Kidney Disease

We aim to improve the health for people with, or at risk of kidney disease by addressing its impact on cardiovascular disease, cancer, infection, quality of life and survival.

Staff

Publications

2024

Greenlees, C., Hosseinzadeh, S., Delles, C., Mcginnigle, E. (2024) Hypertension evaluation and management in new young patients: are we doing our female patients a disservice? Blood Pressure, 33, (doi: 10.1080/08037051.2024.2387909)

Main, A., Mary, S., Sin, Y. Y., Wright, T. A., Ling, J., Blair, C. M., Smith, G. L., Fuller, W., Baillie, G. S. (2024) SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline. International Journal of Biochemistry and Cell Biology, 176, (doi: 10.1016/j.biocel.2024.106668)

Rochmawati, I. D., Deo, S., Lees, J. S., Mark, P. B., Sattar, N., Celis-Morales, C., Pell, J. P., Welsh, P., Ho, F. K. (2024) Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20,656 patients with cardiovascular disease. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae352)

Xiong, X., Lui, D. T.W., Ju, C., Zhou, Z., Xu, C., Welsh, P., Sattar, N., Celis-Morales, C., Pell, J. P., Wong, I. C.K., Wong, C. K.H., Ho, F. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (doi: 10.1002/jcsm.13611)

Dieden, A., Girerd, N., Ottosson, F., Molvin, J., Pareek, M., Melander, O., Bachus, E., Råstam, L., Lindblad, U., Daka, B., Leósdóttir, M., Nilsson, P. M., Olsen, M. H., Clark, A. L., Cleland, J. G.F., Delles, C., González, A., Lamiral, Z., Duarte, K., Rossignol, P., Zannad, F., Gudmundsson, P., Jujić, A., Magnusson, M. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502)

Foley, P.W., Kalra, P.R., Cleland, J.G.F., Petrie, M.C., Kalra, P.A., Squire, I., Campbell, P., Chapman, C., Donnelly, P., Graham, F., Hannah, A., Lang, N.N., Matthews, I., Leslie, S.J., Pellicori, P., Piper, S., Ray, R., Savage, H.O., Spencer, C., Walsh, J., Wong, Y., Ford, I. (2024) Effect of correcting iron deficiency on the risk of serious infection in heart failure insights from the IRONMAN trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3504)

Pontiroli, A. E., Tagliabue, E., Madotto, F., Leoni, O., Antonelli, B., Carluccio, E., Bandera, F., Galati, G., Pellicori, P., Lund, L. H., Ambrosio, G. (2024) Association of non-cardiac comorbidities and sex with long-term re-hospitalization for heart failure. European Journal of Internal Medicine,

Walker, H., Sullivan, M. K., Jani, B. D., Mark, P. B., Gallacher, K. I. (2024) Exploration of patients’ and health care professionals’ perspectives of kidney failure risk and the use of the kidney failure risk equation in MULTIPle lOng-term condItions aNd frailTy (MULTIPOINT) study: a qualitative interview and focus group study protocol. BMJ Open, 14, (doi: 10.1136/bmjopen-2024-085843)

Varga, C. R., Cleland, J. G.F., Abraham, W. T., Lip, G. Y.H., Leyva, F., Hatamizadeh, P. (2024) Implantable cardioverter defibrillator and resynchronization therapy in patients with overt chronic kidney disease. Journal of the American College of Cardiology, 84, pp. 1342-1362. (doi: 10.1016/j.jacc.2024.05.081)

Ho, F., Allan, M., Shao, H., Man, K. K.C., Jani, B. D., Lyall, D., Hastie, C., Fleming, M., Mackay, D., Cleland, J. G.F., Delles, C., Dundas, R., Lewsey, J., Ip, P., Wong, I., Welsh, P., Pearce, A., Wright, C. M., Minnis, H., Katikireddi, V., Pell, J. P. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health Europe, (doi: 10.1016/j.lanepe.2024.101075)

Lee, M., Petrie, M. C., Cleland, J. G.F., Donnelly, P., Francis, M., Hannah, A., Japp, A. G., Labinjoh, C., Lang, N. N., Mainsty, C., Petrie, C. J., Piper, S. E., Williams, S. G., Ford, I., Kalra, P. R., IRONMAN Trial Investigators, (2024) Administration of ferric derisomaltose for iron deficiency and heart failure during hospital admission or at the clinic – insights from the IRONMAN trial. European Journal of Heart Failure, 26, pp. 2293-2295. (doi: 10.1002/ejhf.3394)

Liu, Q., Celis-Morales, C., Lees, J. S., Sattar, N., Ho, F., Pell, J. P., Mark, P. B., Welsh, P. (2024) Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 15, pp. 2046-2055. (doi: 10.1002/jcsm.13551)

Cleland, J. G.F. (2024) Home-time is good, but feeling well is better: patient-journey and quality-home-time as endpoints in heart failure trials and registries. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012263)

Pellicori, P., Cuthbert, J. J., Clark, A. L., Cleland, J. G.F. (2024) Managing water and salt balance in heart failure: Is there anything else to consider other than diet and diuretics? European Journal of Heart Failure, 26, pp. 2140-2142. (doi: 10.1002/ejhf.3374)

Keene, D. et al. (2024) Predictors of the efficacy of His bundle pacing in patients with a prolonged PR interval: A stratified analysis of the HOPE‐HF randomized controlled trial. European Journal of Heart Failure, 26, pp. 2261-2268. (doi: 10.1002/ejhf.3367)

Yu, Y.-L. et al. (2024) Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, 110, pp. 1180-1187. (doi: 10.1136/heartjnl-2023-323796)

Beazer, J. D., Sillars, A., Beck, S., Christoffersen, C., Ferraz, M. J., Mulder, M., Graham, D., Karlsson, H., Ljunggren, S. A., Gill, J. M. R., Freeman, D. J. (2024) Favourable HDL composition in endurance athletes is not associated with changes in HDL in vitro antioxidant and endothelial anti-inflammatory function. Bioscience Reports, (doi: 10.1042/BSR20241165)

Cheng, L., Hammersley, D., Ragavan, A., Javed, S., Mukhopadhyay, S., Gregson, J., Han, J., Khalique, Z., Lota, A., Pantazis, A., Baksi, A. J., Carr‐White, G., de Marvao, A., Ware, J., Tayal, U., Pennell, D. J., Cleland, J. G.F., Prasad, S. K., Halliday, B. P. (2024) Long‐term follow‐up of the TRED ‐ HF trial: Implications for therapy in patients with dilated cardiomyopathy and heart failure remission. European Journal of Heart Failure, (doi: 10.1002/ejhf.3475)

Walker, H., Day, S., Grant, C. H., Jones, C., Ker, R., Sullivan, M. K., Jani, B. D., Gallacher, K., Mark, P. B. (2024) Representation of multimorbidity and frailty in the development and validation of kidney failure prognostic prediction models: a systematic review. BMC Medicine,

Anderson, J. J., Deo, S. V., Welsh, P., Mackay, D. F., Ho, F. K., Ferguson, L. D., Celis-Morales, C., Gill, J.R., Pell, J. P., Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949)

Valentova, M., Vatic, M., Garfias-Veitl, T., Sandek, A., Bekfani, T., Jankowska, E. A., Cleland, J. G.F., Clark, A. L., Lainscak, M., Ahmed, A., Jauert, N., Hasenfuss, G., Anker, S. D., Doehner, W., von Haehling, S. (2024) Diabetes mellitus is associated with low exercise capacity and impaired peripheral vasodilation in patients with heart failure – a propensity score-matched stud. Diabetes Research and Clinical Practice,

Greene, S. J. et al. (2024) Cardiovascular and renal treatment in heart failure patients with hyperkalemia or high risk of hyperkalemia: rationale and design of the CARE-HK in HF registry. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2024.08.048)

Zhou, M., Mary, S., Delles, C., Padmanabhan, S., Graham, D., McBride, M. W., Dominiczak, A. (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0)

Cuthbert, J. J., Cleland, J. G. F., Pellicori, P., Clark, A. L. (2024) Natriuresis guided diuresis in patients admitted to hospital with heart failure – barking up the wrong tree? Journal of Cardiac Failure,

Marshall, W. R., Curran, G. A., Traynor, J. P., Gillis, K. A., Mark, P. B., Lees, J. S. (2024) Sodium zirconium cyclosilicate treatment and rates of emergency interventions for hyperkalaemia: a propensity-score weighted case-control study. Clinical Kidney Journal, (doi: 10.1093/ckj/sfae313)

Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901)

Al-Abdullah, L., Ahern, A., Welsh, P., Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, 26, pp. 3653-3662. (doi: 10.1111/dom.15706)

Reza, N., Pellicori, P., Starling, R. C. (2024) REVOLUTION in heart failure care and SELECT highlights from the European Society of Cardiology-Heart Failure Association Heart Failure and World Congress on Acute Heart Failure 2024. Journal of Cardiac Failure, 30, pp. 1157-1160. (doi: 10.1016/j.cardfail.2024.05.004)

McNeilly, S. et al. (2024) Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage. EBioMedicine, 107, (doi: 10.1016/j.ebiom.2024.105315)

Di Fiore, V., Del Punta, L., De Biase, N., Pellicori, P., Gargani, L., Dini, F. L., Armenia, S., Vigni, M. L., Maremmani, D., Masi, S., Taddei, S., Pugliese, N. R. (2024) Integrative assessment of congestion in heart failure using ultrasound imaging. Internal and Emergency Medicine,

Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycaemic control with intraocular pressure in a large general population: Results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)

Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycemic control with intraocular pressure in a large general population: results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)

Ponikowski, P. et al. (2024) Hospitalizations in symptomatic patients with heart failure and moderate to severe functional mitral regurgitation: insights from RESHAPE-HF2. JACC: Heart Failure,

Graham, F. J., Guha, K., Cleland, J. G., Kalra, P. R. (2024) Treating iron deficiency in patients with heart failure: what, why, when, how, where and who. Heart, (doi: 10.1136/heartjnl-2022-322030)

Cleland, J., Pellicori, P., Graham, F. J., Lane, R., Petrie, M. C., Ahmed, F., Squire, I. B., Ludman, A., Japp, A., Al-Mohammad, A., Clark, A. L., Szwejkowski, B., Critoph, C., Chong, V., Schiff, R., Nageh, T., Glover, J., McMurray, J. J.V., Thomson, E. A., Robertson, M., Ford, I., Kalra, P. A., Kalra, P. R. (2024) The IRONMAN trial of intravenous iron for heart failure. Adjudication of hospitalizations and deaths. Journal of the American College of Cardiology,

Elyan, B. M.P., Sullivan, M. K., Hedley, J., De La Mata, N., Webster, A. C., Venugopal, B., Jones, R. J., Lang, N. N., Mark, P. B., Lees, J. S. (2024) The impact of VEGF signalling pathway inhibitors and/or immune checkpoint inhibitors on kidney function over time: a single centre retrospective analysis. BJC Reports, 2, (doi: 10.1038/s44276-024-00081-7)

Cao, T. H., Tay, W. T., Jones, D. J.L., Cleland, J. G.F., Tromp, J., Emmens, J. E., Teng, T.‐H. K., Chandramouli, C., Slingsby, O. C., Anker, S. D., Dickstein, K., Filippatos, G., Lang, C. C., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Anand, I. S., Lam, C. S.P., Voors, A. A., Ng, L. L. (2024) Heart failure with improved versus persistently reduced left ventricular ejection fraction: A comparison of the BIOSTAT‐CHF (European) study with the ASIAN‐HF registry. European Journal of Heart Failure, (doi: 10.1002/ejhf.3378)

Kazmi, S., Kambhampati, C., Rigby, A. S., Cleland, J. G.F., Kazmi, K. S., Cuthbert, J., Pellicori, P., Clark, A. L. (2024) Disease progression in chronic heart failure is linear: insights from multistate modelling. European Journal of Heart Failure, (doi: 10.1002/ejhf.3400)

Schofield, C., Sarrigiannidis, S., Moran-Horowich, A., Jackson, E., Rodrigo-Navarro, A., Van Agtmael, T., Cantini, M., Dalby, M. J., Salmeron-Sanchez, M. (2024) An in vitro model of the blood-brain barrier for the investigation and isolation of the key drivers of barriergenesis. Advanced Healthcare Materials, (doi: 10.1002/adhm.202303777)

Gustafsson, F., Petrie, M. C., Komtebedde, J., Swarup, V., Winkler, S., Hasenfuß, G., Borlaug, B. A., Mohan, R. C., Flaherty, J. D., Sverdlov, A. L., Fail, P. S., Chung, E. S., Lurz, P., Lilly, S., Kaye, D. M., Cleland, J. G.F., Cikes, M., Leon, M. B., Cutlip, D. E., van Veldhuisen, D. J., Solomon, S. D., Shah, S. J. (2024) 2-year outcomes of an atrial shunt device in HFpEF/HFmrEF: results from REDUCE LAP-HF II. JACC: Heart Failure, 12, pp. 1425-1438. (doi: 10.1016/j.jchf.2024.04.011)

Lam, C. S.P., Køber, L., Kuwahara, K., Lund, L. H., Mark, P. B., Mellbin, L. G., Schou, M., Ely Pizzato, P., Gabrielsen, A., Gasparyan, S. B., Ghiretti, A., Hartleib‐Geschwindner, J., Housler, G. J., Fanti, P., Leonsson‐Zachrisson, M., McMurray, J. J.V., Solomon, S. D. (2024) Balcinrenone plus dapagliflozin in patients with heart failure and chronic kidney disease: Results from the phase 2b MIRACLE trial. European Journal of Heart Failure, 26, pp. 1727-1735. (doi: 10.1002/ejhf.3294)

Sudesh, S., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Friedman, D. J., Gold, M. R., Kutyifa, V., Linde, C., Tang, A. S., Olivas-Martinez, A., Inoue, L. Y.T., Sanders, G. D., Al-Khatib, S. M. (2024) Cardiac resynchronization therapy in ischemic versus non-ischemic cardiomyopathy: patient-level meta-analysis of seven randomized clinical trials. JACC: Heart Failure,

Carberry, J., Petrie, M. C., Lee, M. M.Y., Brooksbank, K., Campbell, R. T., Good, R., Jhund, P. S., Kellman, P., Lang, N. N., Mangion, K., Mark, P. B., McConnachie, A., McMurray, J. J.V., Meyer, B., Orchard, V., Shaukat, A., Watkins, S., Welsh, P., Sattar, N., Berry, C., Docherty, K. F. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure, 11, pp. 2001-2012. (doi: 10.1002/ehf2.14830)

Grobbee, D. E., Filippatos, G., Desai, N. R., Coats, A. J.S., Pinto, F., Rosano, G. M.C., Cleland, J., Kammerer, J., Ramirez de Arellano, A. (2024) Epidemiology and risk factors for hyperkalaemia in heart failure. ESC Heart Failure, 11, pp. 1821-1840. (doi: 10.1002/ehf2.14661)

Docherty, K. F., McMurray, J. J.V., Kalra, P., Cleland, J. G.F., Lang, N. N., Petrie, M. C., Robertson, M., Ford, I. (2024) Intravenous iron and SGLT2 inhibitors in iron-deficient patients with heart failure and reduced ejection fraction. ESC Heart Failure, 11, pp. 1875-1879. (doi: 10.1002/ehf2.14742)

Madero, M., Chertow, G. M., Mark, P. B. (2024) SGLT2 inhibitor use in chronic kidney disease: supporting cardiovascular, kidney, and metabolic health. Kidney Medicine, 6, (doi: 10.1016/j.xkme.2024.100851)

Delles, C., Setjiadi, D., Geddes, C. (2024) Blood pressure measurement technique in clinical practice. Research Square, (doi: 10.21203/rs.3.rs-4635130/v1)

Shead, K. D., Huethorst, E., Burton, F., Lang, N., Myles, R. C., Smith, G. L. (2024) Human induced pluripotent stem cell derived cardiomyocytes for pre-clinical cardiotoxicity screening. JACC: CardioOncology,

Sullivan, M. K., Lees, J. S., Rosales, B. M., Cutting, R., Wyld, M. L., Woodward, M., Webster, A. C., Mark, P. B., De La Mata, N. (2024) Sex and the relationship between cardiometabolic risk factors and estimated GFR Decline: a population-based cohort study. American Journal of Kidney Diseases, (doi: 10.1053/j.ajkd.2024.05.007)

Bahar, J., Rahman, A., Wong, G. W.Y., Sankaranarayanan, R., Ahmed, F. Z., Taylor, R., Fuat, A., Squire, I., Cleland, J., Lip, G. Y.H., Gamble, J. H.P., Masudi, S., Joseph, P. J. S., Wong, K. (2024) Outpatient treatment of decompensated heart failure: a systematic review and study level meta-analysis. ESC Heart Failure, (doi: 10.1002/ehf2.14841)

Collister, D., Pyne, L., Bhasin, A. A., Smyth, B., Herrington, W., Jardine, M., Mark, P. B., Badve, S., Rossignol, P., Dember, L. M., Wanner, C., Ezekowitz, J., Deveraux, P.J., Parfrey, P., Gansevoort, R., Walsh, M. (2024) Heart failure events in randomized controlled trials for adults receiving maintenance dialysis: a meta-epidemiologic study. Nephrology Dialysis Transplantation, (doi: 10.1093/ndt/gfae156)

Rubiś, P. P., Dziewięcka, E., González, A., Cleland, J. G.F. (2024) High variability in assays of blood markers of collagen turnover in cardiovascular disease: Implications for research and clinical practice. European Journal of Heart Failure, (doi: 10.1002/ejhf.3375)

Zac-Varghese, S., Mark, P., Bain, S., Banerjee, D., Chowdhury, T. A., Dasgupta, I., De, P., Fogarty, D., Frankel, A., Goldet, G., Karalliedde, J., Mallik, R., Montero, R., Sharif, A., Wahba, M., Dhatariya, K., McCafferty, K., Lioudaki, E., Winocour, P. (2024) Clinical practice guideline for the management of lipids in adults with diabetic kidney disease: abbreviated summary of the Joint Association of British Clinical Diabetologists and UK Kidney Association (ABCD-UKKA) Guideline 2024. BMC Nephrology, 25, (doi: 10.1186/s12882-024-03664-1)

Aguiar-Neves, I., Diaz, S. O., Ferreira, J. P., Girerd, N., Pellicori, P., Mariottoni, B., Cosmi, F., Hazebroek, M., Verdonschot, J. A.J., Cuthbert, J., Petutschnigg, J., Heymans, S., Staessen, J. A., Pieske, B., Edelmann, F., Clark, A. L., Rossignol, P., Fontes-Carvalho, R., Cleland, J. G., Zannad, F. (2024) Health status and effects of spironolactone in people at high risk of heart failure: the Heart OMics in AGEing (HOMAGE) randomised trial. Clinical Cardiology,

Churuangsuk, C., Catchpole, A., Talwar, D., Welsh, P., Sattar, N., Combet Aspray, E., Lean, M. E.J. (2024) Low thiamine status in adults following low-carbohydrate / ketogenic diets: a cross-sectional comparative study of micronutrient intake and status. European Journal of Nutrition, (doi: 10.1007/s00394-024-03459-y)

Packer, M., Cleland, J. G.F., Bauersachs, J. (2024) Great debate: SGLT2 inhibitors should be first-line treatment in heart failure with reduced ejection fraction. European Heart Journal, 45, pp. 2186-2196. (doi: 10.1093/eurheartj/ehae300)

Cannata, A., Mizani, M. A., Bromage, D. I., Piper, S. E., Hardman, S. M.C., Sudlow, C., de Belder, M., Deanfield, J., Gardner, R. S., Clark, A. L., Cleland, J. G.F., McDonagh, T. A. (2024) A nationwide, population-based study on specialized care for acute heart failure throughout the COVID-19 pandemic. European Journal of Heart Failure, 26, pp. 1574-1584. (doi: 10.1002/ejhf.3306)

Lakhal-Littleton, S., Cleland, J. G. F. (2024) Iron deficiency and supplementation in heart failure. Nature Reviews Cardiology, 21, pp. 463-486. (doi: 10.1038/s41569-024-00988-1)

Denicolò, S., Reinstadler, V., Keller, F., Thöni, S., Eder, S., Heerspink, H. J.L., Rosivall, L., Wiecek, A., Mark, P. B., Perco, P., Leierer, J., Kronbichler, A., Oberacher, H., Mayer, G. (2024) Non-adherence to antidiabetic and cardiovascular medication as assessed by LC-MS/MS in urine and its association with kidney and cardiovascular outcomes in type 2 diabetes mellitus. Diabetologia, 67, pp. 1283-1294. (doi: 10.1007/s00125-024-06149-w)

Denicolò, S., Reinstadler, V., Keller, F., Thöni, S., Eder, S., Heerspink, H. J. L., Rosivall, L., Wiecek, A., Mark, P. B., Perco, P., Leierer, J., Kronbichler, A., Oberacher, H., Mayer, G. (2024) Non-adherence to cardiometabolic medication as assessed by LC-MS/MS in urine and its association with kidney and cardiovascular outcomes in type 2 diabetes mellitus. Diabetologia, 67, pp. 1283-1294. (doi: 10.1007/s00125-024-06149-w)

Anker, S. D. et al. (2024) Percutaneous repair of moderate-to-severe or severe functional mitral regurgitation in patients with symptomatic heart failure: Baseline characteristics of patients in the RESHAPE-HF2 trial and comparison to COAPT and MITRA-FR trials. European Journal of Heart Failure, 26, pp. 1608-1615. (doi: 10.1002/ejhf.3286)

Kulkarni, S., Faconti, L., Partridge, S., Delles, C., Glover, M., Lewis, P., Gray, A., Hodson, E., Macintyre, I., Maniero, C., McEniery, C. M., Sinha, M. D., Walsh, S. B., Wilkinson, I. B. (2024) Investigation and management of young-onset hypertension: British and Irish Hypertension Society position statement. Journal of Human Hypertension, (doi: 10.1038/s41371-024-00922-5)

Conrad, N., Molenberghs, G., Verbeke, G., Zaccardi, F., Lawson, C., Friday, J. M., Su, H., Jhund, P. S., Sattar, N., Rahimi, K., Cleland, J. G., Khunti, K., Budts, W., McMurray, J. J.V. (2024) Temporal trends and patterns in cardiovascular disease incidence: a population-based study in 22 million individuals. British Medical Journal, 385, (doi: 10.1136/bmj-2023-078523)

Chertow, G. M., Heerspink, H. L., Mark, P. B., Dwyer, J. P., Nowickig, M., Wheeler, D. C., Correa-Rotter, R., Rossing, P., Toto, R. D., Langkilde, A. M., Jongs, N. (2024) Effects of dapagliflozin in patients with membranous nephropathy. Glomerular Diseases, 4, pp. 137-145. (doi: 10.1159/000539770)

