2025

Herbert, Katharine J. ORCID: https://orcid.org/0000-0001-9437-0253, Upstill-Goddard, Rosie, Dreyer, Stephan B., Rebus, Selma, Pilarsky, Christian, Debabrata, Mukhopadhyay, Lord, Christopher J., Biankin, Andrew V. ORCID: https://orcid.org/0000-0002-0362-5597, Froeling, Fieke E.M. ORCID: https://orcid.org/0000-0002-8653-8164 and Chang, David K. ORCID: https://orcid.org/0000-0002-4821-3078 (2025) Sequential ATR and PARP inhibition overcomes acquired DNA damaging agent resistance in pancreatic ductal adenocarcinoma. British Journal of Cancer, (doi: 10.1038/s41416-025-03051-z) (Early Online Publication)

2024

Cooke, S. F. et al. (2024) Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC. Scientific Reports, 14, 8998. (doi: 10.1038/s41598-024-59451-3) (PMID:38637546) (PMCID:PMC11026450)

Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)

2022

Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)

Patel, M. et al. (2022) Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. British Journal of Cancer, 126(12), pp. 1704-1714. (doi: 10.1038/s41416-022-01729-2) (PMID:35173303) (PMCID:PMC9174220)

2021

Dreyer, S. B. et al. (2021) Targeting DNA damage response and replication stress in pancreatic cancer. Gastroenterology, 160(1), pp. 362-377. (doi: 10.1053/j.gastro.2020.09.043) (PMID:33039466) (PMCID:PMC8167930)

Articles

Herbert, Katharine J. ORCID: https://orcid.org/0000-0001-9437-0253, Upstill-Goddard, Rosie, Dreyer, Stephan B., Rebus, Selma, Pilarsky, Christian, Debabrata, Mukhopadhyay, Lord, Christopher J., Biankin, Andrew V. ORCID: https://orcid.org/0000-0002-0362-5597, Froeling, Fieke E.M. ORCID: https://orcid.org/0000-0002-8653-8164 and Chang, David K. ORCID: https://orcid.org/0000-0002-4821-3078 (2025) Sequential ATR and PARP inhibition overcomes acquired DNA damaging agent resistance in pancreatic ductal adenocarcinoma. British Journal of Cancer, (doi: 10.1038/s41416-025-03051-z) (Early Online Publication)

Cooke, S. F. et al. (2024) Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC. Scientific Reports, 14, 8998. (doi: 10.1038/s41598-024-59451-3) (PMID:38637546) (PMCID:PMC11026450)

Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)

Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)

Patel, M. et al. (2022) Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. British Journal of Cancer, 126(12), pp. 1704-1714. (doi: 10.1038/s41416-022-01729-2) (PMID:35173303) (PMCID:PMC9174220)

Dreyer, S. B. et al. (2021) Targeting DNA damage response and replication stress in pancreatic cancer. Gastroenterology, 160(1), pp. 362-377. (doi: 10.1053/j.gastro.2020.09.043) (PMID:33039466) (PMCID:PMC8167930)