Professor Paul Welsh
- Professor of Molecular Epidemiology (Cardiovascular & Metabolic Health)
telephone:
01413301722
email:
Paul.Welsh@glasgow.ac.uk
237 Level C2, BHF Glasgow Cardiovascular Research Centre, 126 University Place, Glasgow, G12 8TA
Biography
Paul completed a BSc (Hons) in Immunology as a University of Glasgow undergraduate and a PhD investigating the associations of inflammatory biomarkers with CVD under Prof Gordon Lowe at Glasgow Royal Infirmary. Working with Prof Naveed Sattar, Paul was awarded a BHF Advanced Training Fellowship in 2010 and a BHF Intermediate Basic Scientist Fellowship in 2013, focusing on use of natriuretic peptides and other biomarkers of cardiac stress in the general population. Paul was awarded a distinction and the 150th Anniversary prize during an MSc in Epidemiology at London School of Hygiene and Tropical Medicine in 2014. He was awarded a Readership in 2019 and a Chair in 2023.
Research interests
Research Theme: Metabolic Disease
Paul's research work encompasses a wide range of epidemiological work investigating risk factors for cardiovascular disease, diabetes and other related chronic and acute conditions.
In particular, Paul's work focuses on the use circulating biomarkers of health and disease to improve patient care. He leads the Glasgow Biomarker Research Unit (GlasBRU), and his team conduct a wide range of assays in blood urine and saliva samples including those performed in routine clinical biochemistry settings, and more specialised tests. He and his team have been involved in many seminal observational studies (such as British Regional Heart Study, Lothian Birth cohort, ALSPAC, and Generation Scotland) and clinical trials (such as DAPA-HF, DAPA-RESIST, DiRECT, STANDby, TARTAN-HF, T-TIME, CorMicA ,PRIZE, SUGAR-DM-HF and RECOVER-LV). They have access to a vast biobank of current and historical studies including WOSCOPS, PROSPER, and ADVANCE trials.
Biomarkers of special interest to Paul include cardiac biomarkers such as NT-proBNP and high sensitivity troponin. He has also been an active researcher in the UK Biobank resource.
Research groups
Publications
2024
Anderson, J. J., Deo, S. V. , Welsh, P. , Mackay, D. F. , Ho, F. K., Ferguson, L. D. , Celis-Morales, C. , Gill, J.R. , Pell, J. P. and Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949) (Early Online Publication)
Xiong, X. et al. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (Accepted for Publication)
Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901) (PMID:39217504) (Early Online Publication)
Liu, Q., Celis-Morales, C. , Sattar, N. and Welsh, P. (2024) Association of glycaemic control with intraocular pressure in a large general population: Results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865) (Early Online Publication)
Liu, Q., Celis-Morales, C. , Sattar, N. and Welsh, P. (2024) Association of glycemic control with intraocular pressure in a large general population: results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865) (PMID:39157858) (Early Online Publication)
Carberry, J. et al. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure, 11(4), pp. 2001-2012. (doi: 10.1002/ehf2.14830) (PMID:38715187) (PMCID:PMC11287338)
Churuangsuk, C., Catchpole, A., Talwar, D., Welsh, P. , Sattar, N. , Combet Aspray, E. and Lean, M. E.J. (2024) Low thiamine status in adults following low-carbohydrate / ketogenic diets: a cross-sectional comparative study of micronutrient intake and status. European Journal of Nutrition, (doi: 10.1007/s00394-024-03459-y) (PMID:38967675) (Early Online Publication)
