Dr Paul Prentice

  • Lecturer (Systems Power and Energy)

telephone: 01413308754
email: Paul.Prentice@glasgow.ac.uk

Research interests

 

Paul's current research is aimed at developing a fundamental understanding of acoustic cavitation, that is bubble activity, driven by focused ultrasound.

This is an extremely energetic, often violent phenomenon, as bubbles in a liquid (or tissue) interact strongly with the pressure fluctuations of an intense ultrasound field.

We use ultra-fast framing cameras to image cavitation dynamics, and a range of devices to acoustically detect (listen to) the activity.

 

Ultimately, we hope to develop control strategies, automated and in real time (sub-millisecond), to harness the power of cavitation for medical and industrial applications.

 

In summary, if it's a bubble, Paul is interested!

 

To find out more, visit the group website at cavlab.co.uk

 

Awards

  • National Instruments Global Engineering Impact Award (Advanced Research category) runner-up, 2014
    • Project case study: Ultra-rapid and autonomous feedback control loop for cavitation in focused ultrasound (joint with Diagnostic Sonar Ltd.)

 

  • TENOVUS Scotland Sir Robin McLellan Prize, 2014

 

Grants

As Principal Investigator

  • European Research Council (ERC) Starting Grant

          TheraCav: harnessing cavitation for therapy

          €1.45M 2013-2018

  • SUPA Industrial Placement (with Diagnostic Sonar Ltd.)

          Autonomous and ultra-rapid cavitation control feedback loop

          £26.5k 2013-2014

  • Tenovus Scotland 

          Harnessing bubble-power for cancer therapy

          £9.5k 2012-2013

  • Norwegian Research Council (NRC) Yggdrasil mobility grant (to Bergen University)

          High-speed flourescence migration imaging

          NK23.5k 2011-2012

 

As Co-Investigator

  • European Union FP7 Industry-Academia Partnership Project

          Ultrasound activiated nanoencapsulated targetted drug delivery and tumour cell poration

          €2.07M 2009-2013

 

 

Supervision

As primary supervisor

PhD students:

  • Mr Kristoffer Johansen
  • Miss Miriam Garcia Jimenez

 

Research Assistant:

  • Dr Jae Hee Song

 

Graduated:

  • Dr Keith Johnston (currently a lecturer at the University of Dundee)
  • Dr Bjoern Gerold (currently a Marie Curie Research Fellow at Theraclion, France)

Publications

List by: Type | Date

Jump to: 2017 | 2016 | 2014 | 2013 | 2012 | 2011 | 2010 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003
Number of items: 33.

2017

Song, J. H., Johansen, K. and Prentice, P. (2017) Covert cavitation: Spectral peak suppression in the acoustic emissions from spatially configured nucleations. Journal of the Acoustical Society of America, 141(3), EL216. (doi:10.1121/1.4977236)

Johansen, K., Song, J. H., Johnston, K. and Prentice, P. (2017) Deconvolution of acoustically detected bubble-collapse shock waves. Ultrasonics, 73, pp. 144-153. (doi:10.1016/j.ultras.2016.09.007) (PMID:27657479)

2016

Song, J. H., Johansen, K. and Prentice, P. (2016) An analysis of the acoustic cavitation noise spectrum: The role of periodic shock waves. Journal of the Acoustical Society of America, 140, pp. 2494-2505. (doi:10.1121/1.4964633)

Fiabane, J., Prentice, P. and Pancholi, K. (2016) High yielding microbubble production method. BioMed Research International, 2016, 3572827. (doi:10.1155/2016/3572827) (PMID:27034935) (PMCID:PMC4789381)

2014

Johnston, K., Tapia-Siles, C., Gerold, B., Postema, M., Cochran, S. , Cuschieri, A. and Prentice, P. (2014) Periodic shock-emission from acoustically driven cavitation clouds: a source of the subharmonic signal. Ultrasonics, 54(8), pp. 2151-2158. (doi:10.1016/j.ultras.2014.06.011) (PMID:25015000)

