungsubutra, W., Desvigne-Nickens, P., Velazquez, E. J., Petrie, M. C. (2018) Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy. Open Heart, 5, (doi: 10.1136/openhrt-2017-000752)

Petrie, M. C., Connelly, D. T., Gardner, R. S. (2018) Who needs an implantable cardioverter-defibrillator? Controversies and opportunities after DANISH. European Journal of Heart Failure, 20, pp. 413-416. (doi: 10.1002/ejhf.1135)

Velazquez, E. J., Petrie, M. C. (2018) CABG or PCI for diabetic patients with left ventricular dysfunction: closing in on the truth? Journal of the American College of Cardiology, 71, pp. 828-831. (doi: 10.1016/j.jacc.2018.01.014)

Chavan-Gautam, P., Rani, A., Freeman, D. J. (2018) Distribution of fatty acids and lipids during pregnancy. Elsevier

Currie, G., Delles, C. (2018) Blood pressure targets in the elderly. Journal of Hypertension, 36, pp. 234-236. (doi: 10.1097/HJH.0000000000001576)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Numé, A.-k., Gislason, G. H.,, Jhund, P. S., Petrie, M. C., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure. European Journal of Heart Failure, 20, pp. 240-247. (doi: 10.1002/ejhf.1046)

Feldman, T., Mauri, L., Kahwash, R., Litwin, S., Ricciardi, M. J., van der Harst, P., Penicka, M., Fail, P. S., Kaye, D. M., Petrie, M. C., Basuray, A., Hummel, S. L., Forde-McLean, R., Nielsen, C. D., Lilly, S., Massaro, J. M., Burkhoff, D., Shah, S. J. (2018) Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial. Circulation, 137, pp. 364-375. (doi: 10.1161/CIRCULATIONAHA.117.032094)

Onyiaodike, C. C., Murray, H. M., Zhang, R., Meyer, B. J., Jordan, F., Brown, E. A., Nibbs, R. J.B., Lyall, H., Sattar, N., Nelson, S. M., Freeman, D. J. (2018) Pre-conception maternal erythrocyte saturated to unsaturated fatty acid ratio predicts pregnancy after natural cycle frozen embryo transfer. Scientific Reports, 8, (doi: 10.1038/s41598-018-19500-0)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)

Lee, M. M.Y. et al. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial. (doi: 10.1136/heartjnl-2018-BCIS.9)

Rørth, R., Fosbøl, E. L., Kragholm, K., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study. Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795)

Bouabdallaoui, N. et al. (2018) Society of Thoracic Surgeons risk score and EuroSCORE-2 appropriately assess 30-day postoperative mortality in the STICH trial and a contemporary cohort of patients with left ventricular dysfunction undergoing surgical revascularization. Circulation: Heart Failure, 11, (doi: 10.1161/circheartfailure.118.005531)

Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)

2017

Hilfiker-Kleiner, D., Haghikia, A., Masuko, D., Nonhoff, J., Held, D., Libhaber, E., Petrie, M. C., Walker, N. L., Podewski, E., Berliner, D., Bauersachs, J., Sliwa, K. (2017) Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. European Journal of Heart Failure, 19, pp. 1723-1728. (doi: 10.1002/ejhf.808)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)

Krochmal, M., Kontostathi, G., Magalhães, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J.-L., Denis, C., Zoidakis, J., Zürbig, P., Delles, C., Schanstra, J. P., Mischak, H., Vlahou, A. (2017) Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy. Scientific Reports, 7, (doi: 10.1038/s41598-017-15359-9)

Mary, S., Kulkarni, M. J., Mehendale, S. S., Joshi, S. R., Giri, A. P. (2017) Differential accumulation of vimentin fragments in preeclamptic placenta. Cytoskeleton, 74, pp. 420-425. (doi: 10.1002/cm.21390)

Holman, R. R., Coleman, R. L., Chan, J. C. N., Chiasson, J.-L., Feng, H., Ge, J., Gerstein, H. C., Gray, R., Huo, Y., Lang, Z., McMurray, J. J., Rydén, L., Schröder, S., Sun, Y., Theodorakis, M. J., Tendera, M., Tucker, L., Tuomilehto, J., Wei, Y., Yang, W., Wang, D., Hu, D., Pan, C., ACE Study Group, (2017) Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5, pp. 877-886. (doi: 10.1016/S2213-8587(17)30309-1)

Wong, C. M., Hawkins, N. M., Ezekowitz, J. A., Jhund, P. S., Savu, A., MacDonald, M. R., Kristensen, S. L., Petrie, M. C., McMurray, J. J.V., McAlister, F. A., Kaul, P. (2017) Heart failure in young adults is associated with high mortality: a contemporary population-level analysis. Canadian Journal of Cardiology, 33, pp. 1472-1477. (doi: 10.1016/j.cjca.2017.05.009)

Pontillo, C. et al. (2017) Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker. Kidney International Reports, 2, pp. 1066-1075. (doi: 10.1016/j.ekir.2017.06.004)

Schmieder, R. E., Wagner, F., Mayr, M., Delles, C., Ott, C., Keicher, C., Hrabak-Paar, M., Heye, T., Aichner, S., Khder, Y., Yates, D., Albrecht, D., Langenickel, T., Freyhardt, P., Janka, R., Bremerich, J. (2017) The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study. European Heart Journal, 38, pp. 3308-3317. (doi: 10.1093/eurheartj/ehx525)

Kohli-Lynch, C.N., Boyd, K., Briggs, A., Delles, C. (2017) A Framework for the Cost-Effectiveness Analysis of Novel Biomarker Testing in Cardiovascular Disease. (doi: 10.1016/j.jval.2017.08.040)

Stevens, K., Denby, L., Patel, R. K., Mark, P. B., Kettlewell, S., Smith, G. L., Clancy, M. J., Delles, C., Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32, pp. 1617-1627. (doi: 10.1093/ndt/gfw252)

Jayabalan, N., Nair, S., Nuzhat, Z., Rice, G. E., Zúñiga, F. A., Sobrevia, L., Leiva, A., Sanhueza, C., Agustin Gutierrez, J., Lappas, M., Freeman, D. J., Salomon, C. (2017) Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes. Frontiers in Endocrinology, 8, (doi: 10.3389/fendo.2017.00239)

