Dr Kirsteen Campbell
- Honorary Senior Lecturer, Affiliate (School of Cancer Sciences)
email:
Kirsteen.Campbell@glasgow.ac.uk
CRUK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, G61 1BD
Publications
2023
Román-Fernández, A. et al. (2023) Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science Advances, 9(5), eabq1858. (doi: 10.1126/sciadv.abq1858) (PMID:36735782) (PMCID:PMC9897673)
Khan, A. S., Campbell, K. J., Cameron, E. R. and Blyth, K. (2023) The RUNX/CBFβ complex in breast cancer: a conundrum of context. Cells, 12(4), 641. (doi: 10.3390/cells12040641) (PMID:36831308) (PMCID:PMC9953914)
2022
Cao, K. et al. (2022) Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage. Developmental Cell, 57(10), 1211-1225.e6. (doi: 10.1016/j.devcel.2022.03.019) (PMID:35447090) (PMCID:PMC9616799)
2021
Bock, F. J. et al. (2021) Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature Communications, 12, 6572. (doi: 10.1038/s41467-021-26613-0) (PMID:34772930) (PMCID:PMC8590049)
Campbell, K. J. et al. (2021) Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function. Cell Death and Differentiation, 28(9), pp. 2589-2600. (doi: 10.1038/s41418-021-00773-4) (PMID:33785871) (PMCID:PMC8408186)
2020
Rooney, N. et al. (2020) RUNX1 is a driver of renal cell carcinoma correlating with clinical outcome. Cancer Research, 80(11), pp. 2325-2339. (doi: 10.1158/0008-5472.CAN-19-3870) (PMID:32156779)
Campbell, K. J. and Blyth, K. (2020) Somatic base editing to model oncogenic drivers in breast cancer. Lab Animal, 49, pp. 115-116. (doi: 10.1038/s41684-020-0510-8) (PMID:32152514)
Loveridge, C. J. et al. (2020) BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene, 39, pp. 1797-1806. (doi: 10.1038/s41388-019-1106-x) (PMID:31740786) (PMCID:PMC7033044)
2019
Liko, D. et al. (2019) Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas. Cell Death and Differentiation, 26(12), pp. 2535-2550. (doi: 10.1038/s41418-019-0316-7) (PMID:30858608) (PMCID:PMC6861133)
2018
Campbell, K. J. and Tait, S. W.J. (2018) Targeting BCL-2 regulated apoptosis in cancer. Open Biology, 8(5), 180002. (doi: 10.1098/rsob.180002) (PMID:29769323) (PMCID:PMC5990650)
Campbell, K. J. et al. (2018) MCL-1 is a prognostic indicator and drug target in breast cancer. Cell Death and Disease, 9, 19. (doi: 10.1038/s41419-017-0035-2) (PMID:29339815) (PMCID:PMC5833338)
2017
Campbell, K. J., Vandenberg, C. J., Anstee, N. S., Hurlin, P. J. and Cory, S. (2017) Mnt modulates Myc-driven lymphomagenesis. Cell Death and Differentiation, 24(12), pp. 2117-2126. (doi: 10.1038/cdd.2017.131) (PMID:28800127) (PMCID:PMC5686348)
Maddocks, O. D.K. et al. (2017) Modulating the therapeutic response of tumours to dietary serine and glycine starvation. Nature, 544(7650), pp. 372-376. (doi: 10.1038/nature22056) (PMID:28425994)
Anstee, N. S., Vandenberg, C. J., Campbell, K. J., Hughes, P. D., O’Reilly, L. A. and Cory, S. (2017) Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice. Cell Death and Differentiation, 24(3), pp. 397-408. (doi: 10.1038/cdd.2016.125) (PMID:27813531) (PMCID:PMC5344201)
2016
Woodward, J. et al. (2016) Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability. Genes and Development, 30(19), pp. 2173-2186. (doi: 10.1101/gad.284562.116) (PMID:27737961)
Birch, J. et al. (2016) The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma. Biology Open, 5(10), pp. 1371-1379. (doi: 10.1242/bio.019075) (PMID:27543055) (PMCID:PMC5087684)
Hunter, J.E., Butterworth, J.A., Zhao, B., Sellier, H., Campbell, K.J., Thomas, H.D., Bacon, C.M., Cockell, S.J., Gewurz, B.E. and Perkins, N.D. (2016) The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene, 35(26), pp. 3476-3484. (doi: 10.1038/onc.2015.399) (PMID:26522720) (PMCID:PMC4853301)
Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)
2015
Moniz, S., Bandarra, D., Biddlestone, J., Campbell, K.J., Komander, D., Bremm, A. and Rocha, S. (2015) Cezanne regulates E2F1-dependent HIF2 expression. Journal of Cell Science, 128(16), pp. 3082-3093. (doi: 10.1242/jcs.168864) (PMID:26148512) (PMCID:PMC4541044)
2014
Campbell, K. J. and White, R. J. (2014) MYC regulation of cell growth through control of transcription by RNA polymerases I and III. Cold Spring Harbor Perspectives in Medicine, 4(5), a018408-a018408. (doi: 10.1101/cshperspect.a018408)
Articles
