Professor Barbara Mable
- Professor of Evolutionary Genetics, Director of Education (Evolution & Diversity) (Evolution & Diversity)
telephone:
3532
email:
Barbara.Mable@glasgow.ac.uk
R404 Level 4, Institute of BAH&CM, Graham Kerr Building, Glasgow G12 8QQ
Research interests
Evolutionary genetics of mating systems in plants.
Evolutionary consequences of polyploidy in plants and animals.
Conservation genetics of plants, amphibians, fish and mammals
Host-vector-pathogen dynamics
Evolution of resistance in pests and parasites
Research Interests - further information
Google Scholar - Publications Profile
Research groups
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- SpudCows: Can potatoes provide a valuable nutritional supplement for ruminants?
Scottish Funding Council
2025 - 2025
- Population dynamics and feeding ecology analysis of samples from the 2023 long finned pilot whale mass stranding event
JNCC UK
2024 - 2025
- How do free-living nematodes (FLN) interact with the microbial populations in soil?
Wellcome Trust
2021 - 2023
- A Decision Support tool for Potato Blackleg Disease (DeS-BL)
Biotechnology and Biological Sciences Research Council
2020 - 2023
- What can you learn from a fly? Biting insects as noninvasive samplers
Leverhulme Trust
2020 - 2023
- United States-UK partnering award:Co-infection and resistance (CORE)
Biotechnology and Biological Sciences Research Council
2016 - 2020
- The BUG consortium Building Upon the Genome: using H. contortus genomic resources to develop novel interventions to control endemic GI parasites
Biotechnology and Biological Sciences Research Council
2015 - 2020
- Omics of adaption to changing/novel environments in plants (ISSF STS)
Wellcome Trust
2014 - 2014
- Assessing the impact of plant mating system and ploidy on adaptation to parasitism in changing environments
Natural Environment Research Council
2011 - 2014
- Development of best practice model Doctoral Schools for structured PhD programme implementation in Ukraine and Georgia (Asp2PhD).
European Commission
2010 - 2013
- How colonisation, mating system and selection impact genetic diversity in Arabidopsis lyrata
Biotechnology and Biological Sciences Research Council
2010 - 2010
- Genetic basis of parasite resistance in a feral population of Xenopus.
Natural Environment Research Council
2010 - 2011
- Stress memory and its relation to stress tolerance in plants
Leverhulme Trust
2009 - 2012
- Leveraging the genome sequences of two arabidopsis relatives for evolutionary and ecological genomics
Biotechnology and Biological Sciences Research Council
2007 - 2010
- Mating systems and genetic diversity in Arabidopsis lyrata
Natural Environment Research Council
2007 - 2010
- Establishment of outcrossing rates in natural populations of Arabidopsis lyrata
Natural Environment Research Council
2006 - 2006
- Mitochondrial gene sequence of eiders as a means of defining subspecies
Joint Nature Conservation Committee
2005 - 2006
- Sexing of seabirds
NERC Centre for Ecology and Hydrology
2005 - 2006
- Genomes, pathogens and mate choice - implications for the evolution and maintenance of genetic diversity
Natural Environment Research Council
2004 - 2009
Supervision
- Liang, Jing
Novel insights into tick-borne disease ecology through host blood meal identification - Munisi, Kelvin Japhet
Genomic Approaches to Understanding Connectivity, Genetic Viability, and Population Dynamics in Cheetahs (Acinonyx jubatus) across the Eastern Africa landscape. - Paez Triana, Luisa Fernanda
Characterizing the relationship between vertebrate diversity, abundance and pathogen dynamics among restored woodlands over a spatiotemporal gradient - Sullivan, Connor
Host-pathogen-environment dynamics of the amphibian chytrid fungi.
