Molecular Science

Molecular Science

What is Chemistry? Nearly everything that is important to us gains its properties from the fact that it is made of molecules. Chemistry is the central Molecular Science. It is about everything that has to do with molecules: making them, using their properties to engineer useful things, studying fundamental physics with molecules, and using their physical properties to achieve new effects. Molecular science is the confluence of chemistry, physics, engineering, molecular biology, geology, medicine, and materials science. Thus, staff in the School of Chemistry work on projects strongly tied to other disciplines in exciting areas such as plasmonics, molecular magnets, battery technology, 3D printing, malaria, and many others. The School of Chemistry is therefore perfectly placed to form coalitions with the other schools and colleges to go after the big questions in science.

Research groupings

Recent publications

Microwave−assisted synthesis: from a mononuclear {CoII} complex to {CoII9} solvomorphs

Collet, A. , Wilson, C. and Murrie, M. (2018) Microwave−assisted synthesis: from a mononuclear {CoII} complex to {CoII9} solvomorphs. Dalton Transactions , (doi:10.1039/C8DT04557G ) (Early Online Publication)

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Transparent-to-dark photo- and electrochromic gels

Gonzalez, L. , Liu, C., Dietrich, B. , Su, H., Sproules, S. , Cui, H., Honecker, D., Adams, D. J. and Draper, E. R. (2018) Transparent-to-dark photo- and electrochromic gels. Communications Chemistry , 1, 77. (doi:10.1038/s42004-018-0075-2 )

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Chemical and structural data of (1,2,3-triazol-4-yl)pyridine-containing coordination compounds

Conradie, J., Conradie, M.M., Tawfiq, K.M., Al-Jeboori, M.J., D'Silva, C., Coles, S.J., Wilson, C. and Potgieter, J.H. (2018) Chemical and structural data of (1,2,3-triazol-4-yl)pyridine-containing coordination compounds. Data In Brief , 20, pp. 1397-1408. (doi:10.1016/j.dib.2018.08.125 ) (PMID:30255118) (PMCID:PMC6148730)

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Synthesis of functionalized indolines and dihydrobenzofurans by iron and copper catalyzed aryl C-N and C-O bond formation

Henry, M. C. , Senn, H. M. and Sutherland, A. (2018) Synthesis of functionalized indolines and dihydrobenzofurans by iron and copper catalyzed aryl C-N and C-O bond formation. Journal of Organic Chemistry , (Accepted for Publication)

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α-conotoxin GI triazole-peptidomimetics: potent and stable blockers of a human acetylcholine receptor

Knuhtsen, A. , Whitmore, C., McWhinnie, F. S. , McDougall, L. , Whiting, R., Smith, B. O., Timperley, C. M., Green, A. C., Kinnear, K. I. and Jamieson, A. G. (2018) α-conotoxin GI triazole-peptidomimetics: potent and stable blockers of a human acetylcholine receptor. Chemical Science , (doi:10.1039/C8SC04198A ) (Early Online Publication)

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Post-synthetic fluorination of Scholl-coupled microporous polymers for increased CO2 uptake and selectivity

Alahmed, A., Briggs, M. E., Cooper, A. and Adams, D. J. (2018) Post-synthetic fluorination of Scholl-coupled microporous polymers for increased CO2 uptake and selectivity. Journal of Materials Chemistry A , (doi:10.1039/C8TA09359H ) (Early Online Publication)

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An investigation of the role acceptor side chains play in the processibility and efficiency of organic solar cells fabricated from small molecular donors featuring 3,4-ethylenedioxythiophene cores

Mica, N.A., Almahmoud, S.A.J. , Krishnan Jagadamma, L., Cooke, G. and Samuel, I.D.W. (2018) An investigation of the role acceptor side chains play in the processibility and efficiency of organic solar cells fabricated from small molecular donors featuring 3,4-ethylenedioxythiophene cores. RSC Advances , 2018(8), pp. 39231-39240. (doi:10.1039/C8RA07034B )

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Organic synthesis in a modular robotic system driven by a chemical programming language

Steiner, S. et al. (2018) Organic synthesis in a modular robotic system driven by a chemical programming language. Science , (doi:10.1126/science.aav2211 ) (Early Online Publication)

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Enabling single qubit addressability in a molecular semiconductor comprising gold-supported organic radicals

