Stroke

Cerebrovascular diseases including stroke are leading causes of disability, cognitive impairment, and death. Our research covers all facets of cerebrovascular disease, from understanding molecular mechanisms to developing new therapies. 

Staff

Publications

2024

Kancheva, A. K., Wardlaw, J. M., Lyall, D. M., Quinn, T. J. (2024) Clinical phenotypes associated with cerebral small vessel disease: an overview of systematic reviews. Neurology, 102, (doi: 10.1212/WNL.0000000000209267)

O’Callaghan, G., Fahy, M., O’Meara, S., Chawke, M., Waldron, E., Corry, M., Gallagher, S., Coyne, C., Lynch, J., Kennedy, E., Walsh, T., Cronin, H., Hannon, N., Fallon, C., Williams, D. J., Langhorne, P., Galvin, R., Horgan, F. (2024) Transitioning to home and beyond following stroke: a prospective cohort study of outcomes and needs. BMC Health Services Research, 24, pp. 449. (doi: 10.1186/s12913-024-10820-8)

Goeldlin, M. B. et al. (2024) Early vs late anticoagulation in minor, moderate, and major ischemic stroke with atrial fibrillation - an analysis of the ELAN randomized clinical trial. JAMA Neurology,

Mulholland, R.J., Manca, F., Ciminata, G., Quinn, T.J., Trotter, R., Pollock, K.G., Lister, S., Geue, C. (2024) Evaluating the effect of inequalities in oral anti-coagulant prescribing on outcomes in people with atrial fibrillation. European Heart Journal Open, (doi: 10.1093/ehjopen/oeae016)

Ciminata, G., Burton, J.K., Quinn, T.J., Geue, C. (2024) Understanding Pathways into Care-homes using Data (UnPiCD study): a two-part model to estimate inpatient and care-home costs using national linked health and social care data. BMC Health Services Research, 24, (doi: 10.1186/s12913-024-10675-z)

MacDonald, A. S. et al. (2024) Allopurinol and blood pressure variability following ischemic stroke and transient ischemic attack: a secondary analysis of XILO-FIST. Journal of Human Hypertension, (doi: 10.1038/s41371-024-00906-5)

Alghanimy, A., Work, L. M., Holmes, W. M. (2024) The glymphatic system and multiple sclerosis: An evolving connection. Multiple Sclerosis and Related Disorders, 83, (doi: 10.1016/j.msard.2024.105456)

Loughrey, C. et al. (2024) A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic action: Pre-clinical and phase I study. British Journal of Pharmacology,

Burton, J. K., McMinn, M., Vaughan, J. E., Nightingale, G., Fleuriot, J., Guthrie, B. (2024) Analysis of the impact of COVID-19 on Scotland’s care homes from March 2020 to October 2021: National linked data cohort analysis. Age and Ageing, 53, (doi: 10.1093/ageing/afae015)

Watt, J. K., Quinn, T. J. (2024) Critical Look at the NIHSS Visual Stimuli. Stroke, 55, pp. 452-453. (doi: 10.1161/strokeaha.123.045806)

Murphy, R. et al. (2024) Variations in the prevalence of atrial fibrillation, and in the strength of its association with ischemic stroke, in countries with different income levels: INTERSTROKE case–control study. International Journal of Stroke, (doi: 10.1177/17474930241227783)

Ali, M., Tibble, H., Brady, M. C., Quinn, T. J., Sunnerhagen, K. S., Venketasubramanian, N., Shuaib, A., Pandyan, A., Mead, G., on behalf of the VISTA collaboration, (2024) Validation of general pain scores from multidomain assessment tools in stroke. Frontiers in Neurology, 15, (doi: 10.3389/fneur.2024.1328832)

Mary, S., Conti-Ramsden, F., Boder, P., Parveen, H., Setjiadi, D., Fleminger, J., Brockbank, A., Graham, D., Bramham, K., Chappell, L. C., Delles, C. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6)

Irvine, L., Burton, J., Ali, M., Booth, J., Desborough, J., Logan, P., Moniz-Cook, E., Surr, C., Wright, D., Goodman, C. (2024) Data resource profile: the Virtual International Care Home Trials Archive (VICHTA) International Journal of Population Data Science, 8, (doi: 10.23889/ijpds.v8i6.2161)

McFall, A., Graham, D., Nicklin, S. A., Work, L. M. (2024) Unscheduled changes in pre-clinical stroke model housing contributes to variance in physiological and behavioural data outcomes: a post hoc analysis. Brain and Neuroscience Advances, 8, (doi: 10.1177/23982128241238934)

McMahon, D., Dixon, D., Quinn, T., Gallacher, K. I. (2024) The Acceptability of post-stroke cognitive testing through the lens of the theory of acceptability, a qualitative study. Cerebral Circulation - Cognition and Behavior, 6, (doi: 10.1016/j.cccb.2023.100197)

2023

Freeman-Jones, E., Miller, W. H., Work, L. M., Fullerton, J. L. (2023) Polypathologies and animal models of traumatic brain injury. Brain Sciences, 13, (doi: 10.3390/brainsci13121709)

Welsh, S. A., Hussey, K., Brittenden, J., Orr, D. J., Quinn, T. (2023) Frailty Assessment in Vascular OUtpatients Review (FAVOUR) PROTOCOL – single-centre prospective cohort study comparing feasibility and prognostic value of commonly used frailty assessment tools. BMJ Open, 13, (doi: 10.1136/bmjopen-2023-079387)

Taylor-Rowan, M., Alharthi, A., Noel-Storr, A. H., Myint, P. K., Stewart, C., McCleery, J., Quinn, T. J. (2023) Anticholinergic deprescribing interventions for reducing risk of cognitive decline or dementia in older adults with and without prior cognitive impairment. Cochrane Database of Systematic Reviews, 2023, (doi: 10.1002/14651858.CD015405.pub2)

Lyon, M., Fullerton, J. L., Kennedy, S., Work, L. M. (2023) Hypertension & dementia: pathophysiology & potential utility of antihypertensives in reducing disease burden. Pharmacology and Therapeutics, (doi: 10.1016/j.pharmthera.2023.108575)

Taylor-Rowan, M., Hafdi, M., Drozdowska, B., Elliott, E., Warlaw, J., Quinn, T. J. (2023) Physical and brain frailty in ischaemic stroke or TIA: shared occurrence and outcomes. A cohort study. European Stroke Journal, 8, pp. 1011-1020. (doi: 10.1177/23969873231186480)

Ali, M., Tibble, H., Brady, M. C., Quinn, T. J., Sunnerhagen, K. S., Venketasubramanian, N., Shuaib, A., Pandyan, A., Mead, G. (2023) Prevalence, trajectory and predictors of post stroke pain: retrospective analysis of pooled clinical trial datasets. Stroke, 54, pp. 3107-3116. (doi: 10.1161/STROKEAHA.123.043355)

Belch, J. J.F., Elder, A., Bartlett, S., Fardon, T., Flinn, K., Hughes, R. C., Miller, M. R., Newby, D., Quinn, T., Slater, M. (2023) Children are especially vulnerable to air pollution: We need data on transport emissions near schools. British Medical Journal, 383, (doi: 10.1136/bmj.p2675)

Miranda, F., Gonzalez, F., Plana, M. N., Zamora, J., Quinn, T. J., Seron, P. (2023) Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings. Cochrane Database of Systematic Reviews, 11, (doi: 10.1002/14651858.CD013126.pub2)

Hanratty, B., Wolters, A.T., Towers, A.M., Spilsbury, K., Meyer, J., Killett, A., Jones, L., Gordon, A., Burton, J.K., Akdur, G., Irvine, L., Warmoth, K., Liddle, J., Goodman, C. (2023) Data collection in care homes for older adults: A national survey in England. Journal of Long-Term Care, 2023, pp. 288-296. (doi: 10.31389/jltc.199)

Petermann-Rocha, F., Deo, S., Lyall, D., Orkaby, A. R., Quinn, T. J., Sattar, N., Celis-Morales, C., Pell, J. P., Ho, F. K. (2023) Association between the AHA Life's Essential 8 score and incident all-cause dementia: a prospective cohort study from UK Biobank. Current Problems in Cardiology, 48, (doi: 10.1016/j.cpcardiol.2023.101934)

Murphy, C. N., Delles, C., Davies, E., Connelly, P. J. (2023) Cardiovascular disease in transgender individuals. Atherosclerosis, 384, (doi: 10.1016/j.atherosclerosis.2023.117282)

Ho, L., Lloyd, K., Taylor-Rowan, M., Dawson, S., Logan, M., Leitc, S., Quinn, T. J., Shenkin, S. D., Parry, S. W., Jarman, H., Henderson, E. J. (2023) Comparing research priority-setting partnerships for older adults across international health care systems: a systematic review. Journal of the American Medical Directors Association, 24, pp. 1726-1745. (doi: 10.1016/j.jamda.2023.09.003)

Cooper, N., Germeni, E., Freeman, S. C., Jaiswal, N., Nevill, C. R., Sutton, A. J., Taylor-Rowan, M., Quinn, T. J. (2023) New horizons in evidence synthesis for older adults. Age and Ageing, 52, (doi: 10.1093/ageing/afad211)

Martin, T. P., MacDonald, E. A., Bradley, A., Watson, H., Saxena, P., Rog-Zielinska, E. A., Raheem, A., Fisher, S., Elbassioni, A. A. M., Almuzaini, O., Booth, C., Campbell, M., Riddell, A., Herzyk, P., Blyth, K., Nixon, C., Zentilin, L., Berry, C., Braun, T., Giacca, M., McBride, M. W., Nicklin, S. R., Cameron, E. R., Loughrey, C. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119, pp. 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107)

Sri, S. et al. (2023) A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia. Cerebral Circulation - Cognition and Behavior, 5, (doi: 10.1016/j.cccb.2023.100189)

Burton, J. K., Drummond, M., Gallacher, K. I., Quinn, T. J. (2023) Listening and learning: a qualitative study of Scottish care home staff experiences of managing COVID-19 between March 2020-August 2022. BMC Geriatrics, 23, (doi: 10.1186/s12877-023-04251-z)

Watt, J. K., Dickie, D. A., Lyall, D., Ward, J., Ho, F., Dawson, J., Quinn, T. J. (2023) Normative values of the brain health index in UK biobank. Neuroimage: Reports, 3, (doi: 10.1016/j.ynirp.2023.100176)

Kremer, C., Lorenzano, S., Bejot, Y., Lal, A., Epple, C., Gdovinova, Z., Mono, M.-L., Karapanayiotides, T., Jovanovic, D., Dawson, J., Caso, V. (2023) Sex differences in outcome after carotid revascularization in symptomatic and asymptomatic carotid artery stenosis. Journal of Vascular Surgery, 78, pp. 817-827.e10. (doi: 10.1016/j.jvs.2023.03.502)

MacKenzie, S. M., Birch, L. A., Lamprou, S., Rezvanisanijouybari, P., Fayad, M., Zennaro, M.-C., Davies, E. (2023) MicroRNAs in aldosterone production and action. Elsevier

Gray, S., Binmahfoz, A., Timraz, M., Quinn, T. J., Combet Aspray, E., Gray, S. R. (2023) The effect of long chain n-3 fatty acid supplementation on muscle strength in older adults: a systematic review and meta-analysis. Nutrients, 15, (doi: 10.3390/nu15163579)

Wood, K., Sardar, A., Eton, D. T., Mair, F. S., Kidd, L., Quinn, T. J., Gallacher, K. I. (2023) Adaptation and content validation of a patient-reported measure of treatment burden for use in stroke survivors: the patient experience with treatment and self-management in stroke (PETS-stroke) measure. Disability and Rehabilitation, (doi: 10.1080/09638288.2023.2241360)

Masoli, J. A.H., Todd, O., Burton, J. K., Wolff, C., Hewitt, J., Conroy, S., van Oppen, J., Wilkinson, C., Evans, R., Anand, A., Hollinghurst, J., Bhanu, C., Keevil, V., Vardy, E. (2023) New Horizons in the role of digital data in the healthcare of older people. Age and Ageing, 52, (doi: 10.1093/ageing/afad134)

Dawson, J., MacDonald, A. (2023) Sex and hypertensive organ damage: stroke. Journal of Human Hypertension, 37, pp. 644-648. (doi: 10.1038/s41371-023-00830-0)

Olivera, S., Graham, D. (2023) Sex differences in preclinical models of hypertension. Journal of Human Hypertension, 37, pp. 619-625. (doi: 10.1038/s41371-022-00770-1)

Kelbling, E., Ferreira Prescott, D., Shearer, M., Quinn, T. J. (2023) An assessment of the content and properties of extended and instrumental activities of daily living scales: a systematic review. Disability and Rehabilitation, (doi: 10.1080/09638288.2023.2224082)

Bernhardt, J., Churilov, L., Dewey, H., Donnan, G., Ellery, F., English, C. K., Gao, L., Hayward, K. S., Horgan, F., Indredavik, B., Johns, H., Langhorne, P., Lindley, R., Martins, S., Mohd Ali, K., Middleton, S., Moodie, M., Pandian, J. D., Parsons, B., Robinson, T., Srikanth, V., Thijs, V. (2023) A phase III, multi-arm multi-stage covariate-adjusted response-adaptive randomized trial to determine optimal early mobility training after stroke (AVERT DOSE) International Journal of Stroke, 18, pp. 745-750. (doi: 10.1177/17474930221142207)

Hanlon, P., Burton, J. K., Quinn, T. J., Mair, F. S., McAllister, D., Lewsey, J., Gallacher, K. I. (2023) Prevalence, measurement and implications of frailty in stroke survivors: an analysis of three global aging cohorts. International Journal of Stroke, 18, pp. 720-727. (doi: 10.1177/17474930231151847)

Youkee, D., Deen, G., Baldeh, M., Conteh, Z. F., Fox-Rushby, J., Gbessay, M., Johnson, J., Langhorne, P., Leather, A., Lisk, D. R., Marshall, I., O'Hara, J., Pessima, S., Rudd, A., Soley-Bori, M., Thompson, M., Wafa, H., Wang, Y., Watkins, C. L., Williams, C., Wolfe, C., Sackley, C. (2023) Stroke in Sierra Leone: case fatality rate and functional outcome after stroke in Freetown. International Journal of Stroke, 18, pp. 672-680. (doi: 10.1177/17474930231164892)

Fischer, U. et al. (2023) Early versus later anticoagulation for stroke with atrial fibrillation. New England Journal of Medicine, 388, pp. 2411-2421. (doi: 10.1056/NEJMoa2303048)

Habibi, J., Bosch, J., Bidulka, P., Belson, S., DePaul, V., Gandhi, D., Kumurenzi, A., Melifonwu, R., Pandian, J., Langhorne, P., Solomon, J. M., Dawar, D., Carroll, S., Urimubenshi, G., Kaddumukasa, M., Hamilton, L. (2023) Strategies for specialty training of healthcare professionals in low-resource settings: a systematic review on evidence from stroke care. BMC Medical Education, 23, (doi: 10.1186/s12909-023-04431-w)

Wightman, H., Quinn, T. J., Mair, F. S., Lewsey, J., McAllister, D. A., Hanlon, P. (2023) Frailty in randomised controlled trials for dementia or mild cognitive impairment measured via the frailty index: prevalence and prediction of serious adverse events and attrition. Alzheimer's Research and Therapy, 15, (doi: 10.1186/s13195-023-01260-3)

Gallacher, K. I., Taylor-Rowan, M., Eton, D. T., McLeod, H., Kidd, L., Wood, K., Sardar, A., Quinn, T. J., Mair, F. S. (2023) Protocol for the development and validation of a patient reported measure (PRM) of treatment burden in stroke. Health Open Research, 5, (doi: 10.12688/healthopenres.13334.1)

Misra, S., Quinn, T. J., Falcone, G. J., Sharma, V. K., de Havenon, A., Zhao, Y., Eldem, E., French, J. A., Yasuda, C. L., Dawson, J., Liebeskind, D. S., Kwan, P., Mishra, N. K. (2023) Impact of genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: a systematic review. European Journal of Neurology, 30, pp. 1791-1800. (doi: 10.1111/ene.15777)

Kumluang, S., Wu, O., Langhorne, P., Geue, C. (2023) Stroke resource utilisation and all-cause mortality in Thailand 2017–2020: a retrospective, cross-sectional study. BMJ Open, 13, (doi: 10.1136/bmjopen-2023-072259)

Dawson, J., Engineer, N. D., Cramer, S. C., Wolf, S. L., Ali, R., O'Dell, M. W., Pierce, D., Prudente, C. N., Redgrave, J., Feng, W., Liu, C. Y., Francisco, G. E., Brown, B. L., Dixit, A., Alecander, J., DeMark, L., Krishna, V., Kautz, S. A., Majid, A., Tarver, B., Turner, D. L., Kimberley, T. J. (2023) Vagus nerve stimulation paired with rehabilitation for upper limb motor impairment and function after chronic ischemic stroke: subgroup analysis of the randomized, blinded, pivotal, VNS-REHAB device trial. Neurorehabilitation and Neural Repair, 37, pp. 367-373. (doi: 10.1177/15459683221129274)

Cerullo, E., Sutton, A. J., Jones, H. E., Wu, O., Quinn, T. J., Cooper, N. J. (2023) MetaBayesDTA: codeless Bayesian meta-analysis of test accuracy, with or without a gold standard. BMC Medical Research Methodology, 23, (doi: 10.1186/s12874-023-01910-y)

Khan, M., Wasay, M., O'Donnell, M. J., Iqbal, R., Langhorne, P., Rosengren, A., Damasceno, A., Oguz, A., Lanas, F., Pogosova, N., Alhussain, F., Oveisgharan, S., Czlonkowska, A., Ryglewicz, D., Yusuf, S. (2023) Risk factors for stroke in the young (18-45 years): a case-control analysis of INTERSTROKE data from 32 countries. Neuroepidemiology, (doi: 10.1159/000530675)

Watt, J., Quinn, T. J. (2023) May literature synopsis. Stroke, 54, pp. e215-e216. (doi: 10.1161/STROKEAHA.123.042506)

Kelly, S., Cowan, A., Akdur, G., Irvine, L., Peryer, G., Welsh, S., Rand, S., Lang, I. A., Towers, A.-M., Spilsbury, K., Killett, A., Gordon, A. L., Hanratty, B., Jones, L., Meyer, J., Goodman, C., Burton, J. K. (2023) Outcome measures from international older adult care home intervention research: a scoping review. Age and Ageing, 52, (doi: 10.1093/ageing/afad069)

Faheem, W. et al. (2023) Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study. European Geriatric Medicine, 14, pp. 325-332. (doi: 10.1007/s41999-022-00737-y)

Naeem, F., Reid, J., Bailey, M., Reid, A., Smyth, C., Taylor-Rowan, M., Newman, E. J., Quinn, T. (2023) Pharmacological interventions for sialorrhoea in people with Parkinson's disease: a systematic review and meta-analysis. Movement Disorders Clinical Practice, 10, pp. 558-568. (doi: 10.1002/mdc3.13688)

Quinn, T. J., Muir, K. (2023) Do quality-of-life measures represent patient outcomes in stroke trials? Neurology, 100, pp. 597-598. (doi: 10.1212/WNL.0000000000206840)

Chouliara, N., Cameron, T., Byrne, A., Lewis, S., Langhorne, P., Robinson, T., Waring, J., Walker, M., Fisher, R. (2023) How do stroke early supported discharge services achieve intensive and responsive service provision? Findings from a realist evaluation study (WISE) BMC Health Services Research, 23, (doi: 10.1186/s12913-023-09290-1)

Fullerton, J., Bettencourt, C., Daniels, M., Mclean, F., Simpson, S., Smith, A., Woodling, N., Kerr, F. (2023) Creating connections: developing an online space for cross-regional mentorship and network building in the dementia research field. Health Open Research, 4, (doi: 10.12688/amrcopenres.13091.2)

Ward, K., Vail, A., Cameron, A., Katan, M., Lip, G. Y.H., Dawson, J., Smith, C. J., Kishore, A. K. (2023) Molecular biomarkers predicting newly detected atrial fibrillation after ischemic stroke or TIA: a systematic review. European Stroke Journal, 8, pp. 125-131. (doi: 10.1177/23969873221136927)

Kancheva, A., Quinn, T. J. (2023) Stroke literature synopsis (clinical) Stroke, 54, pp. e93-e94. (doi: 10.1161/STROKEAHA.122.042193)

Dawson, J. et al. (2023) Xanthine oxidase inhibition and white matter hyperintensity progression following ischaemic stroke and transient ischaemic attack (XILO-FIST): a multicentre, double-blinded, randomised, placebo-controlled trial. EClinicalMedicine, 57, (doi: 10.1016/j.eclinm.2023.101863)

Wu, Y. et al. (2023) Comparison of the accuracy of the 7-item HADS Depression subscale and 14-item total HADS for screening for major depression: A systematic review and individual participant data meta-analysis. Psychological Assessment, 35, pp. 95-114. (doi: 10.1037/pas0001181)

Leitch, S. L., Logan, M., Beishon, L., Quinn, T. J. (2023) International research priority setting exercises in stroke – systematic review. International Journal of Stroke, 18, pp. 133-143. (doi: 10.1177/17474930221096935)

Towers, A.-M., Gordon, A., Wolters, A. T., Allan, S., Rand, S., Webster, L. A., Crellin, E., Brine, R. J., De Corte, K., Akdur, G., Irvine, L., Burton, J., Hanratty, B., Killett, A., Meyer, J., Jones, L., Goodman, C. (2023) Piloting of a minimum data set for older people living in care homes in England: protocol for a longitudinal, mixed-methods study. BMJ Open, 13, (doi: 10.1136/bmjopen-2023-071686)

Smyth, A., O'Donnell, M., Rangarajan, S., Hankey, G. J., Oveisgharan, S., Canavan, M., McDermott, C., Xavier, D., Zhang, H., Damasceno, A., Avezum, A., Pogosova, N., Oguz, A., Ryglewicz, D., Iversen, H. K., Lanas, F., Rosengren, A., Yusuf, S., Langhorne, P. (2023) Alcohol intake as a risk factor for acute stroke: the INTERSTROKE Study. Neurology, 100, pp. e142-e153. (doi: 10.1212/WNL.0000000000201388)

Taylor-Rowan, M., Nafisi, S., Owen, R., Duffy, R., Patel, A., Burton, J. K., Quinn, T. J. (2023) Informant-based screening tools for dementia: an overview of systematic reviews. Psychological Medicine, 53, pp. 580-589. (doi: 10.1017/S0033291721002002)