Professional activities & recognition
Prizes, awards & distinctions
- 2003: Presidential Distinguished Professor Award, (University of Guelph)
Research fellowships
- 2004 - 2009: Natural Environment Advanced Research Fellowship
- 2004 - 2006: Marie Curie Incoming International Fellowship, University of Glasgow (declined)
- 2000 - 2005: Natural Sciences and Engineering Council University Faculty Award, University of Guelph, Canada
- 1996 - 1998: Izaak Walton Killam Memorial Fellowship, University of British Columbia
Grant committees & research advisory boards
- 2018: UKRI, Future Leaders Fellowships (5 rounds of sift and 6 rounds of interview panels 2018-2022; Chaired 7 panels)
- 2013 - 2016: NERC, Core Panel Member
- 2012 - 2013: NERC, Member of Peer Review College
- 2010 - 2012: LABEX Jury, France, Panel to review applications for centres of excellence
- 2007 - 2017: University of Oslo, Norway, Scientific Advisory Board for the Centre of Excellence for Ecological and Evolutionary Synthesis
- 2006 - 2010: NERC, Molecular Genetics/ Biomolecular Analysis Facility Steering Committee
- 2006 - 2009: NERC, Member of Peer Review College
Editorial boards
- 2016 - 2022: Heredity. Editor-in-Chief
- 2013 - 2016: Axios. Subject Editor
- 2012 - 2013: Heredity. Guest Editor, special issue on "Hybridisation, invasion and adaptation, the evolutionary dynamics of polyploidy in changing environments"; Heredity 110 (2)
- 2011 - 2016: Heredity. Subject Editor
- 2007 - 2008: Genetics Research. Guest Editor with Bill Hill, special issue in celebration of Deborah Charlesworth's retirement; Genetics research 90 (1)
Professional & learned societies
- 2018: Vice President, Glasgow Natural History Society
- 2017: Chair, Blodwen LLoyd Binns Trust
- 2017: Member, British Society for Plant Pathology
- 2016 - 2022: Executive, Genetics Society
- 2011 - 2012: President, Glasgow Natural History Society
- 2011: Member, British Ecological Society
- 2012 - 2017: Council Member, Glagsow Natural History Society
- 2005: Member, Genetics Society
- 2005 - 2008: Finance Committee Member, European Society for Evolutionary Biology
- 2001: Member, European Society for Evolutionary Biology
- 2001: Member, Society for the Study of Evolution
- 2001 - 2009: Member, Genetics Society of America
Selected international presentations
- 2013: Conference Organiser, Population Genetics Group 46 (184 delegates) (Glasgow, Scotland, UK)
- 2012: Invited speaker, workshop on Ecological and Evolutionary Genomics of Plant Adaptation (Aberdeen, Scotland, UK)
- 2011: Invited speaker, Harvard Plant Biology symposium, “Genetics of Adaptation” (Cambridge, Massachusetts)
- 2010: Distinguished guest speaker, Centre for Ecological and Evolutionary Synthesis, University of Oslo, Colloquium “Bridging the gap between genomics and evolutionary biology” (Oslo, Norway)
- 2010: Invited participant, Brassica Map Alignment Project Workshop (Tübingen, Germany)
- 2009: Invited Speaker, "Darwin and Evolution Today Event" (Glasgow, Scotland, UK)
- 2008: Invited keynote speaker, Linnaean Society: "The New Evolution” (London, UK)
- 2008: Invited speaker, Phylogenomics workshop at Brassica 2008 (Lillehammer, Norway)
- 2007: Invited Speaker, The 5th International Okazaki Biology Conference: "Speciation and Adaptation. Ecological Genomics of Model Organisms and Beyond" (Japan)
- 2007: Invited speaker, International Conference on Polyploidy, heterosis and epigenetics (Beijing, China)
- 2005: Invited workshop participant, Arabidopsis lyrata research group, University of Leeds (Leeds, England, UK)
- 2004: Invited symposium speaker, Polyploidy Workshop at the Plant and Animal Genome XII Conference: "Inheritance and dominance of self-incompatibility alleles in polyploid Arabidopsis lyrata (Brassicaceae)" (San Diego, CA, USA)
- 2003: Invited speaker, International Polyploidy Conference: "Why polyploidy is rarer in animals than in plants revisited: Myths and Mechanisms", Linnean Society and Royal Botanical Gardens (Kew, England, UK)
- 2003: Invited speaker, 5th International Conference on Computational Biology and Genome Informatics: "Molecular Systematics: All phylogenies are not created equal" (Carey, North Carolina, USA)
- 2002: Invited speaker, University of Glasgow, "Evolutionary genetics of cell-cell recognition systems: gene duplication, polyploidy, and genetic diversity" (Glasgow, Scotland, UK)