Friday, J. M., Cleland, J., Pellicori, P., Wolters, M., McMurray, J. J.V., Jhund, P. S., Forsyth, P., McAllister, D. A., Graham, F. J., Jones, Y., Lewsey, J. (2024) Loop diuretic utilisation with or without heart failure: impact on prognosis. European Heart Journal, (doi: 10.1093/eurheartj/ehae345)

Rankin, S., Fountain, C., Gemmell, A., Quinn, D., Henderson, A., McClure, J., Small, S., Venugopal, B., McKay, P., Slomka, P. J., Colville, D., Petrie, M. C., Meléndez, G. C., Lang, N. N. (2024) Arterial effects of anthracycline: structural and inflammatory assessments in non-human primates and lymphoma patients using 18F-FDG positron emission tomography. bioRxiv, (doi: 10.1101/2024.05.30.596741)

Padmanabhan, S., Delles, C., Dominiczak, A. F. (2024) Beyond genome-wide scans: advancing hypertension genomics into the future. Hypertension, 81, pp. 1186-1189. (doi: 10.1161/HYPERTENSIONAHA.124.21371)

Packer, M., Anker, S. D., Butler, J., Cleland, J. G.F., Kalra, P. R., Mentz, R. J., Ponikowski, P., Talha, K. M. (2024) Critical re‐evaluation of the identification of iron deficiency states and effective iron repletion strategies in patients with chronic heart failure. European Journal of Heart Failure, 26, pp. 1298-1312. (doi: 10.1002/ejhf.3237)

Curtain, J. P., Talebi, A., McIntosh, A., McConnachie, A., O’Donnell, J., Welsh, P., Osmanska, J., Lee, M. M.Y., Sonecki, P., Akl, T., Seo, J., Gopinathan, V., Hurwitz, J., Thiagarajan, S., Pettit, S., Kalra, P. R., Patel, R. K., Mark, P. B., Lang, N. N., McMurray, J. J.V., Petrie, M. C., Gardner, R. S., Jhund, P. S. (2024) Measuring congestion with a non-invasive monitoring device in heart failure and haemodialysis: CONGEST-HF. European Journal of Heart Failure, 26, pp. 1383-1392. (doi: 10.1002/ejhf.3290)

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Pellicori, P., Cleland, J. G.F. (2024) Atrial myopathy and heart failure with preserved ejection fraction: When a label does more harm than good? European Journal of Heart Failure, 26, pp. 299-301. (doi: 10.1002/ejhf.3148)

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Kharlamov, A., Sherriff, N., Delles, C., van der Harst, P. (2024) Tackling cardiovascular healthcare disparities for LGBTQIA+ population: a call to action in the European Society of Cardiology. European Heart Journal, (doi: 10.1093/eurheartj/ehad882)

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2023

Caiazzo, E., Sharma, M., Rezig, A. O.M., Morsy, M. I., Czesnikiewicz-Guzik, M., Ialenti, A., Sulicka-Grodzicka, J., Pellicori, P., Crouch, S. H., Schutte, A. E., Bruzzese, D., Maffia, P., Guzik, T. J. (2023) Circulating cytokines and risk of developing hypertension: a systematic review and meta-analysis. Pharmacological Research, 200, (doi: 10.1016/j.phrs.2023.107050)

Glen, C., Adam, S., Coats, C. J., Lang, N. N. (2023) Reply: Cardiotoxicity of BRAF/MEK inhibitors according to HFA/ICOS cardiotoxicity risk category. JACC: CardioOncology, 5, pp. 850. (doi: 10.1016/j.jaccao.2023.10.003)

Mayne, K. J. et al. (2023) Effects of empagliflozin on fluid overload, weight and blood pressure in chronic kidney disease. Journal of the American Society of Nephrology, (doi: 10.1681/ASN.0000000000000271)

Bagordo, D., Rossi, G. P., Delles, C., Wiig, H., Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569)

Welsh, S. A., Hussey, K., Brittenden, J., Orr, D. J., Quinn, T. (2023) Frailty Assessment in Vascular OUtpatients Review (FAVOUR) PROTOCOL – single-centre prospective cohort study comparing feasibility and prognostic value of commonly used frailty assessment tools. BMJ Open, 13, (doi: 10.1136/bmjopen-2023-079387)

Welsh, P., Kimenai, D. M., Shah, A. S.V., Gadd, D. A., Marioni, R. E., Woodward, M., Sudlow, C. L.M., Campbell, A., Cleland, J. G.F., Pellicori, P., Hayward, C., Mills, N. L., Sattar, N. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study. Clinical Chemistry, 70, pp. 403-413. (doi: 10.1093/clinchem/hvad205)

Camargo, L. L., Wang, Y., Rios, F. J., McBride, M., Montezano, A. C., Touyz, R. M. (2023) Oxidative stress and endoplasmic reticular stress interplay in the vasculopathy of hypertension. Canadian Journal of Cardiology, 39, pp. 1874-1887. (doi: 10.1016/j.cjca.2023.10.012)

Connelly, P., Osmanska, J., Lee, M. M.Y., Delles, C., McEntegart, M. B., Byrne, J. (2023) A case report of myocardial infarction in a young transgender man with testosterone therapy? raising awareness on healthcare issues in the transgender community and a call for further research. European Heart Journal: Case Reports, 7, (doi: 10.1093/ehjcr/ytad562)

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2022

Lithgow, H., Johnston, L., Ho, F. K., Celis-Morales, C., Cobley, J., Raastad, T., Hunter, A. M., Lees, J. S., Mark, P. B., Quinn, T. J., Gray, S. R. (2022) Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle-damaging resistance exercise in young and older adults—the TAKEOVER study. Trials, 23, (doi: 10.1186/s13063-022-06937-y)

Kalra, P. R., Cleland, J. G.F., Petrie, M. C., Thomson, E. A., Kalra, P. A., Squire, I. B., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Foley, P. W.X., Graham, F. J., Japp, A. G., Lane, R. E., Lang, N. N., Ludman, A. J., Macdougall, I. C., Pellicori, P., Ray, R., Robertson, M., Seed, A., Ford, I. (2022) Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial. Lancet, 400, pp. 2199-2209. (doi: 10.1016/S0140-6736(22)02083-9)

McGettrick, M., Dormand, H., Brewis, M., Johnson, M. K., Lang, N. N., Church, A. C. (2022) Cardiac geometry, as assessed by cardiac magnetic resonance, can differentiate subtypes of chronic thromboembolic pulmonary vascular disease. Frontiers in Cardiovascular Medicine, 9, (doi: 10.3389/fcvm.2022.1004169)

Bhandari, S., Mehta, S., Khwaja, A., Cleland, J. G.F., Ives, N., Brettell, E., Chadburn, M., Cockwell, P. (2022) Renin-angiotensin system inhibition in advanced chronic kidney disease. New England Journal of Medicine, 387, pp. 2021-2032. (doi: 10.1056/NEJMoa2210639)

Saxena, P., Myles, R. C., Smith, G. L., Workman, A. J. (2022) Adrenoceptor sub-type involvement in Ca2+ current stimulation by noradrenaline in human and rabbit atrial myocytes. Pflügers Archiv European Journal of Physiology, 474, pp. 1311-1321. (doi: 10.1007/s00424-022-02746-z)

Lees, J. S., Shlipak, M. G. (2022) Age-adapted eGFR thresholds underestimate the risks beyond kidney failure associated with CKD in older populations. Journal of the American Geriatrics Society, 70, pp. 3660-3664. (doi: 10.1111/jgs.18046)

Monzo, L., Ferreira, J. P., Cleland, J. G.F., Pellicori, P., Mariottoni, B., Hazebroek, M. R., Collier, T. J., Cuthbert, J. J., Pieske, B., Petutschnigg, J., Ahmed, F. Z., Girerd, N., Clark, A. L., Cosmi, F., Staessen, J. A., Heymans, S., Rossignol, P., Zannad, F. (2022) Dyskalemia in people at increased risk for heart failure: findings from the heart ‘OMics’ in AGEing (HOMAGE) trial. ESC Heart Failure, 9, pp. 4352-4357. (doi: 10.1002/ehf2.14086)

Pugliese, N. R., Pellicori, P., Filidei, F., De Biase, N., Maffia, P., Guzik, T. J., Masi, S., Taddei, S., Cleland, J. G.F. (2022) Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions. Cardiovascular Research, 118, pp. 3536-3555. (doi: 10.1093/cvr/cvac133)

Bracun, V., van Essen, B., Voors, A. A., van Veldhuisen, D. J., Dickstein, K., Zannad, F., Metra, M., Anker, S., Samani, N. J., Ponikowski, P., Filippatos, G., Cleland, J. G.F., Lang, C. C., Ng, L. L., Shi, C., de Wit, S., About Msallem, J. P., Meijers, W. C., Klip, I. T., van der Meer, P., de Boer, R. A. (2022) Insulin‐like growth factor binding protein 7 (IGFBP7), a link between heart failure and senescence. ESC Heart Failure, 9, pp. 4167-4176. (doi: 10.1002/ehf2.14120)

Mark, P. B., Mangion, K., Rankin, A. J., Rutherford, E., Lang, N. N., Petrie, M. C., Stoumpos, S., Patel, R. K. (2022) Left ventricular dysfunction with preserved ejection fraction: the most common left ventricular disorder in chronic kidney disease patients. Clinical Kidney Journal, 15, pp. 2186-2199. (doi: 10.1093/ckj/sfac146)

Rossitto, G., Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289, pp. 7260-7273. (doi: 10.1111/febs.16155)

de Wit, S., Glen, C., de Boer, R. A., Lang, N. N. (2022) Mechanisms shared between cancer, heart failure, and targeted anti-cancer therapies. Cardiovascular Research, 118, pp. 3451-3466. (doi: 10.1093/cvr/cvac132)

Kalra, P. R., Cleland, J. G. F., Petrie, M. C., Ahmed, F. Z., Foley, P. W. X., Kalra, P. A., Lang, N. N., Lane, R. E., Macdougall, I. C., Pellicori, P., Pope, M. T. B., Robertson, M., Squire, I. B., Thomson, E. A., Ford, I. (2022) Rationale and design of a randomised trial of intravenous iron in patients with heart failure. Heart, 108, pp. 1979-1985. (doi: 10.1136/heartjnl-2022-321304)

Kumar, A. A., Yeo, N., Whittaker, M., Attra, P., Barrick, T. R., Bridges, L. R., Dickson, D. W., Esiri, M. M., Farris, C. W., Graham, D., Lin, W. L., Meijles, D. N., Pereira, A. C., Perry, G., Rosene, D. L., Shtaya, A. B., Van Agtmael, T., Zamboni, G., Hainsworth, A. H. (2022) Vascular collagen type-IV in hypertension and cerebral small vessel disease. Stroke, 53, pp. 3696-3705. (doi: 10.1161/STROKEAHA.122.037761)

Kilpi, F., Soares, A. G., Clayton, G. L., Fraser, A., Welsh, P., Sattar, N., Nelson, S. M., Tilling, K., Lawlor, D. A. (2022) Changes in women’s physical function in mid-life by reproductive age and hormones: a longitudinal study. BMC Women's Health, 22, (doi: 10.1186/s12905-022-02070-9)

Mark, P. B., Sattar, N. (2022) Implementation, not hesitation, for SGLT2 inhibition as foundational therapy for chronic kidney disease. Lancet, 400, pp. 1745-1747. (doi: 10.1016/S0140-6736(22)02164-X)

Paterson, C., Hinterberg, M. A., Morrow, A. J., Sykes, R., Mangion, K., Welsh, P., McConnachie, A., Sattar, N., Berry, C., Williams, S. A. (2022) Utility of a Proteomic Surrogate for Cardiovascular Outcomes to Predict and Monitor COVID-19 Induced Myocarditis. (doi: 10.1161/circ.146.suppl_1.12132)

Butler, J. et al. (2022) Patiromer for the management of hyperkalemia in heart failure with reduced ejection fraction: the DIAMOND trial. European Heart Journal, 43, pp. 4362-4373. (doi: 10.1093/eurheartj/ehac401)

Sullivan, M. K., Carrero, J.-J., Jani, B. D., Anderson, C., McConnachie, A., Hanlon, P., Nitsch, D., McAllister, D. A., Mair, F. S., Mark, P. B., Gasparini, A. (2022) The presence and impact of multimorbidity clusters on adverse outcomes across the spectrum of kidney function. BMC Medicine, 20, (doi: 10.1186/s12916-022-02628-2)

Mayne, K. J., Shemilt, R., Keane, D. F., Lees, J. S., Mark, P. B., Herrington, W. G. (2022) Bioimpedance indices of fluid overload and cardiorenal outcomes in heart failure and chronic kidney disease: a systematic review. Journal of Cardiac Failure, 28, pp. 1628-1641. (doi: 10.1016/j.cardfail.2022.08.005)

Pellicori, P., Kalra, P. R., Clark, A. L., Friday, J., Cleland, J. G. F. (2022) Chronic kidney disease (CKD) and CKD-ism in heart failure – what a mess! European Journal of Heart Failure, 24, pp. 2196-2198. (doi: 10.1002/ejhf.2696)

Inciardi, R. M., Pagnesi, M., Lombardi, C. M., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G. S., Lang, C. C., Ng, L. L., Pellicori, P., Ponikowski, P., Samani, N. J., Zannad, F., van Veldhuisen, D. J., Solomon, S. D., Voors, A. A., Metra, M. (2022) Clinical implications of left atrial changes after optimization of medical therapy in patients with heart failure. European Journal of Heart Failure, 24, pp. 2131-2139. (doi: 10.1002/ejhf.2593)

Karusheva, Y., Ratcliff, M., Mörseburg, A., Barker, P., Melvin, A., Sattar, N., Burling, K., Backmark, A., Roth, R., Jermutus, L., Guiu-Jurado, E., Blueher, M., Welsh, P., Hyvönen, M., O’Rahilly, S. (2022) Common H202D variant in GDF-15 does not affect its bioactivity but can significantly interfere with measurement of its circulating levels. Journal of Applied Laboratory Medicine, 7, pp. 1388-1400. (doi: 10.1093/jalm/jfac055)

Welsh, S., Sam, Z., Seenan, J. P., Nicholson, G. A. (2022) The role of appendicectomy in ulcerative colitis: systematic review and meta-analysis. Inflammatory Bowel Diseases, 28, pp. e147-e148. (doi: 10.1093/ibd/izac191)

Mary, S., Boder, P., Padmanabhan, S., McBride, M. W., Graham, D., Delles, C., Dominiczak, A. F. (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888)

Salah, H. M., Goldberg, L. R., Molinger, J., Felker, G. M., Applefeld, W., Rassaf, T., Tedford, R. J., Mirro, M., Cleland, J. G.F., Fudim, M. (2022) Diaphragmatic function in cardiovascular disease: JACC review topic of the week. Journal of the American College of Cardiology, 80, pp. 1647-1659. (doi: 10.1016/j.jacc.2022.08.760)

Lota, A. S. et al. (2022) Genetic architecture of acute myocarditis and the overlap with inherited cardiomyopathy. Circulation, 146, pp. 1123-1134. (doi: 10.1161/CIRCULATIONAHA.121.058457)

Desai, A. S., Jhund, P. S., Claggett, B. L., Vaduganathan, M., Miao, Z. M., Kondo, T., Barkoudah, E., Brahimi, A., Connolly, E., Finn, P., Lang, N. N., Mc Causland, F. R., McGrath, M., Petrie, M. C., McMurray, J. J.V., Solomon, S. D. (2022) Effect of dapagliflozin on cause-specific mortality in patients with heart failure across the spectrum of ejection fraction. JAMA Cardiology, 7, pp. 1227-1234. (doi: 10.1001/jamacardio.2022.3736)

Baumhove, L., Tromp, J., Figarska, S., van Essen, B. J., Anker, S. D., Dickstein, K., Cleland, J. G., Lang, C. C., Filippatos, G., Ng, L. L., Samani, N. J., Metra, M., van Veldhuisen, D. J., Lam, C. S.P., Voors, A. A., van der Meer, P. (2022) Heart failure with normal LVEF in BIOSTAT-CHF. International Journal of Cardiology, 364, pp. 85-90. (doi: 10.1016/j.ijcard.2022.05.054)

Lees, J. S., Rutherford, E., Stevens, K. I., Chen, D. C., Scherzer, R., Estrella, M. M., Sullivan, M. K., Ebert, N., Mark, P. B., Shlipak, M. G. (2022) Assessment of Cystatin C level for risk stratification in adults with chronic kidney disease. JAMA Network Open, 5, (doi: 10.1001/jamanetworkopen.2022.38300)

Kazmi, S., Kambhampati, C., Cleland, J. G.F., Cuthbert, J., Kazmi, K. S., Pellicori, P., Rigby, A. S., Clark, A. L. (2022) Dynamic risk stratification using Markov chain modelling in patients with chronic heart failure. ESC Heart Failure, 9, pp. 3009-3018. (doi: 10.1002/ehf2.14028)

Mary, S., Rossitto, G., Delles, C. (2022) Pathophysiology of hypertension. Oxford University Press

Welsh, P., Campbell, R. T., Mooney, L., Kimenai, D. M., Hayward, C., Campbell, A., Porteous, D., Mills, N., Lang, N. N., Petrie, M. C., Januzzi, J. L., McMurray, J. J.V., Sattar, N. (2022) Reference ranges for NT-proBNP (N-terminal pro-B-type natriuretic peptide) and risk factors for higher NT-proBNP concentrations in a large general population cohort. Circulation: Heart Failure, 15, pp. 957-967. (doi: 10.1161/CIRCHEARTFAILURE.121.009427)

Cooper, T. J., Pellicori, P., Ushakov, A., Dickstein, K. (2022) Reply to 'Particular challenges in the use of pulmonary vasodilating therapy for patients with pulmonary hypertension secondary to left heart disease' European Journal of Heart Failure, 24, pp. 1990-1992. (doi: 10.1002/ejhf.2690)

Docherty, K. F., Welsh, P., Verma, S., De Boer, R. A., O'Meara, E., Bengtsson, O., Køber, L., Kosiborod, M. N., Hammarstedt, A., Langkilde, A. M., Lindholm, D., Little, D. J., Sjöstrand, M., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Morrow, D. A., Schou, M., Solomon, S. D., Sattar, N., Jhund, P. S., McMurray, J. J.V. (2022) Iron deficiency in heart failure and effect of dapagliflozin: findings from DAPA-HF. Circulation, 146, pp. 980-994. (doi: 10.1161/CIRCULATIONAHA.122.060511)

Ho, F. K., Zhou, Z., Petermann-Rocha, F., Parra-Soto, S., Boonpor, J., Welsh, P., Gill, J. M.R., Gray, S. R., Sattar, N., Pell, J. P., Celis-Morales, C. (2022) Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94 739 UK Biobank participants. Circulation, 146, pp. 883-891. (doi: 10.1161/CIRCULATIONAHA.122.059663)

Ravera, A., Santema, B. T., de Boer, R. A., Anker, S. D., Samani, N. J., Lang, C. C., Ng, L., Cleland, J. G.F., Dickstein, K., Lam, C. S.P., Van Spall, H., Filippatos, G., van Veldhuisen, D. J., Metra, M., Voors, A. A., Sama, I. E. (2022) Distinct pathophysiological pathways in women and men with heart failure. European Journal of Heart Failure, 24, pp. 1532-1544. (doi: 10.1002/ejhf.2534)

Gao, X., Kuo, C.-W., Main, A., Brown, E., Rios, F. J., De Lucca Camargo, L., Mary, S., Wypijewski, K., Gök, C., Touyz, R. M., Fuller, W. (2022) Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7. Cell Calcium, 106, (doi: 10.1016/j.ceca.2022.102639)

Sundström, J., Bodegard, J., Bollmann, A., Vervloet, M. G., Mark, P. B., Karasik, A., Taveira-Gomes, T., Botana, M., Birkeland, K. I., Thuresson, M., Jäger, L., Sood, M. M., VanPottelbergh, G., Tangri, N. (2022) Prevalence, outcomes, and cost of chronic kidney disease in a contemporary population of 2·4 million patients from 11 countries: the CaReMe CKD study. Lancet Regional Health - Europe, 20, (doi: 10.1016/j.lanepe.2022.100438)

Kobayashi, M., Girerd, N., Ferreira, J. P., Kevin, D., Huttin, O., González, A., Bozec, E., Clark, A. L., Cosmi, F., Cuthbert, J., Diez, J., Edelmann, F., Hazebroek, M., Heymans, S., Mariottoni, B., Pellicori, P., Petutschnigg, J., Pieske, B., Staessen, J. A., Verdonschot, J. A.J., Rossignol, P., Cleland, J. G.F., Zannad, F. (2022) The association between markers of type I collagen synthesis and echocardiographic response to spironolactone in patients at risk of heart failure: findings from the HOMAGE trial. European Journal of Heart Failure, 24, pp. 1559-1568. (doi: 10.1002/ejhf.2579)

Clayton, G. L., Soares, A. G., Kilpi, F., Fraser, A., Welsh, P., Sattar, N., Nelson, S. M., Tilling, K., Lawlor, D. A. (2022) Cardiovascular health in the menopause transition: a longitudinal study of up to 3892 women with up to four repeated measures of risk factors. BMC Medicine, 20, (doi: 10.1186/s12916-022-02454-6)

Thomson, P. C., Mark, P. B., Robertson, M., White, C., Anker, S. D., Bhandari, S., Farrington, K., Jardine, A. G., Kalra, P. A., McMurray, J., Reddan, D., Wheeler, D. C., Winearls, C. G., Ford, I., Macdougall, I. C. (2022) An analysis of vascular access thrombosis events from the Proactive IV Iron Therapy in Hemodialysis Patients (PIVOTAL) trial. Kidney International Reports, 7, pp. 1793-1801. (doi: 10.1016/j.ekir.2022.05.008)

Savarese, G., Uijl, A., Ouwerkerk, W., Tromp, J., Anker, S. D., Dickstein, K., Hage, C., Lam, C. S.P., Lang, C. C., Metra, M., Ng, L. L., Orsini, N., Samani, N. J., van Veldhuisen, D. J., Cleland, J. G.F., Voors, A. A., Lund, L. H. (2022) Biomarker changes as surrogate endpoints in early‐phase trials in heart failure with reduced ejection fraction. ESC Heart Failure, 9, pp. 2107-2118. (doi: 10.1002/ehf2.13917)

Pagnesi, M., Adamo, M., Sama, I. E., Anker, S. D., Cleland, J. G.F., Dickstein, K., Filippatos, G. S., Inciardi, R. M., Lang, C. C., Lombardi, C. M., Ng, L. L., Ponikowski, P., Samani, N. J., Zannad, F., van Veldhuisen, D. J., Voors, A. A., Metra, M. (2022) Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure. Clinical Research in Cardiology, 111, pp. 912-923. (doi: 10.1007/s00392-022-01991-7)