Johnston, K., Cochran, S. and Prentice, P. (2014) Non-linear cavitation cloud oscillations in High-Intensity Focused Ultrasound. In: 2014 IEEE International Ultrasonics Symposium (IUS), Chicago, IL, USA, 3-6 Sep 2014, pp. 373-376. (doi:10.1109/ULTSYM.2014.0092)

Johnston, K., Prentice, P. and Gerold, B. (2014) Cavitation Cloud Translation in Focused Ultrasound. In: 2014 IEEE International Ultrasonics Symposium, Chicago, IL, 3-6 Sept 2014, pp. 61-64. (doi:10.1109/ULTSYM.2014.0016)

2013

Gerold, B., Rachmilevitch, I. and Prentice, P. (2013) Bifurcation of ensemble oscillations and acoustic emissions from early stage cavitation clouds in focused ultrasound. New Journal of Physics, 15(3), 033044. (doi:10.1088/1367-2630/15/3/033044)

2012

Gerold, B., Glynne-Jones, P., McDougall, C., McGloin, D., Cochran, S. , Melzer, A. and Prentice, P. (2012) Directed jetting from collapsing cavities exposed to focused ultrasound. Applied Physics Letters, 100(2), 024104. (doi:10.1063/1.3676414)

Hoskins, C., Min, Y., Gueorguieva, M., McDougall, C., Volovick, A., Prentice, P. , Wang, Z., Melzer, A., Cuschieri, A. and Wang, L. (2012) Hybrid gold-iron oxide nanoparticles as a multifunctional platform for biomedical application. Journal of Nanobiotechnology, 10(1), p. 27. (doi:10.1186/1477-3155-10-27) (PMID:22731703) (PMCID:PMC3448509)

Melzer, A., Cochran, S. , Prentice, P. , MacDonald, M. P., Wang, Z. and Cuschieri, A. (2012) The importance of physics to progress in medical treatment. Lancet, 379(9825), pp. 1534-1543. (doi:10.1016/S0140-6736(12)60428-0) (PMID:22516559)

Gerold, B. et al. (2012) Applicator for in-vitro ultrasound-activated targeted drug delivery. In: 11th International Symposium on Therapeutic Ultrasound. 2012 AIP Conference Proceedings, New York, NY, 11–13 April 2011, pp. 100-105. (doi:10.1063/1.4757318)

2011

Gourevich, D. et al. (2011) Ultrasound activated nano-encapsulated targeted drug delivery and tumour cell poration. pp. 135-144. (doi:10.1007/978-94-007-2555-3_13) (PMID:22101719)

Gerold, B., Kotopoulis, S., McDougall, C., McGloin, D., Postema, M. and Prentice, P. (2011) Laser-nucleated acoustic cavitation in focused ultrasound. Review of Scientific Instruments, 82(4), 044902. (doi:10.1063/1.3579499) (PMID:21529030)

2010

Oraevsky, A. A., Prentice, P. , Wang, L. V., Zolotovskaya, S. and Rafailov, E. (2010) Novel Laser-Induced Cavitation: The Constrained Ring Bubble. In: Photons Plus Ultrasound: Imaging and Sensing, San Francisco, CA, USA, 23 Jan 2010, 75642G. (doi:10.1117/12.837463)

2008

Burns, J.M., Prentice, P.A. and Campbell, P. (2008) Preliminary Observations on Sonoporated Cells Via Real-Time Fluorescence-Guided Atomic Force Microscopy. In: Spring Conference of the Institute of Acoustics 2008: Widening Horizons in Acoustics, Reading, England, 10-11 Apr 2008, pp. 386-390. ISBN 9781605601427

Prentice, P.A. and Campbell, P. A. (2008) Application of Optical Trapping for Cavitation Studies. In: Optical Trapping and Optical Micromanipulation Optical Trapping and Optical Micromanipulation, San Francisco, CA, USA, 10 Aug 2008, 70381N. (doi:10.1117/12.794192)

