Biomarkers
We measure blood-based biomarkers in observational studies and intervention studies and then use that information to understand the causes and consequences of cardiometabolic disease.
Staff
Publications
2023
McErlane, J., McCall, P., Willder, J., Berry, C., Shelley, B. (2023) Cardiac biomarkers and right ventricular dysfunction are independently associated with one year mortality in patients with COVID-19 receiving mechanical ventilation: a prospective cohort study CHEST Critical Care, 1, (doi: 10.1016/j.chstcc.2023.100015)
Cuthbert, J.J., Brown, O.I., Pellicori, P., Dobbs, K., Bulemfu, J., Kazmi, S., Sokoreli, I., Pauws, S.C., Riistama, J.M., Cleland, J.G.F., Clark, A.L. (2023) Medicines optimisation prior to discharge in patients admitted to hospital with heart failure ESC Heart Failure,
Lee, M. M. Y., Lean, M. E. J., Sattar, N., Petrie, M. C. (2023) Appetite and its regulation: are there palatable interventions for heart failure? Current Heart Failure Reports,
Mary, S., Conti-Ramsden, F., Boder, P., Parveen, H., Setjiadi, D., Fleminger, J., Brockbank, A., Graham, D., Bramham, K., Chappell, L. C., Delles, C. (2023) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension Journal of Nephrology,
Bagordo, D., Rossi, G. P., Delles, C., Wiig, H., Rossitto, G. (2023) The tangram of sodium and fluid balance: salt series Hypertension,
McDowell, K., Adamson, C., Jackson, C., Campbell, R., Welsh, P., Petrie, M. C., McMurray, J. J.V., Jhund, P., Herring, N. (2023) Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes European Journal of Heart Failure,
Ray, R., Ford, I., Cleland, J. G.F., Graham, F., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Critoph, C., Kalra, P. A., Lane, R. E., Ludman, A., Pellicori, P., Petrie, M. C., Robertson, M., Seed, A., Squire, I., Kalra, P. R. (2023) The impact of ferric derisomaltose on cardiovascular and non-cardiovascular events in patients with anemia, iron deficiency and heart failure with reduced ejection fraction Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2023.10.006)
Murphy, C. N., Delles, C., Davies, E., Connelly, P. J. (2023) Cardiovascular disease in transgender individuals Atherosclerosis, 384, (doi: 10.1016/j.atherosclerosis.2023.117282)
Sze, S., Pellicori, P., Zhang, J., Weston, J., Clark, A. L. (2023) Which frailty tool best predicts morbidity and mortality in ambulatory patients with heart failure? A prospective study European Heart Journal: Quality of Care and Clinical Outcomes, 9, pp. 731-739. (doi: 10.1093/ehjqcco/qcac073)
Welsh, P., Kimenai, D. M., Shah, A. S.V., Gadd, D. A., Marioni, R. E., Woodward, M., Sudlow, C. L.M., Campbell, A., Cleland, J. G.F., Pellicori, P., Hayward, C., Mills, N. L., Sattar, N. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study Clinical Chemistry,
Pellicori, P., Cleland, J. G.F., Borentain, M., Taubel, J., Graham, F., Khan, J., Bruzzese, D., Kessler, P., McMurray, J. J.V., Voors, A. A., O’Connor, C. M., Teerlink, J. R., Felker, G. M. (2023) Impact of vasodilators on diuretic response in patients with congestive heart failure: a mechanistic trial of cimlanod (BMS‐986231) European Journal of Heart Failure,
Cleland, J. G. F. (2023) Defining iron deficiency in patients with heart failure Nature Reviews Cardiology, (doi: 10.1038/s41569-023-00951-6)
Jackson, A. M., Macartney, M., Brooksbank, K., Brown, C., Dawson, D., Francis, M., Japp, A., Lennie, V., Leslie, S. J., Martin, T., Neary, P., Venakatasubramanian, S., Vickers, D., Weir, R. A., McMurray, J. J.V., Jhund, P. S., Petrie, M. C. (2023) A 20-year population study of peripartum cardiomyopathy European Heart Journal, (doi: 10.1093/eurheartj/ehad626)
Osmanska, J., Brooksbank, K., Docherty, K. F., Robertson, S., Wetherall, K., McConnachie, A., Hu, J., Gardner, R. S., Clark, A. L., Squire, I. B., Kalra, P. R., Jhund, P. S., Muntendam, P., McMurray, J. J.V., Petrie, M. C., Campbell, R. T. (2023) A novel, small-volume subcutaneous furosemide formulation delivered by an abdominal patch infusor device in patients with heart failure: results of two phase I studies European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvad073)
Sidik, N. P., Stanley, B., Sykes, R., Morrow, A. J., Bradley, C. P., Mcdermott, M., Ford, T., Roditi, G., Hargreaves, A., Stobo, D., Adams, J., Byrne, J., Mahrous, A., Young, R., Carrick, D., McGeoch, R., Corcoran, D., Lang, N. N., Heggie, R., Wu, O., McEntegart, M. B., McConnachie, A., Berry, C. (2023) Invasive endotyping in patients with angina and no obstructive coronary artery disease: a randomized controlled trial Circulation, (doi: 10.1161/CIRCULATIONAHA.123.064751)
Chico, T. J., Stamatakis, E., Ciravegna, F., Dunn, J., Redwood, S., Al-lamee, R., Sofat, R., Gill, J. (2023) Device-based measurement of physical activity in cardiovascular healthcare: possibilities and challenges British Journal of Sports Medicine, 57, pp. 1225-1226. (doi: 10.1136/bjsports-2022-106460)
Stamatakis, E., Ahmadi, M., Murphy, M. H., Chico, T. J., Milton, K., Del Pozo Cruz, B., Katzmarzyk, P. T., Lee, I.-M., Gill, J. (2023) Journey of a thousand miles: from ‘Manpo-Kei’ to the first steps-based physical activity recommendations British Journal of Sports Medicine, 57, pp. 1227-1228. (doi: 10.1136/bjsports-2023-106869)
Gill, J. M. R., Chico, T. J., Doherty, A., Dunn, J., Ekelund, U., Katzmarzyk, P. T., Milton, K., Murphy, M. H., Stamatakis, E. (2023) Potential impact of wearables on physical activity guidelines and interventions: Opportunities and challenges British Journal of Sports Medicine, 57, pp. 1223-1225. (doi: 10.1136/bjsports-2023-106822)
Boonpor, J., Parra-Soto, S., Talebi, A., Zhou, Z., Carrasco-Marín, F., Petermann-Rocha, F., Welsh, P., Pell, J. P., Sattar, N., Gill, J. M.R., Gray, S. R., Celis-Morales, C., Ho, F. K. (2023) Associations and predictive performance of eleven anthropometric measures with incident type 2 diabetes: a prospective cohort study from the UK Biobank Obesity, 31, pp. 2648-2657. (doi: 10.1002/oby.23849)
Ahmadi, M. N., Hamer, M., Gill, J., Murphy, M., Sanders, J. P., Doherty, A., Stamatakis, E. (2023) Brief bouts of device-measured intermittent lifestyle physical activity and its association with major adverse cardiovascular events and mortality in people who do not exercise: a prospective cohort study The Lancet Public Health, 8, pp. e800-e810. (doi: 10.1016/S2468-2667(23)00183-4)
Giommi, A., Gurgel, A. R. B., Smith, G. L., Workman, A. J. (2023) Does the small conductance Ca2+-activated K+ current ISK flow under physiological conditions in rabbit and human atrial isolated cardiomyocytes? Journal of Molecular and Cellular Cardiology, 183, pp. 70-80. (doi: 10.1016/j.yjmcc.2023.09.002)
Wei, L., Phillippo, D. M., Shah, A., Cleland, J. G.F., Lewsey, J., McAllister, D. A. (2023) Transportability of two heart failure trials to a disease registry using individual patient data Journal of Clinical Epidemiology, 162, pp. 160-168. (doi: 10.1016/j.jclinepi.2023.08.019)
Bhatt, A. S., Kosiborod, M. N., Claggett, B. L., Miao, Z. M., Vaduganathan, M., Lam, C. S. P., Hernandez, A. F., Martinez, F. A., Inzucchi, S. E., Shah, S. J., de Boer, R. A., Jhund, P. S., Desai, A. S., Fang, J. C., Han, Y., Comin‐Colet, J., Drożdż, J., Vardeny, O., Merkely, B., Lindholm, D., Peterson, M., Langkilde, A. M., McMurray, J. J. V., Solomon, S. D. (2023) Impact of COVID‐19 in patients with heart failure with mildly reduced or preserved ejection fraction enrolled in the DELIVER trial European Journal of Heart Failure, (doi: 10.1002/ejhf.3043)
Flett, A., Cebula, A., Nicholas, Z., Adam, R., Ewings, S., Prasad, S., Cleland, J. G.F., Eminton, Z., Curzen, N. (2023) Rationale and study protocol for the BRITISH randomised trial (using cardiovascular magnetic resonance identified scar as the Benchmark Risk Indication Tool for Implantable cardioverter defibrillators in patients with non-ischaemic cardiomyopathy and severe systolic heart failure) American Heart Journal, (doi: 10.1016/j.ahj.2023.09.008)
Peikert, A., Bart, B. A., Vaduganathan, M., Claggett, B. L., Kulac, I. J., Kosiborod, M. N., Desai, A. S., Jhund, P. S., Lam, C. S.P., Inzucchi, S. E., Martinez, F. A., de Boer, R. A., Hernandez, A. F., Shah, S. J., Petersson, M., Langkilde, A. M., McMurray, J. J. V., Solomon, S. D., Vardeny, O. (2023) Contemporary use and implications of beta-blockers in patients with HFmrEF or HFpEF: the DELIVER Trial JACC: Heart Failure, (doi: 10.1016/j.jchf.2023.09.007)
Logan, G., Somers, C., Baker, G., Connell, H., Gray, S., Kelly, P., McIntosh, E., Welsh, P., Gray, C., Gill, J. M. (2023) Benefits, risks, barriers, and facilitators to cycling: a narrative review Frontiers in Sports and Active Living, 5, (doi: 10.3389/fspor.2023.1168357)
Krasuska, M., Davidson, E. M., Beune, E., Jenum, A. K., Gill, J. M.R., Stronks, K., van Valkengoed, I. G.M., Diaz, E., Sheikh, A. (2023) A culturally adapted diet and physical activity text message intervention to prevent Type 2 diabetes mellitus for women of Pakistani origin living in Scotland: formative study JMIR Formative Research, 7, pp. e33810. (doi: 10.2196/33810)
Irshad, Z., Lund, J., Sillars, A., Løvsletten, N. G., Gharanei, S., Salt, I. P., Freeman, D. J., Gill, J. M.R., Thoresen, G. H., Rustan, A. C., Zammit, V. A. (2023) The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho-physiological background FASEB Journal,
Burger, P. M., Savarese, G., Tromp, J., Adamson, C., Jhund, P. S., Benson, L., Hage, C., Tay, W. T., Solomon, S. D., Packer, M., Rossello, X., McEvoy, J. W., De Bacquer, D., Timmis, A., Vardas, P., Graham, I. M., Di Angelantonio, E., Visseren, F. L.J., McMurray, J. J.V., Lam, C. S.P., Lund, L. H., Koudstaal, S., Dorresteijn, J. A.N., Mosterd, A., European Society of Cardiology’s Cardiovascular Risk Collab., (2023) Personalized lifetime prediction of survival and treatment benefit in patients with heart failure with reduced ejection fraction: the LIFE-HF model European Journal of Heart Failure,
Graham, F. J., Friday, J., Pellicori, P., Greenlaw, N., Cleland, J. G.F. (2023) Assessment of haemoglobin and serum markers of iron deficiency in people with cardiovascular disease Heart, 109, pp. 1294-1301. (doi: 10.1136/heartjnl-2022-322145)
Tromp, J., Ezekowitz, J. A., Ouwerkerk, W., Chandramouli, C., Yiu, K. H., Angermann, C. E., Dahlstrom, U., Ertl, G., Hassanein, M., Perrone, S. V., Ghadanfar, M., Schweizer, A., Obergfell, A., Dickstein, K., Collins, S. P., Filippatos, G., Cleland, J. G. F., Lam, C. S. P. (2023) Global variations according to sex in patients hospitalized for heart failure in the REPORT-HF registry JACC: Heart Failure, 11, pp. 1262-1271. (doi: 10.1016/j.jchf.2023.06.028)
Sykes, R., Doherty, D., Morrow, A., Mangion, K., Rushd, A., Berry, C. (2023) NT-proBNP in patients presenting with myocardial infarction and non-obstructive coronary arteries without left ventricular systolic dysfunction American Heart Journal Plus: Cardiology Research and Practice, 33, (doi: 10.1016/j.ahjo.2023.100311)
Bhatt, A. S., Lindholm, D., Nilsson, A., Zaozerska, N., Claggett, B. L., Vaduganathan, M., Kosiborod, M. N., Lam, C. S.P., Hernandez, A. F., Martinez, F. A., Inzucchi, S. E., Shah, S. J., de Boer, R. A., Desai, A., Jhund, P. S., Langkilde, A. M., Petersson, M., McMurray, J. J.V., Solomon, S. D. (2023) Operational challenges and mitigation measures during the COVID-19 pandemic – lessons from DELIVER American Heart Journal, 263, pp. 133-140. (doi: 10.1016/j.ahj.2023.05.013)
Morris, A., Bright, C., Cocks, M., Gibson, N., Goff, L., Greaves, C., Griffin, S., Jane, B., Kinnafick, F., Robb, P., Roberts, M., Salman, D., Saxton, J., Taylor, A., West, D., Yates, T., Andrews, R. C., Gill, J. M.R. (2023) Recommendations from Diabetes UK's 2022 diabetes and physical activity workshop Diabetic Medicine, 40, (doi: 10.1111/dme.15169)
Keast, T., McErlane, J., Kearns, R., McKinlay, S., Raju, I., Watson, M., Robertson, K. E., Berry, C., Greenlaw, N., Ackland, G., McCall, P., Shelley, B. (2023) Study protocol for IMPRoVE: a multicentre prospective observational cohort study of the incidence, impact and mechanisms of perioperative right ventricular dysfunction in non-cardiac surgery BMJ Open, 13, (doi: 10.1136/bmjopen-2023-074687)
Ranasinghe, S., Merz, C. N. B., Khan, N., Wei, J., George, M., Berry, C., Chieffo, A., Camici, P. G., Crea, F., Kaski, J. C., Marzilli, M., Gulati, M. (2023) Sex differences in Quality of Life in Patients with Ischemia with No Obstructive Coronary Artery Disease (INOCA): A Patient Self-Report Retrospective Survey from INOCA International Journal of Clinical Medicine, 12, (doi: 10.3390/jcm12175646)
Bradley, C. P., Orchard, V., McKinley, G., Heggie, R., Wu, O., Good, R., Watkins, S., Lindsay, M., Eteiba, H., McGowan, J., McGeoch, R., Corcoran, D., Kellman, P., McConnachie, A., Berry, C. (2023) The coronary microvascular angina cardiovascular magnetic resonance imaging trial: rationale and design American Heart Journal, (doi: 10.1016/j.ahj.2023.08.067)
Butt, J. H., Lu, H., Kondo, T., Bachus, E., de Boer, R. A., Inzucchi, S. E., Jhund, P. S., Kosiborod, M. N., Lam, C. S.P., Martinez, F. A., Vaduganathan, M., Solomon, S. D., McMurray, J. J.V. (2023) Heart failure, chronic obstructive pulmonary disease and efficacy and safety of dapagliflozin in HFmrEF/HFpEF: insights from DELIVER European Journal of Heart Failure, (doi: 10.1002/ejhf.3000)