- 2001: Plenary Speaker, Ontario Ethology and Ecology Colloquium: 'Molecular evolution and mate recognition systems: Plants can be interesting too", University of Guelph (Guelph, Ontaria, Canada)
- 2017: Invited Speaker, Fourth Research Coordination Meeting on Enhanced Vector Refractoriness to Trypanosome infection (Tanga, Tanzania)
- 2017: Inviteed speaker, Conservation of Adaptive Potential and Functional Diversity Workshop (Durham, UK)
- 2015: Invited speaker, Molecular Ecology and Evolution Conference (Vienna, Austria)
- 2017: Keynote speaker, Future Directions of Conservation Science Symposium (Chester, UK)
- 2015: Invited speaker, Royal Society Meeting: Elements, genomes and ecosystems (London, UK)
- 2015: Plenary speaker, Population Genetics Group (Sheffield, UK)
- 2014: Invited speaker, UK Plant Evolution Conference (Edinburgh, UK)
- 2013: Invited speaker, European Association of Zoos and Aquaria Conference (Edinburgh, UK)
Supplementary
- Invited Seminars (since 2014) • Linköping University, Sweden, May 6, 2021. “Conservation Genetics in the Deep Sequencing Era.” University of Sheffield, March 28, 2019. “Phyto-herpetology, phylo-population genetics, crop-livestock-wildlife management: growing up at the interface of disparate fields”, Invited as part of the Margaret Savigear annual lecture to feature inspiring women biologists. • University of Oxford, November 16, 2017. "Adding complexity to complexity: gene family evolution in polyploids”. • University of Durham, January 26, 2016. “Evolutionary genetics in the ‘omics era: addressing old questions with new tools”. • University of Vienna, November 27, 2014, “Resolving the cause of mating system shifts in plants: an evolutionary detective story”. • Vienna Graduate School of Population Genetics, November 28, 2014, “Gene family evolution and the adaptive dynamics of natural populations” • University of Bath, December 3, 2014, “Plants, Pathogens and Parentage: Gene family evolution and the adaptive dynamics of natural populations”. External Examiner for PhD Vivas • Jörn Fredrick Gerchen, Faculty of Biology and Medicine, University of Lausanne, External Expert for PhD Defense, August 16, 2021 • Martha Gavan, School of Biological Sciences, University of Aberdeen, December, 2017 • Jing Wang, Umeå Plant Science Centre, University of Umeå, June, 2016 • Charlie Dove Ellis, Centre for Ecology and Conservation, University of Exeter, May, 2016. • Gonçalo Rosa, Durrell Institute of Conservation and Ecology, School of Anthropology and Conservation, University of Kent, October, 2015 • Sarah Marburger, Molecular Ecology and Fisheries Genetics Laboratory, School of Biological Science Bangor University, October, 2015 • Josh Koh, School of Botany, University of Melbourne, April 2013. • Oliver Pescott, Animal and Plant Sciences, University of Sheffield, April, 2013. • Amy Ellison, Institute of Biological, Environmental & Rural Sciences, Aberystwyth University, October, 2012. • Chloe Thompson, Centre for Plant Sciences, University of Leeds, December 17, 2010. • Melvin Smith, School of the Environment and Society, University of Swansea, March, 2009; re-examined February 2010. • Marc Stift, Institute for Biodiversity and Ecosystem Dynamics, University of Amsterdam, July, 2007. • Andreas Athanasiou, York University, Toronto, Canada, November, 2001
Research datasets
Research Overview
Research in my laboratory (the evolutionary genetics group) is directed towards understanding how changes at the molecular level affect cellular and whole organism processes in a wide range of organisms (Figure 1). Most of my early work focused on the genetic and ecological consequences of a particularly extreme form of genetic change- whole genome duplication or polyploidy- but I have also been interested in the consequences of gene duplication at the level of gene families that control recognition processes involved in adaptation, such as plant self-incompatibility systems (SI), plant resistance genes, and the vertebrate immune genes (e.g. the Major Histocompatibility Complex, MHC). I am particularly interested in how such genomic changes affect interactions between organisms, such as mate choice and pathogen responses. Some of my primary areas of interest have been: 1) the evolutionary dynamics of gene families involved in recognition systems; 2) the causes and consequences of changes in mating systems for genetic diversity and adaptation; and 3) the consequences of mating system variation and polyploidy for mate recognition and pathogen response.