Curtain, J. P. et al. (2024) Measuring congestion with a non-invasive monitoring device in heart failure and haemodialysis: CONGEST-HF. European Journal of Heart Failure, 26(6), pp. 1383-1392. (doi: 10.1002/ejhf.3290) (PMID:38741283)
Al-Abdullah, L., Ahern, A., Welsh, P. and Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, (Accepted for Publication)
Hillary, R. F. et al. (2024) Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts. Cell Genomics, 4(5), 100544. (doi: 10.1016/j.xgen.2024.100544) (PMID:38692281) (PMCID:PMC11099341)
Lean, M. E.J. et al. (2024) 5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study. Lancet Diabetes and Endocrinology, 12(4), pp. 233-246. (doi: 10.1016/S2213-8587(23)00385-6) (PMID:38423026)
Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, 32. (doi: 10.1038/s43856-024-00455-5) (PMID:38418616) (PMCID:PMC10901805)
Bull, C. J. et al. (2024) Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes. EBioMedicine, 100, 104977. (doi: 10.1016/j.ebiom.2024.104977) (PMID:38290287) (PMCID:PMC10844806)
Chybowska, A. D. et al. (2024) Epigenetic contributions to clinical risk prediction of cardiovascular disease. Circulation: Genomic and Precision Medicine, 17(1), e004265. (doi: 10.1161/CIRCGEN.123.004265) (PMID:38288591)
Welsh, P. et al. (2024) Elevated lipoprotein(a) increases risk of subsequent major adverse cardiovascular events (MACE) and coronary revascularisation in incident ASCVD patients: a cohort study from the UK biobank. Atherosclerosis, 389, 117437. (doi: 10.1016/j.atherosclerosis.2023.117437) (PMID:38219651)
Corbin, L. J. et al. (2024) The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT). Diabetologia, 67(1), pp. 74-87. (doi: 10.1007/s00125-023-06019-x) (PMID:37878066) (PMCID:PMC10709482)
Sofianopoulou, E. et al. (2024) Estimating dose—response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and revised Mendelian randomization analyses. Lancet Diabetes and Endocrinology, 12(1), E2-E11. (doi: 10.1016/S2213-8587(23)00287-5) (PMID:38048800)
2023
Welsh, P. et al. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study. Clinical Chemistry, 70(2), pp. 403-413. (doi: 10.1093/clinchem/hvad205) (PMID:38069915)
Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7(4), pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)
Goudswaard, L. J. et al. (2023) Using trials of caloric restriction and bariatric surgery to explore the effects of body mass index on the circulating proteome. Scientific Reports, 13, 21077. (doi: 10.1038/s41598-023-47030-x) (PMID:38030643) (PMCID:PMC10686974)
McDowell, K., Adamson, C., Jackson, C., Campbell, R., Welsh, P. , Petrie, M. C. , McMurray, J. J.V. , Jhund, P. and Herring, N. (2023) Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes. European Journal of Heart Failure, (doi: 10.1002/ejhf.3085) (PMID:37937329) (Early Online Publication)
Sattar, N. et al. (2023) Prediction of cardiometabolic health through changes in plasma proteins with intentional weight loss in the DiRECT and DIADEM-I randomised clinical trials of type 2 diabetes remission. Diabetes Care, 46(11), pp. 1949-1957. (doi: 10.2337/dc23-0602) (PMID:37756566) (PMCID:PMC10628468)
Al Ozairi, E. et al. (2023) The effect of home-based resistance exercise training in people with type 2 diabetes: a randomized controlled trial. Diabetes/Metabolism Research and Reviews, 39(7), e3677. (doi: 10.1002/dmrr.3677) (PMID:37330638)