Sliwa, K., Mebazaa, A., Hilfiker-Kleiner, D., Petrie, M. C., Maggioni, A. P., Laroche, C., Regitz-Zagrosek, V., Schaufelberger, M., Tavazzi, L., van der Meer, P., Roos-Hesselink, J. W., Seferovic, P., van Spandonck-Zwarts, K., Mbakwem, A., Böhm, M., Mouquet, F., Pieske, B., Hall, R., Ponikowski, P., Bauersachs, J. (2017) Clinical characteristics of patients from the worldwide registry on peripartum cardiomyopathy (PPCM) European Journal of Heart Failure, 19, pp. 1131-1141. (doi: 10.1002/ejhf.780)

Bagot, C.N., Leishman, E., Onyiaodike, C.C., Jordan, F., Freeman, D.J. (2017) Normal pregnancy is associated with an increase in thrombin generation from the very early stages of the first trimester. Thrombosis Research, 157, pp. 49-54. (doi: 10.1016/j.thromres.2017.06.027)

Krochmal, M., Cisek, K., Filip, S., Markoska, K., Orange, C., Zoidakis, J., Gakiopoulou, C., Spasovski, G., Mischak, H., Delles, C., Vlahou, A., Jankowski, J. (2017) Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. Scientific Reports, 7, (doi: 10.1038/s41598-017-09393-w)

Gao, X., Salomon, C., Freeman, D. J. (2017) Extracellular vesicles from adipose tissue - a potential role in obesity and type 2 diabetes? Frontiers in Endocrinology, 8, (doi: 10.3389/fendo.2017.00202)

Bhat, S., Mary, S., Giri, A. P., Kulkarni, M. J. (2017) Advanced glycation end products (AGEs) in diabetic complications. Springer

Currie, G., Delles, C. (2017) Healthy vascular ageing. Hypertension, 70, pp. 229-231. (doi: 10.1161/HYPERTENSIONAHA.117.09122)

Small, H. Y., Cornelius, D. C., Guzik, T. J., Delles, C. (2017) Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy. Placenta, 56, pp. 59-64. (doi: 10.1016/j.placenta.2017.03.003)

Zhang, Z.‐Y., Ravassa, S., Nkuipou‐Kenfack, E., Yang, W.-Y., Kerr, S. M., Koeck, T., Campbell, A., Kuznetsova, T., Mischak, H., Padmanabhan, S., Dominiczak, A. F., Delles, C., Staessen, J. A. (2017) Novel urinary peptidomic classifier predicts incident heart failure. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.005432)

Gajjala, P. R., Jankowski, V., Heinze, G., Bilo, G., Zanchetti, A., Noels, H., Liehn, E., Perco, P., Schulz, A., Delles, C., Kork, F., Biessen, E., Narkiewicz, K., Kawecka-Jaszcz, K., Floege, J., Soranna, D., Zidek, W., Jankowski, J. (2017) Proteomic-biostatistic integrated approach for finding the underlying molecular determinants of hypertension in human plasma. Hypertension, 70, pp. 412-419. (doi: 10.1161/HYPERTENSIONAHA.116.08906)

Ryde, G. C., Gorely, T., Jepson, R., Gray, C., Shepherd, A., Mackison, D., Ireland, A. V., Williams, B., McMurdo, M. E.T., Evans, J. M.M. (2017) How active are women who play bingo: a cross-sectional study from the Well!Bingo project. BMC Women's Health, 17, (doi: 10.1186/s12905-017-0405-z)

Knez, J., Marrachelli, V. G., Cauwenberghs, N., Winckelmans, E., Zhang, Z., Thijs, L., Brguljan-Hitij, J., Plusquin, M., Delles, C., Monleon, D., Redón, J., Staessen, J. A., Nawrot, T. S., Kuznetsova, T. (2017) Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study. PLoS ONE, 12, (doi: 10.1371/journal.pone.0181036)

Shen, L., Jhund, P. S., Petrie, M. C., Claggett, B. L., Barlera, S., Cleland, J. G.F., Dargie, H. J., Granger, C. B., Kjekshus, J., Køber, L., Latini, R., Maggioni, A. P., Packer, M., Pitt, B., Solomon, S. D., Swedberg, K., Tavazzi, L., Wikstrand, J., Zannad, F., Zile, M. R., McMurray, J. J.V. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377, pp. 41-51. (doi: 10.1056/NEJMoa1609758)

Cleland, J. G.F., Pellicori, P., Clark, A. L., Petrie, M. C. (2017) Time to take the failure out of heart failure: the importance of optimism. JACC: Heart Failure, 5, pp. 538-540. (doi: 10.1016/j.jchf.2017.04.003)

Huda, S. S., Jordan, F., Bray, J., Love, G., Payne, R., Sattar, N., Freeman, D. J. (2017) Visceral adipose tissue activated macrophage content and inflammatory adipokine secretion is higher in pre-eclampsia than in healthy pregnancy. Clinical Science, 131, pp. 1529-1540. (doi: 10.1042/CS20160832)

Harvey, A. P., Montezano, A. C., Hood, K. Y., Lopes, R. A., Rios, F., Ceravolo, G., Graham, D., Touyz, R. M. (2017) Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis. Life Sciences, 179, pp. 110-119. (doi: 10.1016/j.lfs.2017.05.002)

Sattar, N., Petrie, M. C., Zinman, B., Januzzi Jr., J. L. (2017) Novel diabetes drugs and the cardiovascular specialist. Journal of the American College of Cardiology, 69, pp. 2646-2656. (doi: 10.1016/j.jacc.2017.04.014)

Neisius, U., Olson, E., Rossi, S. H., Ibrahim, H. A., Currie, G., Dominiczak, A., Delles, C. (2017) Evaluation of the systemic micro- and macrovasculature in stable angina: a case-control study. PLoS ONE, 12, (doi: 10.1371/journal.pone.0178412)

Packer, M., O'Connor, C., McMurray, J. J.V., Wittes, J., Abraham, W. T., Anker, S. D., Dickstein, K., Filippatos, G., Holcomb, R., Krum, H., Maggioni, A. P., Mebazaa, A., Peacock, W. F., Petrie, M. C., Ponikowski, P., Ruschitzka, F., van Veldhuisen, D. J., Kowarski, L. S., Schactman, M., Holzmeister, J. (2017) Effect of ularitide on cardiovascular mortality in acute heart failure. New England Journal of Medicine, 376, pp. 1956-1964. (doi: 10.1056/NEJMoa1601895)