Pabon, M., Claggett, B. L., Wang, X., Miao, Z. M., Chatur, S., Bhatt, A. S., Vaduganathan, M., Fang, J. C., Desai, A. S., Jhund, P., Martinez, F., De Boer, R. A., Kosiborod, M. N., Lam, C. S., Shah, S. J., Hernandez, A. F., McMurray, J. J.V., Solomon, S. D., Vardeny, O. (2023) Influence of background medical therapy on efficacy and safety of dapagliflozin in patients with heart failure with improved ejection fraction in the DELIVER trial European Journal of Heart Failure, (doi: 10.1002/ejhf.3001)
Henriksen, P. A., Hall, P., MacPherson, I. R., Joshi, S. S., Singh, T., Maclean, M., Lewis, S., Rodriguez, A., Fletcher, A., Everett, R. J., Stavert, H., Broom, A., Eddie, L., Primrose, L., McVicars, H., McKay, P., Borley, A., Rowntree, C., Lord, S., Collins, G., Radford, J., Guppy, A., Williams, M. C., Japp, A., Payne, J. R., Newby, D. E., Mills, N. L., Oikonomidou, O., Lang, N. N. (2023) A multicenter prospective randomized controlled trial of high sensitivity cardiac troponin I-guided combination angiotensin receptor blockade and beta-blocker therapy to prevent anthracycline cardiotoxicity: the Cardiac CARE trial Circulation,
Berry, C., McClure, J. D., Oldroyd, K. (2023) Death at 5-years in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a pooled analysis European Heart Journal,
Da Silva Costa, A., Ghouri, I., Johnston, A., Mcglynn, K., McNair, A., Bowman, P., Malik, N., Hurren, J., Bingelis, T., Dunne, M., Smith, G. L., Kemi, O. J. (2023) Electrically stimulated in vitro heart cell mimic of acute exercise reveals novel immediate cellular responses to exercise: reduced contractility and metabolism, but maintained calcium cycling and increased myofilament calcium sensitivity Cell Biochemistry and Function,
Brennan, A. C., Campbell, R. T., Lee, M. M.Y. (2023) Influenza vaccination: a simple, safe, and effective treatment for patients with ischaemic heart disease and heart failure European Journal of Heart Failure, (doi: 10.1002/ejhf.2993)
Chatur, S., Vaduganathan, M., Claggett, B., Vardeny, O., Desai, A. S., Jhund, P. S., de Boer, R. A., Lam, C. S.P., Kosiborod, M. N., Shah, S. J., Martinez, F., Inzucchi, S. E., Hernandez, A. F., Haddad, T., Mitter, S. S., Miao, Z. M., Petersson, M., Langkilde, A. M., McMurray, J. J.V., Solomon, S. D. (2023) Dapagliflozin and diuretic utilization in heart failure with mildly reduced or preserved ejection fraction: the DELIVER trial European Heart Journal, 44, pp. 2930-2943. (doi: 10.1093/eurheartj/ehad283)
Yeoh, S. E., Osmanska, J., Petrie, M. C., Brooksbank, K. J.M., Clark, A. L., Docherty, K. F., Foley, P. W.X., Guha, K., Halliday, C. A., Jhund, P. S., Kalra, P. R., McKinley, G., Lang, N. N., Lee, M. M.Y., McConnachie, A., McDermott, J. J., Platz, E., Sartipy, P., Seed, A., Stanley, B., Weir, R. A.P., Welsh, P., McMurray, J. J.V., Campbell, R. T. (2023) Dapagliflozin versus metolazone in heart failure resistant to loop diuretics European Heart Journal, 44, pp. 2966-2977. (doi: 10.1093/eurheartj/ehad341)
MacKenzie, S. M., Birch, L. A., Lamprou, S., Rezvanisanijouybari, P., Fayad, M., Zennaro, M.-C., Davies, E. (2023) MicroRNAs in aldosterone production and action Elsevier
AI Abel, A., Samuel, N. A., Cuthbert, J. J., Brown, O. I., Pellicori, P., Kazmi, S., Cleland, J. G.F., Johnson, M. J., Clark, A. L. (2023) Hospital admissions in the last year of life of patients with heart failure European Heart Journal: Quality of Care and Clinical Outcomes, (doi: 10.1093/ehjqcco/qcad047)
Mangion, K., Morrow, A. J., Sykes, R., Kamdar, A., Bagot, C., Bruce, G., Connelly, P., Delles, C., Gibson, V. B., Gillespie, L., Hall Barrientos, P., Lennie, V., Roditi, G., Sattar, N., Stobo, D., Allwood-Spiers, S., McConnachie, A., Berry, C., CISCO-19 investigators, (2023) Post-COVID-19 illness and associations with sex and gender BMC Cardiovascular Disorders, 23, (doi: 10.1186/s12872-023-03412-7)
Ohashi, H., Mizukami, T., Collison, D., Didagelos, M., Sakai, K., Aetesam-Ur-Rahman, M., Munhoz, D., McCartney, P., Ford, T. J., Lindsay, M., Shaukat, A., Rocchiccioli, P., Brogan, R., Watkins, S., McEntegart, M., Good, R., Robertson, K., O’Boyle, P., Davie, A., Khan, A., Hood, S., Eteiba, H., Amano, T., Sonck, J., Berry, C., De Bruyne, B., Oldroyd, K. G., Collet, C. (2023) Fractional flow reserve guided stent optimisation in focal and diffuse coronary artery disease Diagnostics, 13, (doi: 10.3390/diagnostics13152612)
Rigattieri, S., Barbato, E., Berry, C. (2023) Microvascular resistance reserve: a reference test of the coronary microcirculation? European Heart Journal, 44, pp. 2870-2872. (doi: 10.1093/eurheartj/ehad291)
Sattar, N., Taheri, S., Astling, D. P., Chadwick, J., Hinterberg, M. A., Holmes, M. V., Troth, E. V., Welsh, P. (2023) Prediction of cardiometabolic health through changes in plasma proteins with intentional weight loss in the DiRECT and DIADEM-I randomised clinical trials of type 2 diabetes remission Diabetes Care,
Jones, R. E., Gruszczyk, A. V., Schmidt, C., Hammersley, D. J., Mach, L., Lee, M., Wong, J., Yang, M., Hatipoglu, S., Lota, A. S., Barnett, S. N., Toscano-Rivalta, R., Owen, R., Raja, S., De Robertis, F., Smail, H., De-Souza, A., Stock, U., Kellman, P., Griffin, J., Dumas, M.-E., Martin, J. L., Saeb-Parsy, K., Vazir, A., Cleland, J. G.F., Pennell, D. J., Bhudia, S. K., Kalliday, B. P., Noseda, M., Frezza, C., Murphy, M. P., Prasad, S. K. (2023) Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease Nature Cardiovascular Research, 2, pp. 733-745. (doi: 10.1038/s44161-023-00312-z)
Karusheva, Y., Petry, C. J., Yasara, N., Kottahachchi, D., Premawardhena, A., Barker, P., Burling, K., Sattar, N., Welsh, P., Mettananda, S., O'Rahilly, S. (2023) Association of GDF15 levels with body mass index and endocrine status in β-thalassaemia Clinical Endocrinology, 99, pp. 182-189. (doi: 10.1111/cen.14897)
Docherty, K. F., Jackson, A. M., Macartney, M., Campbell, R. T., Petrie, M. C., Pfeffer, M. A., McMurray, J. J.V., Jhund, P. S. (2023) Declining risk of heart failure hospitalization following first acute myocardial infarction in Scotland between 1991–2016 European Journal of Heart Failure, 25, pp. 1213-1224. (doi: 10.1002/ejhf.2965)
Zhou, Z., Parra-Soto, S., Boonpor, J., Petermann-Rocha, F., Welsh, P., Mark, P. B., Sattar, N., Pell, J. P., Celis-Morales, C., Ho, F. K. (2023) Exploring the underlying mechanisms linking adiposity and cardiovascular disease: a prospective cohort study of 404,332 UK Biobank participants Current Problems in Cardiology, 48, (doi: 10.1016/j.cpcardiol.2023.101715)
Brown, C. E., Casey, H., Dominiczak, A. F., Kerr, S., Campbell, A., Delles, C. (2023) Impact of preeclampsia on cardiovascular events: an analysis of the Generation Scotland: Scottish family health study Journal of Human Hypertension, 37, pp. 735-741. (doi: 10.1038/s41371-023-00812-2)
Iaconelli, A., Pellicori, P., Caiazzo, E., Rezig, A. O. M., Bruzzese, D., Maffia, P., Cleland, J. G. F. (2023) Implanted haemodynamic telemonitoring devices to guide management of heart failure: a review and meta-analysis of randomised trials Clinical Research in Cardiology, 112, pp. 1007-1019. (doi: 10.1007/s00392-022-02104-0)
McDowell, K., Campbell, R., Simpson, J., Cunningham, J. W., Desai, A. S., Jhund, P. S., Lefkowitz, M. P., Rouleau, J. L., Swedberg, K., Zile, M. R., Solomon, S. D., Packer, M., McMurray, J. J.V. (2023) Incremental prognostic value of biomarkers in PARADIGM-HF European Journal of Heart Failure, 28, pp. 1406-1414-1406-1414. (doi: 10.1002/ejhf.2887)
Iaconelli, A., Cuthbert, J., Kazmi, S., Maffia, P., Clark, A. L., Cleland, J. G.F., Pellicori, P. (2023) Inferior vena cava diameter is associated with prognosis in patients with chronic heart failure independent of tricuspid regurgitation velocity Clinical Research in Cardiology, 112, pp. 1077-1086. (doi: 10.1007/s00392-023-02178-4)
Sykes, R., Ang, D. T. Y., Berry, C. (2023) Invasive coronary microvascular function assessment: pharmacological versus exercise testing Heart, 109, pp. 1130-1131. (doi: 10.1136/heartjnl-2023-322512)
Connelly, P. J., Delles, C. (2023) Journal of Human Hypertension special issue on sex and gender differences in hypertension Journal of Human Hypertension, 37, pp. 587-588. (doi: 10.1038/s41371-023-00847-5)
Casey, H., Dennehy, N., Fraser, A., Lees, C., McEniery, C. M., Scott, K., Wilkinson, I. B., Delles, C. (2023) Placental syndromes and maternal cardiovascular health Clinical Science, 137, pp. 1211-1224. (doi: 10.1042/CS20211130)
Olivera, S., Graham, D. (2023) Sex differences in preclinical models of hypertension Journal of Human Hypertension, 37, pp. 619-625. (doi: 10.1038/s41371-022-00770-1)
Foster, H. M.E., Gill, J. M.R., Mair, F. S., Celis-Morales, C. A., Jani, B. D., Nicholl, B. I., Lee, D., O'Donnell, C. A. (2023) Social connection and mortality in UK Biobank: a prospective cohort analysis BMC Medicine,
de Koning, M.-S. L.Y., Emmens, J. E., Romero-Hernández, E., Bourgonje, A. R., Assa, S., Figarska, S. M., Cleland, J. G.F., Samani, N. J., Ng, L. L., Lang, C. C., Metra, M., Filippatos, G. S., van Veldhuisen, D. J., Anker, S. D., Dickstein, K., Voors, A. A., Lipsic, E., van Goor, H., van der Harst, P. (2023) Systemic oxidative stress associates with disease severity and outcome in patients with new-onset or worsening heart failure Clinical Research in Cardiology, 112, pp. 1056-1066. (doi: 10.1007/s00392-023-02171-x)
Cuthbert, J.J., Cleland, J.G.F. (2023) Should we resurrect acetazolamide as a diuretic for congestion due to heart failure? Cardiovascular Research,
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Lee, M. M.Y., Kristensen, S. L., Gerstein, H. C., McMurray, J. J.V., Sattar, N. (2022) Cardiovascular and mortality outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a meta-analysis with the FREEDOM cardiovascular outcomes trial Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 16, (doi: 10.1016/j.dsx.2021.102382)
Rossing, P., Inzucchi, S. E., Vart, P., Jongs, N., Docherty, K. F., Jhund, P. S., Køber, L., Kosiborod, M. N., Martinez, F. A.,, Ponikowski, P., Sabatine, M. S., Solomon, S. D., DeMets, D. L., Bengtsson, O., Lindberg, M., Langkilde, A. M., Sjöstrand, M., Stefansson, B. V., Karlsson, C., Chertow, G. M., Hou, F. F., Correa-Rotter, R., Toto, R. D., Wheeler, D. C., McMurray, J. J.V., Heerspink, H. J.L. (2022) Dapagliflozin and new-onset type 2 diabetes in patients with chronic kidney disease or heart failure: pooled analysis of the DAPA-CKD and DAPA-HF trials Lancet Diabetes and Endocrinology, 10, pp. 24-34. (doi: 10.1016/S2213-8587(21)00295-3)
Cuthbert, J.J., Brown, O.I., Urbinati, A., Pan, D., Pellicori, P., Dobbs, K., Bulemfu, J., Kazmi, S., Sokoreli, I., Pauws, S.C., Riistama, J.M., Cleland, J.G.F., Clark, A.L. (2022) Hypochloraemia following admission to hospital with heart failure is common and associated with an increased risk of readmission or death: a report from OPERA-HF European Heart Journal: Acute Cardiovascular Care, 11, pp. 43-52. (doi: 10.1093/ehjacc/zuab097)
Delles, C. (2022) Maternally inherited essential hypertension: adding further complexity to an already complex condition American Journal of Hypertension, 35, pp. 16-18. (doi: 10.1093/ajh/hpab133)
Ferreira, J. P., Cleland, J. G., Lam, C. S.P., Anker, S. D., Mehra, M. R., van Veldhuisen, D. J., Byra, W. M., LaPolice, D. A., Greenberg, B., Zannad, F. (2022) New-onset atrial fibrillation in patients with worsening heart failure and coronary artery disease: an analysis from the COMMANDER-HF trial Clinical Research in Cardiology, 111, pp. 50-59. (doi: 10.1007/s00392-021-01891-2)
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Lam, P. H., Keramida, K., Filippatos, G. S., Gupta, N., Faselis, C., Deedwania, P., George, B., Iskandrian, A., Cleland, J. G.F., Choudhary, G., Wu, W.-C., Morgan, C. J., Fonarow, G. C., Ahmed, A. (2022) Right ventricular ejection fraction and beta-blocker effect in heart failure with reduced ejection fraction: Beta-blocker and outcomes in HFrEF by RVEF Journal of Cardiac Failure, 28, pp. 65-70. (doi: 10.1016/j.cardfail.2021.07.026)
Romaine, S. P. R., Denniff, M., Codd, V., Nath, M., Koekemoer, A., Anker, S. D., Cleland, J. G., Filippatos, G., Levin, D., Metra, M., Mordi, I. R., Ouwerkerk, W., ter Maaten, J. M., van Veldhuisen, D. J., Zannad, F., Ng, L. L., van der Harst, P., Lang, C. C., Voors, A. A., Nelson, C. P., Samani, N. J. (2022) Telomere length is independently associated with all-cause mortality in chronic heart failure Heart, 108, pp. 124-129. (doi: 10.1136/heartjnl-2020-318654)
Delles, C., Rossitto, G. (2022) Of snails, earthworms, and men: insights into strategies to preserve water Function, 3, (doi: 10.1093/function/zqab071)
Cuthbert, J. J., Pellicori, P., Clark, A. L. (2022) Optimal management of heart failure and chronic obstructive pulmonary disease: clinical challenges International Journal of General Medicine, 15, pp. 7961-7975. (doi: 10.2147/IJGM.S295467)
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Armignacco, R., Reel, P. S., Reel, S., Jouinot, A., Septier, A., Gaspar, C., Perlemoine, K., Larsen, C. K., Bouys, L., Braun, L., Riester, A., Kroiss, M., Bonnet-Serrano, F., Amar, L., Blanchard, A., Gimenez-Roqueplo, A.-P., Prejbisz, A., Januszewicz, A., Dobrowolski, P., Davies, E., MacKenzie, S. M., Rossi, G. P., Lenzini, L., Ceccato, F., Scaroni, C., Mulatero, P., Williams, T. A., Pecori, A., Monticone, S., Beuschlein, F., Reincke, M., Zennaro, M.-C., Bertherat, J., Jefferson, E., Assié, G. (2022) Whole blood methylome-derived features to discriminate endocrine hypertension Clinical Epigenetics, 14, (doi: 10.1186/s13148-022-01347-y)