Netzer, S., Chocano-Bedoya, P., Feller, M., Janett-Pellegri, C., Wildisen, L., Büchi, A. E., Moutzouri, E., Rodriguez, E. G., Collet, T.-H., Poortvliet, R. K.E., Mc Carthy, V. J.C., Aeberli, D., Aujesky, D., Westendorp, R., Quinn, T. J., Gussekloo, J., Kearney, P. M., Mooijaart, S., Bauer, D. C., Rodondi, N. (2023) The effect of thyroid hormone therapy on muscle function, strength and mass in older adults with subclinical hypothyroidism—an ancillary study within two randomized placebo controlled trials. Age and Ageing, 52, (doi: 10.1093/ageing/afac326)

Cameron, T. M., Koller, K., Byrne, A., Chouliara, N., Robinson, T., Langhorne, P., Walker, M., Fisher, R. J. (2023) A qualitative study exploring how stroke survivors' expectations and understanding of stroke Early Supported Discharge shaped their experience and engagement with the service. Disability and Rehabilitation, 45, pp. 2604-2611. (doi: 10.1080/09638288.2022.2102251)

2022

Kumluang, S., Geue, C., Langhorne, P., Wu, O. (2022) Availability of stroke services and hospital facilities at different hospital levels in Thailand: a cross-sectional survey study. BMC Health Services Research, 22, (doi: 10.1186/s12913-022-08922-2)

Lithgow, H., Johnston, L., Ho, F. K., Celis-Morales, C., Cobley, J., Raastad, T., Hunter, A. M., Lees, J. S., Mark, P. B., Quinn, T. J., Gray, S. R. (2022) Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle-damaging resistance exercise in young and older adults—the TAKEOVER study. Trials, 23, (doi: 10.1186/s13063-022-06937-y)

Taylor-Rowan, M., Alharthi, A. A., Noel-Storr, A. H., Myint, P. K., Stewart, C., McCleery, J., Quinn, T. J. (2022) Anticholinergic deprescribing interventions for reducing risk of cognitive decline or dementia in older adults with and without prior cognitive impairment. Cochrane Database of Systematic Reviews, 2022, (doi: 10.1002/14651858.cd015405)

Gerganova, G., Riddell, A., Miller, A. A. (2022) CNS border-associated macrophages in the homeostatic and ischaemic brain. Pharmacology and Therapeutics, 240, (doi: 10.1016/j.pharmthera.2022.108220)

Logan, M., Leitch, S., Bosakh, Z., Beishon, L., Quinn, T. J. (2022) Comparing international dementia research priorities—systematic review. International Journal of Geriatric Psychiatry, 37, (doi: 10.1002/gps.5836)

Fischer, U. et al. (2022) Early versus Late initiation of direct oral Anticoagulants in post-ischaemic stroke patients with atrial fibrillatioN (ELAN): Protocol for an international, multicentre, randomised-controlled, two-arm, open, assessor-blinded trial. European Stroke Journal, 7, pp. 487-495. (doi: 10.1177/23969873221106043)

Dawson, J., Abdul-Rahim, A. H. (2022) Paired vagus nerve stimulation for treatment of upper extremity impairment after stroke. International Journal of Stroke, 17, pp. 1061-1066. (doi: 10.1177/17474930221094684)

Lyko, C. et al. (2022) Thyroid antibodies and levothyroxine effects in subclinical hypothyroidism: a pooled analysis of two randomized controlled trials. Journal of Internal Medicine, 292, pp. 892-903. (doi: 10.1111/joim.13544)

Burton, J. K., Ciminata, G., Lynch, E., Shenkin, S. D., Geue, C., Quinn, T. J. (2022) Understanding Pathways into Care homes using Data (UnPiCD study): a retrospective cohort study using national linked health and social care data. Age and Ageing, 51, (doi: 10.1093/ageing/afac304)

Kumar, A. A., Yeo, N., Whittaker, M., Attra, P., Barrick, T. R., Bridges, L. R., Dickson, D. W., Esiri, M. M., Farris, C. W., Graham, D., Lin, W. L., Meijles, D. N., Pereira, A. C., Perry, G., Rosene, D. L., Shtaya, A. B., Van Agtmael, T., Zamboni, G., Hainsworth, A. H. (2022) Vascular collagen type-IV in hypertension and cerebral small vessel disease. Stroke, 53, pp. 3696-3705. (doi: 10.1161/STROKEAHA.122.037761)

Fischer, F., Levis, B., Falk, C., Sun, Y., Ioannidis, J. P. A., Cuijpers, P., Shrier, I., Benedetti, A., Thombs, B. D., , , , (2022) Comparison of different scoring methods based on latent variable models of the PHQ-9: an individual participant data meta-analysis. Psychological Medicine, 52, pp. 3472-3483. (doi: 10.1017/S0033291721000131)

Lim, S., Cox, N., Hale, M., White, L., Welch, C., Lochlainn, M. N., Burton, J. K., Richardson, S. J., Walesby, K., Willott, R., Makin, S., Taylor, J. (2022) Engagement in research during specialist geriatric medicine training: results of a national trainee survey. Clinical Medicine, 22, pp. 553-558. (doi: 10.7861/clinmed.2022-0283)

Byrne, A., Chouliara, N., Cameron, T., Geue, C., Lewis, S., Robinson, T., Langhorne, P., Walker, M. F., Fisher, R. J. (2022) Evaluating stroke early supported discharge using cost-consequence analysis. Disability and Rehabilitation, 44, pp. 7127-7133. (doi: 10.1080/09638288.2021.1983043)

McMahon, D., Micallef, C., Quinn, T. J. (2022) Review of clinical practice guidelines relating to cognitive assessment in stroke. Disability and Rehabilitation, 44, pp. 7632-7640. (doi: 10.1080/09638288.2021.1980122)

Mary, S., Boder, P., Padmanabhan, S., McBride, M. W., Graham, D., Delles, C., Dominiczak, A. F. (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888)

Verduri, A. et al. (2022) Comparison between first and second wave of COVID-19 outbreak in older people: the COPE multicentre European observational cohort study. European Journal of Public Health, 32, pp. 807-812. (doi: 10.1093/eurpub/ckac108)

Reel, P. S. et al. (2022) Machine learning for classification of hypertension subtypes using multi-omics: a multi-centre, retrospective, data-driven study. EBioMedicine, 84, (doi: 10.1016/j.ebiom.2022.104276)

Bilan, J., Aggrey, K., Quinn, T. J., Lumsden, J., Colquhoun, K. (2022) Occurrence and outcomes of possible superadded infections in older adults with COVID-19—cohort study. European Geriatric Medicine, 13, pp. 1161-1167. (doi: 10.1007/s41999-022-00675-9)

Carter, B., Keevil, V. L., Anand, A., Osuafor, C. N., Goudie, R. J.B., Preller, J., Lowry, M., Clunie, S., Shenkin, S. D., McCarthy, K., Hewitt, J., Quinn, T. J. (2022) The prognostic and discriminatory utility of the Clinical Frailty Scale and modified Frailty Index compared to age. Geriatrics, 7, (doi: 10.3390/geriatrics7050087)

Dawson, J., Bejot, Y., Christensen, L. M., De Marchis, G. M., Dichgans, M., Hagberg, G., Heldner, M. R., Milionis, H., Li, L., Pezzella, F. R., Taylor Rowan, M., Tiu, C., Webb, A. (2022) European Stroke Organisation (ESO) guideline on pharmacological interventions for long-term secondary prevention after ischaemic stroke or transient ischaemic attack. European Stroke Journal, 7, pp. I-XLI. (doi: 10.1177/23969873221100032)

Johnston, F. C., Cameron, A. C., Colquhoun, E., Murdoch, D. L., Dawson, J., Abdul-Rahim, A. H. (2022) Improving detection and management of atrial fibrillation after ischaemic stroke in Glasgow (IMPROVE-AF): a quality improvement project. Journal of the Royal College of Physicians of Edinburgh, 52, pp. 213-219. (doi: 10.1177/14782715221120133)

Cerullo, E., Jones, H. E., Carter, O., Quinn, T. J., Cooper, N. J., Sutton, A. J. (2022) Meta‐analysis of dichotomous and ordinal tests with an imperfect gold standard. Research Synthesis Methods, 13, pp. 595-611. (doi: 10.1002/jrsm.1567)

Pommer, G. et al. (2022) Preanalytical considerations and out-patient vs in-patient tests of plasma metanephrines to diagnose pheochromocytoma. Journal of Clinical Endocrinology and Metabolism, 107, pp. e3689-e3698. (doi: 10.1210/clinem/dgac390)

Dawson, J., Béjot, Y., Christensen, L. M., Marco De Marchis, G., Dichgans, M., Hagberg, G., Heldner, M. R., Milionis, H., Li, L., Pezzella, F. R., Taylor Rowan, M., Tiu, C., Webb, A. (2022) Response to letter by Prof Christian Nolte and colleagues. European Stroke Journal, 7, pp. 341-342. (doi: 10.1177/23969873221110378)

Quinn, T. J., Kelbling, E. (2022) September Literature Synopsis. Stroke, 53, pp. e429-e430. (doi: 10.1161/strokeaha.122.040206)

O’Callaghan, G., Fahy, M., Murphy, P., Langhorne, P., Galvin, R., Horgan, F. (2022) Effectiveness of interventions to support the transition home after acute stroke: a systematic review and meta-analysis. BMC Health Services Research, 22, (doi: 10.1186/s12913-022-08473-6)

Taylor-Rowan, M., Kraia, O., Kolliopoulou, C., Noel-Storr, A. H., Alharthi, A. A., Cross, A. J., Stewart, C., Myint, P. K., McCleery, J., Quinn, T. J. (2022) Anticholinergic burden for prediction of cognitive decline or neuropsychiatric symptoms in older adults with mild cognitive impairment or dementia. Cochrane Database of Systematic Reviews, 2022, (doi: 10.1002/14651858.cd015196.pub2)

Ball, E. L., Shah, M., Ross, E., Sutherland, R., Squires, C., Mead, G. E., Wardlaw, J., Quinn, T. J., Religa, D., Lundström, E., Cheyne, J., Shenkin, S. D. (2022) Predictors of post-stroke cognitive impairment using acute structural MRI neuroimaging: a systematic review and meta-analysis. International Journal of Stroke, (doi: 10.1177/17474930221120349)

Büchi, A. E., Feller, M., Netzer, S., Blum, M. R., Rodriguez, E. G., Collet, T.-H., Del Giovane, C., van Heemst, D., Quinn, T., Kearney, P. M., Westendorp, R. G. J., Gussekloo, J., Mooijaart, S., Hans, D., Bauer, D. C., Rodondi, N., Aeberli, D. (2022) Bone geometry in older adults with subclinical hypothyroidism upon levothyroxine therapy: a nested study within a randomized placebo controlled trial. Bone, 161, (doi: 10.1016/j.bone.2022.116404)

Bliziotis, N. G. et al. (2022) Preanalytical pitfalls in untargeted plasma nuclear magnetic resonance metabolomics of endocrine hypertension. Metabolites, 12, (doi: 10.3390/metabo12080679)

Reel, S. et al. (2022) Predicting hypertension subtypes with machine learning using targeted metabolites and their ratios. Metabolites, 12, (doi: 10.3390/metabo12080755)

Paciaroni, M. et al. (2022) Recurrent ischemic stroke and bleeding in patients with atrial fibrillation who suffered an acute stroke while on treatment with nonvitamin K antagonist oral anticoagulants: the RENO-EXTEND study. Stroke, 53, pp. 2620-2627. (doi: 10.1161/STROKEAHA.121.038239)

Broomfield, N. M., West, R., Barber, M., Quinn, T. J., Gillespie, D., Walters, M., House, A. (2022) TEARS: a longitudinal investigation of the prevalence, psychological associations and trajectory of poststroke emotionalism. Journal of Neurology, Neurosurgery and Psychiatry, 93, pp. 886-894. (doi: 10.1136/jnnp-2022-329042)

Kwan, J., Hafdi, M., Chiang, L. L. W., Myint, P. K., Wong, L. S., Quinn, T. J. (2022) Antithrombotic therapy to prevent cognitive decline in people with small vessel disease on neuroimaging but without dementia. Cochrane Database of Systematic Reviews, 2022, (doi: 10.1002/14651858.CD012269.pub2)

Drummond, M., Johnston, B., Quinn, T. J. (2022) Cutting through the intersections to care for caregivers: secondary data analysis of a carers support service in Glasgow, Scotland. Health and Social Care in the Community, 30, pp. 1334-1343. (doi: 10.1111/hsc.13463)

Ball, E. L., Sutherland, R., Squires, C., Mead, G. E., Religa, D., Lundström, E., Cheyne, J., Wardlaw, J. M., Quinn, T. J., Shenkin, S. D. (2022) Predicting post-stroke cognitive impairment using acute CT neuroimaging: a systematic review and meta-analysis. International Journal of Stroke, 17, pp. 618-627. (doi: 10.1177/17474930211045836)

Kishore, A. K., Hossain, M. J., Cameron, A., Dawson, J., Vail, A., Smith, C. J. (2022) Use of risk scores for predicting new atrial fibrillation after ischemic stroke or transient ischemic attack—A systematic review. International Journal of Stroke, 17, pp. 608-617. (doi: 10.1177/17474930211045880)

Gdovinova, Z., Kremer, C., Lorenzano, S., Dawson, J., Lal, A., Caso, V. (2022) Aspirin for primary stroke prevention; evidence for a differential effect in men and women. Frontiers in Neurology, 13, (doi: 10.3389/fneur.2022.856239)

Kremer, C., Gdovinova, Z., Bejot, Y., Heldner, M. R., Zuurbier, S., Walter, S., Lal, A., Epple, C., Lorenzano, S., Mono, M.-L., Karapanayiotides, T., Krishnan, K., Jovanovic, D., Dawson, J., Caso, V. (2022) European Stroke Organisation guidelines on stroke in women: Management of menopause, pregnancy and postpartum. European Stroke Journal, 7, pp. I-XIX. (doi: 10.1177/23969873221078696)

Esteban-Cornejo, I., Ho, F., Petermann-Rocha, F., Lyall, D. M., Martinez-Gomez, D., Cabanas-Sanchez, V., Ortega, F. B., Hillman, C. H., Gill, J. M.R., Quinn, T. J., Sattar, N., Pell, J. P., Gray, S. R., Celis-Morales, C. (2022) Handgrip strength and all-cause dementia incidence and mortality: findings from the UK Biobank prospective cohort study. Journal of Cachexia, Sarcopenia and Muscle, 13, pp. 1514-1525. (doi: 10.1002/jcsm.12857)

Du Puy, R. S., Poortvliet, R. K. E., Mooijaart, S. P., Stott, D. J., Quinn, T., Sattar, N., Westendorp, R. G. J., Kearney, P. M., McCarthy, V. J. C., Byrne, S., Rodondi, N., Baretella, O., Collet, T.-H., van Heemst, D., Dekkers, O. M., Jukema, J. W., Smit, J. W. A., Gussekloo, J., den Elzen, W. P. J. (2022) No effect of levothyroxine on hemoglobin in older adults with subclinical hypothyroidism: pooled results from 2 randomized controlled trials. Journal of Clinical Endocrinology and Metabolism, 107, pp. e2339-e2347. (doi: 10.1210/clinem/dgac106)

Fullerton, J. L., Thomas, J. M., Gonzalez-Trueba, L., Trivett, C., Van Kralingen, J. C., Allan, S. M., Quinn, T. J., Work, L. M. (2022) Systematic review: association between circulating microRNA expression & stroke. Journal of Cerebral Blood Flow and Metabolism, 42, pp. 935-951. (doi: 10.1177/0271678X221085090)

Alkhedhairi, S. A.A., Aba Alkhayl, F. F., Ismail, A. D., Rozendaal, A., German, M., MacLean, B., Johnston, L., Miller, A.A., Hunter, A.M., Macgregor, L.J., Combet, E., Quinn, T.J., Gray, S.R. (2022) The effect of krill oil supplementation on skeletal muscle function and size in older adults: a randomised controlled trial. Clinical Nutrition, 41, pp. 1228-1235. (doi: 10.1016/j.clnu.2022.04.007)

O'Donnell, M. J. et al. (2022) Association of Lipids, Lipoproteins, and Apolipoproteins with Stroke Subtypes in an International Case Control Study (INTERSTROKE) Journal of Stroke, 24, pp. 224-235. (doi: 10.5853/jos.2021.02152)

van Rijssel, A. E., Stins, B. C., Beishon, L. C., Sanders, M. L., Quinn, T. J., Claassen, J. A.H.R., de Heus, R. A.A. (2022) Effect of antihypertensive treatment on cerebral blood flow in older adults: a systematic review and meta-analysis. Hypertension, 79, pp. 1067-1078. (doi: 10.1161/HYPERTENSIONAHA.121.18255)

He, W. et al. (2022) Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size. Cardiovascular Research, 118, pp. 1535-1547. (doi: 10.1093/cvr/cvab204)

Malfait, F., Forlino, A., Sengle, G., Van Agtmael, T. (2022) Editorial: molecular mechanisms of heritable connective tissue disorders. Frontiers in Genetics, 13, (doi: 10.3389/fgene.2022.866665)

Fullerton, J. L., Cosgrove, C. C., Rooney, R. A., Work, L. (2022) Extracellular vesicles and their microRNA cargo in ischaemic stroke. Journal of Physiology, (doi: 10.1113/JP282050)

Beishon, L. C., Elliott, E., Hietamies, T. M., Mc Ardle, R., O'Mahony, A., Elliott, A. R., Quinn, T. J. (2022) Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia. Cochrane Database of Systematic Reviews, 2022, (doi: 10.1002/14651858.cd013724.pub2)

Taylor-Rowan, M., McGuire, L., Hafdi, M., Evans, J., Stott, D. J., Wetherall, K., Elliott, E., Drozdowska, B., Quinn, T. J. (2022) Comparative validity of informant tools for assessing pre-stroke cognitive impairment. International Journal of Geriatric Psychiatry, 37, pp. 1-10. (doi: 10.1002/gps.5700)

Ritchie, C. W., Waymont, J. M. J., Pennington, C., Draper, K., Borthwick, A., Fullerton, N., Chantler, M., Porteous, M. E., Danso, S. O., Green, A., McWhirter, L., Muniz Terrera, G., Simpson, S., Thompson, G., Trépel, D., Quinn, T.J., Kilgour, A. (2022) The Scottish Brain Health Service Model: rationale and scientific basis for a national care pathway of brain health services in Scotland. Journal of Prevention of Alzheimer's Disease, 9, pp. 348-358. (doi: 10.14283/jpad.2021.63)

Peryer, G., Kelly, S., Blake, J., Burton, J. K., Irvine, L., Cowan, A., Akdur, G., Killett, A., Brand, S. L., Musa, M. K., Meyer, J., Gordon, A. L., Goodman, C. (2022) Contextual factors influencing complex intervention research processes in care homes: a systematic review and framework synthesis. Age and Ageing, 51, (doi: 10.1093/ageing/afac014)

Burton, J. K., Wolters, A. T., Towers, A.-M., Jones, L., Meyer, J., Gordon, A. L., Irvine, L., Hanratty, B., Spilsbury, K., Peryer, G., Rand, S., Killett, A., Akdur, G., Allan, S., Biswas, P., Goodman, C. (2022) Developing a minimum data set for older adult care homes in the UK: exploring the concept and defining early core principles. Lancet Healthy Longevity, 3, pp. e186-e193. (doi: 10.1016/S2666-7568(22)00010-1)

Brady, M. C. et al. (2022) Dosage, intensity, and frequency of language therapy for aphasia: a systematic review–based, individual participant data network meta-analysis. Stroke, 53, pp. 956-967. (doi: 10.1161/STROKEAHA.121.035216)

Burton, J. K., Stewart, J., Blair, M., Oxley, S., Wass, A., Taylor-Rowan, M., Quinn, T. J. (2022) Prevalence and implications of frailty in acute stroke: systematic review & meta-analysis. Age and Ageing, 51, (doi: 10.1093/ageing/afac064)

Alexander, J., Dawson, J., Langhorne, P. (2022) Dynamic hand orthoses for the recovery of hand and arm function in adults after stroke: a systematic review and meta-analysis of randomised controlled trials. Topics in Stroke Rehabilitation, 29, pp. 114-124. (doi: 10.1080/10749357.2021.1878669)

Carter, B. et al. (2022) Prognostic value of estimated glomerular filtration rate in hospitalised older patients (over 65) with COVID-19: a multicentre, European, observational cohort study. BMC Geriatrics, 22, (doi: 10.1186/s12877-022-02782-5)

Chong, M. R., Narula, S., Morton, R., Judge, C., Akhabir, L., Cawte, N., Pathan, N., Lali, R., Mohammadi-Shemirani, P., Shoamanesh, A., O'Donnell, M., Yusuf, S., Langhorne, P., Pare, G. (2022) Mitochondrial DNA copy number as a marker and mediator of stroke prognosis: observational and Mendelian randomization analyses. Neurology, 98, pp. e470-e482. (doi: 10.1212/WNL.0000000000013165)

Joyce, N., Atkinson, T., Mc Guire, K., Wiggam, M. I., Gordon, P. L., Kerr, E. L., Patterson, C. E., McILmoyle, J., Roberts, G. E., Flynn, P. A., Burns, P., Rennie, I. R., Taylor-Rowan, M., Quinn, T. J., Fearon, P. (2022) Frailty and stroke thrombectomy outcomes—an observational cohort study. Age and Ageing, 51, (doi: 10.1093/ageing/afab260)

Craig, L., Hoo, Z. L., Yan, T. Z., Wardlaw, J., Quinn, T. J. (2022) Prevalence of dementia in ischaemic or mixed stroke populations: systematic review and meta-analysis. Journal of Neurology, Neurosurgery and Psychiatry, 93, pp. 180-187. (doi: 10.1136/jnnp-2020-325796)

Ciminata, G., Geue, C., Wu, O., Deidda, M., Kreif, N., Langhorne, P. (2022) Propensity score methods for comparative-effectiveness analysis: a case study of direct oral anticoagulants in the atrial fibrillation population. PLoS ONE, 17, (doi: 10.1371/journal.pone.0262293)

Smyth, A., O’Donnell, M., Hankey, G. J., Rangarajan, S., Lopez-Jaramillo, P., Xavier, D., Zhang, H., Canavan, M., Damasceno, A., Langhorne, P., Avezum, A., Pogosova, N., Oguz, A., Yusuf, S. (2022) Anger or emotional upset and heavy physical exertion as triggers of stroke: the INTERSTROKE study. European Heart Journal, 43, pp. 202-209. (doi: 10.1093/eurheartj/ehab738)