Rossignol, P., Silva-Cardoso, J., Kosiborod, M.N., Brandenburg, V., Cleland, J.G., Hadimeri, H., Hullin, R., Makela, S., Mörtl, D., Paoletti, E., Pollock, C., Vogt, L., Jadoul, M., Butler, J. (2022) Pragmatic diagnostic and therapeutic algorithms to optimize new potassium binder use in cardiorenal disease. Pharmacological Research, 182, (doi: 10.1016/j.phrs.2022.106277)

Deo, S. V., Reddy, Y. N.V., Zakeri, R., Karnib, M., Selvaganesan, P., Elgudin, Y., Kilic, A., Rubelowsky, J., Altarabsheh, S. E., Osman, M. N., Josephson, R. A., Mohan, S. K. M., Cmolik, B., Simon, D. I., Rajagopalan, S., Cleland, J. G.F., Sahadevan, J., Sundaram, V. (2022) Revascularization in ischemic heart failure with preserved ejection fraction: a nationwide cohort study. European Journal of Heart Failure, 24, pp. 1427-1438. (doi: 10.1002/ejhf.2446)

Jorbendaze, A., Young, R., Shaburishvili, T., Demyanchuk, V., Buriak, R., Todurov, B., Rudenko, K., Zuber, M., Stämpfli, S. F., Tanner, F. C., Erne, P., Mirro, M., Fudim, M., Goldberg, L. R., Cleland, J. G.F. (2022) Synchronized diaphragmatic stimulation for heart failure using the VisONE system: a first‐in‐patient study. ESC Heart Failure, 9, pp. 2207-2214. (doi: 10.1002/ehf2.13984)

Girerd, N., Von Hunolstein, J.-J., Pellicori, P., Bayés-Genís, A., Jaarsma, T., Lund, L. H., Bilbault, P., Boivin, J.-M., Chouihed, T., Costa, J., Eicher, J.-C., Fall, E., Kenizou, D., Maillier, B., Nazeyrollas, P., Roul, G., Zannad, N., Rossignol, P., Seronde, M.-F. (2022) Therapeutic inertia in the pharmacological management of heart failure with reduced ejection fraction. ESC Heart Failure, 9, pp. 2063-2069. (doi: 10.1002/ehf2.13929)

Lee, M. M.Y. et al. (2022) Effect of empagliflozin on kidney biochemical and imaging outcomes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 146, pp. 364-367. (doi: 10.1161/CIRCULATIONAHA.122.059851)

Kimenai, D. M., Pirondini, L., Gregson, J., Prieto, D., Pocock, S. J., Perel, P., Hamilton, T., Welsh, P., Campbell, A., Porteous, D. J., Hayward, C., Sattar, N., Mills, N. L., Shah, A. S.V. (2022) Socioeconomic deprivation: an important, largely unrecognized risk factor in primary prevention of cardiovascular disease. Circulation, 146, pp. 240-248. (doi: 10.1161/CIRCULATIONAHA.122.060042)

Lewinter, C., Nielsen, T. H., Edfors, L. R., Linde, C., Bland, J. M., LeWinter, M., Cleland, J. G.F., Køber, L., Braunschweig, F., Mansson-Broberg, A. (2022) A systematic review and meta-analysis of beta-blockers and inhibitors of the renin-angiotensin system for preventing left ventricular dysfunction due to anthracyclines or trastuzumab in patients with breast cancer. European Heart Journal, 43, pp. 2562-2569. (doi: 10.1093/eurheartj/ehab843)

Cowie, M., Cleland, J. G.F. (2022) The COVID-19 pandemic and heart failure: lessons from GUIDE-HF. European Heart Journal, 43, pp. 2619-2621. (doi: 10.1093/eurheartj/ehac226)

Cester, L., Starshynov, I., Jones, Y., Pellicori, P., Cleland, J. G.F., Faccio, D. (2022) Remote laser-speckle sensing of heart sounds for health assessment and biometric identification. Biomedical Optics Express, 13, pp. 3743-3750. (doi: 10.1364/BOE.451416)

Rao, S., Li, Y., Ramakrishnan, R., Hassaine, A., Canoy, D., Cleland, J. G., Lukasiewicz, T., Salimi-Khorshidi, G., Rahimi, K. (2022) An explainable transformer-based deep learning model for the prediction of incident heart failure. IEEE Journal of Biomedical and Health Informatics, 26, pp. 3362-3372. (doi: 10.1109/JBHI.2022.3148820)

Colaço, K., Lee, K.‐A., Akhtari, S., Winer, R., Welsh, P., Sattar, N., McInnes, I. B., Chandran, V., Harvey, P., Cook, R. J., Gladman, D. D., Piguet, V., Eder, L. (2022) Association of cardiac biomarkers with cardiovascular outcomes in patients with psoriatic arthritis and psoriasis: a longitudinal cohort study. Arthritis and Rheumatology, 74, pp. 1184-1192. (doi: 10.1002/art.42079)

Cooper, T. J., Cleland, J. G.F., Guazzi, M., Pellicori, P., Ben Gal, T., Amir, O., Al‐Mohammad, A., Clark, A. L., McConnachie, A., Steine, K., Dickstein, K. (2022) Effects of sildenafil on symptoms and exercise capacity for heart failure with reduced ejection fraction and pulmonary hypertension (the SilHF study): a randomised placebo‐controlled multicentre trial. European Journal of Heart Failure, 24, pp. 1239-1248. (doi: 10.1002/ejhf.2527)

Santema, B. T., Artola Arita, V., Sama, I. E., Kloosterman, M., van den Berg, M. P., Nienhuis, H. L.A., Van Gelder, I. C., van der Meer, P., Zannad, F., Metra, M., Ter Maaten, J. M., Cleland, J. G., Ng, L. L., Anker, S. D., Lang, C. C., Samani, N. J., Dickstein, K., Filippatos, G., van Veldhuisen, D. J., Lam, C. S.P., Rienstra, M., Voors, A. A. (2022) Pathophysiological pathways in patients with heart failure and atrial fibrillation. Cardiovascular Research, 118, pp. 2478-2487. (doi: 10.1093/cvr/cvab331)

Henriksen, P. A., Hall, P., Oikonomidou, O., MacPherson, I. R., Maclean, M., Lewis, S., McVicars, H., Broom, A., Scott, F., McKay, P., Borley, A., Rowntree, C., Lord, S., Collins, G., Radford, J., Guppy, A., Payne, J. R., Newby, D. E., Mills, N. L., Lang, N. N. (2022) Rationale and design of the Cardiac CARE trial: A randomized trial of troponin-guided neurohormonal blockade for the prevention of anthracycline cardiotoxicity. Circulation: Heart Failure, 15, (doi: 10.1161/CIRCHEARTFAILURE.121.009445)

Cohen, D. J., Magnuson, E., Stone, G. W., Cleland, J. G.F. (2022) Response to: correspondence on 'Cost-effectiveness of transcatheter edge-to-edge repair in secondary mitral regurgitation does need confirmation' by Armoiry and Connock. Heart, 108, (doi: 10.1136/heartjnl-2022-321180)

Lip, S., McCallum, L., Delles, C., McClure, J. D., Guzik, T., Berry, C., Touyz, R., Padmanabhan, S. (2022) Rationale and design for the LOnger-term effects of SARS-CoV-2 INfection on blood Vessels And blood pRessure (LOCHINVAR) Open Heart, 9, (doi: 10.1136/openhrt-2022-002057)

Lithgow, H., Johnston, L., Ho, F. K., Celis- Morales, C., Cobley, J., Raastad, T., Hunter, A. M., Lees, J., Mark, P. B., Quinn, T. J., Gray, S. (2022) Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle damaging resistance exercise in young and older adults – The TAKEOVER study. Research Square, (doi: 10.21203/rs.3.rs-1020009/v1)

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Romaine, S. P. R., Denniff, M., Codd, V., Nath, M., Koekemoer, A., Anker, S. D., Cleland, J. G., Filippatos, G., Levin, D., Metra, M., Mordi, I. R., Ouwerkerk, W., ter Maaten, J. M., van Veldhuisen, D. J., Zannad, F., Ng, L. L., van der Harst, P., Lang, C. C., Voors, A. A., Nelson, C. P., Samani, N. J. (2022) Telomere length is independently associated with all-cause mortality in chronic heart failure. Heart, 108, pp. 124-129. (doi: 10.1136/heartjnl-2020-318654)

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2021

Ralston, M. R., Stevenson, K. S., Mark, P. B., Geddes, C. C. (2021) Clinical factors associated with severe hypophosphataemia after kidney transplant. BMC Nephrology, 22, (doi: 10.1186/s12882-021-02624-3)

Petermann-Rocha, F., Lyall, D. M., Gray, S. R., Gill, J. M.R., Sattar, N., Welsh, P., Quinn, T. J., Stewart, W., Pell, J. P., Ho, F. K., Celis-Morales, C. (2021) Dose-response association between device-measured physical activity and incident dementia: a prospective study from UK Biobank. BMC Medicine, 19, (doi: 10.1186/s12916-021-02172-5)

Crowe, K., Quinn, T. J., Mark, P. B., Findlay, M. D. (2021) “Is it removed during dialysis?”—cognitive dysfunction in advanced kidney failure—a review article. Frontiers in Neurology, 12, (doi: 10.3389/fneur.2021.787370)

Connelly, P. J., Delles, C. (2021) Cardiovascular disease in transgender people: recent research and emerging evidence. Cardiovascular Research, 117, pp. e174-e176. (doi: 10.1093/cvr/cvab288)

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Omar, R., Malfait, F., Van Agtmael, T. (2021) Four decades in the making: collagen III and mechanisms of vascular Ehlers Danlos Syndrome. Matrix Biology Plus, 12, (doi: 10.1016/j.mbplus.2021.100090)

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Dalal, H., Taylor, R. S., Cleland, J. G. (2021) Correspondence to European Heart Journal—Quality of Care and Clinical Outcomes in response to paper by Thomas, M. et al. 2021: Predicting the EQ-5D from the Kansas City Cardiomyopathy Questionnaire (KCCQ) in patients with heart failures. European Heart Journal: Quality of Care and Clinical Outcomes, 7, pp. e7. (doi: 10.1093/ehjqcco/qcab033)

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Dean, A., Van Agtmael, T. (2021) Collagen IV-related diseases and therapies. Springer

Wolsk, E., Kaye, D. M., Komtebedde, J., Shah, S. J., Borlaug, B. A., Burkhoff, D., Kitzman, D. W., Cleland, J. G., Hasenfuß, G., Hassager, C., Møller, J. E., Gustafsson, F. (2021) Determinants and consequences of heart rate and stroke volume response to exercise in patients with heart failure and preserved ejection fraction. European Journal of Heart Failure, 23, pp. 754-764. (doi: 10.1002/ejhf.2146)

Tromp, J., Ouwerkerk, W., Cleland, J. G.F., Angermann, C. E., Dahlstrom, U., Teng, K. T.-H., Bamadhaj, S., Ertl, G., Hassanein, M., Perrone, S. V., Ghandanfar, M., Schweizer, A., Obergfell, A., Filippatos, G., Collins, S. P., Lam, C. S.P., Dickstein, K. (2021) Global differences in burden and treatment of ischemic heart disease in acute heart failure: REPORT-HF. JACC: Heart Failure, 9, pp. 349-359. (doi: 10.1016/j.jchf.2020.12.015)

Mutambudzi, M., Niedzwiedz, C. L., Macdonald, E. B., Leyland, A. H., Mair, F. S., Anderson, J. J., Celis-Morales, C. A., Cleland, J. G., Forbes, J., Gill, J. M.R., Hastie, C. E., Ho, F. K., Jani, B. D., Mackay, D. F., Nicholl, B. I., O'Donnell, C. A., Sattar, N., Welsh, P., Pell, J. P., Katikireddi, S. V., Demou, E. (2021) Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants. Occupational and Environmental Medicine, 78, pp. 307-314. (doi: 10.1136/oemed-2020-106731)

Ferreira, J. P., Claggett, B. L., Liu, J., Desai, A. S., Pfeffer, M. A., Anand, I. S., Van Veldhuisen, D. J., Kober, L., Cleland, J. G.F., Rouleau, J. L., Packer, M., Zile, M. R., Shi, V. C., Lefkowitz, M. P., Shah, S. J., Vardeny, O., Zanannd, F., Solomon, S. D., McMurray, J. J.V. (2021) Serum potassium and outcomes in heart failure with preserved ejection fraction: a post-hoc analysis of the PARAGON-HF trial. European Journal of Heart Failure, 23, pp. 776-784. (doi: 10.1002/ejhf.2134)

Zhang, J., Pellicori, P., Schutte, R., Cleland, J.G. (2021) The association between blood groups and COVID-19 infection: a study from the UK Biobank. Journal of Internal Medicine, 289, pp. 747-748. (doi: 10.1111/joim.13226)

Campbell, E., Petermann-Rocha, F., Welsh, P., Celis-Morales, C., Pell, J. P., Ho, F. K., Gray, S. R. (2021) The effect of exercise on quality of life and activities of daily life in frail older adults: a systematic review of randomised control trials. Experimental Gerontology, 147, (doi: 10.1016/j.exger.2021.111287)

Connelly, P. J., Azizi, Z., Alipour, P., Delles, C., Pilote, L., Raparelli, V. (2021) The importance of gender to understand sex differences in cardiovascular disease. Canadian Journal of Cardiology, 37, pp. 699-710. (doi: 10.1016/j.cjca.2021.02.005)

Pellicori, P., Platz, E., Dauw, J., ter Maaten, J. M., Martens, P., Pivetta, E., Cleland, J. G.F., McMurray, J. J.V., Mullens, W., Solomon, S. D., Zannad, F., Gargani, L., Girerd, N. (2021) Ultrasound imaging of congestion in heart failure – examinations beyond the heart. European Journal of Heart Failure, 23, pp. 703-712. (doi: 10.1002/ejhf.2032)

Coats, A. J. et al. (2021) The management of secondary mitral regurgitation in patients with heart failure: a joint position statement from the Heart Failure Association (HFA), European Association of Cardiovascular Imaging (EACVI), European Heart Rhythm Association (EHRA), and European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. European Heart Journal, 42, pp. 1254-1269. (doi: 10.1093/eurheartj/ehab086)

Mooney, L., Goodyear, C. S., Chandra, T., Kirschner, K., Copland, M., Petrie, M. C., Lang, N. N. (2021) Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure. Clinical Science, 135, pp. 991-1007. (doi: 10.1042/CS20200306)

Vlahou, A. et al. (2021) Data sharing under the General Data Protection Regulation: time to harmonize law and research ethics? Hypertension, 77, pp. 1029-1035. (doi: 10.1161/HYPERTENSIONAHA.120.16340)

Scott, K., Morgan, H. L., Delles, C., Fisher, S., Graham, D., McBride, M. W. (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53, pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020)

van Dorst, D. C.H., Dobbin, S. J.H., Neves, K. B., Herrmann, J., Herrmann, S. M., Versmissen, J., Mathijssen, R. H.J., Danser, A.H. J., Lang, N. N. (2021) Hypertension and prohypertensive antineoplastic therapies in cancer patients. Circulation Research, 128, pp. 1040-1061. (doi: 10.1161/CIRCRESAHA.121.318051)

Ferreira, J. P., Lam, C. S. P., Anker, S. D., Mehra, M. R., van Veldhuisen, D. J., Byra, W. M., La Police, D. A., Cleland, J. G.F., Greenberg, B., Zannad, F. (2021) Plasma D‐dimer concentrations predicting stroke risk and rivaroxaban benefit in patients with heart failure and sinus rhythm: an analysis from the COMMANDER‐HF trial. European Journal of Heart Failure, 23, pp. 648-656. (doi: 10.1002/ejhf.2003)

O’Sullivan, E. D., Lees, J. S., Howie, K. L., Pugh, D., Gillis, K. A., Traynor, J. P., Macintyre, I., Mark, P. B. (2021) Prolonged SARS-CoV-2 viral shedding in patients with chronic kidney disease. Nephrology, 26, pp. 328-332. (doi: 10.1111/nep.13844)

Ferreira, J. P. et al. (2021) Proteomic and mechanistic analysis of spironolactone in patients at risk for HF. JACC: Heart Failure, 9, pp. 268-277. (doi: 10.1016/j.jchf.2020.11.010)

Petermann-Rocha, F., Parra-Soto, S., Gray, S., Anderson, J., Welsh, P., Gill, J., Sattar, N., Ho, F. K., Celis-Morales, C., Pell, J. P. (2021) Vegetarians, fish, poultry and meat-eaters: who has higher risk of CVD incidence and mortality? A prospective study from UK Biobank. European Heart Journal, 42, pp. 1136-1143. (doi: 10.1093/eurheartj/ehaa939)

Uijl, A., Vaartjes, I., Denaxas, S., Hemingway, H., Shah, A. D., Cleland, J., Grobbee, D. E., Hoes, A. W., Asselbergs, F. W., Koudstaal, S. (2021) Temporal trends in heart failure medication prescription in a population-based cohort study. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-043290)

Pellicori, P., Doolub, G., Wong, C. M., Lee, K. S., Mangion, K., Ahmad, M., Berry, C., Squire, I., Lambiase, P., Lyon, A. R., McConnachie, A., Taylor, R. S., Cleland, J. G.F. (2021) COVID-19 and its cardiovascular effects: a systematic review of prevalence studies. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.CD013879)

Smart, N. A., Pearson, M. J., Taylor, R. S., Cleland, J. (2021) Exercise training for heart failure with preserved ejection fraction (ExTraMATCH III): protocol for an individual patient data meta-analysis. Journal of Clinical Exercise Physiology, 10, pp. 3-11. (doi: 10.31189/2165-7629-10.1.3)

Mordi, I. R., Ouwerkerk, W., Anker, S. D., Cleland, J. G., Dickstein, K., Metra, M., Ng, L. L., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Voors, A. A., Lang, C. C. (2021) Heart failure treatment up-titration and outcome and age: an analysis of BIOSTAT-CHF. European Journal of Heart Failure, 23, pp. 436-444. (doi: 10.1002/ejhf.1799)

Ferreira, J. P., Cleland, J. G.F., Lam, C. S.P., van Veldhuisen, D., Byra, W. M., La Police, D. A., Anker, S. D., Mehra, M. R., Leroy, C., Eschwege, V., Toussaint-Hacquard, M., Rossignol, P., Greenberg, B., Zannad, F. (2021) Impact of geographic region on the COMMANDER-HF Trial. JACC: Heart Failure, 9, pp. 201-211. (doi: 10.1016/j.jchf.2020.11.007)

Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2021) Inflammation and salt in young adults: the African-PREDICT study. European Journal of Nutrition, 60, pp. 873-882. (doi: 10.1007/s00394-020-02292-3)

Neves, K. B., Morris, H., Alves-Lopes, R., Muir, K. W., Moreton, F., Delles, C., Montezano, A. C., Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135, pp. 753-773. (doi: 10.1042/CS20201412)

Cameron, A. C., Neves, K. B., White, J., Touyz, R. M., Lang, N. N. (2021) Reply: Cisplatin-associated aortic thrombosis: a review of cases reported to the FDA adverse event reporting system. JACC: CardioOncology, 3, pp. 166. (doi: 10.1016/j.jaccao.2021.01.005)

Sze, S., Pellicori, P., Zhang, J., Weston, J., Clark, A. L. (2021) The impact of malnutrition on short-term morbidity and mortality in ambulatory patients with heart failure. American Journal of Clinical Nutrition, 113, pp. 695-705. (doi: 10.1093/ajcn/nqaa311)

Pearson, R., Asher, J., Jackson, A., Mark, P. B., Shumeyko, V., Clancy, M. J. (2021) Viability assessment and utilization of declined donor kidneys with rhabdomyolysis using ex vivo normothermic perfusion without preimplantation biopsy. American Journal of Transplantation, 21, pp. 1317-1321. (doi: 10.1111/ajt.16329)

Ehteshami-Afshar, S., Mooney, L., Dewan, P., Desai, A. S., Lang, N. N., Lefkowitz, M. P., Petrie, M. C., Rizkala, A. R., Rouleau, J. L., Solomon, S. D., Swedberg, K., Shi, V. C., Zile, M. R., Packer, M., McMurray, J. J.V., Jhund, P. S., Hawkins, N. M. (2021) Clinical characteristics and outcomes of patients with heart failure with reduced ejection fraction and chronic obstructive pulmonary disease: insights from PARADIGM-HF. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.120.019238)

Thom, G., McIntosh, A., Messow, C.-M., Leslie, W. S., Barnes, A. C., Brosnahan, N., McCombie, L., Malkova, D., Al-Mrabeh, A., Zhyzhneuskaya, S., Welsh, P., Sattar, N., Taylor, R., Lean, M. E.J. (2021) Weight loss induced increase in fasting ghrelin concentration is a predictor of weight regain: evidence from the Diabetes Remission Clinical Trial. Diabetes, Obesity and Metabolism, 23, pp. 711-719. (doi: 10.1111/dom.14274)

Lee, M. M.Y. et al. (2021) Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 143, pp. 516-525. (doi: 10.1161/CIRCULATIONAHA.120.052186)

Petrie, M. C., Lee, M. M., Lang, N. N. (2021) EMPEROR-REDUCED reigns while EMPERIAL whimpers. European Heart Journal, 42, pp. 711-714. (doi: 10.1093/eurheartj/ehaa965)

Cleland, J. G.F. et al. (2021) The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart 'OMics' in AGEing (HOMAGE) randomized clinical trial. European Heart Journal, 42, pp. 684-696. (doi: 10.1093/eurheartj/ehaa758)

Rankin, A. J., Mark, P. B. (2021) Cardiac screening prior to renal transplantation – good intentions, rather than good evidence, dictate practice. Kidney International, 99, pp. 306-308. (doi: 10.1016/j.kint.2020.10.043)

Maznyczka, A. M., McCartney, P., Duklas, P., McEntegart, M., Oldroyd, K., Greenwood, J., Muir, D., Chowdhary, S., Gershlick, A. H., Eteiba, H., Cotton, J., Wragg, A., Curzen, N., Tait, R., Macfarlane, P., Welsh, P., Sattar, N., Petrie, M., Ford, I., Fox, K., McConnachie, A., Berry, C. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107, pp. 299-312. (doi: 10.1136/heartjnl-2020-317828)

Felker, G. M. et al. (2021) Effects of a novel nitroxyl donor in acute heart failure: the STAND-UP AHF Study. JACC: Heart Failure, 9, pp. 146-157. (doi: 10.1016/j.jchf.2020.10.012)

