UofG announces research collaboration with Lilly to discover potential new drug targets
Mon, 15 Feb 2021 00:01:57 GMT
UofG-led arthritis research centre creates new generation of scientists
Mon, 12 Oct 2020 00:00:00 BST
Glasgow team will transform bowel cancer screening into a precision medicine tool using AI
Fri, 03 Jul 2020 09:01:00 BST
Key funding
- A Chemical Genetic Approach to Exploring Novel Therapeutic Space for Colorectal Cancer; National Institutes ofHealth (NIH), £104k (2022-23)
- Understanding the communication between the osteoblast lineage and articular cartilage chondrocytes; Versus Arthritis, £508k (2022-27).
- Precision-Panc: a dynamic therapeutic development platform for pancreatic cancer; Cancer Resaerch UK, £30k (2022-23).
- Acousto-activated sonoluminescent drug delivery for future precision medicine; Engineering and Physical Sciences Research Council, £99k (2022-23).
- Target validation of caspase proteases to improve colorectal cancer treatment; Cancer Research UK, £76k (2022-23).
- How do senescent stromal cells subvert the treatment response in acute lymphoblastic leukaemia?; Medical Research Council, £376k (2021-24)
Research news
- Glasgow scientists working to develop new immunotherapy for breast cancer
- Iron test could improve outcomes for heart patients
- New Scottish study to "REACH" people with heart failure at home
- Identifying frailty should be a routine part of Diabetes care
- UofG researchers report how novel diabetes drugs work to improve the prognosis for patients with heart failure
- Scientists develop new 'precision medicine' approach to treating damaged DNA in pancreatic cancer
Key publications
- Effect of Empagliflozin on Left Ventricular Volumes in Patients with Type 2 Diabetes, or Prediabetes, and Heart Failure with Reduced Ejection Fraction (SUGAR-DM-HF). Circulation (2020).
- Frailty measurement, prevalence, incidence, and clinical implications in people with diabetes: a systematic review and study-level meta-analysis. The Lancet Health Longevity (2020).
- Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. Nature Medicine (2020).
- Pan-cancer analysis of whole genomes. Nature Medicine (2020).
- Pathophysiological regulation of lung function by the free fatty acid receptor FFA4. Science Translational Medicine (2020).
Scotland has a high incidence of chronic disease. There are rising numbers of people living with multiple long-term disorders, impacting on quality of life and increasing costs to the NHS.
The University’s Clinical Innovation Zone at the Queen Elizabeth University Hospital (QEUH) campus is now Scotland’s focal point for the implementation of precision medicine. The Zone is home to the Precision Medicine Scotland Innovation Centre (PMS-IC, formerly the Stratified Medicine Scotland Innovation Centre).
Precision Medicine is an approach which enables doctors and researchers to identify and develop treatments that are effective for particular groups of patients, using advanced genomic, imaging and information technologies. Precision medicine will ensure that the right patient gets the right treatment at the right time, and will provide safer and more cost-effective treatments.
Partnering with NHS Greater Glasgow & Clyde, the University of Glasgow has driven Scotland’s vision in precision medicine, including the development of over £80m infrastructure to support precision medicine clinical trials at the QEUH. Our £32m Imaging Centre of Excellence (ICE) includes Scotland’s only 7 Tesla MRI scanner, an ultra-high resolution scanner, which is the first of its kind fully integrated within a clinical site in the UK. ICE will drive the development of imaging technology to understand and benefit diseases such as stroke, brain tumours and multiple sclerosis.
The University is one of Innovate UK’s Precision Medicine Centres of Excellence and our ambition is to be a global centre of excellence for chronic disease, precision medicine and imaging. Capitalising on our investment in infrastructure and biomedical researchers to drive international research excellence and patient benefits, and deliver economic benefit for Scotland and the UK.
Meet our academic ambassadors
- Professor Dame Anna Dominiczak
- Dr Carol Clugston
- Professor Jeff Evans
- Professor Frances Mair
- Professor Iain McInnes
- Professor Rhian Touyz
Supporting the United Nations Sustainable Development Goals:
Find out more: Sustainable Development Goals