Musa, M. K., Akdur, G., Brand, S., Killett, A., Spilsbury, K., Peryer, G., Burton, J. K., Gordon, A. L., Hanratty, B., Towers, A.- M., Irvine, L., Kelly, S., Jones, L., Meyer, J., Goodman, C. (2022) The uptake and use of minimum data sets (MDS) for older people living and dying in care homes: a realist review. BMC Geriatrics, 22, (doi: 10.1186/s12877-021-02705-w)

Kidd, L., Duncan Millar, J., Mason, H., Quinn, T., Gallacher, K. I., Jones, F., Fisher, R. J., Lebedis, T., Barber, M., Brennan, K., Smith, M. (2022) Supported self-management in community stroke rehabilitation: what is it and how does it work? A protocol for a realist evaluation study. BMJ Open, 12, (doi: 10.1136/bmjopen-2021-055491)

Baig, S. S., Kamarova, M., Ali, A., Su, L., Dawson, J., Redgrave, J. N., Majid, A. (2022) Transcutaneous vagus nerve stimulation (tVNS) in stroke: the evidence, challenges and future directions. Autonomic Neuroscience, 237, (doi: 10.1016/j.autneu.2021.102909)

Dekkers, R., Carey, L., Langhorne, P. (2022) Making Literature Reviews Work: A Multidisciplinary Guide to Systematic Approaches. Springer

Lyall, D. M., Quinn, T., Lyall, L. M., Ward, J., Anderson, J. J., Smith, D. J., Stewart, W., Strawbridge, R. J., Bailey, M. E.S., Cullen, B. (2022) Quantifying bias in psychological and physical health in the UK Biobank imaging sub-sample. Brain Communications, 4, (doi: 10.1093/braincomms/fcac119)

Quinn, T. J., Taylor-Rowan, M., Elliott, E., Drozdowska, B., McMahon, D., Broomfield, N. M., Barber, M., MacLeod, M. J., Cvoro, V., Byrne, A., Ross, S., Crow, J., Slade, P., Dawson, J., Langhorne, P. (2022) Research protocol – Assessing Post-Stroke Psychology Longitudinal Evaluation (APPLE) study: a prospective cohort study in stroke. Cerebral Circulation - Cognition and Behavior, 3, (doi: 10.1016/j.cccb.2022.100042)

Armignacco, R. et al. (2022) Whole blood methylome-derived features to discriminate endocrine hypertension. Clinical Epigenetics, 14, (doi: 10.1186/s13148-022-01347-y)

2021

Petermann-Rocha, F., Lyall, D. M., Gray, S. R., Gill, J. M.R., Sattar, N., Welsh, P., Quinn, T. J., Stewart, W., Pell, J. P., Ho, F. K., Celis-Morales, C. (2021) Dose-response association between device-measured physical activity and incident dementia: a prospective study from UK Biobank. BMC Medicine, 19, (doi: 10.1186/s12916-021-02172-5)

Crowe, K., Quinn, T. J., Mark, P. B., Findlay, M. D. (2021) “Is it removed during dialysis?”—cognitive dysfunction in advanced kidney failure—a review article. Frontiers in Neurology, 12, (doi: 10.3389/fneur.2021.787370)

Omar, R., Malfait, F., Van Agtmael, T. (2021) Four decades in the making: collagen III and mechanisms of vascular Ehlers Danlos Syndrome. Matrix Biology Plus, 12, (doi: 10.1016/j.mbplus.2021.100090)

Kulkarni, S., Welsh, P., Ali, M., Petrie, J. R. (2021) Quality of life in people with type 2 diabetes; a study in a multi-ethnic clinical trial population. British Journal of Diabetes, 21, pp. 210-215. (doi: 10.15277/bjd.2021.315)

Mary, S., Boder, P., Rossitto, G., Graham, L., Scott, K., Flynn, A., Kipgen, D., Graham, D., Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135, pp. 2749-2761. (doi: 10.1042/CS20211017)

Taylor-Rowan, M., Kraia, O., Kolliopoulou, C., Cross, A. J., Stewart, C., Myint, P. K., McCleery, J., Quinn, T. J. (2021) Anticholinergic burden for prediction of cognitive decline or neuropsychiatric symptoms in older adults with mild cognitive impairment or dementia (Protocol) Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.cd015196)

Zuber, V., Cameron, A., Myserlis, E. P., Bottolo, L., Fernandez‐Cadenas, I., Burgess, S., Anderson, C. D., Dawson, J., Gill, D. (2021) Leveraging genetic data to elucidate the relationship between COVID‐19 and ischemic stroke. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.121.022433)

Cameron, A., Cheng, H. K., Lee, R.-P., Doherty, D., Hall, M., Khashayar, P., Lip, G., Quinn, T., Abdul-Rahim, A., Dawson, J. (2021) Biomarkers for atrial fibrillation detection after stroke: systematic review and meta-analysis. Neurology, 97, pp. e1775-e1789. (doi: 10.1212/WNL.0000000000012769)

McCleery, J., Quinn, T. J. (2021) Aducanumab and the certainty of evidence. Age And Ageing, 50, pp. 1899-1900. (doi: 10.1093/ageing/afab167)

MacKenzie, S. M., Saunders, H., van Kralingen, J. C., Robertson, S., Riddell, A., Zennaro, M.-C., Davies, E. (2021) Circulating microRNAs as diagnostic markers in primary aldosteronism. Cancers, 13, (doi: 10.3390/cancers13215312)

Fisher, R. J., Chouliara, N., Byrne, A., Cameron, T., Lewis, S., Langhorne, P., Robinson, T., Waring, J., Geue, C., Paley, L., Rudd, A., Walker, M. F. (2021) Large-scale implementation of stroke early supported discharge: the WISE realist mixed-methods study. Health Services and Delivery Research, 9, (doi: 10.3310/hsdr09220)

Burton, J. K., Craig, L., Yong, S. Q., Siddiqi, N., Teale, E. A., Woodhouse, R., Barugh, A. J., Shepherd, A. M., Brunton, A., Freeman, S. C., Sutton, A. J., Quinn, T. J. (2021) Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.CD013307.pub3)

Burton, J. K., Walker, M. F. (2021) Supporting stroke survivors living in care homes: challenges and opportunities for practice development and research. Age and Ageing, 50, pp. 1901-1903. (doi: 10.1093/ageing/afab180)

Marshall-McKenna, R., Campbell, E., Ho, F., Banger, M., Ireland, J., Rowe, P., McAlpine, C., McArthur, K., Quinn, T. J., Gray, S. R. (2021) Resistance exercise training at different loads in frail and healthy older adults: a randomised feasibility trial. Experimental Gerontology, 153, (doi: 10.1016/j.exger.2021.111496)

Burton, J. K., McMinn, M., Vaughan, J. E., Fleuriot, J., Guthrie, B. (2021) Care-home outbreaks of COVID-19 in Scotland March to May 2020: national linked data cohort analysis. Age and Ageing, 50, pp. 1482-1492. (doi: 10.1093/ageing/afab099)

Webb, A., Werring, D., Dawson, J., Rothman, A., Lawson, A., Wartolowska, K. (2021) Design of a randomised, double-blind, crossover, placebo-controlled trial of effects of sildenafil on cerebrovascular function in small vessel disease: Oxford haemodynamic adaptation to reduce pulsatility trial (OxHARP) European Stroke Journal, 6, pp. 283-290. (doi: 10.1177/23969873211026698)

Quinn, T. J., Richard, E., Teuschl, Y., Gattringer, T., Hafdi, M., O’Brien, J. T., Merriman, N., Gillebert, C., Huyglier, H., Verdelho, A., Schmidt, R., Ghaziani, E., Forchammer, H., Pendlebury, S. T., Bruffaerts, R., Mijajlovic, M., Drozdowska, B. A., Ball, E., Markus, H. S. (2021) European Stroke Organisation (ESO) and European Academy Neurology (EAN) joint guidelines on post stroke cognitive impairment. European Stroke Journal, 6, pp. I-XXXVIII. (doi: 10.1177/23969873211042192)

Pokhilko, A., Brezzo, G., Handunnetthi, L., Heilig, R., Lennon, R., Smith, C., Allan, S. M., Granata, A., Sinha, S., Wang, T., Markus, H. S., Naba, A., Fischer, R., Van Agtmael, T., Horsburgh, K., Cader, M. Z. (2021) Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease. Journal of Cerebral Blood Flow and Metabolism, 41, pp. 2423-2438. (doi: 10.1177/0271678X211004307)

Alexander, J., Langhorne, P., Kidd, L., Wu, O., McConnachie, A., van Wijck, F., Dawson, J. (2021) SaeboGlove therapy for upper limb disability and severe hand impairment after stroke (SUSHI): study protocol for a randomised controlled trial. European Stroke Journal, 6, pp. 302-310. (doi: 10.1177/23969873211036586)

Alves-Lopes, R., Montezano, A. C., Neves, K. B., Harvey, A., Rios, F. J., Skiba, D. S., Arendse, L. B., Guzik, T. J., Graham, D., Poglitsch, M., Sturrock, E., Touyz, R. M. (2021) Selective inhibition of the C-domain of ACE (angiotensin-converting enzyme) combined with inhibition of NEP (neprilysin): a potential new therapy for hypertension. Hypertension, 78, pp. 604-616. (doi: 10.1161/HYPERTENSIONAHA.121.17041)

Quin, T. J., Burton, J. K., Carter, B., Cooper, N., Dwan, K., Field, R., Freeman, S. C., Gue, C., Hsieh, P.-H., McGill, K., Nevill, C. R., Rana, D., Sutton, A., Taylor-Rowan, M., Xin, Y. (2021) Correction to: Following the science? Comparison of methodological and reporting quality of covid-19 and other research from the first wave of the pandemic. BMC Medicine, 19, (doi: 10.1186/s12916-021-02073-7)

Patanapirunhakit, P., Karlsson, H., Mulder, M., Ljunggren, S., Graham, D., Freeman, D. (2021) Sphingolipids in HDL – potential markers for adaptation to pregnancy? Biochimica et Biophysica Acta: Molecular and Cell Biology of Lipids, 1866, (doi: 10.1016/j.bbalip.2021.158955)

Boland, E., Quondamatteo, F., Van Agtmael, T. (2021) The role of basement membranes in cardiac biology and disease. Bioscience Reports, 41, pp. BSR20204185. (doi: 10.1042/bsr20204185)

Chung, J. et al. (2021) Rare missense functional variants at COL4A1 and COL4A2 in sporadic intracerebral hemorrhage. Neurology, 97, pp. e236-e247. (doi: 10.1212/WNL.0000000000012227)

Randles, M., Lausecker, F., Kong, Q., Suleiman, H., Reid, G., Kolatsi-Joannou, M., Tian, P., Falcone, S., Davenport, B., Potter, P., Van Agtmael, T., Norman, J., Long, D., Humphries, M., Miner, J., Lennon, R. (2021) Identification of an altered matrix signature in kidney aging and disease. Journal of the American Society of Nephrology, 32, pp. 1713-1732. (doi: 10.1681/ASN.2020101442)

Burton, J. K., Reid, M., Gribben, C., Caldwell, D., Clark, D.N., Hanlon, P., Quinn, T. J., Fischbacher, C., Knight, P., Guthrie, B., McAllister, D. (2021) Impact of COVID-19 on care-home mortality and life expectancy in Scotland. Age and Ageing, 50, pp. 1029-1037. (doi: 10.1093/ageing/afab080)

Burton, J. K., Craig, L. E., Yong, S. Q., Siddiqi, N., Teale, E. A., Woodhouse, R., Barugh, A. J., Sheperd, A. M., Brunton, A., Freeman, S. C., Sutton, A. J., Quinn, T. J. (2021) Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.CD013307.pub2)

Reuten, R. et al. (2021) Basement membrane stiffness determines metastases formation. Nature Materials, 20, pp. 892-903. (doi: 10.1038/s41563-020-00894-0)

Dawson, J., Merwick, Á., Webb, A., Dennis, M., Ferrari, J., Fonseca, A. C. (2021) European Stroke Organisation expedited recommendation for the use of short-term dual antiplatelet therapy early after minor stroke and high-risk TIA. European Stroke Journal, 6, pp. CLXXXVII-CXCI. (doi: 10.1177/23969873211000877)

Alshuhri, M. S., Gallagher, L., Work, L., Holmes, W. (2021) Direct imaging of glymphatic flow using H217O MRI. JCI Insight, 6, (doi: 10.1172/jci.insight.141159)

Geriatric Medicine Research Collaborative, et al. (2021) Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study. Age and Ageing, 50, pp. 617-630. (doi: 10.1093/ageing/afab026)

Taylor-Rowan, M., Edwards, S., Noel-Storr, A. H., McCleery, J., Myint, P. K., Soiza, R., Stewart, C., Loke, Y. K., Quinn, T. J. (2021) Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.CD013540.pub2)

Schofield, C. L., Rodrigo-Navarro, A., Dalby, M. J., Van Agtmael, T., Salmeron-Sanchez, M. (2021) Biochemical­­– and biophysical–induced barriergenesis in the blood brain barrier: a review of barriergenic factors for use in in vitro models. Advanced NanoBiomed Research, 1, (doi: 10.1002/anbr.202000068)

Dean, A., Van Agtmael, T. (2021) Collagen IV-related diseases and therapies. Springer

Abzhandadze, T., Lundström, E., Buvarp, D., Eriksson, M., Quinn, T. J., Sunnerhagen, K. S. (2021) Development of a short-form Swedish version of the Montreal Cognitive Assessment (s-MoCA-SWE): protocol for a cross-sectional study. BMJ Open, 11, (doi: 10.1136/bmjopen-2021-049035)

Fernandez-Garcia, C., Ternent, L., Homer, T. M., Rodgers, H., Bosomworth, H., Shaw, L., Aird, L., Andole, S., Cohen, D., Dawson, J., Finch, T., Ford, G., Francis, R., Hogg, S., Hughes, N., Krebs, H.I., Price, C., Turner, D., Van Wijck, F., Wilkes, S., Wilson, N., Vale, L. (2021) Economic evaluation of robot-assisted training versus an enhanced upper limb therapy programme or usual care for patients with moderate or severe upper limb functional limitation due to stroke: results from the RATULS randomised controlled trial. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-042081)

Dawson, J., Liu, C. Y., Francisco, G. E., Cramer, S. C., Wolf, S. L., Dixit, A., Alexander, J., Ali, R., Brown, B. L., Feng, W., DeMark, L., Hochberg, L. R., Kautz, S. A., Majid, A., O'Dell, M. W., Pierce, D., Prudente, C. N., Redgrave, J., Turner, D. L., Engineer, N. D., Kimberley, T. J. (2021) Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial. Lancet, 397, pp. 1545-1553. (doi: 10.1016/S0140-6736(21)00475-X)

Scott, K., Morgan, H. L., Delles, C., Fisher, S., Graham, D., McBride, M. W. (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53, pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020)

Paciaroni, M. et al. (2021) Risk factors for intracerebral hemorrhage in patients with atrial fibrillation on NOACs for stroke prevention. Stroke, 52, pp. 1450-1454. (doi: 10.1161/STROKEAHA.120.031827)

Perry, R. J., Smith, C. J., Roffe, C., Simister, R. J., Narayanamoorthi, S., Marigold, R., Willmot, M., Dixit, A., Hassan, A., Quinn, T., Ankolekar, S., Zhang, L., Banerjee, S., Ahmed, U., Padmanabhan, N., Ferdinand, P., McGrane, F., Banaras, A., Marks, I. H., Werring, D. J., SETICOS collaborators, . (2021) Characteristics and outcomes of COVID-19-associated stroke: a UK multicentre case-control study. Journal of Neurology, Neurosurgery and Psychiatry, 92, pp. 242-248. (doi: 10.1136/jnnp-2020-324927)

Drozdowska, B. A., McGill, K., McKay, M., Bartlam, R., Langhorne, P., Quinn, T. J. (2021) Prognostic rules for predicting cognitive syndromes following stroke: a systematic review. European Stroke Journal, 6, pp. 18-27. (doi: 10.1177/2396987321997045)

Wardlaw, J. M., Doubal, F., Brown, R., Backhouse, E., Woodhouse, L., Bath, P., Quinn, T. J., Robinson, T., Markus, H. S., McManus, R., O’Brien, J. T., Werring, D. J., Sprigg, N., Parry-Jones, A., Touyz, R. M., Williams, S., Mah, Y.-H., Emsley, H. (2021) Rates, risks and routes to reduce vascular dementia (R4vad), a UK-wide multicentre prospective observational cohort study of cognition after stroke: protocol. European Stroke Journal, 6, pp. 89-101. (doi: 10.1177/2396987320953312)

Quinn, T. J., Burton, J. K., Carter, B., Cooper, N., Dwan, K., Field, R., Freeman, S. C., Geue, C., Hsieh, P.-H., McGill, K., Nevill, C. R., Rana, D., Sutton, A., Taylor Rowan, M., Xin, Y. (2021) Following the Science? Comparison of methodological and reporting quality of covid-19 and other research from the first wave of the pandemic. BMC Medicine, 19, (doi: 10.1186/s12916-021-01920-x)

Irvine, L., Burton, J. K., Ali, M., Quinn, T. J., Goodman, C. (2021) Protocol for the development of a repository of individual participant data from randomised controlled trials conducted in adult care homes (The Virtual International Care Homes Trials Archive (VICHTA)) Trials, 22, (doi: 10.1186/s13063-021-05107-w)

Battle, C. E., Abdul-Rahim, A., Shenkin, S. D., Hewitt, J., Quinn, T. (2021) Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta‐analysis. Cochrane Database of Systematic Reviews, 2, (doi: 10.1002/14651858.CD013306.pub2)

Schnabel, S., van Wijck, F., Bain, B., Barber, M., Dall, P., Fleming, A., Kerr, A., Langhorne, P., McConnachie, A., Molloy, K., Stanley, B., Young, H., Kidd, L. (2021) Experiences of augmented arm rehabilitation including supported self-management after stroke: a qualitative investigation. Clinical Rehabilitation, 35, pp. 288-301. (doi: 10.1177/0269215520956388)

Duncan Millar, J., van Wijck, F., Pollock, A., Ali, M. (2021) International consensus recommendations for outcome measurement in poststroke arm rehabilitation trials. European Journal of Physical and Rehabilitation Medicine, 57, pp. 61-68. (doi: 10.23736/S1973-9087.20.06575-2)

Gill, D., Cameron, A. C., Burgess, S., Liu, X., Doherty, D. J., Karhunen, V., Abdul-Rahim, A., Taylor-Rowan, M., Zuber, V., Tsao, P. S., Klarin, D., VA Million Veteran Program, , Evangelou, E., Elliott, P., Damrauer, S. M., Quinn, T. J., Dehghan, A., Theodoratou, E., Dawson, J., Tzoulaki, I. (2021) Urate, blood pressure, and cardiovascular disease: evidence from Mendelian randomization and meta-analysis of clinical trials. Hypertension, 77, pp. 383-392. (doi: 10.1161/HYPERTENSIONAHA.120.16547)

Stewart, C., Yrjana, K., Kishor, M., Soiza, R. L., Taylor-Rowan, M., Quinn, T. J., Loke, Y. K., Myint, P. K. (2021) Anticholinergic burden measures predict older people's physical function and quality of life: a systematic review. Journal of the American Medical Directors Association, 22, pp. 56-64. (doi: 10.1016/j.jamda.2020.05.065)

Fisher, R. J., Byrne, A., Chouliara, N., Lewis, S., Paley, L., Hoffman, A., Rudd, A., Robinson, T., Langhorne, P., Walker, M. (2021) Effect of stroke early supported discharge on length of hospital stay: analysis from a national stroke registry. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-043480)

MacRae, C., Henderson, D. A.G., Mercer, S. W., Burton, J., De Sousa, N., Grill, P., Marwick, C., Guthrie, B. (2021) Excessive polypharmacy and potentially inappropriate prescribing in 147 care homes: a cross-sectional study. BJGP Open, 5, pp. BJGPO.2021.0167. (doi: 10.3399/BJGPO.2021.0167)

McCallum, L., Brooksbank, K., McConnachie, A., Aman, A., Lip, S., Dawson, J., MacIntyre, I. M., MacDonald, T. M., Webb, D. J., Padmanabhan, S. (2021) Rationale and design of the genotype-blinded trial of torasemide for the treatment of hypertension (BHF UMOD) American Journal of Hypertension, 34, pp. 92-99. (doi: 10.1093/ajh/hpaa166)

Grill, P., Marwick, C., De Souza, N., Burton, J. K., Hughes, C., Guthrie, B. (2021) The burden of psychotropic and anticholinergic medicines use in care homes: population-based analysis in 147 care homes. Age and Ageing, 50, pp. 183-189. (doi: 10.1093/ageing/afaa122)

Stewart, C., Taylor-Rowan, M., Soiza, R. L., Quinn, T. J., Loke, Y. K., Myint, P. K. (2021) Anticholinergic burden measures and older people’s falls risk: a systematic prognostic review. Therapeutic Advances in Drug Safety, 12, pp. 20420986211016645. (doi: 10.1177/20420986211016645)

Farina, N., Suemoto, C. K., Burton, J. K., Oliveira, D., Frost, R. (2021) Perceptions of dementia amongst the general public across Latin America: a systematic review. Aging and Mental Health, 25, pp. 787-796. (doi: 10.1080/13607863.2020.1725738)

2020

Paciaroni, M. et al. (2020) Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes. European Stroke Journal, 5, pp. 374-383. (doi: 10.1177/2396987320937116)

McFall, A., Nicklin, S. A., Work, L. M. (2020) The counter regulatory axis of the renin angiotensin system in the brain and ischaemic stroke: insight from preclinical stroke studies and therapeutic potential. Cellular Signalling, 76, (doi: 10.1016/j.cellsig.2020.109809)

Pashova, A., Work, L.M., Nicklin, S.A. (2020) The role of extracellular vesicles in neointima formation post vascular injury. Cellular Signalling, 76, (doi: 10.1016/j.cellsig.2020.109783)

Taylor-Rowan, M., Nafisi, S., Burton, J. K., Quinn, T. J. (2020) Informant-based screening tools for diagnosis of dementia, an overview of systematic reviews of test accuracy studies protocol. Systematic Reviews, 9, (doi: 10.1186/s13643-020-01530-3)