Donin, A. S., Nightingale, C. M., Perkin, M. R., Ussher, M., Jebb, S. A., Landberg, R., Welsh, P., Sattar, N., Adab, P., Owen, C. G., Rudnicka, A. R., Cook, D. G., Whincup, P. H. (2021) Evaluating an intervention to increase cereal fiber intake in children: a randomized controlled feasibility trial. Journal of Nutrition, 151, pp. 379-386. (doi: 10.1093/jn/nxaa347)

Halliday, B. P., Owen, R., Gregson, J., Vassiliou, V., Chen, X., Wage, R., Lota, A. S., Khalique, Z., Tayal, U., Hammersley, D. J., Jones, R. E., Baksi, A. J., Cowie, M. R., Cleland, J. G.F., Pennell, D. J., Prasad, S. K. (2021) Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy – insights from TRED‐HF. European Journal of Heart Failure, 23, pp. 293-301. (doi: 10.1002/ejhf.2063)

Docherty, K. F., Campbell, R. T., Brooksbank, K. J.M., Godeseth, R. L., Forsyth, P., McConnachie, A., Roditi, G., Stanley, B., Welsh, P., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2021) Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling. ESC Heart Failure, 8, pp. 129-138. (doi: 10.1002/ehf2.13137)

Al Ozairi, E., Alroudhan, D., Alsaeed, D., Voase, N., Hasan, A., Gill, J. M.R., Sattar, N., Welsh, P., Gray, C. M., Boonpor, J., Celis-Morales, C., Gray, S. R. (2021) Skeletal muscle and metabolic health – how do we increase muscle mass and function in people with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, 106, pp. 309-317. (doi: 10.1210/clinem/dgaa835)

Andonovic, M., Shemilt, R., Sim, M., Traynor, J. P., Shaw, M., Mark, P. B., Puxty, K. A. (2021) Timing of renal replacement therapy for patients with acute kidney injury: a systematic review and meta-analysis. Journal of the Intensive Care Society, 22, pp. 67-77. (doi: 10.1177/1751143720901688)

Connelly, P. J., Clark, A., Touyz, R. M., Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review. Journal of Hypertension, 39, pp. 223-230. (doi: 10.1097/HJH.0000000000002632)

Samuel, N. A., Cuthbert, J. J., Brown, O. I., Kazmi, S., Cleland, J. G.F., Rigby, A. S., Clark, A. L. (2021) Relation between thyroid function and mortality in patients with chronic heart failure. American Journal of Cardiology, 139, pp. 57-63. (doi: 10.1016/j.amjcard.2020.10.034)

Teerlink, J. R. et al. (2021) Cardiac myosin activation with omecamtiv mecarbil in systolic heart failure. New England Journal of Medicine, 384, pp. 105-116. (doi: 10.1056/NEJMoa2025797)

Bekfani, T., Fudim, M., Cleland, J. G.F., Jorbenadze, A., Haehling, S., Lorber, A., Rothman, A. M.‐K., Stein, K., Abraham, W. T., Sievert, H., Anker, S. D. (2021) A current and future outlook on upcoming technologies in the remote monitoring of patients with heart failure. European Journal of Heart Failure, 23, pp. 175-185. (doi: 10.1002/ejhf.2033)

Rutherford, E., Ireland, S., Mangion, K., Stewart, G. A., MacGregor, M., Roditi, G., Woodward, R., Gandy, S. J., Houston, J. G., Jardine, A., Rauchhaus, P., Witham, M. D., Mark, P. D., Struthers, A. D. (2021) A randomized, controlled trial of the effect of allopurinol on left ventricular mass index in hemodialysis patients. Kidney International Reports, 6, pp. 146-155. (doi: 10.1016/j.ekir.2020.10.025)

Moreton, F. C., Cullen, B., Dickie, D. A., Lopez Gonzalez, R., Santosh, C., Delles, C., Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28, pp. 220-228. (doi: 10.1111/ene.14534)

Dobbin, S. J.H., Petrie, M. C., Myles, R. C., Touyz, R. M., Lang, N. N. (2021) Cardiotoxic effects of angiogenesis inhibitors. Clinical Science, 135, pp. 71-100. (doi: 10.1042/CS20200305)

Lees, J. S., Mark, P. B. (2021) Cystatin C to predict renal disease and cardiovascular risk. Nephrology Dialysis Transplantation, 36, pp. 39-41. (doi: 10.1093/ndt/gfaa152)

Davison, B. A., Senger, S., Sama, I. E., Koch, G. G., Mebazaa, A., Dickstein, K., Samani, N. J., Metra, M., Anker, S. D., Cleland, J. G., Ng, L. L., Mordi, I. R., Zannad, F., Filippatos, G. S., Hillege, H. L., Ponikowski, P., Veldhuisen, D. J., Lang, C. C., Meer, P., Núñez, J., Bayés‐Genís, A., Edwards, C., Voors, A. A., Cotter, G. (2021) Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF. European Journal of Heart Failure, 23, pp. 43-57. (doi: 10.1002/ejhf.2077)

Mark, P. B., Del Vecchio, L., Valdivielso, J. M., Malyszko, J. (2021) Same rhythm, different song - approaches to atrial fibrillation management by cardiologists and nephrologists. Clinical Kidney Journal, 14, pp. 9-13. (doi: 10.1093/ckj/sfaa146)

He, T., Melgarejo, J. D., Clark, A. L., Yu, Y.‐L., Thijs, L., Díez, J., López, B., González, A., Cleland, J. G., Schanstra, J. P., Vlahou, A., Latosinska, A., Mischak, H., Staessen, J. A., Zhang, Z.‐Y., Jankowski, V. (2021) Serum and urinary biomarkers of collagen type‐I turnover predict prognosis in patients with heart failure. Clinical and Translational Medicine, 11, (doi: 10.1002/ctm2.267)

Dounousi, E., Tellis, C., Pavlakou, P., Duni, A., Liakopoulos, V., Mark, P. B., Papagianni, A., Tselepis, A. D. (2021) Association between PCSK9 levels and markers of inflammation, oxidative stress, and endothelial dysfunction in a population of nondialysis chronic kidney disease patients. Oxidative Medicine and Cellular Longevity, 2021, (doi: 10.1155/2021/6677012)

Anderson, J. J., Welsh, P., Ho, F. K., Ferguson, L. D., Welsh, C. E., Pellicori, P., Cleland, J. G.F., Forbes, J., Iliodromiti, S., Boyle, J., Lindsay, R., Celis-Morales, C., Gray, S. R., Katikireddi, S. V., Gill, J. M. R., Pell, J. P., Sattar, N. (2021) Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening. BMJ Open Diabetes Research and Care, 9, (doi: 10.1136/bmjdrc-2021-002176)

Small, H. Y., Delles, C. (2021) Letter to the Editor regarding Cunningham et al. 2020. Hypertension in Pregnancy, 40, pp. 133. (doi: 10.1080/10641955.2021.1899201)

McGettrick, M., MacLellan, A., McCaughey, P., Bagot, C., Brewis, M.J., Lang, N.N., Johnson, M.K., Church, A.C. (2021) Pulmonary thromboembolism in hospitalised patients with COVID-19: a retrospective national study of patients managed in critical care and ward environments in Scotland. BMJ Open, 11, (doi: 10.1136/bmjopen-2021-050281)

Shoaib, A., Van Spall, H. G.C., Wu, J., Cleland, J. G.F., McDonagh, T. A., Rashid, M., Mohamed, M. O., Ahmed, F. Z., Deanfield, J., de Belder, M., Gale, C. P., Mamas, M. A. (2021) Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic. European Heart Journal: Quality of Care and Clinical Outcomes, 7, pp. 378-387. (doi: 10.1093/ehjqcco/qcab040)

Shah, P., Pellicori, P., Hanning, I., Zhang, J., Clark, A. L., Bhandari, S. (2021) The effect of digoxin on renal function in patients with heart failure. BMC Nephrology, 22, (doi: 10.1186/s12882-021-02562-0)

Pearson, R., Murray, E., Thomson, P. C., Mark, P. B., Clancy, M. J., Asher, J. (2021) The new UK national kidney allocation scheme with maximized “R4-D4” kidney transplants: better patient-to-graft longevity matching may be at the cost of more resources. Experimental and Clinical Transplantation, 19, pp. 1133-1141. (doi: 10.6002/ect.2021.0129)

2020

Brown, R., Welsh, P., Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events. Open Heart, 7, (doi: 10.1136/openhrt-2020-001396)

Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)

Goncalves Soares, A., Kilpi, F., Fraser, A., Nelson, S. M., Sattar, N., Welsh, P. I., Tilling, K., Lawlor, D. A. (2020) Longitudinal changes in reproductive hormones through the menopause transition in the Avon Longitudinal Study of Parents and Children (ALSPAC) Scientific Reports, 10, (doi: 10.1038/s41598-020-77871-9)

Purcell, C., Daw, P., Kerr, C., Cleland, J., Cowie, A., Dalal, H., Ibbotson, T., Murphy, C., Taylor, R. (2020) Protocol for an implementation study of an evidence-based home cardiac rehabilitation programme for people with heart failure and their caregivers in Scotland (SCOT:REACH-HF) BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040771)

Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116, pp. 2185-2196. (doi: 10.1093/cvr/cvaa209)

Ferguson, A. C., Tank, R., Lyall, L. M., Ward, J., Welsh, P., Celis-Morales, C., McQueenie, R., Strawbridge, R. J., Mackay, D. F., Pell, J. P., Smith, D. J., Sattar, N., Cavanagh, J., Lyall, D. M. (2020) Association of SBP and BMI with cognitive and structural brain phenotypes in UK Biobank. Journal of Hypertension, 38, pp. 2482-2489. (doi: 10.1097/HJH.0000000000002579)

Pellicori, P., Ofstad, A. P., Fitchett, D., Zeller, C., Wanner, C., George, J., Zinman, B., Brueckmann, M., Lindenfeld, J. (2020) Early benefits of empagliflozin in patients with or without heart failure: findings from EMPA-REG OUTCOME. ESC Heart Failure, 7, pp. 3401-3407. (doi: 10.1002/ehf2.12891)

Felker, G. M., Solomon, S. D., McMurray, J. J.V., Cleland, J. G.F., Abbasi, S. A., Malik, F. I., Zhang, H., Globe, G., Teerlink, J. R. (2020) Effects of omecamtiv mecarbil on symptoms and health-related quality of life in patients with chronic heart failure: results from the COSMIC-HF study. Circulation: Heart Failure, 13, (doi: 10.1161/CIRCHEARTFAILURE.120.007814)

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Voors, A. A., van Veldhuisen, D. J., Metra, M., Ponikowski, P., Anker, S. D., Filippatos, G., Lang, C. C., Dickstein, K., Ng, L. L., Samani, N. J., Friedrich, A. W., Rienstra, M., Cleland, J. G.F., ter Maaten, J. M., van Goor, H., Santema, B. T., Ravera, A., Sama, I. E. (2020) Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors. European Heart Journal, 41, pp. 1810-1817. (doi: 10.1093/eurheartj/ehaa373)

Delles, C., Olfert, M. (2020) Electronic cigarettes: how bad are they for your health? Cardiovascular Research, 116, pp. e64-e66. (doi: 10.1093/cvr/cvaa041)

Welsh, C. E., Celis-Morales, C. A., Ho, F. K., Brown, R., Mackay, D. F., Lyall, D. M., Anderson, J. J., Pell, J. P., Gill, J. M.R., Sattar, N., Welsh, P., Gray, S. R. (2020) Grip strength and walking pace and cardiovascular disease risk prediction in 406,834 UK Biobank participants. Mayo Clinic Proceedings, 95, pp. 879-888. (doi: 10.1016/j.mayocp.2019.12.032)

Hayes, S., Forbes, J. F., Celis-Morales, C., Anderson, J., Ferguson, L., Gill, J. M.R., Gray, S., Hastie, C., Iliodromoti, S., Lyall, D., Pellicori, P., Sattar, N., Welsh, C. E., Pell, J. (2020) Association between walking pace and stroke incidence: findings from the UK Biobank prospective cohort study. Stroke, 51, pp. 1388-1395. (doi: 10.1161/STROKEAHA.119.028064)

Tzolos, E., Adamson, P.D., Hall, P.S., MacPherson, I.R., Oikonomidou, O., MacLean, M., Lewis, S.C., McVicars, H., Newby, D.E., Mills, N.L., Lang, N.N., Henriksen, P.A. (2020) Dynamic changes in high-sensitivity cardiac troponin I in response to anthracycline-based chemotherapy. Clinical Oncology, 32, pp. 292-297. (doi: 10.1016/j.clon.2019.11.008)

Stienen, S., Ferreira, J. P., Pitt, B., Cleland, J. G., Pellicori, P., Girerd, N., Rossignol, P., Zannad, F. (2020) Eplerenone prevents an increase in serum carboxy-terminal propeptide of procollagen type I after myocardial infarction complicated by left ventricular dysfunction and/or heart failure. European Journal of Heart Failure, 22, pp. 901-903. (doi: 10.1002/ejhf.1812)

Fudim, M., Dalgaard, F., Al-Khatib, S. M., J. Friedman, D., Lallinger, K., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Gold, M. R., Kutyifa, V., Linde, C., Schaber, D. E., Tang, A., Ali-Ahmed, F., Goldstein, S. A., Kaufman, B., Fortman, R., Davis, J. K., Inoue, L. Y.T., Sanders, G. D. (2020) Future research prioritization in cardiac resynchronization therapy. American Heart Journal, 223, pp. 48-58. (doi: 10.1016/j.ahj.2020.02.011)

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Anderson, J. J., Gray, S. R., Welsh, P., Mackay, D. F., Celis-Morales, C. A., Lyall, D. M., Forbes, J., Sattar, N., Gill, J. M.R., Pell, J. P. (2020) The associations of sugar-sweetened, artificially sweetened and naturally sweet juices with all-cause mortality in 198,285 UK Biobank participants: a prospective cohort study. BMC Medicine, 18, (doi: 10.1186/s12916-020-01554-5)

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Yang, Y., Delalio, L. J., Best, A. K., Macal, E., Milstein, J., Donnelly, I., Miller, A. M., McBride, M., Shu, X., Koval, M., Isakson, B. E., Johnstone, S. R. (2020) Endothelial pannexin 1 channels control inflammation by regulating intracellular calcium. Journal of Immunology, 204, pp. 2995-3007. (doi: 10.4049/jimmunol.1901089)

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White, S. L., Begum, S., Vieira, M. C., Seed, P., Lawlor, D. L., Sattar, N., Nelson, S. M., Welsh, P., Pasupathy, D., Poston, L., on behalf of UPBEAT Consortium, (2020) Metabolic phenotyping by treatment modality in obese women with gestational diabetes suggests diverse pathophysiology: An exploratory study. PLoS ONE, 15, (doi: 10.1371/journal.pone.0230658)

Delles, C., Li, H., Touyz, R. M. (2020) ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19. Clinical Science, 134, pp. 747-750. (doi: 10.1042/CS20200363)

Pandhi, P., Maaten, J. M., Emmens, J. E., Struck, J., Bergmann, A., Cleland, J. G., Givertz, M. M., Metra, M., O'Connor, C. M., Teerlink, J. R., Ponikowski, P., Cotter, G., Davison, B., Veldhuisen, D. J., Voors, A. A. (2020) Clinical value of pre‐discharge bio‐adrenomedullin as a marker of residual congestion and high risk of heart failure hospital readmission. European Journal of Heart Failure, 22, pp. 683-691. (doi: 10.1002/ejhf.1693)

Tofte, N. et al. (2020) Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial. Lancet Diabetes and Endocrinology, 8, pp. 301-312. (doi: 10.1016/S2213-8587(20)30026-7)

Frazier, S., McBride, M. W., Mulvana, H., Graham, D. (2020) From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia. Clinical Science, 134, pp. 1001-1025. (doi: 10.1042/CS20200023)

Macdougall, I. C., Bhandari, S., White, C., Anker, S. D., Farrington, K., Kalra, P. A., Mark, P. B., McMurray, J. J.V., Reid, C., Robertson, M., Tomson, C. R.V., Wheeler, D. C., Winearls, C. G., Ford, I. (2020) Intravenous iron dosing and infection risk in patients on hemodialysis: a prespecified secondary analysis of the PIVOTAL trial. Journal of the American Society of Nephrology, 31, (doi: 10.1681/ASN.2019090972)

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Ho, F. K., Gray, S. R., Welsh, P., Petermann-Rocha, F., Foster, H., Waddell, H., Anderson, J., Lyall, D., Sattar, N., Gill, J. M.R., Mathers, J. C., Pell, J. P., Celis-Morales, C. (2020) Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants. British Medical Journal, 368, (doi: 10.1136/bmj.m688)

Tromp, J., Bamadhaj, S., Cleland, J. G.F., Angermann, C. E., Dahlstrom, U., Ouwerkerk, W., Tay, W. T., Dickstein, K., Ertl, G., Hassanein, M., Hu, D., Perrone, S. V., Ghadanfar, M., Schweizer, A., Obergfell, A., Lam, C. S.P., Filippatos, G., Collins, S. P. (2020) Post-discharge prognosis of patients admitted to hospital for heart failure by world region, and national level of income and income disparity (REPORT-HF): a cohort study. Lancet Global Health, 8, pp. e411-e422. (doi: 10.1016/S2214-109X(20)30004-8)

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Rorth, R., Jhund, P. S., Yilmaz, M. B., Kristensen, S. L., Welsh, P., Desai, A. S., Køber, L., Prescott, M. F., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., Packer, M., McMurray, J. J.V. (2020) Comparison of BNP and NT-proBNP in patients with heart failure and reduced ejection fraction. Circulation: Heart Failure, 13, (doi: 10.1161/CIRCHEARTFAILURE.119.006541)

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Cameron, A. C., Welsh, P., Neves, K. B., Newby, D., Touyz, R. M., Lang, N. (2020) Acute vascular effects of vascular endothelial growth factor inhibition in the forearm arterial circulation. Journal of Hypertension, 38, pp. 257-265. (doi: 10.1097/HJH.0000000000002230)

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Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2020) Distinct inflammatory mediator patterns in young black and white adults: The African-PREDICT study. Cytokine, 126, (doi: 10.1016/j.cyto.2019.154894)

Bégué, C., Mörner, S., Brito, D., Hengstenberg, C., Cleland, J. G.F., Arbustini, E., Galve, E., Wichter, T., Richter, A., Golmard, J.-L., Bernard, M., Dubourg, O., Komajda, M., Charron, P., Isnard, R. (2020) Mid-regional proatrial natriuretic peptide for predicting prognosis in hypertrophic cardiomyopathy. Heart, 106, pp. 196-202. (doi: 10.1136/heartjnl-2019-314826)

Hockings, P., Laustsen, C., Joles, J., Mark, P., Sourbron, S. (2020) Special issue on magnetic resonance imaging biomarkers of renal disease. Magnetic Resonance Materials in Physics, Biology and Medicine, 33, pp. 1-2. (doi: 10.1007/s10334-019-00822-7)

Schlosser, K., Kaur, A., Dayan, N., Stewart, D. J., Pilote, L., Delles, C. (2020) Circulating miR-206 and Wnt-signaling are associated with cardiovascular complications and a history of preeclampsia in women. Clinical Science, 134, pp. 87-101. (doi: 10.1042/CS20190920)

Welsh, C., Welsh, P., Celis Morales, C. A., Mark, P., Mackay, D., Ghouri, N., Ho, F., Ferguson, L. D., Brown, R., Lewsey, J., Cleland, J. G., Gray, S. R., Lyall, D. M., Anderson, J., Jhund, P. S., Pell, J., McGuire, D. K., Gill, J. M.R., Sattar, N. (2020) Glycated hemoglobin, prediabetes and the links to cardiovascular disease: data from UK Biobank. Diabetes Care, 43, pp. 440-445. (doi: 10.2337/dc19-1683)

Filippatos, G., Angermann, C. E., Cleland, J. G.F., Lam, C. S.P., Dahlström, U., Dickstein, K., Ertl, G., Hassanein, M., Hart, K. W., Lindsell, C. J., Perrone, S. V., Guerin, T., Ghadanfar, M., Schweizer, A., Obergfell, A., Collins, S. P. (2020) Global differences in characteristics, precipitants, and initial management of patients presenting with acute heart failure. JAMA Cardiology, 5, pp. 401-410. (doi: 10.1001/jamacardio.2019.5108)

Ferreira, J. P., Ouwerkerk, W., Tromp, J., Ng, L., Dickstein, K., Anker, S., Filippatos, G., Cleland, J. G., Metra, M., van Veldhuisen, D. J., Voors, A. A., Zannad, F. (2020) Cardiovascular and non‐cardiovascular death distinction: the utility of troponin beyond N‐terminal pro‐B‐type natriuretic peptide. Findings from the BIOSTAT‐CHF study. European Journal of Heart Failure, 22, pp. 81-89. (doi: 10.1002/ejhf.1654)

Pellicori, P., Cleland, J. G.F., Clark, A. L. (2020) Chronic obstructive pulmonary disease and heart failure: a breathless conspiracy. Heart Failure Clinics, 16, pp. 33-44. (doi: 10.1016/j.hfc.2019.08.003)

Nikolaidou, T., Samuel, N. A., Marincowitz, C., Fox, D. J., Cleland, J. G.F., Clark, A. L. (2020) Electrocardiographic characteristics in patients with heart failure and normal ejection fraction: a systematic review and meta‐analysis. Annals of Noninvasive Electrocardiology, 25, (doi: 10.1111/anec.12710)

Kobayashi, M., Voors, A. A., Girerd, N., Billotte, M., Anker, S. D., Cleland, J. G., Lang, C. C., Ng, L. L., van Veldhuisen, D. J., Dickstein, K., Metra, M., Duarte, K., Rossignol, P., Zannad, F., Ferreira, J. P. (2020) Heart failure etiologies and clinical factors precipitating for worsening heart failure: Findings from BIOSTAT-CHF. European Journal of Internal Medicine, 71, pp. 62-69. (doi: 10.1016/j.ejim.2019.10.017)

Pellicori, P., Zhang, J., Cuthbert, J., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L., Cleland, J. G.F. (2020) High sensitivity C-reactive protein in chronic heart failure: patient characteristics, phenotypes, and mode of death. Cardiovascular Research, 116, pp. 91-100. (doi: 10.1093/cvr/cvz198)

Pellicori, P., Khan, M. J. I., Graham, F. J., Cleland, J. G.F. (2020) New perspectives and future directions in the treatment of heart failure. Heart Failure Reviews, 25, pp. 147-159. (doi: 10.1007/s10741-019-09829-7)

Cao, T. H., Jones, D. J.L., Voors, A. A., Quinn, P. A., Sandhu, J. K., Chan, D. C.S., Parry, H. M., Mohan, M., Mordi, I. R., Sama, I. E., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Lang, C. C., Ng, L. L. (2020) Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets. European Journal of Heart Failure, 22, pp. 70-80. (doi: 10.1002/ejhf.1608)

