Vascular Structure & Function

Our group are interested in all aspects of the active process of vascular remodeling and structural change, including cell growth, death, migration, and the synthesis or degradation of the extracellular matrix. 

Staff

Publications

2024

Ramses, R., Kennedy, S., Good, R., Oldroyd, K. G., Mcginty, S. (2024) Performance of drug-coated balloons in coronary and below-the-knee arteries: anatomical, physiological and pathological considerations. Vascular Pharmacology, 155, (doi: 10.1016/j.vph.2024.107366)

Carberry, J., Petrie, M. C., Lee, M. M.Y., Brooksbank, K., Campbell, R. T., Good, R., Jhund, P. S., Kellman, P., Lang, N. N., Mangion, K., Mark, P. B., McConnachie, A., McMurray, J. J.V., Meyer, B., Orchard, V., Shaukat, A., Watkins, S., Welsh, P., Sattar, N., Berry, C., Docherty, K. F. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure,

Hanson Ng, Y. Y., Dora, K. A., Lemmey, H. A. L., Lin, J., Alden, J., Wallis, L., Donovan, L., Shorthose, O., Leiper, F. C., Leiper, J., Garland, C. J. (2024) Asymmetric dimethylarginine enables depolarizing spikes and vasospasm in mesenteric and coronary resistance arteries. Hypertension, 81, pp. 764-775. (doi: 10.1161/HYPERTENSIONAHA.123.22454)

Yang, Y., Husmeier, D., Gao, H., Berry, C., Carrick, D., Radjenovic, A. (2024) Automatic detection of myocardial ischaemia using generalisable spatio-temporal hierarchical Bayesian modelling of DCE-MRI. Computerized Medical Imaging and Graphics, 113, (doi: 10.1016/j.compmedimag.2024.102333)

Lim, M. W. S., Lucas-Herald, A. K., Mason, A., Delles, C., Connelly, P. J. (2024) Sex differences in the cardiovascular effects of GnRH analogues. Journal of Endocrinology, 261, (doi: 10.1530/JOE-23-0309)

Kobayashi, M., Ferreira, J. P., Kevin, D., Bresso, E., Huttin, O., Bozec, E., Brunner La Rocca, H.-P., Delles, C., Clark, A. L., Edelmann, F., González, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A.J., Rossignol, P., Cleland, J. G.F., Zannad, F., Girerd, N. (2024) Proteomic profiles of left atrial volume and its influence on response to spironolactone: findings from the HOMAGE trial and STANISLAS cohort. European Journal of Heart Failure,

Ang, D. T.Y., Carrick, D., Kamdar, A., Sykes, R., McGeoch, R. J., Collison, D., McConnachie, A., Berry, C. (2024) Intracoronary adenosine derived coronary flow reserve and index of microvascular resistance. Circulation: Cardiovascular Interventions,

Alghanimy, A., Work, L. M., Holmes, W. M. (2024) The glymphatic system and multiple sclerosis: An evolving connection. Multiple Sclerosis and Related Disorders, 83, (doi: 10.1016/j.msard.2024.105456)

Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, (doi: 10.1038/s43856-024-00455-5)

Rossitto, G., Bertoldi, G., Rutkowski, J. M., Mitchell, B. M., Delles, C. (2024) Sodium, interstitium, lymphatics, and hypertension - A tale of hydraulics: Salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.17942)

Loughrey, C. et al. (2024) A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic action: Pre-clinical and phase I study. British Journal of Pharmacology,

Sykes, R., Hanna, R., Berry, C. (2024) Prognostic importance of fractional flow reserve and left ventricular systolic dysfunction after percutaneous coronary intervention. JACC: Asia, (doi: 10.1016/j.jacasi.2023.12.002)

Hoare, D., Kingsmore, D., Holsgrove, M., Russell, E., Kirimi, M. T., Czyzewski, J., Mirzai, N., Kennedy, S., Neale, S. L., Mercer, J. R. (2024) Realtime monitoring of thrombus formation in vivo using a self-reporting vascular access graft. Communications Medicine, 4, (doi: 10.1038/s43856-024-00436-8)

Olowoyo, P. et al. (2024) Priorities to reduce the burden of hypertension in Africa through ACHIEVE. Lancet Global Health, 12, pp. e192-e193. (doi: 10.1016/S2214-109X(23)00540-5)

Mary, S., Conti-Ramsden, F., Boder, P., Parveen, H., Setjiadi, D., Fleminger, J., Brockbank, A., Graham, D., Bramham, K., Chappell, L. C., Delles, C. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6)

Kharlamov, A., Sherriff, N., Delles, C., van der Harst, P. (2024) Tackling cardiovascular healthcare disparities for LGBTQIA+ population: a call to action in the European Society of Cardiology. European Heart Journal, (doi: 10.1093/eurheartj/ehad882)

McFall, A., Graham, D., Nicklin, S. A., Work, L. M. (2024) Unscheduled changes in pre-clinical stroke model housing contributes to variance in physiological and behavioural data outcomes: a post hoc analysis. Brain and Neuroscience Advances, 8, (doi: 10.1177/23982128241238934)

2023

Glen, C., Morrow, A., Roditi, G., Hopkins, T., Macpherson, I., Stewart, P., Petrie, M. C., Berry, C., Epstein, F., Lang, N. N., Mangion, K. (2023) Cardiovascular sequalae of trastuzumab and anthracycline in long-term survivors of breast cancer. Heart, (doi: 10.1136/heartjnl-2023-323437)

Freeman-Jones, E., Miller, W. H., Work, L. M., Fullerton, J. L. (2023) Polypathologies and animal models of traumatic brain injury. Brain Sciences, 13, (doi: 10.3390/brainsci13121709)

Bagordo, D., Rossi, G. P., Delles, C., Wiig, H., Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.123.19569)

Neupane, D., Mukhtar, Q., Krajan Pardo, E. K., Acharya, S. D., Delles, C., Sharman, J. E., Cobb, L., Lackland, D. T., Moran, A., Weber, M. A., Olsen, M. H. (2023) Emerging Authors Program for building cardiovascular disease prevention and management research capacity in low- and middle-income countries: a collaboration of the U.S. Centers for Disease Control and Prevention, the Lancet Commission on Hypertension Group, Resolve to Save Lives, and the World Hypertension League. Journal of Human Hypertension, pp. -023. (doi: 10.1038/s41371-023-00880-4)

Lyon, M., Fullerton, J. L., Kennedy, S., Work, L. M. (2023) Hypertension & dementia: pathophysiology & potential utility of antihypertensives in reducing disease burden. Pharmacology and Therapeutics, (doi: 10.1016/j.pharmthera.2023.108575)

Connelly, P., Osmanska, J., Lee, M. M.Y., Delles, C., McEntegart, M. B., Byrne, J. (2023) A case report of myocardial infarction in a young transgender man with testosterone therapy? raising awareness on healthcare issues in the transgender community and a call for further research. European Heart Journal: Case Reports, 7, (doi: 10.1093/ehjcr/ytad562)

McErlane, J., McCall, P., Willder, J., Berry, C., Shelley, B. (2023) Cardiac biomarkers and right ventricular dysfunction are independently associated with one year mortality in patients with COVID-19 receiving mechanical ventilation: a prospective cohort study. CHEST Critical Care, 1, (doi: 10.1016/j.chstcc.2023.100015)

Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7, pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)

Desson, Z., Sharman, J. E., Searles, A., Schutte, A. E., Delles, C., Olsen, M. H., Ordunez, P., Hure, A., Morton, R., Figtree, G., Webster, J., Jennings, G., Redfern, J., Nicolls, S., McNamara, M., Deeming, S., Doyle, K., Ramanathan, S. (2023) Improving the accuracy of blood pressure measuring devices in Australia: a modelled return on investment study. Journal of Human Hypertension, (doi: 10.1038/s41371-023-00866-2)

Murphy, C. N., Delles, C., Davies, E., Connelly, P. J. (2023) Cardiovascular disease in transgender individuals. Atherosclerosis, 384, (doi: 10.1016/j.atherosclerosis.2023.117282)

Martin, T. P., MacDonald, E. A., Bradley, A., Watson, H., Saxena, P., Rog-Zielinska, E. A., Raheem, A., Fisher, S., Elbassioni, A. A. M., Almuzaini, O., Booth, C., Campbell, M., Riddell, A., Herzyk, P., Blyth, K., Nixon, C., Zentilin, L., Berry, C., Braun, T., Giacca, M., McBride, M. W., Nicklin, S. R., Cameron, E. R., Loughrey, C. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119, pp. 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107)

Sri, S. et al. (2023) A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia. Cerebral Circulation - Cognition and Behavior, 5, (doi: 10.1016/j.cccb.2023.100189)

Sidik, N. P., Stanley, B., Sykes, R., Morrow, A. J., Bradley, C. P., Mcdermott, M., Ford, T., Roditi, G., Hargreaves, A., Stobo, D., Adams, J., Byrne, J., Mahrous, A., Young, R., Carrick, D., McGeoch, R., Corcoran, D., Lang, N. N., Heggie, R., Wu, O., McEntegart, M. B., McConnachie, A., Berry, C. (2023) Invasive endotyping in patients with angina and no obstructive coronary artery disease: a randomized controlled trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.123.064751)

de Beer, D., MC. Mels, C., Schutte, A., Delles, C., Mary, S., Mullen, W., Mischak, H., Kruger, R. (2023) Urinary peptidomics and pulse wave velocity: The African-PREDICT study. Journal of Proteome Research, 22, pp. 3282-3289. (doi: 10.1021/acs.jproteome.3c00347)

Sykes, R., Doherty, D., Morrow, A., Mangion, K., Rushd, A., Berry, C. (2023) NT-proBNP in patients presenting with myocardial infarction and non-obstructive coronary arteries without left ventricular systolic dysfunction. American Heart Journal Plus: Cardiology Research and Practice, 33, (doi: 10.1016/j.ahjo.2023.100311)

Keast, T., McErlane, J., Kearns, R., McKinlay, S., Raju, I., Watson, M., Robertson, K. E., Berry, C., Greenlaw, N., Ackland, G., McCall, P., Shelley, B. (2023) Study protocol for IMPRoVE: a multicentre prospective observational cohort study of the incidence, impact and mechanisms of perioperative right ventricular dysfunction in non-cardiac surgery. BMJ Open, 13, (doi: 10.1136/bmjopen-2023-074687)

Ranasinghe, S., Merz, C. N. B., Khan, N., Wei, J., George, M., Berry, C., Chieffo, A., Camici, P. G., Crea, F., Kaski, J. C., Marzilli, M., Gulati, M. (2023) Sex differences in Quality of Life in Patients with Ischemia with No Obstructive Coronary Artery Disease (INOCA): A Patient Self-Report Retrospective Survey from INOCA International. Journal of Clinical Medicine, 12, (doi: 10.3390/jcm12175646)

Bradley, C. P., Orchard, V., McKinley, G., Heggie, R., Wu, O., Good, R., Watkins, S., Lindsay, M., Eteiba, H., McGowan, J., McGeoch, R., Corcoran, D., Kellman, P., McConnachie, A., Berry, C. (2023) The coronary microvascular angina cardiovascular magnetic resonance imaging trial: rationale and design. American Heart Journal, (doi: 10.1016/j.ahj.2023.08.067)

Berry, C., McClure, J. D., Oldroyd, K. (2023) Death at 5-years in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a pooled analysis. European Heart Journal,

Mangion, K., Morrow, A. J., Sykes, R., Kamdar, A., Bagot, C., Bruce, G., Connelly, P., Delles, C., Gibson, V. B., Gillespie, L., Hall Barrientos, P., Lennie, V., Roditi, G., Sattar, N., Stobo, D., Allwood-Spiers, S., McConnachie, A., Berry, C., CISCO-19 investigators, (2023) Post-COVID-19 illness and associations with sex and gender. BMC Cardiovascular Disorders, 23, (doi: 10.1186/s12872-023-03412-7)

Ohashi, H. et al. (2023) Fractional flow reserve guided stent optimisation in focal and diffuse coronary artery disease. Diagnostics, 13, (doi: 10.3390/diagnostics13152612)

Rigattieri, S., Barbato, E., Berry, C. (2023) Microvascular resistance reserve: a reference test of the coronary microcirculation? European Heart Journal, 44, pp. 2870-2872. (doi: 10.1093/eurheartj/ehad291)

Brown, C. E., Casey, H., Dominiczak, A. F., Kerr, S., Campbell, A., Delles, C. (2023) Impact of preeclampsia on cardiovascular events: an analysis of the Generation Scotland: Scottish family health study. Journal of Human Hypertension, 37, pp. 735-741. (doi: 10.1038/s41371-023-00812-2)

Sykes, R., Ang, D. T. Y., Berry, C. (2023) Invasive coronary microvascular function assessment: pharmacological versus exercise testing. Heart, 109, pp. 1130-1131. (doi: 10.1136/heartjnl-2023-322512)

Connelly, P. J., Delles, C. (2023) Journal of Human Hypertension special issue on sex and gender differences in hypertension. Journal of Human Hypertension, 37, pp. 587-588. (doi: 10.1038/s41371-023-00847-5)

Casey, H., Dennehy, N., Fraser, A., Lees, C., McEniery, C. M., Scott, K., Wilkinson, I. B., Delles, C. (2023) Placental syndromes and maternal cardiovascular health. Clinical Science, 137, pp. 1211-1224. (doi: 10.1042/CS20211130)

Olivera, S., Graham, D. (2023) Sex differences in preclinical models of hypertension. Journal of Human Hypertension, 37, pp. 619-625. (doi: 10.1038/s41371-022-00770-1)

Patel, T. R., Villines, T., Kramer, C. M., Kwong, R. Y., Raharjo, D. E., Kunadian, V., Berry, C. (2023) Great Debate: computed tomography coronary angiography should be the initial diagnostic test in suspected angina. European Heart Journal, 44, pp. 2366-2375. (doi: 10.1093/eurheartj/ehac597)

Morrow, A. J., McFarlane, R., Berry, C. (2023) Novel therapy for ischaemia with no obstructive coronary arteries. European Heart Journal, (doi: 10.1093/eurheartj/ehad391)

Smilowitz, N. R., Toleva, O., Chieffo, A., Perera, D., Berry, C. (2023) Coronary microvascular disease in contemporary clinical practice. Circulation: Cardiovascular Interventions, 16, pp. 386-395. (doi: 10.1161/CIRCINTERVENTIONS.122.012568)

De Beer, D., Mels, C. M.C., Schutte, A. E., Delles, C., Mary, S., Mullen, W., Latosinska, A., Mischak, H., Kruger, R. (2023) Identifying a urinary peptidomics profile for hypertension in young adults: the African-PREDICT study. Proteomics, 23, (doi: 10.1002/pmic.202200444)

Rabbani, A., Gao, H., Lazarus, A., Dalton, D., Ge, Y., Mangion, K., Berry, C., Husmeier, D. (2023) Image-based estimation of the left ventricular cavity volume using deep learning and Gaussian process with cardio-mechanical applications. Computerized Medical Imaging and Graphics, 106, (doi: 10.1016/j.compmedimag.2023.102203)

Angelov, A., Connelly, P. J., Delles, C., Kararigas, G. (2023) Sex-biased and sex hormone-dependent regulation of apolipoprotein A1. Current Opinion in Physiology, 33, (doi: 10.1016/j.cophys.2023.100654)

Sykes, R. A., Neves, K. B., Alves-Lopes, R., Caputo, I., Jamieson, N. B., Kamdar, A., Legrini, A., Leslie, H., McIntosh, A., McConnachie, A., Morrow, A., McFarlane, R. W., Mangion, K., McAbney, J., Montezano, A. C., Touyz, R. M., Wood, C., Berry, C. (2023) Vascular mechanisms of post-COVID-19 conditions: rho-kinase is a novel target for therapy. European Heart Journal: Cardiovascular Pharmacotherapy, 9, pp. 371-386. (doi: 10.1093/ehjcvp/pvad025)

Arisido, M. W., Foco, L., Shoemaker, R., Melotti, R., Delles, C., Gögele, M., Barolo, S., Baron, S., Azizi, M., Dominiczak, A. F., Zennaro, M.-C., P. Pramstaller, P., Poglitsch, M., Pattaro, C. (2023) Cluster analysis of angiotensin biomarkers to identify antihypertensive drug treatment in population studies. BMC Medical Research Methodology, 23, (doi: 10.1186/s12874-023-01930-8)

Wang, Y. et al. (2023) Early-life cardiovascular risk factor trajectories and vascular aging in midlife: a 30-year prospective cohort study. Hypertension, 80, pp. 1057-1066. (doi: 10.1161/HYPERTENSIONAHA.122.20518)

Girerd, N. et al. (2023) Protein biomarkers of new-onset heart failure: insights from the Heart Omics and Ageing cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circulation: Heart Failure, 16, pp. 426-441. (doi: 10.1161/CIRCHEARTFAILURE.122.009694)

Degenaar, A., Jacobs, A., Kruger, R., Delles, C., Mischak, H., Mels, C.M.C. (2023) Cardiovascular risk and kidney function profiling using conventional and novel biomarkers in young adults: the African-PREDICT study. BMC Nephrology, 24, (doi: 10.1186/s12882-023-03100-w)

Collison, D., Copt, S., Mizukami, T., Collet, C., McLaren, R., Didagelos, M., Aetesam-ur-Rahman, M., McCartney, P., Ford, T. J., Lindsay, M., Shaukat, A., Rocchiccioli, P., Brogan, R., Watkins, S., McEntegart, M., Good, R., Robertson, K., O’Boyle, P., Davie, A., Khan, A., Hood, S., Eteiba, H., Berry, C., Oldroyd, K. G. (2023) Angina after percutaneous coronary intervention: patient and procedural predictors. Circulation: Cardiovascular Interventions, 16, (doi: 10.1161/CIRCINTERVENTIONS.122.012511)

Rotbain Curovic, V. et al. (2023) Presence of retinopathy and incident kidney and cardiovascular events in type 2 diabetes with normoalbuminuria – a post-hoc analysis of the PRIORITY randomized clinical trial. Journal of Diabetes and its Complications, 37, (doi: 10.1016/j.jdiacomp.2023.108433)

Edgar, B., Pearson, R., Kasthuri, R., Gillis, K., Geddes, C., Rostron, M., Brady, A., Hussey, K., Roditi, G., Delles, C., Kingsmore, D. (2023) The impact of renal artery stenting on therapeutic aims. Journal of Human Hypertension, 37, pp. 265-272. (doi: 10.1038/s41371-022-00785-8)

Fullerton, J., Bettencourt, C., Daniels, M., Mclean, F., Simpson, S., Smith, A., Woodling, N., Kerr, F. (2023) Creating connections: developing an online space for cross-regional mentorship and network building in the dementia research field. Health Open Research, 4, (doi: 10.12688/amrcopenres.13091.2)

Kimera, I. D., Namugenyi, C., Schwartz, J. I., Musimbaggo, D. J., Ssenyonjo, R., Atukunda, P., Mutungi, G., Mugabe, F., Ambangira, F., Mbuliro, M., Katwesigye, R., Neupane, D., Ssinabulya, I., Semitala, F. C., Delles, C., Muddu, M. (2023) Integrated multi-month dispensing of antihypertensive and antiretroviral therapy to sustain hypertension and HIV control. Journal of Human Hypertension, 37, pp. 213-219. (doi: 10.1038/s41371-022-00655-3)

Picone, D. S., Peterson, G. M., Jackson, S. L., Campbell, N. R.C., Delles, C., Olsen, M. H., Padwal, R., Schutte, A. E., Sharman, J. E. (2023) Perceptions of pharmacists on the quality of automated blood pressure devices: a national survey. Journal of Human Hypertension, 37, pp. 235-240. (doi: 10.1038/s41371-022-00670-4)

de Beer, D., Mels, C. M. C., Schutte, A. E., Delles, C., Mary, S., Mullen, W., Mischak, H., Kruger, R. (2023) A urinary peptidomics approach for early stages of cardiovascular disease risk: the African-PREDICT study. Hypertension Research, 46, pp. 485-494. (doi: 10.1038/s41440-022-01097-7)

Boden, W. E., Marzilli, M., Crea, F., Mancini, G.B. J., Weintraub, W. S., Taqueti, V. R., Pepine, C. J., Escaned, J., Al-Lamee, R., Gowdak, L. H. W., Berry, C., Kaski, J. C. (2023) Evolving management paradigm for stable ischemic heart disease patients: JACC review topic of the week. Journal of the American College of Cardiology, 81, pp. 505-514. (doi: 10.1016/j.jacc.2022.08.814)

Lim, M. W.S., Setjiadi, D., Dobbin, S. J.H., Lang, N. N., Delles, C., Connelly, P. J. (2023) Nailfold video-capillaroscopy in the study of cardiovascular disease: a systematic review. Blood Pressure Monitoring, 28, pp. 24-32. (doi: 10.1097/MBP.0000000000000624)

Rushworth, L. K., Loveridge, C., Salji, M., MacLeod, M., Mui, E., Sumpton, D., Neilson, M., Hedley, A., Alexander, L., McCartney, E., Patel, R., Wallace, J., Delles, C., Jones, R., Leung, H. Y. (2023) Phase II proof of concept study of atorvastatin in castration resistant prostate cancer. BJU International, 131, pp. 236-243. (doi: 10.1111/bju.15851)

Chen, J. Y., Chew, K. S., Mary, S., Boder, P., Bagordo, D., Rossi, G. P., Touyz, R. M., Delles, C., Rossitto, G. (2023) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137, pp. 239-250. (doi: 10.1042/CS20220609)

Sharman, J. E., Ordunez, P., Brady, T., Parati, G., Stergiou, G., Whelton, P. K., Padwal, R., Olsen, M. H., Delles, C., Schutte, A. E., Tomaszewski, M., Lackland, D. T., Khan, N., McManus, R. J., Tsuyuki, R. T., Zhang, X.-H., Murphy, L. D., Moran, A. E., Schlaich, M. P., Campbell, N. R.C. (2023) The urgency to regulate validation of automated blood pressure measuring devices: a policy statement and call to action from the world hypertension league. Journal of Human Hypertension, 37, pp. 155-159. (doi: 10.1038/s41371-022-00747-0)

Artico, J. et al. (2023) Myocardial involvement after hospitalization for COVID-19 complicated by troponin elevation: a prospective, multicenter, observational study. Circulation, 147, pp. 364-374. (doi: 10.1161/CIRCULATIONAHA.122.060632)

Sykes, R. et al. (2023) Rationale and design of the effect of mineralocorticoid receptor antagonist therapy in patients with acute myocardial infarction or injury and non-obstructive coronary arteries: A registry-based, stratified-medicine, randomised, controlled trial. (doi: 10.1136/heartjnl-2022-BSCMR.26)

Sattar, N., Deanfield, J., Delles, C. (2023) Impact of intentional weight loss in cardiometabolic disease: what we know about timing of benefits on differing outcomes? Cardiovascular Research, (doi: 10.1093/cvr/cvac186)

Gulati, M., Khan, N., George, M., Berry, C., Chieffo, A., Camici, P. G., Crea, F., Kaski, J.-C., Marzilli, M., Merz, C. N. B. (2023) Ischemia with no obstructive coronary artery disease (INOCA): a patient self-report quality of life survey from INOCA international. International Journal of Cardiology, 371, pp. 28-39. (doi: 10.1016/j.ijcard.2022.09.047)

Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10, (doi: 10.1136/openhrt-2022-002192)

Perera, D., Berry, C., Hoole, S. P., Sinha, A., Rahman, H., Morris, P. D., Kharbanda, R. K., Petraco, R., Channon, K. (2023) Invasive coronary physiology in patients with angina and non-obstructive coronary artery disease: a consensus document from the coronary microvascular dysfunction workstream of the British Heart Foundation/National Institute for Health Research Partnership. Heart, 109, pp. 88-95. (doi: 10.1136/heartjnl-2021-320718)

Everett, C. C., Berry, C., McCann, G. P., Fernandez, C., Reynolds, C., Bucciarelli-Ducci, C., Dall’Armellina, E., Prasad, A., Foley, J. R., Mangion, K., Bijsterveld, P., Brown, J., Stocken, D., Walker, S., Sculpher, M., Plein, S., Greenwood, J. P. (2023) Randomised trial of stable chest pain investigation: 3-year clinical and quality of life results from CE-MARC 2. Open Heart, 10, (doi: 10.1136/openhrt-2022-002221)

Hlatky, M. A., Wilding, S., Stuart, B., Nicholas, Z., Shambrook, J., Eminton, Z., Fox, K., Connolly, D., O’Kane, P., Hobson, A., Chauhan, A., Uren, N., Mccann, G. P., Berry, C., Carter, J., Roobottom, C., Mamas, M., Rajani, R., Ford, I., Douglas, P. S., Curzen, N. (2023) Randomized comparison of chest pain evaluation with FFRCT or standard care: factors determining US costs. Journal of Cardiovascular Computed Tomography, 17, pp. 52-59. (doi: 10.1016/j.jcct.2022.09.005)