Beazer, J. D., Patanapirunhakit, P., Gill, J. M.R., Graham, D., Karlsson, H., Ljunggren, S., Mulder, M., Freeman, D. J. (2020) High-density lipoprotein’s vascular protective functions in metabolic and cardiovascular disease - could extracellular vesicles be at play? Clinical Science, 134, pp. 2977-2986. (doi: 10.1042/CS20200892)

Musa, M. K., Akdur, G., Hanratty, B., Kelly, S., Gordon, A., Peryer, G., Spilsbury, K., Killett, A., Burton, J., Meyer, J., Fortescue, S., Towers, A.-M., Irvine, L., Goodman, C. (2020) Uptake and use of a minimum data set (MDS) for older people living and dying in care homes in England: a realist review protocol. BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040397)

Lim, A., Singhal, S., Lavallee, P., Amarenco, P., Rothwell, P. M., Albers, G., Sharma, M., Brown Jr, R., Ranta, A., Maddula, M., Kleinig, T., Dawson, J., Elkind, M. S.V., Guarino, M., Coutts, S. B., Clissold, B., Ma, H., Phan, T. (2020) An international report on the adaptations of rapid transient ischaemic attack pathways during the COVID-19 pandemic. Journal of Stroke and Cerebrovascular Diseases, 29, (doi: 10.1016/j.jstrokecerebrovasdis.2020.105228)

Richardson, S. J., Carroll, C. B., Close, J., Gordon, A. L., O'Brien, J., Quinn, T. J., Rochester, L., Sayer, A. A., Shenkin, S. D., van der Velde, N., Woo, J., Witham, M. D. (2020) Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities. Age and Ageing, 49, pp. 901-906. (doi: 10.1093/ageing/afaa149)

Langhorne, P., Audebert, H. J., Cadilhac, D. A., Kim, J., Lindsay, P. (2020) Stroke systems of care in high-income countries: what is optimal? Lancet, 396, pp. 1433-1442. (doi: 10.1016/S0140-6736(20)31363-5)

Burton, J. K., Bayne, G., Evans, C., Garbe, F., Gorman, D., Honhold, N., McCormick, D., Othieno, R., Stevenson, J., Swietlik, S., Templeton, K. E., Tranter, M., Willocks, L., Guthrie, B. (2020) Evolution and effects of COVID-19 outbreaks in care homes: a population analysis in 189 care homes in one geographical region of the UK. Lancet Healthy Longevity, 1, pp. E21-E31. (doi: 10.1016/S2666-7568(20)30012-X)

Carter, B., Collins, J.T., Barlow-Pay, F., Rickard, F., Bruce, E., Verduri, A., Quinn, T.J., Mitchell, E., Price, A., Vilches-Moraga, A., Stechman, M.J., Short, R., Einarsson, A., Braude, P., Moug, S., Myint, P.K., Hewitt, J., Pearce, L., McCarthy, K., , , on behalf of the COPE Study Collaborators, (2020) Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial study (COVID in Older PEople) Journal of Hospital Infection, 106, pp. 376-384. (doi: 10.1016/j.jhin.2020.07.013)

Burton, J.K., Goodman, C., Guthrie, B., Gordon, A.L., Hanratty, B., Quinn, T.J. (2020) Closing the UK care home data gap - methodological challenges and solutions. International Journal of Population Data Sciences, 5, (doi: 10.23889/ijpds.v5i4.1391)

Ganesh, A., Taylor-Rowan, M., Quinn, T. J. (2020) Reader response: Outcomes of patients with stroke treated with thrombolysis according to prestroke Rankin Scale scores. Neurology, 95, pp. 506-507. (doi: 10.1212/WNL.0000000000010516)

Ngandu Mpoyi, E., Cantini, M., Sin, Y. Y., Fleming, L., Zhou, D. W., Costell, M., Lu, Y., Kadler, K., García, A. J., Van Agtmael, T., Salmeron-Sanchez, M. (2020) Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts. Biomaterials, 252, (doi: 10.1016/j.biomaterials.2020.120090)

Todd, O. M., Burton, J. K., Dodds, R. M., Hollinghurst, J., Lyons, R. A., Quinn, T. J., Schneider, A., Walesby, K. E., Wilkinson, C., Conroy, S., Gale, C. P., Hall, M., Walters, K., Clegg, A. P. (2020) New horizons in the use of routine data for ageing research. Age and Ageing, 49, pp. 716-722. (doi: 10.1093/ageing/afaa018)

Collins, J. T., Short, R., Carter, B., Verduri, A., Myint, P. K., Quinn, T. J., Vilches-Moraga, A., Stechman, M. J., Moug, S., McCarthy, K., Hewitt, J. (2020) The clinical frailty scale: estimating the prevalence of frailty in older patients hospitalised with COVID-19. The COPE study. Geriatrics, 5, (doi: 10.3390/geriatrics5030058)

Rossitto, G., Mary, S., Chen, J. Y., Bodder, P., Chew, K. S., Neves, K. B., Alves, R. L., Montezano, A. C., Welsh, P., Petrie, M. C., Graham, D., Touyz, R. M., Delles, C. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, (doi: 10.1038/s41467-020-17820-2)

Fisher, R. J., Byrne, A., Chouliara, N., Lewis, S., Paley, L., Hoffman, A., Rudd, A., Robinson, T., Langhorne, P., Walker, M. F. (2020) Effectiveness of stroke early supported discharge. Circulation: Cardiovascular Quality and Outcomes, 13, (doi: 10.1161/circoutcomes.119.006395)

Hewitt, J., Carter, B., Vilches-Moraga, A., Quinn, T. J., Braude, P., Verduri, A., Pearce, L., Stechman, M., Short, R., Price, A., Collins, J. T., Bruce, E., Einarsson, A., Rickard, F., Mitchell, E., Holloway, M., Hesford, J., Barlow-Pay, F., Clini, E., Myint, P. K., Moug, S. J., McCarthy, K., on behalf of the COPE Study Collaborators, . (2020) The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study. Lancet Public Health, 5, pp. e444-e451. (doi: 10.1016/S2468-2667(20)30146-8)

Drozdowska, B. A., Elliott, E., Taylor-Rowan, M., Shaw, R. C., Cuthbertson, G., Langhorne, P., Quinn, T. J. (2020) Cardiovascular risk factors indirectly affect acute post-stroke cognition through stroke severity and prior cognitive impairment: A moderated mediation analysis. Alzheimer's Research and Therapy, 12, (doi: 10.1186/s13195-020-00653-y)

McFall, A. et al. (2020) UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: questionnaire and workshop proceedings. Journal of Cerebral Blood Flow and Metabolism, 40, pp. 1402-1414. (doi: 10.1177/0271678X20910552)

Riddell, A., McBride, M., Braun, T., Nicklin, S. A., Cameron, E., Loughrey, C. M., Martin, T. P. (2020) RUNX1: an emerging therapeutic target for cardiovascular disease. Cardiovascular Research, 116, pp. 1410-1423. (doi: 10.1093/cvr/cvaa034)

Dawson, J., Engineer, N. D., Prudente, C. N., Pierce, D., Francisco, G., Yozbatiran, N., Tarver, W. B., Casavant, R., Kline, D. K., Cramer, S. C., Van de Winckel, A., Kimberley, T. J. (2020) Vagus nerve stimulation paired with upper-limb rehabilitation after stroke: one-year follow-up. Neurorehabilitation and Neural Repair, 34, pp. 609-615. (doi: 10.1177/1545968320924361)

Hanratty, B., Burton, J. K., Goodman, C., Gordon, A. L., Spilsbury, K. (2020) Covid-19 and lack of linked datasets for care homes. British Medical Journal, 369, (doi: 10.1136/bmj.m2463)

de Montmollin, M., Feller, M., Beglinger, S., McConnachie, A., Aujesky, D., Collet, T.-H., Ford, I., Gussekloo, J., Kearney, P. M., McCarthy, V. J.C., Mooijaart, S., Poortvliet, R. K.E., Quinn, T., Stott, D. J., Watt, T., Westendorp, R., Rodondi, N., Bauer, D. C. (2020) L-thyroxine therapy for older adults with subclinical hypothyroidism and hypothyroid symptoms: secondary analysis of a randomized trial. Annals of Internal Medicine, 172, pp. 709-716. (doi: 10.7326/M19-3193)

Walters, R., Collier, J. M., Braighi Carvalho, L., Langhorne, P., Katijjahbe, M. A., Tan, D., Moodie, M., Bernhardt, J. (2020) Exploring post acute rehabilitation service use and outcomes for working age stroke survivors (≤65 years) in Australia, UK and South East Asia: data from the international AVERT trial. BMJ Open, 10, (doi: 10.1136/bmjopen-2019-035850)

Cadilhac, D. A. et al. (2020) Improving economic evaluations in stroke: a report from the ESO Health Economics Working Group. European Stroke Journal, 5, pp. 184-192. (doi: 10.1177/2396987319897466)

Levis, B. et al. (2020) Patient Health Questionnaire-9 scores do not accurately estimate depression prevalence: individual participant data meta-analysis. Journal of Clinical Epidemiology, 122, pp. 115-128.e1. (doi: 10.1016/j.jclinepi.2020.02.002)

Mentel, A., Quinn, T. J., Cameron, A. C., Lees, K. R., Abdul-Rahim, A. H. (2020) The impact of atrial fibrillation type on the risks of thromboembolic recurrence, mortality and major haemorrhage in patients with previous stroke: a systematic review and meta-analysis of observational studies. European Stroke Journal, 5, pp. 155-168. (doi: 10.1177/2396987319896674)

Burton, J. K., Yates, L. C., Whyte, L., Fitzsimmons, E., Stott J, D. (2020) New horizons in iron deficiency anaemia in older adults. Age and Ageing, 49, pp. 309-318. (doi: 10.1093/ageing/afz199)

Graves-Morris, K., Stewart, C., Soiza, R. L., Taylor-Rowan, M., Quinn, T. J., Loke, Y. K., Myint, P. K. (2020) The prognostic value of anticholinergic burden measures in relation to mortality in older individuals: a systematic review and meta-analysis. Frontiers in Pharmacology, 11, (doi: 10.3389/fphar.2020.00570)

Nosalski, R., Siedlinski, M., Denby, L., Mcginnigle, E., Nowak, M., Nguyen Dinh Cat, A., Medina-Ruiz, L., Cantini, M., Skiba, D., Wilk, G., Osmenda, G., Rodor, J., Salmeron-Sanchez, M., Graham, G., Maffia, P., Graham, D., Baker, A. H., Guzik, T. J. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428)

Frazier, S., McBride, M. W., Mulvana, H., Graham, D. (2020) From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia. Clinical Science, 134, pp. 1001-1025. (doi: 10.1042/CS20200023)

Ciminata, G., Geue, C., Langhorne, P., Wu, O. (2020) A two-part model to estimate inpatient, outpatient, prescribing and care home costs associated with atrial fibrillation in Scotland. BMJ Open, 10, (doi: 10.1136/bmjopen-2018-028575)

Hanlon, P., Quinn, T. J., Gallacher, K. I., Myint, P. K., Jani, B. D., Nicholl, B. I., Lowrie, R., Soiza, R. L., Neal, S. R., Lee, D., Mair, F. S. (2020) Assessing risks of polypharmacy involving medications with anticholinergic properties. Annals of Family Medicine, 18, pp. 148-155. (doi: 10.1370/afm.2501)

Quinn, T. J., Myint, P. K., McCleery, J., Taylor-Rowan, M., Stewart, C. (2020) Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome. Cochrane Database of Systematic Reviews, 2020, (doi: 10.1002/14651858.cd013540)

Baylan, S., Haig, C., MacDonald, M., Stiles, C., Easto, J., Thomson, M., Cullen, B., Quinn, T. J., Stott, D. J., Mercer, S. W., Broomfield, N. M., Murray, H., Evans, J. J. (2020) Measuring the Effects of Listening for Leisure on Outcome after stroke (MELLO): a pilot randomised controlled trial of mindful music listening. International Journal of Stroke, 15, pp. 149-158. (doi: 10.1177/1747493019841250)

Parikh, N. S., Kamel, H., Navi, B. B., Iadecola, C., Merkler, A. E., Jesudian, A., Dawson, J., Falcone, G. J., Sheth, K. N., Roh, D. J., Elkind, M. S.V., Hanley, D. F., Ziai, W. C., Murthy, S. B. (2020) Liver fibrosis indices and outcomes after primary intracerebral hemorrhage. Stroke, 51, pp. 830-837. (doi: 10.1161/STROKEAHA.119.028161)

Dickie, D. A., Gardner, K., Wagener, A., Wyss, A., Arba, F., Wardlaw, J. M., Dawson, J. (2020) Cortical thickness, white matter hyperintensities, and cognition after stroke. International Journal of Stroke, 15, pp. 46-54. (doi: 10.1177/1747493019851291)

Lim, S., Oh, T. J., Dawson, J., Sattar, N. (2020) Diabetes drugs and stroke risk: intensive versus conventional glucose‐lowering strategies, and implications of recent cardiovascular outcome trials. Diabetes, Obesity and Metabolism, 22, pp. 6-15. (doi: 10.1111/dom.13850)

McArthur, L., Riddell, A., Chilton, L., Smith, G. L., Nicklin, S. A. (2020) Regulation of connexin 43 by interleukin 1β in adult rat cardiac fibroblasts and effects in an adult rat cardiac myocyte: fibroblast co-culture model. Heliyon, 6, (doi: 10.1016/j.heliyon.2019.e03031)

Marshall-Mckenna, R., Campbell, E., Ho, F., Banger, M., Rowe, P., McAlpine, C., McArthur, K., Quinn, T. J., Gray, S. R. (2020) Feasibility of resistance exercise to failure at different loads in frail and healthy older adults?

Brady, M. C. et al. (2020) RELEASE: a protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia. Aphasiology, 34, pp. 137-157. (doi: 10.1080/02687038.2019.1643003)

2019

Geriatric Medicine Research Collaborative, ., , , , , , , , (2019) Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: results of a prospective multi-centre study on World Delirium Awareness Day. BMC Medicine, 17, (doi: 10.1186/s12916-019-1458-7)

Kishore, A. K., Jeans, A. R., Garau, J., Bustamante, A., Kalra, L., Langhorne, P., Chamorro, A., Urra, X., Katan, M., Di Napoli, M., Westendorp, W., Nederkoorn, P. J., van de Beek, D., Roffe, C., Woodhead, M., Montaner, J., Meisel, A., Smith, C. J. (2019) Antibiotic treatment for pneumonia complicating stroke: recommendations from the pneumonia in stroke consensus (PISCES) group. European Stroke Journal, 4, pp. 318-328. (doi: 10.1177/2396987319851335)

Drummond, M., Johnston, B., Quinn, T. J. (2019) Measuring the success of interventions for caregivers: a focussed systematic review. Current Opinion in Supportive and Palliative Care, 13, pp. 351-359. (doi: 10.1097/SPC.0000000000000461)

Mooijaart, S. P., Du Puy, R. S., Stott, D. J., Kearney, P. M., Rodondi, N., Westendorp, R. G. J., den Elzen, W. P. J., Postmus, I., Poortvliet, R. K. E., van Heemst, D., van Munster, B. C., Peeters, R. P., Ford, I., Kean, S., Messow, C.-M., Blum, M. R., Collet, T.-H., Watt, T., Dekkers, O. M., Jukema, J. W., Smit, J. W. A., Langhorne, P., Gussekloo, J. (2019) Association between levothyroxine treatment and thyroid-related symptoms among adults aged 80 years and older with subclinical hypothyroidism. JAMA: Journal of the American Medical Association, 322, pp. 1977-1986. (doi: 10.1001/jama.2019.17274)

Dickie, D. A., Kimberley, T. J., Pierce, D., Engineer, N., Tarver, W. B., Dawson, J. (2019) An exploratory study of predictors of response to vagus nerve stimulation paired with upper-limb rehabilitation after ischemic stroke. Scientific Reports, 9, (doi: 10.1038/s41598-019-52092-x)

McDonald, M. W., Black, S. E., Copland, D. A., Corbett, D., Dijkhuizen, R. M., Farr, T. D., Jeffers, M. S., Kalaria, R. N., Karayanidis, F., Leff, A. P., Nithianantharajah, J., Pendlebury, S., Quinn, T. J., Clarkson, A. N., O’Sullivan, M. J. (2019) Cognition in stroke rehabilitation and recovery research: consensus-based core recommendations from the second Stroke Recovery and Rehabilitation Roundtable. Neurorehabilitation and Neural Repair, 33, pp. 943-950. (doi: 10.1177/1545968319886444)

Shaw, R., Drozdowska, B., Taylor-Rowan, M., Elliott, E., Cuthbertson, G., Stott, D. J., Quinn, T. J. (2019) Delirium in an acute stroke setting, occurrence, and risk factors. Stroke, 50, pp. 3265-3268. (doi: 10.1161/strokeaha.119.025993)

Shaw, R. C., Walker, G., Elliott, E., Quinn, T. J. (2019) Occurrence rate of delirium in acute stroke settings. Stroke, 50, pp. 3028-3036. (doi: 10.1161/strokeaha.119.025015)

McDicken, J. A., Elliott, E., Blayney, G., Makin, S., Ali, M., Larner, A. J., Quinn, T. J. (2019) Accuracy of the short-form Montreal Cognitive Assessment: systematic review and validation. International Journal of Geriatric Psychiatry, 34, pp. 1515-1525. (doi: 10.1002/gps.5162)

van Kralingen, J., McFall, A., Ord, E. N.J., Coyle, T. F., Bissett, M., McClure, J. D., McCabe, C., Macrae, I. M., Dawson, J., Work, L. M. (2019) Altered extracellular vesicle microrna expression in ischemic stroke and small vessel disease. Translational Stroke Research, 10, pp. 495-508. (doi: 10.1007/s12975-018-0682-3)

McDonald, M. W., Black, S. E., Copland, D. A., Corbett, D., Dijkhuizen, R. M., Farr, T. D., Jeffers, M. S., Kalaria, R. N., Karayanidis, F., Leff, A. P., Nithianantharajah, J., Pendlebury, S., Quinn, T. J., Clarkson, A. N., O’Sullivan, M. J. (2019) Cognition in stroke rehabilitation and recovery research: Consensus-based core recommendations from the second Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke, 14, pp. 774-782. (doi: 10.1177/1747493019873600)

Deuchar, G. A., Van Kralingen, J. C., Work, L. M., Santosh, C., Muir, K. W., McCabe, C., Macrae, I. M. (2019) Preclinical validation of the therapeutic potential of Glasgow Oxygen Level Dependent (GOLD) technology: A theranostic for acute stroke. Translational Stroke Research, 10, pp. 583-595. (doi: 10.1007/s12975-018-0679-y)

Becker, C. E., Quinn, T. J., Williams, A. (2019) Association between endothelial cell stabilizing medication and small vessel disease stroke: a case-control study. Frontiers in Neurology, 10, (doi: 10.3389/fneur.2019.01029)

Gallacher, K., Quinn, T., Kidd, L., Eton, D., Elliot, J., Johnston, N., Erwin, P. J., Mair, F. (2019) Systematic review of patient-reported measures of treatment burden in stroke. BMJ Open, 9, (doi: 10.1136/bmjopen-2019-029258)

Chan, C. C.H., Fage, B. A., Burton, J. K., Smailagic, N., Gill, S. S., Herrmann, N., Nikolaou, V., Quinn, T. J., Noel-Storr, A. H., Seitz, D. P. (2019) Mini-Cog for the diagnosis of Alzheimer’s disease dementia and other dementias within a secondary care setting. Cochrane Database of Systematic Reviews, 9, (doi: 10.1002/14651858.CD011414.pub2)

Efstathiadou, A., Gill, D., McGrane, F., Quinn, T., Dawson, J. (2019) Genetically determined uric acid and the risk of cardiovascular and neurovascular diseases: a Mendelian randomization study of outcomes investigated in randomized trials. Journal of the American Heart Association, 8, (doi: 10.1161/JAHA.119.012738)

Gatseva, A., Sin, Y. Y., Brezzo, G., Van Agtmael, T. (2019) Basement membrane collagens and disease mechanisms. Essays in Biochemistry, 63, pp. 297-312. (doi: 10.1042/EBC20180071)

Hurford, R., Vail, A., Heal, C., Ziai, W. C., Dawson, J., Murthy, S. B., Wang, X., Anderson, C. S., Hanley, D. F., Parry-Jones, A. R. (2019) Oedema extension distance in intracerebral haemorrhage: Association with baseline characteristics and long-term outcome. European Stroke Journal, 4, pp. 263-270. (doi: 10.1177/2396987319848203)

Pickford, C. G., Findlow, A. H., Kerr, A., Banger, M., Clarke-Cornwell, A. M., Hollands, K. L., Quinn, T., Granat, M. H. (2019) Quantifying sit-to-stand and stand-to-sit transitions in free-living environments using the activPAL thigh-worn activity monitor. Gait and Posture, 73, pp. 140-146. (doi: 10.1016/j.gaitpost.2019.07.126)

Elliott, E., Drozdowska, B. A., Taylor-Rowan, M., Shaw, R. C., Cuthbertson, G., Quinn, T. J. (2019) Who is classified as untestable on brief cognitive screens in an acute stroke setting? Diagnostics, 9, (doi: 10.3390/diagnostics9030095)

Cumming, T. B., Churilov, L., Collier, J., Donnan, G., Ellery, F., Dewey, H., Langhorne, P., Lindley, R. I., Moodie, M., Thrift, A. G., Bernhardt, J. (2019) Early mobilization and quality of life after stroke: findings from AVERT. Neurology, 93, pp. e717-e728. (doi: 10.1212/WNL.0000000000007937)

Al-Shahi Salman, R. et al. (2019) Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial. Lancet Neurology, 18, pp. 643-652. (doi: 10.1016/S1474-4422(19)30184-X)

Rodgers, H., Bosomworth, H., Krebs, H. I., van Wijck, F., Howel, D., Wilson, N., Aird, L., Alvarado, N., Andole, S., Cohen, D. L., Dawson, J., Fernandez-Garcia, C., Finch, T., Ford, G. A., Francis, R., Hogg, S., Hughes, N., Price, C. I., Ternent, L., Turner, D. L., Vale, L., Wilkes, S., Shaw, L. (2019) Robot Assisted Training for the Upper Limb after Stroke (RATULS): a multi-centre randomised controlled trial. Lancet, 394, pp. 51-62. (doi: 10.1016/S0140-6736(19)31055-4)