Mark, P. B., Papworth, R., Ramparsad, N., Tomlinson, L. A., Sahwney, S., Black, C., McConnachie, A., McCowan, C. (2020) Risk factors associated with biochemically detected and hospitalised acute kidney injury in patients prescribed renin angiotensin system inhibitors. British Journal of Clinical Pharmacology, 86, pp. 121-131. (doi: 10.1111/bcp.14141)

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2019

Kotecha, D., Gill, S. K., Flather, M. D., Holmes, J., Packer, M., Rosano, G., Böhm, M., McMurray, J. J.V., Wikstrand, J., Anker, S. D., van Veldhuisen, D. J., Manzano, L., von Lueder, T. G., Rigby, A. S., Andersson, B., Kjekshus, J., Wedel, H., Ruschitzka, F., Cleland, J. G.F., Damman, K., Redon, J., Coats, A. J.S. (2019) Impact of renal impairment on beta-blocker efficacy in patients with heart failure. Journal of the American College of Cardiology, 74, pp. 2893-2904. (doi: 10.1016/j.jacc.2019.09.059)

Neves, K. B., Harvey, A. P., Moreton, F., Montezano, A. C., Rios, F. J., Alves-Lopes, R., Nguyen Dinh Cat, A., Rocchiccioli, P., Delles, C., Joutel, A., Muir, K., Touyz, R. M. (2019) ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. JCI Insight, 4, (doi: 10.1172/jci.insight.131344)

Mace-Brickman, T., Eddeen, A. B., Carrero, J.-J., Mark, P. B., Molnar, A. O., Lam, N. N., Zimmerman, D., Harel, Z., Sood, M. M. (2019) The risk of stroke and stroke type in patients with atrial fibrillation and chronic kidney disease. Canadian Journal of Kidney Health and Disease, 6, pp. 1-9. (doi: 10.1177/2054358119892372)

Ferguson, L. D., Brown, R., Celis-Morales, C., Welsh, P., Lyall, D. M., Pell, J. P., McInnes, I. B., Siebert, S., Sattar, N. (2019) Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank. Rheumatology, 58, pp. 2137-2142. (doi: 10.1093/rheumatology/kez192)

Connelly, P. J., Freel, E. M., Perry, C., Ewan, J., Touyz, R. M., Currie, G., Delles, C. (2019) Gender-affirming hormone therapy, vascular health and cardiovascular disease in transgender adults. Hypertension, 74, pp. 1266-1274. (doi: 10.1161/HYPERTENSIONAHA.119.13080)

Eastwood, S. V., Chaturvedi, N., Sattar, N., Welsh, P. I., Hughes, A. D., Tillin, T. (2019) Impact of kidney function on cardiovascular risk and mortality: a comparison of South Asian and European cohorts. American Journal of Nephrology, 50, pp. 425-433. (doi: 10.1159/000503873)

Kammer, M., Heinzel, A., Willency, J., Duffin, K., Mayer, G., Simons, K., Gerl, M., Klose, C., Heinze, G., Reindl-Schwaighofer, R., Hu, K., Perco, P., Eder, S., Rosivall, L., Mark, P., Ju, W., Kretzler, M., McCarthy, M., Heerspink, H. J., Wiecek, A., Gomez, M., Oberbauer, R. (2019) Integrative analysis of prognostic biomarkers derived from multiomics panels for the discrimination of chronic kidney disease trajectories in people with type 2 diabetes. Kidney International, 96, pp. 1381-1388. (doi: 10.1016/j.kint.2019.07.025)

Williams, E. H. et al. (2019) Multicentre validation of the CamGFR model for estimated glomerular filtration rate. JNCI Cancer Spectrum, 3, (doi: 10.1093/jncics/pkz068)

Johnson, M. J., Cockayne, S., Currow, D. C., Bell, K., Hicks, K., Fairhurst, C., Gabe, R., Torgerson, D., Jefferson, L., Oxberry, S., Ghosh, J., Hogg, K. J., Murphy, J., Allgar, V., Cleland, J. G.F., Clark, A. L. (2019) Oral modified release morphine for breathlessness in chronic heart failure: a randomised placebo-controlled trial. ESC Heart Failure, 6, pp. 1149-1160. (doi: 10.1002/ehf2.12498)

Cameron, A. C., Lang, N. N., Dominiczak, A. F., Jennings, G. L.R., Batlle, D., Bursztyn, M., Chugh, A. R., Floras, J. S., Taler, S. J., Touyz, R. M., Delles, C. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74, pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343)

Mehra, M. R., Vaduganathan, M., Fu, M., Ferreira, J. P., Anker, S. A., Cleland, J. G.F., Lam, C. S.P., van Veldhuisen, D. J., Byra, W. M., Spiro, T., Deng, H., Zannad, F., Greenberg, B. (2019) A comprehensive analysis of the effects of rivaroxaban on stroke or transient ischaemic attack in patients with heart failure, coronary artery disease, and sinus rhythm: the COMMANDER HF trial. European Heart Journal, 40, pp. 3593-3602. (doi: 10.1093/eurheartj/ehz427)

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2018

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Parsons, T. J., Sartini, C., Welsh, P., Sattar, N., Ash, S., Lennon, L. T., Wannamethee, S. G., Lee, I.-M., Whincup, P. H., Jefferis, B. J. (2018) Objectively measured physical activity and cardiac biomarkers: A cross sectional population based study in older men. International Journal of Cardiology, 254, pp. 322-327. (doi: 10.1016/j.ijcard.2017.11.003)

Gho, J. M.I.H., Schmidt, A. F., Pasea, L., Koudstaal, S., Pujades-Rodriguez, M., Denaxas, S., Shah, A. D., Patel, R. S., Gale, C. P., Hoes, A. W., Cleland, J. G., Hemingway, H., Asselbergs, F. W. (2018) An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors. BMJ Open, 8, (doi: 10.1136/bmjopen-2017-018331)

Taylor, R., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Sattar, N., Welsh, P., Peters, C., Zhyzhneuskaya, S., Hollingsworth, K. G., Al-Mrabeh, A., Rodrigues, A. M., Rehackova, L., Adamson, A. J., Sniehotta, F. F., Mathers, J. C., Ross, H. M., McIlvenna, Y., Kean, S., Ford, I., McConnachie, A., Lean, M. E.J. (2018) Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort. Diabetologia, 61, pp. 589-598. (doi: 10.1007/s00125-017-4503-0)

Stewart, R. A.H., Szalewska, D., Stebbins, A., Al-Khalidi, H. R., Cleland, J. G.H., Rynkiewicz, A., Drazner, M. H., White, H. D., Mark, D. B., Roy, A., Kosevic, D., Rajda, M., Jasinski, M., Leng, C. Y., Tungsubutra, W., Desvigne-Nickens, P., Velazquez, E. J., Petrie, M. C. (2018) Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy. Open Heart, 5, (doi: 10.1136/openhrt-2017-000752)

ter Maaten, J. M., Voors, A. A., Damman, K., van der Meer, P., Anker, S. D., Cleland, J. G.F., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Navis, G., Ng, L., Ouwerkerk, W., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., de Borst, M. H. (2018) Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure. International Journal of Cardiology, 253, pp. 84-90. (doi: 10.1016/j.ijcard.2017.10.010)

Lean, M. E.J. et al. (2018) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet, 391, pp. 541-551. (doi: 10.1016/S0140-6736(17)33102-1)

Conrad, N., Judge, A., Tran, J., Mohseni, H., Hedgecott, D., Crespillo, A. P., Allison, M., Hemingway, H., Cleland, J. G., McMurray, J. J.V., Rahimi, K. (2018) Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals. Lancet, 391, pp. 10-16. (doi: 10.1016/S0140-6736(17)32520-5)

Corcoran, D., Young, R., Cialdella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K.G., Berry, C. (2018) The effects of remote ischaemic preconditioning on coronary artery function in patients with stable coronary artery disease. International Journal of Cardiology, 252, pp. 24-30. (doi: 10.1016/j.ijcard.2017.10.082)

Persu, A. et al. (2018) Blood pressure response to renal denervation is correlated with baseline blood pressure variability: a patient-level meta-analysis. Journal of Hypertension, 36, pp. 221-229. (doi: 10.1097/HJH.0000000000001582)

Currie, G., Delles, C. (2018) Blood pressure targets in the elderly. Journal of Hypertension, 36, pp. 234-236. (doi: 10.1097/HJH.0000000000001576)

Welsh, P. (2018) Correlating changes in metabolic status with arterial health: modest associations but any clinical implications? Hypertension, 71, pp. 227-228. (doi: 10.1161/HYPERTENSIONAHA.117.10595)

Mark, P., Dekkers, I., Blankestijn, P., Leiner, T., Roditi, G. (2018) Letter on 'European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis' Journal of the European Academy of Dermatology and Venereology, 32, pp. e84-e85. (doi: 10.1111/jdv.14774)

Cleland, J. G.F. (2018) Physicians Addicted to Prescribing Aspirin-a Disorder Of Cardiologists (PAPA-DOC) Syndrome: the headache of nonevidence-based medicine for ischemic heart disease? JACC: Heart Failure, 6, pp. 168-171. (doi: 10.1016/j.jchf.2017.11.014)

Nikolaidou, T., Pellicori, P., Zhang, J., Kazmi, S., Goode, K. M., Cleland, J. G., Clark, A. L. (2018) Prevalence, predictors, and prognostic implications of PR interval prolongation in patients with heart failure. Clinical Research in Cardiology, 107, pp. 108-119. (doi: 10.1007/s00392-017-1162-6)

Welsh, P., Kou, L., Yu, C., Anand, I., van Veldhuisen, D. J., Maggioni, A. P., Desai, A. S., Solomon, S. D., Pfeffer, M. A., Cheng, S., Gullestad, L., Aukrust, P., Ueland, T., Swedberg, K., Young, J. B., Kattan, M. W., Sattar, N., McMurray, J. J.V. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. European Journal of Heart Failure, 20, pp. 268-277. (doi: 10.1002/ejhf.988)

Emmens, J. E., Jones, D. J.L., Cao, T. H., Chan, D. C.S., Romaine, S. P.R., Quinn, P. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M., de Boer, R. A., Voors, A. A., Ng, L. L. (2018) Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure. European Journal of Heart Failure, 20, pp. 260-267. (doi: 10.1002/ejhf.1101)

Cotter, G., Metra, M., Davison, B. A., Jondeau, G., Cleland, J. G.F., Bourge, R. C., Milo, O., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2018) Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? European Journal of Heart Failure, 20, pp. 317-322. (doi: 10.1002/ejhf.889)

Stoumpos, S., Lees, J., Welsh, P., Hund, M., Geddes, C. C., Nelson, S. M., Mark, P. B. (2018) The utility of anti-Müllerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation. Reproductive BioMedicine Online, 36, pp. 219-226. (doi: 10.1016/j.rbmo.2017.11.003)

Taylor, A. H.M., Rankin, A. J., McQuarrie, E. P., Freel, M., Homer, N. Z.M., Andrew, R., Jardine, A. G., Mark, P. B. (2018) Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease. Clinical Science, 132, pp. 285-294. (doi: 10.1042/CS20171603)

Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C. C., van der Harst, P., Filippatos, G., Dickstein, K., Cleland, J. G., Anker, S. D., Voors, A. A. (2018) Biomarker-guided versus guideline-based treatment of patients with heart failure: results from BIOSTAT-CHF. Journal of the American College of Cardiology, 71, pp. 386-398. (doi: 10.1016/j.jacc.2017.11.041)

Cleland, J. G.F., Flather, M. D., Altman, D. G., Kotecha, D. (2018) Reply: an incomplete story. Journal of the American College of Cardiology, 71, pp. 105. (doi: 10.1016/j.jacc.2017.10.078)

McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)

Cleland, J. G.F., Bunting, K. V., Flather, M. D., Altman, D. G., Holmes, J., Coats, A. J.S., Manzano, L., McMurray, J. J.V., Ruschitzka, F., van Veldhuisen, D. J., von Lueder, T. G., Böhm, M., Andersson, B., Kjekshus, J., Packer, M., Rigby, A. S., Rosano, G., Wedel, H., Hjalmarson, Å., Wikstrand, J., Kotecha, D. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials. European Heart Journal, 39, pp. 26-35. (doi: 10.1093/eurheartj/ehx564)

Solbu, M. D., Mjøen, G., Mark, P. B., Holdaas, H., Fellström, B., Schmieder, R. E., Zannad, F., Herrington, W. G., Jardine, A. G. (2018) Predictors of atherosclerotic events in patients on haemodialysis: post hoc analyses from the AURORA Study. Nephrology Dialysis Transplantation, 33, pp. 102-112. (doi: 10.1093/ndt/gfw360)

Mark, P. B. (2018) Strategies to manage cardiovascular risk in chronic kidney disease. Nephrology Dialysis Transplantation, 33, pp. 23-25. (doi: 10.1093/ndt/gfx329)

Mangion, K., McDowell, K., Mark, P. B., Rutherford, E. (2018) Characterizing cardiac involvement in chronic kidney disease using CMR—a systematic review. Current Cardiovascular Imaging Reports, 11, (doi: 10.1007/s12410-018-9441-9)

Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study. Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)

Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition. Journal of Clinical Endocrinology and Metabolism, 103, pp. 346-355. (doi: 10.1210/jc.2017-00876)

Stoumpos, S., Hennessy, M., Vesey, A. T., Radjenovic, A., Kasthuri, R., Kingsmore, D. B., Mark, P. B., Roditi, G. (2018) Ferumoxytol-enhanced magnetic resonance angiography for the assessment of potential kidney transplant recipients. European Radiology, 28, pp. 115-123. (doi: 10.1007/s00330-017-4934-5)

Eder, S., Leierer, J., Kerschbaum, J., Rosivall, L., Wiecek, A., de Zeeuw, D., Mark, P. B., Heinze, G., Rossing, P., Heerspink, H. L., Mayer, G. (2018) A prospective cohort study in patients with type 2 diabetes mellitus for validation of biomarkers (PROVALID) –study design and baseline characteristics. Kidney and Blood Pressure Research, 43, pp. 181-190. (doi: 10.1159/000487500)

Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)

2017

Celis-Morales, C. A., Petermann, F., Hui, L., Lyall, D. M., Iliodromiti, S., McLaren, J., Anderson, J., Welsh, P., Mackay, D. F., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40, pp. 1710-1718. (doi: 10.2337/dc17-0921)

Kaye, D. M., Silvestry, F. E., Gustafsson, F., Cleland, J. G., van Veldhuisen, D. J., Ponikowski, P., Komtebedde, J., Nanayakkara, S., Burkhoff, D., Shah, S. J. (2017) Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European Journal of Heart Failure, 19, pp. 1690-1697. (doi: 10.1002/ejhf.930)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)

Krochmal, M., Kontostathi, G., Magalhães, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J.-L., Denis, C., Zoidakis, J., Zürbig, P., Delles, C., Schanstra, J. P., Mischak, H., Vlahou, A. (2017) Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy. Scientific Reports, 7, (doi: 10.1038/s41598-017-15359-9)

Vieira, M. C., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. (2017) Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study. BMC Medicine, 15, (doi: 10.1186/s12916-017-0956-8)

Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P., Sattar, N., Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7, (doi: 10.1136/bmjopen-2017-018264)

Shah, P., Pellicori, P., Macnamara, A., Urbinati, A., Clark, A. L. (2017) Is swimming safe in heart failure? A systematic review. Cardiology in Review, 25, pp. 321-325. (doi: 10.1097/CRD.0000000000000154)

Rutherford, E., Stewart, G., Houston, J. G., Jardine, A. G., Mark, P. B., Struthers, A. D. (2017) An open-label dose-finding study of allopurinol to target defined reduction in urate levels in hemodialysis patients. Journal of Clinical Pharmacology, 57, pp. 1409-1414. (doi: 10.1002/jcph.939)

Mary, S., Kulkarni, M. J., Mehendale, S. S., Joshi, S. R., Giri, A. P. (2017) Differential accumulation of vimentin fragments in preeclamptic placenta. Cytoskeleton, 74, pp. 420-425. (doi: 10.1002/cm.21390)

Pontillo, C. et al. (2017) Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker. Kidney International Reports, 2, pp. 1066-1075. (doi: 10.1016/j.ekir.2017.06.004)

Welsh, P., Grassia, G., Botha, S., Sattar, N., Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174, pp. 3898-3913. (doi: 10.1111/bph.13818)

Schmieder, R. E., Wagner, F., Mayr, M., Delles, C., Ott, C., Keicher, C., Hrabak-Paar, M., Heye, T., Aichner, S., Khder, Y., Yates, D., Albrecht, D., Langenickel, T., Freyhardt, P., Janka, R., Bremerich, J. (2017) The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study. European Heart Journal, 38, pp. 3308-3317. (doi: 10.1093/eurheartj/ehx525)

Rutherford, E., Mangion, K., Mccomb, C., Bell, E., Cockburn, S., Talle, M., Roditi, G., Welsh, P., Woodward, R., Radjenovic, A., Struthers, A. D., Jardine, A., Berry, C., Patel, R. K., Mark, P. B. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, (doi: 10.1038/s41598-017-14481-y)

Bayes-Genis, A., Núñez, J., Zannad, F., Ferreira, J. P., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Lang, C. C., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Metra, M., Lupón, J., Voors, A. A. (2017) The PCSK9-LDL receptor axis and outcomes in heart failure: BIOSTAT-CHF subanalysis. Journal of the American College of Cardiology, 70, pp. 2128-2136. (doi: 10.1016/j.jacc.2017.08.057)

Kohli-Lynch, C.N., Boyd, K., Briggs, A., Delles, C. (2017) A Framework for the Cost-Effectiveness Analysis of Novel Biomarker Testing in Cardiovascular Disease. (doi: 10.1016/j.jval.2017.08.040)

Sharma, A., Demissei, B. G., Tromp, J., Hillege, H. L., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Davison, B. A., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van Veldhuisen, D. J., Cotter, G., Ezekowitz, J. A., Khan, M. A.F., Voors, A. A. (2017) A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure. European Journal of Heart Failure, 19, pp. 1310-1320. (doi: 10.1002/ejhf.912)

Stevens, K., Denby, L., Patel, R. K., Mark, P. B., Kettlewell, S., Smith, G. L., Clancy, M. J., Delles, C., Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32, pp. 1617-1627. (doi: 10.1093/ndt/gfw252)

White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. (2017) Metabolic profiling of gestational diabetes in obese women during pregnancy. Diabetologia, 60, pp. 1903-1912. (doi: 10.1007/s00125-017-4380-6)

Ferreira, J. P., Rossignol, P., Machu, J.-L., Sharma, A., Girerd, N., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ter Maaten, J., Metra, M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Voors, A., Zannad, F. (2017) Mineralocorticoid receptor antagonist pattern of use in heart failure with reduced ejection fraction: findings from BIOSTAT-CHF. European Journal of Heart Failure, 19, pp. 1284-1293. (doi: 10.1002/ejhf.900)

Nassif, M. E., Tang, Y., Cleland, J. G.F., Abraham, W. T., Linde, C., Gold, M. R., Young, J. B., Daubert, J. C., Sherfesee, L., Schaber, D., Tang, A. S.L., Jones, P. G., Arnold, S. V., Spertus, J. A. (2017) Precision medicine for cardiac resynchronization: predicting quality of life benefits for individual patients-an analysis from 5 clinical trials. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004111)

Cleland, J. G.F., Halliday, B. P., Prasad, S. K. (2017) Selecting patients with nonischemic dilated cardiomyopathy for ICDs. Journal of the American College of Cardiology, 70, pp. 1228-1231. (doi: 10.1016/j.jacc.2017.07.748)

Noh, R. M., Venkatasubramanian, S., Daga, S., Langrish, J., Mills, N. L., Lang, N. N., Hoffmann, E., Waterhouse, B., Newby, D. E., Frier, B. M. (2017) Cardiometabolic effects of a novel SIRT1 activator, SRT2104, in people with type 2 diabetes mellitus. Open Heart, 4, (doi: 10.1136/openhrt-2017-000647)

Fröhlich, H., Torres, L., Täger, T., Schellberg, D., Corletto, A., Kazmi, S., Goode, K., Grundtvig, M., Hole, T., Katus, H. A., Cleland, J. G.F., Atar, D., Clark, A. L., Agewall, S., Frankenstein, L. (2017) Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure. Clinical Research in Cardiology, 106, pp. 711-721. (doi: 10.1007/s00392-017-1115-0)

Wannamethee, S. G., Welsh, P., Papacosta, O., Ellins, E. A., Halcox, J. P.J., Whincup, P. H., Sattar, N. (2017) Circulating soluble receptor for advanced glycation end product: cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis, 264, pp. 36-43. (doi: 10.1016/j.atherosclerosis.2017.07.008)

Price, A. H., Weir, C. J., Welsh, P., McLachlan, S., Strachan, M. W.J., Sattar, N., Price, J. F. (2017) Comparison of non-traditional biomarkers, and combinations of biomarkers, for vascular risk prediction in people with type 2 diabetes: The Edinburgh Type 2 Diabetes Study. Atherosclerosis, 264, pp. 67-73. (doi: 10.1016/j.atherosclerosis.2017.07.009)

Cleland, J. G.F. (2017) Does aspirin detract from the benefits of mineralocorticoid receptor antagonists in patients with heart failure and a reduced left ventricular ejection fraction? Probably! European Journal of Heart Failure, 19, pp. 1086-1088. (doi: 10.1002/ejhf.697)

Koudstaal, S., Pujades-Rodriguez, M., Denaxas, S., Gho, J. M.I.H., Shah, A. D., Yu, N., Patel, R. S., Gale, C. P., Hoes, A. W., Cleland, J. G.F., Asselbergs, F. W., Hemingway, H. (2017) Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people. European Journal of Heart Failure, 19, pp. 1119-1127. (doi: 10.1002/ejhf.709)

Sanders, M. F., van Doormaal, P. J., Beeftink, M. M.A., Bots, M. L., Fadl Elmula, F. E. M., Habets, J., Hammer, F., Hoffmann, P., Jacobs, L., Mark, P. B., Persu, A., Renkin, J., Roditi, G., Spiering, W., Staessen, J. A., Taylor, A. H., Verloop, W. L., Vink, E. E., Vonken, E.-J., Voskuil, M., Leiner, T., Blankestijn, P. J. (2017) Renal artery and parenchymal changes after renal denervation: assessment by magnetic resonance angiography. European Radiology, 27, pp. 3934-3941. (doi: 10.1007/s00330-017-4770-7)