Mizani, M. A., Dashtban, A., Pasea, L., Lai, A. G., Thygesen, J., Tomlinson, C., Handy, A., Mamza, J. B., Morris, T., Khalid, S., Zaccardi, F., Macleod, M. J., Torabi, F., Canoy, D., Akbari, A., Berry, C., Bolton, T., Nolan, J., Khunti, K., Denaxas, S., Hemingway, H., Sudlow, C., Banerjee, A. (2023) Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19–a data-driven retrospective cohort study. Journal of the Royal Society of Medicine, 116, pp. 10-20. (doi: 10.1177/01410768221131897)

Kulkarni, S., Glover, M., Kapil, V., Abrams, S. M. L., Partridge, S., McCormack, T., Sever, P., Delles, C., Wilkinson, I. B. (2023) Management of hypertensive crisis: British and Irish Hypertension Society position document. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00776-9)

2022

Collet, C., Collison, D., Mizukami, T., McCartney, P., Sonck, J., Ford, T., Munhoz, D., Berry, C., De Bruyne, B., Oldroyd, K. (2022) Differential improvement in angina and health-related quality of life after PCI in focal and diffuse coronary artery disease. JACC: Cardiovascular Interventions, 15, pp. 2506-2518. (doi: 10.1016/j.jcin.2022.09.048)

Murray, E. C., Delles, C., Orzechowski, P., Renc, P., Sitek, A., Wagenaar, J., Guzik, T. J. (2022) Vascular phenotypes in early hypertension. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00794-7)

Gerganova, G., Riddell, A., Miller, A. A. (2022) CNS border-associated macrophages in the homeostatic and ischaemic brain. Pharmacology and Therapeutics, 240, (doi: 10.1016/j.pharmthera.2022.108220)

Rossitto, G., Delles, C. (2022) Mechanisms of sodium-mediated injury in cardiovascular disease: old play, new scripts. FEBS Journal, 289, pp. 7260-7273. (doi: 10.1111/febs.16155)

Suda, A., Takahashi, J., Schwidder, M., Ong, P., Ang, D., Berry, C., Camici, P. G., Crea, F., Carlos Kaski, J., Pepine, C., Rimoldi, O., Sechtem, U., Yasuda, S., Beltrame, J. F., Noel Bairey Merz, C., Shimokawa, H., Coronary Vasomotor Disorders International Study COVADIS Group, . (2022) Prognostic association of plasma NT-proBNP levels in patients with microvascular angina -A report from the international cohort study by COVADIS- International Journal of Cardiology: Heart and Vasculature, 43, (doi: 10.1016/j.ijcha.2022.101139)

Bradley, C., Berry, C. (2022) Retinal microvascular function: a tractable biomarker of cardiovascular risk? Cardiovascular Research, 118, pp. 3169-3170. (doi: 10.1093/cvr/cvac170)

Kumar, A. A., Yeo, N., Whittaker, M., Attra, P., Barrick, T. R., Bridges, L. R., Dickson, D. W., Esiri, M. M., Farris, C. W., Graham, D., Lin, W. L., Meijles, D. N., Pereira, A. C., Perry, G., Rosene, D. L., Shtaya, A. B., Van Agtmael, T., Zamboni, G., Hainsworth, A. H. (2022) Vascular collagen type-IV in hypertension and cerebral small vessel disease. Stroke, 53, pp. 3696-3705. (doi: 10.1161/STROKEAHA.122.037761)

McErlane, J., McCall, P., Willder, J., Berry, C., Shelley, B. (2022) Right ventricular free wall longitudinal strain is independently associated with mortality in mechanically ventilated patients with COVID-19. Annals of Intensive Care, 12, (doi: 10.1186/s13613-022-01077-7)

Paterson, C., Hinterberg, M. A., Morrow, A. J., Sykes, R., Mangion, K., Welsh, P., McConnachie, A., Sattar, N., Berry, C., Williams, S. A. (2022) Utility of a Proteomic Surrogate for Cardiovascular Outcomes to Predict and Monitor COVID-19 Induced Myocarditis. (doi: 10.1161/circ.146.suppl_1.12132)

Yang, Y., Gao, H., Berry, C., Carrick, D., Radjenovic, A., Husmeier, D. (2022) Classification of myocardial blood flow based on dynamic contrast-enhanced magnetic resonance imaging using hierarchical Bayesian models. Journal of the Royal Statistical Society: Series C (Applied Statistics), 71, pp. 1085-1115. (doi: 10.1111/rssc.12568)

Morris, P. D., Al-Lamee, R. K., Berry, C., on behalf of the BCIS Research and Development Committee, (2022) Coronary physiological assessment in the catheter laboratory: haemodynamics, clinical assessment and future perspectives. Heart, 108, pp. 1737-1746. (doi: 10.1136/heartjnl-2020-318743)

Mary, S., Boder, P., Padmanabhan, S., McBride, M. W., Graham, D., Delles, C., Dominiczak, A. F. (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888)

Ford, T. J., Adamson, C., Morrow, A. J., Rocchiccioli, P., Collison, D., McCartney, P. J., Shaukat, A., Lindsay, M., Good, R., Watkins, S., Eteiba, H., Robertson, K., Berry, C., Oldroyd, K. G., McEntegart, M. (2022) Coronary artery perforations: Glasgow Natural History Study of Covered Stent Coronary Interventions (GNOCCI) Study. Journal of the American Heart Association, 11, (doi: 10.1161/JAHA.121.024492)

Reel, P. S. et al. (2022) Machine learning for classification of hypertension subtypes using multi-omics: a multi-centre, retrospective, data-driven study. EBioMedicine, 84, (doi: 10.1016/j.ebiom.2022.104276)

Berry, C., Morrow, A. J., Marzilli, M., Pepine, C. J. (2022) What is the role of assessing ischemia to optimize therapy and outcomes for patients with stable angina and non-obstructed coronary arteries? Cardiovascular Drugs and Therapy, 36, pp. 1027-1038. (doi: 10.1007/s10557-021-07179-x)

McQueen, A., Escuer, J., Schmidt, A. F., Aggarwal, A., Kennedy, S., McCormick, C., Oldroyd, K., Mcginty, S. (2022) An intricate interplay between stent drug dose and release rate dictates arterial restenosis. Journal of Controlled Release, 349, pp. 992-1008. (doi: 10.1016/j.jconrel.2022.07.037)

Stables, R. H. et al. (2022) Routine pressure wire assessment versus conventional angiography in the management of patients with coronary artery disease: the RIPCORD 2 trial. Circulation, 146, pp. 687-698. (doi: 10.1161/CIRCULATIONAHA.121.057793)

Daly, C., Briddon, S. (2022) Pharmacology in the Metaverse. Pharmacology Matters, 2022,

Mangion, K., Berry, C. (2022) Multisystem involvement in COVID-19: what have we learnt? British Journal of Hospital Medicine, 83, pp. 1-5. (doi: 10.12968/hmed.2022.0290)

Bradley, C., Berry, C. (2022) Definition and epidemiology of coronary microvascular disease. Journal of Nuclear Cardiology, 29, pp. 1763-1775. (doi: 10.1007/s12350-022-02974-x)

Yang, Y., Gao, H., Berry, C., Radjenovic, A., Husmeier, D. (2022) Myocardial Perfusion Classification Using A Markov Random Field Constrained Gaussian Mixture Model. (doi: 10.11159/icsta22.146)

Lee, M. M.Y. et al. (2022) Effect of empagliflozin on kidney biochemical and imaging outcomes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 146, pp. 364-367. (doi: 10.1161/CIRCULATIONAHA.122.059851)

Ferreira, V. M., Berry, C. (2022) The health economics of ischemia with nonobstructive coronary arteries. JACC: Cardiovascular Imaging, 14, pp. 1380-1383. (doi: 10.1016/j.jcmg.2021.03.017)

Bularga, A. et al. (2022) Assessment of oxygen supply-demand imbalance and outcomes among patients with type 2 myocardial infarction: a secondary analysis of the High-STEACS cluster randomized clinical trial. JAMA Network Open, 5, (doi: 10.1001/jamanetworkopen.2022.20162)

Ang, D., Berry, C. (2022) FAVOR III China: quantitative flow ratio-guided coronary intervention in practice. Cardiovascular Research, 118, pp. e78-e80. (doi: 10.1093/cvr/cvac109)

Gallacher, P. J. et al. (2022) High-sensitivity cardiac troponin and the diagnosis of myocardial infarction in patients with renal impairment. Kidney International, 102, pp. 149-159. (doi: 10.1016/j.kint.2022.02.019)

Houchen-Wolloff, L. et al. (2022) Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19. Thorax, 77, pp. 717-720. (doi: 10.1136/thoraxjnl-2021-218582)

McCall, P.J., Willder, J.M., Stanley, B.L., Messow, C.-M., Allan, J., Gemmell, L., Puxty, A., Strachan, D., Berry, C., Shelley, B.G. (2022) Right ventricular dysfunction in patients with COVID-19 pneumonitis whose lungs are mechanically ventilated: a multicentre prospective cohort study. Anaesthesia, 77, pp. 772-784. (doi: 10.1111/anae.15745)

Lip, S., McCallum, L., Delles, C., McClure, J. D., Guzik, T., Berry, C., Touyz, R., Padmanabhan, S. (2022) Rationale and design for the LOnger-term effects of SARS-CoV-2 INfection on blood Vessels And blood pRessure (LOCHINVAR) Open Heart, 9, (doi: 10.1136/openhrt-2022-002057)

Mangion, K. et al. (2022) Multi-system investigation of COVID-19 illness. (doi: 10.1136/heartjnl-2022-BCS.157)

Morrow, A. J. et al. (2022) A multisystem, cardio-renal investigation of post-COVID-19 illness. Nature Medicine, 28, pp. 1303-1313. (doi: 10.1038/s41591-022-01837-9)

Craig, A., Delles, C., Murray, E. C. (2022) A review of vascular traits and assessment techniques, and their heritability. Artery Research, 28, pp. 61-78. (doi: 10.1007/s44200-022-00016-y)

Schwartze, J. T., Havenga, M., Bakker, W. A. M., Bradshaw, A. C., Nicklin, S. A. (2022) Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective. Journal of Molecular Medicine, 100, pp. 875-901. (doi: 10.1007/s00109-022-02208-0)

Wang, Y. et al. (2022) Associations of long-term visit-to-visit blood pressure variability with subclinical kidney damage and albuminuria in adulthood: a 30-year prospective cohort study. Hypertension, 79, pp. 1247-1256. (doi: 10.1161/HYPERTENSIONAHA.121.18658)

Lucas-Herald, A. K., Delles, C. (2022) Carotid intima-media thickness is associated with obesity and hypertension in young people. Hypertension, 79, pp. 1177-1179. (doi: 10.1161/hypertensionaha.122.19163)

Rastogi, T., Ho, F. K., Rossignol, P., Merkling, T., Butler, J., Clark, A., Collier, T., Delles, C., Jukema, J. W., Heymans, S., Latini, R., Mebazaa, A., Pellicori, P., Sever, P., Staessen, J. A., Thijs, L., Cleland, J. G., Sattar, N., Zannad, F., Girerd, N. (2022) Comparing and contrasting risk factors for heart failure in patients with and without history of myocardial infarction: data from HOMAGE and the UK Biobank. European Journal of Heart Failure, 24, pp. 976-984. (doi: 10.1002/ejhf.2495)

Berry, C., Sykes, R. (2022) Microvascular dysfunction in heart failure with preserved ejection fraction: a modifiable therapeutic target? JACC: Cardiovascular Imaging, 15, pp. 1012-1014. (doi: 10.1016/j.jcmg.2022.04.008)

Connelly, P. J., Currie, G., Delles, C. (2022) Sex differences in the prevalence, outcomes and management of hypertension. Current Hypertension Reports, 24, pp. 185-192. (doi: 10.1007/s11906-022-01183-8)

Fullerton, J. L., Thomas, J. M., Gonzalez-Trueba, L., Trivett, C., Van Kralingen, J. C., Allan, S. M., Quinn, T. J., Work, L. M. (2022) Systematic review: association between circulating microRNA expression & stroke. Journal of Cerebral Blood Flow and Metabolism, 42, pp. 935-951. (doi: 10.1177/0271678X221085090)

Crea, F., Badimon, L., Berry, C., De Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C., Tybjaerg-Hansen on behalf of the EHJ Editorial Board, A. (2022) The European Heart Journal: fulfilling the mission. European Heart Journal, 43, pp. 2181-2184. (doi: 10.1093/eurheartj/ehac171)

Lucas-Herald, A. K., Montezano, A. C., Alves-Lopes, R., Haddow, L., Alimussina, M., O’Toole, S., Flett, M., Lee, B., Amjad, S. B., Steven, M., Brooksbank, K., McCallum, L., Delles, C., Padmanabhan, S., Ahmed, S. F., Touyz, R. M. (2022) Vascular dysfunction and increased cardiovascular risk in hypospadias. European Heart Journal, 43, pp. 1832-1845. (doi: 10.1093/eurheartj/ehac112)

Rossitto, G., Delles, C. (2022) Does excess tissue sodium storage regulate blood pressure? Current Hypertension Reports, 24, pp. 115-122. (doi: 10.1007/s11906-022-01180-x)

He, W. et al. (2022) Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size. Cardiovascular Research, 118, pp. 1535-1547. (doi: 10.1093/cvr/cvab204)

Al-Lamee, R., Aubiniere-Robb, L., Berry, C. (2022) The British Cardiovascular Society and clinical studies in ischaemic heart disease: from RITA to ORBITA, and beyond. Heart, 108, pp. 800-806. (doi: 10.1136/heartjnl-2021-320150)

Kite, T. A., Banning, A. S., Ladwiniec, A., Gale, C. P., Greenwood, J. P., Dalby, M., Hobson, R., Barber, S., Parker, E., Berry, C., Flather, M. D., Curzen, N., Banning, A. P., McCann, G. P., Gershlick, A. H. (2022) Very early invasive angiography versus standard of care in higher-risk non-ST elevation myocardial infarction: study protocol for the prospective multicentre randomised controlled RAPID N-STEMI trial. BMJ Open, 12, (doi: 10.1136/bmjopen-2021-055878)

Maurovich-Horvat, P. et al. (2022) CT or invasive coronary angiography in stable chest pain. New England Journal of Medicine, 386, pp. 1591-1602. (doi: 10.1056/NEJMoa2200963)

Malfait, F., Forlino, A., Sengle, G., Van Agtmael, T. (2022) Editorial: molecular mechanisms of heritable connective tissue disorders. Frontiers in Genetics, 13, (doi: 10.3389/fgene.2022.866665)

Berry, C., Ang, D. T.Y. (2022) Picture perfect? Performance of quantitative coronary angiography-based vessel FFR versus pressure wire-based FFR. EuroIntervention, 17, pp. 1463-1465. (doi: 10.4244/EIJ-E-22-00005)

Sani, R. N., Connelly, P. J., Toft, M., Rowa-Dewar, N., Delles, C., Gasevic, D., Karaye, K. M. (2022) Rural-urban difference in the prevalence of hypertension in West Africa: a systematic review and meta-analysis. Journal of Human Hypertension, (doi: 10.1038/s41371-022-00688-8)

Fullerton, J. L., Cosgrove, C. C., Rooney, R. A., Work, L. (2022) Extracellular vesicles and their microRNA cargo in ischaemic stroke. Journal of Physiology, (doi: 10.1113/JP282050)

Mileva, N., Nagumo, S., Mizukami, T., Sonck, J., Berry, C., Gallinoro, E., Monizzi, G., Candreva, A., Munhoz, D., Vassilev, D., Penicka, M., Barbato, E., De Bruyne, B., Collet, C. (2022) Prevalence of coronary microvascular disease and coronary vasospasm in patients with nonobstructive coronary artery disease: systematic review and meta‐analysis. Journal of the American Heart Association, 11, (doi: 10.1161/JAHA.121.023207)

Toloza, F. J. K. et al. (2022) Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. Lancet Diabetes and Endocrinology, 10, pp. 243-252. (doi: 10.1016/S2213-8587(22)00007-9)

Abraham, G. R., Morrow, A. J., Oliveira, J., Weir-McCall, J. R., Davenport, E. E., Berry, C., Davenport, A. P., Hoole, S. P. (2022) Mechanistic study of the effect of Endothelin SNPs in microvascular angina – Protocol of the PRIZE Endothelin Sub-Study. International Journal of Cardiology: Heart and Vasculature, 39, (doi: 10.1016/j.ijcha.2022.100980)

Ang, D. T.Y., Sidik, N. P., Morrow, A. J., Sykes, R., McEntegart, M. B., Berry, C. (2022) Interventional diagnostic procedure: A practical guide for the assessment of coronary vascular function. Journal of Visualized Experiments, 181, (doi: 10.3791/62265)

Divorty, N., Jenkins, L., Ganguly, A., Butcher, A. J., Hudson, B. D., Schulz, S., Tobin, A. B., Nicklin, S. A., Milligan, G. (2022) Agonist-induced phosphorylation of orthologues of the orphan receptor GPR35 functions as an activation sensor. Journal of Biological Chemistry, 298, (doi: 10.1016/j.jbc.2022.101655)

Martin, T. P., MacDonald, E. A., Elbassioni, A. A., Zaeri, A. A. I., O'Toole, D., Nicklin, S. A., Gray, G. A., Loughrey, C. M. (2022) Pre-clinical models of myocardial infarction: from mechanism to translation. British Journal of Pharmacology, 179, pp. 770-791. (doi: 10.1111/bph.15595)

Reynolds, H. R., Bairey Merz, C. N., Berry, C., Samuel, R., Saw, J., Smilowitz, N. R., de Souza, A. C. d. A.H., Sykes, R., Taqueti, V. R., Wei, J. (2022) Coronary arterial function and disease in women with no obstructive coronary arteries. Circulation Research, 130, pp. 529-551. (doi: 10.1161/CIRCRESAHA.121.319892)

Mujaj, B., ZHang, Z.-Y., Yang, W.-Y., Thijs, L., Wei, F.-F., Verhamme, P., Delles, C., Butler, J., Sever, P., Latini, R., Cleland, J. G. F., Zannad, F., Staessen, J. A. (2022) Aspirin use is associated with increased risk for incident heart failure: a patient-level pooled analysis. ESC Heart Failure, 9, pp. 685-694. (doi: 10.1002/ehf2.13688)

Bakalchuk, S., Walker, C., Daly, C., Hill, L., Poyade, M. (2022) Creating interactive three-dimensional applications to visualise novel stent grafts that aid in the treatment of aortic aneurysms. Springer

Connelly, P. J., Casey, H., Montezano, A. C., Touyz, R. M., Delles, C. (2022) Sex steroids receptors, hypertension and vascular ageing. Journal of Human Hypertension, 36, pp. 120-125. (doi: 10.1038/s41371-021-00576-7)

Douglass, A., Moffat, G., Daly, C. (2022) Using confocal microscopy to generate an accurate vascular model for use in patient education animation. Springer

Delles, C. (2022) Maternally inherited essential hypertension: adding further complexity to an already complex condition. American Journal of Hypertension, 35, pp. 16-18. (doi: 10.1093/ajh/hpab133)

Delles, C., Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water. Function, 3, (doi: 10.1093/function/zqab071)

Morrow, A., Gray, S. R., Bayes, H. K., Sykes, R., McGarry, E., Anderson, D., Boiskin, D., Burke, C., Cleland, J. G. F., Goodyear, C., Ibbotson, T., Lang, C. C., McConnachie, A., Mair, F., Mangion, K., Patel, M., Sattar, N., Taggart, D., Taylor, R., Dawkes, S., Berry, C. (2022) Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise—CISCO-21. Trials, 23, (doi: 10.1186/s13063-022-06632-y)

2021

Connelly, P. J., Delles, C. (2021) Cardiovascular disease in transgender people: recent research and emerging evidence. Cardiovascular Research, 117, pp. e174-e176. (doi: 10.1093/cvr/cvab288)

Collison, D., Didagelos, M., Aetesam-Ur-Rahman, M., Copt, S., McDade, R., McCartney, P., Ford, T. J., McClure, J., Lindsay, M., Shaukat, A., Rocchiccioli, P., Brogan, R., Watkins, S., McEntegart, M., Good, R., Robertson, K., O’Boyle, P., Davie, A., Khan, A., Hood, S., Eteiba, H., Berry, C., Oldroyd, K. G. (2021) Post-stenting fractional flow reserve vs coronary angiography for optimization of percutaneous coronary intervention (TARGET-FFR) European Heart Journal, 42, pp. 4656-4668. (doi: 10.1093/eurheartj/ehab449)

Omar, R., Malfait, F., Van Agtmael, T. (2021) Four decades in the making: collagen III and mechanisms of vascular Ehlers Danlos Syndrome. Matrix Biology Plus, 12, (doi: 10.1016/j.mbplus.2021.100090)

Alsufyani, H. A., Daly, C., Docherty, J. R. (2021) Interaction between α 1B ‐ and other α 1 ‐ and α 2 ‐adrenoceptors in producing contractions of mouse spleen. Basic and Clinical Pharmacology and Toxicology, 129, pp. 416-426. (doi: 10.1111/bcpt.13639)

Keenan, N. G., Captur, G., McCann, G. P., Berry, C., Myerson, S. G., Fairbairn, T., Hudsmith, L., O'Regan, D. P., Westwood, M., Greenwood, J. P. (2021) Regional variation in cardiovascular magnetic resonance service delivery across the UK. Heart, 107, pp. 1974-1979. (doi: 10.1136/heartjnl-2020-318667)

Mary, S., Boder, P., Rossitto, G., Graham, L., Scott, K., Flynn, A., Kipgen, D., Graham, D., Delles, C. (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135, pp. 2749-2761. (doi: 10.1042/CS20211017)

Rankin, A. J., Mangion, K., Lees, J. S., Rutherford, E., Gillis, K. A., Edy, E., Dymock, L., Treibel, T. A., Radjenovic, A., Patel, R. K., Berry, C., Roditi, G., Mark, P. B. (2021) Myocardial changes on 3T cardiovascular magnetic resonance imaging in response to haemodialysis with fluid removal. Journal of Cardiovascular Magnetic Resonance, 23, (doi: 10.1186/s12968-021-00822-4)

Berry, C. et al. (2021) Post-COVID-19 illness trajectory: a multisystem investigation [Pre-print] Research Square, (doi: 10.21203/rs.3.rs-1053331/v1)

van Vliet, N. A. et al. (2021) Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling. BMC Medicine, 19, (doi: 10.1186/s12916-021-02130-1)

Morrow, A. et al. (2021) Rationale and design of the Medical Research Council Precision medicine with Zibotentan in microvascular angina (PRIZE) trial MRI sub-study. (doi: 10.1136/heartjnl-2021-BSCMR.3)

MacKenzie, S. M., Saunders, H., van Kralingen, J. C., Robertson, S., Riddell, A., Zennaro, M.-C., Davies, E. (2021) Circulating microRNAs as diagnostic markers in primary aldosteronism. Cancers, 13, (doi: 10.3390/cancers13215312)

He, T. et al. (2021) Urinary peptides in heart failure: a link to molecular pathophysiology. European Journal of Heart Failure, 23, pp. 1875-1887. (doi: 10.1002/ejhf.2195)

Shoaib, A., Rashid, M., Berry, C., Curzen, N., Kontopantelis, E., Timmis, A., Ahmad, A., Kinnaird, T., Mamas, M. A. (2021) Clinical characteristics, management strategies, and outcomes of non–ST‐segment–elevation myocardial infarction patients with and without prior coronary artery bypass grafting. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.120.018823)

Curzen, N. et al. (2021) Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial. European Heart Journal, 42, pp. 3844-3852. (doi: 10.1093/eurheartj/ehab444)

Touyz, R. M., Boyd, M. O.E., Guzik, T., Padmanabhan, S., McCallum, L., Delles, C., Mark, P. B., Petrie, J. R., Rios, F., Montezano, A. C., Sykes, R., Berry, C. (2021) Cardiovascular and renal risk factors and complications associated with COVID-19. CJC Open, 3, pp. 1257-1272. (doi: 10.1016/j.cjco.2021.05.020)

Rankin, A. J., Zhu, L., Mangion, K., Rutherford, E., Gillis, K. A., Lees, J. S., Woodward, R., Patel, R. K., Berry, C., Roditi, G., Mark, P. B. (2021) Global longitudinal strain by feature tracking cardiovascular MRI predicts mortality in patients with end stage kidney disease. Clinical Kidney Journal, 14, pp. 2187-2196. (doi: 10.1093/ckj/sfab020)

Raafs, A. et al. (2021) Identification of sex‐specific biomarkers predicting new‐onset heart failure. ESC Heart Failure, 8, pp. 3512-3520. (doi: 10.1002/ehf2.13476)

Rush, C. J., Berry, C., Oldroyd, K. G., Rocchiccioli, J. P., Lindsay, M. M., Touyz, R. M., Murphy, C. L., Ford, T. J., Sidik, N., McEntegart, M. B., Lang, N. N., Jhund, P. S., Campbell, R. T., McMurray, J. J.V., Petrie, M. C. (2021) Prevalence of coronary artery disease and coronary microvascular dysfunction in patients with heart failure with preserved ejection fraction. JAMA Cardiology, 6, pp. 1130-1143. (doi: 10.1001/jamacardio.2021.1825)