Prentice, P.A. and Campbell, P.A. (2008) Observing Ultrasound Stimulated Microbubble Dynamics at MHz Framing Rates. In: 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vancouver, BC, Canada, 20-25 Aug 2008, pp. 4463-4466. ISBN 9781424418145 (doi:10.1109/IEMBS.2008.4650202)

2007

Burns, J. M., Prentice, P.A. and Campbell, P. A. (2007) 9B-2 Microbubble Interactions at High Mechanical Index: Ultrasound Stimulated Behaviour of SonoVue from Optically Predefined 'Stand-Off' Positions. IEEE Ultrasonics Symposium, New York, NY, USA, 28-31 Oct 2007. pp. 761-764. ISBN 9781424413843 (doi:10.1109/ULTSYM.2007.195)

Campbell, P. and Prentice, P. (2007) Optimization and constraints in sonolithography. MRS Proceedings, 1059, (doi:10.1557/PROC-1059-KK10-39)

Prentice, P. A. and Campbell, P. A. (2007) Ultrasound-Stimulated Mutual Interaction Forces between Optically Configured Micro-Bubble Pairs. In: 6th International Symposium on Therapeutic Ultrasound, Oxford, England, 30 Aug - 2 Sep 2007, pp. 212-218. ISBN 9780735404199 (doi:10.1063/1.2744275)

Prentice, P. A. and Campbell, P. A. (2007) Ultrasound-Stimulated Mutual Interaction Forces between Optically Configured Micro-Bubble Pairs. In: 6th International Symposium on Therapeutic Ultrasound, Oxford, England, 30 Aug - 2 Sep 2007, pp. 212-218. ISBN 9780735404199 (doi:10.1063/1.2744275)

2006

MacDonald, M.P., Prentice, P. and Dholakia, K. (2006) Optical vortices produced by diffraction from dislocations in two-dimensional colloidal crystals. New Journal of Physics, 8(10), p. 257. (doi:10.1088/1367-2630/8/10/257)

Burns, J.M., Prentice, P.A. , Cuschieri, A. and Campbell, P.A. (2006) Modelling the Microscopic Mechanisms of Sonoporation. In: NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech, Boston, MA, USA, 7-11 May 2006, pp. 333-336. ISBN 0976798573

Prentice, P.A. , Burns, J.M., Cuschieri, A. and Campbell, P.A. (2006) Microscopic Mechanisms of Sonoporation. In: NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech, Boston, MA, USA, 7-11 May 2006, pp. 373-376. ISBN 0976798573

Prentice, P. (2006) Experimental Observation of Cell Membrane Rupture by Microbubble Cavitation. In: Spring Conference Futures in Acoustics 2006: Today's Research - Tomorrow's Careers, Southampton, England, 2-4 Apr 2006, ISBN 9781604236941

2005

Prentice, P. , Cuschieri, A., Dholakia, K., Prausnitz, M. and Campbell, P. (2005) Membrane disruption by optically controlled microbubble cavitation. Nature Physics, 1(2), pp. 107-110. (doi:10.1038/nphys148)

MacDonald, M. P., Prentice, P. and Dholakia, K. (2005) Colloidal Holography and Crystal Dislocations. In: Optical Trapping and Optical Micromanipulation II, Bellingham, WA, USA, 31 Jul - 4 Aug 2005, p. 593017. (doi:10.1117/12.614843)

Prentice, P.A. , Burns, J.M., McLean, D., Cuschieri, A., Sibbett, W. and Campbell, P.A. (2005) Ultra High Speed Observations Of Cavitation Derived Microjetting Phenomena. In: 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, Kahuku, HI, USA, 12-15 May 2005, pp. 160-161. ISBN 0780387112 (doi:10.1109/MMB.2005.1548413)