Krochmal, M., Cisek, K., Filip, S., Markoska, K., Orange, C., Zoidakis, J., Gakiopoulou, C., Spasovski, G., Mischak, H., Delles, C., Vlahou, A., Jankowski, J. (2017) Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. Scientific Reports, 7, (doi: 10.1038/s41598-017-09393-w)

Willeit, P., Welsh, P., Evans, J. D.W., Tschiderer, L., Boachie, C., Jukema, J. W., Ford, I., Trompet, S., Stott, D. J., Kearney, P. M., Mooijaart, S. P., Kiechl, S., Di Angelantonio, E., Sattar, N. (2017) High-sensitivity cardiac troponin concentration and risk of first-ever cardiovascular outcomes: literature-based meta-analysis involving 154,052 participants. Journal of the American College of Cardiology, 70, pp. 558-568. (doi: 10.1016/j.jacc.2017.05.062)

Bhat, S., Mary, S., Giri, A. P., Kulkarni, M. J. (2017) Advanced glycation end products (AGEs) in diabetic complications. Springer

Jenks, S. J., Conway, B. R., McLachlan, S., Teoh, W. L., Williamson, R. M., Webb, D. J., Welsh, P., Sattar, N., Strachan, M. W.J., Price, J. F. (2017) Cardiovascular disease biomarkers are associated with declining renal function in type 2 diabetes. Diabetologia, 60, pp. 1400-1408. (doi: 10.1007/s00125-017-4297-0)

Gimpelewicz, C., Metra, M., Cleland, J. G.F., Szecsödy, P., Chang Wun, C.-C., Boer-Martins, L., Cotter, G., Davison, B. A., Felker, G. M., Filippatos, G., Greenberg, B. H., Pang, P., Ponikowski, P., Severin, T., Voors, A. A., Teerlink, J. R. (2017) Effects of serelaxin on the outcome of patients with or without substantial peripheral edema: a subgroup analysis from the RELAX-AHF trial. American Heart Journal, 190, pp. 113-122. (doi: 10.1016/j.ahj.2017.05.012)

Currie, G., Delles, C. (2017) Healthy vascular ageing. Hypertension, 70, pp. 229-231. (doi: 10.1161/HYPERTENSIONAHA.117.09122)

Small, H. Y., Cornelius, D. C., Guzik, T. J., Delles, C. (2017) Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy. Placenta, 56, pp. 59-64. (doi: 10.1016/j.placenta.2017.03.003)

Zhang, Z.‐Y., Ravassa, S., Nkuipou‐Kenfack, E., Yang, W.-Y., Kerr, S. M., Koeck, T., Campbell, A., Kuznetsova, T., Mischak, H., Padmanabhan, S., Dominiczak, A. F., Delles, C., Staessen, J. A. (2017) Novel urinary peptidomic classifier predicts incident heart failure. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.005432)

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Emdin, C. A., Hsiao, A. J., Kiran, A., Conrad, N., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., McMurray, J. J.V., Cleland, J. G.F., Dargie, H., Hardman, S., McDonagh, T., Rahimi, K. (2017) Referral for specialist follow-up and its association with post-discharge mortality among patients with systolic heart failure (from the National Heart Failure Audit for England and Wales) American Journal of Cardiology, 119, pp. 440-444. (doi: 10.1016/j.amjcard.2016.10.021)

Koh-Tan, H.H. C., Dashti, M., Wang, T., Beattie, W., Mcclure, J., Young, B., Dominiczak, A. F., McBride, M. W., Graham, D. (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35, pp. 319-329. (doi: 10.1097/HJH.0000000000001155)

Gastelurrutia, P., Lupón, J., Domingo, M., Stut, W., Dovancescu, S., Cleland, J., Frankenstein, L., Bayes-Genis, A. (2017) Potential role for clinical calibration to increase engagement with and application of home telemonitoring: a report from the HeartCycle programme. ESC Heart Failure, 4, pp. 66-70. (doi: 10.1002/ehf2.12104)

Zhang, J., Dierckx, R., Mohee, K., Clark, A. L., Cleland, J. G.F. (2017) Xanthine oxidase inhibition for the treatment of cardiovascular disease: an updated systematic review and meta-analysis. ESC Heart Failure, 4, pp. 40-45. (doi: 10.1002/ehf2.12112)

Delles, C., Husi, H. (2017) Systems biology approach in hypertension research. Springer

Tsiropoulou, S., McBride, M., Padmanabhan, S. (2017) Urine metabolomics in hypertension research. Springer

Mancini, S. J., White, A. D., Bijland, S., Rutherford, C., Graham, D., Richter, E. A., Viollet, B., Touyz, R. M., Palmer, T. M., Salt, I. P. (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010)

Streng, K. W., ter Maaten, J. M., Cleland, J. G.F., O’Connor, C. M., Davison, B. A., Metra, M., Givertz, M. M., Teerlink, J. R., Ponikowski, P., Bloomfield, D. M., Dittrich, H. C., Hillege, H. L., van Veldhuisen, D. J., Voors, A. A., van der Meer, P. (2017) Associations of body mass index with laboratory and biomarkers in patients with acute heart failure. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.116.003350)

Stoumpos, S., Mark, P. B., McQuarrie, E. P., Traynor, J. P., Geddes, C. C. (2017) Continued monitoring of acute kidney injury survivors might not be necessary in those regaining an estimated glomerular filtration rate > 60 mL/min at 1 year. Nephrology Dialysis Transplantation, 32, pp. 81-88. (doi: 10.1093/ndt/gfw413)

Rutherford, E., Weir-McCall, J. R., Patel, R. K., Houston, J. G., Roditi, G., Struthers, A. D., Jardine, A. G., Mark, P. B. (2017) Research cardiac magnetic resonance imaging in end stage renal disease - incidence, significance and implications of unexpected incidental findings. European Radiology, 27, pp. 315-324. (doi: 10.1007/s00330-016-4288-4)

Tromp, J., ter Maaten, J., Damman, K., O’Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., van der Wal, M. H.L., Jaarsma, T., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2017) Serum potassium levels and outcome in acute heart failure (data from the PROTECT and COACH trials) American Journal of Cardiology, 119, pp. 290-296. (doi: 10.1016/j.amjcard.2016.09.038)

Cameron, A. C., Lang, N. N., Touyz, R. M. (2017) Cardiovascular complications from cancer therapy: hypertension-focus on vascular endothelial growth factor inhibitors. Elesvier

Delles, C., Vanholder, R. (2017) Chronic kidney disease. Clinical Science, 131, pp. 225-226. (doi: 10.1042/CS20160624)

Celis-Morales, C., Lyall, D. M., Gray, S., Steell, L., Anderson, J., Iliodromiti, S., Welsh, P., Guo, Y., Petermann, F., Mackay, D. F., Bailey, M. E.S., Pell, J., Gill, J. M.R., Sattar, N. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi: 10.1038/ijo.2017.169)

Cuthbert, J. J., Pellicori, P., Clark, A. L. (2017) Interatrial shunt devices for heart failure with normal ejection fraction: a technology update. Medical Devices: Evidence and Research, 10, pp. 123-132. (doi: 10.2147/mder.s113105)

Arain, F., Gullestad, L., Nymo, S., Kjekshus, J., Cleland, J. G.F., Michelsen, A., McMurray, J. J.V., Wikstrand, J., Aukrust, P., Ueland, T. (2017) Low YKL-40 in Chronic Heart Failure may predict beneficial effects of statins: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) Biomarkers, 22, pp. 261-267. (doi: 10.1080/1354750X.2016.1204003)

Pellicori, P., Carubelli, V. (2017) Terapia diuretica nell’insufficienza cardiaca cronica: evidenze, esperienze, prospettive = Diuretic treatment in patients with chronic heart failure: evidences, experiences, and current perspectives. Giornale Italiano di Cardiologia, 18, pp. 129-138. (doi: 10.1714/2663.27298)

Pellicori, P., Salekin, D., Pan, D., Clark, A. L. (2017) This patient is not breathing properly: is this COPD, heart failure, or neither? Expert Review of Cardiovascular Therapy, 15, pp. 389-396. (doi: 10.1080/14779072.2017.1317592)

2016

Torabi, A., Cleland, J. G.F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., Thackray, S., Hoye, A., Alamgir, F., Goode, K., Rigby, A., Clark, A. L. (2016) Influence of case definition on incidence and outcome of acute coronary syndromes. Open Heart, 3, (doi: 10.1136/openhrt-2016-000487)

Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Solomon, S. D., Adams, Jr., K. F., Cleland, J. G.F., Ezekowitz, J. A., Goudev, A., Macdonald, P., Metra, M., Mitrovic, V., Ponikowski, P., Serpytis, P., Spinar, J., Tomcsányi, J., Vandekerckhove, H. J., Voors, A. A., Monsalvo, M. L., Johnston, J., Malik, F. I., Honarpour, N. (2016) Chronic oral study of myosin activation to increase contractility in heart failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. Lancet, 388, pp. 2895-2903. (doi: 10.1016/S0140-6736(16)32049-9)

White, S. L., Lawlor, D. A., Briley, A. L., Godfrey, K. M., Nelson, S. M., Oteng-Ntim, E., Robson, S. C., Sattar, N., Seed, P. T., Vieira, M. C., Welsh, P., Whitworth, M., Poston, L., Pasupathy, D. (2016) Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167846)

Vegter, E. L., Schmitter, D., Hagemeijer, Y., Ovchinnikova, E. S., van der Harst, P., Teerlink, J. R., O'Connor, C. M., Metra, M., Davison, B. A., Bloomfield, D., Cotter, G., Cleland, J. G.F., Givertz, M. M., Ponikowski, P., van Veldhuisen, D. J., van der Meer, P., Berezikov, E., Voors, A. A., Khan, M. A.F. (2016) Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure. International Journal of Cardiology, 224, pp. 231-239. (doi: 10.1016/j.ijcard.2016.09.010)

Rebollo-Mesa, I. et al. (2016) Biomarkers of tolerance in kidney transplantation - are we predicting tolerance or response to immunosuppressive treatment? American Journal of Transplantation, 16, pp. 3443-3457. (doi: 10.1111/ajt.13932)

Pellicori, P., Cleland, J. G.F., Zhang, J., Kallvikbacka-Bennett, A., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L. (2016) Cardiac dysfunction, congestion and loop diuretics: their relationship to prognosis in heart failure. Cardiovascular Drugs and Therapy, 30, pp. 599-609. (doi: 10.1007/s10557-016-6697-7)

Verdura, E., Hervé, D., Bergametti, F., Jacquet, C., Morvan, T., Prieto-Morin, C., Mackowiak, A., Manchon, E., Hosseini, H., Cordonnier, C., Girard-Buttaz, I., Rosenstingl, S., Hagel, C., Kuhlenbaümer, G., Leca-Radu, E., Goux, D., Fleming, L., Van Agtmael, T., Chabriat, H., Chapon, F., Tournier-Lasserve, E. (2016) Disruption of a miR-29 binding site leading to COL4A1 upregulation causes pontine autosomal dominant microangiopathy with leukoencephalopathy. Annals of Neurology, 80, pp. 741-753. (doi: 10.1002/ana.24782)

Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2016) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Heart, 103, pp. 255-257. (doi: 10.1136/heartjnl-2015-309191)

Demissei, B. G., Postmus, D., Liu, L. C.Y., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B. A., Edwards, C., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Voors, A. A., Hillege, H. L. (2016) Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure — Post-hoc analysis of the PROTECT trial. International Journal of Cardiology, 223, pp. 967-975. (doi: 10.1016/j.ijcard.2016.08.271)

Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J.V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Rocca, H. P. B.-L., Delles, C., Heymans, S., Sattar, N., Jukema, J. W., Cleland, J. G.F., Zannad, F., Rossignol, P. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, (doi: 10.1186/s12916-016-0731-2)

Rutherford, C., Speirs, C., Williams, J. J.L., Ewart, M.-A., Mancini, S. J., Hawley, S. A., Delles, C., Viollet, B., Costa-Pereira, A. P., Baillie, G. S., Salt, I. P., Palmer, T. M. (2016) Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. Science Signaling, 9, (doi: 10.1126/scisignal.aaf8566)

Bekfani, T., Pellicori, P., Morris, D. A., Ebner, N., Valentova, M., Steinbeck, L., Wachter, R., Elsner, S., Sliziuk, V., Schefold, J. C., Sandek, A., Doehner, W., Cleland, J. G.F., Lainscak, M., Anker, S. D., von Haehling, S. (2016) Sarcopenia in patients with heart failure with preserved ejection fraction: impact on muscle strength, exercise capacity and quality of life. International Journal of Cardiology, 222, pp. 41-46. (doi: 10.1016/j.ijcard.2016.07.135)

Welsh, P., Tuckwell, K., McInnes, I. B., Sattar, N. (2016) Effect of IL-6 receptor blockade on high-sensitivity troponin T and NT-proBNP in rheumatoid arthritis. Atherosclerosis, 254, pp. 167-171. (doi: 10.1016/j.atherosclerosis.2016.10.016)

Preiss, D., Rankin, N., Welsh, P., Holman, R.R., Kangas, A.J., Soininen, P., Würtz, P., Ala-Korpela, M., Sattar, N. (2016) Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study. Diabetic Medicine, 33, pp. 1569-1574. (doi: 10.1111/dme.13097)

Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D., Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68, pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933)

Currie, G., Delles, C. (2016) Urinary proteomics for diagnosis and monitoring of diabetic nephropathy. Current Diabetes Reports, 16, (doi: 10.1007/s11892-016-0798-3)

Pandit, S. V., Workman, A. (2016) Atrial electrophysiological remodeling and fibrillation in heart failure. Clinical Medicine Insights: Cardiology, 10, pp. 41-46. (doi: 10.4137/CMC.S39713)

Tromp, J., Meyer, S., Mentz, R. J., O'Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2016) Acute heart failure in the young: clinical characteristics and biomarker profiles. International Journal of Cardiology, 221, pp. 1067-1072. (doi: 10.1016/j.ijcard.2016.06.339)

Sokoreli, I., de Vries, J.J.G., Riistama, J.M., Pauws, S.C., Steyerberg, E.W., Tesanovic, A., Geleijnse, G., Goode, K.M., Crundall-Goode, A., Kazmi, S., Cleland, J.G.F., Clark, A.L. (2016) Depression as an independent prognostic factor for all-cause mortality after a hospital admission for worsening heart failure. International Journal of Cardiology, 220, pp. 202-207. (doi: 10.1016/j.ijcard.2016.06.068)

Rutherford, E., Talle, M. A., Mangion, K., Bell, E., Rauhalammi, S. M., Roditi, G., McComb, C., Radjenovic, A., Welsh, P., Woodward, R., Struthers, A. D., Jardine, A. G., Patel, R. K., Berry, C., Mark, P. B. (2016) Definition of myocardial tissue abnormalities in end stage renal failure with cardiac magnetic resonance imaging using T1 mapping. Kidney International, 90, pp. 845-852. (doi: 10.1016/j.kint.2016.06.014)

Cameron, A. C., Lang, N. N., Touyz, R. M. (2016) Drug treatment of hypertension: focus on vascular health. Drugs, 76, pp. 1529-1550. (doi: 10.1007/s40265-016-0642-8)

Herrington, W. G., Emberson, J., Mihaylova, B., Blackwell, L., Reith, C., Solbu, M. D., Mark, P. B., Fellström, B., Jardine, A. G., Wanner, C., Holdaas, H., Fulcher, J., Haynes, R., Landray, M. J., Keech, A., Simes, J., Collins, R., Baigent, C. (2016) Impact of renal function on the effects of LDL cholesterol lowering with statin-based regimens: a meta-analysis of individual participant data from 28 randomised trials. Lancet Diabetes and Endocrinology, 4, pp. 829-839. (doi: 10.1016/S2213-8587(16)30156-5)

Willeit, P. et al. (2016) Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis. Lancet Diabetes and Endocrinology, 4, pp. 840-849. (doi: 10.1016/S2213-8587(16)30196-6)

Cleland, J. G.F., Pellicori, P. (2016) PARADIGM-HF: does dose matter? European Journal of Heart Failure, 18, pp. 1235-1237. (doi: 10.1002/ejhf.634)

Cotter, G., Davison, B. A., Milo, O., Bourge, R. C., Cleland, J. G.F., Jondeau, G., Krum, H., O'Connor, C. M., Metra, M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2016) Predictors and associations with outcomes of length of hospital stay in patients with acute heart failure: results from VERITAS. Journal of Cardiac Failure, 22, pp. 815-822. (doi: 10.1016/j.cardfail.2015.12.017)

Joseph, A. C., Prapa, M., Pellicori, P., Mabote, T., Nasir, M., Clark, A. L. (2016) Tachycardia-induced cardiomyopathy in pregnancy. Journal of Cardiovascular Medicine, 17, pp. 762-766. (doi: 10.2459/jcm.0000000000000209)

Currie, G., Matt, P., Delles, C. (2016) Clinical cardiovascular proteomics. Springer

Currie, G., Taylor, A. H.M., Fujita, T., Ohtsu, H., Lindhart, M., Rossing, P., Boesby, L., Edwards, N. C., Ferro, C. J., Townend, J. N., van den Meiracker, A. H., Saklayen, M. G., Oveisi, S., Jardine, A. G., Delles, C., Preiss, D. J., Mark, P. B. (2016) Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis. BMC Nephrology, 17, (doi: 10.1186/s12882-016-0337-0)

Stirrat, C. G., Venkatasubramanian, S., Pawade, T., Mitchell, A. J., Shah, A. S., Lang, N. N., Newby, D. E. (2016) Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure. British Journal of Clinical Pharmacology, 82, pp. 974-982. (doi: 10.1111/bcp.13033)

Wijsman, L. W., de Craen, A. J.M., Trompet, S., Sabayan, B., Muller, M., Stott, D. J., Ford, I., Welsh, P., Westendorp, R. G.J., Jukema, J. W., Sattar, N., Mooijaart, S. P. (2016) High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk. European Journal of Preventive Cardiology, 23, pp. 1383-1392. (doi: 10.1177/2047487316632364)

Morgan, H., Small, H.Y., Beattie, E., McBride, M.W., Graham, D. (2016) [OP.5D.02] Transcriptomic changes in early pregnancy-associated uterine artery remodelling in stroke prone spontaneously hypertensive rat. Journal of Hypertension, 34, pp. e63-e63. (doi: 10.1097/01.hjh.0000491501.79443.05)

ter Maaten, J. M., Damman, K., Hanberg, J. S., Givertz, M. M., Metra, M., O’Connor, C. M., Teerlink, J. R., Ponikowski, P., Cotter, G., Davison, B., Cleland, J. G.F., Bloomfield, D. M., Hillege, H. L., van Veldhuisen, D. J., Voors, A. A., Testani, J. M. (2016) Hypochloremia, diuretic resistance, and outcome in patients with acute heart failure. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003109)

Carberry, J., Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Remote zone extracellular volume and left ventricular remodeling in survivors of st-elevation myocardial infarction. Hypertension, 68, pp. 385-391. (doi: 10.1161/HYPERTENSIONAHA.116.07222)

Bhattacharyya, S., Mittal, T., Abayalingam, M., Kabir, T., Dalby, M., Cleland, J. G.F., Baltabaeva, A., Rahman Haley, S. (2016) Classification of aortic stenosis by flow and gradient patterns provides insights into the pathophysiology of disease. Angiology, 67, pp. 664-669. (doi: 10.1177/0003319715611804)

Mordi, I., Mordi, N., Delles, C., Tzemos, N. (2016) Endothelial dysfunction in human essential hypertension. Journal of Hypertension, 34, pp. 1464-1472. (doi: 10.1097/hjh.0000000000000965)

Fröhlich, H., Nelges, C., Täger, T., Schwenger, V., Cebola, R., Schnorbach, J., Goode, K. M., Kazmi, S., Katus, H. A., Cleland, J. G.F., Clark, A. L., Frankenstein, L. (2016) Long-term changes of renal function in relation to ace inhibitor/angiotensin receptor blocker dosing in patients with heart failure and chronic kidney disease. American Heart Journal, 178, pp. 28-36. (doi: 10.1016/j.ahj.2016.03.024)

Preiss, D., Welsh, P., Sattar, N. (2016) Metformin therapy and circulating NT-proBNP levels: the CAMERA trial. Diabetes Care, 39, pp. e114-e115. (doi: 10.2337/dc16-0887)

Davison, B. A., Metra, M., Senger, S., Edwards, C., Milo, O., Bloomfield, D. M., Cleland, J. G., Dittrich, H. C., Givertz, M. M., O'Connor, C. M., Massie, B. M., Ponikowski, P., Teerlink, J. R., Voors, A. A., Cotter, G. (2016) Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality. European Journal of Heart Failure, 18, pp. 1041-1050. (doi: 10.1002/ejhf.540)

Cleland, J. G.F., Zhang, J., Pellicori, P., Dicken, B., Dierckx, R., Shoaib, A., Wong, K., Rigby, A., Goode, K., Clark, A. L. (2016) Prevalence and outcomes of anemia and hematinic deficiencies in patients with chronic heart failure. JAMA Cardiology, 1, pp. 539-547. (doi: 10.1001/jamacardio.2016.1161)

Findlay, M. D., Thomson, P. C., Macisaac, R., Jardine, A. G., Patel, R. K., Stevens, K. K., Rutherford, E., Clancy, M., Geddes, C. C., Dawson, J., Mark, P. B. (2016) Risk factors and outcome of stroke in renal transplant recipients. Clinical Transplantation, 30, pp. 918-924. (doi: 10.1111/ctr.12765)

Biegus, J., Hillege, H. L., Postmus, D., Valente, M. A.E., Bloomfield, D. M., Cleland, J. G.F., Cotter, G., Davison, B. A., Dittrich, H. C., Fiuzat, M., Givertz, M. M., Massie, B. M., Metra, M., Teerlink, J. R., Voors, A. A., O'Connor, C. M., Ponikowski, P. (2016) Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study. European Journal of Heart Failure, 18, pp. 830-839. (doi: 10.1002/ejhf.532)

Khamis, R. Y., Hughes, A. D., Caga-Anan, M., Chang, C. L., Boyle, J. J., Kojima, C., Welsh, P., Sattar, N., Johns, M., Sever, P., Mayet, J., Haskard, D. O. (2016) High serum immunoglobulin g and m levels predict freedom from adverse cardiovascular events in hypertension: a nested case-control substudy of the Anglo-Scandinavian cardiac outcomes trial. EBioMedicine, 9, pp. 372-380. (doi: 10.1016/j.ebiom.2016.06.012)

Feldman, T., Komtebedde, J., Burkhoff, D., Massaro, J., Maurer, M. S., Leon, M. B., Kaye, D., Silvestry, F. E., Cleland, J. G.F., Kitzman, D., Kubo, S. H., Van Veldhuisen, D. J., Kleber, F., Trochu, J.-N., Auricchio, A., Gustafsson, F., Hasenfuβ, G., Ponikowski, P., Filippatos, G., Mauri, L., Shah, S. J. (2016) Transcatheter interatrial shunt device for the treatment of heart failure: rationale and design of the randomized trial to REDUCE elevated left atrial pressure in heart failure (REDUCE LAP-HF I) Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003025)