Román-Fernández, A. et al. (2023) Spatial regulation of the glycocalyx component podocalyxin is a switch for prometastatic function. Science Advances, 9(5), eabq1858. (doi: 10.1126/sciadv.abq1858) (PMID:36735782) (PMCID:PMC9897673)
Khan, A. S., Campbell, K. J., Cameron, E. R. and Blyth, K. (2023) The RUNX/CBFβ complex in breast cancer: a conundrum of context. Cells, 12(4), 641. (doi: 10.3390/cells12040641) (PMID:36831308) (PMCID:PMC9953914)
Cao, K. et al. (2022) Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage. Developmental Cell, 57(10), 1211-1225.e6. (doi: 10.1016/j.devcel.2022.03.019) (PMID:35447090) (PMCID:PMC9616799)
Bock, F. J. et al. (2021) Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death. Nature Communications, 12, 6572. (doi: 10.1038/s41467-021-26613-0) (PMID:34772930) (PMCID:PMC8590049)
Campbell, K. J. et al. (2021) Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function. Cell Death and Differentiation, 28(9), pp. 2589-2600. (doi: 10.1038/s41418-021-00773-4) (PMID:33785871) (PMCID:PMC8408186)
Rooney, N. et al. (2020) RUNX1 is a driver of renal cell carcinoma correlating with clinical outcome. Cancer Research, 80(11), pp. 2325-2339. (doi: 10.1158/0008-5472.CAN-19-3870) (PMID:32156779)
Campbell, K. J. and Blyth, K. (2020) Somatic base editing to model oncogenic drivers in breast cancer. Lab Animal, 49, pp. 115-116. (doi: 10.1038/s41684-020-0510-8) (PMID:32152514)
Loveridge, C. J. et al. (2020) BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene, 39, pp. 1797-1806. (doi: 10.1038/s41388-019-1106-x) (PMID:31740786) (PMCID:PMC7033044)
Liko, D. et al. (2019) Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas. Cell Death and Differentiation, 26(12), pp. 2535-2550. (doi: 10.1038/s41418-019-0316-7) (PMID:30858608) (PMCID:PMC6861133)
Campbell, K. J. and Tait, S. W.J. (2018) Targeting BCL-2 regulated apoptosis in cancer. Open Biology, 8(5), 180002. (doi: 10.1098/rsob.180002) (PMID:29769323) (PMCID:PMC5990650)
Campbell, K. J. et al. (2018) MCL-1 is a prognostic indicator and drug target in breast cancer. Cell Death and Disease, 9, 19. (doi: 10.1038/s41419-017-0035-2) (PMID:29339815) (PMCID:PMC5833338)
Campbell, K. J., Vandenberg, C. J., Anstee, N. S., Hurlin, P. J. and Cory, S. (2017) Mnt modulates Myc-driven lymphomagenesis. Cell Death and Differentiation, 24(12), pp. 2117-2126. (doi: 10.1038/cdd.2017.131) (PMID:28800127) (PMCID:PMC5686348)
Maddocks, O. D.K. et al. (2017) Modulating the therapeutic response of tumours to dietary serine and glycine starvation. Nature, 544(7650), pp. 372-376. (doi: 10.1038/nature22056) (PMID:28425994)
Anstee, N. S., Vandenberg, C. J., Campbell, K. J., Hughes, P. D., O’Reilly, L. A. and Cory, S. (2017) Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice. Cell Death and Differentiation, 24(3), pp. 397-408. (doi: 10.1038/cdd.2016.125) (PMID:27813531) (PMCID:PMC5344201)
Woodward, J. et al. (2016) Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability. Genes and Development, 30(19), pp. 2173-2186. (doi: 10.1101/gad.284562.116) (PMID:27737961)
Birch, J. et al. (2016) The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma. Biology Open, 5(10), pp. 1371-1379. (doi: 10.1242/bio.019075) (PMID:27543055) (PMCID:PMC5087684)
Hunter, J.E., Butterworth, J.A., Zhao, B., Sellier, H., Campbell, K.J., Thomas, H.D., Bacon, C.M., Cockell, S.J., Gewurz, B.E. and Perkins, N.D. (2016) The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene, 35(26), pp. 3476-3484. (doi: 10.1038/onc.2015.399) (PMID:26522720) (PMCID:PMC4853301)
Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi: 10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)
Moniz, S., Bandarra, D., Biddlestone, J., Campbell, K.J., Komander, D., Bremm, A. and Rocha, S. (2015) Cezanne regulates E2F1-dependent HIF2 expression. Journal of Cell Science, 128(16), pp. 3082-3093. (doi: 10.1242/jcs.168864) (PMID:26148512) (PMCID:PMC4541044)
Campbell, K. J. and White, R. J. (2014) MYC regulation of cell growth through control of transcription by RNA polymerases I and III. Cold Spring Harbor Perspectives in Medicine, 4(5), a018408-a018408. (doi: 10.1101/cshperspect.a018408)
Research datasets
2018
Maddocks, O. , Athineos, D., Cheung, E. C., Lee, P., Zhang, T., van den Broek, N. J.F., Mackay, G., Labuschagne, C. F., Gay, D., Kruiswijk, F., Blagih, J., Vincent, D., Campbell, K., Ceteci, F., Sansom, O. , Blyth, K. and Vousden, K. (2018) Modulating the therapeutic response of tumours to dietary serine and glycine starvation. [Data Collection]