Bernhardt, J., Collier, J. M., Bate, P., Thuy, M. N.T., Langhorne, P. (2019) Very early versus delayed mobilization after stroke: systematic review and meta-analysis. Stroke, 50, pp. e178-e179. (doi: 10.1161/strokeaha.119.024502)

Al-Shahi Salman, R. et al. (2019) Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial. Lancet, 393, pp. 2613-2623. (doi: 10.1016/S0140-6736(19)30840-2)

Fisher, R., Chouliara, N., Byrne, A., Lewis, S., Langhorne, P., Robinson, T., Waring, J., Geue, C., Hoffman, A., Paley, L., Rudd, A., Walker, M. (2019) What is the impact of large-scale implementation of stroke Early Supported Discharge? A mixed methods realist evaluation study protocol. Implementation Science, 14, (doi: 10.1186/s13012-019-0908-0)

English, C., Bayley, M., Hill, K., Langhorne, P., Molag, M., Ranta, A., Solomon, J. M., Turner, T., Campbell, B. C.V. (2019) Bringing stroke clinical guidelines to life. International Journal of Stroke, 14, pp. 337-339. (doi: 10.1177/1747493019833015)

Mikolajczyk, T. P., Nosalski, R., Skiba, D. S., Koziol, J., Mazur, M., Justo Junior, A. S., Kowalczyk, P., Kusmierczyk, Z., Schramm Luc, A., Luc, K., Maffia, P., Graham, D., Kiss, A. K., Naruszewicz, M., Guzik, T. J. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176, pp. 1951-1965. (doi: 10.1111/bph.14583)

Kinch, K., Fullerton, J. L., Stewart, W. (2019) One-hundred years (and counting) of blast-associated traumatic brain injury. Journal of the Royal Army Medical Corps, 165, pp. 180-182. (doi: 10.1136/jramc-2017-000867)

Quinn, T. J., Drozdowska, B. A. (2019) Stroke prediction and the future of prognosis research. Nature Reviews Neurology, 15, pp. 311-312. (doi: 10.1038/s41582-019-0181-5)

Czesnikiewicz-Guzik, M., Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D., Harrison, D. G., Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176, pp. 1922-1931. (doi: 10.1111/bph.14536)

Donaldson, A. I.C., Neal, S. R., McAlpine, C. H., Quinn, T., Shenkin, S. D., Ellis, G., Myint, P. K. (2019) Variation in acute and community service provision of care of the elderly services across Scotland: findings from the Scottish Care of Older People (SCoOP) initial scoping survey. Journal of the Royal College of Physicians of Edinburgh, 49, pp. 105-111. (doi: 10.4997/JRCPE.2019.204)

Pollock, A., Hazelton, C., Rowe, F. J., Jonuscheit, S., Kernohan, A., Angilley, J., Henderson, C. A., Langhorne, P., Campbell, P. (2019) Interventions for visual field defects in people with stroke. Cochrane Database of Systematic Reviews, 5, (doi: 10.1002/14651858.CD008388.pub3)

Tsiachristas, A., Ellis, G., Buchanan, S., Langhorne, P., Stott J, D., Shepperd, S. (2019) Should I stay or should I go? A retrospective propensity score-matched analysis using administrative data of hospital-at-home for older people in Scotland. BMJ Open, 9, (doi: 10.1136/bmjopen-2018-023350)

Wyss, A., Dawson, J., Arba, F., Wardlaw, J. M., Dickie, D. A. (2019) Combining neurovascular and neurodegenerative magnetic resonance imaging measures in stroke. Stroke, 50, pp. 1136-1139. (doi: 10.1161/STROKEAHA.118.024181)

McDermid, I., Barber, M., Dennis, M., Langhorne, P., Macleod, M. J., McAlpine, C. H., Quinn, T. J. (2019) Home-time is a feasible and valid stroke outcome measure in national datasets. Stroke, 50, pp. 1282-1285. (doi: 10.1161/STROKEAHA.118.023916)

Taylor-Rowan, M., Keir, R., Cuthbertson, G., Shaw, R., Drozdowska, B., Elliott, E., Evans, J., Stott J, D., Quinn, T. J. (2019) Pre-stroke frailty is independently associated with post-stroke cognition: A cross-sectional study. Journal of the International Neuropsychological Society, 25, pp. 501-506. (doi: 10.1017/S1355617719000092)

Olson, E., Pravenec, M., Landa, V., Koh-Tan, H. H. C., Dominiczak, A. F., McBride, M. W., Graham, D. (2019) Transgenic overexpression of glutathione S-transferase μ-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 37, pp. 985-996. (doi: 10.1097/HJH.0000000000001960)

Woodhouse, R., Burton, J. K., Rana, N., Pang, Y. L., Lister, J. E., Siddiqi, N. (2019) Interventions for preventing delirium in older people in institutional long-term care. Cochrane Database of Systematic Reviews, 4, (doi: 10.1002/14651858.CD009537.pub3)

Freeman, S. C., Kerby, C. R., Patel, A., Cooper, N. J., Quinn, T., Sutton, A. J. (2019) Development of an interactive web-based tool to conduct and interrogate meta-analysis of diagnostic test accuracy studies: MetaDTA. BMC Medical Research Methodology, 19, (doi: 10.1186/s12874-019-0724-x)

Burton, J. K., Siddiqi, N., Teale, E. A., Barugh, A., Sutton, A. J. (2019) Non-pharmacological interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database of Systematic Reviews, 2019, (doi: 10.1002/14651858.CD013307)

Battle, C. E., Abdul-Rahim, A. H., Shenkin, S. D., Hewitt, J., Quinn, T. J. (2019) Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a networkmeta-analysis (Protocol) Cochrane Database of Systematic Reviews, 4, (doi: 10.1002/14651858.CD013306)

Ugusman, A. B., Riddell, A., Kennedy, S. (2019) Effect of peroxynitrite (ONOO−) on the function of murine perivascular adipose tissue. Pharmacology and Pharmacy, 10, pp. 194-204. (doi: 10.4236/pp.2019.104017)

Duncan Millar, J., van Wijck, F., Pollock, A., Ali, M. (2019) Outcome measures in post-stroke arm rehabilitation trials: do existing measures capture outcomes that are important to stroke survivors, carers, and clinicians? Clinical Rehabilitation, 33, pp. 737-749. (doi: 10.1177/0269215518823248)

Engineer, N. D., Kimberley, T. J., Prudente, C. N., Dawson, J., Tarver, W. B., Hays, S. A. (2019) Targeted vagus nerve stimulation for rehabilitation after stroke. Frontiers in Neuroscience, 13, (doi: 10.3389/fnins.2019.00280)

Drozdowska, B. A., Singh, S., Quinn, T. J. (2019) Thinking about the future: a review of prognostic scales used in acute stroke. Frontiers in Neurology, 10, (doi: 10.3389/fneur.2019.00274)

Hanley, D. F. et al. (2019) Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. Lancet, 393, pp. 1021-1032. (doi: 10.1016/S0140-6736(19)30195-3)

Beishon, L. C., Batterham, A. P., Quinn, T. J., Nelson, C. P., Panerai, R. B., Robinson, T., Haunton, V. J. (2019) Addenbrooke’s Cognitive Examination III (ACE-III) and mini-ACE for the detection of dementia and mild cognitive impairment. Cochrane Database of Systematic Reviews, 3, (doi: 10.1002/14651858.cd013282)

Hendry, K., Green, C., McShane, R., Noel-Storr, A. H., Stott J, D. J., Anwer, S., Sutton, A. J., Burton, J. K., Quinn, T. J. (2019) AD-8 for detection of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 3, (doi: 10.1002/14651858.CD011121.pub2)

Elliott, E., Haldane, D., Quinn, T. J. (2019) Pitfalls of neurocognitive testing in an occupational medical setting. Occupational Medicine, 69, pp. 83-85. (doi: 10.1093/occmed/kqy127)

Taylor-Rowan, M., Momoh, O., Ayerbe, L., Evans, J. J., Stott, D. J., Quinn, T. J. (2019) Prevalence of pre-stroke depression and its association with post-stroke depression: a systematic review and meta-analysis. Psychological Medicine, 49, pp. 685-696. (doi: 10.1017/S0033291718002003)

Quinn, T. J., McCleery, J., Flicker, L., Richard, E. (2019) When is Alzheimer’s not dementia—Cochrane commentary on The National Institute on Ageing and Alzheimer’s Association Research Framework for Alzheimer’s Disease. Age and Ageing, 48, pp. 174-177. (doi: 10.1093/ageing/afy167)

Burton, J. K., Lynch, E., Love, S., Rintoul, J., Starr, J. M., Shenkin, S. D. (2019) Who lives in Scotland’s care homes? Descriptive analysis using routinely collected social care data 2012–16. Journal of the Royal College of Physicians of Edinburgh, 49, pp. 12-22. (doi: 10.4997/JRCPE.2019.103)

Drozdowska, B. A., Celis-Morales, C. A., Lyall, D. M., Quinn, T. J. (2019) Social engagement after stroke – is it relevant to cognitive function? A cross-sectional analysis of UK Biobank data. AMRC Open Research, 1, (doi: 10.12688/amrcopenres.12862.2)

Arroja, M.M.C., Reid, E., Roy, L.A., Vallatos, A.V., Holmes, W.M., Nicklin, S.A., Work, L.M., McCabe, C. (2019) Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion. Scientific Reports, 9, (doi: 10.1038/s41598-019-39102-8)

Jones, F. E., Murray, L. S., McNeilly, S., Dean, A., Aman, A., Lu, Y., Nikolova, N., Malomgre, R., Horsburgh, K., Holmes, W. M., Kadler, K. E., Van Agtmael, T. (2019) 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics, 28, pp. 628-638. (doi: 10.1093/hmg/ddy369)

Abdul-Rahim, A. H., Dickie, D. A., Selvarajah, J. R., Lees, K. R., Quinn, T. J. (2019) Stroke aetiological classification reliability and effect on trial sample size: systematic review, meta-analysis and statistical modelling. Trials, 20, (doi: 10.1186/s13063-019-3222-x)

Hall, J.L., Owen, L., Riddell, A., Church, D.B., Brodbelt, D.C., O'Neill, D.G. (2019) Urinary incontinence in male dogs under primary veterinary care in England: prevalence and risk factors. Journal of Small Animal Practice, 60, pp. 86-95. (doi: 10.1111/jsap.12951)

Quinn, T. J., Mooijaart, S. P., Gallacher, K., Burton, J. K. (2019) Acute care assessment of older adults living with frailty. British Medical Journal, 364, (doi: 10.1136/bmj.l13)

Hapca, S., Burton, J. K., Cvoro, V., Reynish, E., Donnan, P. T. (2019) Are antidementia drugs associated with reduced mortality after a hospital emergency admission in the population with dementia aged 65 years and older? Alzheimer's and Dementia: Translational Research and Clinical Interventions, 5, pp. 431-440. (doi: 10.1016/j.trci.2019.07.011)

Liu, H., Lindley, R., Alim, M., Felix, C., Gandhi, D. B.C., Verma, S. J., Tugnawat, D. K., Syrigapu, A., Ramamurthy, R. K., Pandian, J. D., Walker, M., Forster, A., Hackett, M. L., Anderson, C. S., Langhorne, P., Murthy, G. V.S., Maulik, P. K., Harvey, L. A., Jan, S. (2019) Family-led rehabilitation in India (ATTEND): findings from the process evaluation of a randomized controlled trial. International Journal of Stroke, 14, pp. 53-60. (doi: 10.1177/1747493018790076)

Mazlan-Kepli, W., Dawson, J., Berry, C., Walters, M. (2019) Cessation of dual antiplatelet therapy and cardiovascular events following acute coronary syndrome. Heart, 105, pp. 67-74. (doi: 10.1136/heartjnl-2018-313148)

Burton, J. K., Marwick, C. A., Galloway, J., Hall, C., Nind, T., Reynish, E. L., Guthrie, B. (2019) Identifying care-home residents in routine healthcare datasets: a diagnostic test accuracy study of five methods. Age and Ageing, 48, pp. 114-121. (doi: 10.1093/ageing/afy137)

Findlay, M. D., Dawson, J., Dickie, D. A., Forbes, K. P., McGlynn, D., Quinn, T., Mark, P. B. (2019) Investigating the relationship between cerebral blood flow and cognitive function in hemodialysis patients. Journal of the American Society of Nephrology, 30, pp. 147-158. (doi: 10.1681/ASN.2018050462)

MacKenzie, S. M., Nguyen Dinh Cat, A., van Kralingen, J., Davies, E. (2019) Aldosterone. Springer

Quinn, T. J., Lane, D. A. (2019) Anticoagulation for atrial fibrillation in older adults—using big data for big questions. Thrombosis and Haemostasis, 119, pp. 855-857. (doi: 10.1055/s-0039-1688482)

Quinn, T. J., Makin, S., Doubal, F., Staals, J. (2019) Cerebral small vessel disease and vascular cognitive impairment. Springer

Henderson, D., Burton, J. K., Lynch, E., Clark, D., Rintoul, J., Bailey, N. (2019) Data resource profile: the Scottish Social Care Survey (SCS) and the Scottish Care Home Census (SCHC) International Journal of Population Data Science, 4, (doi: 10.23889/ijpds.v4i1.1108)

Burton, J. K., Quinn, T. J., Fisher, M. (2019) Diabetes and stroke. Practical Diabetes, 36, pp. 126-131. (doi: 10.1002/pdi.2230)

MacKenzie, S. M., Van Kralingen, J. C., Davies, E. (2019) Regulation of aldosterone secretion. Elsevier

McFall, A., Dawson, J., Work, L. M. (2019) Stroke. Springer

Findlay, M., Macisaac, R., MacLeod, M. J., Metcalfe, W., Sood, M. M., Traynor, J. P., Dawson, J., Mark, P. B. (2019) The association of atrial fibrillation and ischaemic stroke in patients on haemodialysis: a competing risk analysis. Canadian Journal of Kidney Health and Disease, 6, pp. 1-13. (doi: 10.1177/2054358119878719)

Taylor-Rowan, M., Cuthbertson, G., Keir, R., Shaw, R., Drozdowska, B., Elliott, E., Stott, D., Quinn, T. J. (2019) The prevalence of frailty amongst acute stroke patients, and evaluation of method of assessment. Clinical Rehabilitation, 33, pp. 1688-1696. (doi: 10.1177/0269215519841417)

Graham, D. (2019) Vascular physiology. Springer

2018

Burton, J. K., Guthrie, B., Hapca, S. M., Cvoro, V., Donnan, P. T., Reynish, E. L. (2018) Living at home after emergency hospital admission: prospective cohort study in older adults with and without cognitive spectrum disorder. BMC Medicine, 16, (doi: 10.1186/s12916-018-1199-z)

Munn, D., Abdul-Rahim, A., Fischer, U., Werring, D. J., Robinson, T. G., Dawson, J. (2018) A survey of opinion: When to start oral anticoagulants in patients with acute ischaemic stroke and atrial fibrillation? European Stroke Journal, 3, pp. 355-360. (doi: 10.1177/2396987318787124)

Lyons, M., Smith, C., Boaden, E., Brady, M. C., Brocklehurst, P., Dickinson, H., Hamdy, S., Higham, S., Langhorne, P., Lightbody, C., McCracken, G., Medina-Lara, A., Sproson, L., Walls, A., Watkins, D. C. (2018) Oral care after stroke: Where are we now? European Stroke Journal, 3, pp. 347-354. (doi: 10.1177/2396987318775206)

Kimberley, T. J., Pierce, D., Prudente, C. N., Francisco, G. E., Yozbatiran, N., Smith, P., Tarver, B., Engineer, N. D., Dickie, D. A., Kline, D. K., Wigginton, J. G., Cramer, S. C., Dawson, J. (2018) Vagus nerve stimulation paired with upper limb rehabilitation after chronic stroke. Stroke, 49, pp. 2789-2792. (doi: 10.1161/strokeaha.118.022279)

Graham, L. A., Aman, A., Campbell, D. D., Augley, J., Graham, D., McBride, M. W., Fraser, N. J., Ferreri, N. R., Dominiczak, A. F., Padmanabhan, S. (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50, pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018)

Hietamies, T. M., Ostrowski, C., Pei, Z., Feng, L., McCabe, C., Work, L. M., Quinn, T. J. (2018) Variability of functional outcome measures used in animal models of stroke and vascular cognitive impairment – a review of contemporary studies. Journal of Cerebral Blood Flow and Metabolism, 38, pp. 1872-1884. (doi: 10.1177/0271678X18799858)

Langhorne, P., Collier, J. M., Bate, P. J., Thuy, M. N.T., Bernhardt, J. (2018) Very early versus delayed mobilisation after stroke. Cochrane Database of Systematic Reviews, 10, (doi: 10.1002/14651858.CD006187.pub3)

Feller, M., Snel, M., Moutzouri, E., Bauer, D. C., de Montmollin, M., Aujesky, D., Ford, I., Gussekloo, J., Kearney, P. M., Mooijaart, S., Quinn, T., Stott, D., Westendorp, R., Rodondi, N., Dekkers, O. M. (2018) Association of thyroid hormone therapy with quality of life and thyroid-related symptoms in patients with subclinical hypothyroidism: a systematic review and meta-analysis. JAMA: Journal of the American Medical Association, 320, pp. 1349-1359. (doi: 10.1001/jama.2018.13770)

Urimubenshi, G., Langhorne, P., O'Donnell, M.J., Chin, S.L., Yusuf, Y., INTERSTROKE Collaborators, T. (2018) Association Between Key Performance Indicators and Patient Outcomes in Low and Middle-Income Countries in the INTERSTROKE Study. (doi: 10.1177/1747493018802481)

Bosch, J., Langhorne, P., O'Donnell, M., Urimubenshi, G., Katsoulis, L., Pandian, J., Kaddumukasa, M., DePaul, V., Carroll, S., Perera, K., Hamilton, L., Bidulka, P. (2018) Can Key Elements of a Stroke Unit be Implemented in Resource Scarce Settings? Where do we Start (the OSCAIL study) (doi: 10.1177/1747493018789543)

Katsoulis, L., Bosch, J., Langhorne, P., van Zyl, D., Hiesgen, J., Human, S., Urimubenshi, G., Hamilton, L., Bidulka, P. (2018) Characterization of Strokes Admitted to Kalafong Hospital, Pretoria, South Africa During the Baseline Phase of the OSCAIl Study. (doi: 10.1177/1747493018789543)

Katsoulis, L., Urimubenshi, G., Langhorne, P., Bosch, J., van Zyl, D., Hiesgen, J., Human, S., Hamilton, L., Bidulka, P., O'Donnell, M. (2018) Data from the OSCAIL Study on Time from Stroke Onset to Presentation at 3 Public African Hospitals: Two in Rwanda and One in South Africa. (doi: 10.1177/1747493018789543)

Morinello, C., Bewick, M., Koch, N., Bosch, J., Langhorne, P., Urimubenshi, G., Katsoulis, L., DePaul, V., Carroll, S., Hamilton, L. (2018) Developing Rehabilitation Specific Training for Organized Stroke Care in Low and Middle-Income Countries: What is Needed and How to Implement. (doi: 10.1177/1747493018789543)

DePaul, V., Urimubenshi, G., Bosch, J., Langhorne, P., Katsoulis, L., O'Donnell, M., Pandian, J., Hamilton, L., Bidulka, P., Carroll, S., Kaddumukasa, M., Perera, K. (2018) Mobility-Related Care After Stroke in the Rwandan and South African Context: Identifying Opportunities for Improvement Through the Organized Stroke Care Across Income Levels (OSCAIL) Study. (doi: 10.1177/1747493018789543)

Urimubenshi, G., Cadilhac, D. A., Kagwiza, J. N., Wu, O., Langhorne, P. (2018) Stroke care in Africa: a systematic review of the literature. International Journal of Stroke, 13, pp. 797-805. (doi: 10.1177/1747493018772747)

Hamilton, L., Bosch, J., Bidulka, P., Langhorne, P., DePaul, V., Katsoulis, L., Urimubenshi, G., Dieudonné, D., Munyantore, J., Human, S., Pandian, J., O'Donnell, M. (2018) The Effect of Loss to Follow-up on Estimating Post-Stroke Function and Mortality in Low and Middle-Income Countries: Lessons from the OSCAIL Study. (doi: 10.1177/1747493018789543)

Bidulka, P., Bosch, J., Hamilton, L., DePaul, V., Urimubenshi, G., Katsoulis, L., Langhorne, P., O'Donnell, M., Pandian, J. (2018) The OSCAIL Study: Monitoring Acute Stroke Care Services in Rwanda and South Africa. (doi: 10.1177/1747493018789543)

Miranda, F., Arevalo-Rodriguez, I., Díaz, G., Gonzalez, F., Plana, M. N., Zamora, J., Quinn, T. J., Seron, P. (2018) Confusion Assessment Method for the intensive care unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings. Cochrane Database of Systematic Reviews, 9, (doi: 10.1002/14651858.cd013126)

Findlay, M., MacIsaac, R., MacLeod, M. J., Metcalfe, W., Traynor, J. P., Dawson, J., Mark, P. B. (2018) Renal replacement modality and stroke risk in end-stage renal disease—a national registry study. Nephrology Dialysis Transplantation, 33, pp. 1564-1571. (doi: 10.1093/ndt/gfx291)

Cumming, T. B., Bernhardt, J., Lowe, D., Collier, J., Dewey, H., Langhorne, P., Thrift, A. G., Green, A., Mohanraj, R., Kramer, S. F., Churilov, L., Linden, T. (2018) Early mobilization after stroke is not associated with cognitive outcome: findings from AVERT. Stroke, 49, pp. 2147-2154. (doi: 10.1161/STROKEAHA.118.022217)

Debette, S. et al. (2018) Fourth European stroke science workshop. European Stroke Journal, 3, pp. 206-219. (doi: 10.1177/2396987318774443)

Findlay, M. D., Dawson, J., MacIsaac, R., Jardine, A. G., MacLeod, M. J., Metcalfe, W., Traynor, J. P., Mark, P. B. (2018) Inequality in care and differences in outcome following stroke in people with end stage renal disease: results from a national registry linkage analysis. Kidney International Reports, 3, pp. 1064-1076. (doi: 10.1016/j.ekir.2018.04.011)

Rhynas, S. J., Garrido, A. G., Burton, J. K., Logan, G., MacArthur, J. (2018) New care home admission following hospitalisation: How do older people, families and professionals make decisions about discharge destination? A case study narrative analysis. International Journal of Older People Nursing, 13, pp. e12192. (doi: 10.1111/opn.12192)