Figure 1. Some research questions and study organisms: evolution of mating systems and polyploidy in a) grey treefrogs (Hyla versicolor) and b) rock cress (Arabidopsis lyrata); conservation genetics of c) black rhinoceros, d) Exmoor ponies and e) African wild dogs; f) evolution of resistance to anthelmintics in nematodes infecting livestock; g) host-pathogen-vector dynamics (e.g. multiple species of tsetse flies feed on a wide range of wild and domestic hosts and can transmit multiple species of trypanosomes); and h) the influence of soil microbial communities on control of bacterial pathogens of crops.
Although we work on a wide range of organisms (bacteria, fungi, oomycetes, plants, nematodes, trematodes, kinetoplastids, molluscs, insects, amphibians, fish, birds and mammals), a central theme is considering the relative importance of genetic variation in general: how critical is it for adaptation and can genetics be used effectively to inform management interventions for conservation and disease mitigation? This has also led to new funding opportunities that have enabled diversification of our evolutionary genetics research team (Figure 2).

Figure 2. Lockdown teamwork: remote meeting of the evolutionary genetics group.
Ongoing projects led by recent or current PhD students include: 1) assessing diversity of the rhizosphere of plants in the genus Brassica in relation to cultivars and population genetic structure (Elizabeth Mittell, PhD awarded in 2019, funded by a Lord Kelvin and Adam Smith Scholarship); 2) developing molecular markers to inform translocation strategies for fenced populations of Southern White Rhinoceros in Botswana (Tarid Purisotayo, PhD awarded in 2020, funded by the government of Thailand); 3) investigating the genetic and ecological drivers of resistance in parasitic nematodes of sheep (Sam Brown, PhD candidate, funded by NERC); 4) conservation genetics and rewilding of Exmoor ponies (Debbie Davy, PhD candidate, funded by the Exmoor Pony Society); 5) genomic selection for immune function in cattle (Kamonchanok [June] Chooyoung, PhD candidate, funded by the government of Thailand); 6) assessing levels of genetic variation in protected populations of Northern Black Rhinoceros across Tanzania (Ronald Vincent Mellya, PhD candidate, funded by Zurich Zoo); and 7) how climate change is affecting economically important fish in Nigeria (Mark Kauna Sanda, PhD candidate, funded by a Commonwealth scholarship).
In collaboration with Umer Zeeshan Ijaz, Tom Morrison, Grant Hopcraft at Glasgow, and Linus Munishi at the Nelson Mandela African Institute of Science and Technology, a recent project led by two former master’s students, Koggani Koggani (funded by a Karimjee Jivanjee Scholarship and the Rufford Foundation) and Rachel Gray, is to use deep sequencing of chloroplast DNA amplicons to compare the diets of endangered ungulates and encroaching cattle populations.
Two funded collaborative research projects are led by postdoctoral fellows (Anubhab Khan and Ciara Keating) and critically supported by research technicians (Elizabeth Kilbride and Ryan Carter): 1) “What can you learn from a fly? Biting insects as noninvasive samplers” (funded by the Leverhulme Trust), in collaboration with Harriet Auty (IBAHCM) and a former Phd student, Manun Channumsin; and 2) “A Decision Support tool for Potato Blackleg Disease (DeS-BL)” (funded by BBSRC, NERC, DEFRA and the Scottish government), a consortium grant in the Bacterial Plant Diseases Programme, led by the James Hutton Institute (Ian Toth PI), in collaboration with Umer Zeeshan Ijaz (School of Engineering) and Joel Milner (MCSB) at Glasgow; you can hear Ciara talk about the project here.