Packer, M. et al. (2017) Long-term effect of endothelin receptor antagonism with bosentan on the morbidity and mortality of patients with severe chronic heart failure : primary results of the ENABLE Trials. JACC: Heart Failure, 5, pp. 317-326. (doi: 10.1016/j.jchf.2017.02.021)

Meyer, B. J., Freeman, D. J. (2017) Maternal plasma docosahexaenoic acid (DHA) concentrations increase at the critical time of neural tube closure. Fats of Life,

Mary, S., Small, H. Y., Siwy, J., Mullen, W., Giri, A., Delles, C. (2017) Polymerization-incompetent uromodulin in the pregnant stroke-prone spontaneously hypertensive rat. Hypertension, 69, pp. 910-918. (doi: 10.1161/HYPERTENSIONAHA.116.08826)

Jacobs, L., Efremov, L., Ferreira, J. P., Thijis, L., Yang, W.-Y., Zhang, Z.-Y., Latini, R., Masson, S., Agabiti, N., Sever, P., Delles, C., Sattar, N., Butler, J., Cleland, J., Kuznetsova, T., Staessen, J. A., Zannad, F. (2017) Risk for incident heart failure: a subject-level meta-analysis from the Heart “OMics” in AGEing (HOMAGE) study. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.005231)

Dominiczak, A., Delles, C., Padmanabhan, S. (2017) Genomics and precision medicine for clinicians and scientists in hypertension. Hypertension, 69, pp. e10-e13. (doi: 10.1161/HYPERTENSIONAHA.116.08252)

Layland, J. J., Carberry, J., May, V. T.Y., Lee, M., Eteiba, H., Lindsay, M., Petrie, M., McEntegart, M., Watkins, S., Shaukat, A., Oldroyd, K., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Hannah, A., Stewart, A., Henderson, R., McConnachie, A., Berry, C. (2017) Decision Making Using Fractional Flow Reserve is Associated With Lower Rates of Incomplete Revascularization Compared With Angiographic Guided Decision Making Amongst Patients With NSTEMI. (doi: 10.1016/s0735-1097(17)34446-7)

Mary, S., Kulkarni, M. J., Mehendale, S. S., Joshi, S. R., Giri, A. P. (2017) Tubulointerstitial nephritis antigen-like 1 protein is downregulated in the placenta of pre-eclamptic women. Clinical Proteomics, 14, (doi: 10.1186/s12014-017-9144-2)

Htun, N. M., Magliano, D. J., Zhang, Z.-Y., Lyons, J., Petit, T., Nkuipou-Kenfack, E., Ramirez-Torres, A., von zur Muhlen, C., Maahs, D., Schanstra, J. P., Pontillo, C., Pejchinovski, M., Snell-Bergeon, J. K., Delles, C., Mischak, H., Staessen, J. A., Shaw, J. E., Koeck, T., Peter, K. (2017) Prediction of acute coronary syndromes by urinary proteome analysis. PLoS ONE, 12, (doi: 10.1371/journal.pone.0172036)

Small, H. Y., Akehurst, C., Sharafetdinova, L., McBride, M. W., McClure, J. D., Robinson, S. W., Carty, D. M., Freeman, D. J., Delles, C. (2017) HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia. Physiological Genomics, 49, pp. 193-200. (doi: 10.1152/physiolgenomics.00106.2016)

Currie, G., Delles, C. (2017) The future of "omics" in hypertension. Canadian Journal of Cardiology, 33, pp. 601-610. (doi: 10.1016/j.cjca.2016.11.023)

Carty, D. M., Doogan, F., Welsh, P., Dominiczak, A. F., Delles, C. (2017) Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, pp. 366-369. (doi: 10.1016/j.ejogrb.2017.01.048)

Mary, S., Kulkarni, M. J., Malakar, D., Joshi, S. R., Mehendale, S. S., Giri, A. P. (2017) Placental proteomics provides insights into pathophysiology of pre-eclampsia and predicts possible markers in plasma. Journal of Proteome Research, 16, pp. 1050-1060. (doi: 10.1021/acs.jproteome.6b00955)

Docherty, K. F., Campbell, R. T., Jhund, P., Petrie, M. C., McMurray, J. J.V. (2017) How robust are clinical trials in heart failure? European Heart Journal, 38, pp. 338-345. (doi: 10.1093/eurheartj/ehw427)

Freeman, D. J., Meyer, B. J. (2017) Brain food for babies. Biochemist, 39, pp. 26-29.

Koh-Tan, H.H. C., Dashti, M., Wang, T., Beattie, W., Mcclure, J., Young, B., Dominiczak, A. F., McBride, M. W., Graham, D. (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35, pp. 319-329. (doi: 10.1097/HJH.0000000000001155)

Delles, C., Husi, H. (2017) Systems biology approach in hypertension research. Springer

Mancini, S. J., White, A. D., Bijland, S., Rutherford, C., Graham, D., Richter, E. A., Viollet, B., Touyz, R. M., Palmer, T. M., Salt, I. P. (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010)

Kristensen, S. L., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Preiss, D., Win, S., Køber, L., McKelvie, R. S., Zile, M. R., Anand, I. S., Komajda, M., Gottdiener, J. S., Carson, P. E., McMurray, J. J.V. (2017) Clinical and echocardiographic characteristics and cardiovascular outcomes according to diabetes status in patients with heart failure and preserved ejection fraction. A report from the Irbesartan in Heart Failure with Preserved Ejection Fraction Trial (I-Preserve) Circulation, 135, pp. 724-735. (doi: 10.1161/CIRCULATIONAHA.116.024593)

Delles, C., Vanholder, R. (2017) Chronic kidney disease. Clinical Science, 131, pp. 225-226. (doi: 10.1042/CS20160624)

Ryde, G., Brown, H. E. (2017) Physical activity and workplace wellbeing. Routledge

2016

Carrick, D., Haig, C., Ahmed, N., Carberry, J., Teng Yue May, V., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davies, A., Abouzaid, A. M., Mordi, I., Ford, I., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment elevation myocardial infarction. Circulation, 134, pp. 1833-1847. (doi: 10.1161/CIRCULATIONAHA.116.022603)