Divorty, N., Milligan, G., Graham, D., Nicklin, S. A. (2018) The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice. American Journal of Hypertension, 31, pp. 1049-1058. (doi: 10.1093/ajh/hpy073)

Dawson, J., Broomfield, N., Dani, K., Dickie, D. A., Doney, A., Forbes, K., Houston, G., Kean, S., Lees, K., McConnachie, A., Muir, K. W., Quinn, T., Struthers, A., Walters, M. (2018) Xanthine oxidase inhibition for the improvement of long-term outcomes following ischaemic stroke and transient ischaemic attack (XILO-FIST) – Protocol for a randomised double blind placebo-controlled clinical trial. European Stroke Journal, 3, pp. 281-290. (doi: 10.1177/2396987318771426)

Jones, K. M. et al. (2018) Determining the feasibility and preliminary efficacy of a stroke instructional and educational DVD in a multinational context: a randomized controlled pilot study. Clinical Rehabilitation, 32, pp. 1086-1097. (doi: 10.1177/0269215518777565)

Wilkinson, T., Ly, A., Schnier, C., Rannikmäe, K., Bush, K., Brayne, C., Quinn, T. J., Sudlow, C. L.M. (2018) Identifying dementia cases with routinely-collected health data: a systematic review. Alzheimer's and Dementia, 14, pp. 1038-1051. (doi: 10.1016/j.jalz.2018.02.016)

Rajani, R. M., Quick, S., Ruigrok, S. R., Graham, D., Harris, S. E., Verhaaren, B. F.J., Fornage, M., Seshadri, S., Atanur, S. S., Dominiczak, A. F., Smith, C., Wardlaw, J. M., Williams, A. (2018) Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats. Science Translational Medicine, 10, (doi: 10.1126/scitranslmed.aam9507)

Kishore, A. K., Vail, A., Jeans, A. R., Chamorro, A., Di Napoli, M., Kalra, L., Langhorne, P., Roffe, C., Westendorp, W., Nederkoorn, P. J., Garau, J., van de Beek, D., Montaner, J., Woodhead, M., Meisel, A., Smith, C. J. (2018) Microbiological etiologies of pneumonia complicating stroke: a systematic review. Stroke, 49, pp. 1602-1609. (doi: 10.1161/STROKEAHA.117.020250)

Morgan, H. L., Butler, E., Ritchie, S., Herse, F., Dechend, R., Beattie, E., McBride, M. W., Graham, D. (2018) Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats. Hypertension, 72, pp. 208-218. (doi: 10.1161/HYPERTENSIONAHA.118.10935)

Owen, R. K., Cooper, N. J., Quinn, T. J., Lees, R., Sutton, A. J. (2018) Network meta-analysis of diagnostic test accuracy studies identifies and ranks the optimal diagnostic tests and thresholds for healthcare policy and decision making. Journal of Clinical Epidemiology, 99, pp. 64-74. (doi: 10.1016/j.jclinepi.2018.03.005)

Baylan, S., McGinlay, M., MacDonald, M., Easto, J., Cullen, B., Haig, C., Mercer, S. W., Murray, H., Quinn, T. J., Stott, D., Broomfield, N. M., Stiles, C., Evans, J. J. (2018) Participants’ experiences of music, mindful music, and audiobook listening interventions for people recovering from stroke. Annals of the New York Academy of Sciences, 1423, pp. 349-359. (doi: 10.1111/nyas.13618)

Burton, J. K., Papworth, R., Haig, C., McCowan, C., Ford, I., Stott, D. J., Quinn, T. J. (2018) Statin use is not associated with future long-term care admission - extended follow-up of two randomised controlled trials. Drugs and Aging, 35, pp. 657-663. (doi: 10.1007/s40266-018-0560-4)

De Lucca Camargo, L., Harvey, A. P., Rios, F. J., Tsiropoulou, S., Silva, R. D. N. d. O., Cao, Z., Graham, D., McMaster, C., Burchmore, R. J., Hartley, R. C., Bulleid, N., Montezano, A. C., Touyz, R. M. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72, pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824)

Bailey, E., McBride, M. W., McClure, J. D., Beattie, W., Graham, D., Dominiczak, A., Smith, C., Wardlaw, J. (2018) Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease. Clinical Science, 132, pp. 1315-1328. (doi: 10.1042/CS20171572)

Montezano, A. C., De Lucca Camargo, L., Persson, P., Rios, F. J., Harvey, A. P., Agnostopoulou, A., Palacios, R., Gandara, A. C. P., Alves-Lopes, R., Neves, K. B., Dulak-Lis, M., Holterman, C. E., Lagerblad de Oliveira, P., Graham, D., Kennedy, C., Touyz, R. M. (2018) NADPH oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.009388)

Montezano, A. C., De Lucca Camargo, L., Persson, P., Rios, F., Harvey, A., Anagnostopoulou, A., Palacios, R., Gandara, A. C. P., Alves‐Lopes, R., Neves, K., Dulak‐Lis, M., Holterman, C. E., de Oliveira, P. L., Graham, D., Kennedy, C., Touyz, R. (2018) NADPH Oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.009388)

Langhorne, P. et al. (2018) Practice patterns and outcomes after stroke across countries at different economic levels (INTERSTROKE): an international observational study. Lancet, 391, pp. 2019-2027. (doi: 10.1016/S0140-6736(18)30802-X)

Burton, J. K., Guthrie, B. (2018) Identifying who lives in a care home—a challenge to be conquered. Age and Ageing, 47, pp. 322-323. (doi: 10.1093/ageing/afx200)

Takwoingi, Y., Quinn, T. (2018) Review of Diagnostic Test Accuracy (DTA) studies in older people. Age and Ageing, 47, pp. 349-355. (doi: 10.1093/ageing/afy023)

Yogendrakumar, V., Smith, E. E., Demchuk, A. M., Aviv, R. I., Rodriguez-Luna, D., Molina, C. A., Silva Blas, Y., Dzialowski, I., Kobayashi, A., Boulanger, J.-M., Lum, C., Gubitz, G., Padma, V., Roy, J., Kase, C. S., Bhatia, R., Ali, M., Lyden, P., Hill, M. D., Dowlatshahi, D. (2018) Lack of early improvement predicts poor outcome following acute intracerebral hemorrhage. Critical Care Medicine, 46, pp. e310-e317. (doi: 10.1097/CCM.0000000000002962)

Horsburgh, K. et al. (2018) Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology. Clinical Science, 132, pp. 851-868. (doi: 10.1042/CS20171620)

Quinn, T. J., Livingstone, I., Weir, A., Shaw, R., Breckenridge, A., McAlpine, C., Tarbert, C. M. (2018) Accuracy and feasibility of an android-based digital assessment tool for post stroke visual disorders - The StrokeVision App. Frontiers in Neurology, 9, (doi: 10.3389/fneur.2018.00146)

Taylor-Rowan, M., Wilson, A., Dawson, J., Quinn, T. J. (2018) Functional assessment for acute stroke trials: properties, analysis, and application. Frontiers in Neurology, 9, (doi: 10.3389/fneur.2018.00191)

Kilgard, M. P., Rennaker, R. L., Alexander, J., Dawson, J. (2018) Vagus nerve stimulation paired with tactile training improved sensory function in a chronic stroke patient. NeuroRehabilitation, 42, pp. 159-165. (doi: 10.3233/nre-172273)

Weir, C. J., Butcher, I., Assi, V., Lewis, S. C., Murray, G. D., Langhorne, P., Brady, M. C. (2018) Dealing with missing standard deviation and mean values in meta-analysis of continuous outcomes: a systematic review. BMC Medical Research Methodology, 18, (doi: 10.1186/s12874-018-0483-0)

Al-Shahi Salman, R. et al. (2018) The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial. Trials, 19, (doi: 10.1186/s13063-018-2542-6)

Bath, P. M. et al. (2018) Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial. Lancet, 391, pp. 850-859. (doi: 10.1016/S0140-6736(17)32849-0)

Mackinnon, S., Drozdowska, B. A., Hamilton, M., Noel-Storr, A. H., McShane, R., Quinn, T. (2018) Are methodological quality and completeness of reporting associated with citation-based measures of publication impact? A secondary analysis of a systematic review of dementia biomarker studies. BMJ Open, 8, (doi: 10.1136/bmjopen-2017-020331)

Ward, E., Gillies, J., Armstrong, D., Grant, L., Elder, A., Burton, J., Ryan, C., Quinn, C. (2018) Cultivating compassionate care: why does it matter and what can we do to promote it? Journal of the Royal College of Physicians of Edinburgh, 48, pp. 71-77. (doi: 10.4997/jrcpe.2018.117)

Skrobot, O. A. et al. (2018) Progress toward standardized diagnosis of vascular cognitive impairment: guidelines from the Vascular Impairment of Cognition Classification Consensus Study. Alzheimer's and Dementia, 14, pp. 280-292. (doi: 10.1016/j.jalz.2017.09.007)

Makin, S. D.J., Doubal, F. N., Quinn, T. J., Bath, P. M.W., Dennis, M. S., Wardlaw, J. M. (2018) The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke. European Stroke Journal, 3, pp. 66-73. (doi: 10.1177/2396987317728854)

Quinn, T. J., Elliott, E., Langhorne, P. (2018) Cognitive and mood assessment tools for use in stroke. Stroke, 49, pp. 483-490. (doi: 10.1161/STROKEAHA.117.016994)

Askim, T. et al. (2018) Efficacy and safety of individualized coaching after stroke: the LAST Study (Life After Stroke): a pragmatic randomized controlled trial. Stroke, 49, pp. 426-432. (doi: 10.1161/STROKEAHA.117.018827)

Gallacher, K., Quinn, T. J. (2018) The LAST word on coaching as a stroke intervention? Stroke, 49, pp. 279-280. (doi: 10.1161/STROKEAHA.117.020001)

Gallacher, K. L., May, C. R., Langhorne, P., Mair, F. S. (2018) A conceptual model of treatment burden and patient capacity in stroke. BMC Family Practice, 19, (doi: 10.1186/s12875-017-0691-4)

van der Wardt, V., Burton, J. K., Conroy, S., Welsh, T., Logan, P., Taggar, J., Tanajewski, L., Gladman, J. (2018) Withdrawal of antihypertensive therapy in people with dementia: feasibility study. Pilot and Feasibility Studies, 4, (doi: 10.1186/s40814-017-0221-0)

McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)

Arba, F., Quinn, T. J., Hankey, G. J., Lees, K. R., Wardlaw, J. M., Ali, M., Inzitari, D. (2018) Enlarged perivascular spaces and cognitive impairment after stroke and transient ischemic attack. International Journal of Stroke, 13, pp. 47-56. (doi: 10.1177/1747493016666091)

Burton, J. K., Ferguson, E. E.C., Barugh, A. J., Walesby, K. E., MacLullich, A. M.J., Shenkin, S. D., Quinn, T. J. (2018) Predicting discharge to institutional long-term care after stroke: a systematic review and metaanalysis. Journal of the American Geriatrics Society, 66, pp. 161-169. (doi: 10.1111/jgs.15101)

Quinn, T. J. (2018) Stroke literature synopses: clinical science. Stroke, 49, pp. e5-e6. (doi: 10.1161/STROKEAHA.117.019655)

Taylor-Rowan, M. et al. (2018) Assessing the psychometric properties of the his "Think Frailty" tool. Age and Ageing, 47, pp. iii20-iii23. (doi: 10.1093/ageing/afy127.02)

Ioannou, A., Carin-Levy, G., Cheyne, J. D., Clarke, D., Cowey, E., Fallon, M., Morton, S., Klinkhamer, L., Kyriakou, G., Fleetwood-Walker, S., Quinn, T., Rush, R., Sande, T., Smith, M., Whalley-Sibley, H., Woodfield, R., Mead, G. (2018) Incidence, types and nature of post-stroke pain: systematic review of literature and meta-analysis [Protocol]

Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)

2017

Todd, A., Blackley, S., Burton, J. K., Stott, D. J., Ely, E. W., Tieges, Z., MacLullich, A. M.J., Shenkin, S. D. (2017) Reduced level of arousal and increased mortality in adult acute medical admissions: a systematic review and meta-analysis. BMC Geriatrics, 17, (doi: 10.1186/s12877-017-0661-7)

Urimubenshi, G., Langhorne, P., Cadilhac, D. A., Kagwiza, J. N., Wu, O. (2017) Association between patient outcomes and key performance indicators of stroke care quality: A systematic review and meta-analysis. European Stroke Journal, 2, pp. 287-307. (doi: 10.1177/2396987317735426)

O'Neill, D.G., Riddell, A., Church, D.B., Owen, L., Brodbelt, D.C., Hall, J.L. (2017) Urinary incontinence in bitches under primary veterinary care in England: prevalence and risk factors. Journal of Small Animal Practice, 58, pp. 685-693. (doi: 10.1111/jsap.12731)

Shepperd, S., Cradduck-Bamford, A., Butler, C., Ellis, G., Godfrey, M., Gray, A., Hemsley, A., Khanna, P., Langhorne, P., McCaffrey, P., Mirza, L., Pushpangadan, M., Ramsay, S., Schiff, R., Stott, D., Young, J., Yu, L.-M. (2017) A multi-centre randomised trial to compare the effectiveness of geriatrician-led admission avoidance hospital at home versus inpatient admission. Trials, 18, (doi: 10.1186/s13063-017-2214-y)

Oldroyd, C., Scholz, A. F.M., Hinchcliffe, R. J., McCarthy, K., Hewitt, J., Quinn, T. J. (2017) A systematic review and meta-analysis of factors for delirium in vascular surgical patients. Journal of Vascular Surgery, 66, pp. 1269-1279.e9. (doi: 10.1016/j.jvs.2017.04.077)

Dawson, J., Wyss, A. (2017) Chicken or the egg? Hyperuricemia, insulin resistance, and hypertension. Hypertension, 70, pp. 698-699. (doi: 10.1161/HYPERTENSIONAHA.117.09685)

Lees, R. A., Hendry, K., Broomfield, N., Stott, D., Larner, A. J., Quinn, T. (2017) Cognitive assessment in stroke: feasibility and test properties using differing approaches to scoring of incomplete items. International Journal of Geriatric Psychiatry, 32, pp. 1072-1078. (doi: 10.1002/gps.4568)

Quinn, T. (2017) Review: Real-world use of nonsteroidal antiinflammatory drugs is associated with acute myocardial infarction. Annals of Internal Medicine, 167, (doi: 10.7326/acpjc-2017-167-6-030)

Ellis, G., Gardner, M., Tsiachristas, A., Langhorne, P., Burke, O., Harwood, R. H., Conroy, S. P., Kircher, T., Somme, D., Saltvedt, I., Wald, H., O'Neill, D., Robinson, D., Shepperd, S. (2017) Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database of Systematic Reviews, 2017, (doi: 10.1002/14651858.cd006211.pub3)

Quinn, T. J., Singh, S., Lees, K. R., Bath, P. M., Myint, P. K. (2017) Validating and comparing stroke prognosis scales. Neurology, 89, pp. 997-1002. (doi: 10.1212/WNL.0000000000004332)

Langhorne, P., Wu, O., Rodgers, H., Ashburn, A., Bernhardt, J. (2017) A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial. Health Technology Assessment, 21, pp. 1-120. (doi: 10.3310/hta21540)

Mazlan-Kepli, W., MacIsaac, R. L., Walters, M., Bath, P. M. W., Dawson, J. (2017) Interruption to antiplatelet therapy early after acute ischaemic stroke: A nested case-control study. British Journal of Clinical Pharmacology, 83, pp. 2045-2055. (doi: 10.1111/bcp.13290)

Thorén, M., Azevedo, E., Dawson, J., Egido, J. A., Falcou, A., Ford, G. A., Holmin, S., Mikulik, R., Ollikainen, J., Wahlgren, N., Ahmed, N. (2017) Predictors for cerebral edema in acute ischemic stroke treated with intravenous thrombolysis. Stroke, 48, pp. 2464-2471. (doi: 10.1161/STROKEAHA.117.018223)

Quinn, T. J. (2017) Stroke literature synopses: clinical science. Stroke, 48, pp. e243-e244. (doi: 10.1161/STROKEAHA.117.018510)

van der Wardt, V., Harrison, J. K., Welsh, T., Conroy, S., Gladman, J. (2017) Withdrawal of antihypertensive medication: a systematic review. Journal of Hypertension, 35, pp. 1742-1749. (doi: 10.1097/HJH.0000000000001405)

Lindley, R. I. et al. (2017) Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial. Lancet, 390, pp. 588-599. (doi: 10.1016/S0140-6736(17)31447-2)

Robertson, S., Diver, L. A., Alvarez-Madrazo, S., Livie, C., Ejaz, A., Fraser, R., Connell, J. M., MacKenzie, S. M., Davies, E. (2017) Regulation of corticosteroidogenic genes by microRNAs. International Journal of Endocrinology, 2017, (doi: 10.1155/2017/2021903)

Rodgers, H. et al. (2017) Robot Assisted Training for the Upper Limb after Stroke (RATULS): study protocol for a randomised controlled trial. Trials, 18, (doi: 10.1186/s13063-017-2083-4)

Legg, L. A., Lewis, S. R., Schofield-Robinson, O. J., Drummond, A., Langhorne, P. (2017) Occupational therapy for adults with problems in activities of daily living after stroke. Cochrane Database of Systematic Reviews, 2017, (doi: 10.1002/14651858.CD003585.pub3)

Langhorne, P., Baylan, S. (2017) Early supported discharge services for people with acute stroke. Cochrane Database of Systematic Reviews, 2017, (doi: 10.1002/14651858.CD000443.pub4)

Wehling, M., Collins, R., Gil, V. M., Hanon, O., Hardt, R., Hoffmeister, M., Monteiro, P., Quinn, T. J., Ropers, D., Sergi, G., Verheugt, F. W.A. (2017) Appropriateness of oral anticoagulants for long-term treatment of atrial fibrillation in older people: results of an evidence-based review and international consensus validation process (OAC-FORTA 2016) Drugs and Aging, 34, pp. 499-507. (doi: 10.1007/s40266-017-0466-6)

Walker, M. F., Hoffmann, T. C., Brady, M. C., Dean, C. M., Eng, J. J., Farrin, A. J., Felix, C., Forster, A., Langhorne, P., Lynch, E. A., Radford, K. A., Sunnerhagen, K. S., Watkins, C. L. (2017) Improving the development, monitoring and reporting of stroke rehabilitation research: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke, 12, pp. 472-479. (doi: 10.1177/1747493017711815)

Harrison, J. K., Walesby, K. E., Hamilton, L., Armstrong, C., Starr, J. M., Reynish, E. L., MacLullich, A. M.J., Quinn, T., Shenkin, S. D. (2017) Predicting discharge to institutional long-term care following acute hospitalisation: a systematic review and meta-analysis. Age and Ageing, 46, pp. 547-558. (doi: 10.1093/ageing/afx047)

Arba, F., Inzitari, D., Ali, M., Warach, S.J., Luby, M., Lees, K.R. (2017) Small vessel disease and clinical outcomes after IV rt-PA treatment. Acta Neurologica Scandinavica, 136, pp. 72-77. (doi: 10.1111/ane.12745)

Kwakkel, G., Lannin, N. A., Borschmann, K., English, C., Ali, M., Churilov, L., Saposnik, G., Winstein, C., van Wegen, E. E., Wolf, S. L., Krakauer, J. W., Bernhardt, J. (2017) Standardized measurement of sensorimotor recovery in stroke trials: consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable. International Journal of Stroke, 12, pp. 451-461. (doi: 10.1177/1747493017711813)

Wang, D., Mohammad, M., Wang, Y., Tan, R., Murray, L. S., Ricardo, S., Dagher, H., van Agtmael, T., Savige, J. (2017) The chemical chaperone, PBA, reduces ER stress and autophagy and increases collagen IV α5 expression in cultured fibroblasts from men with X-linked Alport syndrome and missense mutations. Kidney International Reports, 2, pp. 739-748. (doi: 10.1016/j.ekir.2017.03.004)

Gonçalves-Bradley, D. C., Iliffe, S., Doll, H. A., Broad, J., Gladman, J., Langhorne, P., Richards, S. H., Shepperd, S., Shepperd, S. (2017) Early discharge hospital at home. Cochrane Database of Systematic Reviews, 2017, (doi: 10.1002/14651858.CD000356.pub4)

Shenkin, S. D., Harrison, J. K., Wilkinson, T., Dodds, R. M., Ioannidis, J. P. A. (2017) Systematic reviews: guidance relevant for studies of older people. Age and Ageing, 46, pp. 722-728. (doi: 10.1093/ageing/afx105)

Harvey, A. P., Montezano, A. C., Hood, K. Y., Lopes, R. A., Rios, F., Ceravolo, G., Graham, D., Touyz, R. M. (2017) Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis. Life Sciences, 179, pp. 110-119. (doi: 10.1016/j.lfs.2017.05.002)

Quinn, T. J., Taylor-Rowan, M., Coyte, A., Clark, A. B., Musgrave, S. D., Metcalf, A. K., Day, D. J., Bachman, M. O., Warburton, E. A., Potter, J. F., Myint, P. K. (2017) Pre-stroke modified Rankin scale: evaluation of validity, prognostic accuracy and association with treatment. Frontiers in Neurology, 8, (doi: 10.3389/fneur.2017.00275)

Arba, F., Quinn, T., Hankey, G.J., Inzitari, D., Ali, M., Lees, K. R. (2017) Determinants of post-stroke cognitive impairment: analysis from VISTA. Acta Neurologica Scandinavica, 136, pp. 603-607. (doi: 10.1111/ane.12637)

Skrobot, O. A. et al. (2017) The vascular impairment of cognition classification consensus study. Alzheimer's and Dementia, 13, pp. 624-633. (doi: 10.1016/j.jalz.2016.10.007)

Stott, D. J. et al. (2017) Thyroid hormone therapy for older adults with subclinical hypothyroidism. New England Journal of Medicine, 376, pp. 2534-2544. (doi: 10.1056/NEJMoa1603825)

Walesby, K.E., Harrison, J.K., Russ, T.C. (2017) What big data could achieve in Scotland. Journal of the Royal College of Physicians of Edinburgh, 47, pp. 114-119. (doi: 10.4997/jrcpe.2017.201)

Harrison, J. K., MacArthur, J., Garrido, A. G., Logan, G., Rhynas, S. J., MacLullich, A. M.J., Shenkin, S. D. (2017) Decisions affecting discharge from hospitals directly to care homes. Nursing Times, 113, pp. 29-32.