2021
Andersen, E., van der Ploeg, H. P., van Mechelen, W., Gray, C. M., Mutrie, N., van Nassau, F., Jelsma, J. G. M., Anderson, A. S., Silva, M. N., Pereira, H. V., McConnachie, A., Sattar, N., Sørensen, M., Røynesdal, Ø. B., Hunt, K., Roberts, G. C., Wyke, S., Gill, J. M.R. (2021) Contributions of changes in physical activity, sedentary time, diet and body weight to changes in cardiometabolic risk International Journal of Behavioral Nutrition and Physical Activity, 18, (doi: 10.1186/s12966-021-01237-1)
Mooney, L., Hawkins, N. M., Jhund, P. S., Redfield, M. M., Muthiah Vaduganathan, M., Desai, A. S., Rouleau, J. L., Minamisawa, M., Shah, A. M., Lefkowitz, M. P., Zile, M. R., Van Veldhuisen, D. J., Pfeffer, M. A., Anand, I. S., Maggioni, A. P., Senni, M., Claggett, B. L., Solomon, S. D., McMurray, J. J. V. (2021) Impact of chronic obstructive pulmonary disease in patients with heart failure with preserved ejection fraction: insights from PARAGON‐HF Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.121.021494)
Petermann-Rocha, F., Lyall, D. M., Gray, S. R., Gill, J. M.R., Sattar, N., Welsh, P., Quinn, T. J., Stewart, W., Pell, J. P., Ho, F. K., Celis-Morales, C. (2021) Dose-response association between device-measured physical activity and incident dementia: a prospective study from UK Biobank BMC Medicine, 19, (doi: 10.1186/s12916-021-02172-5)
Connelly, P. J., Delles, C. (2021) Cardiovascular disease in transgender people: recent research and emerging evidence Cardiovascular Research, 117, pp. e174-e176. (doi: 10.1093/cvr/cvab288)
Collison, D., Didagelos, M., Aetesam-Ur-Rahman, M., Copt, S., McDade, R., McCartney, P., Ford, T. J., McClure, J., Lindsay, M., Shaukat, A., Rocchiccioli, P., Brogan, R., Watkins, S., McEntegart, M., Good, R., Robertson, K., O’Boyle, P., Davie, A., Khan, A., Hood, S., Eteiba, H., Berry, C., Oldroyd, K. G. (2021) Post-stenting fractional flow reserve vs coronary angiography for optimization of percutaneous coronary intervention (TARGET-FFR) European Heart Journal, 42, pp. 4656-4668. (doi: 10.1093/eurheartj/ehab449)
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Butt, J. H., Adamson, C., Docherty, K. F., de Boer, R. A., Petrie, M. C., Inzucchi, S. E., Kosiborod, M. N., Maria Langkilde, A., Lindholm, D., Martinez, F. A., Bengtsson, O., Schou, M., O’Meara, E., Ponikowski, P., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., Jhund, P. S., McMurray, J. J.V., Køber, L. (2021) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to N-terminal pro-B-type natriuretic peptide: insights from the DAPA-HF trial Circulation: Heart Failure, 14, (doi: 10.1161/CIRCHEARTFAILURE.121.008837)
Diamant, M. J., Andrade, J. G., Virani, S. A., Jhund, P. S., Petrie, M. C., Hawkins, N. M. (2021) Heart failure and atrial flutter: a systematic review of current knowledge and practices ESC Heart Failure, 8, pp. 4484-4496. (doi: 10.1002/ehf2.13526)
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Lang, N. N., Touyz, R. M. (2021) Mechanistic science in cardiovascular-oncology: the way forward to maximise anti-cancer drug effects and minimise cardiovascular toxicity Clinical Science, 135, pp. 2661-2663. (doi: 10.1042/CS20210986)
Desai, A. S., Vaduganathan, M., Cleland, J. G., Claggett, B. L., Barkoudah, E., Finn, P., McCausland, F. R., Yilmaz, M. B., Lefkowitz, M., Shi, V., Pfeffer, M. A., McMurray, J. J.V., Soloman, S. D. (2021) Mode of death in patients with heart failure and preserved ejection fraction: insights from PARAGON-HF Circulation: Heart Failure, 14, (doi: 10.1161/CIRCHEARTFAILURE.121.008597)
Ferreira, J. P., Girerd, N., Rocca, H.-P. B.-L., Pellicori, P., Cleland, J. G., Rossignol, P., Zannad, F. (2021) No influence of spironolactone on plasma concentrations of angiotensin-converting enzyme 2: Findings from the HOMAGE randomized trial = Pas d’influence de la spironolactone sur les concentrations plasmatiques de l’enzyme de conversion de l’angiotensine 2 : résultats de l’essai randomisé HOMAGE Archives of Cardiovascular Diseases, 114, pp. 814-817. (doi: 10.1016/j.acvd.2021.10.003)
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Wannamethee, S. G., Welsh, P., Papacosta, O., Lennon, L., Whincup, P. (2021) Vitamin D deficiency, impaired lung function and total and respiratory mortality in a cohort of older men: cross-sectional and prospective findings from the British Regional Heart Study BMJ Open, 11, (doi: 10.1136/bmjopen-2021-051560)
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Connelly, P. J., Clark, A., Touyz, R. M., Delles, C. (2021) Transgender adults, gender-affirming hormone therapy and blood pressure: a systematic review Journal of Hypertension, 39, pp. 223-230. (doi: 10.1097/HJH.0000000000002632)
Jhund, P. S., Solomon, S. D., Docherty, K. F., Heerspink, H. J.L., Anand, I. S., Böhm, M., Chopra, V., de Boer, R. A., Desai, A. S., Ge, J., Kitakaze, M., Merkely, B., O'Meara, E., Schou, M., Tereshchenko, S., Verma, S., Vinh, P. N., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Bengtsson, O., Langkilde, A. M., Sjöstrand, M., McMurray, J. J.V. (2021) Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF Circulation, 143, pp. 289-309. (doi: 10.1161/CIRCULATIONAHA.120.050391)
Samuel, N. A., Cuthbert, J. J., Brown, O. I., Kazmi, S., Cleland, J. G.F., Rigby, A. S., Clark, A. L. (2021) Relation between thyroid function and mortality in patients with chronic heart failure American Journal of Cardiology, 139, pp. 57-63. (doi: 10.1016/j.amjcard.2020.10.034)
Teerlink, J. R., Diaz, R., Felker, G. M., McMurray, J. J.V., Metra, M., Solomon, S. D., Adams, K. F., Anand, I., Arias-Mendoza, A., Biering-Sørensen, T., Böhm, M., Bonderman, D., Cleland, J. G.F., Corbalan, R., Crespo-Leiro, M. G., Dahlström, U., Echeverria, L. E., Fang, J. C., Filippatos, G., Fonseca, C., Goncalvesova, E., Goudev, A. R., Howlett, J. G., Lanfear, D. E., Li, J., Lund, M., Macdonald, P., Mareev, V., Momomura, S.-i., O’Meara, E., Parkhomenko, A., Ponikowski, P., Ramires, F. J.A., Serpytis, P., Sliwa, K., Spinar, J., Suter, T. M., Tomcsanyi, J., Vandekerckhove, H., Vinereanu, D., Voors, A. A., Yilmaz, M. B., Zannad, F., Sharpsten, L., Legg, J. C., Varin, C., Honarpour, N., Abbasi, S. A., Malik, F. I., Kurtz, C. E. (2021) Cardiac myosin activation with omecamtiv mecarbil in systolic heart failure New England Journal of Medicine, 384, pp. 105-116. (doi: 10.1056/NEJMoa2025797)
Lyall, D. M., Ward, J., Banach, M., Smith, G. D., Gill, J. G., Pell, J. P., Holmes, M. V., Sattar, N. (2021) PCSK9 genetic variants and cognitive abilities: a large-scale Mendelian randomization study Archives of Medical Science, 17, pp. 241-244. (doi: 10.5114/aoms/127226)
Corcoran, D., Radjenovic, A., Mordi, I., Nazir, S. A., Wilson, S. J., Hinder, M., Yates, D. P., Machineni, S., Alcantara, J., Prescott, M. F., Gugliotta, B., Pang, Y., Tzemos, N., Semple, S. I., Newby, D. E., McCann, G. P., Squire, I., Berry, C. (2021) Vascular effects of serelaxin in patients with stable coronary artery disease: a randomized placebo-controlled trial Cardiovascular Research, 117, pp. 320-329. (doi: 10.1093/cvr/cvz345)
Bekfani, T., Fudim, M., Cleland, J. G.F., Jorbenadze, A., Haehling, S., Lorber, A., Rothman, A. M.‐K., Stein, K., Abraham, W. T., Sievert, H., Anker, S. D. (2021) A current and future outlook on upcoming technologies in the remote monitoring of patients with heart failure European Journal of Heart Failure, 23, pp. 175-185. (doi: 10.1002/ejhf.2033)
Moreton, F. C., Cullen, B., Dickie, D. A., Lopez Gonzalez, R., Santosh, C., Delles, C., Muir, K. W. (2021) Brain imaging factors associated with progression of subcortical hyperintensities in CADASIL over two year follow up European Journal of Neurology, 28, pp. 220-228. (doi: 10.1111/ene.14534)
Dobbin, S. J.H., Petrie, M. C., Myles, R. C., Touyz, R. M., Lang, N. N. (2021) Cardiotoxic effects of angiogenesis inhibitors Clinical Science, 135, pp. 71-100. (doi: 10.1042/CS20200305)
Davison, B. A., Senger, S., Sama, I. E., Koch, G. G., Mebazaa, A., Dickstein, K., Samani, N. J., Metra, M., Anker, S. D., Cleland, J. G., Ng, L. L., Mordi, I. R., Zannad, F., Filippatos, G. S., Hillege, H. L., Ponikowski, P., Veldhuisen, D. J., Lang, C. C., Meer, P., Núñez, J., Bayés‐Genís, A., Edwards, C., Voors, A. A., Cotter, G. (2021) Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF European Journal of Heart Failure, 23, pp. 43-57. (doi: 10.1002/ejhf.2077)
He, T., Melgarejo, J. D., Clark, A. L., Yu, Y.‐L., Thijs, L., Díez, J., López, B., González, A., Cleland, J. G., Schanstra, J. P., Vlahou, A., Latosinska, A., Mischak, H., Staessen, J. A., Zhang, Z.‐Y., Jankowski, V. (2021) Serum and urinary biomarkers of collagen type‐I turnover predict prognosis in patients with heart failure Clinical and Translational Medicine, 11, (doi: 10.1002/ctm2.267)
Willder, J. M., McCall, P., Messow, C.-M., Gillies, M., Berry, C., Shelley, B. (2021) Study protocol for COVID-RV: a multicentre prospective observational cohort study of right ventricular dysfunction in ventilated patients with COVID-19 BMJ Open, 11, (doi: 10.1136/bmjopen-2020-042098)
Mortensen, P., Gao, H., Smith, G., Simitev, R. D. (2021) Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling Mathematical Medicine and Biology, 38, pp. 292-298. (doi: 10.1093/imammb/dqab005)
Jacobs, M., Benovoy, M., Chang, L.-C., Corcoran, D., Berry, C., Arai, A. E., Hsu, L.-Y. (2021) Automated segmental analysis of fully quantitative myocardial blood flow maps by first-pass perfusion cardiovascular magnetic resonance IEEE Access, 9, pp. 52796-52811. (doi: 10.1109/ACCESS.2021.3070320)
Kamdar, A., Sykes, R., Morrow, A., Mangion, K., Berry, C. (2021) Cardiovascular outcomes of glucose lowering therapy in chronic kidney disease patients: a systematic review with meta-analysis Reviews in Cardiovascular Medicine, 22, pp. 1479-1490. (doi: 10.31083/j.rcm2204152)
Da Silva Costa, A., Mortensen, P., Hortigon-Vinagre, M. P., van der Heyden, M. A. G., Burton, F. L., Gao, H., Simitev, R. D., Smith, G. L. (2021) Electrophysiology of hiPSC-cardiomyocytes co-cultured with HEK cells expressing the inward rectifier channel International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22126621)
Anderson, J. J., Welsh, P., Ho, F. K., Ferguson, L. D., Welsh, C. E., Pellicori, P., Cleland, J. G.F., Forbes, J., Iliodromiti, S., Boyle, J., Lindsay, R., Celis-Morales, C., Gray, S. R., Katikireddi, S. V., Gill, J. M. R., Pell, J. P., Sattar, N. (2021) Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening BMJ Open Diabetes Research and Care, 9, (doi: 10.1136/bmjdrc-2021-002176)
Small, H. Y., Delles, C. (2021) Letter to the Editor regarding Cunningham et al. 2020 Hypertension in Pregnancy, 40, pp. 133. (doi: 10.1080/10641955.2021.1899201)
McGettrick, M., MacLellan, A., McCaughey, P., Bagot, C., Brewis, M.J., Lang, N.N., Johnson, M.K., Church, A.C. (2021) Pulmonary thromboembolism in hospitalised patients with COVID-19: a retrospective national study of patients managed in critical care and ward environments in Scotland BMJ Open, 11, (doi: 10.1136/bmjopen-2021-050281)
Wijkman, M. O., Malachias, M. V.B., Claggett, B. L., Cheng, S., Matsushita, K., Shah, A. M., Jhund, P. S., Coresh, J., Solomon, S. D., Vardeny, O. (2021) Resistance to antihypertensive treatment and long-term risk: The Atherosclerosis Risk in Communities study Journal of Clinical Hypertension, 23, pp. 1887-1896. (doi: 10.1111/jch.14269)
Shoaib, A., Van Spall, H. G.C., Wu, J., Cleland, J. G.F., McDonagh, T. A., Rashid, M., Mohamed, M. O., Ahmed, F. Z., Deanfield, J., de Belder, M., Gale, C. P., Mamas, M. A. (2021) Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic European Heart Journal: Quality of Care and Clinical Outcomes, 7, pp. 378-387. (doi: 10.1093/ehjqcco/qcab040)
Shah, P., Pellicori, P., Hanning, I., Zhang, J., Clark, A. L., Bhandari, S. (2021) The effect of digoxin on renal function in patients with heart failure BMC Nephrology, 22, (doi: 10.1186/s12882-021-02562-0)
Sykes, R., Briscoe, M., Krystofiak, T., Peck, O., Mangion, K., Berry, C. (2021) Type 2 myocardial infarction and myocardial injury: eligibility for novel medical therapy to de-risk clinical trials Open Heart, 8, (doi: 10.1136/openhrt-2021-001633)
Ang, D. T. Y., Berry, C. (2021) What an interventionalist needs to know about INOCA Interventional Cardiology Review, 16, (doi: 10.15420/icr.2021.16)
Sykes, R., Doherty, D., Mangion, K., Morrow, A., Berry, C. (2021) What an interventionalist needs to know about MI with non-obstructive coronary arteries Interventional Cardiology Review, 16, (doi: 10.15420/icr.2021.10)
2020
Brown, R., Welsh, P., Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events Open Heart, 7, (doi: 10.1136/openhrt-2020-001396)
Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)
Lee, M. (2020) Studies of Empagliflozin and its Cardiovascular, Renal and Metabolic Effects in Patients With Diabetes Mellitus (or Prediabetes) and Heart Failure: a Randomized Controlled Trial (SUGAR-DM-HF) (doi: 10.1161/CIR.0000000000000940)
Goncalves Soares, A., Kilpi, F., Fraser, A., Nelson, S. M., Sattar, N., Welsh, P. I., Tilling, K., Lawlor, D. A. (2020) Longitudinal changes in reproductive hormones through the menopause transition in the Avon Longitudinal Study of Parents and Children (ALSPAC) Scientific Reports, 10, (doi: 10.1038/s41598-020-77871-9)