Anderson, J. J., Ho, F. K., Niedzwiedz, C. L., Katikireddi, V., Celis-Morales, C., Iliodromiti, S., Welsh, P., Pellicori, P., Demou, E., Hastie, C. E., Lyall, D. M., Gray, S. R., Forbes, J. F., Gill, J. M.R., Mackay, D. F., Berry, C., Cleland, J. G.F., Sattar, N., Pell, J. P. (2021) Remote history of VTE is associated with severe COVID-19 in middle and older age: UK Biobank cohort study. Journal of Thrombosis and Haemostasis, 19, pp. 2533-2538. (doi: 10.1111/jth.15452)

Ho, F. K., Man, K. K.S., Toshner, M., Church, C., Celis-Morales, C., Wong, I. C.K., Berry, C., Sattar, N., Pell, J. P. (2021) Thromboembolic risk in hospitalised and non-hospitalised Covid-19 patients: a self-controlled case series analysis of a nation-wide cohort. Mayo Clinic Proceedings, 96, pp. 2587-2597. (doi: 10.1016/j.mayocp.2021.07.002)

Pokhilko, A., Brezzo, G., Handunnetthi, L., Heilig, R., Lennon, R., Smith, C., Allan, S. M., Granata, A., Sinha, S., Wang, T., Markus, H. S., Naba, A., Fischer, R., Van Agtmael, T., Horsburgh, K., Cader, M. Z. (2021) Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease. Journal of Cerebral Blood Flow and Metabolism, 41, pp. 2423-2438. (doi: 10.1177/0271678X211004307)

Docherty, N. G., Delles, C., D’Haese, P., Layton, A. T., Martínez-Salgado, C., Vervaet, B. A., López-Hernández, F. J. (2021) Haemodynamic frailty – A risk factor for acute kidney injury in the elderly. Ageing Research Reviews, 70, (doi: 10.1016/j.arr.2021.101408)

Sigfrid, L. et al. (2021) Long Covid in adults discharged from UK hospitals after Covid-19: a prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol. Lancet Regional Health - Europe, 8, (doi: 10.1016/j.lanepe.2021.100186)

Romaszko, L., Borowska, A., Lazarus, A., Dalton, D., Berry, C., Luo, X., Husmeier, D., Gao, H. (2021) Neural network-based left ventricle geometry prediction from CMR images with application in biomechanics. Artificial Intelligence In Medicine, 119, (doi: 10.1016/j.artmed.2021.102140)

Alves-Lopes, R., Montezano, A. C., Neves, K. B., Harvey, A., Rios, F. J., Skiba, D. S., Arendse, L. B., Guzik, T. J., Graham, D., Poglitsch, M., Sturrock, E., Touyz, R. M. (2021) Selective inhibition of the C-domain of ACE (angiotensin-converting enzyme) combined with inhibition of NEP (neprilysin): a potential new therapy for hypertension. Hypertension, 78, pp. 604-616. (doi: 10.1161/HYPERTENSIONAHA.121.17041)

Heggie, R., Briggs, A., Stanley, B., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., YII, E., Collison, D., Oldroyd, K., Ford, T. J., Berry, C. (2021) Stratified medicine using invasive coronary function testing in angina: a cost-effectiveness analysis of the British Heart Foundation CorMicA trial. International Journal of Cardiology, 337, pp. 44-51. (doi: 10.1016/j.ijcard.2021.05.016)

Boder, P., Mary, S., Mark, P. B., Leiper, J., Dominiczak, A. F., Padmanabhan, S., Rampold, L., Delles, C. (2021) Mechanistic interactions of uromodulin with the thick ascending limb: perspectives in physiology and hypertension. Journal of Hypertension, 39, pp. 1490-1504. (doi: 10.1097/HJH.0000000000002861)

Bates, E. A., Counsell, J. R., Alizert, S., Baker, A. T., Suff, N., Boyle, A., Bradshaw, A. C., Waddington, S. N., Nicklin, S. A., Baker, A. H., Parker, A. L. (2021) In vitro and in vivo evaluation of human adenovirus type 49 as a vector for therapeutic applications. Viruses, 13, (doi: 10.3390/v13081483)

Patanapirunhakit, P., Karlsson, H., Mulder, M., Ljunggren, S., Graham, D., Freeman, D. (2021) Sphingolipids in HDL – potential markers for adaptation to pregnancy? Biochimica et Biophysica Acta: Molecular and Cell Biology of Lipids, 1866, (doi: 10.1016/j.bbalip.2021.158955)

Boland, E., Quondamatteo, F., Van Agtmael, T. (2021) The role of basement membranes in cardiac biology and disease. Bioscience Reports, 41, pp. BSR20204185. (doi: 10.1042/bsr20204185)

Chung, J. et al. (2021) Rare missense functional variants at COL4A1 and COL4A2 in sporadic intracerebral hemorrhage. Neurology, 97, pp. e236-e247. (doi: 10.1212/WNL.0000000000012227)

Randles, M., Lausecker, F., Kong, Q., Suleiman, H., Reid, G., Kolatsi-Joannou, M., Tian, P., Falcone, S., Davenport, B., Potter, P., Van Agtmael, T., Norman, J., Long, D., Humphries, M., Miner, J., Lennon, R. (2021) Identification of an altered matrix signature in kidney aging and disease. Journal of the American Society of Nephrology, 32, pp. 1713-1732. (doi: 10.1681/ASN.2020101442)

Anand, A., Lee, K. K., Chapman, A. R., Ferry, A. V., Adamson, P. D., Strachan, F. E., Berry, C., Findlay, I., Cruikshank, A., Reid, A., Collinson, P. O., Apple, F. S., McAllister, D., Maguire, D., Fox, K. A.A., Newby, D. E., Tuck, C., Harkess, R., Keerie, C., Weir, C. J., Parker, R. A., Gray, A., Shah, A. S.V., Mills, N. (2021) High-sensitivity cardiac troponin on presentation to rule out myocardial infarction: a stepped-wedge cluster randomized controlled trial. Circulation, 143, pp. 2214-2224. (doi: 10.1161/CIRCULATIONAHA.120.052380)

Reuten, R. et al. (2021) Basement membrane stiffness determines metastases formation. Nature Materials, 20, pp. 892-903. (doi: 10.1038/s41563-020-00894-0)

Murray, E., Rossitto, G., Delles, C. (2021) Haemodynamic assessment in hypertension: the soloists and the orchestra. Journal of Hypertension, 39, pp. 1109-1111. (doi: 10.1097/HJH.0000000000002796)

Mary, S., Small, H., Herse, F., Carrick, E., Flynn, A., Mullen, W., Dechend, R., Delles, C. (2021) Pre-existing hypertension and pregnancy induced hypertension reveal molecular differences in placental proteome in rodents. Physiological Genomics, 53, pp. 259-268. (doi: 10.1152/physiolgenomics.00160.2020)

Maznyczka, A. M., Carrick, D., Oldroyd, K. G., James-Rae, G., McCartney, P., Greenwood, J. P., Good, R., McEntegart, M., Eteiba, H., Lindsay, M., Cotton, J. M., Petrie, M. C., Berry, C. (2021) Thermodilution-derived temperature recovery time, a novel predictor of microvascular reperfusion and prognosis after myocardial infarction. EuroIntervention, 17, pp. 220-228. (doi: 10.4244/EIJ-D-19-00904)

Alshuhri, M. S., Gallagher, L., Work, L., Holmes, W. (2021) Direct imaging of glymphatic flow using H217O MRI. JCI Insight, 6, (doi: 10.1172/jci.insight.141159)

McQueen, A., Escuer, J., Aggarwal, A., Kennedy, S., McCormick, C., Oldroyd, K., Mcginty, S. (2021) Do we really understand how drug eluted from stents modulates arterial healing? International Journal of Pharmaceutics, 601, (doi: 10.1016/j.ijpharm.2021.120575)

Rossitto, G., Maiolino, G., Lerco, S., Ceolotto, G., Blackburn, G., Mary, S., Antonelli, G., Berton, C., Bisogni, V., Cesari, M., Seccia, T. M., Lenzini, L., Pinato, A., Montezano, A., Touyz, R. M., Petrie, M. C., Daly, R., Welsh, P., Plebani, M., Rossi, G. P., Delles, C. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117, pp. 1372-1381. (doi: 10.1093/cvr/cvaa205)

Heath Richardson, S. I., Gao, H., Cox, J., Janiczek, R., Griffith, B. E., Berry, C., Luo, X. (2021) A poroelastic immersed finite element framework for modeling cardiac perfusion and fluid-structure interaction. International Journal for Numerical Methods in Biomedical Engineering, 37, (doi: 10.1002/cnm.3446)

Schofield, C. L., Rodrigo-Navarro, A., Dalby, M. J., Van Agtmael, T., Salmeron-Sanchez, M. (2021) Biochemical­­– and biophysical–induced barriergenesis in the blood brain barrier: a review of barriergenic factors for use in in vitro models. Advanced NanoBiomed Research, 1, (doi: 10.1002/anbr.202000068)

Dean, A., Van Agtmael, T. (2021) Collagen IV-related diseases and therapies. Springer

Connelly, P. J., Azizi, Z., Alipour, P., Delles, C., Pilote, L., Raparelli, V. (2021) The importance of gender to understand sex differences in cardiovascular disease. Canadian Journal of Cardiology, 37, pp. 699-710. (doi: 10.1016/j.cjca.2021.02.005)

Vlahou, A. et al. (2021) Data sharing under the General Data Protection Regulation: time to harmonize law and research ethics? Hypertension, 77, pp. 1029-1035. (doi: 10.1161/HYPERTENSIONAHA.120.16340)

Scott, K., Morgan, H. L., Delles, C., Fisher, S., Graham, D., McBride, M. W. (2021) Distinct uterine artery gene expression profiles during early gestation in the stroke-prone spontaneously hypertensive rat. Physiological Genomics, 53, pp. 160-171. (doi: 10.1152/physiolgenomics.00159.2020)

Sigfrid, L. et al. (2021) What is the recovery rate and risk of long-term consequences following a diagnosis of COVID-19? A harmonised, global longitudinal observational study protocol. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-043887)

Pellicori, P., Doolub, G., Wong, C. M., Lee, K. S., Mangion, K., Ahmad, M., Berry, C., Squire, I., Lambiase, P., Lyon, A. R., McConnachie, A., Taylor, R. S., Cleland, J. G.F. (2021) COVID-19 and its cardiovascular effects: a systematic review of prevalence studies. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.CD013879)

Briscoe, M., Sykes, R., Krystofiak, T., Peck, O., Mangion, K., Berry, C. (2021) Clinical significance of coronavirus disease 2019 in hospitalized patients with myocardial injury. Clinical Cardiology, 44, pp. 332-339. (doi: 10.1002/clc.23530)

Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2021) Inflammation and salt in young adults: the African-PREDICT study. European Journal of Nutrition, 60, pp. 873-882. (doi: 10.1007/s00394-020-02292-3)

Sykes, R. A., Mohamed, M. O., Kwok, C. S., Mamas, M. A., Berry, C. (2021) Percutaneous coronary intervention and 30-day unplanned readmission with chest pain in the United States (nationwide readmissions database) Clinical Cardiology, 44, pp. 291-306. (doi: 10.1002/clc.23543)

Neves, K. B., Morris, H., Alves-Lopes, R., Muir, K. W., Moreton, F., Delles, C., Montezano, A. C., Touyz, R. M. (2021) Peripheral arteriopathy caused by Notch3 gain-of-function mutation involves ER and oxidative stress and blunting of NO∕sGC∕cGMP pathway. Clinical Science, 135, pp. 753-773. (doi: 10.1042/CS20201412)

Doherty, D. J., Sykes, R., Mangion, K., Berry, C. (2021) Predictors of microvascular reperfusion after myocardial infarction. Current Cardiology Reports, 23, (doi: 10.1007/s11886-021-01442-1)

Lee, M. M.Y. et al. (2021) Invasive versus medically managed acute coronary syndromes with prior bypass (CABG-ACS): insights into the registry versus randomised trial populations. Open Heart, 8, (doi: 10.1136/openhrt-2020-001453)

Lee, M. M.Y. et al. (2021) Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 143, pp. 516-525. (doi: 10.1161/CIRCULATIONAHA.120.052186)

Li, W., Gao, H., Mangion, K., Berry, C., Luo, X. (2021) Apparent growth tensor of left ventricular post myocardial infarction – in human first natural history study. Computers in Biology and Medicine, 129, (doi: 10.1016/j.compbiomed.2020.104168)

Maznyczka, A. M., McCartney, P., Duklas, P., McEntegart, M., Oldroyd, K., Greenwood, J., Muir, D., Chowdhary, S., Gershlick, A. H., Eteiba, H., Cotton, J., Wragg, A., Curzen, N., Tait, R., Macfarlane, P., Welsh, P., Sattar, N., Petrie, M., Ford, I., Fox, K., McConnachie, A., Berry, C. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107, pp. 299-312. (doi: 10.1136/heartjnl-2020-317828)

Maznyczka, A. M., McCartney, P. J., Oldroyd, K. G., Lindsay, M., McEntegart, M., Eteiba, H., Rocchiccioli, J. P., Good, R., Shaukat, A., Robertson, K., Malkin, C. J., Greenwood, J. P., Cotton, J. M., Hood, S., Watkins, S., Collison, D., Gillespie, L., Ford, T. J., Weir, R. A.P., McConnachie, A., Berry, C. (2021) Risk stratification guided by the index of microcirculatory resistance and left ventricular end-diastolic pressure in acute myocardial infarction. Circulation: Cardiovascular Interventions, 14, (doi: 10.1161/CIRCINTERVENTIONS.120.009529)

Connelly, P. J., Clark, A., Touyz, R. M., Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review. Journal of Hypertension, 39, pp. 223-230. (doi: 10.1097/HJH.0000000000002632)

Corcoran, D., Radjenovic, A., Mordi, I., Nazir, S. A., Wilson, S. J., Hinder, M., Yates, D. P., Machineni, S., Alcantara, J., Prescott, M. F., Gugliotta, B., Pang, Y., Tzemos, N., Semple, S. I., Newby, D. E., McCann, G. P., Squire, I., Berry, C. (2021) Vascular effects of serelaxin in patients with stable coronary artery disease: a randomized placebo-controlled trial. Cardiovascular Research, 117, pp. 320-329. (doi: 10.1093/cvr/cvz345)

Moreton, F. C., Cullen, B., Dickie, D. A., Lopez Gonzalez, R., Santosh, C., Delles, C., Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up. European Journal of Neurology, 28, pp. 220-228. (doi: 10.1111/ene.14534)

Willder, J. M., McCall, P., Messow, C.-M., Gillies, M., Berry, C., Shelley, B. (2021) Study protocol for COVID-RV: a multicentre prospective observational cohort study of right ventricular dysfunction in ventilated patients with COVID-19. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-042098)

Jacobs, M., Benovoy, M., Chang, L.-C., Corcoran, D., Berry, C., Arai, A. E., Hsu, L.-Y. (2021) Automated segmental analysis of fully quantitative myocardial blood flow maps by first-pass perfusion cardiovascular magnetic resonance. IEEE Access, 9, pp. 52796-52811. (doi: 10.1109/ACCESS.2021.3070320)

Kamdar, A., Sykes, R., Morrow, A., Mangion, K., Berry, C. (2021) Cardiovascular outcomes of glucose lowering therapy in chronic kidney disease patients: a systematic review with meta-analysis. Reviews in Cardiovascular Medicine, 22, pp. 1479-1490. (doi: 10.31083/j.rcm2204152)

Small, H. Y., Delles, C. (2021) Letter to the Editor regarding Cunningham et al. 2020. Hypertension in Pregnancy, 40, pp. 133. (doi: 10.1080/10641955.2021.1899201)

Sykes, R., Briscoe, M., Krystofiak, T., Peck, O., Mangion, K., Berry, C. (2021) Type 2 myocardial infarction and myocardial injury: eligibility for novel medical therapy to de-risk clinical trials. Open Heart, 8, (doi: 10.1136/openhrt-2021-001633)

Ang, D. T. Y., Berry, C. (2021) What an interventionalist needs to know about INOCA. Interventional Cardiology Review, 16, (doi: 10.15420/icr.2021.16)

Sykes, R., Doherty, D., Mangion, K., Morrow, A., Berry, C. (2021) What an interventionalist needs to know about MI with non-obstructive coronary arteries. Interventional Cardiology Review, 16, (doi: 10.15420/icr.2021.10)

2020

Abdulqader, A., Kennedy, S. (2020) The influence of perivascular adipose tissue on vascular function in a rabbit model. Pharmacology and Pharmacy, 11, pp. 331-349. (doi: 10.4236/pp.2020.1112027)

Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)

Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116, pp. 2185-2196. (doi: 10.1093/cvr/cvaa209)

Mangion, K., Loughrey, C., Auger, D. A., McComb, C., Lee, M. M., Corcoran, D., McEntegart, M., Davie, A., Good, R., Lindsay, M., Eteiba, H., Rocchiccioli, J. P., Watkins, S., Hood, S., Shaukat, A., Haig, C., Epstein, F. H., Berry, C. (2020) Displacement encoding with stimulated echoes enables the identification of infarct transmurality early postmyocardial infarction. Journal of Magnetic Resonance Imaging, 52, pp. 1722-1731. (doi: 10.1002/jmri.27295)

O'Toole, D., Zaeri, A. A. I., Nicklin, S. A., French, A. T., Loughrey, C. M., Martin, T. P. (2020) Signalling pathways linking cysteine cathepsins to adverse cardiac remodelling. Cellular Signalling, 76, (doi: 10.1016/j.cellsig.2020.109770)

McFall, A., Nicklin, S. A., Work, L. M. (2020) The counter regulatory axis of the renin angiotensin system in the brain and ischaemic stroke: insight from preclinical stroke studies and therapeutic potential. Cellular Signalling, 76, (doi: 10.1016/j.cellsig.2020.109809)

Pashova, A., Work, L.M., Nicklin, S.A. (2020) The role of extracellular vesicles in neointima formation post vascular injury. Cellular Signalling, 76, (doi: 10.1016/j.cellsig.2020.109783)

Beazer, J. D., Patanapirunhakit, P., Gill, J. M.R., Graham, D., Karlsson, H., Ljunggren, S., Mulder, M., Freeman, D. J. (2020) High-density lipoprotein’s vascular protective functions in metabolic and cardiovascular disease - could extracellular vesicles be at play? Clinical Science, 134, pp. 2977-2986. (doi: 10.1042/CS20200892)

Ho, F. K., Celis-Morales, C. A., Gray, S. R., Katikireddi, S. V., Niedzwiedz, C. L., Hastie, C., Ferguson, L. D., Berry, C., Mackay, D. F., Gill, J. M.R., Pell, J. P., Sattar, N., Welsh, P. (2020) Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study. BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040402)

Briscoe, M., Sykes, R. A., Krysztofiak, T., Peck, O. H., Mangion, K., Berry, C. (2020) Clinical Significance of Coronavirus Disease 2019 in Hospitalized Patients With Myocardial Injury. (doi: 10.1161/circ.142.suppl_3.15932)

Briscoe, M., Sykes, R. A., Krysztofiak, T., Mangion, K., Peck, O. H., Berry, C. (2020) Clinical Significance of Troponin Elevation in a Contemporary Hospitalized Population: Endotypes, Morbidity and In-hospital Mortality. (doi: 10.1161/circ.142.suppl_3.14870)

Charla, E., Mercer, J., Maffia, P., Nicklin, S. (2020) Extracellular vesicle signalling in atherosclerosis. Cellular Signalling, 75, (doi: 10.1016/j.cellsig.2020.109751)

McCartney, P. J. et al. (2020) Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT. Efficacy and Mechanism Evaluation, 7, (doi: 10.3310/eme07050)

Morrow, A. J. et al. (2020) Rationale and design of the Medical Research Council precision medicine with Zibotentan in microvascular angina (PRIZE) trial. American Heart Journal, 229, pp. 70-80. (doi: 10.1016/j.ahj.2020.07.007)

Kunadian, V., Chieffo, A., Camici, P. G., Berry, C., Escaned, J., Maas, A. H. E. M., Prescott, E., Karam, N., Appelman, Y., Fraccaro, C., Louise Buchanan, G., Manzo-Silberman, S., Al-Lamee, R., Regar, E., Lansky, A., Abbott, J. D., Badimon, L., Duncker, D. J., Mehran, R., Capodanno, D., Baumbach, A. (2020) An EAPCI expert consensus document on ischaemia with non-obstructive coronary arteries in collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation endorsed by Coronary Vasomotor Disorders International Study Group. European Heart Journal, 41, pp. 3504-3520. (doi: 10.1093/eurheartj/ehaa503)

Dowsett, L., Higgins, E., Alanazi, S., Alshuwayer, N. A., Leiper, F. C., Leiper, J. (2020) ADMA: A key player in the relationship between vascular dysfunction and inflammation in atherosclerosis. Journal of Clinical Medicine, 9, (doi: 10.3390/jcm9093026)

Ford, T. J., Corcoran, D., Padmanabhan, S., Aman, A., Rocchiccioli, P., Good, R., McEntegart, M., Maguire, J. J., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., Yii, E., Sattar, N., Hsu, L.-Y., Arai, A. E., Oldroyd, K. G., Touyz, R. M., Davenport, A. P., Berry, C. (2020) Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction. European Heart Journal, 41, pp. 3239-3252. (doi: 10.1093/eurheartj/ehz915)

Sattar, N., Ho, F. K., Gill, J. M.R., Ghouri, N., Gray, S. R., Celis-Morales, C. A., Katikireddi, S. V., Berry, C., Pell, J. P., McMurray, J. J.V., Welsh, P. (2020) BMI and future risk for COVID-19 infection and death across sex, age and ethnicity: preliminary findings from UK biobank. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14, pp. 1149-1151. (doi: 10.1016/j.dsx.2020.06.060)

Ngandu Mpoyi, E., Cantini, M., Sin, Y. Y., Fleming, L., Zhou, D. W., Costell, M., Lu, Y., Kadler, K., García, A. J., Van Agtmael, T., Salmeron-Sanchez, M. (2020) Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts. Biomaterials, 252, (doi: 10.1016/j.biomaterials.2020.120090)

Ford, T. J., Ong, P., Sechtem, U., Beltrame, J., Camici, P. G., Crea, F., Kaski, J.-C., Bairey Merz, C. N., Pepine, C. J., Shimokawa, H., Berry, C. (2020) Assessment of vascular dysfunction in patients without obstructive coronary artery disease: why, how and when. JACC: Cardiovascular Interventions, 13, pp. 1847-1864. (doi: 10.1016/j.jcin.2020.05.052)

Rossitto, G., Mary, S., Chen, J. Y., Bodder, P., Chew, K. S., Neves, K. B., Alves, R. L., Montezano, A. C., Welsh, P., Petrie, M. C., Graham, D., Touyz, R. M., Delles, C. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, (doi: 10.1038/s41467-020-17820-2)

McClure, J. D., Ramsay, J. C., Berry, C. (2020) Pooled analysis of bleeding and major adverse cardiovascular events in clinical trials of time-constrained dual-antiplatelet therapy after percutaneous coronary intervention. Journal of the American Heart Association, 9, (doi: 10.1161/JAHA.120.017109)

Guzik, T. J., Mohiddin, S. A., Dimarco, A., Patel, V., Savvatis, K., Marelli-Berg, F. M., Madhur, M. S., Tomaszewksi, M., Maffia, P., D'Acquisto, F., Nicklin, S. A., Marian, A. J., Nosalski, R., Murray, E. C., Guzik, B., Berry, C., Touyz, R. M., Kreutz, R., Wang, D. W., Bhella, D., Sagliocco, O., Crea, F., Thomson, E. C., McInnes, I. B. (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research, 116, pp. 1666-1687. (doi: 10.1093/cvr/cvaa106)

Connelly, P. J., Jandeleit-Dahm, K. A.M., Delles, C. (2020) Sex and gender aspects in vascular pathophysiology. Clinical Science, 134, pp. 2203-2207. (doi: 10.1042/CS20200876)

Campbell, R. T., Jasilek, A., Mischak, H., Nkuipou-Kenfack, E., Latosinska, A., Welsh, P. I., Jackson, C. E., Cannon, J., McConnachie, A., Delles, C., McMurray, J. J.V. (2020) The novel urinary proteomic classifier HF1 has similar diagnostic and prognostic utility to BNP in heart failure. ESC Heart Failure, 7, pp. 1595-1604. (doi: 10.1002/ehf2.12708)

Demin, A., Løge, B., Zhiteneva, O., Nishida, C., Whiting, S., Rippin, H., Delles, C., Karymbaeva, S., Wickramasinghe, K., Breda, J. (2020) Trans fatty acid elimination policy in member states of the Eurasian Economic Union: implementation challenges and capacity for enforcement. Journal of Clinical Hypertension, 22, pp. 1328-1337. (doi: 10.1111/jch.13945)