Kaye, D. M., Hasenfuß, G., Neuzil, P., Post, M. C., Doughty, R., Trochu, J.-N., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Walton, A., Muller, D., Walters, D., Hausleiter, J., Raake, P., Petrie, M. C., Bergmann, M., Jondeau, G., Feldman, T., van Veldhuisen, D. J., Ponikowski, P., Silvestry, F. E., Burkhoff, D., Hayward, C. (2016) One-year outcomes after transcatheter insertion of an interatrial shunt device for the management of heart failure with preserved ejection fraction. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003662)

Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J.V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Rocca, H. P. B.-L., Delles, C., Heymans, S., Sattar, N., Jukema, J. W., Cleland, J. G.F., Zannad, F., Rossignol, P. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, (doi: 10.1186/s12916-016-0731-2)

Gilson, N. D., Ng, N., Pavey, T. G., Ryde, G. C., Straker, L., Brown, W. J. (2016) Project Energise: Using participatory approaches and real time computer prompts to reduce occupational sitting and increase work time physical activity in office workers. Journal of Science and Medicine in Sport, 19, pp. 926-930. (doi: 10.1016/j.jsams.2016.01.009)

Rutherford, C., Speirs, C., Williams, J. J.L., Ewart, M.-A., Mancini, S. J., Hawley, S. A., Delles, C., Viollet, B., Costa-Pereira, A. P., Baillie, G. S., Salt, I. P., Palmer, T. M. (2016) Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. Science Signaling, 9, (doi: 10.1126/scisignal.aaf8566)

Petrie, M. C., Jhund, P. S., She, L., Adlbrecht, C., Doenst, T., Panza, J. A., Hill, J. A., Lee, K. L., Rouleau, J. L., Prior, D. L., Ali, I. S., Maddury, J., Golba, K. S., White, H. D., Carson, P., Chrzanowski, L., Romanov, A., Miller, A. B., Velazquez, E. J. (2016) Ten-year outcomes after coronary artery bypass grafting according to age in patients with heart failure and left ventricular systolic dysfunction: an analysis of the extended follow-up of the STICH Trial (Surgical Treatment for Ischemic Heart Failure) Circulation, 134, pp. 1314-1324. (doi: 10.1161/CIRCULATIONAHA.116.024800)

Hennigan, B., Oldroyd, K. G., Berry, C., Johnson, N., McClure, J., McCartney, P., McEntegart, M. B., Eteiba, H., Petrie, M. C., Rocchiccioli, P., Good, R., Lindsay, M. M., Hood, S., Watkins, S. (2016) Discordance between resting and hyperemic indices of coronary stenosis severity: the VERIFY 2 study (a comparative study of resting coronary pressure gradient, instantaneous wave-free ratio and fractional flow reserve in an unselected population referred for invasive angiography) Circulation: Cardiovascular Interventions, 9, (doi: 10.1161/CIRCINTERVENTIONS.116.004016)

Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D., Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68, pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933)

Currie, G., Delles, C. (2016) Urinary proteomics for diagnosis and monitoring of diabetic nephropathy. Current Diabetes Reports, 16, (doi: 10.1007/s11892-016-0798-3)

Rørth, R., Wong, C., Kragholm, K., Fosbøl, E. L., Mogensen, U. M., Lamberts, M., Petrie, M. C., Jhund, P. S., Gerds, T. A., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2016) Return to the workforce following first hospitalization for heart failure: a Danish nationwide cohort study. Circulation, 134, pp. 999-1009. (doi: 10.1161/CIRCULATIONAHA.116.021859)

Brown, S. H.J., Eather, S. R., Freeman, D. J., Meyer, B. J., Mitchell, T. W. (2016) A lipidomic analysis of placenta in preeclampsia: evidence for lipid storage. PLoS ONE, 11, (doi: 10.1371/journal.pone.0163972)

Currie, G., Matt, P., Delles, C. (2016) Clinical cardiovascular proteomics. Springer

Currie, G., Taylor, A. H.M., Fujita, T., Ohtsu, H., Lindhart, M., Rossing, P., Boesby, L., Edwards, N. C., Ferro, C. J., Townend, J. N., van den Meiracker, A. H., Saklayen, M. G., Oveisi, S., Jardine, A. G., Delles, C., Preiss, D. J., Mark, P. B. (2016) Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis. BMC Nephrology, 17, (doi: 10.1186/s12882-016-0337-0)

Bauersachs, J., Arrigo, M., Hilfiker-Kleiner, D., Veltmann, C., Coats, A. J.S., Crespo-Leiro, M. G., De Boer, R. A., van der Meer, P., Maack, C., Mouquet, F., Petrie, M. C., Piepoli, M. F., Regitz-Zagrosek, V., Schaufelberger, M., Seferovic, P., Tavazzi, L., Ruschitzka, F., Mebazaa, A., Sliwa, K. (2016) Current management of patients with severe acute peripartum cardiomyopathy: practical guidance from the Heart Failure Association of the European Society of Cardiology Study Group on peripartum cardiomyopathy. European Journal of Heart Failure, 18, pp. 1096-1105. (doi: 10.1002/ejhf.586)

Hawkins, N. M., Jhund, P. S., Pozzi, A., O'Meara, E., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., Petrie, M. C., Virani, S., McMurray, J. J.V. (2016) Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non-vitamin K antagonist oral anticoagulant dose adjustment. European Journal of Heart Failure, 18, pp. 1162-1171. (doi: 10.1002/ejhf.614)

Morgan, H., Small, H.Y., Beattie, E., McBride, M.W., Graham, D. (2016) [OP.5D.02] Transcriptomic changes in early pregnancy-associated uterine artery remodelling in stroke prone spontaneously hypertensive rat. Journal of Hypertension, 34, pp. e63-e63. (doi: 10.1097/01.hjh.0000491501.79443.05)

Carberry, J., Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Remote zone extracellular volume and left ventricular remodeling in survivors of st-elevation myocardial infarction. Hypertension, 68, pp. 385-391. (doi: 10.1161/HYPERTENSIONAHA.116.07222)

Mordi, I., Mordi, N., Delles, C., Tzemos, N. (2016) Endothelial dysfunction in human essential hypertension. Journal of Hypertension, 34, pp. 1464-1472. (doi: 10.1097/hjh.0000000000000965)

