Dr Emma Sandilands
- Molecular Imaging Research Lab Manager / Technical Specialist (Therapeutic Science Research)
 
                        telephone: 
                        01413303974
                        email: 
                        Emma.Sandilands@glasgow.ac.uk
                    
Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, G61 1BD
Publications
2023
Nikolatou, K. et al. (2023) PTEN deficiency exposes a requirement for an ARF GTPase module for integrin-dependent invasion in ovarian cancer. EMBO Journal, 42, e1139. (doi: 10.15252/embj.2023113987) (PMID:37577760) (PMCID:PMC10505920)
    
    Nikolatou, Konstantina ORCID: https://orcid.org/0000-0002-5626-3390, Bryant, David M. 
ORCID: https://orcid.org/0000-0003-2721-5012 and Sandilands, Emma
  
(2023)
  
The ARF GTPase regulatory network in collective invasion and metastasis.
    
    Biochemical Society Transactions, 51(4),
	  pp. 1559-1569.
     
    
    (doi: 10.1042/BST20221355)
    (PMID:37622523) 
    (PMCID:PMC10586773) 
  
  
Sandilands, E. et al. (2023) The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. Journal of Cell Biology, 222(4), e202206115. (doi: 10.1083/jcb.202206115) (PMID:36880595) (PMCID:PMC9997661)
2022
Román-Fernández, A. et al. (2022) Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science Advances, 9(5), eabq1858. (doi: 10.1126/sciadv.abq1858) (PMID:36735782) (PMCID:PMC9897673)
Freckmann, E. C. et al. (2022) Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging. Nature Communications, 13, 5317. (doi: 10.1038/s41467-022-32958-x) (PMID:36085324) (PMCID:PMC9463449)
    
    Roman Fernandez, Alvaro ORCID: https://orcid.org/0000-0002-5032-3460, Sandilands, Emma and Bryant, David M. 
ORCID: https://orcid.org/0000-0003-2721-5012
  
(2022)
  
The use of three-dimensional cell culture to study apicobasal polarization and lumen formation.
    
    
      In: Chang, Chenbei and Wang, Jianbo (eds.)
      Cell Polarity Signaling.
    
    
      Series: Methods in Molecular Biology (2438).
    
    Springer, pp. 439-454.
         ISBN 9781071620342
        (doi: 10.1007/978-1-0716-2035-9_25)
  
  
2021
Nászai, M. et al. (2021) RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis. eLife, 10, e63807. (doi: 10.7554/eLife.63807) (PMID:34096503) (PMCID:PMC8216719)
Nacke, M. et al. (2021) An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism. Nature Communications, 12, 1623. (doi: 10.1038/s41467-021-21847-4) (PMID:33712589) (PMCID:PMC7955138)
2020
    
    Millar, Rhona, Kilbey, Anna, Remak, Sarah-Jane, Severson, Tesa M., Dhayade, Sandeep, Sandilands, Emma, Foster, Kyla, Bryant, David M. ORCID: https://orcid.org/0000-0003-2721-5012, Blyth, Karen 
ORCID: https://orcid.org/0000-0002-9304-439X and Coffelt, Seth B. 
ORCID: https://orcid.org/0000-0003-2257-2862
  
(2020)
  
The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer.
    
    Molecular Oncology, 14(8),
	  pp. 1868-1880.
     
    
    (doi: 10.1002/1878-0261.12734)
    (PMID:32484599) 
    (PMCID:PMC7400785) 
  
  
2018
    
    Román-Fernández, Álvaro ORCID: https://orcid.org/0000-0002-5032-3460, Roignot, Julie, Sandilands, Emma, Nacke, Marisa, Mansour, Mohammed A., McGarry, Lynn, Shanks, Emma, Mostov, Keith E. and Bryant, David M. 
ORCID: https://orcid.org/0000-0003-2721-5012
  
(2018)
  
The phospholipid PI(3,4)P2 is an apical identity determinant.
    
    Nature Communications, 9,
	 
      5041.
    