Boonpor, J. et al. (2023) Associations and predictive performance of eleven anthropometric measures with incident type 2 diabetes: a prospective cohort study from the UK Biobank. Obesity, 31(10), pp. 2648-2657. (doi: 10.1002/oby.23849) (PMID:37724055)
Logan, G. , Somers, C., Baker, G., Connell, H., Gray, S. , Kelly, P., McIntosh, E. , Welsh, P. , Gray, C. and Gill, J. M. (2023) Benefits, risks, barriers, and facilitators to cycling: a narrative review. Frontiers in Sports and Active Living, 5, 1168357. (doi: 10.3389/fspor.2023.1168357) (PMID:37795314) (PMCID:PMC10546027)
Yeoh, S. E. et al. (2023) Dapagliflozin versus metolazone in heart failure resistant to loop diuretics. European Heart Journal, 44(31), pp. 2966-2977. (doi: 10.1093/eurheartj/ehad341) (PMID:37210742)
Karusheva, Y. et al. (2023) Association of GDF15 levels with body mass index and endocrine status in β-thalassaemia. Clinical Endocrinology, 99(2), pp. 182-189. (doi: 10.1111/cen.14897) (PMID:36806122)
Zhou, Z., Parra-Soto, S., Boonpor, J., Petermann-Rocha, F., Welsh, P. , Mark, P. B. , Sattar, N. , Pell, J. P. , Celis-Morales, C. and Ho, F. K. (2023) Exploring the underlying mechanisms linking adiposity and cardiovascular disease: a prospective cohort study of 404,332 UK Biobank participants. Current Problems in Cardiology, 48(8), 101715. (doi: 10.1016/j.cpcardiol.2023.101715) (PMID:37004891)
Docherty, K. F. et al. (2023) Association of carbohydrate antigen 125 on the response to dapagliflozin in patients with heart failure. Journal of the American College of Cardiology, 82(2), pp. 142-157. (doi: 10.1016/j.jacc.2023.05.011) (PMID:37407113)
Boonpor, J. et al. (2023) Association between walking pace and incident type 2 diabetes by adiposity levels – a prospective cohort study from the UK Biobank. Diabetes, Obesity and Metabolism, 25(7), pp. 1900-1910. (doi: 10.1111/dom.15053) (PMID:36951683)
Soltanisarvestani, M., Lynskey, N., Gray, S. , Gill, J. M.R. , Pell, J. P. , Sattar, N. , Welsh, P. , Ho, F. K., Celis-Morales, C. and Petermann-Rocha, F. (2023) Associations of grip strength and walking pace with mortality in stroke survivors: a prospective study from UK Biobank. Scandinavian Journal of Medicine and Science in Sports, 33(7), pp. 1190-1200. (doi: 10.1111/sms.14352) (PMID:36932055)
Yeoh, S. E. et al. (2023) Endothelin-1, outcomes in patients with heart failure and reduced ejection fraction, and effects of dapagliflozin: findings from DAPA-HF. Circulation, 147(22), pp. 1670-1683. (doi: 10.1161/CIRCULATIONAHA.122.063327) (PMID:37039015) (PMCID:PMC10212584)
Boonpor, J. et al. (2023) Dose–response relationship between device-measured physical activity and incident type 2 diabetes: findings from the UK Biobank prospective cohort study. BMC Medicine, 21, 191. (doi: 10.1186/s12916-023-02851-5) (PMID:37226202) (PMCID:PMC10210409)
Al-Sawaf, O. et al. (2023) Body composition and lung cancer-associated cachexia in TRACERx. Nature Medicine, 29(4), pp. 846-858. (doi: 10.1038/s41591-023-02232-8) (PMID:37045997) (PMCID:PMC7614477)
Mooney, L., Jackson, C. E., Adamson, C., McConnachie, A. , Welsh, P. , Myles, R. C. , McMurray, J. J.V. , Jhund, P. S. , Petrie, M. C. and Lang, N. N. (2023) Adverse outcomes associated with interleukin-6 in patients recently hospitalized for heart failure with preserved ejection fraction. Circulation: Heart Failure, 16(4), e010051. (doi: 10.1161/CIRCHEARTFAILURE.122.010051) (PMID:36896709) (PMCID:PMC10101136)
Adamson, C. et al. (2023) IGFBP-7 and outcomes in heart failure with reduced ejection fraction: findings from DAPA-HF. JACC: Heart Failure, 11(3), pp. 291-304. (doi: 10.1016/j.jchf.2022.09.004) (PMID:36592046)