Wanner, C., Inzucchi, S. E., Lachin, J. M., Fitchett, D., von Eynatten, M., Mattheus, M., Johansen, O. E., Woerle, H. J., Broedl, U. C., Zinman, B., EMPA-REG OUTCOME Investigators, (2016) Empagliflozin and progression of kidney disease in type 2 diabetes. New England Journal of Medicine, 375, pp. 323-334. (doi: 10.1056/NEJMoa1515920)

Currie, G., Delles, C. (2016) Use of biomarkers in the evaluation and treatment of hypertensive patients. Current Hypertension Reports, 18, (doi: 10.1007/s11906-016-0661-6)

Carrick, D., Haig, C., Carberry, J., Teng Tue May, V., Mccartney, P., Welsh, P., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Mahrous, A., Rauhalammi, S. M.O., Mordi, I., Ford, I., Radjenovic, A., Sattar, N., Oldroyd, K. G., Berry, C. (2016) Microvascular resistance of the culprit coronary artery in acute ST-elevation myocardial infarction. JCI Insight, 1, (doi: 10.1172/jci.insight.85768)

Campbell, R. T., Willox, G. P., Jhund, P. S., Hawkins, N. M., Huang, F., Petrie, M. C., McMurray, J. J. V. (2016) Reporting of lost to follow-up and treatment discontinuation in device and pharmacotherapy trials in chronic heart failure: a systematic review. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.115.002842)

Velazquez, E. J., Lee, K. L., Jones, R. H., Al-Khalidi, H. R., Hill, J. A., Panza, J. A., Michler, R. E., Bonow, R. O., Doenst, T., Petrie, M. C., Oh, J. K., She, L., Moore, V. L., Desvigne-Nickens, P., Sopko, G., Rouleau, J. L. (2016) Coronary-artery bypass surgery in patients with ischemic cardiomyopathy. New England Journal of Medicine, 374, pp. 1511-1520. (doi: 10.1056/NEJMoa1602001)

Lee, M. M.Y., Petrie, M. C., Rocchiccioli, P., Simpson, J., Jackson, C., Brown, A., Corcoran, D., Mangion, K., McEntegart, M., Shaukat, A., Rae, A., Hood, S., Peat, E., Findlay, I., Murphy, C., Cormack, A., Bukov, N., Balachandran, K., Papworth, R., Ford, I., Briggs, A., Berry, C. (2016) Non-invasive versus invasive management in patients with prior coronary artery bypass surgery with a non-ST segment elevation acute coronary syndrome: study design of the pilot randomised controlled trial and registry (CABG-ACS) Open Heart, 3, (doi: 10.1136/openhrt-2015-000371)

Abdul-Rahim, A. H., MacIsaac, R. L., Jhund, P. S., Petrie, M. C., Lees, K. R., McMurray, J. J.V. (2016) Efficacy and safety of digoxin in patients with heart failure and reduced ejection fraction according to diabetes status: An analysis of the Digitalis Investigation Group (DIG) trial. International Journal of Cardiology, 209, pp. 310-316. (doi: 10.1016/j.ijcard.2016.02.074)

Wan Sulaiman, W.N., Caslake, M.J., Delles, C., Karlsson, H., Mulder, M.T., Graham, D., Freeman, D.J. (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130, pp. 491-497. (doi: 10.1042/cs20150475)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Lindsay, M., Mahrous, A., Ford, I., Tzemos, N., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Prognostic significance of infarct core pathology revealed by quantitative non-contrast in comparison to contrast cardiac magnetic resonance imaging in reperfused ST-elevation myocardial infarction survivors. European Heart Journal, 37, pp. 1044-1059. (doi: 10.1093/eurheartj/ehv372)

Eisele, N., Albrecht, C., Mistry, H. D., Dick, B., Baumann, M., Surbek, D., Currie, G., Delles, C., Mohaupt, M. G., Escher, G., Gennari-Moser, C. (2016) Placental expression of the angiogenic placental growth factor is stimulated by both aldosterone and simulated starvation. Placenta, 40, pp. 18-24. (doi: 10.1016/j.placenta.2016.02.004)

Neisius, U., Koeck, T., Mischak, H., Rossi, S. H., Olson, E., Carty, D. M., Dymott, J. A., Dominiczak, A. F., Berry, C., Oldroyd, K. G., Delles, C. (2016) Urine proteomics in the diagnosis of stable angina. BMC Cardiovascular Disorders, 16, (doi: 10.1186/s12872-016-0246-y)

Hasenfuß, G., Hayward, C., Burkhoff, D., Silvestry, F. E., McKenzie, S., Gustafsson, F., Malek, F., Van der Heyden, J., Lang, I., Petrie, M. C., Cleland, J. G.F., Leon, M., Kaye, D. M. (2016) A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial. Lancet, 387, pp. 1298-1304. (doi: 10.1016/S0140-6736(16)00704-2)

Mullan, A., Delles, C., Ferrell, W., Mullen, W., Edwards, C. A., McColl, J. H., Roberts, S. A., Lean, M. (2016) Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized trial. Atherosclerosis, 246, pp. 169-176. (doi: 10.1016/j.atherosclerosis.2016.01.004)

Currie, G., Delles, C., Touyz, R. M., Staessen, J. A., Dominiczak, A. F., Jennings, G. L. R., Wang, J.-G. (2016) A woman with treatment-resistant hypertension. Hypertension, 67, pp. 243-250. (doi: 10.1161/HYPERTENSIONAHA.115.06756)

Small, H. Y., Currie, G. E., Delles, C. (2016) Prostasin, proteases, and preeclampsia. Journal of Hypertension, 34, pp. 193-195. (doi: 10.1097/hjh.0000000000000828)

Carrick, D., Haig, C., Rauhalammi, S., Clerfond, G., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Mahrous, A., Welsh, P., Sattar, N., Ford, I., Oldroyd, K., Radjenovic, A., Berry, C. (2016) Temporal evolution of myocardial hemorrhage and edema in patients after acute ST-elevation myocardial infarction: pathophysiologic insights and clinical implications. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.115.002834)

Ahmed, N., Layland, J., Carrick, D., Petrie, M. C., McEntegart, M., Eteiba, H., Hood, S., Lindsay, M., Watkins, S., Davie, A., Mahrous, A., Carberry, J., Teng, V., McConnachie, A., Curzen, N., Oldroyd, K. G., Berry, C. (2016) Safety of guidewire-based measurement of fractional flow reserve and the index of microvascular resistance using intravenous adenosine in patients with acute or recent myocardial infarction. International Journal of Cardiology, 202, pp. 305-310. (doi: 10.1016/j.ijcard.2015.09.014)