Purcell, C., Daw, P., Kerr, C., Cleland, J., Cowie, A., Dalal, H., Ibbotson, T., Murphy, C., Taylor, R. (2020) Protocol for an implementation study of an evidence-based home cardiac rehabilitation programme for people with heart failure and their caregivers in Scotland (SCOT:REACH-HF) BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040771)
Mangion, K., Morrow, A., Bagot, C., Bayes, H., Blyth, K. G., Church, C., Corcoran, D., Delles, C., Gillespie, L., Grieve, D., Ho, A., Kean, S., Lang, N. N., Lennie, V., Lowe, D., Kellman, P., Macfarlane, P. W., McConnachie, A., Roditi, G., Sykes, R., Touyz, R. M., Sattar, N., Wereski, R., Wright, S., Berry, C. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study Cardiovascular Research, 116, pp. 2185-2196. (doi: 10.1093/cvr/cvaa209)
Ferguson, A. C., Tank, R., Lyall, L. M., Ward, J., Welsh, P., Celis-Morales, C., McQueenie, R., Strawbridge, R. J., Mackay, D. F., Pell, J. P., Smith, D. J., Sattar, N., Cavanagh, J., Lyall, D. M. (2020) Association of SBP and BMI with cognitive and structural brain phenotypes in UK Biobank Journal of Hypertension, 38, pp. 2482-2489. (doi: 10.1097/HJH.0000000000002579)
Kelly, P., Williamson, C., Baker, G., Davis, A., Broadfield, S., Coles, A., Logan, G., Connell, H., Pell, J. P., Gray, C., Gill, J. M.R. (2020) Beyond cycle lanes and large-scale infrastructure: a scoping review of initiatives that groups and organisations can implement to promote cycling for the Cycle Nation Project British Journal of Sports Medicine, 54, pp. 1405-1415. (doi: 10.1136/bjsports-2019-101447)
Mangion, K., Loughrey, C., Auger, D. A., McComb, C., Lee, M. M., Corcoran, D., McEntegart, M., Davie, A., Good, R., Lindsay, M., Eteiba, H., Rocchiccioli, J. P., Watkins, S., Hood, S., Shaukat, A., Haig, C., Epstein, F. H., Berry, C. (2020) Displacement encoding with stimulated echoes enables the identification of infarct transmurality early postmyocardial infarction Journal of Magnetic Resonance Imaging, 52, pp. 1722-1731. (doi: 10.1002/jmri.27295)
Pellicori, P., Ofstad, A. P., Fitchett, D., Zeller, C., Wanner, C., George, J., Zinman, B., Brueckmann, M., Lindenfeld, J. (2020) Early benefits of empagliflozin in patients with or without heart failure: findings from EMPA-REG OUTCOME ESC Heart Failure, 7, pp. 3401-3407. (doi: 10.1002/ehf2.12891)
Felker, G. M., Solomon, S. D., McMurray, J. J.V., Cleland, J. G.F., Abbasi, S. A., Malik, F. I., Zhang, H., Globe, G., Teerlink, J. R. (2020) Effects of omecamtiv mecarbil on symptoms and health-related quality of life in patients with chronic heart failure: results from the COSMIC-HF study Circulation: Heart Failure, 13, (doi: 10.1161/CIRCHEARTFAILURE.120.007814)
Ferreira, J. P., Docherty, K. F., Stienen, S., Jhund, P. S., Claggett, B. L., Solomon, S. D., Petrie, M. C., Gregsone, J., Pocock, S. L., Zannad, F., McMurray, J. (2020) Estimating the lifetime benefits of treatments for heart failure JACC: Heart Failure, 8, pp. 984-995. (doi: 10.1016/j.jchf.2020.08.004)
Kristensen, S. L., Castagno, D., Shen, L., Jhund, P., Docherty, K., Rørth, R., Abraham, W. T., Desai, A., Dickstein, K., Rouleau, J. L., Zile, M. R., Swedberg, K., Packer, M., Solomon, S. D., Køber, L., McMurray, J. J.V. (2020) Prevalence and incidence of intra-ventricular conduction delays and outcomes in patients with heart failure and reduced ejection fraction: insights from PARADIGM‐HF and ATMOSPHERE European Journal of Heart Failure, 22, pp. 2370-2379. (doi: 10.1002/ejhf.1972)
Brown, O., Costanzo, P., Clark, A. L., Condorelli, G., Cleland, J. G.F., Sathyapalan, T., Hepburn, D., Kilpatrick, E. S., Atkin, S. L. (2020) Relationship between a single measurement at baseline of body mass index, glycated hemoglobin, and the risk of mortality and cardiovascular morbidity in type 2 diabetes mellitus Cardiovascular Endocrinology and Metabolism, 9, pp. 177-182. (doi: 10.1097/XCE.0000000000000202)
Yeoh, S. E., Dewan, P., Desai, A. S., Solomon, S. D., Rouleau, J. L., Lefkowitz, M., Rizkala, A., Swedberg, K., Zile, M. R., Jhund, P. S., Packer, M., McMurray, J. J.V. (2020) Relationship between duration of heart failure, patient characteristics, outcomes, and effect of therapy in PARADIGM-HF ESC Heart Failure, 7, pp. 3355-3364. (doi: 10.1002/ehf2.12972)
Mackenzie, I. S., Ford, I., Nuki, G., Hallas, J., Hawkey, C. J., Webster, J., Ralston, S. H., Walters, M., Robertson, M., De Caterina, R., Findlay, E., Perez-Ruiz, F., McMurray, J. J.V., MacDonald, T. M., Aziz, J., Dobson, G., Doney, A.S.F., Flynn, R.W.V., Furnace, J., Grieve, J.W.K., Guthrie, G., Jamieson, D., Jennings, C.G., Kean, S., Lund, L.C., McConnachie, A., Pigazzani, F., Riches, P.L., Rix Hanson, M., Rogers, A., Rooke, E.D.M., Thomson, J., Warren, M., Wetherall, K., Wilson, R., Hall, C.P., Maseri, A., Bird, H.A., Murray, G., Dear, J.W., Petrie, M., MacDonald, M., Jhund, P. S., Connolly, E., Murphy, D.J., Paul, N., Olsson, A., Koskinen, P.T., Fuat, A., Foster, A., Saywood, W., Barr, R.J., McConnachie, L., Wilson, L.F., Larsen Rasmussen, L., McGinnis, A.R., Birrell, H., Keiller, M., Bremner, I.S., Forbes, G.J., Dumbleton, J.S., Rhodes, J., Waller, T. (2020) Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial Lancet, 396, pp. 1745-1757. (doi: 10.1016/S0140-6736(20)32234-0)
Beazer, J. D., Patanapirunhakit, P., Gill, J. M.R., Graham, D., Karlsson, H., Ljunggren, S., Mulder, M., Freeman, D. J. (2020) High-density lipoprotein’s vascular protective functions in metabolic and cardiovascular disease - could extracellular vesicles be at play? Clinical Science, 134, pp. 2977-2986. (doi: 10.1042/CS20200892)
Ho, F. K., Celis-Morales, C. A., Gray, S. R., Katikireddi, S. V., Niedzwiedz, C. L., Hastie, C., Ferguson, L. D., Berry, C., Mackay, D. F., Gill, J. M.R., Pell, J. P., Sattar, N., Welsh, P. (2020) Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040402)
Psotka, M. A., Abraham, W. T., Fiuzat, M., Filippatos, G., Lindenfeld, J., Ahmad, T., Bhatt, A. S., Carson, P. E., Cleland, J. G.F., Felker, G. M., Januzzi, J. L., Kitzman, D. W., Leifer, E. S., Lewis, E. F., McMurray, J. J.V., Mentz, R. J., Solomon, S. D., Stockbridge, N., Teerlink, J. R., Vaduganathan, M., Vardeny, O., Whellan, D. J., Wittes, J., Anker, S. D., O'Connor, C. M. (2020) Conduct of clinical trials in the era of COVID-19: JACC scientific expert panel Journal of the American College of Cardiology, 76, pp. 2368-2378. (doi: 10.1016/j.jacc.2020.09.544)
Petermann-Rocha, F., Hanlon, P., Gray, S. R., Welsh, P., Gill, J. M.R., Foster, H., Katikireddi, S. V., Lyall, D., Mackay, D. F., O'Donnell, C., Sattar, N., Nicholl, B. I., Pell, J. P., Jani, B. D., Ho, F. K., Mair, F. S., Celis-Morales, C. (2020) Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank BMC Medicine, 18, (doi: 10.1186/s12916-020-01822-4)
Ho, F. K., Petermann-Rocha, F., Gray, S. R., Jani, B. D., Katikireddi, S. V., Niedzwiedz, C. L., Foster, H., Hastie, C. E., Mackay, D. F., Gill, J. M.R., O'Donnell, C., Welsh, P., Mair, F., Sattar, N., Celis-Morales, C. A., Pell, J. P. (2020) Is older age associated with COVID-19 mortality in the absence of other risk factors? General population cohort study of 470,034 participants PLoS ONE, 15, (doi: 10.1371/journal.pone.0241824)
Dietrichs, E. S., McGlynn, K., Allan, A., Connolly, A., Bishop, M., Burton, F., Kettlewell, S., Myles, R., Tveita, T., Smith, G. L. (2020) Moderate but not severe hypothermia causes pro-arrhythmic changes in cardiac electrophysiology Cardiovascular Research, 116, pp. 2081-2090. (doi: 10.1093/cvr/cvz309)
McEwan, P., Darlington, O., McMurray, J. J.V., Jhund, P. S., Docherty, K. F., Böhm, M., Petrie, M. C., Bergenheim, K., Qin, L. (2020) Cost-effectiveness of dapagliflozin as a treatment for heart failure with reduced ejection fraction: a multinational health-economic analysis of DAPA-HF European Journal of Heart Failure, 22, pp. 2147-2156. (doi: 10.1002/ejhf.1978)
Ferreira, J. P., Dewan, P., Jhund, P., Lorenzo-Almorós, A., Duarte, K., Petrie, M., Carson, P. E., McKelvie, R., Komajda, M., Zile, M., Zannad, F., McMurray, J. J.V. (2020) Covariate adjusted reanalysis of the I-Preserve trial Clinical Research in Cardiology, 109, pp. 1358-1365. (doi: 10.1007/s00392-020-01632-x)
Docherty, K., Jhund, P. S., Bengtsson, O., DeMets, D. L., Inzucchi, S. E., Kober, L., Kosiborod, M. N., Langkilde, A. M., Martinez, F. A., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., McMurray, J. J.V. (2020) Effect of dapagliflozin in DAPA-HF according to background glucose-lowering therapy Diabetes Care, 43, pp. 2878-2881. (doi: 10.2337/dc20-1402)
Seferović, P. M., Fragasso, G., Petrie, M., Mullens, W., Ferrari, R., Thum, T., Bauersachs, J., Anker, S. D., Ray, R., Çavuşoğlu, Y., Polovina, M., Metra, M., Ambrosio, G., Prasad, K., Seferović, J., Jhund, P. S., Dattilo, G., Čelutkiene, J., Piepoli, M., Moura, B., Chioncel, O., Ben Gal, T., Heymans, S., Jaarsma, T., Hill, L., Lopatin, Y., Lyon, A. R., Ponikowski, P., Lainščak, M., Jankowska, E., Mueller, C., Cosentino, F., Lund, L. H., Filippatos, G. S., Ruschitzka, F., Coats, A. J.S., Rosano, G. M.C. (2020) Heart Failure Association of the European Society of Cardiology update on sodium glucose co‐transporter‐2 inhibitors in heart failure (an update on the Sodium–glucose co‐transporter 2 inhibitors in heart failure: beyond glycaemic control. The position paper of the Heart Failure Association of the European Society of Cardiology) European Journal of Heart Failure, 22, pp. 1984-1986. (doi: 10.1002/ejhf.2026)
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Lyall, L. M., Wyse, C. A., Celis Morales, C. A., Lyall, D. M., Cullen, B., Mackay, D., Ward, J., Graham, N., Strawbridge, R. J., Gill, J. M.R., Ferguson, A., Bailey, M. E.S., Pell, J. P., Curtis, A. M., Smith, D. J. (2018) Seasonality of depressive symptoms in women but not in men: a cross-sectional study in the UK Biobank cohort Journal of Affective Disorders, 229, pp. 296-305. (doi: 10.1016/j.jad.2017.12.106)
Lee, M. M.Y., Petrie, M., Rocchiccioli, P., Simpson, J., Jackson, C., Brown, A., Corcoran, D., Mangion, K., Cialdella, P., Sidik, N., McEntegart, M., Shaukat, A., Rae, A., Hood, S., Peat, E., Findlay, I., Murphy, C., Cormack, A., Bukov, N., Balachandran, K., Ford, I., Wu, O., McConnachie, A., Barry, S., Berry, C. (2018) Non-Invasive Versus Invasive Management in Patients With Prior Coronary Artery Bypass Surgery With a Non-ST Segment Elevation Acute Coronary Syndrome: Comparisons Between the Randomized Controlled Pilot Trial and Registry (doi: 10.1016/S0735-1097(18)30586-2)
Malmo, V., Kelly, A., Garten, K. S., Stolen, T., Rolim, N. P. L., Wisloff, U., Smith, G., Loennechen, J. P. (2018) Aerobic interval training prevents age-dependent vulnerability to atrial fibrillation in rodents Frontiers in Physiology, 9, (doi: 10.3389/fphys.2018.00206)
Čukić, I., Shaw, R., Der, G., Chastin, S. F.M., Dontje, M. L., Gill, J. M.R., Starr, J. M., Skelton, D. A., Radaković, R., Cox, S. R., Dall, P. M., Gale, C. R., Deary, I. J. (2018) Cognitive ability does not predict objectively measured sedentary behaviour: evidence from three older cohorts Psychology and Aging, 33, pp. 288-296. (doi: 10.1037/pag0000221)
Feng, Y.-M., Thijs, L., Zhang, Z.-Y., Yang, W.-Y., Huang, Q.-F., Wei, F.-F., Kuznetsova, T., Jennings, A.-M., Delles, C., Lennox, R., Verhamme, P., Dominiczak, A., Staessen, J. A. (2018) Glomerular function in relation to circulating adhesion molecules and inflammation markers in a general population Nephrology Dialysis Transplantation, 33, pp. 426-435. (doi: 10.1093/ndt/gfx256)
Parsons, T. J., Sartini, C., Welsh, P., Sattar, N., Ash, S., Lennon, L. T., Wannamethee, S. G., Lee, I.-M., Whincup, P. H., Jefferis, B. J. (2018) Objectively measured physical activity and cardiac biomarkers: A cross sectional population based study in older men International Journal of Cardiology, 254, pp. 322-327. (doi: 10.1016/j.ijcard.2017.11.003)
Gho, J. M.I.H., Schmidt, A. F., Pasea, L., Koudstaal, S., Pujades-Rodriguez, M., Denaxas, S., Shah, A. D., Patel, R. S., Gale, C. P., Hoes, A. W., Cleland, J. G., Hemingway, H., Asselbergs, F. W. (2018) An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors BMJ Open, 8, (doi: 10.1136/bmjopen-2017-018331)
Taylor, R., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Sattar, N., Welsh, P., Peters, C., Zhyzhneuskaya, S., Hollingsworth, K. G., Al-Mrabeh, A., Rodrigues, A. M., Rehackova, L., Adamson, A. J., Sniehotta, F. F., Mathers, J. C., Ross, H. M., McIlvenna, Y., Kean, S., Ford, I., McConnachie, A., Lean, M. E.J. (2018) Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort Diabetologia, 61, pp. 589-598. (doi: 10.1007/s00125-017-4503-0)
Mogensen, U. M., Køber, L., Jhund, P. S., Desai, A. S., Senni, M., Kristensen, S. L., Dukát, A., Chen, C.-H., Ramires, F., Lefkowitz, M. P., Prescott, M. F., Shi, V. C., Rouleau, J. L., Solomon, S. D., Swedberg, K., Packer, M., McMurray, J. J.V. (2018) Sacubitril/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM-HF European Journal of Heart Failure, 20, pp. 514-522. (doi: 10.1002/ejhf.1056)