    (doi: 10.1038/s41467-018-07464-8)
    (PMID:30487552) 
    (PMCID:PMC6262019) 
  
  
    
    Hewit, Kay, Sandilands, Emma, Sanchez Martinez, Rafael, James, Daniel, Leung, Hing Y. ORCID: https://orcid.org/0000-0002-3933-3975, Bryant, David M. 
ORCID: https://orcid.org/0000-0003-2721-5012, Shanks, Emma and Markert, Elke K.
  
(2018)
  
A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor.
    
    Cell Death and Disease, 9(11),
	 
      1069.
    
    (doi: 10.1038/s41419-018-1115-7)
    (PMID:30341281) 
    (PMCID:PMC6195526) 
  
  
2017
    
    Datta, Anirban, Sandilands, Emma, Mostov, Keith E. and Bryant, David M. ORCID: https://orcid.org/0000-0003-2721-5012
  
(2017)
  
Fibroblast-derived HGF drives acinar lung cancer cell polarization through integrin-dependent RhoA-ROCK1 inhibition.
    
    Cellular Signalling, 40,
	  pp. 91-98.
     
    
    (doi: 10.1016/j.cellsig.2017.09.001)
    (PMID:28888686) 
     
  
  
    
    Schoenherr, Christina, Byron, Adam, Sandilands, Emma, Paliashvili, Ketevan, Baillie, George S. ORCID: https://orcid.org/0000-0003-2469-6316, Valacca, Cristina, Cecconi, Francesco, Serrels, Bryan and Frame, Margaret C.
  
(2017)
  
Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks.
    
    eLife, 6,
	 
      e23172.
    
    (doi: 10.7554/eLife.23172)
    (PMID:28362576) 
     
  
  
2015
Kanellos, G. et al. (2015) ADF and Cofilin1 control actin stress fibers, nuclear integrity, and cell survival. Cell Reports, 13(9), pp. 1949-1964. (doi: 10.1016/j.celrep.2015.10.056) (PMID:26655907) (PMCID:PMC4678118)
Articles
Nikolatou, K. et al. (2023) PTEN deficiency exposes a requirement for an ARF GTPase module for integrin-dependent invasion in ovarian cancer. EMBO Journal, 42, e1139. (doi: 10.15252/embj.2023113987) (PMID:37577760) (PMCID:PMC10505920)
    
    Nikolatou, Konstantina ORCID: https://orcid.org/0000-0002-5626-3390, Bryant, David M. 
ORCID: https://orcid.org/0000-0003-2721-5012 and Sandilands, Emma
  
(2023)
  
The ARF GTPase regulatory network in collective invasion and metastasis.
    
    Biochemical Society Transactions, 51(4),
	  pp. 1559-1569.
     
    
    (doi: 10.1042/BST20221355)
    (PMID:37622523) 
    (PMCID:PMC10586773) 
  
  
Sandilands, E. et al. (2023) The small GTPase ARF3 controls invasion modality and metastasis by regulating N-cadherin levels. Journal of Cell Biology, 222(4), e202206115. (doi: 10.1083/jcb.202206115) (PMID:36880595) (PMCID:PMC9997661)
Román-Fernández, A. et al. (2022) Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science Advances, 9(5), eabq1858. (doi: 10.1126/sciadv.abq1858) (PMID:36735782) (PMCID:PMC9897673)
Freckmann, E. C. et al. (2022) Traject3d allows label-free identification of distinct co-occurring phenotypes within 3D culture by live imaging. Nature Communications, 13, 5317. (doi: 10.1038/s41467-022-32958-x) (PMID:36085324) (PMCID:PMC9463449)
Nászai, M. et al. (2021) RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis. eLife, 10, e63807. (doi: 10.7554/eLife.63807) (PMID:34096503) (PMCID:PMC8216719)
Nacke, M. et al. (2021) An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism. Nature Communications, 12, 1623. (doi: 10.1038/s41467-021-21847-4) (PMID:33712589) (PMCID:PMC7955138)
    
    Millar, Rhona, Kilbey, Anna, Remak, Sarah-Jane, Severson, Tesa M., Dhayade, Sandeep, Sandilands, Emma, Foster, Kyla, Bryant, David M. ORCID: https://orcid.org/0000-0003-2721-5012, Blyth, Karen 
ORCID: https://orcid.org/0000-0002-9304-439X and Coffelt, Seth B. 
ORCID: https://orcid.org/0000-0003-2257-2862
  
(2020)
  
The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer.
    