Currie, G., Delles, C. (2016) Use of biomarkers in the evaluation and treatment of hypertensive patients. Current Hypertension Reports, 18, (doi: 10.1007/s11906-016-0661-6)

Wannamethee, S. G., Welsh, P., Lennon, L., Papacosta, O., Whincup, P., Sattar, N. (2016) Copeptin and risk of incident stroke, coronary heart disease and cardiovascular mortality in older men with and without diabetes: The British Regional Heart Study. Diabetologia, 59, pp. 1904-1912. (doi: 10.1007/s00125-016-4011-7)

Voors, A. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., ter Maaten, J. M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M. (2016) A systems BIOlogy Study to TAilored treatment in chronic heart failure: rationale, design, and baseline characteristics of BIOSTAT-CHF. European Journal of Heart Failure, 18, pp. 716-726. (doi: 10.1002/ejhf.531)

Welsh, P., Cezard, G., Gill, J.M., Wallia, S., Douglas, A., Sheikh, A., Wild, S.H., Tuomilehto, J., McKnight, J., Murray, G., Bhopal, R., Lean, M., Sattar, N. (2016) Associations between weight change and biomarkers of cardiometabolic risk in South Asians: secondary analyses of the PODOSA Trial. International Journal of Obesity, 40, pp. 1005-1011. (doi: 10.1038/ijo.2016.35)

ter Maaten, J. M., Valente, M. A.E., Damman, K., Cleland, J. G., Givertz, M. M., Metra, M., O’Connor, C. M., Teerlink, J. R., Ponikowski, P., Bloomfield, D. M., Cotter, G., Davison, B., Subacius, H., van Veldhuisen, D. J., van der Meer, P., Hillege, H. L., Gheorghiade, M., Voors, A. A. (2016) Combining diuretic response and hemoconcentration to predict rehospitalization after admission for acute heart failure. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.115.002845)

Wannamethee, G., Shaper, G., Papacosta, O., Lennon, L., Welsh, P., Whincup, P. (2016) Lung function and airway obstruction: associations with circulating markers of cardiac function and incident heart failure in older men—the British regional heart study. Thorax, 71, pp. 526-534. (doi: 10.1136/thoraxjnl-2014-206724)

Emmens, J. E., ter Maaten, J. M., Matsue, Y., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Todd, J., van Veldhuisen, D. J., Hillege, H. L., Damman, K., van der Meer, P., Voors, A. A. (2016) Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome. European Journal of Heart Failure, 18, pp. 641-649. (doi: 10.1002/ejhf.426)

Sharp, A. S. P. et al. (2016) Renal artery sympathetic denervation: observations from the UK experience. Clinical Research in Cardiology, 105, pp. 544-552. (doi: 10.1007/s00392-015-0959-4)

Pedersen, C. M., Venkatasubramanian, S., Vase, H., Hyldebrandt, J. A., Contractor, H., Schmidt, M. R., Bøtker, H. E., Cruden, N. L., Newby, D. E., Kharbanda, R. K., Lang, N. N. (2016) Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury. British Journal of Clinical Pharmacology, 81, pp. 1037-1045. (doi: 10.1111/bcp.12882)

Ballantyne, M. D., Pinel, K., Dakin, R., Vesey, A. T., Diver, L., MacKenzie, R., Garcia, R., Welsh, P., Sattar, N., Hamilton, G., Joshi, N., Dweck, M. R., Miano, J. M., McBride, M. W., Newby, D. E., McDonald, R. A., Baker, A. H. (2016) Smooth muscle enriched long noncoding RNA (SMILR) regulates cell proliferation. Circulation, 133, pp. 2050-2065. (doi: 10.1161/circulationaha.115.021019)

Carrick, D., Haig, C., Carberry, J., Teng Tue May, V., Mccartney, P., Welsh, P., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Mahrous, A., Rauhalammi, S. M.O., Mordi, I., Ford, I., Radjenovic, A., Sattar, N., Oldroyd, K. G., Berry, C. (2016) Microvascular resistance of the culprit coronary artery in acute ST-elevation myocardial infarction. JCI Insight, 1, (doi: 10.1172/jci.insight.85768)

Pellicori, P., Goode, K. M., Nicholls, R., Ahmed, D., Clark, A. L., Cleland, J. G.F. (2016) Regional circulatory distribution of novel cardiac bio-markers and their relationships with haemodynamic measurements. International Journal of Cardiology, 210, pp. 149-155. (doi: 10.1016/j.ijcard.2016.02.081)

Gheorghiade, M., Larson, C. J., Shah, S. J., Greene, S. J., Cleland, J. G.F., Colucci, W. S., Dunnmon, P., Epstein, S. E., Kim, R. J., Parsey, R. V., Stockbridge, N., Carr, J., Dinh, W., Krahn, T., Kramer, F., Wahlander, K., Deckelbaum, L. I., Crandall, D., Okada, S., Senni, M., Sikora, S., Sabbah, H. N., Butler, J. (2016) Developing new treatments for heart failure: focus on the heart. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.115.002727)

Venkatasubramanian, S., Noh, R. M., Daga, S., Langrish, J. P., Mills, N. L., Waterhouse, B. R., Hoffmann, E., Jacobson, E. W., Lang, N. N., Frier, B. M., Newby, D. E. (2016) Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus. Open Heart, 3, (doi: 10.1136/openhrt-2016-000402)

Shoaib, A., Farag, M., Nasir, M., John, J., Gupta, S., Pellicori, P., Antony, R., Perveen, R., Rigby, A., Goode, K. M., Yassin, A., Clark, A. L., Cleland, J. G.F. (2016) Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1. European Journal of Heart Failure, 18, pp. 556-563. (doi: 10.1002/ejhf.505)

Pellicori, P., Cleland, J.G.F. (2016) New ways to visualize and combat congestion in heart failure = Nuevos modos de visualizar y combatir la congestión en la insuficiencia cardiaca. Revista Clínica Española, 216, pp. 202-204. (doi: 10.1016/j.rce.2016.03.007)

Kotecha, D., Manzano, L., Krum, H., Rosano, G., Holmes, J., Altman, D. G., Collins, P. D., Packer, M., Wikstrand, J., Coats, A. J.S., Cleland, J. G.F., Kirchhof, P., von Lueder, T. G., Rigby, A. S., Andersson, B., Lip, G. Y.H., van Veldhuisen, D. J., Shibata, M. C., Wedel, H., Böhm, M., Flather, M. D. (2016) Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis. British Medical Journal, 353, (doi: 10.1136/bmj.i1855)

Wan Sulaiman, W.N., Caslake, M.J., Delles, C., Karlsson, H., Mulder, M.T., Graham, D., Freeman, D.J. (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130, pp. 491-497. (doi: 10.1042/cs20150475)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Lindsay, M., Mahrous, A., Ford, I., Tzemos, N., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Prognostic significance of infarct core pathology revealed by quantitative non-contrast in comparison to contrast cardiac magnetic resonance imaging in reperfused ST-elevation myocardial infarction survivors. European Heart Journal, 37, pp. 1044-1059. (doi: 10.1093/eurheartj/ehv372)

Eisele, N., Albrecht, C., Mistry, H. D., Dick, B., Baumann, M., Surbek, D., Currie, G., Delles, C., Mohaupt, M. G., Escher, G., Gennari-Moser, C. (2016) Placental expression of the angiogenic placental growth factor is stimulated by both aldosterone and simulated starvation. Placenta, 40, pp. 18-24. (doi: 10.1016/j.placenta.2016.02.004)

Ovchinnikova, E. S. et al. (2016) Signature of circulating microRNAs in patients with acute heart failure. European Journal of Heart Failure, 18, pp. 414-423. (doi: 10.1002/ejhf.332)

Koshy, A., Pellicori, P., Clark, A. L. (2016) The effect of increasing inspired oxygen on exercise performance in patients with chronic heart failure. Heart, 102, pp. 597-601. (doi: 10.1136/heartjnl-2015-308932)

Neisius, U., Koeck, T., Mischak, H., Rossi, S. H., Olson, E., Carty, D. M., Dymott, J. A., Dominiczak, A. F., Berry, C., Oldroyd, K. G., Delles, C. (2016) Urine proteomics in the diagnosis of stable angina. BMC Cardiovascular Disorders, 16, (doi: 10.1186/s12872-016-0246-y)

Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Ponikowski, P., Metra, M., Filippatos, G. S., Ezekowitz, J. A., Dickstein, K., Cleland, J. G.F., Kim, J. B., Lei, L., Knusel, B., Wolff, A. A., Malik, F. I., Wasserman, S. M. (2016) Acute treatment with omecamtiv mecarbil to increase contractility in acute heart failure. Journal of the American College of Cardiology, 67, pp. 1444-1455. (doi: 10.1016/j.jacc.2016.01.031)

Hasenfuß, G., Hayward, C., Burkhoff, D., Silvestry, F. E., McKenzie, S., Gustafsson, F., Malek, F., Van der Heyden, J., Lang, I., Petrie, M. C., Cleland, J. G.F., Leon, M., Kaye, D. M. (2016) A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial. Lancet, 387, pp. 1298-1304. (doi: 10.1016/S0140-6736(16)00704-2)

Durussel, J., Haile, D., Mooses, K., Daskalaki, E., Beattie, W., Mooses, M., Mekonen, W., Ongaro, N., Anjila, E., Patel, R., Padmanabhan, N., McBride, M., McClure, J., Pitsiladis, Y. (2016) Blood transcriptional signature of recombinant human erythropoietin administration and implications for antidoping strategies. Physiological Genomics, 48, pp. 202-209. (doi: 10.1152/physiolgenomics.00108.2015)

Loomis, A. K., Kabadi, S., Preiss, D., Hyde, C., Bonato, V., St. Louis, M., Desai, J., Gill, J. M.R., Welsh, P., Waterworth, D., Sattar, N. (2016) Body mass index and risk of non-alcoholic fatty liver disease: two electronic health record prospective studies. Journal of Clinical Endocrinology and Metabolism, 101, pp. 945-952. (doi: 10.1210/jc.2015-3444)

Mullan, A., Delles, C., Ferrell, W., Mullen, W., Edwards, C. A., McColl, J. H., Roberts, S. A., Lean, M. (2016) Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized trial. Atherosclerosis, 246, pp. 169-176. (doi: 10.1016/j.atherosclerosis.2016.01.004)

Damman, K., Kjekshus, J., Wikstrand, J., Cleland, J. G.F., Komajda, M., Wedel, H., Waagstein, F., McMurray, J. J.V. (2016) Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction. European Journal of Heart Failure, 18, pp. 328-336. (doi: 10.1002/ejhf.462)

Demissei, B. G., Valente, M. A.E., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van der Meer, P., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A. (2016) Optimizing clinical use of biomarkers in high-risk acute heart failure patients. European Journal of Heart Failure, 18, pp. 269-280. (doi: 10.1002/ejhf.443)

Cuba Gyllensten, I., Bonomi, A. G., Goode, K. M., Reiter, H., Habetha, J., Amft, O., Cleland, J. G.F. (2016) Early indication of decompensated heart failure in patients on home-telemonitoring: a comparison of prediction algorithms based on daily weight and noninvasive transthoracic bio-impedance. JMIR Medical Informatics, 4, (doi: 10.2196/medinform.4842)

Demissei, B. G., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Davison, B., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., Cotter, G. (2016) Procalcitonin-based indication of bacterial infection identifies high risk acute heart failure patients. International Journal of Cardiology, 204, pp. 164-171. (doi: 10.1016/j.ijcard.2015.11.141)

ter Maaten, J. M., Valente, M. A.E., Metra, M., Bruno, N., O’Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., van Veldhuisen, D. J., Hillege, H. L., Damman, K., Voors, A. A. (2016) A combined clinical and biomarker approach to predict diuretic response in acute heart failure. Clinical Research in Cardiology, 105, pp. 145-153. (doi: 10.1007/s00392-015-0896-2)

Currie, G., Delles, C., Touyz, R. M., Staessen, J. A., Dominiczak, A. F., Jennings, G. L. R., Wang, J.-G. (2016) A woman with treatment-resistant hypertension. Hypertension, 67, pp. 243-250. (doi: 10.1161/HYPERTENSIONAHA.115.06756)

Jones, F. E., Bailey, M. A., Murray, L. S., Lu, Y., McNeilly, S., Schlötzer-Schrehardt, U., Lennon, R., Sado, Y., Brownstein, D. G., Mullins, J. J., Kadler, K. E., Van Agtmael, T. (2016) ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice. Disease Models and Mechanisms, 9, pp. 165-76. (doi: 10.1242/dmm.021741)

Bhandari, S., Ives, N., Brettell, E. A., Valente, M., Cockwell, P., Topham, P. S., Cleland, J. G.F., Khwaja, A., El Nahas, M. (2016) Multicentre randomized controlled trial of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker withdrawal in advanced renal disease: the STOP-ACEi trial. Nephrology Dialysis Transplantation, 31, pp. 255-261. (doi: 10.1093/ndt/gfv346)

Welsh, P., Hart, C., Papacosta, O., Preiss, D., McConnachie, A., Murray, H., Ramsay, S., Upton, M., Watt, G., Whincup, P., Wannamethee, G., Sattar, N. (2016) Prediction of cardiovascular disease risk by cardiac biomarkers in 2 United Kingdom cohort studies: does utility depend on risk thresholds for treatment? Hypertension, 2016, pp. 309-315. (doi: 10.1161/HYPERTENSIONAHA.115.06501)

Small, H. Y., Currie, G. E., Delles, C. (2016) Prostasin, proteases, and preeclampsia. Journal of Hypertension, 34, pp. 193-195. (doi: 10.1097/hjh.0000000000000828)

Carrick, D., Haig, C., Rauhalammi, S., Clerfond, G., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Mahrous, A., Welsh, P., Sattar, N., Ford, I., Oldroyd, K., Radjenovic, A., Berry, C. (2016) Temporal evolution of myocardial hemorrhage and edema in patients after acute ST-elevation myocardial infarction: pathophysiologic insights and clinical implications. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.115.002834)

Bruno, N., ter Maaten, J. M., Ovchinnikova, E. S., Vegter, E. L., Valente, M. A.E., van der Meer, P., de Boer, R. A., van der Harst, P., Schmitter, D., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Pinto, Y. M., van Veldhuisen, D. J., Hillege, H. L., Berezikov, E., Voors, A. A. (2016) MicroRNAs relate to early worsening of renal function in patients with acute heart failure. International Journal of Cardiology, 203, pp. 564-569. (doi: 10.1016/j.ijcard.2015.10.217)

Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., Cleland, J. G.F. (2016) Exploring quality of life in patients with and without heart failure. International Journal of Cardiology, 202, pp. 676-684. (doi: 10.1016/j.ijcard.2015.09.076)

Small, H. Y., Morgan, H., Beattie, E., Griffin, S., Indahl, M., Delles, C., Graham, D. (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022)

Cowie, M. R., Bax, J., Bruining, N., Cleland, J. G.F., Koehler, F., Malik, M., Pinto, F., van der Velde, E., Vardas, P. (2016) e-Health: a position statement of the European Society of Cardiology. European Heart Journal, 37, pp. 63-66. (doi: 10.1093/eurheartj/ehv416)

Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G.F., Coats, A. J.S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., Jessup, M., Linde, C., Nihoyannopoulos, P., Parissis, J. T., Pieske, B., Riley, J. P., Rosano, G. M.C., Ruilope, L. M., Ruschitzka, F., Rutten, F. H., van der Meer, P., McMurray, J. J.V., Petrie, M. C. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 37, pp. 2129-2200. (doi: 10.1093/eurheartj/ehw128)

Olsen, M. H., Angell, S. Y., Asma, S., Boutouyrie, P., Burger, D., Chirinos, J. A., Damasceno, A., Delles, C., Gimenez-Roqueplo, A.-P., Hering, D., López-Jaramillo, P., Martinez, F., Perkovic, V., Rietzschel, E. R., Schillaci, G., Schutte, A. E., Scuteri, A., Sharman, J. E., Wachtell, K., Wang, J. G. (2016) A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension. Lancet, 388, pp. 2665-2712. (doi: 10.1016/S0140-6736(16)31134-5)

Colman, M. A., Sarathy, P. P., MacQuiaide, N., Workman, A. J. (2016) A new model of the human atrial myocyte with variable T-tubule organization for the study of atrial fibrillation. Computing in Cardiology, 43, pp. 221-224. (doi: 10.23919/CIC.2016.7868719)

Boulberdaa, M., Scott, E., Ballantyne, M., Garcia, R., Descamps, B., Angelini, G. D., Brittan, M., Hunter, A., McBride, M., McClure, J., Miano, J. M., Emanueli, C., Mills, N. L., Mountford, J. C., Baker, A. H. (2016) A role for the long non-coding RNA SENCR in commitment and function of endothelial cells. Molecular Therapy, 24, pp. 978-990. (doi: 10.1038/mt.2016.41)

Rankin, N. J., Preiss, D., Welsh, P., Sattar, N. (2016) Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future. International Journal of Epidemiology, 45, pp. 1351-1371. (doi: 10.1093/ije/dyw271)

Zhang, Z.-y., Ravassa, S., Yang, W.-Y., Petit, T., Pejchinovski, M., Zürbig, P., López, B., Wei, F.-F., Pontillo, C., Thijs, L., Jacobs, L., González, A., Koeck, T., Delles, C., Voigt, J.-U., Verhamme, P., Kuznetsova, T., Díez, J., Mischak, H., Staessen, J. A. (2016) Diastolic left ventricular function in relation to urinary and serum collagen biomarkers in a general population. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167582)

McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C., Milligan, G., Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52, pp. 383-395. (doi: 10.1159/000444754)

Carrick, D., Haig, C., Watkins, S., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Davie, A., Mahrous, A., Mordi, I., Rauhalammi, S., Sattar, N., Welsh, P., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/CIRCIMAGING.115.004148)

Gillis, K. A., Mccomb, C., Patel, R. K., Stevens, K. K., Schneider, M. P., Radjenovic, A., Morris, S. T.W., Roditi, G. H., Delles, C., Mark, P. B. (2016) Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease. Nephron, 133, pp. 183-192. (doi: 10.1159/000447601)

Stoumpos, S., McNeill, S. H., Gorrie, M., Mark, P. B., Brennand, J. E., Geddes, C. C., Deighan, C. J. (2016) Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study. Clinical Transplantation, 30, pp. 673-681. (doi: 10.1111/ctr.12732)

Lindhardt, M., Persson, F., Currie, G., Pontillo, C., Beige, J., Delles, C., von der Leyen, H., Mischak, H., Navis, G., Noutsou, M., Ortiz, A., Ruggenenti, P. L., Rychlik, I., Spasovski, G., Rossing, P. (2016) Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial. BMJ Open, 6, (doi: 10.1136/bmjopen-2015-010310)

Sheikh, A. M., Small, H. Y., Currie, G., Delles, C. (2016) Systematic review of micro-RNA expression in pre-eclampsia identifies a number of common pathways associated with the disease. PLoS ONE, 11, (doi: 10.1371/journal.pone.0160808)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., Anker, S. D., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J. V. (2016) The incremental prognostic and clinical value of multiple novel biomarkers in heart failure. European Journal of Heart Failure, 18, pp. 1491-1498. (doi: 10.1002/ejhf.543)

Emdin, C. A., Conrad, N., Kiran, A., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., Dargie, H. J., Hardman, S. M.C., McDonagh, T., McMurray, J. J.V., Cleland, J. G.F., Rahimi, K. (2016) Variation in hospital performance for heart failure management in the National Heart Failure Audit for England and Wales. Heart, 103, pp. 55-62. (doi: 10.1136/heartjnl-2016-309706)

Rutherford, E., Mark, P. (2016) What does STOP-IgAN tell us about how to treat IgA nephropathy? Journal of the Royal College of Physicians of Edinburgh, 46, pp. 23-25. (doi: 10.4997/JRCPE.2016.107)

2015

Cameron, A. C., Touyz, R. M., Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32, pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023)

Cleland, J. G.F., Mareev, Y. (2015) CRT for heart failure and ESRD: more trials or more thought needed? Journal of the American College of Cardiology, 66, pp. 2630-2632. (doi: 10.1016/j.jacc.2015.10.022)

Solbu, M. D., Thomson, P. C., Macpherson, S., Findlay, M. D., Stevens, K. K., Patel, R. K., Padmanabhan, S., Jardine, A. G., Mark, P. B. (2015) Serum phosphate and social deprivation independently predict all-cause mortality in chronic kidney disease. BMC Nephrology, 16, (doi: 10.1186/s12882-015-0187-1)

Jolicœur, E. M., Dunning, A., Castelvecchio, S., Dabrowski, R., Waclawiw, M. A., Petrie, M. C., Stewart, R., Jhund, P. S., Desvigne-Nickens, P., Panza, J. A., Bonow, R. O., Sun, B., San, T. R., Al-Khalidi, H. R., Rouleau, J. L., Velazquez, E. J., Cleland, J. G.F. (2015) Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction. Journal of the American College of Cardiology, 66, pp. 2092-2100. (doi: 10.1016/j.jacc.2015.08.882)

Pellicori, P., Joseph, A. C., Zhang, J., Lukaschuk, E., Sherwi, N., Bourantas, C. V., Loh, H., Clark, A. L., Cleland, J. G.F. (2015) The relationship of QRS morphology with cardiac structure and function in patients with heart failure. Clinical Research in Cardiology, 104, pp. 935-945. (doi: 10.1007/s00392-015-0861-0)

Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2015) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Cochrane Database of Systematic Reviews, 2015, (doi: 10.1002/14651858.CD007228.pub3)

Deng, L., Blanco Lopez, F. J., Stevens, H., Lu, R., Caudrillier, A., McBride, M., McClure, J. D., Grant, J., Thomas, M., Frid, M., Stenmark, K., White, K., Seto, A. G., Morrell, N. W., Bradshaw, A. C., MacLean, M. R., Baker, A. H. (2015) MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circulation Research, 117, pp. 870-883. (doi: 10.1161/CIRCRESAHA.115.306806)

Farag, M., Mabote, T., Shoaib, A., Zhang, J., Nabhan, A. F., Clark, A. L., Cleland, J. G. (2015) Hydralazine and nitrates alone or combined for the management of chronic heart failure: a systematic review. International Journal of Cardiology, 196, pp. 61-69. (doi: 10.1016/j.ijcard.2015.05.160)

Mareev, Y., Cleland, J. G.F. (2015) Should β-blockers be used in patients with heart failure and atrial fibrillation? Clinical Therapeutics, 37, pp. 2215-2224. (doi: 10.1016/j.clinthera.2015.08.017)