Prentice, P.A. , McLean, D., Cuschieri, A., Dholakia, K. and Campbell, P.A. (2005) Spatially Controlled Sonoporation of Prostate Cancer Cells Via Ultrasound Activated Microbubble Cavitation. In: 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, Kahuku, HI, USA, 12-15 May 2005, pp. 158-159. ISBN 0780387112 (doi:10.1109/MMB.2005.1548412)

Prentice, P. , MacDonald, M. P., Cuschieri, A., Dholakia, K. and Campbell, P. (2005) Real Time Observation Of The Ultrasound Stimulated Disintegration Of Optically Trapped Microbubbles In Proximity To Biological Cells. In: Optical Trapping and Optical Micromanipulation II, Bellingham, WA, USA, 31 Jul - 4 Aug 2005, 59300H. (doi:10.1117/12.615012)

2004

Prentice, P.A. , MacDonald, M.P., Frank, T.G., Cuschieri, A., Spalding, G.C., Sibbett, W., Campbell, P.A. and Dholakia, K. (2004) Manipulation and filtration of low index particles with holographic Laguerre-Gaussian optical trap arrays. Optics Express, 12(4), pp. 593-600. (doi:10.1364/OPEX.12.000593)

2003

Prentice, P. (2003) Adventures of a tough teacher. Physics World, 16(4), p. 47. (doi:10.1088/2058-7058/16/4/44)

This list was generated on Wed Oct 18 16:13:48 2017 BST.
Number of items: 33.

Articles

Song, J. H., Johansen, K. and Prentice, P. (2017) Covert cavitation: Spectral peak suppression in the acoustic emissions from spatially configured nucleations. Journal of the Acoustical Society of America, 141(3), EL216. (doi:10.1121/1.4977236)

Johansen, K., Song, J. H., Johnston, K. and Prentice, P. (2017) Deconvolution of acoustically detected bubble-collapse shock waves. Ultrasonics, 73, pp. 144-153. (doi:10.1016/j.ultras.2016.09.007) (PMID:27657479)

Song, J. H., Johansen, K. and Prentice, P. (2016) An analysis of the acoustic cavitation noise spectrum: The role of periodic shock waves. Journal of the Acoustical Society of America, 140, pp. 2494-2505. (doi:10.1121/1.4964633)

Fiabane, J., Prentice, P. and Pancholi, K. (2016) High yielding microbubble production method. BioMed Research International, 2016, 3572827. (doi:10.1155/2016/3572827) (PMID:27034935) (PMCID:PMC4789381)

Johnston, K., Tapia-Siles, C., Gerold, B., Postema, M., Cochran, S. , Cuschieri, A. and Prentice, P. (2014) Periodic shock-emission from acoustically driven cavitation clouds: a source of the subharmonic signal. Ultrasonics, 54(8), pp. 2151-2158. (doi:10.1016/j.ultras.2014.06.011) (PMID:25015000)

Gerold, B., Rachmilevitch, I. and Prentice, P. (2013) Bifurcation of ensemble oscillations and acoustic emissions from early stage cavitation clouds in focused ultrasound. New Journal of Physics, 15(3), 033044. (doi:10.1088/1367-2630/15/3/033044)

Gerold, B., Glynne-Jones, P., McDougall, C., McGloin, D., Cochran, S. , Melzer, A. and Prentice, P. (2012) Directed jetting from collapsing cavities exposed to focused ultrasound. Applied Physics Letters, 100(2), 024104. (doi:10.1063/1.3676414)

Hoskins, C., Min, Y., Gueorguieva, M., McDougall, C., Volovick, A., Prentice, P. , Wang, Z., Melzer, A., Cuschieri, A. and Wang, L. (2012) Hybrid gold-iron oxide nanoparticles as a multifunctional platform for biomedical application. Journal of Nanobiotechnology, 10(1), p. 27. (doi:10.1186/1477-3155-10-27) (PMID:22731703) (PMCID:PMC3448509)

Melzer, A., Cochran, S. , Prentice, P. , MacDonald, M. P., Wang, Z. and Cuschieri, A. (2012) The importance of physics to progress in medical treatment. Lancet, 379(9825), pp. 1534-1543. (doi:10.1016/S0140-6736(12)60428-0) (PMID:22516559)