Small, H. Y., Morgan, H., Beattie, E., Griffin, S., Indahl, M., Delles, C., Graham, D. (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022)

Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G.F., Coats, A. J.S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., Jessup, M., Linde, C., Nihoyannopoulos, P., Parissis, J. T., Pieske, B., Riley, J. P., Rosano, G. M.C., Ruilope, L. M., Ruschitzka, F., Rutten, F. H., van der Meer, P., McMurray, J. J.V., Petrie, M. C. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 37, pp. 2129-2200. (doi: 10.1093/eurheartj/ehw128)

Olsen, M. H., Angell, S. Y., Asma, S., Boutouyrie, P., Burger, D., Chirinos, J. A., Damasceno, A., Delles, C., Gimenez-Roqueplo, A.-P., Hering, D., López-Jaramillo, P., Martinez, F., Perkovic, V., Rietzschel, E. R., Schillaci, G., Schutte, A. E., Scuteri, A., Sharman, J. E., Wachtell, K., Wang, J. G. (2016) A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension. Lancet, 388, pp. 2665-2712. (doi: 10.1016/S0140-6736(16)31134-5)

Zhang, Z.-y., Ravassa, S., Yang, W.-Y., Petit, T., Pejchinovski, M., Zürbig, P., López, B., Wei, F.-F., Pontillo, C., Thijs, L., Jacobs, L., González, A., Koeck, T., Delles, C., Voigt, J.-U., Verhamme, P., Kuznetsova, T., Díez, J., Mischak, H., Staessen, J. A. (2016) Diastolic left ventricular function in relation to urinary and serum collagen biomarkers in a general population. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167582)

Stirrat, C. t., Alam, S. R., MacGillivray, T. J., Gray, C. D., Forsythe, R., Dweck, M. R., Payne, J. R., Prasad, S. K., Petrie, M. C., Gardner, R. S., Mirsadraee, S., Henriksen, P. A., Newby, D. E., Semple, S. I.K. (2016) Ferumoxytol-enhanced magnetic resonance imaging methodology and normal values at 1.5 and 3T. Journal of Cardiovascular Magnetic Resonance, 18, (doi: 10.1186/s12968-016-0261-2)

McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C., Milligan, G., Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52, pp. 383-395. (doi: 10.1159/000444754)

Mangion, K., Carrick, D., Hennigan, B. W., Payne, A. R., McClure, J., Mason, M., Das, R., Wilson, R., Edwards, R. J., Petrie, M. C., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2016) Infarct size and left ventricular remodelling after preventive percutaneous coronary intervention. Heart, 102, pp. 1980-1987. (doi: 10.1136/heartjnl-2015-308660)

Meyer, B. J., Onyiaodike, C. C., Brown, E. A., Jordan, F., Murray, H., Nibbs, R. J. B., Sattar, N., Lyall, H., Nelson, S. M., Freeman, D. J. (2016) Maternal plasma DHA levels increase prior to 29 days post-LH surge in women undergoing frozen embryo transfer: a prospective, observational study of human pregnancy. Journal of Clinical Endocrinology and Metabolism, 101, pp. 1745-1753. (doi: 10.1210/jc.2015-3089)

Carrick, D., Haig, C., Watkins, S., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Davie, A., Mahrous, A., Mordi, I., Rauhalammi, S., Sattar, N., Welsh, P., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/CIRCIMAGING.115.004148)

Gillis, K. A., Mccomb, C., Patel, R. K., Stevens, K. K., Schneider, M. P., Radjenovic, A., Morris, S. T.W., Roditi, G. H., Delles, C., Mark, P. B. (2016) Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease. Nephron, 133, pp. 183-192. (doi: 10.1159/000447601)

Lindhardt, M., Persson, F., Currie, G., Pontillo, C., Beige, J., Delles, C., von der Leyen, H., Mischak, H., Navis, G., Noutsou, M., Ortiz, A., Ruggenenti, P. L., Rychlik, I., Spasovski, G., Rossing, P. (2016) Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial. BMJ Open, 6, (doi: 10.1136/bmjopen-2015-010310)

Sheikh, A. M., Small, H. Y., Currie, G., Delles, C. (2016) Systematic review of micro-RNA expression in pre-eclampsia identifies a number of common pathways associated with the disease. PLoS ONE, 11, (doi: 10.1371/journal.pone.0160808)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., Anker, S. D., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J. V. (2016) The incremental prognostic and clinical value of multiple novel biomarkers in heart failure. European Journal of Heart Failure, 18, pp. 1491-1498. (doi: 10.1002/ejhf.543)

2015

Nam, J., Briggs, A., Layland, J., Oldroyd, K. G., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Eteiba, H., Petrie, M. C., Lindsay, M., Watkins, S., Corbett, S., O'Rourke, B., O'Donnell, A., Stewart, A., Hannah, A., McConnachie, A., Henderson, R., Berry, C. (2015) Fractional flow reserve (FFR) versus angiography in guiding management to optimise outcomes in non-ST segment elevation myocardial infarction (FAMOUS-NSTEMI) developmental trial: cost-effectiveness using a mixed trial- and model-based methods. Cost Effectiveness and Resource Allocation, 2015, (doi: 10.1186/s12962-015-0045-9)

Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., Broedl, U. C., Inzucchi, S. E., EMPA-REG OUTCOME Investigators, (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. New England Journal of Medicine, 373, pp. 2117-2128. (doi: 10.1056/NEJMoa1504720)

Jolicœur, E. M., Dunning, A., Castelvecchio, S., Dabrowski, R., Waclawiw, M. A., Petrie, M. C., Stewart, R., Jhund, P. S., Desvigne-Nickens, P., Panza, J. A., Bonow, R. O., Sun, B., San, T. R., Al-Khalidi, H. R., Rouleau, J. L., Velazquez, E. J., Cleland, J. G.F. (2015) Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction. Journal of the American College of Cardiology, 66, pp. 2092-2100. (doi: 10.1016/j.jacc.2015.08.882)