Tarar, O. M., Ahmed, K. M., Nishtar, N. A., Achakzai, A. B. K., Gulzar, Y., Delles, C., Al-Jawaldeh, A. (2020) Understanding the complexities of prevalence of trans fat and its control in food supply in Pakistan. Journal of Clinical Hypertension, 22, pp. 1338-1346. (doi: 10.1111/jch.13943)

Dobbie, L. J., Mackin, S. T., Hogarth, K., Lonergan, F., Kannenkeril, D., Brooksbank, K., Delles, C. (2020) Validation of semi-automated flow mediated dilation measurement in healthy volunteers. Blood Pressure Monitoring, 25, pp. 216-223. (doi: 10.1097/MBP.0000000000000448)

Fong, L. C. W., Ford, T. J., da Costa, B. R., Jüni, P., Berry, C. (2020) Bias and loss to follow-up in cardiovascular randomized trials: a systematic review. Journal of the American Heart Association, 9, (doi: 10.1161/JAHA.119.015361)

Bulluck, H., Carberry, J., Carrick, D., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Mahrous, A., Ford, I., Oldroyd, K. G., Berry, C. (2020) Redefining adverse and reverse left ventricular remodeling by cardiovascular magnetic resonance following ST-segment elevation myocardial infarction and their implications on long-term prognosis. Circulation: Cardiovascular Imaging, 13, (doi: 10.1161/CIRCIMAGING.119.009937)

McFall, A. et al. (2020) UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: questionnaire and workshop proceedings. Journal of Cerebral Blood Flow and Metabolism, 40, pp. 1402-1414. (doi: 10.1177/0271678X20910552)

Dobbin, S. J.H., Mangion, K., Berry, C., Roditi, G., Basak, S., Sourbron, S., White, J., Venugopal, B., Touyz, R. M., Jones, R. J., Petrie, M. C., Lang, N. N. (2020) Cardiotoxicity and myocardial hypoperfusion associated with anti-VEGF therapies: prospective cardiac magnetic resonance imaging in patients with cancer. European Journal of Heart Failure, 22, pp. 1276-1277. (doi: 10.1002/ejhf.1847)

Currie, G., Mary, S., Delles, C. (2020) Is there a role for proteomics in diabetic renal disease? NDT Plus, 35, pp. 1133-1135. (doi: 10.1093/ndt/gfz017)

Riddell, A., McBride, M., Braun, T., Nicklin, S. A., Cameron, E., Loughrey, C. M., Martin, T. P. (2020) RUNX1: an emerging therapeutic target for cardiovascular disease. Cardiovascular Research, 116, pp. 1410-1423. (doi: 10.1093/cvr/cvaa034)

Al-Hussaini, A., Abdelaty, A. M.S.E.K., Gulsin, G. S., Arnold, J. R., Garcia-Guimaraes, M., Premawardhana, D., Budgeon, C., Wood, A., Natarajan, N., Mangion, K., Rakhit, R., Hoole, S. P., Johnson, T. W., Berry, C., Hudson, I., Gershlick, A. H., Ladwiniec, A., Kovac, J., Squire, I., Samani, N. J., Plein, S., McCann, G. P., Adlam, D. (2020) Chronic infarct size after spontaneous coronary artery dissection: implications for pathophysiology and clinical management. European Heart Journal, 41, pp. 2197-2205. (doi: 10.1093/eurheartj/ehz895)

Derakhshan, A. et al. (2020) Association of maternal thyroid function with birth weight: a systematic review and individual-participant data meta-analysis. Lancet Diabetes and Endocrinology, 8, pp. 501-510. (doi: 10.1016/S2213-8587(20)30061-9)

Sidik, N., McDermott, M., McEntegart, M. B., Berry, C. (2020) Chest pain without obstructive coronary artery disease: a case series report. European Heart Journal: Case Reports, 4, pp. 1-6. (doi: 10.1093/ehjcr/ytaa060)

Picone, D. S., Deshpande, R. A., Schultz, M. G., Fonseca, R., Campbell, N. R.C., Delles, C., Hecht-Olsen, M., Schutte, A. E., Stergiou, G., Padwal, R., Zhang, X.-H., Sharman, J. E. (2020) Nonvalidated home blood pressure devices dominate the online marketplace in Australia: major implications for cardiovascular risk management. Hypertension, 75, pp. 1593-1599. (doi: 10.1161/hypertensionaha.120.14719)

Delles, C., Olfert, M. (2020) Electronic cigarettes: how bad are they for your health? Cardiovascular Research, 116, pp. e64-e66. (doi: 10.1093/cvr/cvaa041)

Collison, D., McClure, J. D., Berry, C., Oldroyd, K. G. (2020) A randomized controlled trial of a physiology‐guided percutaneous coronary intervention optimization strategy: rationale and design of the TARGET FFR study. Clinical Cardiology, 43, pp. 414-422. (doi: 10.1002/clc.23342)

Maznyczka, A. M., Oldroyd, K. G., Greenwood, J. P., McCartney, P. J., Cotton, J., Lindsay, M., McEntegart, M., Rocchiccioli, J. P., Good, R., Robertson, K., Eteiba, H., Watkins, S., Shaukat, A., Petrie, C. J., Murphy, A., Petrie, M. C., Berry, C. (2020) Comparative significance of invasive measures of microvascular injury in acute myocardial infarction. Circulation: Cardiovascular Interventions, 13, (doi: 10.1161/CIRCINTERVENTIONS.119.008505)

Hennigan, B., Berry, C., Collison, D., Corcoran, D., Eteiba, H., Good, R., McEntegart, M., Watkins, S., McClure, J., Mangion, K., Ford, T., Petrie, M. C., Hood, S., Rocchiccioli, P., Shaukat, A., Lindsay, M., Oldroyd, K. G. (2020) Percutaneous coronary intervention versus medical therapy in patients with angina and grey-zone fractional flow reserve values: a randomised clinical trial. Heart, 106, pp. 714-715. (doi: 10.1136/heartjnl-2019-316075)

Li, W., Lazarus, A., Gao, H., Martinez De Azcona Naharro, A., Fontana, M., Hawkins, P., Biswas, S., Janiczek, R., Cox, J., Berry, C., Husmeier, D., Luo, X. (2020) Analysis of cardiac amyloidosis progression using model-based markers. Frontiers in Physiology, 11, (doi: 10.3389/fphys.2020.00324)

Nosalski, R., Siedlinski, M., Denby, L., Mcginnigle, E., Nowak, M., Nguyen Dinh Cat, A., Medina-Ruiz, L., Cantini, M., Skiba, D., Wilk, G., Osmenda, G., Rodor, J., Salmeron-Sanchez, M., Graham, G., Maffia, P., Graham, D., Baker, A. H., Guzik, T. J. (2020) T cell-derived miRNA-214 mediates perivascular fibrosis in hypertension. Circulation Research, 126, pp. 988-1003. (doi: 10.1161/CIRCRESAHA.119.315428)

Delles, C., Li, H., Touyz, R. M. (2020) ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19. Clinical Science, 134, pp. 747-750. (doi: 10.1042/CS20200363)

Tofte, N. et al. (2020) Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective observational study and embedded randomised placebo-controlled trial. Lancet Diabetes and Endocrinology, 8, pp. 301-312. (doi: 10.1016/S2213-8587(20)30026-7)

Frazier, S., McBride, M. W., Mulvana, H., Graham, D. (2020) From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia. Clinical Science, 134, pp. 1001-1025. (doi: 10.1042/CS20200023)

Jackson, A. M., Zhang, R., Findlay, I., Robertson, K., Lindsay, M., Morris, T., Forbes, B., Papworth, R., McConnachie, A., Mangion, K., Jhund, P. S., McCowan, C., Berry, C. (2020) Healthcare disparities for women hospitalised with myocardial infarction and angina. European Heart Journal: Quality of Care and Clinical Outcomes, 6, pp. 156-165. (doi: 10.1093/ehjqcco/qcz040)

Mangion, K., Adamson, P. D., Williams, M. C., Hunter, A., Pawade, T., Shah, A. S.V., Lewis, S., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D., McAllister, D., Berry, C. (2020) Sex associations and computed tomography coronary angiography-guided management in patients with stable chest pain. European Heart Journal, 41, pp. 1337-1345. (doi: 10.1093/eurheartj/ehz903)

Berry, C., Duncker, D. J. (2020) Coronary microvascular disease: the next frontier for Cardiovascular Research. Cardiovascular Research, 116, pp. 737-740. (doi: 10.1093/cvr/cvaa035)

Ford, T. J., Berry, C. (2020) Angina: contemporary diagnosis and management. Heart, 106, pp. 387-398. (doi: 10.1136/heartjnl-2018-314661)

Sidik, N. P., McEntegart, M., Roditi, G., Ford, T. J., McDermott, M., Morrow, A., Byrne, J., Adams, J., Hargreaves, A., Oldroyd, K. G., Stobo, D., Wu, O., Messow, C.-M., McConnachie, A., Berry, C. (2020) Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Function and CT Coronary Angiogram (CorCTCA) study. American Heart Journal, 221, pp. 48-59. (doi: 10.1016/j.ahj.2019.11.015)

Maznyczka, A. M., McCartney, P. J., Oldroyd, K. G., Lindsay, M., McEntegart, M., Eteiba, H., Rocchiccioli, P., Good, R., Shaukat, A., Robertson, K., Kodoth, V., Greenwood, J. P., Cotton, J. M., Hood, S., Watkins, S., Macfarlane, P. W., Kennedy, J., Tait, C., Welsh, P., Sattar, N., Collison, D., Gillespie, L., McConnachie, A., Berry, C. (2020) Effects of intracoronary alteplase on microvascular function in acute myocardial infarction. Journal of the American Heart Association, 9, (doi: 10.1161/JAHA.119.014066)

Morrow, A., Sidik, N., Berry, C. (2020) ISCHEMIA: new questions from a landmark trial. Cardiovascular Research, 116, pp. e23-e25. (doi: 10.1093/cvr/cvz343)

McQueen, A., Kennedy, S., McCormick, C., Aggarwal, A., McGinty, S. (2020) Mathematical Modelling of the Effect of Drug on Smooth Muscle Cell Proliferation.

Crouch, S. H., Botha-Le Roux, S., Delles, C., Graham, L. A., Schutte, A. E. (2020) Distinct inflammatory mediator patterns in young black and white adults: The African-PREDICT study. Cytokine, 126, (doi: 10.1016/j.cyto.2019.154894)

Maznyczka, A. M. et al. (2020) One-year outcomes after low-dose intracoronary alteplase during primary percutaneous coronary intervention. The T-TIME randomized trial. Circulation: Cardiovascular Interventions, 13, (doi: 10.1161/CIRCINTERVENTIONS.119.008855)

Ford, T. J., Khan, A., Docherty, K. F., Jackson, A., Morrow, A., Sidik, N., Rocchiccioli, P., Good, R., Eteiba, H., Watkins, S., Shaukat, A., Lindsay, M., Robertson, K., Petrie, M., Berry, C., Oldroyd, K., McEntegart, M. (2020) Sex differences in procedural and clinical outcomes following rotational atherectomy. Catheterization and Cardiovascular Interventions, 95, pp. 232-241. (doi: 10.1002/ccd.28373)

Schlosser, K., Kaur, A., Dayan, N., Stewart, D. J., Pilote, L., Delles, C. (2020) Circulating miR-206 and Wnt-signaling are associated with cardiovascular complications and a history of preeclampsia in women. Clinical Science, 134, pp. 87-101. (doi: 10.1042/CS20190920)

Ford, T. J., Stanley, B., Sidik, N., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., Yii, E., McCartney, P., Corcoran, D., Collison, D., Rush, C., Sattar, N., McConnachie, A., Touyz, R. M., Oldroyd, K. G., Berry, C. (2020) 1-year outcomes of angina management guided by invasive coronary function testing (CorMicA) JACC: Cardiovascular Interventions, 13, pp. 33-45. (doi: 10.1016/j.jcin.2019.11.001)

Chapman, A. R., Adamson, P. D., Shah, A. S.V., Anand, A., Strachan, F. E., Ferry, A. V., Lee, K. K., Berry, C., Findlay, I., Cruikshank, A., Reid, A., Gray, A., Collinson, P. O., Apple, F., McAllister, D., McAllister, D. A., Maguire, D., Fox, K. A.A., Vallejos, C. A., Keerie, C., Weir, C. J., Newby, D. E., Mills, N. L. (2020) High-sensitivity cardiac troponin and the universal definition of myocardial infarction. Circulation, 141, pp. 161-171. (doi: 10.1161/CIRCULATIONAHA.119.042960)

Sidik, N., Morrow, A., Berry, C. (2020) Human microcirculation in ischemic heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 40, pp. 11-13. (doi: 10.1161/ATVBAHA.119.313579)

McArthur, L., Riddell, A., Chilton, L., Smith, G. L., Nicklin, S. A. (2020) Regulation of connexin 43 by interleukin 1β in adult rat cardiac fibroblasts and effects in an adult rat cardiac myocyte: fibroblast co-culture model. Heliyon, 6, (doi: 10.1016/j.heliyon.2019.e03031)

Mary, S., Currie, G., Schutte, A. E., Delles, C. (2020) Cardiovascular proteomics. Academic Press

Heggie, R., Wu, O., Boyd, K., Lee, M. M.Y., Petrie, M. C., McEntegart, M., Berry, C. (2020) Does routine invasive management benefit patients presenting with an acute coronary syndrome and a history of bypass surgery? The use of clinical outcomes compared with cost-effectiveness outcomes.

McCartney, P. J., Maznyczka, A. M., Eteiba, H., McEntegart, M., Oldroyd, K. G., Greenwood, J. P., Mareida, N., Schmitt, M., McCann, G. P., Fairbairn, T., McAlindon, E., Tait, C., Welsh, P., Sattar, N., Orchard, V., Corcoran, D., Ford, T. J., Radjenovic, A., Ford, I., McConnachie, A., Berry, C. (2020) Low-dose alteplase during primary percutaneous coronary intervention according to ischemic time. Journal of the American College of Cardiology, 75, pp. 1406-1421. (doi: 10.1016/j.jacc.2020.01.041)

2019

Tardif, J.-C. et al. (2019) Efficacy and safety of low-dose colchicine after myocardial infarction. New England Journal of Medicine, 381, pp. 2497-2505. (doi: 10.1056/NEJMoa1912388)

Neves, K. B., Harvey, A. P., Moreton, F., Montezano, A. C., Rios, F. J., Alves-Lopes, R., Nguyen Dinh Cat, A., Rocchiccioli, P., Delles, C., Joutel, A., Muir, K., Touyz, R. M. (2019) ER stress and Rho kinase activation underlie the vasculopathy of CADASIL. JCI Insight, 4, (doi: 10.1172/jci.insight.131344)

Nagel, E., Berry, C. (2019) Magnetic resonance perfusion or fractional flow reserve in coronary disease. Reply. New England Journal of Medicine, 381, pp. 2277-2278. (doi: 10.1056/NEJMc1913968)

Connelly, P. J., Freel, E. M., Perry, C., Ewan, J., Touyz, R. M., Currie, G., Delles, C. (2019) Gender-affirming hormone therapy, vascular health and cardiovascular disease in transgender adults. Hypertension, 74, pp. 1266-1274. (doi: 10.1161/HYPERTENSIONAHA.119.13080)

Ford, T. J., Yii, E., Sidik, N., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., McCartney, P., Corcoran, D., Collison, D., Rush, C., Stanley, B., McConnachie, A., Sattar, N., Touyz, R. M., Oldroyd, K. G., Berry, C. (2019) Ischemia and no obstructive coronary artery disease: prevalence and correlates of coronary vasomotion disorders. Circulation: Cardiovascular Interventions, 12, (doi: 10.1161/CIRCINTERVENTIONS.119.008126)

Avtaar Singh, S. S., Das De, S., Rushton, S., Berry, C., Al-Attar, N. (2019) PREDICTA: a model to predict primary graft dysfunction after adult heart transplantation in the United Kingdom. Journal of Cardiac Failure, 25, pp. 971-977. (doi: 10.1016/j.cardfail.2019.07.009)

Adamson, C., Rocchiccioli, P., Brogan, R., Berry, C., Ford, T. J. (2019) Post-operative myocardial infarction following aortic root surgery with coronary reimplantation: a case series treated with percutaneous coronary intervention. European Heart Journal: Case Reports, 3, pp. 1-6. (doi: 10.1093/ehjcr/ytz181)

Cameron, A. C., Lang, N. N., Dominiczak, A. F., Jennings, G. L.R., Batlle, D., Bursztyn, M., Chugh, A. R., Floras, J. S., Taler, S. J., Touyz, R. M., Delles, C. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74, pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343)

Bularga, A., Lee, K. K., Stewart, S., Ferry, A. V., Chapman, A. R., Marshall, L., Strachan, F. E., Cruickshank, A., Maguire, D., Berry, C., Findlay, I., Shah, A. S.V., Newby, D. E., Mills, N. L., Anand, A. (2019) High-sensitivity troponin and the application of risk stratification thresholds in patients with suspected acute coronary syndrome. Circulation, 140, pp. 1557-1568. (doi: 10.1161/CIRCULATIONAHA.119.042866)

Davies, V., Noè, U., Lazarus, A., Gao, H., Macdonald, B., Berry, C., Luo, X., Husmeier, D. (2019) Fast parameter inference in a biomechanical model of the left ventricle by using statistical emulation. Journal of the Royal Statistical Society: Series C (Applied Statistics), 68, pp. 1555-1576. (doi: 10.1111/rssc.12374)

van Kralingen, J., McFall, A., Ord, E. N.J., Coyle, T. F., Bissett, M., McClure, J. D., McCabe, C., Macrae, I. M., Dawson, J., Work, L. M. (2019) Altered extracellular vesicle microrna expression in ischemic stroke and small vessel disease. Translational Stroke Research, 10, pp. 495-508. (doi: 10.1007/s12975-018-0682-3)

Rahman, H., Corcoran, D., Aetesam-Ur-Rahman, M., Hoole, S. P., Berry, C., Perera, D. (2019) Diagnosis of patients with angina and non-obstructive coronary disease in the catheter laboratory. Heart, 105, pp. 1536-1542. (doi: 10.1136/heartjnl-2019-315042)

Hausenloy, D. J. et al. (2019) Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial. Lancet, 394, pp. 1415-1424. (doi: 10.1016/S0140-6736(19)32039-2)

Adamson, P. D., Williams, M. C., Dweck, M. R., Mills, N. L., Boon, N. A., Daghem, M., Bing, R., Moss, A. J., Mangion, K., Flather, M., Forbes, J., Hunter, A., Norrie, J., Shah, A. S.V., Timmis, A. D., van Beek, E. J.R., Ahmadi, A. A., Leipsic, J., Narula, J., Newby, D. E., Roditi, G., McAllister, D. A., Berry, C. (2019) Guiding therapy by coronary CT angiography improves outcomes in patients with stable chest pain. Journal of the American College of Cardiology, 74, pp. 2058-2070. (doi: 10.1016/j.jacc.2019.07.085)

Deuchar, G. A., Van Kralingen, J. C., Work, L. M., Santosh, C., Muir, K. W., McCabe, C., Macrae, I. M. (2019) Preclinical validation of the therapeutic potential of Glasgow Oxygen Level Dependent (GOLD) technology: A theranostic for acute stroke. Translational Stroke Research, 10, pp. 583-595. (doi: 10.1007/s12975-018-0679-y)

Lee, K. K., Ferry, A. V., Anand, A., Strachan, F. E., Chapman, A. R., Kimenai, D. M., Meex, S. J.R., Berry, C., Findlay, I., Reid, A., Cruickshank, A., Gray, A., Collinson, P. O., Apple, F. S., McAllister, D. A., Maguire, D., Fox, K. A.A., Newby, D. E., Tuck, C., Keerie, C., Weir, C. J., Shah, A. S.V., Mills, N. L. (2019) Sex-specific thresholds of high-sensitivity troponin in patients with suspected acute coronary syndrome. Journal of the American College of Cardiology, 74, pp. 2032-2043. (doi: 10.1016/j.jacc.2019.07.082)

Gatseva, A., Sin, Y. Y., Brezzo, G., Van Agtmael, T. (2019) Basement membrane collagens and disease mechanisms. Essays in Biochemistry, 63, pp. 297-312. (doi: 10.1042/EBC20180071)

Iliodromiti, S., Sattar, N., Delles, C., Nelson, S. M., Gill, J. M.R., Lumsden, M. (2019) Menopausal hot flashing and endothelial function in two vascular beds: findings from a cross-sectional study of postmenopausal women. Menopause, 26, pp. 1002-1009. (doi: 10.1097/GME.0000000000001386)

Dérimay, F., Johnson, N. P., Zimmermann, F. M., Adjedj, J., Witt, N., Hennigan, B., Koo, B.‐K., Barbato, E., Esposito, G., Trimarco, B., Rioufol, G., Park, S.‐J., Baptista, S. B., Chrysant, G. S., Leone, A. M., Jeremias, A., Berry, C., De Bruyne, B., Oldroyd, K. G., Pijls, N. H.J., Fearon, W. F. (2019) Predictive factors of discordance between the instantaneous wave‐free ratio and fractional flow reserve. Catheterization and Cardiovascular Interventions, 94, pp. 356-363. (doi: 10.1002/ccd.28116)

Avtaar Singh, S. S., Dalzell, J. R., Berry, C., Al-Attar, N. (2019) Primary graft dysfunction after heart transplantation: a thorn amongst the roses. Heart Failure Reviews, 24, pp. 805-820. (doi: 10.1007/s10741-019-09794-1)

Alganga, H. S. F., Almabrouk, T. A.M., Katwan, O. J., Daly, C. J., Pyne, S., Pyne, N. J., Kennedy, S. (2019) Short periods of hypoxia upregulate sphingosine kinase 1 and increase vasodilation of arteries to Sphingosine 1-phosphate via S1P3. Journal of Pharmacology and Experimental Therapeutics, 371, pp. 63-74. (doi: 10.1124/jpet.119.257931)

Garcia Cordoba, C., Daly, C. J. (2019) The organisation of vascular smooth muscle cells; a quantitative Fast Fourier Transform (FFT) based assessment. Translational Research in Anatomy, 16, (doi: 10.1016/j.tria.2019.100047)

Yang, Y., Gao, H., Berry, C., Radjenovic, A., Husmeier, D. (2019) Quantification of Myocardial Perfusion Lesions Using Spatially Variant Finite Mixture Modelling of DCE-MRI. (doi: 10.11159/icsta19.26)

Husmeier, D., Lazarus, A., Noè, U., Davies, V., Borowska, A., Macdonald, B., Gao, H., Berry, C., Luo, X. (2019) Statistical Emulation of Cardiac Mechanics: an Important Step Towards a Clinical Decision Support System. (doi: 10.11159/icsta19.29)

Korevaar, T. I. M. et al. (2019) Association of thyroid function test abnormalities and thyroid autoimmunity with preterm birth: a systematic review and meta-analysis. JAMA: Journal of the American Medical Association, 322, pp. 632-641. (doi: 10.1001/jama.2019.10931)

Johnson, N. P., Li, W., Chen, X., Hennigan, B., Watkins, S., Berry, C., Fearon, W. F., Oldroyd, K. G. (2019) Diastolic pressure ratio: new approach and validation vs. the instantaneous wave-free ratio. European Heart Journal, 40, pp. 2585-2594. (doi: 10.1093/eurheartj/ehz230)

Lee, M. M.Y. et al. (2019) Invasive versus medical management in patients with prior coronary artery bypass surgery with a non-ST segment elevation acute coronary syndrome: a pilot randomized controlled trial. Circulation: Cardiovascular Interventions, 12, (doi: 10.1161/CIRCINTERVENTIONS.119.007830)

Crea, F., Bairey Merz, C. N., Beltrame, J. F., Berry, C., Camici, P. G., Kaski, J. C., Ong, P., Pepine, C. J., Sechtem, U., Shimokawa, H. (2019) Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization. European Heart Journal, 40, pp. 2455-2462. (doi: 10.1093/eurheartj/ehy857)

Noè, U., Lazarus, A., Gao, H., Davies, V., Macdonald, B., Mangion, K., Berry, C., Luo, X., Husmeier, D. (2019) Gaussian process emulation to accelerate parameter estimation in a mechanical model of the left ventricle: a critical step towards clinical end-user relevance. Journal of the Royal Society: Interface, 16, (doi: 10.1098/rsif.2019.0114)

Ibanez, B., Aletras, A. H., Arai, A. E., Arheden, H., Bax, J., Berry, C., Bucciarelli-Ducci, C., Croisille, P., Dall'Armellina, E., Dharmakumar, R., Eitel, I., Fernández-Jiménez, R., Friedrich, M. G., García-Dorado, D., Hausenloy, D. J., Kim, R. J., Kozerke, S., Kramer, C. M., Salerno, M., Sánchez-González, J., Sanz, J., Fuster, V. (2019) Cardiac MRI endpoints in myocardial infarction experimental and clinical trials: JACC scientific expert panel. Journal of the American College of Cardiology, 74, pp. 238-256. (doi: 10.1016/j.jacc.2019.05.024)