    Molecular Oncology, 14(8),
	  pp. 1868-1880.
     
    
    (doi: 10.1002/1878-0261.12734)
    (PMID:32484599) 
    (PMCID:PMC7400785) 
  
  
    
    Román-Fernández, Álvaro ORCID: https://orcid.org/0000-0002-5032-3460, Roignot, Julie, Sandilands, Emma, Nacke, Marisa, Mansour, Mohammed A., McGarry, Lynn, Shanks, Emma, Mostov, Keith E. and Bryant, David M. 
ORCID: https://orcid.org/0000-0003-2721-5012
  
(2018)
  
The phospholipid PI(3,4)P2 is an apical identity determinant.
    
    Nature Communications, 9,
	 
      5041.
    
    (doi: 10.1038/s41467-018-07464-8)
    (PMID:30487552) 
    (PMCID:PMC6262019) 
  
  
    
    Hewit, Kay, Sandilands, Emma, Sanchez Martinez, Rafael, James, Daniel, Leung, Hing Y. ORCID: https://orcid.org/0000-0002-3933-3975, Bryant, David M. 
ORCID: https://orcid.org/0000-0003-2721-5012, Shanks, Emma and Markert, Elke K.
  
(2018)
  
A functional genomics screen reveals a strong synergistic effect between docetaxel and the mitotic gene DLGAP5 that is mediated by the androgen receptor.
    
    Cell Death and Disease, 9(11),
	 
      1069.
    
    (doi: 10.1038/s41419-018-1115-7)
    (PMID:30341281) 
    (PMCID:PMC6195526) 
  
  
    
    Datta, Anirban, Sandilands, Emma, Mostov, Keith E. and Bryant, David M. ORCID: https://orcid.org/0000-0003-2721-5012
  
(2017)
  
Fibroblast-derived HGF drives acinar lung cancer cell polarization through integrin-dependent RhoA-ROCK1 inhibition.
    
    Cellular Signalling, 40,
	  pp. 91-98.
     
    
    (doi: 10.1016/j.cellsig.2017.09.001)
    (PMID:28888686) 
     
  
  
    
    Schoenherr, Christina, Byron, Adam, Sandilands, Emma, Paliashvili, Ketevan, Baillie, George S. ORCID: https://orcid.org/0000-0003-2469-6316, Valacca, Cristina, Cecconi, Francesco, Serrels, Bryan and Frame, Margaret C.
  
(2017)
  
Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks.
    
    eLife, 6,
	 
      e23172.
    
    (doi: 10.7554/eLife.23172)
    (PMID:28362576) 
     
  
  
Kanellos, G. et al. (2015) ADF and Cofilin1 control actin stress fibers, nuclear integrity, and cell survival. Cell Reports, 13(9), pp. 1949-1964. (doi: 10.1016/j.celrep.2015.10.056) (PMID:26655907) (PMCID:PMC4678118)
Book Sections
    
    Roman Fernandez, Alvaro ORCID: https://orcid.org/0000-0002-5032-3460, Sandilands, Emma and Bryant, David M. 
ORCID: https://orcid.org/0000-0003-2721-5012
  
(2022)
  
The use of three-dimensional cell culture to study apicobasal polarization and lumen formation.
    
    
      In: Chang, Chenbei and Wang, Jianbo (eds.)
      Cell Polarity Signaling.
    
    
      Series: Methods in Molecular Biology (2438).
    
    Springer, pp. 439-454.
         ISBN 9781071620342
        (doi: 10.1007/978-1-0716-2035-9_25)
  
  
Research datasets
2021
Nászai, M., Bellec, K. , Yu, Y., Román-Fernández, Á., Sandilands, E., Johansson, J., Campbell, A., Norman, J. , Sansom, O. , Bryant, D. and Cordero, J. (2021) RAL GTPases mediate EGFR-driven intestinal stem cell hyperproliferation and tumourigenesis. [Data Collection]