Chu, W., Lynskey, N., Iain-Ross, J., Pell, J. P. , Sattar, N. , Ho, F. K., Welsh, P. , Celis-Morales, C. and Petermann-Rocha, F. (2023) Identifying the biomarker profile of pre-frail and frail people: a cross-sectional analysis from UK Biobank. International Journal of Environmental Research and Public Health, 20(3), 2421. (doi: 10.3390/ijerph20032421) (PMID:36767787) (PMCID:PMC9915970)
Chua, S. Y.L. et al. (2023) Associations between HbA1c across the normal range, diagnosed, and undiagnosed diabetes and retinal layer thickness in UK Biobank cohort. Translational Vision Science and Technology, 12(2), 25. (doi: 10.1167/tvst.12.2.25) (PMID:36795065) (PMCID:PMC9940769)
Sattar, N. , Welsh, P. , Leslie, W. S., Thom, G. , McCombie, L., Brosnahan, N. , Richardson, J. , Gill, J. M. R. , Crawford, L. and Lean, M. E. J. (2023) Dietary weight-management for type 2 diabetes remissions in South Asians: the South Asian diabetes remission randomised trial for proof-of-concept and feasibility (STANDby). Lancet Regional Health – Southeast Asia, 9, 100111. (doi: 10.1016/j.lansea.2022.100111) (PMID:36777452) (PMCID:PMC9904218)
Sullivan, M. K. et al. (2023) Potential impact of NICE guidelines on referrals from primary care to nephrology: a primary care database and prospective research study. British Journal of General Practice, 73(727), e141-e147. (doi: 10.3399/BJGP.2022.0145) (PMID:36376072) (PMCID:PMC9678375)
Sykes, R. et al. (2023) Adjudicated myocarditis and multisystem illness trajectory in healthcare workers post-COVID-19. Open Heart, 10(1), e002192. (doi: 10.1136/openhrt-2022-002192) (PMID:36822817) (PMCID:PMC9950584)
Welsh, P. and Sattar, N. (2023) To apoB or not to apoB: new arguments, but basis for widespread implementation remains elusive. Clinical Chemistry, 69(1), pp. 3-5. (doi: 10.1093/clinchem/hvac183) (PMID:36427190)
2022
Kilpi, F., Soares, A. G., Clayton, G. L., Fraser, A., Welsh, P. , Sattar, N. , Nelson, S. M. , Tilling, K. and Lawlor, D. A. (2022) Changes in women’s physical function in mid-life by reproductive age and hormones: a longitudinal study. BMC Women's Health, 22, 473. (doi: 10.1186/s12905-022-02070-9) (PMID:36434722) (PMCID:PMC9700972)
Paterson, C., Hinterberg, M. A., Morrow, A. J. , Sykes, R. , Mangion, K., Welsh, P. , McConnachie, A. , Sattar, N. , Berry, C. and Williams, S. A. (2022) Utility of a Proteomic Surrogate for Cardiovascular Outcomes to Predict and Monitor COVID-19 Induced Myocarditis. American Heart Association's 2022 Scientific Sessions and the American Heart Association's 2022 Resuscitation Science Symposium, Chicago, Illinois, USA, 04-07 Nov 2022. (doi: 10.1161/circ.146.suppl_1.12132)
Karusheva, Y. et al. (2022) Common H202D variant in GDF-15 does not affect its bioactivity but can significantly interfere with measurement of its circulating levels. Journal of Applied Laboratory Medicine, 7(6), pp. 1388-1400. (doi: 10.1093/jalm/jfac055) (PMID:35796717)
Welsh, P. et al. (2022) Reference ranges for NT-proBNP (N-terminal pro-B-type natriuretic peptide) and risk factors for higher NT-proBNP concentrations in a large general population cohort. Circulation: Heart Failure, 15(10), pp. 957-967. (doi: 10.1161/CIRCHEARTFAILURE.121.009427) (PMID:36098049) (PMCID:PMC9561238)
Docherty, K. F. et al. (2022) Iron deficiency in heart failure and effect of dapagliflozin: findings from DAPA-HF. Circulation, 146(13), pp. 980-994. (doi: 10.1161/CIRCULATIONAHA.122.060511) (PMID:35971840) (PMCID:PMC9508991)