Simpson, J., Castagno, D., Doughty, R. N., Poppe, K. K., Earle, N., Squire, I., Richards, M., Andersson, B., Ezekowitz, J. A., Komajda, M., Petrie, M. C., McAlister, F. A., Gamble, G. D., Whalley, G. A., McMurray, J. J.V. (2015) Is heart rate a risk marker in patients with chronic heart failure and concomitant atrial fibrillation? Results from the MAGGIC meta-analysis. European Journal of Heart Failure, 17, pp. 1182-1191. (doi: 10.1002/ejhf.346)

Akehurst, C., Small, H., Sharafetdinova, L., Forrest, R., Beattie, W., Brown, C. E., Robinson, S. W., McClure, J. D., Work, L. M., Carty, D. M., McBride, M. W., Freeman, D. J., Delles, C. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33, pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656)

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892)

Lindsey, M. L., Mayr, M., Gomes, A. V., Delles, C., Arrell, D. K., Murphy, A. M., Lange, R. A., Costello, C. E., Jin, Y.-F., Laskowitz, D. T., Sam, F., Terzic, A., Van Eyk, J., Srinivas, P. R. (2015) Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association. Circulation, 132, pp. 852-872. (doi: 10.1161/CIR.0000000000000226)

Fisher, M., Petrie, M., Ambery, P., Donaldson, J., McMurray, J. J.V., Ye, J. (2015) Cardiovascular safety of albiglutide in the Harmony programme: a meta-analysis. Lancet Diabetes and Endocrinology, 3, pp. 697-703. (doi: 10.1016/s2213-8587(15)00233-8)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., McInnes, I. B., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J.V. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3, pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014)

Schanstra, J.P. et al. (2015) Diagnosis and prediction of CKD progression by assessment of urinary peptides. Journal of the American Society of Nephrology, 26, pp. 1999-2010. (doi: 10.1681/asn.2014050423)

Rush, C. J., Campbell, R. T., Jhund, P. S., Connolly, E. C., Preiss, D., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Falling cardiovascular mortality in heart failure with reduced ejection fraction and implications for clinical trials. JACC: Heart Failure, 3, pp. 603-614. (doi: 10.1016/j.jchf.2015.03.013)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544)

MacDonald, M. R., She, L., Doenst, T., Binkley, P. F., Rouleau, J. L., Tan, R.-S., Lee, K. L., Miller, A. B., Sopko, G., Szalewska, D., Waclawiw, M. A., Dabrowski, R., Castelvecchio, S., Adlbrecht, C., Michler, R. E., Oh, J. K., Velazquez, E. J., Petrie, M. C. (2015) Clinical characteristics and outcomes of patients with and without diabetes in the Surgical Treatment for Ischemic Heart Failure (STICH) trial. European Journal of Heart Failure, 17, pp. 725-734. (doi: 10.1002/ejhf.288)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Lindsay, M., Watkins, S., Hood, S., Davie, A., Marous, A., Sattar, N., Welsh, P., Tzemos, N., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2015) Pathophysiology of LV remodeling in survivors of STEMI : inflammation, remote myocardium, and prognosis. JACC: Cardiovascular Imaging, 8, pp. 779-789. (doi: 10.1016/j.jcmg.2015.03.007)

Petrie, M.C., Boyle, J.G., McKay, G.A. (2015) Use of metformin in chronic kidney disease should continue to be based on common sense in the absence of an evidence base. Diabetic Medicine, 32, pp. 981-982. (doi: 10.1111/dme.12709)

Al Halabi, S., Qintar, M., Hussein, A., Alraies, M. C., Jones, D. G., Wong, T., MacDonald, M. R., Petrie, M. C., Cantillon, D., Tarakji, K. G., Kanj, M., Bhargava, M., Varma, N., Baranowski, B., Wilkoff, B. L., Wazni, O., Callahan, T., Saliba, W., Chung, M. K. (2015) Catheter ablation for atrial fibrillation in heart failure patients. JACC: Clinical Electrophysiology, 1, pp. 200-209. (doi: 10.1016/j.jacep.2015.02.018)

Dalzell, J. R., Rocchiccioli, J. P., Weir, R. A.P., Jackson, C. E., Padmanabhan, N., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) The emerging potential of the apelin-APJ system in heart failure. Journal of Cardiac Failure, 21, pp. 489-498. (doi: 10.1016/j.cardfail.2015.03.007)

Dakin, R. S., Parker, A. L., Delles, C., Nicklin, S. A., Baker, A. H. (2015) Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector. Human Gene Therapy, 26, pp. 312-319. (doi: 10.1089/hum.2015.019)

Fox, C. S., Hall, J. L., Arnett, D. K., Ashley, E. A., Delles, C., Engler, M. B., Freeman, M. W., Johnson, J. A., Lanfear, D. E., Liggett, S. B., Lusis, A. J., Loscalzo, J., MacRae, C. A., Musunuru, K., Newby, L. K., O'Donnell, C. J., Rich, S. S., Terzic, A. (2015) Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation, 131, pp. 1715-1736. (doi: 10.1161/CIR.0000000000000211)

Kukulski, T., She, L., Racine, N., Gradinac, S., Panza, J. A., Velazquez, E. J., Chan, K., Petrie, M. C., Lee, K. L., Pellikka, P. A., Romanov, A., Biernat, J., Rouleau, J. L., Batlle, C., Rogowski, J., Ferrazzi, P., Zembala, M., Oh, J. K. (2015) Implication of right ventricular dysfunction on long-term outcome in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting with or without surgical ventricular reconstruction. Journal of Thoracic and Cardiovascular Surgery, 149, pp. 1312-1321. (doi: 10.1016/j.jtcvs.2014.09.117)

Ravassa, S., Kuznetsova, T., Varo, N., Thijs, L., Delles, C., Dominiczak, A., Díez, J., Staessen, J. A. (2015) Biomarkers of cardiomyocyte injury and stress identify left atrial and left ventricular remodelling and dysfunction: a population-based study. International Journal of Cardiology, 185, pp. 177-185. (doi: 10.1016/j.ijcard.2015.03.046)

Rousset, C. I., Leiper, F. C., Kichev, A., Gressens, P., Carling, D., Hagberg, H., Thornton, C. (2015) A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice. Journal of Neurochemistry, 133, pp. 242-252. (doi: 10.1111/jnc.13034)