Ubaid, S., Ford, T. J., Berry, C., Murray, H. M., Wrigley, B., Khan, N., Thomas, M. R., Armesilla, A. L., Townend, J. N., Khogali, S. S., Munir, S., Martins, J., Hothi, S. S., McAlindon, E. J., Cotton, J. M. (2019) Cangrelor versus ticagrelor in patients treated with primary percutaneous coronary intervention: impact on platelet activity, myocardial microvascular function and infarct size: a randomized controlled trial. Thrombosis and Haemostasis, 119, pp. 1171-1181. (doi: 10.1055/s-0039-1688789)

Doszpoly, A., de la Cuesta, F., Lopez-Gordo, E., Bénézech, C., Nicklin, S. A., Baker, A. H. (2019) Human adenovirus serotype 5 is sensitive to IgM-independent neutralization in vitro and in vivo. Viruses, 11, (doi: 10.3390/v11070616)

Niccoli, G., Montone, R. A., Ibanez, B., Thiele, H., Crea, F., Heusch, G., Bulluck, H., Hausenloy, D. J., Berry, C., Stiermaier, T., Camici, P. G., Eitel, I. (2019) Optimized treatment of ST-elevation myocardial infarction: the unmet need to target coronary microvascular obstruction as primary treatment goal to further improve prognosis. Circulation Research, 125, pp. 245-258. (doi: 10.1161/circresaha.119.315344)

Katwan, O. J., Alghamdi, F., Almabrouk, T. A., Mancini, S. J., Kennedy, S., Oakhill, J. S., Scott, J. W., Salt, I. P. (2019) AMP-activated protein kinase complexes containing the β2 regulatory subunit are upregulated during and contribute to adipogenesis. Biochemical Journal, 476, pp. 1725-1740. (doi: 10.1042/BCJ20180714)

Nagel, E., Greenwood, J. P., McCann, G. P., Bettencourt, N., Shah, A. M., Hussain, S. T., Perera, D., Plein, S., Bucciarelli-Ducci, C., Paul, M., Westwood, M. A., Marber, M., Richter, W.-S., Puntmann, V. O., Schwenke, C., Schulz-Menger, J., Das, R., Wong, J., Hausenloy, D. J., Steen, H., Berry, C. (2019) Magnetic resonance perfusion or fractional flow reserve in coronary disease. New England Journal of Medicine, 380, pp. 2418-2428. (doi: 10.1056/NEJMoa1716734)

McKittrick, C., McKee, S., Kennedy, S., Oldroyd, K., Wheel, M., Pontrelli, G., Dixon, S., Mcginty, S., McCormick, C. (2019) Combining mathematical modelling with in vitro experiments to predict in vivo drug-eluting stent performance. Journal of Controlled Release, 303, pp. 151-161. (doi: 10.1016/j.jconrel.2019.03.012)

Mikolajczyk, T. P., Nosalski, R., Skiba, D. S., Koziol, J., Mazur, M., Justo Junior, A. S., Kowalczyk, P., Kusmierczyk, Z., Schramm Luc, A., Luc, K., Maffia, P., Graham, D., Kiss, A. K., Naruszewicz, M., Guzik, T. J. (2019) 1,2,3,4,6 penta-O -galloyl-β-D-glucose modulates perivascular inflammation and prevents vascular dysfunction in angiotensin II-induced hypertension. British Journal of Pharmacology, 176, pp. 1951-1965. (doi: 10.1111/bph.14583)

Haig, C., Carrick, D., Carberry, J., Mangion, K., Maznyczka, A., Wetherall, K., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ahmed, N., May, V. T. Y., Ford, I., Radjenovic, A., Welsh, P., Sattar, N., Oldroyd, K. G., Berry, C. (2019) Current smoking and prognosis after acute ST-segment elevation myocardial infarction: new pathophysiological insights. JACC: Cardiovascular Imaging, 12, pp. 993-1003. (doi: 10.1016/j.jcmg.2018.05.022)

Daly, C. J. (2019) From confocal microscope to virtual reality and computer games; technical and educational considerations. Infocus Magazine, 54, pp. 51-59.

Kinch, K., Fullerton, J. L., Stewart, W. (2019) One-hundred years (and counting) of blast-associated traumatic brain injury. Journal of the Royal Army Medical Corps, 165, pp. 180-182. (doi: 10.1136/jramc-2017-000867)

Czesnikiewicz-Guzik, M., Nosalski, R., Mikolajczyk, T. P., Vidler, F., Dohnal, T., Dembowska, E., Graham, D., Harrison, D. G., Guzik, T. J. (2019) Th1 type immune responses to Porphyromonas gingivalis antigens exacerbate angiotensin II dependent hypertension and vascular dysfunction. British Journal of Pharmacology, 176, pp. 1922-1931. (doi: 10.1111/bph.14536)

Welsh, C., Welsh, P., Jhund, P., Delles, C., Celis-Morales, C., Lewsey, J., Gray, S., Lyall, D., Iliodromiti, S., Gill, J., Sattar, N., Mark, P. (2019) Urinary sodium excretion, blood pressure and risk of future cardiovascular disease and mortality in subjects without prior cardiovascular disease. Hypertension, 73, pp. 1202-1209. (doi: 10.1161/HYPERTENSIONAHA.119.12726)

Maznyczka, A. M., Oldroyd, K. G., McCartney, P., McEntegart, M., Berry, C. (2019) The potential use of the index of microcirculatory resistance to guide stratification of patients for adjunctive therapy in acute myocardial infarction. JACC: Cardiovascular Interventions, 12, pp. 951-966. (doi: 10.1016/j.jcin.2019.01.246)

Ford, T., Berry, C. (2019) How to diagnose and manage angina without obstructive coronary artery disease: Lessons from the British Heart Foundation CorMicA trial. Interventional Cardiology Review, 14, pp. 76-82. (doi: 10.15420/icr.2019.04.R1)

Schanstra, J. P., Luong, T. T.D., Makridakis, M., Van Linthout, S., Lygirou, V., Latosinska, A., Alesutan, I., Boehme, B., Schelski, N., Von Lewinski, D., Mullen, W., Nicklin, S., Delles, C., Feuillet, G., Denis, C., Lang, F., Pieske, B., Bascands, J.-L., Mischak, H., Saulnier-Blache, J.-S., Voelkl, J., Vlahou, A., Klein, J. (2019) Systems biology identifies cytosolic PLA2 as a target in vascular calcification treatment. JCI Insight, 4, (doi: 10.1172/jci.insight.125638)

Small, H. Y., McNeilly, S., Mary, S., Sheikh, A. M., Delles, C. (2019) Resistin mediates sex-dependent effects of perivascular adipose tissue on vascular function in the SHRSP. Scientific Reports, 9, (doi: 10.1038/s41598-019-43326-z)

Singh, A., Horsfield, M. A., Bekele, S., Greenwood, J. P., Dawson, D. K., Berry, C., Hogrefe, K., Kelly, D. J., Houston, J. G., Guntur Ramkumar, P., Uddin, A., Suzuki, T., McCann, G. P. (2019) Aortic stiffness in aortic stenosis assessed by cardiovascular MRI: a comparison between bicuspid and tricuspid valves. European Radiology, 29, pp. 2340-2349. (doi: 10.1007/s00330-018-5775-6)

Ferreira, J. P. et al. (2019) Proteomic bioprofiles and mechanistic pathways of progression to heart failure: the HOMAGE study. Circulation, 12, (doi: 10.1161/CIRCHEARTFAILURE.118.005897)

Olson, E., Pravenec, M., Landa, V., Koh-Tan, H. H. C., Dominiczak, A. F., McBride, M. W., Graham, D. (2019) Transgenic overexpression of glutathione S-transferase μ-type 1 reduces hypertension and oxidative stress in the stroke-prone spontaneously hypertensive rat. Journal of Hypertension, 37, pp. 985-996. (doi: 10.1097/HJH.0000000000001960)

Currie, G., Delles, C. (2019) Vascular biomedicine in an era of chronic disease and multimorbidity. Clinical Science, 133, pp. 1137-1143. (doi: 10.1042/CS20180764)

Ugusman, A. B., Riddell, A., Kennedy, S. (2019) Effect of peroxynitrite (ONOO−) on the function of murine perivascular adipose tissue. Pharmacology and Pharmacy, 10, pp. 194-204. (doi: 10.4236/pp.2019.104017)

Maznyczka, A. M., Carrick, D., Carberry, J., Mangion, K., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Ford, I., Welsh, P., Sattar, N., Oldroyd, K. G., Berry, C. (2019) Sex-based associations with microvascular injury and outcomes after ST-segment elevation myocardial infarction. Open Heart, 6, (doi: 10.1136/openhrt-2018-000979)

Mangion, K., Burke, N. M.M., Mccomb, C., Carrick, D., Woodward, R., Berry, C. (2019) Feature-tracking myocardial strain in healthy adults- a magnetic resonance study at 3.0 tesla. Scientific Reports, 9, (doi: 10.1038/s41598-019-39807-w)

Mangion, K., Carrick, D., Clerfond, G., Rush, C., McComb, C., Oldroyd, K. G., Petrie, M. C., Eteiba, H., Lindsay, M., McEntegart, M., Hood, S., Watkins, S., Davie, A., Auger, D. A., Zhong, X., Epstein, F. H., Haig, C. E., Berry, C. (2019) Predictors of segmental myocardial functional recovery in patients after an acute ST-elevation myocardial infarction. European Journal of Radiology, 112, pp. 121-129. (doi: 10.1016/j.ejrad.2019.01.010)

Lucas-Herald, A. K., Zürbig, P., Mason, A., Kinning, E., Brown, C. E., Mansoorian, B., Mullen, W., Ahmed, S. F., Delles, C. (2019) Proteomic evidence of biological aging in a child with a compound heterozygous ZMPSTE24 mutation. Proteomics Clinical Applications, 13, (doi: 10.1002/prca.201800135)

Arroja, M.M.C., Reid, E., Roy, L.A., Vallatos, A.V., Holmes, W.M., Nicklin, S.A., Work, L.M., McCabe, C. (2019) Assessing the effects of Ang-(1-7) therapy following transient middle cerebral artery occlusion. Scientific Reports, 9, (doi: 10.1038/s41598-019-39102-8)

Jones, F. E., Murray, L. S., McNeilly, S., Dean, A., Aman, A., Lu, Y., Nikolova, N., Malomgre, R., Horsburgh, K., Holmes, W. M., Kadler, K. E., Van Agtmael, T. (2019) 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease. Human Molecular Genetics, 28, pp. 628-638. (doi: 10.1093/hmg/ddy369)

Avtaar Singh, S. S., Das De, S., Nappi, F., Al-Adhami, A., Hegazy, Y., Dalzell, J., Doshi, H., Sinclair, A., Curry, P., Petrie, M., Berry, C., Al-Attar, N. (2019) Mechanical circulatory support for refractory cardiogenic shock post-acute myocardial infarction-a decade of lessons. Journal of Thoracic Disease, 11, pp. 542-548. (doi: 10.21037/jtd.2019.01.21)

Mangion, K., Carrick, D., Carberry, J., Mahrous, A., McComb, C., Oldroyd, K. G., Eteiba, H., Lindsay, M., McEntegart, M., Hood, S., Petrie, M. C., Watkins, S., Davie, A., Zhong, X., Epstein, F. H., Haig, C. E., Berry, C. (2019) Circumferential strain predicts major adverse cardiovascular events following an acute ST-segment-elevation myocardial infarction. Radiology, 290, pp. 329-337. (doi: 10.1148/radiol.2018181253)

Avtaar Singh, S. S., Banner, N. R., Rushton, S., Simon, A. R., Berry, C., Al-Attar, N. (2019) ISHLT primary graft dysfunction incidence, risk factors and outcome: a UK national study. Transplantation, 103, pp. 336-343. (doi: 10.1097/TP.0000000000002220)

Ford, T., Corcoran, D., Sidik, N., Oldroyd, K. G., Rocchiccioli, P., McEntegart, M., Berry, C. (2019) MINOCA: Requirement for definitive diagnostic work-up. Heart, Lung and Circulation, 28, pp. e4-e6. (doi: 10.1016/j.hlc.2018.04.001)

McCartney, P. J., Berry, C. (2019) Redefining successful primary PCI. European Heart Journal, 20, pp. 133-135. (doi: 10.1093/ehjci/jey159)

Berry, C., Sidik, N., Pereira, A. C., Ford, T. J., Touyz, R. M., Kaski, J.-C., Hainsworth, A. H. (2019) Small-vessel disease in the heart and brain: current knowledge, unmet therapeutic need, and future directions. Journal of the American Heart Association, 8, (doi: 10.1161/JAHA.118.011104)

Hall, J.L., Owen, L., Riddell, A., Church, D.B., Brodbelt, D.C., O'Neill, D.G. (2019) Urinary incontinence in male dogs under primary veterinary care in England: prevalence and risk factors. Journal of Small Animal Practice, 60, pp. 86-95. (doi: 10.1111/jsap.12951)

Greig, F. H., Nather, K., Ballantyne, M. D., Kazi, Z. H., Alganga, H., Ewart, M.-A., Zaborska, K. E., Fertig, B., Pyne, N. J., Pyne, S., Kennedy, S. (2019) Requirement for sphingosine kinase 1 in mediating phase 1 of the hypotensive response to anandamide in the anaesthetised mouse. European Journal of Pharmacology, 842, pp. 1-9. (doi: 10.1016/j.ejphar.2018.10.027)

McCartney, P. J. et al. (2019) Effect of low-dose intracoronary alteplase during primary percutaneous coronary intervention on microvascular obstruction in patients with acute myocardial infarction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321, pp. 56-68. (doi: 10.1001/jama.2018.19802)

Kerr, D. M.I., Brooksbank, K. J.M., Taylor, R. G., Pinel, K., Rios, F. J., Touyz, R. M., Delles, C. (2019) Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study. Journal of Hypertension, 37, pp. 154-166. (doi: 10.1097/HJH.0000000000001890)

Berry, C., Corcoran, D., Mangion, K. (2019) Cardiovascular health technology assessment: recommendations to improve the quality of evidence. Open Heart, 6, (doi: 10.1136/openhrt-2018-000930)

Mazlan-Kepli, W., Dawson, J., Berry, C., Walters, M. (2019) Cessation of dual antiplatelet therapy and cardiovascular events following acute coronary syndrome. Heart, 105, pp. 67-74. (doi: 10.1136/heartjnl-2018-313148)

Morrow, A., Nordin, S., O'Boyle, P., Berry, C. (2019) 'Acute micro-coronary syndrome': detailed coronary physiology in a patient with Takotsubo cardiomyopathy. BMJ Case Reports, 12, (doi: 10.1136/bcr-2019-229618)

Kennedy, S., Touyz, R. M. (2019) Anatomy and pharmacology of vessels. Springer

Daly, C. J. (2019) Autonomic innervation of visceral and peri-vascular adipose tissue. Editora UFPE

Ravassa, S., Delles, C., Currie, G., Díez, J. (2019) Biomarkers of cardiovascular disease. Springer

Purnama Sidik, N., McCartney, P., Berry, C. (2019) Coronary microvascular disease. Springer

Small, H. Y., Currie, G., Delles, C. (2019) Endothelial dysfunction. Springer

Daly, C. J. (2019) Examining vascular structure and function using confocal microscopy and 3D imaging techniques. Springer

Daly, C. J. (2019) Imaging the vascular wall: from microscope to virtual reality. Springer

Corcoran, D., Ford, T. J., Berry, C. (2019) Stable coronary syndromes. Springer

McFall, A., Dawson, J., Work, L. M. (2019) Stroke. Springer

(2019) Textbook of Vascular Medicine. (doi: 10.1007/978-3-030-16481-2)

Graham, D. (2019) Vascular physiology. Springer

Nather, K., Loughrey, C. M., Nicklin, S. A. (2019) Vasoactive peptides: renin-angiotensin-aldosterone system. Springer

2018

Ford, T. J., Stanley, B., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., Yii, E., Sidik, N., McCartney, P., Corcoran, D., Collison, D., Rush, C., McConnachie, A., Touyz, R., Oldroyd, K., Berry, C. (2018) Stratified medical therapy using invasive coronary function testing in angina: CorMicA trial. Journal of the American College of Cardiology, 72, pp. 2841-2855. (doi: 10.1016/j.jacc.2018.09.006)

Ford, T. J., Rocchiccioli, P., Good, R., McEntegart, M., Eteiba, H., Watkins, S., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., Yii, E., Sidik, N., Harvey, A., Montezano, A. C., Beattie, E., Haddow, L., Oldroyd, K. G., Touyz, R. M., Berry, C. (2018) Systemic microvascular dysfunction in microvascular and vasospastic angina. European Heart Journal, 39, pp. 4086-4097. (doi: 10.1093/eurheartj/ehy529)

Rossitto, G., Touyz, R. M., Petrie, M. C., Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132, pp. 2609-2613. (doi: 10.1042/CS20180575)

Sliz, E. et al. (2018) Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment. Circulation, 138, pp. 2499-2512. (doi: 10.1161/CIRCULATIONAHA.118.034942)

Graham, L. A., Aman, A., Campbell, D. D., Augley, J., Graham, D., McBride, M. W., Fraser, N. J., Ferreri, N. R., Dominiczak, A. F., Padmanabhan, S. (2018) Salt stress in the renal tubules is linked to TAL specific expression of uromodulin and an upregulation of heat shock genes. Physiological Genomics, 50, pp. 964-972. (doi: 10.1152/physiolgenomics.00057.2018)

Hietamies, T. M., Ostrowski, C., Pei, Z., Feng, L., McCabe, C., Work, L. M., Quinn, T. J. (2018) Variability of functional outcome measures used in animal models of stroke and vascular cognitive impairment – a review of contemporary studies. Journal of Cerebral Blood Flow and Metabolism, 38, pp. 1872-1884. (doi: 10.1177/0271678X18799858)

Guzik, T. J., Antoniades, C., Baker, A. H., Harrison, D. G., Loughrey, C. M., Maffia, P., Murphy, E., Nicklin, S. A., Peter, K., Pearson, J., Casadei, B. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114, pp. 1565-1568. (doi: 10.1093/cvr/cvy214)

Tofte, N. et al. (2018) Characteristics of high- and low-risk individuals in the PRIORITY study: urinary proteomics and mineralocorticoid receptor antagonism for prevention of diabetic nephropathy in Type 2 diabetes. Diabetic Medicine, 35, pp. 1375-1382. (doi: 10.1111/dme.13669)

Dayan, N., Schlosser, K., Stewart, D. J., Delles, C., Kaur, A., Pilote, L. (2018) Circulating microRNAs implicate multiple atherogenic abnormalities in the long-term cardiovascular sequelae of preeclampsia. American Journal of Hypertension, 31, pp. 1093-1097. (doi: 10.1093/ajh/hpy069)

Berry, C., Mangion, K., Pathan, F. (2018) Spotlight on strain following myocardial infarction. JACC: Cardiovascular Imaging, 11, pp. 1445-1447. (doi: 10.1016/j.jcmg.2018.01.004)

Puntmann, V. O., Valbuena, S., Hinojar, R., Petersen, S. E., Greenwood, J. P., Kramer, C. M., Kwong, R. Y., McCann, G. P., Berry, C., Nagel, E. (2018) Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification. Journal of Cardiovascular Magnetic Resonance, 20, (doi: 10.1186/s12968-018-0484-5)

Shah, A. S.V. et al. (2018) High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial. Lancet, 392, pp. 919-928. (doi: 10.1016/S0140-6736(18)31923-8)

The SCOT-HEART Investigators, et al. (2018) Coronary CT angiography and 5-year risk of myocardial infarction. New England Journal of Medicine, 379, pp. 924-933. (doi: 10.1056/NEJMoa1805971)

Corcoran, D., Young, R., Adlam, D., McConnachie, A., Mangion, K., Ripley, D., Cairns, D., Brown, J., Bucciarelli-Ducci, C., Baumbach, A., Kharbanda, R., Oldroyd, K. G., McCann, G. P., Greenwood, J. P., Berry, C. (2018) Coronary microvascular dysfunction in patients with stable coronary artery disease: the CE-MARC 2 coronary physiology sub-study. International Journal of Cardiology, 266, pp. 7-14. (doi: 10.1016/j.ijcard.2018.04.061)

Ravassa, S., Trippel, T., Bach, D., Bachran, D., González, A., López, B., Wachter, R., Hasenfuss, G., Delles, C., Dominiczak, A. F., Pieske, B., Díez, J., Edelmann, F. (2018) Biomarker-based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo-DHF trial. European Journal of Heart Failure, 20, pp. 1290-1299. (doi: 10.1002/ejhf.1194)

Carrick, D., Haig, C., Maznyczka, A. M., Carberry, J., Mangion, K., Ahmed, N., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Radjenovic, A., Welsh, P., Sattar, N., Wetherall, K., Oldroyd, K. G., Berry, C. (2018) Hypertension, microvascular pathology and prognosis after an acute myocardial infarction. Hypertension, 72, pp. 720-730. (doi: 10.1161/HYPERTENSIONAHA.117.10786)

McEntegart, M. B., Corcoran, D., Carrick, D., Clerfond, G., Sidik, N., Collison, D., Robertson, K. R., Shaukat, A., Watkins, S., Rocchicholi, P. R., Eteiba, H., Petrie, M. P., Lindsay, M. M., Oldroyd, K. G., Berry, C. (2018) Incidence of procedural myocardial infarction and cardiac magnetic resonance imaging-detected myocardial injury following percutaneous coronary intervention with rotational atherectomy. EuroIntervention, 14, pp. 819-823. (doi: 10.4244/EIJ-D-17-01077)

Kim, S. S., Yamamoto, M. H., Maehara, A., Sidik, N., Koyama, K., Berry, C., Oldroyd, K. G., Mintz, G. S., McEntegart, M. (2018) Intravascular ultrasound assessment of the effects of rotational atherectomy in calcified coronary artery lesions. International Journal of Cardiovascular Imaging, 34, pp. 1365-1371. (doi: 10.1007/s10554-018-1352-y)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2018) Persistent iron within the infarct core after ST-segment elevation myocardial infarction: implications for left ventricular remodeling and health outcomes. JACC: Cardiovascular Imaging, 11, pp. 1248-1256. (doi: 10.1016/j.jcmg.2017.08.027)

Kobayashi, Y., Lønborg, J., Jong, A., Nishi, T., De Bruyne, B., Høfsten, D. E., Kelbæk, H., Layland, J., Nam, C.-W., Pijls, N. H.J., Tonino, P. A.L., Warnøe, J., Oldroyd, K. G., Berry, C., Engstrøm, T., Fearon, W. F. (2018) Prognostic value of the residual SYNTAX score after functionally complete revascularization in ACS. Journal of the American College of Cardiology, 72, pp. 1321-1329. (doi: 10.1016/j.jacc.2018.06.069)

Divorty, N., Milligan, G., Graham, D., Nicklin, S. A. (2018) The orphan receptor GPR35 contributes to angiotensin II–induced hypertension and cardiac dysfunction in mice. American Journal of Hypertension, 31, pp. 1049-1058. (doi: 10.1093/ajh/hpy073)

Svanerud, J., Ahn, J.-M., Jeremias, A., van 't Veer, M., Gore, A., Maehara, A., Crowley, A., Pijls, N. H.J., De Bruyne, B., Johnson, N. P., Hennigan, B., Watkins, S., Berry, C., Oldroyd, K. G., Park, S.-J., Ali, Z. A. (2018) Validation of a novel non-hyperaemic index of coronary artery stenosis severity: the Resting Full-cycle Ratio (VALIDATE RFR) study. EuroIntervention, 14, pp. 806-814. (doi: 10.4244/EIJ-D-18-00342)

Ford, T. J., McEntegart, M., Berry, C., Oldroyd, K. G. (2018) Arterial access for invasive coronary angiography: the 'left backhander' Heart, Lung and Circulation, 27, pp. e98-e99. (doi: 10.1016/j.hlc.2018.02.021)

Gillis, K., Stevens, K. K., Bell, E., Patel, R. K., Jardine, A. G., Morris, S. T.W., Schneider, M. P., Delles, C., Mark, P. B. (2018) Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease. Clinical Kidney Journal, 11, pp. 532-539. (doi: 10.1093/ckj/sfx158)

Yew, S. N., Carrick, D., Corcoran, D., Ahmed, N., Carberry, J., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Oldroyd, K. G., Berry, C. (2018) Coronary thermodilution waveforms after acute reperfused ST‐segment–elevation myocardial infarction: relation to microvascular obstruction and prognosis. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.008957)

Shah, S. V., Zimmermann, F. M., Johnson, N. P., Nishi, T., Kobayashi, Y., Witt, N., Berry, C., Jeremias, A., Koo, B.-K., Esposito, G., Rioufol, G., Park, S.-J., Oldroyd, K. G., Barbato, E., Pijls, N. H.J., De Bruyne, B., Fearon, W. F. (2018) Sex differences in adenosine-free coronary pressure indexes: a CONTRAST substudy. JACC: Cardiovascular Interventions, 11, pp. 1454-1463. (doi: 10.1016/j.jcin.2018.03.030)

Ford, T. J., Corcoran, D., Sidik, N., McEntegart, M., Berry, C. (2018) Coronary microvascular dysfunction: Assessment of both structure and function. Journal of the American College of Cardiology, 72, pp. 584-586. (doi: 10.1016/j.jacc.2018.03.545)

Rajani, R. M., Quick, S., Ruigrok, S. R., Graham, D., Harris, S. E., Verhaaren, B. F.J., Fornage, M., Seshadri, S., Atanur, S. S., Dominiczak, A. F., Smith, C., Wardlaw, J. M., Williams, A. (2018) Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats. Science Translational Medicine, 10, (doi: 10.1126/scitranslmed.aam9507)

Daly, C. J. (2018) The future of education? Using 3D animation and virtual reality in teaching physiology. Physiology News, 111, pp. 43.