McGuire, J. , Miras, H. N. , Richards, E. and Sproules, S. (2019) Enabling single qubit addressability in a molecular semiconductor comprising gold-supported organic radicals. Chemical Science , (doi:10.1039/C8SC04500C ) (Early Online Publication)

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Design, synthesis and evaluation of a diazirine photoaffinity probe for ligand-based receptor capture targeting G protein-coupled receptors

Müskens, F. M. , Ward, R. J. , Herkt, D. , van de Langemheen, H. , Tobin, A. B. , Liskamp, R. M.J. and Milligan, G. (2018) Design, synthesis and evaluation of a diazirine photoaffinity probe for ligand-based receptor capture targeting G protein-coupled receptors. Molecular Pharmacology , (Accepted for Publication)

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Selective disruption of mitochondrial thiol redox state in cells and in vivo

Booty, L. M. et al. (2018) Selective disruption of mitochondrial thiol redox state in cells and in vivo. Cell Chemical Biology , (Accepted for Publication)

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Investigation of dioxygen activation by copper(ii)-iminate/aminate complexes.

Papanikolaou, M. G., Hadjithoma, S., Chatzikypraiou, D. S., Papaioannou, D., Drouza, C., Tsipis, A. C., Miras, H. N. , Keramidas, A. D. and Kabanos, T. A. (2018) Investigation of dioxygen activation by copper(ii)-iminate/aminate complexes. Dalton Transactions , 47(45), pp. 16242-16254. (doi:10.1039/c8dt03137a ) (PMID:30398256)

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Maintaining homogeneity during a sol-gel transition by an autocatalytic enzyme reaction

Panja, S. and Adams, D. J. (2018) Maintaining homogeneity during a sol-gel transition by an autocatalytic enzyme reaction. Chemical Communications , (Accepted for Publication)

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Mutagenic products are promoted in the nitrosation of tyramine

González-Jiménez, M. , Arenas-Valgañón, J., García-Santos, M. d. P., Calle, E. and Casado, J. (2017) Mutagenic products are promoted in the nitrosation of tyramine. Food Chemistry , 216, pp. 60-65. (doi:10.1016/j.foodchem.2016.08.006 ) (PMID:27596392)

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Interference by nitrous acid decomposition in the kinetic study of nitrosation reactions

Arenas-Valgañón, J., Gómez-Bombarelli, R., González-Pérez, M., González-Jiménez, M. , Calle, E. and Casado, J. (2014) Interference by nitrous acid decomposition in the kinetic study of nitrosation reactions. International Journal of Chemical Kinetics , 46(6), pp. 321-327. (doi:10.1002/kin.20843 )

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Comment on “Stabilization of low-valent iron(I) in a high-valent vanadium(V) oxide cluster”

Sproules, S. (2018) Comment on “Stabilization of low-valent iron(I) in a high-valent vanadium(V) oxide cluster”. Angewandte Chemie , (Accepted for Publication)

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Mitochondria as a therapeutic target for common pathologies

Murphy, M. P. and Hartley, R. C. (2018) Mitochondria as a therapeutic target for common pathologies. Nature Reviews Drug Discovery , (doi:10.1038/nrd.2018.174 ) (PMID:30393373) (Early Online Publication)

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Autonomous clothes manipulation using a hierarchical vision architecture

Sun, L. , Aragon-Camarasa, G. , Rogers, S. and Siebert, J. P. (2018) Autonomous clothes manipulation using a hierarchical vision architecture. IEEE Access , (doi:10.1109/ACCESS.2018.2883072 ) (Early Online Publication)

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Investigating the breakdown of the nerve agent simulant methyl paraoxon and chemical warfare agents GB and VX using nitrogen containing bases

Wilson, C., Cooper, N. J., Briggs, M. E., Cooper, A. I. and Adams, D. (2018) Investigating the breakdown of the nerve agent simulant methyl paraoxon and chemical warfare agents GB and VX using nitrogen containing bases. Organic and Biomolecular Chemistry , (Accepted for Publication)

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Low cost triazatruxene hole transporting material for >20% efficient perovskite solar cells

Connell, A. et al. (2018) Low cost triazatruxene hole transporting material for >20% efficient perovskite solar cells. Journal of Materials Chemistry C , (doi:10.1039/C8TC04231D ) (Early Online Publication)

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