Stewart, R. A.H., Szalewska, D., Stebbins, A., Al-Khalidi, H. R., Cleland, J. G.H., Rynkiewicz, A., Drazner, M. H., White, H. D., Mark, D. B., Roy, A., Kosevic, D., Rajda, M., Jasinski, M., Leng, C. Y., Tungsubutra, W., Desvigne-Nickens, P., Velazquez, E. J., Petrie, M. C. (2018) Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy Open Heart, 5, (doi: 10.1136/openhrt-2017-000752)
Gill, J. M.R., Hawari, N. S.A., Maxwell, D. J., Louden, D., Mourselas, N., Bunn, C., Gray, C. M., van der Ploeg, H. P., Hunt, K., Martin, A., Wyke, S., Mutrie, N. (2018) Validation of a novel device to measure and provide feedback on sedentary behavior Medicine and Science in Sports and Exercise, 50, pp. 525-532. (doi: 10.1249/MSS.0000000000001458)
Chastin, S.F.M., Dontje, M.L., Skelton, D.A., Čukić, I., Shaw, R.J., Gill, J.M.R., Greig, C.A., Gale, C.R., Deary, I., Der, G., Dall, P.M. (2018) Systematic comparative validation of self-report measures of sedentary time against an objective measure of postural sitting (activPAL) International Journal of Behavioral Nutrition and Physical Activity, 15, (doi: 10.1186/s12966-018-0652-x)
ter Maaten, J. M., Voors, A. A., Damman, K., van der Meer, P., Anker, S. D., Cleland, J. G.F., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Navis, G., Ng, L., Ouwerkerk, W., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., de Borst, M. H. (2018) Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure International Journal of Cardiology, 253, pp. 84-90. (doi: 10.1016/j.ijcard.2017.10.010)
Lean, M. E.J., Leslie, W. S., Barnes, A. C., Brosnahan, N., Thom, G., McCombie, L., Peters, C., Zhyzhneuskaya, S., Al-Mrabeh, A., Hollingsworth, K. G., Rodrigues, A. M., Rehackova, L., Adamson, A. J., Sniehotta, F., Mathers, J. C., Ross, H. M., McIlvenna, Y., Stefanetti, R., Trenell, M., Welsh, P., Kean, S., Ford, I., McConnachie, A., Sattar, N., Taylor, R. (2018) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial Lancet, 391, pp. 541-551. (doi: 10.1016/S0140-6736(17)33102-1)
Conrad, N., Judge, A., Tran, J., Mohseni, H., Hedgecott, D., Crespillo, A. P., Allison, M., Hemingway, H., Cleland, J. G., McMurray, J. J.V., Rahimi, K. (2018) Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals Lancet, 391, pp. 10-16. (doi: 10.1016/S0140-6736(17)32520-5)
Sala, L., van Meer, B. J., Tertoolen, L. T., Bakkers, J., Bellin, M., Davis, R. P., Denning, C. N., Dieben, M. A., Eschenhagen, T., Giacomelli, E., Grandela, C., Hansen, A., Holman, E., Jongbloed, M. R., Kamel, S. M., Koopman, C. D., Lachaud, Q., Mannhardt, I., Mol, M. P., Mosqueira, D., Orlova, V. V., Passier, R., Ribeiro, M. C., Saleem, U., Smith, G., Burton, F. L.L., Mummery, C. L. (2018) MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo Circulation Research, 122, pp. e5-e16. (doi: 10.1161/CIRCRESAHA.117.312067)
Corcoran, D., Young, R., Cialdella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K.G., Berry, C. (2018) The effects of remote ischaemic preconditioning on coronary artery function in patients with stable coronary artery disease International Journal of Cardiology, 252, pp. 24-30. (doi: 10.1016/j.ijcard.2017.10.082)
Currie, G., Delles, C. (2018) Blood pressure targets in the elderly Journal of Hypertension, 36, pp. 234-236. (doi: 10.1097/HJH.0000000000001576)
Welsh, P. (2018) Correlating changes in metabolic status with arterial health: modest associations but any clinical implications? Hypertension, 71, pp. 227-228. (doi: 10.1161/HYPERTENSIONAHA.117.10595)
Adamson, P. D., Hunter, A., Williams, M. C., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Dweck, M. R., Mills, N. L., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D. E. (2018) Diagnostic and prognostic benefits of computed tomography coronary angiography using the 2016 National Institute for Health and Care Excellence guidance within a randomised trial Heart, 104, pp. 207-214. (doi: 10.1136/heartjnl-2017-311508)
Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Numé, A.-k., Gislason, G. H.,, Jhund, P. S., Petrie, M. C., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure European Journal of Heart Failure, 20, pp. 240-247. (doi: 10.1002/ejhf.1046)
Adamson, P. D., Hunter, A., Madsen, D. M., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Williams, M. C., Berry, C., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., Timmis, A. D., van Beek, E. J.R., Dweck, M. R., Mickley, H., Mills, N. L., Newby, D. E. (2018) High-sensitivity cardiac troponin I and the diagnosis of coronary artery disease in patients with suspected angina pectoris Circulation: Cardiovascular Quality and Outcomes, 11, (doi: 10.1161/CIRCOUTCOMES.117.004227)
Ferguson, L.D., Ntuk, U.E., Celis-Morales, C., Mackay, D.F., Pell, J.P., Gill, J.M.R., Sattar, N. (2018) Men across a range of ethnicities have a higher prevalence of diabetes: findings from a cross-sectional study of 500000 UK Biobank participants Diabetic Medicine, 35, pp. 270-276. (doi: 10.1111/dme.13551)
Cleland, J. G.F. (2018) Physicians Addicted to Prescribing Aspirin-a Disorder Of Cardiologists (PAPA-DOC) Syndrome: the headache of nonevidence-based medicine for ischemic heart disease? JACC: Heart Failure, 6, pp. 168-171. (doi: 10.1016/j.jchf.2017.11.014)
Platz, E., Jhund, P. S., Claggett, B. L., Pfeffer, M. A., Swedberg, K., Granger, C. B., Yusuf, S., Solomon, S. D., McMurray, J. J. (2018) Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality European Journal of Heart Failure, 20, pp. 295-303. (doi: 10.1002/ejhf.901)
Nikolaidou, T., Pellicori, P., Zhang, J., Kazmi, S., Goode, K. M., Cleland, J. G., Clark, A. L. (2018) Prevalence, predictors, and prognostic implications of PR interval prolongation in patients with heart failure Clinical Research in Cardiology, 107, pp. 108-119. (doi: 10.1007/s00392-017-1162-6)
Welsh, P., Kou, L., Yu, C., Anand, I., van Veldhuisen, D. J., Maggioni, A. P., Desai, A. S., Solomon, S. D., Pfeffer, M. A., Cheng, S., Gullestad, L., Aukrust, P., Ueland, T., Swedberg, K., Young, J. B., Kattan, M. W., Sattar, N., McMurray, J. J.V. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study European Journal of Heart Failure, 20, pp. 268-277. (doi: 10.1002/ejhf.988)
Emmens, J. E., Jones, D. J.L., Cao, T. H., Chan, D. C.S., Romaine, S. P.R., Quinn, P. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M., de Boer, R. A., Voors, A. A., Ng, L. L. (2018) Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure European Journal of Heart Failure, 20, pp. 260-267. (doi: 10.1002/ejhf.1101)
Anderson, J. J., Darwis, N. D.M., Mackay, D. F., Celis-Morales, C., Lyall, D. M., Sattar, N., Gill, J. M.R., Pell, J. P. (2018) Red and processed meat consumption and breast cancer: UK Biobank cohort study and meta-analysis European Journal of Cancer, 90, pp. 73-82. (doi: 10.1016/j.ejca.2017.11.022)
Ford, T. J., Corcoran, D., Berry, C. (2018) Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need Heart, 104, pp. 284-292. (doi: 10.1136/heartjnl-2017-311446)
Cotter, G., Metra, M., Davison, B. A., Jondeau, G., Cleland, J. G.F., Bourge, R. C., Milo, O., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2018) Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? European Journal of Heart Failure, 20, pp. 317-322. (doi: 10.1002/ejhf.889)
Stoumpos, S., Lees, J., Welsh, P., Hund, M., Geddes, C. C., Nelson, S. M., Mark, P. B. (2018) The utility of anti-Müllerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation Reproductive BioMedicine Online, 36, pp. 219-226. (doi: 10.1016/j.rbmo.2017.11.003)
Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C. C., van der Harst, P., Filippatos, G., Dickstein, K., Cleland, J. G., Anker, S. D., Voors, A. A. (2018) Biomarker-guided versus guideline-based treatment of patients with heart failure: results from BIOSTAT-CHF Journal of the American College of Cardiology, 71, pp. 386-398. (doi: 10.1016/j.jacc.2017.11.041)
Gale, C. R., Marioni, R. E., Čukić, I., Chastin, S. F., Dall, P. M., Dontje, M. L., Skelton, D. A., Deary, I. J., and on behalf of the Seniors USP Team, ., Coulter, E., Der, G., Dontje, M., Fitzsimons, C., Gill, J., Granat, M., Gray, C., Greig, C., Hindle, E., Laird, K., Mead, G., Mutrie, N., Palmer, V., Radakovic, R., Sattar, N., Shaw, R., Starr, J., Stewart, S. (2018) The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936 Clinical Epigenetics, 10, (doi: 10.1186/s13148-017-0438-z)
Cleland, J. G.F., Flather, M. D., Altman, D. G., Kotecha, D. (2018) Reply: an incomplete story Journal of the American College of Cardiology, 71, pp. 105. (doi: 10.1016/j.jacc.2017.10.078)
McCarroll, C. S., He, W., Foote, K., Bradley, A., Mcglynn, K., Vidler, F., Nixon, C., Nather, K., Fatta, C., Riddell, A., Bowman, P., Elliott, E. B., Bell, M., Hawksby, C., MacKenzie, S. M., Morrison, L. J., Terry, A., Blyth, K., Smith, G. L., McBride, M. W., Kubin, T., Braun, T., Nicklin, S. A., Cameron, E. R., Loughrey, C. M. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)
Cleland, J. G.F., Bunting, K. V., Flather, M. D., Altman, D. G., Holmes, J., Coats, A. J.S., Manzano, L., McMurray, J. J.V., Ruschitzka, F., van Veldhuisen, D. J., von Lueder, T. G., Böhm, M., Andersson, B., Kjekshus, J., Packer, M., Rigby, A. S., Rosano, G., Wedel, H., Hjalmarson, Å., Wikstrand, J., Kotecha, D. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials European Heart Journal, 39, pp. 26-35. (doi: 10.1093/eurheartj/ehx564)
Kristensen, S. L., Mogensen, U. M., Tarnesby, G., Gimpelewicz, C. R., Ali, M. A., Shao, Q., Chiang, Y., Jhund, P. S., Abraham, W. T., Dickstein, K., McMurray, J. J.V., Køber, L. (2018) Aliskiren alone or in combination with enalapril vs. enalapril among patients with chronic heart failure with and without diabetes: a subgroup analysis from the ATMOSPHERE trial European Journal of Heart Failure, 20, pp. 136-147. (doi: 10.1002/ejhf.896)
Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)
Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P., Pasupathy, D., Seed, P., Koletzko, B., Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition Journal of Clinical Endocrinology and Metabolism, 103, pp. 346-355. (doi: 10.1210/jc.2017-00876)
Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)
Beggs, S. A.S., Jhund, P. S., Jackson, C. E., McMurray, J. J.V., Gardner, R. S. (2018) Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis Heart, 104, pp. 144-150. (doi: 10.1136/heartjnl-2016-310850)
Muilwijk, M., Celis-Morales, C., Nicolaou, M., Snijder, M. B., Gill, J. M.R., van Valkengoed, I. G.M. (2018) Plasma cholesteryl ester fatty acids do not mediate the association of ethnicity with type 2 diabetes: results from the HELIUS study Molecular Nutrition and Food Research, 62, (doi: 10.1002/mnfr.201700528)
Maznyczka, A. M., McCartney, P., Berry, C. (2018) Reference invasive tests of microvascular injury in myocardial infarction BMJ Open, 104, pp. 90-92. (doi: 10.1136/heartjnl-2017-311695)
Lee, M. M.Y., Petrie, M. C., Rocchiccioli, P., Simpson, J., Jackson, C., Brown, A., Corcoran, D., Mangion, K., Cialdella, P., Sidik, N., McEntegart, M., Shaukat, A., Rae, A., Hood, S., Peat, E., Findlay, I., Murphy, C., Cormack, A., Bukov, N., Balachandran, K., Ford, I., Wu, O., McConnachie, A., Barry, S., Berry, C. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial (doi: 10.1136/heartjnl-2018-BCIS.9)
Souteyrand, G., Valladier, M., Amabile, N., Derimay, F., Harbaoui, B., Leddet, P., Barnay, P., Malcles, G., Mulliez, A., Berry, C., Eschalier, R., Combaret, N., Motreff, P. (2018) Diagnosis and management of spontaneously recanalized coronary thrombus guided by optical coherence tomography ― lessons from the French “Lotus Root” registry ― Circulation Journal, 82, pp. 783-790. (doi: 10.1253/circj.cj-17-0810)
Lachaud, Q., MacQuaide, N., Burton, F., Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model Biophysical Journal, 114, pp. 625A. (doi: 10.1016/j.bpj.2017.11.3377)
Berry, C., Carberry, J., Mangion, K. (2018) How to mend a broken heart? JACC: Cardiovascular Imaging, 11, pp. 420-422. (doi: 10.1016/j.jcmg.2017.02.017)
McAllister, D. A., Read, S., Kerssens, J., Livingstone, S., McGurnaghan, S., Jhund, P., Petrie, J., Sattar, N., Fischbacher, C., Kristensen, S. L., McMurray, J., Colhoun, H. M., Wild, S. (2018) Incidence of hospitalisation for heart failure and case-fatality among 3.25 million people with and without diabetes Circulation, 138, pp. 2774-2785. (doi: 10.1161/CIRCULATIONAHA.118.034986)
Rørth, R., Fosbøl, E. L., Kragholm, K., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795)
Layland, J., Tong, D., Lee, M., Berry, C. (2018) ST and T-Wave Abnormality as Footprint of Myocardial Oedema in Non–ST-Elevation Myocardial Infarction (doi: 10.1016/j.hlc.2018.06.515)
Delles, C., Carrick, E., Graham, D., Nicklin, S. A. (2018) Utilising proteomics to understand and define hypertension: where are we and where do we go? Expert Review of Proteomics, 15, pp. 581-592. (doi: 10.1080/14789450.2018.1493927)
2017
Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C., Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)
Van't Veer, M., Pijls, N. H.J., Hennigan, B., Watkins, S., Ali, Z. A., De Bruyne, B., Zimmermann, F. M., van Nunen, L. X., Barbato, E., Berry, C., Oldroyd, K. G. (2017) Comparison of different diastolic resting indexes to iFR: are they all equal? Journal of the American College of Cardiology, 70, pp. 3088-3096. (doi: 10.1016/j.jacc.2017.10.066)
Ford, T. J., Berry, C., De Bruyne, B., Yong, A. C.S., Barlis, P., Fearon, W. F., Ng, M. K.C. (2017) Physiological predictors of acute coronary syndromes: emerging insights from the plaque to the vulnerable patient JACC: Cardiovascular Interventions, 10, pp. 2539-2547. (doi: 10.1016/j.jcin.2017.08.059)