Findlay, I., Morris, T., Zhang, R., Mccowan, C., Shield, S., Forbes, B., McConnachie, A., Mangion, K., Berry, C. (2018) Linking hospital patient records for suspected or established acute coronary syndrome in a complex secondary care system: a proof-of-concept e-registry in NHS Scotland. European Heart Journal: Quality of Care and Clinical Outcomes, 4, pp. 155-167. (doi: 10.1093/ehjqcco/qcy007)

Morgan, H. L., Butler, E., Ritchie, S., Herse, F., Dechend, R., Beattie, E., McBride, M. W., Graham, D. (2018) Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats. Hypertension, 72, pp. 208-218. (doi: 10.1161/HYPERTENSIONAHA.118.10935)

Ford, T. J., Corcoran, D., Oldroyd, K. G., McEntegart, M., Rocchiccioli, P., Watkins, S., Brooksbank, K., Padmanabhan, S., Sattar, N., Briggs, A., McConnachie, A., Touyz, R., Berry, C. (2018) Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Angina (CorMicA) stratified medicine clinical trial. American Heart Journal, 201, pp. 86-94. (doi: 10.1016/j.ahj.2018.03.010)

De Lucca Camargo, L., Harvey, A. P., Rios, F. J., Tsiropoulou, S., Silva, R. D. N. d. O., Cao, Z., Graham, D., McMaster, C., Burchmore, R. J., Hartley, R. C., Bulleid, N., Montezano, A. C., Touyz, R. M. (2018) Vascular Nox (NADPH oxidase) compartmentalization, protein hyperoxidation, and endoplasmic reticulum stress response in hypertension. Hypertension, 72, pp. 235-246. (doi: 10.1161/HYPERTENSIONAHA.118.10824)

Bailey, E., McBride, M. W., McClure, J. D., Beattie, W., Graham, D., Dominiczak, A., Smith, C., Wardlaw, J. (2018) Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease. Clinical Science, 132, pp. 1315-1328. (doi: 10.1042/CS20171572)

Montezano, A. C., De Lucca Camargo, L., Persson, P., Rios, F. J., Harvey, A. P., Agnostopoulou, A., Palacios, R., Gandara, A. C. P., Alves-Lopes, R., Neves, K. B., Dulak-Lis, M., Holterman, C. E., Lagerblad de Oliveira, P., Graham, D., Kennedy, C., Touyz, R. M. (2018) NADPH oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.009388)

Ford, T. J., McCartney, P., Corcoran, D., Collison, D., Hennigan, B., McEntegart, M., Hildick-Smith, D., Oldroyd, K. G., Berry, C. (2018) Single versus two-stent strategies for coronary bifurcation lesions: a systematic review and meta-analysis of randomized trials with long-term follow-up. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.008730)

Montezano, A. C., De Lucca Camargo, L., Persson, P., Rios, F., Harvey, A., Anagnostopoulou, A., Palacios, R., Gandara, A. C. P., Alves‐Lopes, R., Neves, K., Dulak‐Lis, M., Holterman, C. E., de Oliveira, P. L., Graham, D., Kennedy, C., Touyz, R. (2018) NADPH Oxidase 5 is a pro‐contractile Nox isoform and a point of cross‐talk for calcium and redox signaling‐implications in vascular function. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.009388)

Corcoran, D., Ford, T. J., Hsu, L.-Y., Chiribiri, A., Orchard, V., Mangion, K., McEntegart, M., Rocchiccioli, P., Watkins, S., Good, R., Brooksbank, K., Padmanabhan, S., Sattar, N., McConnachie, A., Oldroyd, K. G., Touyz, R. M., Arai, A., Berry, C. (2018) Rationale and design of the Coronary Microvascular Angina Cardiac Magnetic Resonance imaging (CorCMR) diagnostic study: the CorMicA CMR sub-study. Open Heart, 5, (doi: 10.1136/openhrt-2018-000924)

Moreton, F. C., Cullen, B., Delles, C., Santosh, C., Lopez Gonzalez, R., Dani, K., Muir, K. W. (2018) Vasoreactivity in CADASIL: comparison to structural MRI and neuropsychology. Journal of Cerebral Blood Flow and Metabolism, 38, pp. 1085-1095. (doi: 10.1177/0271678X17710375)

Bulluck, H., Dharmakumar, R., Arai, A. E., Berry, C., Hausenloy, D. J. (2018) Cardiovascular magnetic resonance in acute ST-segment-elevation myocardial infarction: recent advances, controversies, and future directions. Circulation, 137, pp. 1949-1964. (doi: 10.1161/CIRCULATIONAHA.117.030693)

Lygirou, V., Latosinska, A., Makridakis, M., Mullen, W., Delles, C., Schanstra, J. P., Zoidakis, J., Pieske, B., Mischak, H., Vlahou, A. (2018) Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease. Journal of Translational Medicine, 16, (doi: 10.1186/s12967-018-1476-9)

Currie, G. E., von Scholten, B. J., Mary, S., Flores Guerrero, J.-L., Lindhardt, M., Reinhard, H., Jacobsen, P. K., Mullen, W., Parving, H.-H., Mischak, H., Rossing, P., Delles, C. (2018) Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria. Cardiovascular Diabetology, 17, (doi: 10.1186/s12933-018-0697-9)

Delles, C., Currie, G. (2018) Sex differences in hypertension and other cardiovascular diseases. Journal of Hypertension, 36, pp. 768-770. (doi: 10.1097/HJH.0000000000001655)

Mangion, K., Gao, H., Husmeier, D., Luo, X., Berry, C. (2018) Advances in computational modelling for personalised medicine after myocardial infarction. Heart, 104, pp. 550-557. (doi: 10.1136/heartjnl-2017-311449)

Delles, C., Rankin, N. J., Boachie, C., McConnachie, A., Ford, I., Kangas, A., Soininen, P., Trompet, S., Mooijaart, S. P., Jukema, J. W., Zannad, F., Ala-Korpela, M., Salomaa, V., Havulinna, A. S., Welsh, P., Würtz, P., Sattar, N. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi: 10.1002/ejhf.1076)

Horsburgh, K. et al. (2018) Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology. Clinical Science, 132, pp. 851-868. (doi: 10.1042/CS20171620)

Mancini, S. J., Boyd, D., Katwan, O. J., Strembitska, A., Almabrouk, T. A., Kennedy, S., Palmer, T. M., Salt, I. P. (2018) Canagliflozin inhibits interleukin-1β-stimulated cytokine and chemokine secretion in vascular endothelial cells by AMP-activated protein kinase-dependent and -independent mechanisms. Scientific Reports, 8, (doi: 10.1038/s41598-018-23420-4)

Lee, M. M.Y. et al. (2018) Non-Invasive Versus Invasive Management in Patients With Prior Coronary Artery Bypass Surgery With a Non-ST Segment Elevation Acute Coronary Syndrome: Comparisons Between the Randomized Controlled Pilot Trial and Registry. (doi: 10.1016/S0735-1097(18)30586-2)

Feng, Y.-M., Thijs, L., Zhang, Z.-Y., Yang, W.-Y., Huang, Q.-F., Wei, F.-F., Kuznetsova, T., Jennings, A.-M., Delles, C., Lennox, R., Verhamme, P., Dominiczak, A., Staessen, J. A. (2018) Glomerular function in relation to circulating adhesion molecules and inflammation markers in a general population. Nephrology Dialysis Transplantation, 33, pp. 426-435. (doi: 10.1093/ndt/gfx256)

Corcoran, D., Young, R., Cialdella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K.G., Berry, C. (2018) The effects of remote ischaemic preconditioning on coronary artery function in patients with stable coronary artery disease. International Journal of Cardiology, 252, pp. 24-30. (doi: 10.1016/j.ijcard.2017.10.082)

Currie, G., Delles, C. (2018) Blood pressure targets in the elderly. Journal of Hypertension, 36, pp. 234-236. (doi: 10.1097/HJH.0000000000001576)

Adamson, P. D., Hunter, A., Williams, M. C., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Dweck, M. R., Mills, N. L., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D. E. (2018) Diagnostic and prognostic benefits of computed tomography coronary angiography using the 2016 National Institute for Health and Care Excellence guidance within a randomised trial. Heart, 104, pp. 207-214. (doi: 10.1136/heartjnl-2017-311508)

Almabrouk, T. A.M., White, A. D., Ugusman, A. B., Skiba, D. S., Katwan, O. J., Alganga, H., Guzik, T. J., Touyz, R. M., Salt, I. P., Kennedy, S. (2018) High fat diet attenuates the anticontractile activity of aortic PVAT via a mechanism involving AMPK and reduced adiponectin secretion. Frontiers in Physiology, 9, (doi: 10.3389/fphys.2018.00051)

Adamson, P. D., Hunter, A., Madsen, D. M., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Williams, M. C., Berry, C., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., Timmis, A. D., van Beek, E. J.R., Dweck, M. R., Mickley, H., Mills, N. L., Newby, D. E. (2018) High-sensitivity cardiac troponin I and the diagnosis of coronary artery disease in patients with suspected angina pectoris. Circulation: Cardiovascular Quality and Outcomes, 11, (doi: 10.1161/CIRCOUTCOMES.117.004227)

Ford, T. J., Corcoran, D., Berry, C. (2018) Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need. Heart, 104, pp. 284-292. (doi: 10.1136/heartjnl-2017-311446)

McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)

Maznyczka, A. M., McCartney, P., Berry, C. (2018) Reference invasive tests of microvascular injury in myocardial infarction. BMJ Open, 104, pp. 90-92. (doi: 10.1136/heartjnl-2017-311695)

Lee, M. M.Y. et al. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial. (doi: 10.1136/heartjnl-2018-BCIS.9)

Souteyrand, G., Valladier, M., Amabile, N., Derimay, F., Harbaoui, B., Leddet, P., Barnay, P., Malcles, G., Mulliez, A., Berry, C., Eschalier, R., Combaret, N., Motreff, P. (2018) Diagnosis and management of spontaneously recanalized coronary thrombus guided by optical coherence tomography ― lessons from the French “Lotus Root” registry ― Circulation Journal, 82, pp. 783-790. (doi: 10.1253/circj.cj-17-0810)

Berry, C., Carberry, J., Mangion, K. (2018) How to mend a broken heart? JACC: Cardiovascular Imaging, 11, pp. 420-422. (doi: 10.1016/j.jcmg.2017.02.017)

Layland, J., Tong, D., Lee, M., Berry, C. (2018) ST and T-Wave Abnormality as Footprint of Myocardial Oedema in Non–ST-Elevation Myocardial Infarction. (doi: 10.1016/j.hlc.2018.06.515)

Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)

2017

Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C., Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)

Van't Veer, M., Pijls, N. H.J., Hennigan, B., Watkins, S., Ali, Z. A., De Bruyne, B., Zimmermann, F. M., van Nunen, L. X., Barbato, E., Berry, C., Oldroyd, K. G. (2017) Comparison of different diastolic resting indexes to iFR: are they all equal? Journal of the American College of Cardiology, 70, pp. 3088-3096. (doi: 10.1016/j.jacc.2017.10.066)

Ford, T. J., Berry, C., De Bruyne, B., Yong, A. C.S., Barlis, P., Fearon, W. F., Ng, M. K.C. (2017) Physiological predictors of acute coronary syndromes: emerging insights from the plaque to the vulnerable patient. JACC: Cardiovascular Interventions, 10, pp. 2539-2547. (doi: 10.1016/j.jcin.2017.08.059)

Berry, C., McClure, J. D., Oldroyd, K. G. (2017) Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution. Circulation, 136, pp. 2389-2391. (doi: 10.1161/CIRCULATIONAHA.117.030430)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)

O'Neill, D.G., Riddell, A., Church, D.B., Owen, L., Brodbelt, D.C., Hall, J.L. (2017) Urinary incontinence in bitches under primary veterinary care in England: prevalence and risk factors. Journal of Small Animal Practice, 58, pp. 685-693. (doi: 10.1111/jsap.12731)

Krochmal, M., Kontostathi, G., Magalhães, P., Makridakis, M., Klein, J., Husi, H., Leierer, J., Mayer, G., Bascands, J.-L., Denis, C., Zoidakis, J., Zürbig, P., Delles, C., Schanstra, J. P., Mischak, H., Vlahou, A. (2017) Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy. Scientific Reports, 7, (doi: 10.1038/s41598-017-15359-9)

Pontillo, C. et al. (2017) Prediction of chronic kidney disease stage 3 by CKD273, a urinary proteomic biomarker. Kidney International Reports, 2, pp. 1066-1075. (doi: 10.1016/j.ekir.2017.06.004)

Schmieder, R. E., Wagner, F., Mayr, M., Delles, C., Ott, C., Keicher, C., Hrabak-Paar, M., Heye, T., Aichner, S., Khder, Y., Yates, D., Albrecht, D., Langenickel, T., Freyhardt, P., Janka, R., Bremerich, J. (2017) The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study. European Heart Journal, 38, pp. 3308-3317. (doi: 10.1093/eurheartj/ehx525)

Rutherford, E., Mangion, K., Mccomb, C., Bell, E., Cockburn, S., Talle, M., Roditi, G., Welsh, P., Woodward, R., Radjenovic, A., Struthers, A. D., Jardine, A., Berry, C., Patel, R. K., Mark, P. B. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, (doi: 10.1038/s41598-017-14481-y)

Kobayashi, Y., Johnson, N. P., Zimmermann, F. M., Witt, N., Berry, C., Jeremias, A., Koo, B.-K., Esposito, G., Rioufol, G., Park, S.-J., Nishi, T., Choi, D.-H., Oldroyd, K. G., Barbato, E., Pijls, N. H. J., De Bruyne, B., Fearon, W. F. (2017) Agreement of the resting distal to aortic coronary pressure with the instantaneous wave-free ratio. Journal of the American College of Cardiology, 70, pp. 2105-2113. (doi: 10.1016/j.jacc.2017.08.049)

Nguyen, L. P., Al-Sawalha, N. A., Parra, S., Pokkunuri, I., Omoluabi, O., Okulate, A. A., Windham Li, E., Hazen, M., Gonzalez-Granado, J. M., Daly, C. J., McGrath, J. C., Tuvim, M. J., Knoll, B. J., Dickey, B. F., Bond, R. A. (2017) β2-Adrenoceptor signaling in airway epithelial cells promotes eosinophilic inflammation, mucous metaplasia, and airway contractility. Proceedings of the National Academy of Sciences of the United States of America, 114, pp. E9163-E9171. (doi: 10.1073/pnas.1710196114)

Gao, H., Mangion, K., Carrick, D., Husmeier, D., Luo, X., Berry, C. (2017) Estimating prognosis in patients with acute myocardial infarction using personalized computational heart models. Scientific Reports, 7, (doi: 10.1038/s41598-017-13635-2)

Kohli-Lynch, C.N., Boyd, K., Briggs, A., Delles, C. (2017) A Framework for the Cost-Effectiveness Analysis of Novel Biomarker Testing in Cardiovascular Disease. (doi: 10.1016/j.jval.2017.08.040)

Stevens, K., Denby, L., Patel, R. K., Mark, P. B., Kettlewell, S., Smith, G. L., Clancy, M. J., Delles, C., Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32, pp. 1617-1627. (doi: 10.1093/ndt/gfw252)

Almabrouk, T. A. M., Ugusman, A. B., Katwan, O. J., Salt, I. P., Kennedy, S. (2017) Deletion of AMPKα1 attenuates the anticontractile effect of perivascular adipose tissue (PVAT) and reduces adiponectin release. British Journal of Pharmacology, 174, pp. 3398-3410. (doi: 10.1111/bph.13633)

Nishi, T., Johnson, N. P., De Bruyne, B., Berry, C., Gould, K. L., Jeremias, A., Oldroyd, K. G., Kobayashi, Y., Choi, D.-H., Pijls, N. H.J., Fearon, W. F. (2017) Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve. Circulation: Cardiovascular Interventions, 10, (doi: 10.1161/CIRCINTERVENTIONS.117.004985)

Gao, H., Qi, N., Feng, L., Ma, X., Danton, M., Berry, C., Luo, X. (2017) Modelling mitral valvular dynamics–current trend and future directions. International Journal for Numerical Methods in Biomedical Engineering, 33, (doi: 10.1002/cnm.2858)

Kennedy, S., Salt, I. P. (2017) Molecular mechanisms regulating perivascular adipose tissue - potential pharmacological targets? British Journal of Pharmacology, 174, pp. 3385-3387. (doi: 10.1111/bph.13969)

Wu, J., Lawrence, C., Wadsworth, R. M., Kennedy, S. (2017) Perivascular mast cells promote neointimal elastin deposition and suppress chronic vein graft restenosis in hyperlipidaemic mice. Vessel Plus, 2017, pp. 137-144. (doi: 10.20517/2574-1209.2017.15)

Gao, H., Feng, L., Qi, N., Berry, C., Griffith, B. E., Luo, X. (2017) A coupled mitral valve - left ventricle model with fluid-structure interaction. Medical Engineering and Physics, 47, pp. 128-136. (doi: 10.1016/j.medengphy.2017.06.042)

Greig, F. H., Kennedy, S., Gibson, G., Ramos, J. W., Nixon, G. F. (2017) PEA-15 (phosphoprotein enriched in astrocytes 15) is a protective mediator in the vasculature and is regulated during neointimal hyperplasia. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.117.006936)

Krochmal, M., Cisek, K., Filip, S., Markoska, K., Orange, C., Zoidakis, J., Gakiopoulou, C., Spasovski, G., Mischak, H., Delles, C., Vlahou, A., Jankowski, J. (2017) Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. Scientific Reports, 7, (doi: 10.1038/s41598-017-09393-w)

Berry, C. (2017) Stable coronary syndromes: the case for consolidating the nomenclature of stable ischemic heart disease. Circulation, 136, pp. 437-439. (doi: 10.1161/CIRCULATIONAHA.117.028991)

Newby, D. et al. (2017) Aortic wall inflammation predicts abdominal aortic aneurysm expansion, rupture, and need for surgical repair. Circulation, 136, pp. 787-797. (doi: 10.1161/CIRCULATIONAHA.117.028433)

Currie, G., Delles, C. (2017) Healthy vascular ageing. Hypertension, 70, pp. 229-231. (doi: 10.1161/HYPERTENSIONAHA.117.09122)

Mangion, K., McComb, C., Auger, D. A., Epstein, F. H., Berry, C. (2017) Magnetic resonance imaging of myocardial strain after acute ST-segment-elevation myocardial infarction: a systematic review. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006498)

Small, H. Y., Cornelius, D. C., Guzik, T. J., Delles, C. (2017) Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy. Placenta, 56, pp. 59-64. (doi: 10.1016/j.placenta.2017.03.003)

Zhang, Z.‐Y., Ravassa, S., Nkuipou‐Kenfack, E., Yang, W.-Y., Kerr, S. M., Koeck, T., Campbell, A., Kuznetsova, T., Mischak, H., Padmanabhan, S., Dominiczak, A. F., Delles, C., Staessen, J. A. (2017) Novel urinary peptidomic classifier predicts incident heart failure. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.005432)

Gajjala, P. R., Jankowski, V., Heinze, G., Bilo, G., Zanchetti, A., Noels, H., Liehn, E., Perco, P., Schulz, A., Delles, C., Kork, F., Biessen, E., Narkiewicz, K., Kawecka-Jaszcz, K., Floege, J., Soranna, D., Zidek, W., Jankowski, J. (2017) Proteomic-biostatistic integrated approach for finding the underlying molecular determinants of hypertension in human plasma. Hypertension, 70, pp. 412-419. (doi: 10.1161/HYPERTENSIONAHA.116.08906)

Knez, J., Marrachelli, V. G., Cauwenberghs, N., Winckelmans, E., Zhang, Z., Thijs, L., Brguljan-Hitij, J., Plusquin, M., Delles, C., Monleon, D., Redón, J., Staessen, J. A., Nawrot, T. S., Kuznetsova, T. (2017) Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study. PLoS ONE, 12, (doi: 10.1371/journal.pone.0181036)

Patil, K. C., Daly, C. J. (2017) Nanotechnology-based α1-adrenoceptor/gpr55 biomarker assay: molecular prognostic test for aggressive prostate cancer on the horizon? Socrates Almanac, 2017, pp. 20-22.

Ford, T. J., Corcoran, D., Berry, C. (2017) Coronary artery disease: physiology and prognosis. European Heart Journal, 38, pp. 1990-1992. (doi: 10.1093/eurheartj/ehx226)

Gao, H., Aderhold, A., Mangion, K., Luo, X., Husmeier, D., Berry, C. (2017) Changes and classification in myocardial contractile function in the left ventricle following acute myocardial infarction. Journal of the Royal Society: Interface, 14, (doi: 10.1098/rsif.2017.0203)

Corcoran, D., Hennigan, B., Berry, C. (2017) Fractional flow reserve: a clinical perspective. International Journal of Cardiovascular Imaging, 33, pp. 961-974. (doi: 10.1007/s10554-017-1159-2)

Abu Bakar, H., Dunn, W. R., Daly, C., Ralevic, V. (2017) Sensory innervation of perivascular adipose tissue: a crucial role in artery vasodilatation and leptin release. Cardiovascular Research, 113, pp. 962-972. (doi: 10.1093/cvr/cvx062)

Williams, M. C., Hunter, A., Shah, A., Assi, V., Lewis, S., Mangion, K., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D. E. (2017) Symptoms and quality of life in patients with suspected angina undergoing CT coronary angiography: a randomised controlled trial. Heart, 103, pp. 995-1001. (doi: 10.1136/heartjnl-2016-310129)

Wang, D., Mohammad, M., Wang, Y., Tan, R., Murray, L. S., Ricardo, S., Dagher, H., van Agtmael, T., Savige, J. (2017) The chemical chaperone, PBA, reduces ER stress and autophagy and increases collagen IV α5 expression in cultured fibroblasts from men with X-linked Alport syndrome and missense mutations. Kidney International Reports, 2, pp. 739-748. (doi: 10.1016/j.ekir.2017.03.004)

Hennigan, B., Johnson, N., McClure, J., Corcoran, D., Watkins, S., Berry, C., Oldroyd, K. G. (2017) Validation of the "smart" minimum FFR Algorithm in an unselected all comer population of patients with intermediate coronary stenoses. International Journal of Cardiovascular Imaging, 33, pp. 991-997. (doi: 10.1007/s10554-017-1126-y)

Harvey, A. P., Montezano, A. C., Hood, K. Y., Lopes, R. A., Rios, F., Ceravolo, G., Graham, D., Touyz, R. M. (2017) Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis. Life Sciences, 179, pp. 110-119. (doi: 10.1016/j.lfs.2017.05.002)

Aetesam-ur-Rahman, M., Berry, C. (2017) Cardiovascular Diagnosis and Therapy (CDT) editorial: the Minimalist Immediate Mechanical Intervention study. Cardiovascular Diagnosis and Therapy, 7, pp. S73-S76. (doi: 10.21037/cdt.2017.01.13)

Lopez-Gordo, E., Doszpoly, A., Duffy, M. R., Coughlan, L., Bradshaw, A. C., White, K. M., Denby, L., Nicklin, S. A., Baker, A. H. (2017) Defining a novel role for the coxsackie and adenovirus receptor in human adenovirus serotype 5 transduction in vitro in the presence of mouse serum. Journal of Virology, 91, (doi: 10.1128/JVI.02487-16)

Neisius, U., Olson, E., Rossi, S. H., Ibrahim, H. A., Currie, G., Dominiczak, A., Delles, C. (2017) Evaluation of the systemic micro- and macrovasculature in stable angina: a case-control study. PLoS ONE, 12, (doi: 10.1371/journal.pone.0178412)

Mary, S., Small, H. Y., Siwy, J., Mullen, W., Giri, A., Delles, C. (2017) Polymerization-incompetent uromodulin in the pregnant stroke-prone spontaneously hypertensive rat. Hypertension, 69, pp. 910-918. (doi: 10.1161/HYPERTENSIONAHA.116.08826)