Ho, F. K. et al. (2022) Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94 739 UK Biobank participants. Circulation, 146(12), pp. 883-891. (doi: 10.1161/CIRCULATIONAHA.122.059663) (PMID:36036153)
Clayton, G. L., Soares, A. G., Kilpi, F., Fraser, A., Welsh, P. , Sattar, N. , Nelson, S. M. , Tilling, K. and Lawlor, D. A. (2022) Cardiovascular health in the menopause transition: a longitudinal study of up to 3892 women with up to four repeated measures of risk factors. BMC Medicine, 20, 299. (doi: 10.1186/s12916-022-02454-6) (PMID:35974322) (PMCID:PMC9382827)
Lee, M. M.Y. et al. (2022) Effect of empagliflozin on kidney biochemical and imaging outcomes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF). Circulation, 146(4), pp. 364-367. (doi: 10.1161/CIRCULATIONAHA.122.059851) (PMID:35877829)
Kimenai, D. M. et al. (2022) Socioeconomic deprivation: an important, largely unrecognized risk factor in primary prevention of cardiovascular disease. Circulation, 146(3), pp. 240-248. (doi: 10.1161/CIRCULATIONAHA.122.060042) (PMID:35748241)
Colaço, K. et al. (2022) Association of cardiac biomarkers with cardiovascular outcomes in patients with psoriatic arthritis and psoriasis: a longitudinal cohort study. Arthritis and Rheumatology, 74(7), pp. 1184-1192. (doi: 10.1002/art.42079) (PMID:35261189)
Mangion, K. et al. (2022) Multi-system investigation of COVID-19 illness. British Cardiovascular Society Annual Conference, ‘100 years of Cardiology’, Manchester, UK, 06-08 June 2022. A122.1-A122. (doi: 10.1136/heartjnl-2022-BCS.157)
Ho, F. K. et al. (2022) Association of gamma-glutamyltransferase levels with total mortality, liver-related, and cardiovascular outcomes: a prospective cohort study in the UK Biobank. EClinicalMedicine, 48, 101435. (doi: 10.1016/j.eclinm.2022.101435) (PMID:35706481) (PMCID:PMC9112033)
Morrow, A. J. et al. (2022) A multisystem, cardio-renal investigation of post-COVID-19 illness. Nature Medicine, 28(6), pp. 1303-1313. (doi: 10.1038/s41591-022-01837-9) (PMID:35606551) (PMCID:PMC9205780)
Sattar, N. and Welsh, P. (2022) Risk scoring in secondary prevention: a basis for informed clinical decisions in the context of ever-expanding treatments. European Heart Journal, 43(18), pp. 1728-1730. (doi: 10.1093/eurheartj/ehac125) (PMID:35265991)
Petermann-Rocha, F., Gray, S. R. , Forrest, E., Welsh, P. , Sattar, N. , Celis-Morales, C. , Ho, F. K. and Pell, J. P. (2022) Associations of muscle mass and grip strength with severe NAFLD: a prospective study of 333,295 UK Biobank participants. Journal of Hepatology, 76(5), pp. 1021-1029. (doi: 10.1016/j.jhep.2022.01.010) (PMID:35085594)
Ho, F., Gray, S. R. , Welsh, P. , Gill, J. M.R. , Sattar, N. , Pell, J. P. and Celis-Morales, C. (2022) Ethnic differences in cardiovascular risk: examining differential exposure and susceptibility to risk factors. BMC Medicine, 20(1), 149. (doi: 10.1186/s12916-022-02337-w) (PMID:35473626) (PMCID:PMC9042646)
Said, S. et al. (2022) Genetic analysis of over half a million people characterises C-reactive protein loci. Nature Communications, 13, 2198. (doi: 10.1038/s41467-022-29650-5) (PMID:35459240) (PMCID:PMC9033829)
Ho, F. K., Celis-Morales, C. , Gray, S. R. , Demou, E. , Mackay, D. , Welsh, P. , Katikireddi, S. V. , Sattar, N. and Pell, J. P. (2022) Association and pathways between shift work and cardiovascular disease: a prospective cohort study of 238 661 participants from UK Biobank. International Journal of Epidemiology, 51(2), pp. 579-590. (doi: 10.1093/ije/dyab144) (PMID:34414428)