Berry, C., McClure, J. D., Oldroyd, K. G. (2017) Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution Circulation, 136, pp. 2389-2391. (doi: 10.1161/CIRCULATIONAHA.117.030430)
Lei, C. L., Wang, K., Clerx, M., Johnstone, R. H., Hortigon-Vinagre, M. P., Zamora, V., Allan, A., Smith, G. L., Gavaghan, D. J., Mirams, G. R., Polonchuk, L. (2017) Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00986)
Dybus, A., Paul, L., Wyke, S., Brewster, S., Gill, J. M.R., Ramsay, A., Campbell, E. (2017) Validation of smartphone step count algorithm used in STARFISH smartphone application Technology and Health Care, 25, pp. 1157-1162. (doi: 10.3233/thc-170970)
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Gu, Y.-M., Thijs, L., Liu, Y.-P., Zhang, Z., Jacobs, L., Koeck, T., Zurbig, P., Lichtinghagen, R., Brand, K., Kuznetsova, T., Olivi, L., Verhamme, P., Delles, C., Mischak, H., Staessen, J. A. (2014) The urinary proteome as correlate and predictor of renal function in a population study Nephrology Dialysis Transplantation, 29, pp. 2260-2268. (doi: 10.1093/ndt/gfu234)
Sattar, N., Gill, J. (2014) Type 2 diabetes as a disease of ectopic fat? BMC Medicine, 12, (doi: 10.1186/s12916-014-0123-4)
Padmanabhan, S., Graham, L., Ferreri, N. R., Graham, D., McBride, M., Dominiczak, A. (2014) Uromodulin, an emerging novel pathway for blood pressure regulation and hypertension Hypertension, 64, pp. 918-923. (doi: 10.1161/HYPERTENSIONAHA.114.03132)
2013
Hoydal, M.A., Kaurstad, G., Rolim, N.P., Johnsen, A.B., Alves, M., Koch, L.G., Britton, S.L., Stolen, T.O., Smith, G.L., Wisloff, U. (2013) High inborn aerobic capacity does not protect the heart following myocardial infarction Journal of Applied Physiology, 115, pp. 1788-1795. (doi: 10.1152/japplphysiol.00312.2013)
Wong, C.M., Hawkins, N.M., Jhund, P.S., MacDonald, M., Solomon, S.D., Granger, C.B., Yusuf, S., Pfeffer, M.A., Swedberg, K., Petrie, M.C., McMurray, J.J.V. (2013) Clinical characteristics and outcomes of young and very young adults with heart failure: the CHARM programme Journal of the American College of Cardiology, 62, pp. 1845-1854. (doi: 10.1016/j.jacc.2013.05.072)
Layland, J., Curzen, N., Sood, A., Das, R., Balachandran, K., Junejo, S., Lee, M. M., Ahmed, N., Abouzaid, A. M., Petrie, M. C., Eteiba, H., Watkins, S., Lindsay, M. M., McEntegart, M. B., Davie, A., Henderson, R. A., Ford, I., Oldroyd, K. G., Berry, C. (2013) TCT-82 Fractional Flow Reserve versus Angiography in Guiding Management to Optimize Outcomes in Non-ST Elevation Myocardial Infarction (FAMOUS - NSTEMI) Clinical Trial: Relationships Between FFR and Angiographic Stenosis Severity at Baseline. Journal of the American College of Cardiology, 62, pp. B26. (doi: 10.1016/j.jacc.2013.08.817)
Layland, J., Sood, A., Curzen, N., Balachandran, K., Das, R., Junejo, S., Lee, M. M., Ahmed, N., Abouzaid, A. M., Beck, A., Eteiba, H., Petrie, M. C., Lindsay, M. M., Hood, S., Watkins, S., McEntegart, M. B., Owens, C., Davie, A., Peat, E., Henderson, R. A., Briggs, A., Ford, I., Oldroyd, K. G., Berry, C. (2013) TCT-84 Fractional Flow Reserve versus Angiography in Guiding Management to Optimize Outcomes in Non-ST Elevation Myocardial Infarction (FAMOUS - NSTEMI) Clinical Trial: Study Design and Baseline Characteristics of Randomized Participants. Journal of the American College of Cardiology, 62, pp. B27. (doi: 10.1016/j.jacc.2013.08.1636)
McGeoch, R.J., Payne, A.R., Woodward, R., Saul, A., Steedman, T., Foster, J., Hood, S., Peat, E., Lindsay, M.M., Petrie, M.C., Rae, A.P., McEntegart, M., Eteiba, H., Tzemos, N., Oldroyd, K.G., Berry, C. (2013) Diagnostic utility of cardiac magnetic resonance imaging in STEMI survivors after emergency PCI International Journal of Cardiology, 168, pp. 2933-2934. (doi: 10.1016/j.ijcard.2013.03.179)
Berry, C., Layland, J., Sood, A., Curzen, N. P., Balachandran, K. P., Das, R., Junejo, S., Henderson, R. A., Briggs, A. H., Ford, I., Oldroyd, K. G. (2013) Fractional flow reserve versus angiography in guiding management to optimize outcomes in non–ST-elevation myocardial infarction (FAMOUS-NSTEMI): rationale and design of a randomized controlled clinical trial American Heart Journal, 166, pp. 662-668.e3. (doi: 10.1016/j.ahj.2013.07.011)
Brown, C.E., Hastie, C.E., Alghamdi, J., Schulz, C., Hocking, L.J., Luciano, M., Porteous, D., Morris, A., Smith, B.H., Dominiczak, A.F., Tobias, E.S., Delles, C., Padmanabhan, S. (2013) Predictors of QTc and QTc prolongation in the generation scotland family study Journal of Human Hypertension, 27, pp. 639. (doi: 10.1038/jhh.2013.72)
Ghouri, N., Purves, D., McConnachie, A., Wilson, J., Gill, J.M.R., Sattar, N. (2013) Lower cardiorespiratory fitness contributes to increased insulin resistance and fasting glycaemia in middle-aged South Asian compared with European men living in the UK Diabetologia, 56, pp. 2238-2249. (doi: 10.1007/s00125-013-2969-y)
Feinkohl, I., Keller, M., Robertson, C. M., Morling, J. R., Williamson, R. M., Nee, L. D., McLachlan, S., Sattar, N., Welsh, P., Reynolds, R. M., Russ, T. C., Deary, I. J., Strachan, M. W.J., Price, J. F. (2013) Clinical and subclinical macrovascular disease as predictors of cognitive decline in older patients with type 2 diabetes: the Edinburgh type 2 diabetes study Diabetes Care, 36, pp. 2779-2786. (doi: 10.2337/dc12-2241)
Robertson, S., MacKenzie, S. M., Alvarez-Madrazo, S., Diver, L. A., Lin, J., Stewart, P. M., Fraser, R., Connell, J. M., Davies, E. (2013) MicroRNA-24 is a novel regulator of aldosterone and cortisol production in the human adrenal cortex Hypertension, 62, pp. 572-578. (doi: 10.1161/HYPERTENSIONAHA.113.01102)
Tsang, H., Leiper, J., Lao, K. H., Dowsett, L., Delahaye, M. W., Barnes, G., Wharton, J., Howard, L., Iannone, L., Lang, N. N., Wilkins, M. R., Wojciak-Stothard, B. (2013) Role of asymmetric methylarginine and connexin 43 in the regulation of pulmonary endothelial function Pulmonary Circulation, 3, pp. 675-691. (doi: 10.1086/674440)
Hotchkiss, J.W., Dundas, R., Davies, C., Hawkins, N.M., Jhund, P.S., Scholes, S., Bajekal, M., O'Flaherty, M., Critchley, J.A., Leyland, A., Capewell, S. (2013) OP53 explaining Scottish coronary heart disease mortality trends between 2000 and 2010: socioeconomic analyses using the impact sec model Journal of Epidemiology and Community Health, 67, pp. A26-A26. (doi: 10.1136/jech-2013-203126.53)
Wald, D.S., Morris, J.K., Wald, N.J., Chase, A., Edwards, R., Hughes, L., Berry, C., Oldroyd, K.G. (2013) Randomised trial of preventive angioplasty in myocardial infarction New England Journal of Medicine, 369, pp. 1115-1123. (doi: 10.1056/NEJMoa1305520)
Montezano, A. C., Yusuf, H., Graham, D., Touyz, R. M. (2013) Redox-sensitive osteogenic factors as novel mediators of vascular injury in hypertension Hypertension, 62, pp. A490.
Sever, P.S., Poulter, N.R., Chang, C.L., Thom, S.A.M., Hughes, A.D., Welsh, P., Sattar, N. (2013) Evaluation of C-reactive protein before and on-treatment as a predictor of benefit of atorvastatin Journal of the American College of Cardiology, 62, pp. 717-729. (doi: 10.1016/j.jacc.2013.02.098)
Rossi, S. H., McQuarrie, E. P., Miller, W. H., MacKenzie, R. M., Dymott, J. A., Moreno, M. U., Taurino, C., Miller, A. M., Neisius, U., Berg, G. A., Valuckiene, Z., Hannay, J. A., Dominiczak, A. F., Delles, C. (2013) Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease BMC Nephrology, 14, (doi: 10.1186/1471-2369-14-173)
McMurray, J. J.V., Jhund, P. S. (2013) Cardiovascular risks with azithromycin New England Journal of Medicine, 369, pp. 579-580. (doi: 10.1056/NEJMc1306999)
Ord, E. N.J., Shirley, R., McClure, J. D., McCabe, C., Kremer, E. J., Macrae, I. M., Work, L. M. (2013) Combined antiapoptotic and antioxidant approach to acute neuroprotection for stroke in hypertensive rats Journal of Cerebral Blood Flow and Metabolism, 33, pp. 1215-1224. (doi: 10.1038/jcbfm.2013.70)
Carrick, D., McEntegart, M., Haig, C., Petrie, M.C., Eteiba, H., Hood, S., Owens, C., Watkins, S., Layland, J., Behan, M., Sood, A., Hillis, W.S., Mordi, I., Ahmed, N., Genereux, P., Ford, I., Berry, C. (2013) A randomised controlled trial of deferred stenting versus immediate stenting to prevent no-reflow in acute ST-elevation myocardial infarction Scottish Medical Journal, 58, pp. e41-e41. (doi: 10.1177/0036933013495794)
Brown, C., Murday, V., Oxnard, D., Anusas, J., Tobias, E.S., Delles, C., Findlay, I. (2013) Sudden death referrals to the West of Scotland Inherited Cardiac Conditions Clinic: an overview of findings in probands with a structurally normal heart Scottish Medical Journal, 58, pp. e40-e41. (doi: 10.1177/0036933013495794)
Kettlewell, S., Burton, F. L., Smith, G. L., Workman, A. J. (2013) Chronic myocardial infarction promotes atrial action potential alternans, afterdepolarisations and fibrillation Cardiovascular Research, 99, pp. 215-224. (doi: 10.1093/cvr/cvt087)
Venkatasubramanian, S., Noh, R. M., Daga, S., Langrish, J. P., Joshi, N. V., Mills, N. L., Hoffmann, E., Jacobson, E. W., Vlasuk, G. P., Waterhouse, B. R., Lang, N. N., Newby, D. E. (2013) Cardiovascular effects of a novel SIRT1 activator, SRT2104, in otherwise healthy cigarette smokers Journal of the American Heart Association, 2, (doi: 10.1161/JAHA.113.000042)
McDonald, R. A., White, K. M., Wu, J., Cooley, B. C., Robertson, K. E., Halliday, C. A., McClure, J. D., Francis, S., Lu, R., Kennedy, S., George, S. J., Wan, S., van Rooij, E., Baker, A. H. (2013) miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation European Heart Journal, 34, pp. 1636-1643. (doi: 10.1093/eurheartj/eht105)
Farah, N.M.F., Gill, J.M.R. (2013) Effects of exercise before or after meal ingestion on fat balance and postprandial metabolism in overweight men British Journal of Nutrition, 109, pp. 2297-2307. (doi: 10.1017/S0007114512004448)
Carty, D.M., Dominiczak, A., Delles, C. (2013) Pulse wave analysis for prediction of preeclampsia Endocrine Reviews, 34, pp. SAT-520.
Berry, C., Lloyd, S.M., Wang, Y., MacDonald, A., Ford, I. (2013) The changing course of aortic valve disease in Scotland: temporal trends in hospitalizations and mortality and prognostic importance of aortic stenosis European Heart Journal, 34, pp. 1538-1547. (doi: 10.1093/eurheartj/ehs339)
Al Suhaim, S.A., Lewsey, J.L., Jhund, P.S., McMurray, J.J.V. (2013) 129 prescribing multiple classes of evidence based pharmacotherapy in the community is associated with lower mortality Heart, 99, (doi: 10.1136/heartjnl-2013-304019.129)
Delles, C., Freel, E.M. (2013) Aldosterone, vascular endothelial growth factor, and preeclampsia: a mystery solved? Hypertension, 61, pp. 958-960. (doi: 10.1161/HYPERTENSIONAHA.111.00767)
Delles, C. (2013) Homocysteine and the very elderly Journal of Hypertension, 31, pp. 874-876. (doi: 10.1097/HJH.0b013e328360aa8b)
Campbell, R. T., McMurray, J. J.V. (2013) Reply: Diagnosis of Heart Failure With Preserved Ejection Fraction: Still a Challenge, Journal of the American College of Cardiology, Volume 61, Issue 16, 23 April 2013, Pages 1748-1749 Journal of the American College of Cardiology, 61, pp. 1749. (doi: 10.1016/j.jacc.2013.01.012)
Carrick, D., Berry, C. (2013) Prognostic importance of myocardial infarct characteristics European Heart Journal: Cardiovascular Imaging, 14, pp. 313-315. (doi: 10.1093/ehjci/jes296)
Berry, C., van 't Veer, M., Witt, N., Kala, P., Bocek, O., Pyxaras, S.A., McClure, J.D., Fearon, W.F., Barbato, E., Tonino, P.A.L., De Bruyne, B., Pijls, N.H.J., Oldroyd, K.G. (2013) VERIFY (VERification of Instantaneous Wave-Free Ratio and Fractional Flow Reserve for the Assessment of Coronary Artery Stenosis Severity in EverydaY Practice): A Multicenter Study in Consecutive Patients Journal of the American College of Cardiology, 61, pp. 1421-1427. (doi: 10.1016/j.jacc.2012.09.065)
McComb, C., Berry, C. (2013) Prognostic importance of a new measure of global systolic heart function in healthy adults Hypertension, 61, pp. 762-764. (doi: 10.1161/HYPERTENSIONAHA.112.199992)
Ahmed, N., Carrick, D., Layland, J., Oldroyd, K. G., Berry, C. (2013) The role of cardiac magnetic resonance imaging (MRI) in acute myocardial infarction (AMI) Heart, Lung and Circulation, 22, pp. 243-255. (doi: 10.1016/j.hlc.2012.11.016)
Baker, A. H., Delles, C. (2013) Is microRNA-376c a biomarker or mediator of preeclampsia? Hypertension, 61, pp. 767-769. (doi: 10.1161/HYPERTENSIONAHA.111.00087)
Perez, A.C., Jhund, P., Preiss, D., Kjekshus, J., McMurray, J.J.V. (2013) Effect of rosuvastatin on fatigue in patients with heart failure Journal of the American College of Cardiology, 61, pp. 1121-1122. (doi: 10.1016/j.jacc.2012.12.004)
Gao, H., Kadir, K., Payne, A. R., Soraghan, J., Berry, C. (2013) Highly automatic quantification of myocardial oedema in patients with acute myocardial infarction using bright blood T2-weighted CMR Journal of Cardiovascular Magnetic Resonance, 15, (doi: 10.1186/1532-429X-15-28)
MacKenzie, R.M., Salt, I.P., Miller, W.H., Logan, A., Ibrahim, H.A., Degasperi, A., Dymott, J.A., Hamilton, C.A., Murphy, M.P., Delles, C., Dominiczak, A.F. (2013) Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes Clinical Science, 124, pp. 403-411. (doi: 10.1042/CS20120239)