Jacobs, L., Efremov, L., Ferreira, J. P., Thijis, L., Yang, W.-Y., Zhang, Z.-Y., Latini, R., Masson, S., Agabiti, N., Sever, P., Delles, C., Sattar, N., Butler, J., Cleland, J., Kuznetsova, T., Staessen, J. A., Zannad, F. (2017) Risk for incident heart failure: a subject-level meta-analysis from the Heart “OMics” in AGEing (HOMAGE) study. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.005231)

Singh, A., Greenwood, J. P., Berry, C., Dawson, D. K., Hogrefe, K., Kelly, D. J., Dhakshinamurthy, V., Lang, C. C.,, Khoo, J. P., Sprigings, D., Steeds, R. P., Jerosch-Herold, M., Neubauer, S., Prendergast, B., Williams, B., Zhang, R., Hudson, I., Squire, I. B., Ford, I., Samani, N. J., McCann, G. P. (2017) Comparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) study. European Heart Journal, 38, pp. 1222-1229. (doi: 10.1093/eurheartj/ehx001)

Layland, J., Rauhalammi, S., Lee, M. M.Y., Ahmed, N., Carberry, J., Teng Yue May, V., Watkins, S., McComb, C., Mangion, K., McClure, J. D., Carrick, D., O'Donnell, A., Sood, A., McEntegart, M., Oldroyd, K. G., Radjenovic, A., Berry, C. (2017) Diagnostic accuracy of 3.0-T magnetic resonance T1 and T2 mapping and T2-weighted dark-blood imaging for the infarct-related coronary artery in Non-ST-segment elevation myocardial infarction. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.004759)

Wilson, S. J., Newby, D. E., Dawson, D., Irving, J., Berry, C. (2017) Duration of dual antiplatelet therapy in acute coronary syndrome. Heart, 103, pp. 573-580. (doi: 10.1136/heartjnl-2016-309871)

Dominiczak, A., Delles, C., Padmanabhan, S. (2017) Genomics and precision medicine for clinicians and scientists in hypertension. Hypertension, 69, pp. e10-e13. (doi: 10.1161/HYPERTENSIONAHA.116.08252)

Layland, J. J., Carberry, J., May, V. T.Y., Lee, M., Eteiba, H., Lindsay, M., Petrie, M., McEntegart, M., Watkins, S., Shaukat, A., Oldroyd, K., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Hannah, A., Stewart, A., Henderson, R., McConnachie, A., Berry, C. (2017) Decision Making Using Fractional Flow Reserve is Associated With Lower Rates of Incomplete Revascularization Compared With Angiographic Guided Decision Making Amongst Patients With NSTEMI. (doi: 10.1016/s0735-1097(17)34446-7)

Htun, N. M., Magliano, D. J., Zhang, Z.-Y., Lyons, J., Petit, T., Nkuipou-Kenfack, E., Ramirez-Torres, A., von zur Muhlen, C., Maahs, D., Schanstra, J. P., Pontillo, C., Pejchinovski, M., Snell-Bergeon, J. K., Delles, C., Mischak, H., Staessen, J. A., Shaw, J. E., Koeck, T., Peter, K. (2017) Prediction of acute coronary syndromes by urinary proteome analysis. PLoS ONE, 12, (doi: 10.1371/journal.pone.0172036)

Small, H. Y., Akehurst, C., Sharafetdinova, L., McBride, M. W., McClure, J. D., Robinson, S. W., Carty, D. M., Freeman, D. J., Delles, C. (2017) HLA gene expression is altered in whole blood and placenta from women who later developed preeclampsia. Physiological Genomics, 49, pp. 193-200. (doi: 10.1152/physiolgenomics.00106.2016)

Currie, G., Delles, C. (2017) The future of "omics" in hypertension. Canadian Journal of Cardiology, 33, pp. 601-610. (doi: 10.1016/j.cjca.2016.11.023)

Carty, D. M., Doogan, F., Welsh, P., Dominiczak, A. F., Delles, C. (2017) Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, pp. 366-369. (doi: 10.1016/j.ejogrb.2017.01.048)

Graham-Brown, M. P.M., Rutherford, E., Levelt, E., March, D. S., Churchward, D. R., Stensel, D. J., McComb, C., Mangion, K., Cockburn, S., Berry, C., Moon, J. C., Mark, P. B., Burton, J. O., McCann, G. P. (2017) Native T1 mapping: inter-study, inter-observer and inter-center reproducibility in hemodialysis patients. Journal of Cardiovascular Magnetic Resonance, 19, (doi: 10.1186/s12968-017-0337-7)

Koh-Tan, H.H. C., Dashti, M., Wang, T., Beattie, W., Mcclure, J., Young, B., Dominiczak, A. F., McBride, M. W., Graham, D. (2017) Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3. Journal of Hypertension, 35, pp. 319-329. (doi: 10.1097/HJH.0000000000001155)

Delles, C., Husi, H. (2017) Systems biology approach in hypertension research. Springer

Tsiropoulou, S., McBride, M., Padmanabhan, S. (2017) Urine metabolomics in hypertension research. Springer

Mancini, S. J., White, A. D., Bijland, S., Rutherford, C., Graham, D., Richter, E. A., Viollet, B., Touyz, R. M., Palmer, T. M., Salt, I. P. (2017) Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptorassociated kinase-4 phosphorylation. Molecular and Cellular Endocrinology, 440, pp. 44-56. (doi: 10.1016/j.mce.2016.11.010)

Gebhard, C., Rhéaume, E., Berry, C., Brand, G., Kernaleguen, A.-E., Théberge-Julien, G., Alam, M. A., Lee, C. Y.W., Boileau, L., Chabot-Blanchet, M., Guertin, M.-C., Lavoie, M.-A., Grégoire, J., Ibrahim, R., L'Allier, P., Tardif, J.-C. (2017) Beneficial effects of reconstituted high-density lipoprotein (rHDL) on circulating CD34+ cells in patients after an acute coronary syndrome. PLoS ONE, 12, (doi: 10.1371/journal.pone.0168448)

Houston, S. A., Ugusman, A., Gnanadesika, S., Kennedy, S. (2017) An investigation of the antiplatelet effects of succinobucol (AGI-1067) Platelets, 28, pp. 295-300. (doi: 10.1080/09537104.2016.1218456)

Ewart, M.-A., Ugusman, A., Vishwanath, A., Almabrouk, T. A.M., Alganga, H. S.F., Katwan, O. J., Hubanova, P., Currie, S., Kennedy, S. (2017) Changes in IP3 receptor expression and function in aortic smooth muscle of atherosclerotic mice. Journal of Vascular Research, 54, pp. 68-78. (doi: 10.1159/000461581)

Delles, C., Vanholder, R. (2017) Chronic kidney disease. Clinical Science, 131, pp. 225-226. (doi: 10.1042/CS20160624)

McGinty, S., McCormick, C., McKittrick, C., Kennedy, S., Oldroyd, K., Wheel, M., Scullion, B., Pontrelli, G., McKee, S. (2017) Combining Mathematical Modelling with In-Vitro Experiments to Predict In-Vivo Drug-Eluting Stent Kinetics.

2016

Fattah, C., Nather, K., McCarroll, C. S., Hortigon-Vinagre, M. P., Zamora Rodriguez, V., Flores-Munoz, M., McArthur, L., Zentilin, L., Giacca, M., Touyz, R. M., Smith, G. L., Loughrey, C. M., Nicklin, S. A. (2016) Gene therapy with Angiotensin-(1-9) preserves left ventricular systolic function after myocardial infarction. Journal of the American College of Cardiology, 68, pp. 2652-2666. (doi: 10.1016/j.jacc.2016.09.946)

Mangion, K., Gao, H., Mccomb, C., Carrick, D., Clerfond, G., Zhong, X., Luo, X., Haig, C., Berry, C. (2016) A novel method for estimating myocardial strain: assessment of deformation tracking against reference magnetic resonance methods in healthy volunteers. Scientific Reports, 6, (doi: 10.1038/srep38774)

Kobayashi, Y., Johnson, N. P., Berry, C., De Bruyne, B., Gould, K. L., Jeremias, A., Oldroyd, K. G., Pijls, N. H.J., Fearon, W. F. (2016) The influence of lesion location on the diagnostic accuracy of adenosine-free coronary pressure wire measurements. JACC: Cardiovascular Interventions, 9, pp. 2390-2399. (doi: 10.1016/j.jcin.2016.08.041)

Carrick, D., Haig, C., Ahmed, N., Carberry, J., Teng Yue May, V., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davies, A., Abouzaid, A. M., Mordi, I., Ford, I., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment elevation myocardial infarction. Circulation, 134, pp. 1833-1847. (doi: 10.1161/CIRCULATIONAHA.116.022603)

Nicklin, S. A. (2016) A novel mechanism of action for angiotensin-(1-7) via the angiotensin type 1 receptor. Hypertension, 68, pp. 1342-1343. (doi: 10.1161/HYPERTENSIONAHA.116.08215)

Nagaraja, V., Ooi, S.-Y., Nolan, J., Large, A., De Belder, M., Ludman, P., Bagur, R., Curzen, N., Matsukage, T., Yoshimachi, F., Kwok, C. S., Berry, C., Mamas, M. A. (2016) Impact of incomplete percutaneous revascularization in patients With multivessel coronary artery disease: a systematic review and meta-analysis. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.116.004598)

Napp, A. E. et al. (2016) Computed tomography versus invasive coronary angiography: design and methods of the pragmatic randomised multicentre DISCHARGE trial. European Radiology, 27, pp. 2957-2968. (doi: 10.1007/s00330-016-4620-z)

Verdura, E., Hervé, D., Bergametti, F., Jacquet, C., Morvan, T., Prieto-Morin, C., Mackowiak, A., Manchon, E., Hosseini, H., Cordonnier, C., Girard-Buttaz, I., Rosenstingl, S., Hagel, C., Kuhlenbaümer, G., Leca-Radu, E., Goux, D., Fleming, L., Van Agtmael, T., Chabriat, H., Chapon, F., Tournier-Lasserve, E. (2016) Disruption of a miR-29 binding site leading to COL4A1 upregulation causes pontine autosomal dominant microangiopathy with leukoencephalopathy. Annals of Neurology, 80, pp. 741-753. (doi: 10.1002/ana.24782)

Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J.V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Rocca, H. P. B.-L., Delles, C., Heymans, S., Sattar, N., Jukema, J. W., Cleland, J. G.F., Zannad, F., Rossignol, P. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, (doi: 10.1186/s12916-016-0731-2)

Rutherford, C., Speirs, C., Williams, J. J.L., Ewart, M.-A., Mancini, S. J., Hawley, S. A., Delles, C., Viollet, B., Costa-Pereira, A. P., Baillie, G. S., Salt, I. P., Palmer, T. M. (2016) Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling. Science Signaling, 9, (doi: 10.1126/scisignal.aaf8566)

Hennigan, B., Oldroyd, K. G., Berry, C., Johnson, N., McClure, J., McCartney, P., McEntegart, M. B., Eteiba, H., Petrie, M. C., Rocchiccioli, P., Good, R., Lindsay, M. M., Hood, S., Watkins, S. (2016) Discordance between resting and hyperemic indices of coronary stenosis severity: the VERIFY 2 study (a comparative study of resting coronary pressure gradient, instantaneous wave-free ratio and fractional flow reserve in an unselected population referred for invasive angiography) Circulation: Cardiovascular Interventions, 9, (doi: 10.1161/CIRCINTERVENTIONS.116.004016)

Sirker, A., Kwok, C. S., Kotronias, R., Bagur, R., Bertrand, O., Butler, R., Berry, C., Nolan, J., Oldroyd, K., Mamas, M. (2016) Influence of access site choice for cardiac catheterization on risk of adverse neurological events: A systematic review and meta-analysis. American Heart Journal, 181, pp. 107-119. (doi: 10.1016/j.ahj.2016.06.027)

Mangion, K., Clerfond, G., Mccomb, C., Carrick, D., Rauhalammi, S. M., McClure, J., Corcoran, D. S., Woodward, R., Orchard, V., Radjenovic, A., Zhong, X., Berry, C. (2016) Myocardial strain in healthy adults across a broad age range as revealed by cardiac magnetic resonance imaging at 1.5 and 3.0T: associations of myocardial strain with myocardial region, age, and sex. Journal of Magnetic Resonance Imaging, 44, pp. 1197-1205. (doi: 10.1002/jmri.25280)

Ahmed, N., Carberry, J., Teng, V., Carrick, D., Berry, C. (2016) Risk assessment in patients with an acute ST-elevation myocardial infarction. Journal of Comparative Effectiveness Research, 5, pp. 581-593. (doi: 10.2217/cer-2016-0017)

Small, H. Y., Nosalski, R., Morgan, H., Beattie, E., Guzik, T., Graham, D., Delles, C. (2016) The role of tumor necrosis factor-α and natural killer cells in uterine artery function and pregnancy outcome in the stroke prone spontaneously hypertensive rat. Hypertension, 68, pp. 1298-1307. (doi: 10.1161/HYPERTENSIONAHA.116.07933)

Currie, G., Delles, C. (2016) Urinary proteomics for diagnosis and monitoring of diabetic nephropathy. Current Diabetes Reports, 16, (doi: 10.1007/s11892-016-0798-3)

Corcoran, D., Mangion, K., Berry, C. (2016) Clinical trials for the diagnosis and management of stable ischaemic heart disease: context, status and future implications. European Medical Journal Cardiology, 4, pp. 112-121.

Rutherford, E., Talle, M. A., Mangion, K., Bell, E., Rauhalammi, S. M., Roditi, G., McComb, C., Radjenovic, A., Welsh, P., Woodward, R., Struthers, A. D., Jardine, A. G., Patel, R. K., Berry, C., Mark, P. B. (2016) Definition of myocardial tissue abnormalities in end stage renal failure with cardiac magnetic resonance imaging using T1 mapping. Kidney International, 90, pp. 845-852. (doi: 10.1016/j.kint.2016.06.014)

Currie, G., Matt, P., Delles, C. (2016) Clinical cardiovascular proteomics. Springer

Greenwood, J. P., Ripley, D. P., Berry, C., McCann, G. P., Plein, S., Bucciarelli-Ducci, C., Dall’Armellina, E., Prasad, A., Bijsterveld, P., Foley, J. R., Mangion, K., Sculpher, M., Walker, S., Everett, C. C., Cairns, D. A., Sharples, L. D., Brown, J. M. (2016) Effect of care guided by cardiovascular magnetic resonance, myocardial perfusion scintigraphy, or NICE guidelines on subsequent unnecessary angiography rates: the CE-MARC 2 randomized clinical trial. JAMA: Journal of the American Medical Association, 316, pp. 1051-1060. (doi: 10.1001/jama.2016.12680)

Currie, G., Taylor, A. H.M., Fujita, T., Ohtsu, H., Lindhart, M., Rossing, P., Boesby, L., Edwards, N. C., Ferro, C. J., Townend, J. N., van den Meiracker, A. H., Saklayen, M. G., Oveisi, S., Jardine, A. G., Delles, C., Preiss, D. J., Mark, P. B. (2016) Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis. BMC Nephrology, 17, (doi: 10.1186/s12882-016-0337-0)

Rauhalammi, S. M.O., Mangion, K., Barrientos, P. H., Carrick, D. J.A., Clerfond, G., McClure, J., McComb, C., Radjenovic, A., Berry, C. (2016) Native myocardial longitudinal (T1) relaxation time: Regional, age, and sex associations in the healthy adult heart. Journal of Magnetic Resonance Imaging, 44, pp. 541-548. (doi: 10.1002/jmri.25217)

Morgan, H., Small, H.Y., Beattie, E., McBride, M.W., Graham, D. (2016) [OP.5D.02] Transcriptomic changes in early pregnancy-associated uterine artery remodelling in stroke prone spontaneously hypertensive rat. Journal of Hypertension, 34, pp. e63-e63. (doi: 10.1097/01.hjh.0000491501.79443.05)

Carberry, J., Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Remote zone extracellular volume and left ventricular remodeling in survivors of st-elevation myocardial infarction. Hypertension, 68, pp. 385-391. (doi: 10.1161/HYPERTENSIONAHA.116.07222)

Robertson, S., Parker, A. L., Clarke, C., Duffy, M. R., Alba, R., Nicklin, S. A., Baker, A. H. (2016) Retargeting FX binding-ablated HAdV-5 to vascular cells by inclusion of the RGD-4C peptide in hexon hypervariable region 7 and the HI loop. Journal of General Virology, 97, pp. 1911-1916. (doi: 10.1099/jgv.0.000505)

MacRitchie, N., Volpert, G., Al Washih, M., Watson, D. G., Futerman, A. H., Kennedy, S., Pyne, S., Pyne, N. J. (2016) Effect of the sphingosine kinase 1 selective inhibitor, PF-543 on arterial and cardiac remodelling in a hypoxic model of pulmonary arterial hypertension. Cellular Signalling, 28, pp. 946-955. (doi: 10.1016/j.cellsig.2016.03.014)

Mordi, I., Mordi, N., Delles, C., Tzemos, N. (2016) Endothelial dysfunction in human essential hypertension. Journal of Hypertension, 34, pp. 1464-1472. (doi: 10.1097/hjh.0000000000000965)

Mangion, K., Berry, C. (2016) Advances in magnetic resonance imaging of the myocardial area at risk and salvage. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/circimaging.116.005127)

Daly, C., Bulloch, J., Aidulis, D., Ma, M. (2016) The Design of Animations and Multimedia for Teaching.

Duffy, M.R., Doszpoly, A., Turner, G., Nicklin, S.A., Baker, A.H. (2016) The relevance of coagulation factor X protection of adenoviruses in human sera. Gene Therapy, 23, pp. 592-596. (doi: 10.1038/gt.2016.32)

Currie, G., Delles, C. (2016) Use of biomarkers in the evaluation and treatment of hypertensive patients. Current Hypertension Reports, 18, (doi: 10.1007/s11906-016-0661-6)

Daly, C.J., Bulloch, J.M., Ma, M., Aidulis, D. (2016) A comparison of animated versus static images in an instructional multimedia presentation. Advances in Physiology Education, 40, pp. 201-205. (doi: 10.1152/advan.00053.2015)

Berry, C., Poppe, K.K., Gamble, G.D., Earle, N.J., Ezekowitz, J.A., Squire, I.B., McMurray, J.J.V., McAlister, F.A., Komajda, M., Swedberg, K., Maggioni, A.P., Ahmed, A., Whalley, G.A., Doughty, R.N., Tarantini, L. (2016) Prognostic significance of anaemia in patients with heart failure with preserved and reduced ejection fraction: results from the MAGGIC individual patient data meta-analysis. QJM: An International Journal of Medicine, 109, pp. 377-382. (doi: 10.1093/qjmed/hcv087)

McCormick, C., Jones, R. L., Wadsworth, R. M., Mullen, A. B., Kennedy, S. (2016) A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery. Pharmacology and Pharmacy, 7, pp. 226-235. (doi: 10.4236/pp.2016.76029)

Myint, P. K., Kwok, C. S., Roffe, C., Kontopantelis, E., Zaman, A., Berry, C., Ludman, P. F., de Belder, M. A., Mamas, M. A. (2016) Determinants and outcomes of stroke following percutaneous coronary intervention by indication. Stroke, 47, pp. 1500-1507. (doi: 10.1161/STROKEAHA.116.012700)

Ballantyne, M. D., Pinel, K., Dakin, R., Vesey, A. T., Diver, L., MacKenzie, R., Garcia, R., Welsh, P., Sattar, N., Hamilton, G., Joshi, N., Dweck, M. R., Miano, J. M., McBride, M. W., Newby, D. E., McDonald, R. A., Baker, A. H. (2016) Smooth muscle enriched long noncoding RNA (SMILR) regulates cell proliferation. Circulation, 133, pp. 2050-2065. (doi: 10.1161/circulationaha.115.021019)

Carrick, D., Haig, C., Carberry, J., Teng Tue May, V., Mccartney, P., Welsh, P., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Mahrous, A., Rauhalammi, S. M.O., Mordi, I., Ford, I., Radjenovic, A., Sattar, N., Oldroyd, K. G., Berry, C. (2016) Microvascular resistance of the culprit coronary artery in acute ST-elevation myocardial infarction. JCI Insight, 1, (doi: 10.1172/jci.insight.85768)

Johnson, N. P. et al. (2016) Continuum of vasodilator stress from rest to contrast medium to adenosine hyperemia for fractional flow reserve assessment. JACC: Cardiovascular Interventions, 9, pp. 757-767. (doi: 10.1016/j.jcin.2015.12.273)

Lee, M. M.Y., Petrie, M. C., Rocchiccioli, P., Simpson, J., Jackson, C., Brown, A., Corcoran, D., Mangion, K., McEntegart, M., Shaukat, A., Rae, A., Hood, S., Peat, E., Findlay, I., Murphy, C., Cormack, A., Bukov, N., Balachandran, K., Papworth, R., Ford, I., Briggs, A., Berry, C. (2016) Non-invasive versus invasive management in patients with prior coronary artery bypass surgery with a non-ST segment elevation acute coronary syndrome: study design of the pilot randomised controlled trial and registry (CABG-ACS) Open Heart, 3, (doi: 10.1136/openhrt-2015-000371)

Williams, M. C., Hunter, A., Shah, A. S.V., Assi, V., Lewis, S., Smith, J., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D. E. (2016) Use of coronary computed tomographic angiography to guide management of patients with coronary disease. Journal of the American College of Cardiology, 67, pp. 1759-1768. (doi: 10.1016/j.jacc.2016.02.026)

Berry, C., Carrick, D., Haig, C., Oldroyd, K. G. (2016) “Waves of Edema” seem implausible. Journal of the American College of Cardiology, 67, pp. 1868-1869. (doi: 10.1016/j.jacc.2015.11.073)

Wan Sulaiman, W.N., Caslake, M.J., Delles, C., Karlsson, H., Mulder, M.T., Graham, D., Freeman, D.J. (2016) Does high-density lipoprotein protect vascular function in healthy pregnancy? Clinical Science, 130, pp. 491-497. (doi: 10.1042/cs20150475)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Lindsay, M., Mahrous, A., Ford, I., Tzemos, N., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Prognostic significance of infarct core pathology revealed by quantitative non-contrast in comparison to contrast cardiac magnetic resonance imaging in reperfused ST-elevation myocardial infarction survivors. European Heart Journal, 37, pp. 1044-1059. (doi: 10.1093/eurheartj/ehv372)

Eisele, N., Albrecht, C., Mistry, H. D., Dick, B., Baumann, M., Surbek, D., Currie, G., Delles, C., Mohaupt, M. G., Escher, G., Gennari-Moser, C. (2016) Placental expression of the angiogenic placental growth factor is stimulated by both aldosterone and simulated starvation. Placenta, 40, pp. 18-24. (doi: 10.1016/j.placenta.2016.02.004)

Neisius, U., Koeck, T., Mischak, H., Rossi, S. H., Olson, E., Carty, D. M., Dymott, J. A., Dominiczak, A. F., Berry, C., Oldroyd, K. G., Delles, C. (2016) Urine proteomics in the diagnosis of stable angina. BMC Cardiovascular Disorders, 16, (doi: 10.1186/s12872-016-0246-y)

Durussel, J., Haile, D., Mooses, K., Daskalaki, E., Beattie, W., Mooses, M., Mekonen, W., Ongaro, N., Anjila, E., Patel, R., Padmanabhan, N., McBride, M., McClure, J., Pitsiladis, Y. (2016) Blood transcriptional signature of recombinant human erythropoietin administration and implications for antidoping strategies. Physiological Genomics, 48, pp. 202-209. (doi: 10.1152/physiolgenomics.00108.2015)

Mullan, A., Delles, C., Ferrell, W., Mullen, W., Edwards, C. A., McColl, J. H., Roberts, S. A., Lean, M. (2016) Effects of a beverage rich in (poly)phenols on established and novel risk markers for vascular disease in medically uncomplicated overweight or obese subjects: A four week randomized trial. Atherosclerosis, 246, pp. 169-176. (doi: 10.1016/j.atherosclerosis.2016.01.004)

Wilson, R., Aung, H., Ju, X., Paterson, C., Sayer, R., McIntyre, A., Going, J., Irvine, R., Berry, C. (2016) Optical coherence tomography: an experimental validation for vascular imaging of saphenous vein bypass grafts. Biomedical Physics and Engineering Express, 2, (doi: 10.1088/2057-1976/2/2/025002)

Chouchani, E. T., Pell, V. R., James, A. M., Work, L. M., Saeb-Parsy, K., Frezza, C., Krieg, T., Murphy, M. P. (2016) A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury. Cell Metabolism, 23, pp. 254-263. (doi: 10.1016/j.cmet.2015.12.009)

Currie, G., Delles, C., Touyz, R. M., Staessen, J. A., Dominiczak, A. F., Jennings, G. L. R., Wang, J.-G. (2016) A woman with treatment-resistant hypertension. Hypertension, 67, pp. 243-250. (doi: 10.1161/HYPERTENSIONAHA.115.06756)