Urimubenshi, G., Langhorne, P., Cadilhac, D. (2017) Key Performance Indicators of Quality Stroke Care and their Association With Patient Outcomes: a Systematic Literature Review. (doi: 10.1177/2396987317705242)

Harrison, J. K., Reid, J., Quinn, T. J., Shenkin, S. D. (2017) Using quality assessment tools to critically appraise ageing research: a guide for clinicians. Age and Ageing, 46, pp. 359-365. (doi: 10.1093/ageing/afw223)

Cannon, J. A., Moffitt, P., Perez-Moreno, A. C., Walters, M. R., Broomfield, N. M., McMurray, J. J.V., Quinn, T. J. (2017) Cognitive impairment and heart failure: systematic review and meta-analysis. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2017.04.007)

Doubal, F. N., Ali, M., Batty, G. D., Charidimou, A., Eriksdotter, M., Hofmann-Apitius, M., Kim, Y.-H., Levine, D. A., Mead, G., Mucke, H. A.M., Ritchie, C., Roberts, C., Russ, T. C., Stewart, R., Whiteley, W., Quinn, T. J. (2017) Big data and data repurposing - using existing data to answer new questions in vascular dementia research. BMC Neurology, 17, (doi: 10.1186/s12883-017-0841-2)

Quinn, T. J., McCleery, J. (2017) Diagnosis in vascular dementia, applying ‘Cochrane diagnosis rules’ to ‘dementia diagnostic tools’ Clinical Science, 131, pp. 729-732. (doi: 10.1042/CS20170025)

Young, C., Hall, A. M., Gonçalves-Bradley, D. C., Quinn, T. J., Hooft, L., van Munster, B. C., Stott, D. J. (2017) Home or foster home care versus institutional long-term care for functionally dependent older people. Cochrane Database of Systematic Reviews, 2017, (doi: 10.1002/14651858.CD009844.pub2)

Dawson, J., Mark, P. B. (2017) Uric acid and decline in renal function-partners in crime. American Journal of Nephrology, 45, pp. 327-329. (doi: 10.1159/000464261)

MacKenzie, S. M., Freel, M., Connell, J. M., Fraser, R., Davies, E. (2017) ACTH and polymorphisms at steroidogenic loci as determinants of aldosterone secretion and blood pressure. International Journal of Molecular Sciences, 18, (doi: 10.3390/ijms18030579)

Mazlan-Kepli, W., Macisaac, R. L., Walters, M., Bath, P. M.W., Dawson, J. (2017) Antiplatelet therapy following ischaemic stroke – continue or change pre-existing therapy? European Stroke Journal, 2, pp. 31-36. (doi: 10.1177/2396987316678728)

Hockley, J., Burton, J. K., Watson, J., Randall, M., Murray, S. (2017) Fixing the broken image of care homes, could a ‘care home innovation centre’ be the answer? Age and Ageing, 46, pp. 175-178. (doi: 10.1093/ageing/afw154)

Ali, M., MacIsaac, R., Quinn, T. J., Bath, P. M., Veenstra, D. L., Xu, Y., Brady, M. C., Patel, A., Lees, K. R. (2017) Dependency and health utilities in stroke: Data to inform cost-effectiveness analyses. European Stroke Journal, 2, pp. 70-76. (doi: 10.1177/2396987316683780)

Small, H. Y., Akehurst, C., Sharafetdinova, L., McBride, M. W., McClure, J. D., Robinson, S. W., Carty, D. M., Freeman, D. J., Delles, C. (2017) HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia. Physiological Genomics, 49, pp. 193-200. (doi: 10.1152/physiolgenomics.00106.2016)

Harrison, J. K., Garrido, A. G., Rhynas, S. J., Logan, G., MacLullich, A. M.J., MacArthur, J., Shenkin, S. (2017) New institutionalisation following acute hospital admission: a retrospective cohort study. Age and Ageing, 46, pp. 238-244. (doi: 10.1093/ageing/afw188)

Wilson, A., Bath, P. M.W., Berge, E., Cadilhac, D. A., Cuche, M., Ford, G. A., Macisaac, R., Quinn, T. J., Taylor, M., Walters, M., Wolff, C., Lees, K. R. (2017) Understanding the relationship between costs and the modified Rankin Scale: A systematic review, multidisciplinary consensus and recommendations for future studies. European Stroke Journal, 2, pp. 3-12. (doi: 10.1177/2396987316684705)

MacIsaac, R. L., Ali, M., Taylor-Rowan, M., Rodgers, H., Lees, K. R., Quinn, T. J. (2017) Use of a 3-item short-form version of the Barthel Index for use in stroke. Stroke, 48, pp. 618-623. (doi: 10.1161/STROKEAHA.116.014789)

Horrocks, S., Wilkinson, T., Schnier, C., Ly, A., Woodfield, R., Rannikmäe, K., Quinn, T. J., Sudlow, C. L.M. (2017) Accuracy of routinely-collected healthcare data for identifying motor neurone disease cases: a systematic review. PLoS ONE, 12, (doi: 10.1371/journal.pone.0172639)

Hanley, D. F. et al. (2017) Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial. Lancet, 389, pp. 603-611. (doi: 10.1016/S0140-6736(16)32410-2)

Stott, D. J. et al. (2017) Study protocol; thyroid hormone replacement for untreated older adults with subclinical hypothyroidism - a randomised placebo controlled trial (TRUST) BMC Endocrine Disorders, 17, (doi: 10.1186/s12902-017-0156-8)

Quinn, T. J., McCleery, J., Noel-Storr, A. H., Marcus, S., Flicker, L. (2017) Cochrane dementia group turns 21—older and (slightly) wiser. Journal of the American Medical Directors Association, 18, pp. 96-98. (doi: 10.1016/j.jamda.2016.11.007)

Billot, L., Lindley, R. I., Harvey, L. A., Maulik, P. K., Hackett, M. L., Murthy, G. V., Anderson, C. S., Shamanna, B. R., Jan, S., Walker, M., Forster, A., Langhorne, P., Verma, S. J., Felix, C., Alim, M., Gandhi, D. B., Pandian, J. D. (2017) Statistical analysis plan for the family-led rehabilitation after stroke in India (ATTEND) trial: a multicenter randomized controlled trial of a new model of stroke rehabilitation compared to usual care. International Journal of Stroke, 12, pp. 208-210. (doi: 10.1177/1747493016674956)

Arba, F., Quinn, T., Hankey, G.J., Ali, M., Lees, K. R., Inzitari, D. (2017) Cerebral small vessel disease, medial temporal lobe atrophy and cognitive status in patients with ischaemic stroke and transient ischaemic attack. European Journal of Neurology, 24, pp. 276-282. (doi: 10.1111/ene.13191)

Koh-Tan, H.H. C., Dashti, M., Wang, T., Beattie, W., Mcclure, J., Young, B., Dominiczak, A. F., McBride, M. W., Graham, D. (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35, pp. 319-329. (doi: 10.1097/HJH.0000000000001155)

Santana, S., Rente, J., Neves, C., Redondo, P., Szczygiel, N., Larsen, T., Jepsen, B., Langhorne, P. (2017) Early home-supported discharge for patients with stroke in Portugal: a randomised controlled trial. Clinical Rehabilitation, 31, pp. 197-206. (doi: 10.1177/0269215515627282)

Bernhardt, J., Godeckeb, E., Johnson, L., Langhorne, P. (2017) Early rehabilitation after stroke. Current Opinion in Neurology, 30, pp. 48-54. (doi: 10.1097/WCO.0000000000000404)

Tsiropoulou, S., McBride, M., Padmanabhan, S. (2017) Urine metabolomics in hypertension research. Springer

Mijajlović, M. D. et al. (2017) Post-stroke dementia – a comprehensive review. BMC Medicine, 15, (doi: 10.1186/s12916-017-0779-7)

Mancini, S. J., White, A. D., Bijland, S., Rutherford, C., Graham, D., Richter, E. A., Viollet, B., Touyz, R. M., Palmer, T. M., Salt, I. P. (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010)

Stott J., D., Quinn, T. J. (2017) Principles of rehabilitation of older people. Medicine, 45, pp. 1-5. (doi: 10.1016/j.mpmed.2016.10.002)

Quinn, T., Shaw, R., Taylor-Rowan, M. (2017) Abstract TP439: Occurrence (Incidence and Prevalence) Rate of Delirium and Risk Factors in Acute Stroke - Cross-sectional Study. Stroke, 48, (doi: 10.1161/str.48.suppl_1.tp439)

MacKenzie, S. M., Davies, E., Alvarez-Madrazo, S. (2017) Analysis of the aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1) genes. Springer

Quinn, T. J., Takwoingi, Y. (2017) Assessment of the utility of cognitive screening instruments. Springer

Burton, J.K., Quinn, T.J., Gordon, A.L., MacLullich, A.M.J., Reynish, E.L., Shenkin, S.D. (2017) Identifying published studies of care home research: an international survey of researchers. Journal of Nursing Home Research, 3, pp. 99-102. (doi: 10.14283/jnhrs.2017.15)

Kerr, A., Dawson, J., Robertson, C., Rowe, P., Quinn, T. J. (2017) Sit to stand activity during stroke rehabilitation. Topics in Stroke Rehabilitation, 24, pp. 562-566. (doi: 10.1080/10749357.2017.1374687)

2016

METACOHORTS Consortium, et al. (2016) METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research. Alzheimer's and Dementia, 12, pp. 1235-1249. (doi: 10.1016/j.jalz.2016.06.004)

Harrison, J. K., Stott, D. J., McShane, R., Noel-Storr, A. H., Swann-Price, R. S., Quinn, T. J. (2016) Informant questionnaire on cognitive decline in the elderly (IQCODE) for the early diagnosis of dementia across a variety of healthcare settings. Cochrane Database of Systematic Reviews, 2016, (doi: 10.1002/14651858.cd011333.pub2)

Harrison, J. K., Noel-Storr, A. H., Demeyere, N., Reynish, E. L., Quinn, T. J. (2016) Outcomes measures in a decade of dementia and mild cognitive impairment trials. Alzheimer's Research and Therapy, 8, (doi: 10.1186/s13195-016-0216-8)

Verdura, E., Hervé, D., Bergametti, F., Jacquet, C., Morvan, T., Prieto-Morin, C., Mackowiak, A., Manchon, E., Hosseini, H., Cordonnier, C., Girard-Buttaz, I., Rosenstingl, S., Hagel, C., Kuhlenbaümer, G., Leca-Radu, E., Goux, D., Fleming, L., Van Agtmael, T., Chabriat, H., Chapon, F., Tournier-Lasserve, E. (2016) Disruption of a miR-29 binding site leading to COL4A1 upregulation causes pontine autosomal dominant microangiopathy with leukoencephalopathy. Annals of Neurology, 80, pp. 741-753. (doi: 10.1002/ana.24782)

Pérez, L. M., Inzitari, M., Quinn, T. J., Montaner, J., Gavaldà, R., Duarte, E., Coll-Planas, L., Cerdà, M., Santaeugenia, S., Closa, C., Gallofré, M. (2016) Rehabilitation profiles of older adult stroke survivors admitted to intermediate care units: a multi-centre study. PLoS ONE, 11, (doi: 10.1371/journal.pone.0166304)

Harrison, J. K., Van Der Wardt, V., Conroy, S. P., Stott, D. J., Dening, T., Gordon, A. L., Logan, P., Welsh, T. J., Taggar, J., Harwood, R., Gladman, J. R.F. (2016) New horizons: the management of hypertension in people with dementia. Age and Ageing, 45, pp. 740-746. (doi: 10.1093/ageing/afw155)

Moffitt, P., Park, H., Lane, D. A., O'Connell, J., Quinn, T. J. (2016) Thromboprophylaxis in atrial fibrillation and association with cognitive decline: systematic review. Age and Ageing, 45, pp. 767-775. (doi: 10.1093/ageing/afw104)

Jongstra, S., Harrison, J. K., Quinn, T. J., Richard, E. (2016) Antihypertensive withdrawal for the prevention of cognitive decline. Cochrane Database of Systematic Reviews, 2016, (doi: 10.1002/14651858.cd011971.pub2)

Baylan, S., Swann-Price, R., Peryer, G., Quinn, T. (2016) The effects of music listening interventions on cognition and mood post-stroke: a systematic review. Expert Review of Neurotherapeutics, 16, pp. 1241-1249. (doi: 10.1080/14737175.2016.1227241)

Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D., Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68, pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933)

Siddiqi, N., Cheater, F., Collinson, M., Farrin, A., Forster, A., George, D., Godfrey, M., Graham, E., Harrison, J., Heaven, A., Heudtlass, P., Hulme, C., Meads, D., North, C., Sturrock, A., Young, J. (2016) The PiTSTOP study: a feasibility cluster randomized trial of delirium prevention in care homes for older people. Age and Ageing, 45, pp. 651-660. (doi: 10.1093/ageing/afw091)

Liu, H., Lindley, R., Alim, M., Felix, C., Gandhi, D. B.C., Verma, S. J., Tugnawat, D. K., Syrigapu, A., Ramamurthy, R. K., Pandian, J. D., Walker, M., Forster, A., Anderson, C. S., Langhorne, P., Murthy, G. V. S., Shamanna, B. R., Hackett, M. L., Maulik, P. K., Harvey, L. A., Jan, S. (2016) Protocol for process evaluation of a randomised controlled trial of family-led rehabilitation post stroke (ATTEND) in India. BMJ Open, 6, (doi: 10.1136/bmjopen-2016-012027)

Wilson, M. R., Parakramawansha, R., Quinn, T. J., Tait, R. C. (2016) Quality and predictors of anticoagulant control with vitamin K antagonist for stroke prevention in atrial fibrillation. Thrombosis and Haemostasis, 116, pp. 578-580. (doi: 10.1160/TH16-01-0025)

Dawson, J., McGrane, F. (2016) Vagus nerve stimulation and upper limb rehabilitation. Current Physical Medicine and Rehabilitation Reports, 4, pp. 186-189. (doi: 10.1007/s40141-016-0129-2)

Morgan, H., Small, H.Y., Beattie, E., McBride, M.W., Graham, D. (2016) [OP.5D.02] Transcriptomic changes in early pregnancy-associated uterine artery remodelling in stroke prone spontaneously hypertensive rat. Journal of Hypertension, 34, pp. e63-e63. (doi: 10.1097/01.hjh.0000491501.79443.05)

Kirkham, J. G., Takwoingi, Y., Quinn, T. J., Rapoport, M., Lanctôt, K. L., Maxwell, C. J., Herrmann, N., Gill, S. S., Rochon, P. A., Seitz, D. P. (2016) Depression rating scales for detection of major depression in people with dementia. Cochrane Database of Systematic Reviews, 2016, (doi: 10.1002/14651858.cd012312)

Findlay, M. D., Thomson, P. C., Macisaac, R., Jardine, A. G., Patel, R. K., Stevens, K. K., Rutherford, E., Clancy, M., Geddes, C. C., Dawson, J., Mark, P. B. (2016) Risk factors and outcome of stroke in renal transplant recipients. Clinical Transplantation, 30, pp. 918-924. (doi: 10.1111/ctr.12765)

Conroy, S. P., Harrison, J. K., Van Der Wardt, V., Harwood, R., Logan, P., Welsh, T., Gladman, J. R.F. (2016) Ambulatory blood pressure monitoring in older people with dementia: a systematic review of tolerability. Age and Ageing, 45, pp. 456-462. (doi: 10.1093/ageing/afw050)

Maile, E.L., Harrison, J.K., Chikura, G., Russ, K., Conroy, S.P. (2016) Ethical issues for older people in the emergency department. European Geriatric Medicine, 7, pp. 372-378. (doi: 10.1016/j.eurger.2016.02.005)

Quinn, T. (2016) Review: evidence is insufficient to determine the risk–benefit ratio for vision acuity screening in older adults. Annals of Internal Medicine, 164, (doi: 10.7326/ACPJC-2016-164-12-064)

Teale, E., Young, J., Siddiqi, N., Munyombwe, T., Harrison, J., Schuurmanns, M. (2016) Study protocol—investigation of the Delirium Observation Screening Scale (DOSS) for the routine detection of delirium in the care home setting: a prospective cohort study. BMJ Open, 6, (doi: 10.1136/bmjopen-2015-009615)

Al-Alshaikh, S., Quinn, T., Dunn, W., Walters, M., Dawson, J. (2016) Predictive factors of non-adherence to secondary preventative medication after stroke or transient ischaemic attack: A systematic review and meta-analyses. European Stroke Journal, 1, pp. 65-75. (doi: 10.1177/2396987316647187)

Bernhardt, J., Churilov, L., Ellery, F., Collier, J., Chamberlain, J., Langhorne, P., Lindley, R. I., Moodie, M., Dewey, H., Thrift, A. G. (2016) Prespecified dose-response analysis for a very early rehabilitation trial (AVERT) Neurology, 86, pp. 2138-2145. (doi: 10.1212/wnl.0000000000002459)

Pollock, A., Brady, M. C., Farmer, S. E., Langhorne, P., Mead, G. E., Mehrholz, J., Wiffen, P. J., van Wijck, F. (2016) The purpose of rating quality of evidence differs in an overview, as compared to guidelines or recommendations. Journal of Clinical Epidemiology, 74, pp. 238-240. (doi: 10.1016/j.jclinepi.2016.01.001)

Ballantyne, M. D., Pinel, K., Dakin, R., Vesey, A. T., Diver, L., MacKenzie, R., Garcia, R., Welsh, P., Sattar, N., Hamilton, G., Joshi, N., Dweck, M. R., Miano, J. M., McBride, M. W., Newby, D. E., McDonald, R. A., Baker, A. H. (2016) Smooth muscle enriched long noncoding RNA (SMILR) regulates cell proliferation. Circulation, 133, pp. 2050-2065. (doi: 10.1161/circulationaha.115.021019)

Luker, J. A., Craig, L. E., Bennett, L., Ellery, F., Langhorne, P., Wu, O., Bernhardt, J. (2016) Implementing a complex rehabilitation intervention in a stroke trial: a qualitative process evaluation of AVERT. BMC Medical Research Methodology, 16, (doi: 10.1186/s12874-016-0156-9)

Brady, M.C., Jamieson, K., Bugge, C., Hagen, S., McClurg, D., Chalmers, C., Langhorne, P. (2016) Caring for continence in stroke care settings: a qualitative study of patients and staff perspectives on the implementation of a new continence care intervention. Clinical Rehabilitation, 30, pp. 481-494. (doi: 10.1177/0269215515589331)

Macisaac, R., Ali, M., Peters, M., English, C., Rodgers, H., Jenkinson, C., Quinn, T. J. (2016) Derivation and validation of a modified short form of the Stroke Impact Scale. Journal of the American Heart Association, 2016, (doi: 10.1161/JAHA.115.003108)

Geue, C., Wu, O., Leyland, A., Lewsey, J., Quinn, T. J. (2016) Geographic variation of inpatient care costs at the end of life. Age and Ageing, 45, pp. 376-381. (doi: 10.1093/ageing/afw040)

Rodrigues, F. B. A., Langhorne, P., Costa, J. (2016) Mechanical thrombectomy and functional outcomes after stroke. JAMA: Journal of the American Medical Association, 315, pp. 1791-1792. (doi: 10.1001/jama.2016.0383)

Wan Sulaiman, W.N., Caslake, M.J., Delles, C., Karlsson, H., Mulder, M.T., Graham, D., Freeman, D.J. (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130, pp. 491-497. (doi: 10.1042/cs20150475)

Harrison, J. K., McKay, I. K., Grant, P., Hannah, J., Quinn, T. J. (2016) Appropriateness of unscheduled hospital admissions from care homes. Clinical Medicine, 16, pp. 103-108. (doi: 10.7861/clinmedicine.16-2-103)

Diver, L. A., MacKenzie, S. M., Fraser, R., McManus, F., Freel, E. M., Alvarez-Madrazo, S., McClure, J. D., Friel, E. C., Hanley, N. A., Dominiczak, A. F., Caulfield, M. J., Munroe, P. B., Connell, J. M., Davies, E. (2016) Common polymorphisms at the CYP17A1 locus associate with steroid phenotype: support for blood pressure genome-wide association study signals at this locus. Hypertension, 67, pp. 724-732. (doi: 10.1161/HYPERTENSIONAHA.115.06925)

Robson, R., Lacey, A. S., Luzio, S. D., Van Woerden, H., Heaven, M. L., Wani, M., Halcox, J. P. J., Castilla-Guerra, L., Dawson, J., Hewitt, J. (2016) HbA1c measurement and relationship to incident stroke. Diabetic Medicine, 33, pp. 459-462. (doi: 10.1111/dme.13057)

Arba, F., Ali, M., Quinn, T. J., Hankey, G. J., Lees, K. R., Inzitari, D. (2016) Lacunar Infarcts, depression, and anxiety symptoms one year after stroke. Journal of Stroke and Cerebrovascular Diseases, 25, pp. 831-834. (doi: 10.1016/j.jstrokecerebrovasdis.2015.12.018)

Al AlShaikh, S., Quinn, T., Dunn, W., Walters, M., Dawson, J. (2016) Multimodal interventions to enhance adherence to secondary preventive medication after stroke: a systematic review and meta-analyses. Cardiovascular Therapeutics, 34, pp. 85-93. (doi: 10.1111/1755-5922.12176)

Hewitt, J., Walters, M., Padmanabhan, S., Dawson, J. (2016) Cohort profile of the UK Biobank: diagnosis and characteristics of cerebrovascular disease. BMJ Open, 6, (doi: 10.1136/bmjopen-2015-009161)

Quinn, T. J. (2016) Forward thinking: where next for delirium prevention research? Cochrane Database of Systematic Reviews, 2016, (doi: 10.1002/14651858.ED000110)

Siddiqi, N., Harrison, J.K., Clegg, A., Teale, E.A., Young, J., Taylor, J., Simpkins, S.A. (2016) Interventions for preventing delirium in hospitalised non-ICU patients (Review) Cochrane Database of Systematic Reviews, (doi: 10.1002/14651858.CD005563.pub3)

Durussel, J., Haile, D., Mooses, K., Daskalaki, E., Beattie, W., Mooses, M., Mekonen, W., Ongaro, N., Anjila, E., Patel, R., Padmanabhan, N., McBride, M., McClure, J., Pitsiladis, Y. (2016) Blood transcriptional signature of recombinant human erythropoietin administration and implications for antidoping strategies. Physiological Genomics, 48, pp. 202-209. (doi: 10.1152/physiolgenomics.00108.2015)