Lu, X., Ginsburg, K.S., Kettlewell, S., Bossuyt, J., Smith, G.L., Bers, D.M. (2013) Measuring local gradients of intramitochondrial [Ca2+] in cardiac myocytes during sarcoplasmic reticulum Ca2+ release Circulation Research, 112, pp. 424-431. (doi: 10.1161/CIRCRESAHA.111.300501)
Bryce, G.J., Payne, D.J., Gibson, S.C., Byrne, D.S., Delles, C., McClure, J.D., Kingsmore, D. (2013) B-type natriuretic peptide predicts postoperative cardiac events and mortality after elective open abdominal aortic aneurysm repair Journal of Vascular Surgery, 57, pp. 345-353. (doi: 10.1016/j.jvs.2012.07.053)
Whyte, L.J., Ferguson, C., Wilson, J., Scott, R.A., Gill, J.M.R. (2013) Effects of single bout of very high-intensity exercise on metabolic health biomarkers in overweight/obese sedentary men Metabolism, 62, pp. 212-219. (doi: 10.1016/j.metabol.2012.07.019)
Tillin, T., Hughes, A.D., Godsland, I.F., Whincup, P., Forouhi, N.G., Welsh, P., Sattar, N., McKeigue, P.M., Chaturvedi, N. (2013) Insulin resistance and truncal obesity as important determinants of the greater incidence of diabetes in Indian Asians and African Caribbeans compared with Europeans: the Southall and Brent REvisited (SABRE) cohort Diabetes Care, 36, pp. 383-393. (doi: 10.2337/dc12-0544)
Fearon, W. F., Low, A. F., Yong, A. S., McGeoch, R., Berry, C., Shah, M. G., Ho, M. Y., Kim, H.-S., Loh, J. P., Oldroyd, K. G. (2013) Prognostic value of the index of microcirculatory resistance measured after primary percutaneous coronary intervention Circulation, 127, pp. 2436-2441. (doi: 10.1161/CIRCULATIONAHA.112.000298)
Guo, Y., Lanktree, M. B., Taylor, K. C., Hakonarson, H., Lange, L. A., Keating, B. J., Padmanabhan, S., Delles, C., Dominiczak, A. F., Hastie, C. (2013) Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals Human Molecular Genetics, 22, pp. 184-201. (doi: 10.1093/hmg/dds396)
Carrick, D., Behan, M., Foo, F., Christie, J., Hillis, W. S., Norrie, J., Oldroyd, K. G., Berry, C. (2013) Usefulness of fractional flow reserve to improve diagnostic efficiency in patients with non-ST elevation myocardial infarction American Journal of Cardiology, 111, pp. 45-50. (doi: 10.1016/j.amjcard.2012.08.046)
Alvarez-Madrazo, S., MacKenzie, S.M., Davies, E., Fraser, R., Lee, W.K., Brown, M., Caulfield, M.J., Dominiczak, A.F., Farrall, M., Lathrop, M., Hedner, T., Melander, O., Munroe, P.B., Samani, N., Stewart, P.M., Wahlstrand, B., Webster, J., Palmer, C.N.A., Padmanabhan, S., Connell, J.M. (2013) Common polymorphisms in the CYP11B1 and CYP11B2 genes: evidence for a digenic influence on hypertension Hypertension, 61, pp. 232-239. (doi: 10.1161/HYPERTENSIONAHA.112.200741)
Japp, A. G., Chelliah, R., Tattersall, L., Lang, N. N., Meng, X., Weisel, K., Katz, A., Burt, D., Fox, K. A.A., Feuerstein, G. Z., Connolly, T. M., Newby, D. E. (2013) Effect of PSI-697, a novel P-selectin inhibitor, on platelet-monocyte aggregate formation in humans Journal of the American Heart Association, 2, (doi: 10.1161/JAHA.112.006007)
Kulkarni, M. J., Korwar, A. M., Mary, S., Bhonsle, H. S., Giri, A. P. (2013) Glycated proteome: from reaction to intervention Proteomics Clinical Applications, 7, pp. 155-170. (doi: 10.1002/prca.201200101)
Di Diego, J.M., Sicouri, S., Myles, R.C., Burton, F., Smith, G.L., Antzelevitch, C. (2013) Optical and electrical recordings from isolated coronary-perfused ventricular wedge preparations Journal of Molecular and Cellular Cardiology, 54, pp. 53-64. (doi: 10.1016/j.yjmcc.2012.10.017)
Wang, H.M., Gao, H., Luo, X.Y., Berry, C., Griffith, B.E., Ogden, R.W., Wang, T.J. (2013) Structure-based finite strain modelling of the human left ventricle in diastole International Journal for Numerical Methods in Biomedical Engineering, 29, pp. 83-103. (doi: 10.1002/cnm.2497)
Zhu, Y., Luo, X., Wang, H., Ogden, R., Berry, C. (2013) Three-dimensional non-linear buckling of thick-walled elastic tubes under pressure International Journal of Non-Linear Mechanics, 48, pp. 1-14. (doi: 10.1016/j.ijnonlinmec.2012.06.013)
Murphy, A., Fenwick, E., Toff, W.D., Neilson, M.P., Berry, C., Uren, N., Oldroyd, K.G., Briggs, A.H. (2013) Transcatheter aortic valve implantation for severe aortic stenosis: the cost-effectiveness case for inoperable patients in the United Kingdom International Journal of Technology Assessment in Health Care, 29, pp. 12-19. (doi: 10.1017/S0266462312000670)
Venkatasubramanian, S., Griffiths, M. E., McLean, S. G., Miller, M. R., Luo, R., Lang, N. N., Newby, D. E. (2013) Vascular effects of Urocortins 2 and 3 in healthy volunteers Journal of the American Heart Association, 2,
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Husi, H., Sanchez-Niño, M., Delles, C., Mullen, W., Vlahou, A., Ortiz, A., Mischak, H. (2013) A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI BMC Systems Biology, 7, (doi: 10.1186/1752-0509-7-110)
Brittain, J.F., McCabe, C., Khatun, H., Kaushal, N., Bridges, L.R., Holmes, W.M., Barrick, T.R., Graham, D., Dominiczak, A.F., Macrae, I. M., Hainsworth, A.H. (2013) An MRI-histological study of white matter in stroke-free SHRSP Journal of Cerebral Blood Flow and Metabolism, 33, pp. 760-763. (doi: 10.1038/jcbfm.2013.14)
Cleland, J. G., Abraham, W. T., Linde, C., Gold, M. R., Young, J. B., Daubert, J. C., Sherfesee, L., Wells, G. A., Tang, A. S.L. (2013) An individual patient meta-analysis of five randomized trials assessing the effects of cardiac resynchronization therapy on morbidity and mortality in patients with symptomatic heart failure European Heart Journal, 34, pp. 3547-3556. (doi: 10.1093/eurheartj/eht290)
Inglis, S.C., Lewsey, J.D., Lowe, G.D.O., Jhund, P., Gillies, M., Stewart, S., Capewell, S., MacIntyre, K., McMurray, J.J.V. (2013) Angina and intermittent claudication in 7403 participants of the 2003 Scottish Health Survey: impact on general and mental health, quality of life and five-year mortality International Journal of Cardiology, 167, pp. 2149-2155. (doi: 10.1016/j.ijcard.2012.05.099)
White, K. M., Alba, R., Parker, A. L., Wright, A. F., Bradshaw, A. C., Delles, C., McDonald, R. A., Baker, A. H. (2013) Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile Journal of Cardiothoracic Surgery, 8, (doi: 10.1186/1749-8090-8-183)
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Douglas, A., Bhopal, R.S., Bhopal, R., Forbes, J.F., Gill, J.M.R., McKnight, J., Murray, G., Sattar, N., Sharma, A., Wallia, S., Wild, S., Sheikh, A. (2013) Design and baseline characteristics of the PODOSA (prevention of diabetes and obesity in South Asians) trial: a cluster, randomised lifestyle intervention in Indian and Pakistani adults with impaired glycaemia at high risk of developing type 2 diabetes BMJ Open, 3, pp. e002226-e002226. (doi: 10.1136/bmjopen-2012-002226)
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Tarr, D., Graham, D., Roy, L.A., Holmes, W.M., McCabe, C., Macrae, I.M., Muir, K.W., Dewar, D. (2013) Hyperglycemia accelerates apparent diffusion coefficient-defined lesion growth after focal cerebral ischemia in rats with and without features of metabolic syndrome Journal of Cerebral Blood Flow and Metabolism, 33, pp. 1556-1563. (doi: 10.1038/jcbfm.2013.107)
Gao, H., Griffith, B. E., Carrick, D., McComb, C., Berry, C., Luo, X. (2013) Initial experience with a dynamic imaging-derived immersed boundary model of human left ventricle Springer Berlin Heidelberg
Koh-Tan, H.H. C., McBride, M. W., McClure, J. D., Beattie, E., Young, B., Dominiczak, A. F., Graham, D. (2013) Interaction between chromosome 2 and 3 regulates pulse pressure in the stroke-prone spontaneously hypertensive rat Hypertension, 62, pp. 33-40. (doi: 10.1161/HYPERTENSIONAHA.111.00814)
Poppe, K.K., Squire, I.B., Whalley, G.A., Kober, L., McAlister, F. A., McMurray, J.J.V., Pocock, S., Earle, N.J., Berry, C., Doughty, R.N., Berry, C., Doughty, R., Meta-Analysis Global Group in Chronic Heart Failure, . (2013) Known and missing left ventricular ejection fraction and survival in patients with heart failure: a MAGGIC meta-analysis report European Journal of Heart Failure, 15, pp. 1220-1227. (doi: 10.1093/eurjhf/hft101)
Delles, C., Dominiczak, A. F. (2013) Metabolic alterations Springer
Welsh, P., Doolin, O., Willeit, P., Packard, C., Macfarlane, P., Cobbe, S., Gudnason, V., Di Angelantonio, E., Ford, I., Sattar, N. (2013) N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events: results from 15-year follow-up of WOSCOPS European Heart Journal, 34, pp. 443-450. (doi: 10.1093/eurheartj/ehs239)
Lang, N.N., Connelly, D.T. (2013) Novel oral anticoagulants for the prevention of thromboembolism in patients with atrial fibrillation Journal of the Royal College of Physicians of Edinburgh, 43, pp. 151-158. (doi: 10.4997/JRCPE.2013.213)
Smith, D., Nicholl, B., Cullen, B., Martin, D., Ul-Haq, Z., Evans, J., Gill, J., Roberts, B., Gallacher, J., Mackay, D., Hotopf, M., Deary, I., Craddock, N., Pell, J. (2013) Prevalence and characteristics of probable major depression and bipolar disorder within UK Biobank: cross-sectional study of 172,751 participants PLoS ONE, 8, pp. e75362. (doi: 10.1371/journal.pone.0075362)
Howard, L., MacKenzie, R. M., Pchelintsev, N. A., McBryan, T., McClure, J. D., McBride, M. W., Kane, N. M., Adams, P. D., Milligan, G., Baker, A. H. (2013) Profiling of transcriptional and epigenetic changes during directed endothelial differentiation of human embryonic stem cells identifies FOXA2 as a marker of early mesoderm commitment Stem Cell Research and Therapy, 4, pp. Art. 36. (doi: 10.1186/scrt192)
Currie, G., Delles, C. (2013) Proteinuria and its relation to cardiovascular disease International Journal of Nephrology and Renovascular Disease, 7, pp. 13-24. (doi: 10.2147/IJNRD.S40522)
Carty, D. M., Schiffer, E., Delles, C. (2013) Proteomics in hypertension Journal of Human Hypertension, 27, pp. 211-216. (doi: 10.1038/jhh.2012.30)
Singh, A., Ford, I., Greenwood, J.P., Khan, J.N., Uddin, A., Berry, C., Neubauer, S., Prendergast, B., Jerosch-Herold, M., Williams, B., Samani, N.J., McCann, G.P. (2013) Rationale and design of the PRognostic Importance of MIcrovascular Dysfunction in asymptomatic patients with Aortic Stenosis (PRIMID-AS): a multicentre observational study with blinded investigations BMJ Open, 3, pp. e004348-e004348. (doi: 10.1136/bmjopen-2013-004348)
Celis-Morales, C. A., Ghouri, N., Bailey, M.E.S., Sattar, N., Gill, J. M.R. (2013) Should physical activity recommendations be ethnicity-specific? Evidence from a cross-sectional study of south Asian and European men PLoS ONE, 8, pp. e82568. (doi: 10.1371/journal.pone.0082568)
Wijsman, L.W., de Craen, A.J.M., Trompet, S., Gussekloo, J., Stott, D.J., Rodondi, N., Welsh, P., Jukema, J.W., Westendorp, R.G.J., Mooijaart, S.P. (2013) Subclinical thyroid dysfunction and cognitive decline in old age PLoS ONE, 8, pp. e59199. (doi: 10.1371/journal.pone.0059199)
Kelly, A., Ghouri, I.A., Kemi, O.J., Bishop, M.J., Bernus, O., Fenton, F.H., Myles, R.C., Burton, F.L., Smith, G.L. (2013) Subepicardial action potential characteristics are a function of depth and activation sequence in isolated rabbit hearts Circulation: Arrhythmia and Electrophysiology, 6, pp. 809-817. (doi: 10.1161/CIRCEP.113.000334)
Elliott, E.B., McCarroll, D., Hasumi, H., Welsh, C.E., Panissidi, A., Jones, N.G., Rossor, C., Tait, A., Smith, G., Mottram, J.C., Morrison, L.J., Loughrey, C.M. (2013) T. brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes Cardiovascular Research, 100, pp. 325-335. (doi: 10.1093/cvr/cvt187)
Layland, J., Carrick, D., McEntegart, M., Ahmed, N., Payne, A., McClure, J., Sood, A., McGeoch, R., MacIsaac, A., Whitbourn, R., Wilson, A., Oldroyd, K., Berry, C. (2013) Vasodilatory capacity of the coronary microcirculation is preserved in selected patients with non-ST-segment-elevation myocardial infarction Circulation: Cardiovascular Interventions, 6, pp. 231-236. (doi: 10.1161/CIRCINTERVENTIONS.112.000180)
2012
Campbell, R.T., Jhund, P.S., Castagno, D., Hawkins, N.M., Petrie, M.C., McMurray, J.J.V. (2012) What have we learned about patients with heart failure and preserved ejection fraction from DIG-PEF, CHARM-Preserved, and I-PRESERVE? Journal of the American College of Cardiology, 60, pp. 2349-2356. (doi: 10.1016/j.jacc.2012.04.064)
Xu, H., Oliveira-Sales, E.B., McBride, F., Liu, B., Hewinson, J., Toward, M., Hendy, E.B., Graham, D., Dominiczak, A.F., Giannotta, M., Waki, H., Ascione, R., Paton, J.F.R., Kasparov, S. (2012) Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension Cardiovascular Research, 96, pp. 552-560. (doi: 10.1093/cvr/cvs273)
Welsh, P., Doolin, O., McConnachie, A., Boulton, E., McNeil, G., Macdonald, H., Hardcastle, A., Hart, C., Upton, M., Watt, G., Sattar, N. (2012) Circulating 250HD, dietary vitamin D, PTH, and calcium associations with incident cardiovascular disease and mortality: The MIDSPAN Family Study Journal of Clinical Endocrinology and Metabolism, 97, pp. 4578-4587. (doi: 10.1210/jc.2012-2272)
MacKenzie, R.M., Sandrim, V.C., Carty, D.M., McClure, J.D., Freeman, D.J., Dominiczak, A.F., McBride, M.W., Delles, C. (2012) Endothelial FOS expression and pre-eclampsia BJOG: An International Journal of Obstetrics and Gynaecology, 119, pp. 1564-1571. (doi: 10.1111/1471-0528.12016)
Ingle, L., Sloan, R., Carroll, S., Goode, K., Cleland, J. G., Clark, A. L. (2012) Influence of body mass on risk prediction during cardiopulmonary exercise testing in patients with chronic heart failure Experimental and Clinical Cardiology, 17, pp. 179-182.