McInnes, I. B., Thompson, L., Giles, J. T., Bathon, J. M., Salmon, J. E., Beaulieu, A. D., Codding, C. E., Carlson, T. H., Delles, C., Lee, J. S., Sattar, N. (2015) Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study. Annals of the Rheumatic Diseases, 74, pp. 694-702. (doi: 10.1136/annrheumdis-2013-204345)

Mischak, H., Delles, C., Vlahou, A., Vanholder, R. (2015) Proteomic biomarkers in kidney disease: issues in development and implementation. Nature Reviews Nephrology, 11, pp. 221-232. (doi: 10.1038/nrneph.2014.247)

Skogstrand, T., Leh, S., McClure, J., Dashti, M., Iversen, B. M., Graham, D., McBride, M., Hultström, M. (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33, pp. 584-596. (doi: 10.1097/HJH.0000000000000395)

Campbell, R. T., Jackson, C., Wright, A., Gardner, R. S., Ford, I., Davidson, P. M., Denvir, M. A., Hogg, K. J., Johnson, M. J., Petrie, M. C., McMurray, J. J. V. (2015) Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design. ESC Heart Failure, 2, pp. 25-36. (doi: 10.1002/ehf2.12027)

Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Brunton, A. P.T., Jhund, P. S., Wong, C. M., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with angina and heart failure in the CHARM (Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity) programme. European Journal of Heart Failure, 17, pp. 196-204. (doi: 10.1002/ejhf.221)

Layland, J., Rauhalammi, S., Watkins, S., Ahmed, N., McClure, J., Lee, M. M.Y., Carrick, D., O’Donnell, A., Sood, A., Petrie, M. C., Teng Yue May, V., Eteiba, H., Lindsay, M., McEntegart, M., Oldroyd, K. G., Radjenovic, A., Berry, C. (2015) Assessment of fractional flow reserve in patients with recent Non–ST-Segment–Elevation Myocardial Infarction. Circulation: Cardiovascular Interventions, 8, (doi: 10.1161/circinterventions.114.002207)

Musunuru, K., Hickey, K. T., Al-Khatib, S. M., Delles, C., Fornage, M., Fox, C. S., Frazier, L., Gelb, B. D., Herrington, D. M., Lanfear, D. E., Rosand, J. (2015) Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. Circulation: Cardiovascular Genetics, 8, pp. 216-242. (doi: 10.1161/HCG.0000000000000020)

Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Jhund, P. S., Brunton, A. P.T., Anand, I. S., McKelvie, R. S., Komajda, M., Zile, M. R., Carson, P. E., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with coronary artery disease and angina. Circulation: Heart Failure, 8, pp. 717-724. (doi: 10.1161/CIRCHEARTFAILURE.114.002024)

Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S., Porteous, D. J., Starr, J., Deary, I. J., Wardlaw, J. M. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46, pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649)

Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C., Currie, G., Schlembach, D., Mohaupt, M.G., Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, (doi: 10.1186/s12958-015-0100-6)

Escola-Gil, J.C., Julve, J., Griffin, B.A., Freeman, D.J., Blanco-Vaca, F. (2015) HDL and lifestyle interventions. Springer Open

Dalzell, J. R., Cannon, J. A., Simpson, J., Gardner, R. S., Petrie, M. C. (2015) Improving outcomes in peripartum cardiomyopathy. Expert Review of Cardiovascular Therapy, 13, pp. 665-671. (doi: 10.1586/14779072.2015.1040767)

Mangion, K., Carrick, D., Payne, A., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K., Berry, C. (2015) Infarct burden following multivessel PCI vs. infarct-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O9)

Mangion, K., Carrick, D., Payne, A. R., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2015) Left ventricular outcomes following multivessel PCI vs. infarct artery-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-P104)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Pathophysiology of myocardial remodeling in survivors of ST-elevation myocardial infarction revealed by native T1 mapping: inflammation, remote myocardium and prognostic significance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-Q52)

Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K. G., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by non-contrast T1 mapping cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O26)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by quantitative T2-weighted cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O54)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of quantitative measures of myocardial infarct pathology using native T1 mapping, in survivors of ST-elevation myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 17, pp. O53. (doi: 10.1186/1532-429X-17-S1-O53)

Badar, A. A., Brunton, A. P.T., Mahmood, A. H., Dobbin, S., Pozzi, A., McMinn, J. F., Sinclair, A. J.E., Gardner, R. S., Petrie, M. C., Curry, P. A., Al-Attar, N. H.K., Pettit, S. J. (2015) The management of patients with aortic regurgitation and severe left ventricular dysfunction: a systematic review. Expert Review of Cardiovascular Therapy, 13, pp. 915-922. (doi: 10.1586/14779072.2015.1067139)

Brown, C. E., McCarthy, N. S., Hughes, A. D.,, Sever, P., Stalmach, A., Mullen, W., Dominiczak, A. F., Sattar, N., Mischak, H., Thom, S., Mayet, J., Stanton, A. V., Delles, C. (2015) Urinary proteomic biomarkers to predict cardiovascular events. Proteomics Clinical Applications, 9, pp. 610-617. (doi: 10.1002/prca.201400195)

Pregnancy is associated with substantial cardiovascular and metabolic changes in a woman’s physiology. These changes are necessary for maternal health and fetal development. In some, the cardiovascular system fails to adapt to these pregnancy-related changes, resulting in systemic effects that can cause morbidity and mortality. Our group is particularly interested in the hemodynamic changes that accompany pregnancy and related conditions such as pre-eclampsia.

Our group, and others, have shown that the cardiovascular consequences of pregnancy do not end with the delivery of the baby. Cardiovascular, metabolic, and other systemic changes associated with unhealthy pregnancy are evident across the life course. Pregnancy syndromes as a risk factor for future cardiovascular disease is a particular interest of the group.

Advances in obstetric medicine, alongside changing societal demographics, mean that more people living with cardiovascular and metabolic diseases are becoming pregnant. We are interested in how conditions like maternal obesity increase the risk for short- and long-term pregnancy-related complications. Ultimately, we hope to use this mechanistic understanding to help identify potential new ways of intervening in the development of these diseases.

Ongoing research topics include:

  • Studies into the pathogenesis of hypertension in pregnancy and placental syndromes.
  • Prediction of preeclampsia by biomarkers and vascular properties.
  • The role of ectopic fat in the placenta in gestational diabetes and pre-eclampsia.
  • The long-term consequences of preeclampsia on cardiovascular and cerebral health.