Shadman, R., Poole, J. E., Dardas, T. F., Mozaffarian, D., Cleland, J. G.F., Swedberg, K., Maggioni, A. P., Anand, I. S., Carson, P. E., Miller, A. B., Levy, W. C. (2015) A novel method to predict the proportional risk of sudden cardiac death in heart failure: derivation of the Seattle Proportional Risk Model. Heart Rhythm, 12, pp. 2069-2077. (doi: 10.1016/j.hrthm.2015.06.039)

Patel, R., Jeemon, P., Stevens, K., Mccallum, L., Hastie, C., Schneider, A., Jardine, A., Mark, P., Padmanabhan, S. (2015) Association between serum phosphate and calcium, long-term blood pressure, and mortality in treated hypertensive adults. Journal of Hypertension, 33, pp. 2046-2053. (doi: 10.1097/hjh.0000000000000659)

Butcher, C., Mareev, Y., Markides, V., Mason, M., Wong, T., Cleland, J.G.F. (2015) Cardiac resynchronization therapy update: evolving indications, expanding benefit? Current Cardiology Reports, 17, (doi: 10.1007/s11886-015-0641-5)

Akehurst, C., Small, H., Sharafetdinova, L., Forrest, R., Beattie, W., Brown, C. E., Robinson, S. W., McClure, J. D., Work, L. M., Carty, D. M., McBride, M. W., Freeman, D. J., Delles, C. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33, pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656)

Frankenstein, L., Fröhlich, H., Cleland, J. G.F. (2015) Multidisciplinary approach for patients hospitalized with heart failure. Revista Española de Cardiología (English Edition), 68, pp. 885-891. (doi: 10.1016/j.rec.2015.05.008)

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892)

Cleland, J. G.F., Freemantle, N. (2015) QRS morphology as a predictor of the response to cardiac resynchronisation therapy: fact or fashion? Heart, 101, pp. 1441-1443. (doi: 10.1136/heartjnl-2015-307553)

Wannamethee, S. G., Welsh, P., Papacosta, O., Lennon, L., Whincup, P. H., Sattar, N. (2015) Copeptin, insulin resistance, and risk of incident diabetes in older men. Journal of Clinical Endocrinology and Metabolism, 100, pp. 3332-3339. (doi: 10.1210/JC.2015-2362)

Lindsey, M. L., Mayr, M., Gomes, A. V., Delles, C., Arrell, D. K., Murphy, A. M., Lange, R. A., Costello, C. E., Jin, Y.-F., Laskowitz, D. T., Sam, F., Terzic, A., Van Eyk, J., Srinivas, P. R. (2015) Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association. Circulation, 132, pp. 852-872. (doi: 10.1161/CIR.0000000000000226)

Pellicori, P., Clark, A. L. (2015) Clinical trials update from the European Society of Cardiology-Heart Failure meeting 2015: AUGMENT-HF, TITRATION, STOP-HF, HARMONIZE, LION HEART, MOOD-HF, and renin-angiotensin inhibitors in patients with heart and renal failure. European Journal of Heart Failure, 17, pp. 979-983. (doi: 10.1002/ejhf.340)

Damy, T., Hobkirk, J., Walters, M., Ciobanu, A., Rigby, A. S., Kallvikbacka-Bennett, A., Guellich, A., Dubois-Randé, J.-L., Hittinger, L., Clark, A. L., Cleland, J. G.F. (2015) Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure. Journal of Cardiovascular Pharmacology, 66, pp. 229-238. (doi: 10.1097/FJC.0000000000000262)

Dierckx, R., Cleland, J. G.F., Pellicori, P., Zhang, J., Goode, K., Putzu, P., Boyalla, V., Clark, A. L. (2015) If home telemonitoring reduces mortality in heart failure, is this just due to better guideline-based treatment? Journal of Telemedicine and Telecare, 21, pp. 331-339. (doi: 10.1177/1357633X15574947)

Findlay, M. D., Thomson, P. C., Fulton, R. L., Solbu, M. D., Jardine, A. G., Patel, R. K., Stevens, K. K., Geddes, C. C., Dawson, J., Mark, P. B. (2015) Risk factors of ischemic stroke and subsequent outcome in hemodialysis patients. Stroke, 46, pp. 2477-2481. (doi: 10.1161/STROKEAHA.115.009095)

Stut, W., Deighan, C., Cleland, J. G., Jaarsma, T. (2015) Adherence to self-care in patients with heart failure in the HeartCycle study. Patient Preference and Adherence, 9, pp. 1195-1206. (doi: 10.2147/PPA.S88482)

Lees, J. S., Mark, P. B., Jardine, A. G. (2015) Cardiovascular complications of chronic kidney disease. Medicine, 43, pp. 469-473. (doi: 10.1016/j.mpmed.2015.05.009)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., McInnes, I. B., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J.V. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3, pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014)

Schanstra, J.P. et al. (2015) Diagnosis and prediction of CKD progression by assessment of urinary peptides. Journal of the American Society of Nephrology, 26, pp. 1999-2010. (doi: 10.1681/asn.2014050423)

Mann, J. F.E., Rossing, P., Wiȩcek, A., Rosivall, L., Mark, P., Mayer, G. (2015) Diagnosis and treatment of early renal disease in patients with type 2 diabetes mellitus: what are the clinical needs? Nephrology Dialysis Transplantation, 30, pp. iv1-iv5. (doi: 10.1093/ndt/gfv120)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544)

Cleland, J. G.F., Mareev, Y., Linde, C. (2015) Reflections on EchoCRT: sound guidance on QRS duration and morphology for CRT? European Heart Journal, 36, pp. 1948-1951. (doi: 10.1093/eurheartj/ehv264)

Askevold, E. T., Gullestad, L., Nymo, S., Kjekshus, J., Yndestad, A., Latini, R., Cleland, J. G.F., McMurray, J. J.V., Aukrust, P., Ueland, T. (2015) Secreted frizzled related protein 3 in chronic heart failure: analysis from the controlled rosuvastatin multinational trial in heart failure (CORONA) PLoS ONE, 10, (doi: 10.1371/journal.pone.0133970)

Raphael, C. E., Finegold, J. A., Barron, A. J., Whinnett, Z. I., Mayet, J., Linde, C., Cleland, J. G.F., Levy, W. C., Francis, D. P. (2015) The effect of duration of follow-up and presence of competing risk on lifespan-gain from implantable cardioverter defibrillator therapy: who benefits the most? European Heart Journal, 36, pp. 1676-1688. (doi: 10.1093/eurheartj/ehv102)

Mentz, R. J., Metra, M., Cotter, G., Milo, O., McKendry, C., Chiswell, K., Davison, B. A., Cleland, J. G.F., Bloomfield, D. M., Dittrich, H. C., Fiuzat, M., Ponikowski, P., Givertz, M. M., Voors, A. A., Teerlink, J. R., O'Connor, C. M. (2015) Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 697-706. (doi: 10.1002/ejhf.308)

Ferrari, R., Böhm, M., Cleland, J. G.F., Paulus, W. J.S., Pieske, B., Rapezzi, C., Tavazzi, L. (2015) Heart failure with preserved ejection fraction: uncertainties and dilemmas. European Journal of Heart Failure, 17, pp. 665-671. (doi: 10.1002/ejhf.304)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Lindsay, M., Watkins, S., Hood, S., Davie, A., Marous, A., Sattar, N., Welsh, P., Tzemos, N., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2015) Pathophysiology of LV remodeling in survivors of STEMI : inflammation, remote myocardium, and prognosis. JACC: Cardiovascular Imaging, 8, pp. 779-789. (doi: 10.1016/j.jcmg.2015.03.007)

Pellicori, P., Kallvikbacka-Bennett, A., Dierckx, R., Zhang, J., Putzu, P., Cuthbert, J., Boyalla, V., Shoaib, A., Clark, A. L., Cleland, J. G.F. (2015) Prognostic significance of ultrasound-assessed jugular vein distensibility in heart failure. Heart, 101, pp. 1149-1158. (doi: 10.1136/heartjnl-2015-307558)

Zannad, F., Greenberg, B., Cleland, J. G.F., Gheorghiade, M., van Veldhuisen, D. J., Mehra, M. R., Anker, S. D., Byra, W. M., Fu, M., Mills, R. M. (2015) Rationale and design of a randomized, double-blind, event-driven, multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with heart failure and significant coronary artery disease following an exacerbation of heart failure: the COMMANDER HF trial. European Journal of Heart Failure, 17, pp. 735-742. (doi: 10.1002/ejhf.266)

McDonald, R. A., Halliday, C. A., Miller, A. M., Diver, L. A., Dakin, R. S., Montgomery, J., McBride, M. W., Kennedy, S., McClure, J. D., Robertson, K. E., Douglas, G., Channon, K. M., Oldroyd, K., Baker, A. H. (2015) Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation. Journal of the American College of Cardiology, 65, pp. 2314-2327. (doi: 10.1016/j.jacc.2015.03.549)

Inglis, S. C., Conway, A., Cleland, J. G.F., Clark, R. A. (2015) Is age a factor in the success or failure of remote monitoring in heart failure? Telemonitoring and structured telephone support in elderly heart failure patients. European Journal of Cardiovascular Nursing, 14, pp. 248-255. (doi: 10.1177/1474515114530611)

Kristensen, S. L., Jhund, P. S., Køber, L., McKelvie, R. S., Zile, M. R., Anand, I. S., Komajda, M., Cleland, J. G.F., Carson, P. E., McMurray, J. J.V. (2015) Relative importance of history of heart failure hospitalization and N-terminal pro–B-type natriuretic peptide level as predictors of outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 3, pp. 478-486. (doi: 10.1016/j.jchf.2015.01.014)

Dakin, R. S., Parker, A. L., Delles, C., Nicklin, S. A., Baker, A. H. (2015) Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector. Human Gene Therapy, 26, pp. 312-319. (doi: 10.1089/hum.2015.019)

Fox, C. S., Hall, J. L., Arnett, D. K., Ashley, E. A., Delles, C., Engler, M. B., Freeman, M. W., Johnson, J. A., Lanfear, D. E., Liggett, S. B., Lusis, A. J., Loscalzo, J., MacRae, C. A., Musunuru, K., Newby, L. K., O'Donnell, C. J., Rich, S. S., Terzic, A. (2015) Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation, 131, pp. 1715-1736. (doi: 10.1161/CIR.0000000000000211)

Costanzo, P., Cleland, J. G.F., Pellicori, P., Clark, A. L., Hepburn, D., Kilpatrick, E. S., Perrone-Filardi, P., Zhang, J., Atkin, S. L. (2015) The obesity paradox in type 2 diabetes mellitus: relationship of body mass index to prognosis: a cohort study. Annals of Internal Medicine, 162, pp. 610-618. (doi: 10.7326/M14-1551)

Rutherford, M.A., Rankin, A.J., Yates, T.M., Mark, P.B., Perry, C.G., Reed, N.S., Freel, E.M. (2015) Management of metastatic phaeochromocytoma and paraganglioma: use of Iodine-131-meta-iodobenzylguanidine (131I-MIBG) therapy in a tertiary referral centre. QJM: An International Journal of Medicine, 108, pp. 361-368. (doi: 10.1093/qjmed/hcu208)

Filippatos, G., Khan, S. S., Ambrosy, A. P., Cleland, J. G.F., Collins, S. P., Lam, C. S.P., Angermann, C. E., Ertl, G., Dahlström, U., Hu, D., Dickstein, K., Perrone, S. V., Ghadanfar, M., Bermann, G., Noe, A., Schweizer, A., Maier, T., Gheorghiade, M. (2015) International REgistry to assess medical practice with lOngitudinal obseRvation for Treatment of Heart Failure (REPORT-HF): rationale for and design of a global registry. European Journal of Heart Failure, 17, pp. 527-533. (doi: 10.1002/ejhf.262)

Davison, B. A., Metra, M., Cotter, G., Massie, B. M., Cleland, J. G.F., Dittrich, H. C., Edwards, C., Filippatos, G., Givertz, M. M., Greenberg, B., Ponikowski, P., Voors, A. A., O’Connor, C. M., Teerlink, J. R. (2015) Worsening heart failure following admission for acute heart failure: a pooled analysis of the PROTECT and RELAX-AHF studies. JACC: Heart Failure, 3, pp. 395-403. (doi: 10.1016/j.jchf.2015.01.007)

Ravassa, S., Kuznetsova, T., Varo, N., Thijs, L., Delles, C., Dominiczak, A., Díez, J., Staessen, J. A. (2015) Biomarkers of cardiomyocyte injury and stress identify left atrial and left ventricular remodelling and dysfunction: a population-based study. International Journal of Cardiology, 185, pp. 177-185. (doi: 10.1016/j.ijcard.2015.03.046)

Rousset, C. I., Leiper, F. C., Kichev, A., Gressens, P., Carling, D., Hagberg, H., Thornton, C. (2015) A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice. Journal of Neurochemistry, 133, pp. 242-252. (doi: 10.1111/jnc.13034)

McInnes, I. B., Thompson, L., Giles, J. T., Bathon, J. M., Salmon, J. E., Beaulieu, A. D., Codding, C. E., Carlson, T. H., Delles, C., Lee, J. S., Sattar, N. (2015) Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study. Annals of the Rheumatic Diseases, 74, pp. 694-702. (doi: 10.1136/annrheumdis-2013-204345)

Mischak, H., Delles, C., Vlahou, A., Vanholder, R. (2015) Proteomic biomarkers in kidney disease: issues in development and implementation. Nature Reviews Nephrology, 11, pp. 221-232. (doi: 10.1038/nrneph.2014.247)

Cleland, J. G.F., Butcher, C. (2015) When is it appropriate to withdraw cardiac resynchronization therapy? Guesses and evidence. JACC: Heart Failure, 3, pp. 337-339. (doi: 10.1016/j.jchf.2015.01.003)

Pellicori, P., Zhang, J., Lukaschuk, E., Joseph, A. C., Bourantas, C. V., Loh, H., Bragadeesh, T., Clark, A. L., Cleland, J. G.F. (2015) Left atrial function measured by cardiac magnetic resonance imaging in patients with heart failure: clinical associations and prognostic value. European Heart Journal, 36, pp. 733-742. (doi: 10.1093/eurheartj/ehu405)

Rannikmäe, K. et al. (2015) Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease. Neurology, 84, pp. 918-926. (doi: 10.1212/WNL.0000000000001309)

Jankowska, E. A., Wojtas, K., Kasztura, M., Mazur, G., Butrym, A., Kalicinska, E., Rybinska, I., Skiba, J., von Haehling, S., Doehner, W., Anker, S. D., Banasiak, W., Cleland, J. G.F., Ponikowski, P. (2015) Bone marrow iron depletion is common in patients with coronary artery disease. International Journal of Cardiology, 182, pp. 517-522. (doi: 10.1016/j.ijcard.2014.10.006)

Metra, M., Cotter, G., El-Khorazaty, J., Davison, B. A., Milo, O., Carubelli, V., Bourge, R. C., Cleland, J. G., Jondeau, G., Krum, H., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Rainisio, M., Kobrin, I., McMurray, J. J., Teerlink, J. R. (2015) Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study. Journal of Cardiac Failure, 21, pp. 179-88. (doi: 10.1016/j.cardfail.2014.12.012)

Skogstrand, T., Leh, S., McClure, J., Dashti, M., Iversen, B. M., Graham, D., McBride, M., Hultström, M. (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33, pp. 584-596. (doi: 10.1097/HJH.0000000000000395)

Pellicori, P., Cleland, J. G.F. (2015) Is the epidemic of heart disease really over or just evolving? American Journal of Medicine, 128, pp. e17. (doi: 10.1016/j.amjmed.2014.09.018)

Dierckx, R., Cleland, J. G.F., Parsons, S., Putzu, P., Pellicori, P., Dicken, B., Boyalla, V., Clark, A. L. (2015) Prescribing patterns to optimize heart rate: analysis of 1,000 consecutive outpatient appointments to a single heart failure clinic over a 6-month period. JACC: Heart Failure, 3, pp. 224-230. (doi: 10.1016/j.jchf.2014.11.003)

Khand, A. U., Chew, P. G., Douglas, H., Jones, J., Jan, A., Cleland, J.G.F. (2015) The effect of carvedilol on b-type natriuretic peptide and cardiac function in patients with heart failure and persistent atrial fibrillation. Cardiology, 130, pp. 153-158. (doi: 10.1159/000368746)

Pellicori, P., Cleland, J. G.F. (2015) Update on management of heart failure with preserved ejection fraction. Current Opinion in Cardiology, 30, pp. 173-178. (doi: 10.1097/HCO.0000000000000152)

Kristensen, S. L., Jhund, P. S., Køber, L., Preiss, D., Kjekshus, J., McKelvie, R. S., Zile, M. R., Anand, I. S., Wikstrand, J. G.F., Wedel, H., Komajda, M., Carson, P. E., Cleland, J., McMurray, J. J.V. (2015) Comparison of outcomes after hospitalization for worsening heart failure, myocardial infarction, and stroke in patients with heart failure and reduced and preserved ejection fraction. European Journal of Heart Failure, 17, pp. 169-176. (doi: 10.1002/ejhf.211)

Boyalla, V., Putzu, P., Dierckx, R., Clark, A. L., Pellicori, P. (2015) Patent Ductus Arteriosus in older adults: incidental finding or relevant pathology? Journal of the American Geriatrics Society, 63, pp. 409-411. (doi: 10.1111/jgs.13256)

Alday, E. A. P., Colman, M. A., Langley, P., Butters, T. D., Higham, J., Workman, A. J., Hancox, J. C., Zhang, H. (2015) A new algorithm to diagnose atrial ectopic origin from multi lead ECG systems: insights from 3D virtual human atria and torso. PLoS Computational Biology, 11, pp. e1004026. (doi: 10.1371/journal.pcbi.1004026)

Metra, M., Mentz, R. J., Chiswell, K., Bloomfield, D. M., Cleland, J. G.F., Cotter, G., Davison, B. A., Dittrich, H. C., Fiuzat, M., Givertz, M. M., Lazzarini, V., Mansoor, G. A., Massie, B. M., Ponikowski, P., Teerlink, J. R., Voors, A. A., O'Connor, C. M. (2015) Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial. European Journal of Heart Failure, 17, pp. 109-118. (doi: 10.1002/ejhf.207)

Stoumpos, S., Jardine, A. G., Mark, P. B. (2015) Cardiovascular morbidity and mortality after kidney transplantation. Transplant International, 28, pp. 10-21. (doi: 10.1111/tri.12413)

Dickstein, K., Normand, C., Anker, S.D., Auricchio, A., Lundqvist Blomstrom, C., Bogale, N., Cleland, J., Filippatos, G., Gasparini, M., Gitt, A., Hindricks, G., Kuck, K.-H., Ponikowski, P., Stellbrink, C., Ruschitzka, F., Linde, C. (2015) European cardiac resynchronization therapy survey II: rationale and design. Europace, 17, pp. 137-141. (doi: 10.1093/europace/euu312)

McArthur, L., Johnston, L., Sattar, N., Logue, J., Welsh, P. (2015) Preanalytical study of fetuin-A: effect of sample type, processing speed and freeze-thaw cycles. Annals of Clinical Biochemistry, 52, pp. 165-168. (doi: 10.1177/0004563214529550)

Dierckx, R., Pellicori, P., Cleland, J.G.F., Clark, A.L. (2015) Telemonitoring in heart failure: Big Brother watching over you. Heart Failure Reviews, 20, pp. 107-116. (doi: 10.1007/s10741-014-9449-4)

Musunuru, K., Hickey, K. T., Al-Khatib, S. M., Delles, C., Fornage, M., Fox, C. S., Frazier, L., Gelb, B. D., Herrington, D. M., Lanfear, D. E., Rosand, J. (2015) Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. Circulation: Cardiovascular Genetics, 8, pp. 216-242. (doi: 10.1161/HCG.0000000000000020)

Pellicori, P., Costanzo, P. (2015) Betabloccanti in pazienti con scompenso cardiaco e fibrillazione atriale = [Betablockers in patients with heart failure and atrial fibrillation] Giornale italiano di cardiologia, 16, pp. 613-616. (doi: 10.1714/2066.22428)

Welsh, P., Preiss, D., Touyz, R. M. (2015) Biomarkers of hypertension and cardiovascular disease. Royal Society of Chemistry

Welsh, P., Preiss, D., Tsiropoulou, S., Rios, F. J., Harvey, A., Dulak-Lis, M. G., Montezano, A. C., Touyz, R. M. (2015) Biomarkers of vascular inflammation and cardiovascular disease. Springer

Pellicori, P., Kaur, K., Clark, A. L. (2015) Fluid management in patients with chronic heart failure. Cardiac Failure Review, 1, pp. 90-95. (doi: 10.15420/cfr.2015.1.2.90)

Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S., Porteous, D. J., Starr, J., Deary, I. J., Wardlaw, J. M. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46, pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649)

Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C., Currie, G., Schlembach, D., Mohaupt, M.G., Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, (doi: 10.1186/s12958-015-0100-6)

Sattar, N., Welsh, P., Preiss, D. (2015) The insulin resistance syndrome. John Wiley & Sons, Ltd

Brown, C. E., McCarthy, N. S., Hughes, A. D.,, Sever, P., Stalmach, A., Mullen, W., Dominiczak, A. F., Sattar, N., Mischak, H., Thom, S., Mayet, J., Stanton, A. V., Delles, C. (2015) Urinary proteomic biomarkers to predict cardiovascular events. Proteomics Clinical Applications, 9, pp. 610-617. (doi: 10.1002/prca.201400195)

PGR Students

Qiaoling Liu 

  • Postgraduate Research Student 
  • Research title: Physical Activity and Its Association with CVD

The kidney theme is led by clinical academic nephrologists (kidney specialists) working in tandem with NHS colleagues working at the Glasgow Renal and Transplant Unit at the Queen Elizabeth University Hospital, Glasgow as well as wider collaborations with academics across the MVLS college.

Chronic kidney disease leads to premature death, and we focus on better understanding and treating the leading causes of death of people with kidney disease, namely cardiovascular disease and cancer. To achieve these aims.

  • We use epidemiological (‘big data’) research to understand why people with kidney disease are at higher risk of these conditions and address what can be done to reduce this risk.
  • We undertake clinical trials to assess what are the best treatments to improve survival and reduce the risk of cardiovascular disease for people with kidney disease.
  • We work closely with our Kidney Patient and Public Involvement and Engagement group to guide our research aims and to improve dissemination and impact.
  • We collaborate widely with researchers at the University of Glasgow, across the United Kingdom, and internationally, working with academics, NHS clinicians and the pharmaceutical industry.

The impacts of our work will improve the health of people with or at risk of kidney disease.