Gourevich, D. et al. (2011) Ultrasound activated nano-encapsulated targeted drug delivery and tumour cell poration. pp. 135-144. (doi:10.1007/978-94-007-2555-3_13) (PMID:22101719)

Gerold, B., Kotopoulis, S., McDougall, C., McGloin, D., Postema, M. and Prentice, P. (2011) Laser-nucleated acoustic cavitation in focused ultrasound. Review of Scientific Instruments, 82(4), 044902. (doi:10.1063/1.3579499) (PMID:21529030)

Campbell, P. and Prentice, P. (2007) Optimization and constraints in sonolithography. MRS Proceedings, 1059, (doi:10.1557/PROC-1059-KK10-39)

MacDonald, M.P., Prentice, P. and Dholakia, K. (2006) Optical vortices produced by diffraction from dislocations in two-dimensional colloidal crystals. New Journal of Physics, 8(10), p. 257. (doi:10.1088/1367-2630/8/10/257)

Prentice, P. , Cuschieri, A., Dholakia, K., Prausnitz, M. and Campbell, P. (2005) Membrane disruption by optically controlled microbubble cavitation. Nature Physics, 1(2), pp. 107-110. (doi:10.1038/nphys148)

Prentice, P.A. , MacDonald, M.P., Frank, T.G., Cuschieri, A., Spalding, G.C., Sibbett, W., Campbell, P.A. and Dholakia, K. (2004) Manipulation and filtration of low index particles with holographic Laguerre-Gaussian optical trap arrays. Optics Express, 12(4), pp. 593-600. (doi:10.1364/OPEX.12.000593)

Prentice, P. (2003) Adventures of a tough teacher. Physics World, 16(4), p. 47. (doi:10.1088/2058-7058/16/4/44)

Conference or Workshop Item

Burns, J. M., Prentice, P.A. and Campbell, P. A. (2007) 9B-2 Microbubble Interactions at High Mechanical Index: Ultrasound Stimulated Behaviour of SonoVue from Optically Predefined 'Stand-Off' Positions. IEEE Ultrasonics Symposium, New York, NY, USA, 28-31 Oct 2007. pp. 761-764. ISBN 9781424413843 (doi:10.1109/ULTSYM.2007.195)

Conference Proceedings

Johnston, K., Cochran, S. and Prentice, P. (2014) Non-linear cavitation cloud oscillations in High-Intensity Focused Ultrasound. In: 2014 IEEE International Ultrasonics Symposium (IUS), Chicago, IL, USA, 3-6 Sep 2014, pp. 373-376. (doi:10.1109/ULTSYM.2014.0092)

Johnston, K., Prentice, P. and Gerold, B. (2014) Cavitation Cloud Translation in Focused Ultrasound. In: 2014 IEEE International Ultrasonics Symposium, Chicago, IL, 3-6 Sept 2014, pp. 61-64. (doi:10.1109/ULTSYM.2014.0016)

Gerold, B. et al. (2012) Applicator for in-vitro ultrasound-activated targeted drug delivery. In: 11th International Symposium on Therapeutic Ultrasound. 2012 AIP Conference Proceedings, New York, NY, 11–13 April 2011, pp. 100-105. (doi:10.1063/1.4757318)

Oraevsky, A. A., Prentice, P. , Wang, L. V., Zolotovskaya, S. and Rafailov, E. (2010) Novel Laser-Induced Cavitation: The Constrained Ring Bubble. In: Photons Plus Ultrasound: Imaging and Sensing, San Francisco, CA, USA, 23 Jan 2010, 75642G. (doi:10.1117/12.837463)

Burns, J.M., Prentice, P.A. and Campbell, P. (2008) Preliminary Observations on Sonoporated Cells Via Real-Time Fluorescence-Guided Atomic Force Microscopy. In: Spring Conference of the Institute of Acoustics 2008: Widening Horizons in Acoustics, Reading, England, 10-11 Apr 2008, pp. 386-390. ISBN 9781605601427