MacIsaac, R., Janek, S., Higgins, P., Walters, M. R., Padmanabhan, S., Dominiczak, A. F., Touyz, R. M., Dawson, J. (2016) Allopurinol and cardiovascular outcomes in adults with hypertension. Hypertension, 67, pp. 535-540. (doi: 10.1161/HYPERTENSIONAHA.115.06344)

Chouchani, E. T., Pell, V. R., James, A. M., Work, L. M., Saeb-Parsy, K., Frezza, C., Krieg, T., Murphy, M. P. (2016) A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury. Cell Metabolism, 23, pp. 254-263. (doi: 10.1016/j.cmet.2015.12.009)

Pollock, A., Farmer, S. E., Brady, M. C., Langhorne, P., Mead, G. E., Mehrholz, J., van Wijck, F., Wiffen, P. J. (2016) An algorithm was developed to assign GRADE levels of evidence to comparisons within systematic reviews. Journal of Clinical Epidemiology, 70, pp. 106-110. (doi: 10.1016/j.jclinepi.2015.08.013)

Jones, F. E., Bailey, M. A., Murray, L. S., Lu, Y., McNeilly, S., Schlötzer-Schrehardt, U., Lennon, R., Sado, Y., Brownstein, D. G., Mullins, J. J., Kadler, K. E., Van Agtmael, T. (2016) ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice. Disease Models and Mechanisms, 9, pp. 165-76. (doi: 10.1242/dmm.021741)

Pulit, S. L. et al. (2016) Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. Lancet Neurology, 15, pp. 174-184. (doi: 10.1016/S1474-4422(15)00338-5)

Khan, A. A., Quinn, T. J., Hewitt, J., Fan, Y., Dawson, J. (2016) Serum uric acid level, and association with cognitive impairment and dementia: systematic review and meta-analysis. Age, 38, (doi: 10.1007/s11357-016-9871-8)

Turner, M., Barber, M., Dodds, H., Dennis, M., Langhorne, P., Macleod, M.-J. (2016) Stroke patients admitted within normal working hours are more likely to achieve process standards and to have better outcomes. Journal of Neurology, Neurosurgery and Psychiatry, 87, pp. 138-143. (doi: 10.1136/jnnp-2015-311273)

McGovern, A., Pendlebury, S. T., Mishra, N. k., Fan, Y., Quinn, T. J. (2016) Test accuracy of informant-based cognitive screening tests for diagnosis of dementia and multidomain cognitive impairment in stroke. Stroke, 47, pp. 329-335. (doi: 10.1161/strokeaha.115.011218)

Alim, M., Lindley, R., Felix, C., Gandhi, D. B. C., Verma, S. J., Tugnawat, D. K., Syrigapu, A., Anderson, C. S., Ramamurthy, R. K., Langhorne, P., Murthy, G. V. S., Shamanna, B. R., Hackett, M. L., Maulik, P. K., Harvey, L. A., Jan, S., Liu, H., Walker, M., Forster, A., Pandian, J. D. (2016) Family-led rehabilitation after stroke in India: the ATTEND trial, study protocol for a randomized controlled trial. Trials, 17, (doi: 10.1186/s13063-015-1129-8)

Small, H. Y., Morgan, H., Beattie, E., Griffin, S., Indahl, M., Delles, C., Graham, D. (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022)

Abdul-Rahim, A. H., Quinn, T. J., Alder, S., Clark, A. B., Musgrave, S., Langhorne, P., Potter, J. F., Myint, P. K. (2016) Derivation and validation of a novel prognostic scale (modified–stroke subtype, Oxfordshire community stroke project classification, age, and prestroke modified rankin) to predict early mortality in acute stroke. Stroke, 47, pp. 74-79. (doi: 10.1161/strokeaha.115.009898)

Dawson, J., Pierce, D., Dixit, A., Kimberley, T. J., Robertson, M., Tarver, B., Hilmi, O., McLean, J., Forbes, K., Kilgard, M. P., Rennaker, R. L., Cramer, S. C., Walters, M., Engineer, N. (2016) Safety, feasibility, and efficacy of vagus nerve stimulation paired with upper-limb rehabilitation after ischemic stroke. Stroke, 47, pp. 143-150. (doi: 10.1161/STROKEAHA.115.010477)

Scholz, A.F.W., Oldroyd, C., McCarthy, K., Quinn, T.J., Hewitt, J. (2016) Systematic review and meta-analysis of risk factors for postoperative delirium among older patients undergoing gastrointestinal surgery. British Journal of Surgery, 103, pp. e21-e28. (doi: 10.1002/bjs.10062)

Boulberdaa, M., Scott, E., Ballantyne, M., Garcia, R., Descamps, B., Angelini, G. D., Brittan, M., Hunter, A., McBride, M., McClure, J., Miano, J. M., Emanueli, C., Mills, N. L., Mountford, J. C., Baker, A. H. (2016) A role for the long non-coding RNA SENCR in commitment and function of endothelial cells. Molecular Therapy, 24, pp. 978-990. (doi: 10.1038/mt.2016.41)

Kishore, A. K., Vail, A., Bray, B. D., Chamorro, A., Napoli, M. D., Kalra, L., Langhorne, P., Montaner, J., Roffe, C., Rudd, A. G., Tyrrell, P. J., de Beek, D. v., Woodhead, M., Meisel, A., Smith, C. J. (2016) Clinical risk scores for predicting stroke-associated pneumonia: a systematic review. European Stroke Journal, 1, pp. 76-84. (doi: 10.1177/2396987316651759)

Hendry, K., Quinn, T. J., Evans, J., Scortichini, V., Miller, H., Burns, J., Cunnington, A., Stott, D. J. (2016) Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study. Age and Ageing, 45, pp. 832-837. (doi: 10.1093/ageing/afw130)

Horikoshi, M. et al. (2016) Genome-wide associations for birth weight and correlations with adult disease. Nature, 538, pp. 248-252. (doi: 10.1038/nature19806)

O'Donnell, M. J. et al. (2016) Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study. Lancet, 388, pp. 761-775. (doi: 10.1016/S0140-6736(16)30506-2)

Brkic, L., Shaw, L., van Wijck, F., Francis, R., Price, C., Forster, A., Langhorne, P., Watkins, C., Rodgers, H. (2016) Repetitive arm functional tasks after stroke (RAFTAS): a pilot randomised controlled trial. Pilot and Feasibility Studies, 2, (doi: 10.1186/s40814-016-0088-5)

Hoffmann, T.C., Walker, M.F., Langhorne, P., Eames, S., Thomas, E., Glasziou, P. (2016) What's in a name? The challenge of describing interventions in systematic reviews: analysis of a random sample of reviews of non-pharmacological stroke interventions. BMJ Open, 5, (doi: 10.1136/bmjopen-2015-009051)

2015

Bernhardt, J., Lindley, R. I., Lalor, E., Ellery, F., Chamberlain, J., Van Holsteyn, J., Collier, J. M., Dewey, H. M., Parsons, B., Moodie, M., Lennon, S., Donnan, G. A., Thrift, A. G., Churilov, L., Langhorne, P. (2015) AVERT2(a very early rehabilitation trial, a very effective reproductive trigger): retrospective observational analysis of the number of babies born to trial staff. British Medical Journal, 351, (doi: 10.1136/bmj.h6432)

Turner, M., Barber, M., Dodds, H., Dennis, M., Langhorne, P., Macleod, M.-J. (2015) Agreement between routine electronic hospital discharge and Scottish stroke care audit (SSCA) data in identifying stroke in the Scottish population. BMC Health Services Research, 15, (doi: 10.1186/s12913-015-1244-y)

Wilson, C., Kerr, D., Noel-Storr, A., Quinn, T. (2015) Associations with publication and assessing publication bias in dementia diagnostic test accuracy studies. International Journal of Geriatric Psychiatry, 30, pp. 1250-1256. (doi: 10.1002/gps.4283)

Singh, J., McElroy, M., Quinn, T. (2015) Feasibility of recommended cognitive screening tools for older adults in carehomes. Journal of the American Geriatrics Society, 63, pp. 2432-2434. (doi: 10.1111/jgs.13808)

Deng, L., Blanco Lopez, F. J., Stevens, H., Lu, R., Caudrillier, A., McBride, M., McClure, J. D., Grant, J., Thomas, M., Frid, M., Stenmark, K., White, K., Seto, A. G., Morrell, N. W., Bradshaw, A. C., MacLean, M. R., Baker, A. H. (2015) MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circulation Research, 117, pp. 870-883. (doi: 10.1161/CIRCRESAHA.115.306806)

Norrving, B., Bray, B. D., Asplund, K., Heuschmann, P., Langhorne, P., Rudd, A. G., Wagner, M., Wiedmann, S., Wolfe, C. D.A. (2015) Cross-national key performance measures of the quality of acute stroke care in Western Europe. Stroke, 46, pp. 2891-2895. (doi: 10.1161/strokeaha.115.008811)

Akehurst, C., Small, H., Sharafetdinova, L., Forrest, R., Beattie, W., Brown, C. E., Robinson, S. W., McClure, J. D., Work, L. M., Carty, D. M., McBride, M. W., Freeman, D. J., Delles, C. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33, pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656)

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892)

Harrison, J. K., Clegg, A., Conroy, S. P., Young, J. (2015) Managing frailty as a long-term condition. Age and Ageing, 44, pp. 732-735. (doi: 10.1093/ageing/afv085)

Findlay, M. D., Thomson, P. C., Fulton, R. L., Solbu, M. D., Jardine, A. G., Patel, R. K., Stevens, K. K., Geddes, C. C., Dawson, J., Mark, P. B. (2015) Risk factors of ischemic stroke and subsequent outcome in hemodialysis patients. Stroke, 46, pp. 2477-2481. (doi: 10.1161/STROKEAHA.115.009095)

Borghi, C., Rosei, E. A., Bardin, T., Dawson, J., Dominiczak, A., Kielstein, J. T., Manolis, A. J., Perez-Ruiz, F., Mancia, G. (2015) Serum uric acid and the risk of cardiovascular and renal disease. Journal of Hypertension, 33, pp. 1729-1741. (doi: 10.1097/HJH.0000000000000701)

Quinn, T. J., Alghamdi, J., Padmanabhan, S., Porteous, D. J., Smith, B. H., Hocking, L., Deary, I. J., Gallacher, J., Messow, M., Stott, D. J. (2015) Association between cognition and gene polymorphisms involved in thrombosis and haemostasis. Age, 37, pp. 80. (doi: 10.1007/s11357-015-9820-y)

Brady, M. C., Stott, D., Weir, C. J., Chalmers, C., Sweeney, P., Donaldson, C., Barr, J., Barr, M., Pollock, A., McGowan, S., Bowers, N., Langhorne, P. (2015) Clinical and cost effectiveness of enhanced oral healthcare in stroke care settings (SOCLE II): a pilot, stepped wedge, cluster randomized, controlled trial protocol. International Journal of Stroke, 10, pp. 979-984. (doi: 10.1111/ijs.12530)

Ponomarev, D., Miller, C., Govan, L., Haig, C., Wu, O., Langhorne, P. (2015) Complications following incident stroke resulting in readmissions: an analysis of data from three Scottish health surveys. International Journal of Stroke, 10, pp. 911-917. (doi: 10.1111/ijs.12191)

Schanstra, J.P. et al. (2015) Diagnosis and prediction of CKD progression by assessment of urinary peptides. Journal of the American Society of Nephrology, 26, pp. 1999-2010. (doi: 10.1681/asn.2014050423)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544)

Bernhardt, J., Langhorne, P., Lindley, R. I., Thrift, A. G., Ellery, F., Collier, J., Churilov, L., Moodie, M., Dewey, H., Donnan, G. (2015) Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial. Lancet, 386, pp. 46-55. (doi: 10.1016/S0140-6736(15)60690-0)

Brown, L., Forster, A., Young, J., Crocker, T., Benham, A., Langhorne, P. (2015) Medical day hospital care for older people versus alternative forms of care. Cochrane Database of Systematic Reviews, (doi: 10.1002/14651858.CD001730.pub3)

McDonald, R. A., Halliday, C. A., Miller, A. M., Diver, L. A., Dakin, R. S., Montgomery, J., McBride, M. W., Kennedy, S., McClure, J. D., Robertson, K. E., Douglas, G., Channon, K. M., Oldroyd, K., Baker, A. H. (2015) Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation. Journal of the American College of Cardiology, 65, pp. 2314-2327. (doi: 10.1016/j.jacc.2015.03.549)

Pandian, J. D., Felix, C., Kaur, P., Sharma, D., Julia, L., Toor, G., Arora, R., Gandhi, D. B.C., Verma, S. J., Anderson, C. S., Langhorne, P., Murthy, G.V.S., Hackett, M. L., Maulik, P. K., Alim, M., Harvey, L. A., Jan, S., Walker, M., Forster, A., Lindley, R. (2015) FAmily-led rehabiliTaTion aftEr stroke in INDia: the ATTEND pilot study. International Journal of Stroke, 10, pp. 609-614. (doi: 10.1111/ijs.12475)

Fulton, R. L., Walters, M. R., Morton, R., Touyz, R. M., Dominiczak, A. F., Morrison, D. S., Padmanabhan, S., Meredith, P. A., McInnes, G. T., Dawson, J. (2015) Acetaminophen use and risk of myocardial infarction and stroke in a hypertensive cohort. Hypertension, 65, pp. 1008-U596. (doi: 10.1161/HYPERTENSIONAHA.114.04945)

Kishore, A. K., Vail, A., Chamorro, A., Garau, J., Hopkins, S. J., Di Napoli, M., Kalra, L., Langhorne, P., Montaner, J., Roffe, C., Rudd, A. G., Tyrrell, P. J., van de Beek, D., Woodhead, M., Meisel, A., Smith, C. J. (2015) How is pneumonia diagnosed in clinical stroke research?: a systematic review and meta-analysis. Stroke, 46, pp. 1202-1209. (doi: 10.1161/STROKEAHA.114.007843)

Ali, M., Lyden, P., Brady, M. (2015) Aphasia and dysarthria in acute stroke: recovery and functional outcome. International Journal of Stroke, 10, pp. 400-406. (doi: 10.1111/ijs.12067)

Turner, M., Barber, M., Dodds, H., Murphy, D., Dennis, M., Langhorne, P., Macleod, M.-J. (2015) mplementing a simple care bundle is associated with improved outcomes in a national cohort of patients with ischemic stroke. Stroke, 46, pp. 1065-1070. (doi: 10.1161/STROKEAHA.114.007608)

Rannikmäe, K. et al. (2015) Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease. Neurology, 84, pp. 918-926. (doi: 10.1212/WNL.0000000000001309)

Watt, T., Barbesino, G., Bjorner, J. B., Bonnema, S. J., Bukvic, B., Drummond, R., Groenvold, M., Hegedüs, L., Kantzer, V., Lasch, K. E., Marcocci, C., Mishra, A., Netea-Maier, R., Ekker, M., Paunovic, I., Quinn, T. J., Rasmussen, Å. K., Russell, A., Sabaretnam, M., Smit, J., Törring, O., Zivaljevic, V., Feldt-Rasmussen, U. (2015) Cross-cultural validity of the thyroid-specific quality-of-life patient-reported outcome measure, ThyPRO. Quality of Life Research, 24, pp. 769-780. (doi: 10.1007/s11136-014-0798-1)

Harrison, J. K., Clipsham, L. E., Cooke, C. M., Warwick, G., Burton, J. O. (2015) Establishing a supportive care register improves end-of-life care for patients with advanced chronic kidney disease. Nephron, 129, pp. 209-213. (doi: 10.1159/000371888)

Skogstrand, T., Leh, S., McClure, J., Dashti, M., Iversen, B. M., Graham, D., McBride, M., Hultström, M. (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33, pp. 584-596. (doi: 10.1097/HJH.0000000000000395)

Hendry, K., Hill, E., Quinn, T. J., Evans, J., Stott, D. J. (2015) Single screening questions for cognitive impairment in older people: a systematic review. Age and Ageing, 44, pp. 322-326. (doi: 10.1093/ageing/afu167)

McManus, F., Fraser, R., Davies, E., Connell, J.M.C., Freel, E.M. (2015) Plasma steroid profiling and response to trophins to illustrate intra-adrenal dynamics. Journal of Endocrinology, 224, pp. 149-157. (doi: 10.1530/JOE-14-0561)

Brainin, M., Tuomilehto, J., Heiss, W.-D., Bornstein, N.M., Bath, P.M.W., Teuschl, Y., Richard, E., Guekht, A., Quinn, T. (2015) Post-stroke cognitive decline: an update and perspectives for clinical research. European Journal of Neurology, 22, pp. 229-e16. (doi: 10.1111/ene.12626)

Bernhardt, J., Churilov, L., Dewey, H., Lindley, R. I., Moodie, M., Collier, J., Langhorne, P., Thrift, A. G., Donnan, G. (2015) Statistical analysis plan (SAP) for A Very Early Rehabilitation Trial (AVERT): an international trial to determine the efficacy and safety of commencing out of bed standing and walking training (very early mobilization) within 24 h of stroke onset vs. usual stroke unit care. International Journal of Stroke, 10, pp. 23-24. (doi: 10.1111/ijs.12423)

Jongstra, S., Harrison, J. K., Quinn, T. J., Richard, E. (2015) Antihypertensive withdrawal for the prevention of cognitive decline. Cochrane Database of Systematic Reviews, 11, (doi: 10.1002/14651858.CD011971)

Harrison, J.K., Shenkin, S.D. (2015) Body mass index and the risk of dementia – what do we know and what should we do? Journal of the Royal College of Physicians of Edinburgh, 45, pp. 141-142. (doi: 10.4997/JRCPE.2015.211)

Ritchie, C. W., Terrera, G. M., Quinn, T. J. (2015) Dementia trials and dementia tribulations: methodological and analytical challenges in dementia research. Alzheimer's Research and Therapy, 7, (doi: 10.1186/s13195-015-0113-6)

Smith, C. J., Kishore, A. K., Vail, A., Chamorro, A., Garau, J., Hopkins, S. J., Di Napoli, M., Kalra, L., Langhorne, P., Montaner, J., Roffe, C., Rudd, A. G., Tyrrell, P. J., van de Beek, D., Woodhead, M., Meisel, A. (2015) Diagnosis of stroke-associated pneumonia recommendations from the pneumonia in stroke consensus group. Stroke, 46, pp. 2335-2340. (doi: 10.1161/strokeaha.115.009617)

Bernhardt, J., Raffelt, A., Churilov, L., Lindley, R. I., Speare, S., Ancliffe, J., Katijjahbe, M. A., Hameed, S., Lennon, S., McRae, A., Tan, D., Quiney, J., Williamson, H. C., Collier, J., Dewey, H. M., Donnan, G. A., Langhorne, P., Thrift, A. G. (2015) Exploring threats to generalisability in a large international rehabilitation trial (AVERT) BMJ Open, 5, (doi: 10.1136/bmjopen-2015-008378)

Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S., Porteous, D. J., Starr, J., Deary, I. J., Wardlaw, J. M. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46, pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649)

Harrison, J. K., Fearon, P., Noel-Storr, A. H., McShane, R., Stott, D. J., Quinn, T. J. (2015) Informant questionnaire on cognitive decline in the elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. Cochrane Database of Systematic Reviews, 2015, (doi: 10.1002/14651858.CD010772.pub2)

Hendry, K., Quinn, T. J., Evans, J. J., Stott, D. J. (2015) Informant single screening questions for delirium and dementia in acute care – a cross-sectional test accuracy pilot study. BMC Geriatrics, 15, (doi: 10.1186/s12877-015-0016-1)

Fisher, J.M., Harrison, J.K. (2015) Pushing the boundaries of geriatric medicine. Journal of the Royal College of Physicians of Edinburgh, 45, pp. 154-155.

Lewsey, J., Ebueku, O., Jhund, P. S., Gillies, M., Chalmers, J. W.T., Redpath, A., Briggs, A., Walters, M., Langhorne, P., Capewell, S., McMurray, J. J.V., MacIntyre, K. (2015) Temporal trends and risk factors for readmission for infections, gastrointestinal and immobility complications after an incident hospitalisation for stroke in Scotland between 1997 and 2005. BMC Neurology, 15, (doi: 10.1186/s12883-014-0257-1)

Turner, M., Barber, M., Dodds, H., Dennis, M., Langhorne, P., Macleod, M. J. (2015) The impact of stroke unit care on outcome in a Scottish stroke population, taking into account case mix and selection bias. Journal of Neurology, Neurosurgery and Psychiatry, 86, pp. 314-318. (doi: 10.1136/jnnp-2013-307478)

Cannon, J. A., McMurray, J. J.V., Quinn, T. J. (2015) ‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure. Alzheimer's Research and Therapy, 7, (doi: 10.1186/s13195-015-0106-5)

PGR Students

Gabriela Gerganova

  • Postgraduate Research Student
  • Research title: Inflammatory mechanisms after ischaemic stroke

Stroke research has always been a particular strength at the University of Glasgow. Our teams build upon this strong foundation but have widened the stroke remit to include research in vascular cognitive impairment, conducting clinical trials and fundamental pre-clinical research focusing on molecular underpinnings of cerebrovascular disease to develop novel therapeutic avenues.

Our work is characterized by a close collaboration between pre-clinical and clinical researchers. Active areas of collaboration include but are not limited to, genetics of stroke syndromes, big data, and primary-care based interventions. This approach has delivered impactful research, recent successes include bringing to market the first FDA approved neuro-rehabilitative technology, creating training and guidance that is now considered the industry standard, and leading multi-centre trials in fields of assessment, prevention, and neuroprotection.

Many of our research team have clinical positions and are co-located with high volume specialist stroke centres including the West of Scotland Thrombectomy hub, which is equipped with advanced imaging facilities including 7T MRI.

We are proud to work in partnership with stroke survivors and others who have lived experience of stroke. We manage the national stroke survivor research user group and coordinate an active program of public outreach and education. Our members have leadership positions in the most important UK and International scientific and professional societies with a focus on stroke.

Ongoing research topics include:

  • Developing and assessing novel neurorehabilitation interventions.
  • Improving the conduct of clinical trials with an emphasis on outcome assessment.
  • Understanding and treating post stroke cognitive disorders.
  • Improving the detection of atrial fibrillation to prevent stroke.
  • Investigating the role of the extracellular matrix in cerebrovascular diseases.
  • Profiling of cargo in circulating extracellular vesicles as a potential biomarker of stroke and/or cerebrovascular disease.
  • Combining gene and drug intervention strategies or using microRNAs to improve neurological recovery following experimental stroke.