Jones, F. E., Bailey, M. A., Murray, L. S., Lu, Y., McNeilly, S., Schlötzer-Schrehardt, U., Lennon, R., Sado, Y., Brownstein, D. G., Mullins, J. J., Kadler, K. E., Van Agtmael, T. (2016) ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice. Disease Models and Mechanisms, 9, pp. 165-76. (doi: 10.1242/dmm.021741)

McKittrick, C.M., Kennedy, S., Oldroyd, K.G., Mcginty, S., McCormick, C. (2016) Modelling the impact of atherosclerosis on drug release and distribution from coronary stents. Annals of Biomedical Engineering, 44, pp. 477-487. (doi: 10.1007/s10439-015-1456-7)

Small, H. Y., Currie, G. E., Delles, C. (2016) Prostasin, proteases, and preeclampsia. Journal of Hypertension, 34, pp. 193-195. (doi: 10.1097/hjh.0000000000000828)

Carrick, D., Haig, C., Rauhalammi, S., Clerfond, G., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Mahrous, A., Welsh, P., Sattar, N., Ford, I., Oldroyd, K., Radjenovic, A., Berry, C. (2016) Temporal evolution of myocardial hemorrhage and edema in patients after acute ST-elevation myocardial infarction: pathophysiologic insights and clinical implications. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.115.002834)

Watt, J., Kennedy, S., Ahmed, N., Hayhurst, J., McClure, J. D., Berry, C., Wadsworth, R. M., Oldroyd, K. G. (2016) The relationship between oxidised LDL, endothelial progenitor cells and coronary endothelial function in patients with CHD. Open Heart, 3, (doi: 10.1136/openhrt-2015-000342)

Mangion, K., Gao, H., Radjenovic, A., Luo, X., Haig, C., Berry, C. (2016) Pixel-tracking derived strain using the GlasgowHeart Method. Journal of Cardiovascular Magnetic Resonance, 18, (doi: 10.1186/1532-429X-18-S1-P9)

Ahmed, N., Layland, J., Carrick, D., Petrie, M. C., McEntegart, M., Eteiba, H., Hood, S., Lindsay, M., Watkins, S., Davie, A., Mahrous, A., Carberry, J., Teng, V., McConnachie, A., Curzen, N., Oldroyd, K. G., Berry, C. (2016) Safety of guidewire-based measurement of fractional flow reserve and the index of microvascular resistance using intravenous adenosine in patients with acute or recent myocardial infarction. International Journal of Cardiology, 202, pp. 305-310. (doi: 10.1016/j.ijcard.2015.09.014)

Small, H. Y., Morgan, H., Beattie, E., Griffin, S., Indahl, M., Delles, C., Graham, D. (2016) Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. Placenta, 37, pp. 34-44. (doi: 10.1016/j.placenta.2015.10.022)

Olsen, M. H., Angell, S. Y., Asma, S., Boutouyrie, P., Burger, D., Chirinos, J. A., Damasceno, A., Delles, C., Gimenez-Roqueplo, A.-P., Hering, D., López-Jaramillo, P., Martinez, F., Perkovic, V., Rietzschel, E. R., Schillaci, G., Schutte, A. E., Scuteri, A., Sharman, J. E., Wachtell, K., Wang, J. G. (2016) A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension. Lancet, 388, pp. 2665-2712. (doi: 10.1016/S0140-6736(16)31134-5)

Boulberdaa, M., Scott, E., Ballantyne, M., Garcia, R., Descamps, B., Angelini, G. D., Brittan, M., Hunter, A., McBride, M., McClure, J., Miano, J. M., Emanueli, C., Mills, N. L., Mountford, J. C., Baker, A. H. (2016) A role for the long non-coding RNA SENCR in commitment and function of endothelial cells. Molecular Therapy, 24, pp. 978-990. (doi: 10.1038/mt.2016.41)

Zhang, Z.-y., Ravassa, S., Yang, W.-Y., Petit, T., Pejchinovski, M., Zürbig, P., López, B., Wei, F.-F., Pontillo, C., Thijs, L., Jacobs, L., González, A., Koeck, T., Delles, C., Voigt, J.-U., Verhamme, P., Kuznetsova, T., Díez, J., Mischak, H., Staessen, J. A. (2016) Diastolic left ventricular function in relation to urinary and serum collagen biomarkers in a general population. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167582)

McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C., Milligan, G., Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52, pp. 383-395. (doi: 10.1159/000444754)

Corcoran, D., Berry, C. (2016) How to measure myocardial infarct size by cardiac magnetic resonance imaging. Heart and Metabolism, 70, pp. 14-18.

Mangion, K., Carrick, D., Hennigan, B. W., Payne, A. R., McClure, J., Mason, M., Das, R., Wilson, R., Edwards, R. J., Petrie, M. C., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2016) Infarct size and left ventricular remodelling after preventive percutaneous coronary intervention. Heart, 102, pp. 1980-1987. (doi: 10.1136/heartjnl-2015-308660)

Carrick, D., Haig, C., Watkins, S., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Davie, A., Mahrous, A., Mordi, I., Rauhalammi, S., Sattar, N., Welsh, P., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/CIRCIMAGING.115.004148)

Mangion, K., Corcoran, D., Carrick, D., Berry, C. (2016) New perspectives on the role of cardiac magnetic resonance imaging to evaluate myocardial salvage and myocardial hemorrhage after acute reperfused ST-elevation myocardial infarction. Expert Review of Cardiovascular Therapy, 14, pp. 843-854. (doi: 10.1586/14779072.2016.1173544)

Gillis, K. A., Mccomb, C., Patel, R. K., Stevens, K. K., Schneider, M. P., Radjenovic, A., Morris, S. T.W., Roditi, G. H., Delles, C., Mark, P. B. (2016) Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease. Nephron, 133, pp. 183-192. (doi: 10.1159/000447601)

Lindhardt, M., Persson, F., Currie, G., Pontillo, C., Beige, J., Delles, C., von der Leyen, H., Mischak, H., Navis, G., Noutsou, M., Ortiz, A., Ruggenenti, P. L., Rychlik, I., Spasovski, G., Rossing, P. (2016) Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy in TYpe 2 diabetic patients with normoalbuminuria (PRIORITY): essential study design and rationale of a randomised clinical multicentre trial. BMJ Open, 6, (doi: 10.1136/bmjopen-2015-010310)

Sheikh, A. M., Small, H. Y., Currie, G., Delles, C. (2016) Systematic review of micro-RNA expression in pre-eclampsia identifies a number of common pathways associated with the disease. PLoS ONE, 11, (doi: 10.1371/journal.pone.0160808)

2015

Berry, C., Corcoran, D., Hennigan, B., Watkins, S., Layland, J., Oldroyd, K. G. (2015) Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments. European Heart Journal, 36, pp. 3155-3164. (doi: 10.1093/eurheartj/ehv206)

Nam, J., Briggs, A., Layland, J., Oldroyd, K. G., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Eteiba, H., Petrie, M. C., Lindsay, M., Watkins, S., Corbett, S., O'Rourke, B., O'Donnell, A., Stewart, A., Hannah, A., McConnachie, A., Henderson, R., Berry, C. (2015) Fractional flow reserve (FFR) versus angiography in guiding management to optimise outcomes in non-ST segment elevation myocardial infarction (FAMOUS-NSTEMI) developmental trial: cost-effectiveness using a mixed trial- and model-based methods. Cost Effectiveness and Resource Allocation, 2015, (doi: 10.1186/s12962-015-0045-9)

Gao, H., Li, W.G., Cai, L., Berry, C., Luo, X.Y. (2015) Parameter estimation in a Holzapfel–Ogden law for healthy myocardium. Journal of Engineering Mathematics, 95, pp. 231-248. (doi: 10.1007/s10665-014-9740-3)

Layland, J., Nerlekar, N., Palmer, S., Berry, C., Oldroyd, K. (2015) Invasive assessment of the coronary microcirculation in the catheter laboratory. International Journal of Cardiology, 199, pp. 141-149. (doi: 10.1016/j.ijcard.2015.05.190)

Aitken, E., Kerr, D., Geddes, C., Berry, C., Kingsmore, D. (2015) Cardiovascular changes occurring with occlusion of a mature arteriovenous fistula. Journal of Vascular Access, 16, pp. 459-466. (doi: 10.5301/jva.5000336)

Greig, F. H., Ewart, M.-A., McNaughton, E., Cooney, J., Spickett, C. M., Kennedy, S. (2015) The hypotensive effect of acute and chronic AMP-activated protein kinase activation in normal and hyperlipidemic mice. Vascular Pharmacology, 74, pp. 93-102. (doi: 10.1016/j.vph.2015.07.010)

Deng, L., Blanco Lopez, F. J., Stevens, H., Lu, R., Caudrillier, A., McBride, M., McClure, J. D., Grant, J., Thomas, M., Frid, M., Stenmark, K., White, K., Seto, A. G., Morrell, N. W., Bradshaw, A. C., MacLean, M. R., Baker, A. H. (2015) MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circulation Research, 117, pp. 870-883. (doi: 10.1161/CIRCRESAHA.115.306806)

Akehurst, C., Small, H., Sharafetdinova, L., Forrest, R., Beattie, W., Brown, C. E., Robinson, S. W., McClure, J. D., Work, L. M., Carty, D. M., McBride, M. W., Freeman, D. J., Delles, C. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33, pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656)

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892)

Corcoran, D., Grant, P., Berry, C. (2015) Risk stratification in non-ST elevation acute coronary syndromes: risk scores, biomarkers and clinical judgment. International Journal of Cardiology: Heart and Vasculature, 8, pp. 131-137. (doi: 10.1016/j.ijcha.2015.06.009)

Lindsey, M. L., Mayr, M., Gomes, A. V., Delles, C., Arrell, D. K., Murphy, A. M., Lange, R. A., Costello, C. E., Jin, Y.-F., Laskowitz, D. T., Sam, F., Terzic, A., Van Eyk, J., Srinivas, P. R. (2015) Transformative impact of proteomics on cardiovascular health and disease: a scientific statement from the American Heart Association. Circulation, 132, pp. 852-872. (doi: 10.1161/CIR.0000000000000226)

Mordi, I., Radjenovic, A., Stanton, T., Gardner, R., McPhaden, A., Carrick, D., Berry, C., Tzemos, N. (2015) Prevalence and prognostic significance of lipomatous metaplasia in poatients with prior myocardial infarction. JACC: Cardiovascular Imaging, 8, pp. 1111-1112. (doi: 10.1016/j.jcmg.2014.07.024)

Wu, J., Grassia, G., Cambrook, H., Ialenti, A., MacRitchie, N., Carberry, J., Wadsworth, R. M., Lawrence, C., Kennedy, S., Maffia, P. (2015) Perivascular mast cells regulate vein graft neointimal formation and remodeling. PeerJ, 3, (doi: 10.7717/peerj.1192)

McComb, C., Carrick, D., McClure, J. D., Woodward, R., Radjenovic, A., Foster, J. E., Berry, C. (2015) Assessment of the relationships between myocardial contractility and infarct tissue revealed by serial magnetic resonance imaging in patients with acute myocardial infarction. International Journal of Cardiovascular Imaging, 31, pp. 1201-1209. (doi: 10.1007/s10554-015-0678-y)

Schanstra, J.P. et al. (2015) Diagnosis and prediction of CKD progression by assessment of urinary peptides. Journal of the American Society of Nephrology, 26, pp. 1999-2010. (doi: 10.1681/asn.2014050423)

Menni, C. et al. (2015) Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate. Hypertension, 66, pp. 422-429. (doi: 10.1161/HYPERTENSIONAHA.115.05544)

Garg, S., Anderson, S.G., Oldroyd, K., Berry, C., Emdin, C.A., Peters, S.A.E., West, N.E.J., Kelly, D., Balachandran, K., McDonald, J., Singh, R., Devadathan, S., Redwood, S., Ludman, P.F., Rahimi, K., Woodward, M. (2015) Outcomes of percutaneous coronary intervention performed at offsite versus onsite surgical centers in the United Kingdom. Journal of the American College of Cardiology, 66, pp. 363-372. (doi: 10.1016/j.jacc.2015.05.052)

Mckinney, C.A., Kennedy, S., Baillie, G.S., Milligan, G., Nicklin, S.A. (2015) Angiotensin-(1-7) and angiotensin-(1-9) inhibit vascular smooth muscle cell growth and migration in vitro and vascular remodelling in vivo. Atherosclerosis, 241, pp. e44. (doi: 10.1016/j.atherosclerosis.2015.04.158)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Lindsay, M., Watkins, S., Hood, S., Davie, A., Marous, A., Sattar, N., Welsh, P., Tzemos, N., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2015) Pathophysiology of LV remodeling in survivors of STEMI : inflammation, remote myocardium, and prognosis. JACC: Cardiovascular Imaging, 8, pp. 779-789. (doi: 10.1016/j.jcmg.2015.03.007)

Johnson, N.P., Johnson, D.T., Kirkeeide, R.L., Berry, C., De Bruyne, B., Fearon, W.F., Oldroyd, K.G., Pijls, N.H.J., Gould, K.L. (2015) Repeatability of fractional flow reserve despite variations in systemic and coronary hemodynamics. JACC: Cardiovascular Interventions, 8, pp. 1018-1027. (doi: 10.1016/j.jcin.2015.01.039)

McDonald, R. A., Halliday, C. A., Miller, A. M., Diver, L. A., Dakin, R. S., Montgomery, J., McBride, M. W., Kennedy, S., McClure, J. D., Robertson, K. E., Douglas, G., Channon, K. M., Oldroyd, K., Baker, A. H. (2015) Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation. Journal of the American College of Cardiology, 65, pp. 2314-2327. (doi: 10.1016/j.jacc.2015.03.549)

McArthur, L., Chilton, L., Smith, G. L., Nicklin, S. A. (2015) Electrical consequences of cardiac myocyte: fibroblast coupling. Biochemical Society Transactions, 43, pp. 513-518. (doi: 10.1042/BST20150035)

Dakin, R. S., Parker, A. L., Delles, C., Nicklin, S. A., Baker, A. H. (2015) Efficient transduction of primary vascular cells by the rare adenovirus serotype 49 vector. Human Gene Therapy, 26, pp. 312-319. (doi: 10.1089/hum.2015.019)

Fox, C. S., Hall, J. L., Arnett, D. K., Ashley, E. A., Delles, C., Engler, M. B., Freeman, M. W., Johnson, J. A., Lanfear, D. E., Liggett, S. B., Lusis, A. J., Loscalzo, J., MacRae, C. A., Musunuru, K., Newby, L. K., O'Donnell, C. J., Rich, S. S., Terzic, A. (2015) Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation, 131, pp. 1715-1736. (doi: 10.1161/CIR.0000000000000211)

Greig, F. H., Hutchison, L., Spickett, C. M., Kennedy, S. (2015) Differential effects of chlorinated and oxidized phospholipids in vascular tissue: implications for neointima formation. Clinical Science, 128, pp. 579-592. (doi: 10.1042/CS20140578)

Nicklin, S. A., Griesenbach, U., Baker, A. H. (2015) Special focus issue on the annual meeting of the british society for gene and cell therapy. Human Gene Therapy, 26, pp. 247-248. (doi: 10.1089/hum.2015.2500)

Ravassa, S., Kuznetsova, T., Varo, N., Thijs, L., Delles, C., Dominiczak, A., Díez, J., Staessen, J. A. (2015) Biomarkers of cardiomyocyte injury and stress identify left atrial and left ventricular remodelling and dysfunction: a population-based study. International Journal of Cardiology, 185, pp. 177-185. (doi: 10.1016/j.ijcard.2015.03.046)

Rousset, C. I., Leiper, F. C., Kichev, A., Gressens, P., Carling, D., Hagberg, H., Thornton, C. (2015) A dual role for AMP-activated protein kinase (AMPK) during neonatal hypoxic-ischaemic brain injury in mice. Journal of Neurochemistry, 133, pp. 242-252. (doi: 10.1111/jnc.13034)

Patil, K. C., McPherson, L., Daly, C. J. (2015) Co-localization of alpha1-adrenoceptors and GPR55: a novel prostate cancer paradigm? Pharmacology and Pharmacy, 6, pp. 212-220. (doi: 10.4236/pp.2015.64023)

McInnes, I. B., Thompson, L., Giles, J. T., Bathon, J. M., Salmon, J. E., Beaulieu, A. D., Codding, C. E., Carlson, T. H., Delles, C., Lee, J. S., Sattar, N. (2015) Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study. Annals of the Rheumatic Diseases, 74, pp. 694-702. (doi: 10.1136/annrheumdis-2013-204345)

Mischak, H., Delles, C., Vlahou, A., Vanholder, R. (2015) Proteomic biomarkers in kidney disease: issues in development and implementation. Nature Reviews Nephrology, 11, pp. 221-232. (doi: 10.1038/nrneph.2014.247)

Rannikmäe, K. et al. (2015) Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease. Neurology, 84, pp. 918-926. (doi: 10.1212/WNL.0000000000001309)

Skogstrand, T., Leh, S., McClure, J., Dashti, M., Iversen, B. M., Graham, D., McBride, M., Hultström, M. (2015) Identification of a common molecular pathway in hypertensive renal damage. Journal of Hypertension, 33, pp. 584-596. (doi: 10.1097/HJH.0000000000000395)

Duffy, M., Ma, J., Deng, L., Dakin, R. S., Uil, T., Custers, J., Kelly, S. M., McVey, J. H., Nicklin, S. A., Baker, A. H. (2015) Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo. PLoS Pathogens, 11, (doi: 10.1371/journal.ppat.1004673)

Layland, J. et al. (2015) Fractional flow reserve vs. angiography in guiding management to optimize outcomes in non-ST-segment elevation myocardial infarction: the British Heart Foundation FAMOUS-NSTEMI randomized trial. European Heart Journal, 36, pp. 100-111. (doi: 10.1093/eurheartj/ehu338)

Ripley, D. P., Brown, J., Everett, C. C., Bijsterveld, P., Walker, S., Sculpher, M., McCann, G. P., Berry, C., Plein, S., Greenwood, J. P. (2015) Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease. American Heart Journal, 169, pp. 17-24.e1. (doi: 10.1016/j.ahj.2014.10.008)

Layland, J., Rauhalammi, S., Watkins, S., Ahmed, N., McClure, J., Lee, M. M.Y., Carrick, D., O’Donnell, A., Sood, A., Petrie, M. C., Teng Yue May, V., Eteiba, H., Lindsay, M., McEntegart, M., Oldroyd, K. G., Radjenovic, A., Berry, C. (2015) Assessment of fractional flow reserve in patients with recent Non–ST-Segment–Elevation Myocardial Infarction. Circulation: Cardiovascular Interventions, 8, (doi: 10.1161/circinterventions.114.002207)

Musunuru, K., Hickey, K. T., Al-Khatib, S. M., Delles, C., Fornage, M., Fox, C. S., Frazier, L., Gelb, B. D., Herrington, D. M., Lanfear, D. E., Rosand, J. (2015) Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. Circulation: Cardiovascular Genetics, 8, pp. 216-242. (doi: 10.1161/HCG.0000000000000020)

Newby, D. et al. (2015) CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial. Lancet, 385, pp. 2383-2391. (doi: 10.1016/S0140-6736(15)60291-4)

McGinty, S., Wheel, M., McKee, S., McCormick, C., McKittrick, C., Kennedy, S., Oldroyd, K. (2015) Can Anisotropy Enhance the Spatial Uniformity of Drug Distribution in Biological Tissue?

Corcoran, D., Berry, C., Oldroyd, K. (2015) Current frontiers in the clinical research of coronary physiology. Interventional Cardiology, 7, pp. 97-106.

Gao, H., Qi, N., Ma, X., Griffith, B. E., Berry, C., Luo, X. (2015) Fluid-structure interaction model of human mitral valve within left ventricle. Springer International Publishing

Divorty, N., Mackenzie, A., Nicklin, S., Milligan, G. (2015) G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease. Frontiers in Pharmacology, 6, (doi: 10.3389/fphar.2015.00041)

Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S., Porteous, D. J., Starr, J., Deary, I. J., Wardlaw, J. M. (2015) Genes from a translational analysis support a multifactorial nature of white matter hyperintensities. Stroke, 46, pp. 341-347. (doi: 10.1161/STROKEAHA.114.007649)

Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C., Currie, G., Schlembach, D., Mohaupt, M.G., Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, (doi: 10.1186/s12958-015-0100-6)

Gao, H., Berry, C., Luo, X. (2015) Image-derived human left ventricular modelling with fluid-structure interaction. Springer International Publishing

Aitken, E., Geddes, C., Thomson, P., Kasthuri, R., Chandramohan, M., Berry, C., Kingsmore, D. (2015) Immediate access arteriovenous grafts versus tunnelled central venous catheters: study protocol for a randomised controlled trial. Trials, 16, (doi: 10.1186/s13063-015-0556-x)

Mangion, K., Carrick, D., Payne, A., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K., Berry, C. (2015) Infarct burden following multivessel PCI vs. infarct-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O9)

Souteyrand, G., Amabile, N., Combaret, N., Hammas, S., Prati, F., Berry, C., Pereira, B., Lusson, J.-R., Caussin, C., Motreff, P. (2015) Invasive management without stents in selected acute coronary syndrome patients with a large thrombus burden: a prospective study of optical coherence tomography guided treatment decisions. EuroIntervention, 11, pp. 895-904. (doi: 10.4244/eijy14m07_18)

Hennigan, B., Robertson, K., Berry, C., Oldroyd, K. G. (2015) Is hyperaemia essential for accurate functional assessment of coronary stenosis severity? Interventional Cardiology Review, 10, pp. 72-78. (doi: 10.15420/icr.2015.10.2.72)

Mangion, K., Carrick, D., Payne, A. R., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2015) Left ventricular outcomes following multivessel PCI vs. infarct artery-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-P104)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Pathophysiology of myocardial remodeling in survivors of ST-elevation myocardial infarction revealed by native T1 mapping: inflammation, remote myocardium and prognostic significance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-Q52)

Robertson, K. E., Hennigan, B., Berry, C., Oldroyd, K. G. (2015) Physiological assessment of coronary lesion severity. Coronary Artery Disease, 26, pp. e8-e14. (doi: 10.1097/MCA.0000000000000212)

Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K. G., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by non-contrast T1 mapping cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O26)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by quantitative T2-weighted cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O54)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of quantitative measures of myocardial infarct pathology using native T1 mapping, in survivors of ST-elevation myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 17, pp. O53. (doi: 10.1186/1532-429X-17-S1-O53)

Kwok, C. S., Kontopantelis, E., Myint, P. K., Zaman, A., Berry, C., Keavney, B., Nolan, J., Ludman, P. F., de Belder, M. A., Buchan, I., Mamas, M. A. (2015) Stroke following percutaneous coronary intervention: type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007–12. European Heart Journal, 36, pp. 1618-1628. (doi: 10.1093/eurheartj/ehv113)

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PGR Students

Gabriela Gerganova 

  • Postgraduate Research Student 
  • Research title: Inflammatory mechanisms after ischaemic stroke

Corey McAleese

  • Postgraduate Research Student 
  • Research title: The retinal microvasculature and the systemic

Vascular remodeling is a complex process that involves physical, biochemical, and genetic components. Vascular remodelling is a process whereby a blood vessel alters its structure and this can have effects on its function. Remodelling can be brought about as an adaptive change such as a chronic rise in blood pressure, or the growth of an atherosclerotic plaque. It also occurs over a shorter time frame when a blood vessel is injured by an intervention such as stent implantation or grafting of a vein into the arterial circulation.

We have decades of experience in the field of vascular remodeling research, with expertise across a range of approaches including small vessel myography, laser scanning confocal microscopy, and autonomic control of the vasculature using electrical field stimulation to assess neurotransmitter actions in small resistance arteries. 

In addition, we employ a variety of image analysis techniques to examine vascular structure and receptor distribution.  More recently we have developed 3D techniques with laser scanning of small vessels, the creation of 3D animation, prints and Virtual Reality scenes from confocal data.

The scientific aspects of the work are directly related to normal vascular health, hypertension and vascular remodeling.  Our group has had an impact in areas of outreach and public engagement through the use of multimedia techniques for content creation.

Ongoing research topics include:

  • Vascular remodelling in the pathogenesis and development of cardiovascular and metabolic diseases.
  • Biomarker and proteomic approaches to understand fibrosis and collagen turnover.
  • The role of the enzyme AMPK and how it regulates vascular tone via action within the perivascular adipose tissue.
  • Perivascular adipose tissue (PVAT) and the control of vascular function with a particular emphasis on the effects of an enzyme known as AMPK within the PVAT and the vascular wall.
  • The effects of hypoxia on the expression and function of an enzyme known as Sphingosine Kinase (SK) and how this modulates vascular function.
  • The role of Connexins which allow communication between cells and how this affects vascular function within the pulmonary and systemic circulations.
  • The role of collagen and changes in the extracellular matrix in vascular diseases such as Ehlers Danlos Syndrome and Collagen IV related diseases.
  • Development of Machine Learning models for segmentation of vascular wall structures and VR visualisation.