Prentice, P.A. and Campbell, P. A. (2008) Application of Optical Trapping for Cavitation Studies. In: Optical Trapping and Optical Micromanipulation Optical Trapping and Optical Micromanipulation, San Francisco, CA, USA, 10 Aug 2008, 70381N. (doi:10.1117/12.794192)

Prentice, P.A. and Campbell, P.A. (2008) Observing Ultrasound Stimulated Microbubble Dynamics at MHz Framing Rates. In: 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vancouver, BC, Canada, 20-25 Aug 2008, pp. 4463-4466. ISBN 9781424418145 (doi:10.1109/IEMBS.2008.4650202)

Prentice, P. A. and Campbell, P. A. (2007) Ultrasound-Stimulated Mutual Interaction Forces between Optically Configured Micro-Bubble Pairs. In: 6th International Symposium on Therapeutic Ultrasound, Oxford, England, 30 Aug - 2 Sep 2007, pp. 212-218. ISBN 9780735404199 (doi:10.1063/1.2744275)

Prentice, P. A. and Campbell, P. A. (2007) Ultrasound-Stimulated Mutual Interaction Forces between Optically Configured Micro-Bubble Pairs. In: 6th International Symposium on Therapeutic Ultrasound, Oxford, England, 30 Aug - 2 Sep 2007, pp. 212-218. ISBN 9780735404199 (doi:10.1063/1.2744275)

Burns, J.M., Prentice, P.A. , Cuschieri, A. and Campbell, P.A. (2006) Modelling the Microscopic Mechanisms of Sonoporation. In: NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech, Boston, MA, USA, 7-11 May 2006, pp. 333-336. ISBN 0976798573

Prentice, P.A. , Burns, J.M., Cuschieri, A. and Campbell, P.A. (2006) Microscopic Mechanisms of Sonoporation. In: NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech, Boston, MA, USA, 7-11 May 2006, pp. 373-376. ISBN 0976798573

Prentice, P. (2006) Experimental Observation of Cell Membrane Rupture by Microbubble Cavitation. In: Spring Conference Futures in Acoustics 2006: Today's Research - Tomorrow's Careers, Southampton, England, 2-4 Apr 2006, ISBN 9781604236941

MacDonald, M. P., Prentice, P. and Dholakia, K. (2005) Colloidal Holography and Crystal Dislocations. In: Optical Trapping and Optical Micromanipulation II, Bellingham, WA, USA, 31 Jul - 4 Aug 2005, p. 593017. (doi:10.1117/12.614843)

Prentice, P.A. , Burns, J.M., McLean, D., Cuschieri, A., Sibbett, W. and Campbell, P.A. (2005) Ultra High Speed Observations Of Cavitation Derived Microjetting Phenomena. In: 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, Kahuku, HI, USA, 12-15 May 2005, pp. 160-161. ISBN 0780387112 (doi:10.1109/MMB.2005.1548413)

Prentice, P.A. , McLean, D., Cuschieri, A., Dholakia, K. and Campbell, P.A. (2005) Spatially Controlled Sonoporation of Prostate Cancer Cells Via Ultrasound Activated Microbubble Cavitation. In: 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, Kahuku, HI, USA, 12-15 May 2005, pp. 158-159. ISBN 0780387112 (doi:10.1109/MMB.2005.1548412)

Prentice, P. , MacDonald, M. P., Cuschieri, A., Dholakia, K. and Campbell, P. (2005) Real Time Observation Of The Ultrasound Stimulated Disintegration Of Optically Trapped Microbubbles In Proximity To Biological Cells. In: Optical Trapping and Optical Micromanipulation II, Bellingham, WA, USA, 31 Jul - 4 Aug 2005, 59300H. (doi:10.1117/12.615012)

This list was generated on Wed Oct 18 16:13:48 2017 BST.