Pepera, G. K., Sandercock, G. R., Sloan, R., Cleland, J. J.F., Ingle, L., Clark, A. L. (2012) Influence of step length on 6-minute walk test performance in patients with chronic heart failure Physiotherapy, 98, pp. 325-329. (doi: 10.1016/j.physio.2011.08.005)
Chick, H.E., Nowrouzi, A., Fronza, R., McDonald, R.A., Kane, N.M., Alba, R., Delles, C., Sessa, W.C., Schmidt, M., Thrasher, A.J., Baker, A.H. (2012) Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk Human Gene Therapy, 23, pp. 1247-1257. (doi: 10.1089/hum.2012.042)
Ord, E. N.J., Shirley, R., van Kralingen, J. C., Graves, A., McClure, J. D., Wilkinson, M., McCabe, C., Macrae, I. M., Work, L. M. (2012) Positive impact of pre-stroke surgery on survival following transient focal ischemia in hypertensive rats Journal of Neuroscience Methods, 211, pp. 305-308. (doi: 10.1016/j.jneumeth.2012.09.001)
Rho, R. W., Patton, K. K., Poole, J. E., Cleland, J. G., Shadman, R., Anand, I., Maggioni, A. P., Carson, P. E., Swedberg, K., Levy, W. C. (2012) Important differences in mode of death between men and women with heart failure who would qualify for a primary prevention implantable cardioverter-defibrillator Circulation, 126, pp. 2402-2407. (doi: 10.1161/CIRCULATIONAHA.111.069245)
Asselbergs, F.W., Guo, Y., van Iperen, E.P.A., Sivapalaratnam, S., Tragante, V., Lanktree, M.B., Lange, L.A., Almoguera, B., Appelman, Y.E., Barnard, J., Baumert, J., Beitelshees, A.L., Bhangale, T.R., Chen, Y.I., Gaunt, T.R., Gong, Y., Hopewell, J.C., Johnson, T., Kleber, M.E., Langaee, T.Y., Li, M., Li, Y.R., Liu, K., McDonough, C.W., Meijs, M.F.L., Middelberg, R.P.S., Musunuru, K., Nelson, C.P., O’Connell, J.R., Padmanabhan, S., Pankow, J.S., Pankratz, N., Rafelt, S., Rajagopalan, R., Romaine, S.P.R., Schork, N.J., Shaffer, J., Shen, H., Smith, E.N., Tischfield, S.E., van der Most, P.J., van Vliet-Ostaptchouk, J.V., Verweij, N., Volcik, K.A., Zhang, L., Bailey, K.R., Bailey, K.M., Bauer, F., Boer, J.M.A., Braund, P.S., Burt, A., Burton, P.R., Buxbaum, S.G., Chen, W., Cooper-DeHoff, R.M., Cupples, L.A., deJong, J.S., Delles, C., Duggan, D., Fornage, M., Furlong, C.E., Glazer, N., Gums, J.G., Hastie, C., Holmes, M.V., Illig, T., Kirkland, S.A., Kivimaki, M., Klein, R., Klein, B.E., Kooperberg, C., Kottke-Marchant, K., Kumari, M., LaCroix, A.Z., Mallela, L., Murugesan, G., Ordovas, J., Ouwehand, W.H., Post, W.S., Saxena, R., Scharnagl, H., Schreiner, P.J., Shah, T., Shields, D.C., Shimbo, D., Srinivasan, S.R., Stolk, R.P., Swerdlow, D.I., Taylor, H.A., Topol, E.J., Toskala, E., van Pelt, J.L., van Setten, J., Yusuf, S., Whittaker, J.C., Zwinderman, A.H., Anand, S.S., Balmforth, A.J., Berenson, G.S., Bezzina, C.R., Boehm, B.O., Boerwinkle, E., Casas, J.P., Caulfield, M.J., Clarke, R., Connell, J.M., Cruickshanks, K.J., Davidson, K.W., Day, I.N.M., de Bakker, P.I.W., Doevendans, P.A., Dominiczak, A.F., Hall, A.S., Hartman, C.A., Hengstenberg, C., Hillege, H.L., Hofker, M.H., Humphries, S.E., Jarvik, G.P., Johnson, J.A., Kaess, B.M., Kathiresan, S., Koenig, W., Lawlor, D.A., März, W., Melander, O., Mitchell, B.D., Montgomery, G.W., Munroe, P.B., Murray, S.S., Newhouse, S.J., Onland-Moret, N.C., Poulter, N., Psaty, B., Redline, S., Rich, S.S., Rotter, J.I., Schunkert, H., Sever, P., Shuldiner, A.R., Silverstein, R.L., Stanton, A., Thorand, B., Trip, M.D., Tsai, M.Y., van der Harst, P., van der Schoot, E., van der Schouw, Y.T., Verschuren, W.M.M., Watkins, H., Wilde, A.A.M., Wolffenbuttel, B.H.R., Whitfield, J.B., Hovingh, G.K., Ballantyne, C.M., Wijmenga, C., Reilly, M.P., Martin, N.G., Wilson, J.G., Rader, D.J., Samani, N.J., Reiner, A.P., Hegele, R.A., Kastelein, J.J.P., Hingorani, A.D., Talmud, P.J., Hakonarson, H., Elbers, C.C., Keating, B.J., Drenos, F. (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci American Journal of Human Genetics, 91, pp. 823-838. (doi: 10.1016/j.ajhg.2012.08.032)
Freel, E. M., Mark, P. B., Weir, R. A.P., McQuarrie, E. P., Allan, K., Dargie, H. J., McClure, J. D., Jardine, A. G., Davies, E., Connell, J. M.C. (2012) Demonstration of blood pressure-independent noninfarct myocardial fibrosis in primary aldosteronism: a cardiac magnetic resonance imaging study Circulation: Cardiovascular Imaging, 5, pp. 740-747. (doi: 10.1161/CIRCIMAGING.112.974576)
Pellicori, P., Sherwi, N., Khaleva, O., Wong, K., Cleland, J. G.F. (2012) An atrial mass: the value of echocardiographic three-dimensional reconstruction Journal of Cardiovascular Medicine, 13, pp. 769-770. (doi: 10.2459/JCM.0b013e32834917ed)
Pettit, S.J., Jhund, P.S., Hawkins, N.M., Gardner, R.S., Haj-Yahia, S., McMurray, J.J.V., Petrie, M.C. (2012) How small is too small? A systematic review of center volume and outcome after cardiac transplantation Circulation: Cardiovascular Quality and Outcomes, 5, pp. 783-790. (doi: 10.1161/CIRCOUTCOMES.112.966630)
Buga, L., Cleland, J. G.F. (2012) Increasing knowledge and changing views in cardiac resynchronization therapy Heart Failure Reviews, 17, pp. 721-725. (doi: 10.1007/s10741-011-9281-z)
MacRitchie, N., Grassia, G., Sabir, S. R., Maddaluno, M., Welsh, P., Sattar, N., Ialenti, A., Kurowska-Stolarska, M., McInnes, I. B., Brewer, J. M., Garside, P., Maffia, P. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice Arteriosclerosis, Thrombosis, and Vascular Biology, 32, pp. 2569-2579. (doi: 10.1161/ATVBAHA.112.251314)
Gao, H., Carrick, D., Kadir, K., McComb, C., Foster, J., Soraghan, J., Luo, X., Berry, C. (2012) Semi-automatic OEDEMA quantification from direct T2 map cardiac MRI Heart, 98, pp. A7-A7. (doi: 10.1136/heartjnl-2012-302951.022)
Cleland, J. G.F., Ghio, S. (2012) The determinants of clinical outcome and clinical response to CRT are not the same Heart Failure Reviews, 17, pp. 755-766. (doi: 10.1007/s10741-011-9268-9)
Miller, A. M., Purves, D., McConnachie, A., Asquith, D. L., Batty, G. D., Burns, H., Cavanagh, J., Ford, I., McLean, J. S., Packard, C. J., Shiels, P. G., Turner, H., Velupillai, Y. N., Deans, K. A., Welsh, P., McInnes, I. B., Sattar, N. (2012) Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? PLoS ONE, 7, pp. e47830. (doi: 10.1371/journal.pone.0047830)
Cheng, H., Smith, G.L., Orchard, C.H., Hancox, J.C., Burton, F.L. (2012) Inhibition of sarcoplasmic reticulum Ca2+-ATPase decreases atrioventricular node-paced heart rate in rabbits Experimental Physiology, 97, pp. 1131-1139. (doi: 10.1113/expphysiol.2012.065110)
Manzano, L., Escobar, C., Cleland, J. G.F., Flather, M. (2012) Diagnosis of elderly patients with heart failure European Journal of Heart Failure, 14, pp. 1097-1103. (doi: 10.1093/eurjhf/hfs109)
Cleland, J. G.F., Clark, A. L. (2012) Heart failure—does it matter whether LVEF is reduced? Lancet, 380, pp. 1363-1365. (doi: 10.1016/S0140-6736(12)61349-X)
Rea, P. M., McClure, J. D. (2012) Student authored and critiqued multiple choice questions benefit examination performance in anatomy – a pilot study Practice and Evidence of Scholarship of Teaching and Learning in Higher Education, 7, pp. 63-78.
Feinkohl, I., Sattar, N., Welsh, P., Reynolds, R. M., Deary, I. J., Strachan, M. W.J., Price, J. F. (2012) Association of N-terminal pro-brain natriuretic peptide with cognitive function and depression in elderly people with type 2 diabetes PLoS ONE, 7, pp. e44569. (doi: 10.1371/journal.pone.0044569)
Workman, A.J., Marshall, G.E., Rankin, A.C., Smith, G.L., Dempster, J. (2012) Transient outward K+ current (ITO) reduction prolongs action potentials and promotes afterdepolarisations: a dynamic-clamp study in human and rabbit cardiac atrial myocytes Journal of Physiology, 590, pp. 4289-4305. (doi: 10.1113/jphysiol.2012.235986)
Daubert, J.-C., Saxon, L., Adamson, P. B., Auricchio, A., Berger, R. D., Beshai, J. F., Breithard, O., Brignole, M., Cleland, J., DeLurgio, D. B., Dickstein, K., Exner, D. V., Gold, M., Grimm, R. A., Hayes, D. L., Israel, C., Leclercq, C., Linde, C., Lindenfeld, J., Merkely, B., Mont, L., Murgatroyd, F., Prinzen, F., Saba, S. F., Shinbane, J. S., Singh, J., Tang, A. S., Vardas, P. E., Wilkoff, B. L., Zamorano, J. L. (2012) 2012 EHRA/HRS expert consensus statement on cardiac resynchronization therapy in heart failure: implant and follow-up recommendations and management Heart Rhythm, 9, pp. 1524-1576. (doi: 10.1016/j.hrthm.2012.07.025)
Lang, N.N., Newby, D.E. (2012) Cardiac compression causing fatal acute ST-segment elevation myocardial infarction QJM: An International Journal of Medicine, 105, pp. 883-885. (doi: 10.1093/qjmed/hcr131)
Paul, L., Jeemon, P., Hewitt, J., McCallum, L., Higgins, P., Walters, M., McClure, J., Dawson, J., Meredith, P., Jones, G.C., Muir, S., Dominiczak, A.F., Lowe, G., McInnes, G.T., Padmanabhan, S. (2012) Hematocrit predicts long-term mortality in a nonlinear and sex-specific manner in hypertensive adults Hypertension, 60, pp. 631-638. (doi: 10.1161/HYPERTENSIONAHA.112.191510)
Reid, E., Graham, D., Lopez-Gonzalez, M. R., Holmes, W. M., Macrae, I. M., McCabe, C. (2012) Penumbra detection using PWI/DWI mismatch MRI in a rat stroke model with and without comorbidity: comparison of methods Journal of Cerebral Blood Flow and Metabolism, 32, pp. 1765-1777. (doi: 10.1038/jcbfm.2012.69)
Alam, S. R., Shah, A. S.V., Richards, J., Lang, N. N., Barnes, G., Joshi, N., MacGillivray, T., McKillop, G., Mirasadraee, S., Payne, J., Fox, K. A.A., Henriksen, P., Newby, D. E., Semple, S. I.K. (2012) Ultrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experience Circulation: Cardiovascular Imaging, 5, pp. 559-565. (doi: 10.1161/CIRCIMAGING.112.974907)
Storrow, A. B., Lindsell, C. J., Collins, S. P., Diercks, D. B., Filippatos, G. S., Hiestand, B. C., Hollander, J. E., Kirk, J. D., Levy, P. D., Miller, C. D., Naftilan, A. J., Nowak, R. M., Pang, P. S., Peacock, W. F., Gheorghiade, M., Cleland, J. G.F. (2012) Standardized reporting criteria for studies evaluating suspected acute heart failure syndromes in the emergency department Journal of the American College of Cardiology, 60, pp. 822-832. (doi: 10.1016/j.jacc.2012.03.072)
Mischak, H., Ioannidis, J. P.A., Argiles, A., Attwood, T. K., Bongcam-Rudloff, E., Broenstrup, M., Charonis, A., Chrousos, G. P., Delles, C., Dominiczak, A., Dylag, T., Ehrich, J., Egido, J., Findeisen, P., Jankowski, J., Johnson, R. W., Julien, B. A., Lankisch, T., Leung, H., Maahs, D., Magni, F., Manns, M. P., Manolis, E., Mayer, G., Navis, G., Novak, J., Ortiz, A., Persson, F., Peter, K., Riese, H. H., Rossing, P., Sattar, N., Spasovski, G., Thongboonkerd, V., Vanholder, R., Schanstra, J. P., Vlahou, A. (2012) Implementation of proteomic biomarkers: making it work European Journal of Clinical Investigation, 42, pp. 1027-1036. (doi: 10.1111/j.1365-2362.2012.02674.x)
Kohan, D. E., Cleland, J. G., Rubin, L. J., Theodorescu, D., Barton, M. (2012) Clinical trials with endothelin receptor antagonists: What went wrong and where can we improve? Life Sciences, 91, pp. 528-539. (doi: 10.1016/j.lfs.2012.07.034)
Payne, A. R., Berry, C., Doolin, O., McEntegart, M., Petrie, M. C., Lindsay, M. M., Hood, S., Carrick, D., Tzemos, N., Weale, P., McComb, C., Foster, J., Ford, I., Oldroyd, K. G. (2012) Microvascular resistance predicts myocardial salvage and infarct characteristics in ST-elevation myocardial infarction Journal of the American Heart Association, 1, pp. e002246. (doi: 10.1161/JAHA.112.002246)
Knox, S., Welsh, P., Bezlyak, V., McConnachie, A., Boulton, E., Deans, K.A., Ford, I., Batty, G.D., Burns, H., Cavanagh, J., Millar, K., McInnes, I.B., Velupillai, Y., Shiels, P., Tannahill, C., Packard, C.J., Wallace, A.M., Sattar, N. (2012) 25-hydroxyvitamin D is lower in deprived groups, but is not associated with carotid intima media thickness or plaques: results from pSoBid Atherosclerosis, 223, pp. 437-441. (doi: 10.1016/j.atherosclerosis.2012.05.001)
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Oxberry, S. G., Bland, J. M., Clark, A. L., Cleland, J. G.F., Johnson, M. J. (2012) Minimally clinically important difference in chronic breathlessness: Every little helps American Heart Journal, 164, pp. 229-235. (doi: 10.1016/j.ahj.2012.05.003)
McInnes, I., Lee, J.S., Thompson, L., Giles, J.T., Bathton, J.M., Salmon, J.E., Beaulieu, A.D., Codding, C.E., Delles, C., Sattar, N. (2012) The effects of tocilizumab treatment on lipids and inflammatory/prothrombotic markers in patients (pts) with rheumatoid arthritis (RA): data from the randomized, controlled, measure study European Heart Journal, 33, pp. 281. (doi: 10.1093/eurheartj/ehs281)
Caruso, P., Dempsie, Y., Stevens, H. C., McDonald, R. A., Long, L., Lu, R., White, K., Mair, K. M., McClure, J. D., Southwood, M., Upton, P., Xin, M., van Rooij, E., Olson, E. N., Morrell, N. W., MacLean, M. R., Baker, A. H. (2012) A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples Circulation Research, 111, pp. 290-300. (doi: 10.1161/CIRCRESAHA.112.267591)
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The Glasgow Biomarker Research Unit (GlasBRU) is a facility that conducts blood and urine tests for research purposes. This includes conducting tests that are often routinely conducted as part of clinical care, as well as more experimental blood tests. We then use that information to change our understanding of the causes and consequences of cardiometabolic disease, and the way we use blood tests in real clinical practice.
How do we conduct research?
We have large biobanks of blood samples from different populations and studies that we use, or we use existing data from studies that are available to healthcare researchers such as UK Biobank, SAIL, and NHS Safehaven data. For example,
- We conduct blood tests in ongoing clinical trials to better understand the consequences of interventions like weight loss or new pharmacological treatments for heart failure.
- We conduct blood tests in population-based studies (observational studies) to better understand who develops cardiometabolic diseases and why, or what the biological consequences of health and disease are.
- We use information from blood tests to understand who is at risk of disease, and then use that information to better understand which patients might be screened for disease, allowing early intervention or prevention in clinical practice.
Our collaborators and funders include researchers from across the world, industrial biomarker companies, industrial pharmacological companies, as well as charitable and UKRI funders.
Impact
Our world-class research has had an impact in a wide range of conditions and studies including:
- Weight Loss in The Diabetes Remission Clinical Trial (DiRECT)
- Heart Failure treatments (such as the DAPA-HF trial)
- Cardiovascular risk screening studies (in studies such as UK Biobank and Generation Scotland Family Study)
UK Biobank: www.ukbiobank.ac.uk
WoS SafeHaven: www.nhsggc.scot/hospitals-services/services-a-to-z/west-of-scotland-safe-haven/
Generation Scotland: www.ed.ac.uk/generation-scotland