Ferguson, L. D. et al. (2022) Effect of the phosphodiesterase 4 inhibitor apremilast on cardiometabolic outcomes in psoriatic disease – results of the Immune Metabolic Associations in Psoriatic Arthritis study. Rheumatology, 61(3), pp. 1026-1034. (doi: 10.1093/rheumatology/keab474) (PMID:34097014) (PMCID:PMC8889283)
Aba Alkhayl, F. F. et al. (2022) Muscle protein synthesis and muscle/metabolic responses to resistance exercise training in South Asian and White European men. Scientific Reports, 12, 2469. (doi: 10.1038/s41598-022-06446-7) (PMID:35169204) (PMCID:PMC8847359)
Berg, D. D. et al. (2022) Serial assessment of high-sensitivity cardiac troponin and the effect of dapagliflozin in patients with heart failure with reduced ejection fraction: an analysis of the DAPA-HF trial. Circulation, 145(3), pp. 158-169. (doi: 10.1161/CIRCULATIONAHA.121.057852) (PMID:34743554)
Rodríguez-Gómez, I. et al. (2022) Osteoporosis and its association with cardiovascular disease, respiratory disease, and cancer: findings from the UK Biobank prospective cohort study. Mayo Clinic Proceedings, 97(1), pp. 110-121. (doi: 10.1016/j.mayocp.2021.07.019) (PMID:34996542)
Welsh, P. , Kimenai, D. M., Marioni, R. E., Hayward, C., Campbell, A., Porteous, D., Mills, N. L., O’Rahilly, S. and Sattar, N. (2022) Reference ranges for GDF-15, and risk factors associated with GDF-15, in a large general population cohort. Clinical Chemistry and Laboratory Medicine, 60(11), pp. 1820-1829. (doi: 10.1515/cclm-2022-0135) (PMID:35976089) (PMCID:PMC9524804)
2021
Petermann-Rocha, F. et al. (2021) Dose-response association between device-measured physical activity and incident dementia: a prospective study from UK Biobank. BMC Medicine, 19, 305. (doi: 10.1186/s12916-021-02172-5)
Kulkarni, S., Welsh, P. , Ali, M. and Petrie, J. R. (2021) Quality of life in people with type 2 diabetes; a study in a multi-ethnic clinical trial population. British Journal of Diabetes, 21(2), pp. 210-215. (doi: 10.15277/bjd.2021.315)
Macpherson, J. M. et al. (2021) Child maltreatment and incident mental disorders in middle and older ages: a retrospective UK Biobank cohort study. Lancet Regional Health - Europe, 11, 100224. (doi: 10.1016/j.lanepe.2021.100224) (PMID:34917999) (PMCID:PMC8642708)
Wannamethee, S. G., Welsh, P. , Papacosta, O., Lennon, L. and Whincup, P. (2021) Vitamin D deficiency, impaired lung function and total and respiratory mortality in a cohort of older men: cross-sectional and prospective findings from the British Regional Heart Study. BMJ Open, 11(12), e051560. (doi: 10.1136/bmjopen-2021-051560) (PMID:34933860) (PMCID:PMC8693094)
Welsh, P. et al. (2021) Lipoprotein(a) and cardiovascular disease: prediction, attributable risk fraction and estimating benefits from novel interventions. European Journal of Preventive Cardiology, 28(18), pp. 1991-2000. (doi: 10.1093/eurjpc/zwaa063) (PMID:33624048)
Berry, C. et al. (2021) Post-COVID-19 illness trajectory: a multisystem investigation [Pre-print]. Research Square, (doi: 10.21203/rs.3.rs-1053331/v1)
Morrow, A. et al. (2021) Rationale and design of the Medical Research Council Precision medicine with Zibotentan in microvascular angina (PRIZE) trial MRI sub-study. British Society of Cardiovascular Magnetic Resonance 2021 Annual Meeting, 12 October 2021. A2.1-A2. (doi: 10.1136/heartjnl-2021-BSCMR.3)
Colaco, K. et al. (2021) Targeted metabolomic profiling and prediction of cardiovascular events: a prospective study of patients with psoriatic arthritis and psoriasis. Annals of the Rheumatic Diseases, 80(11), pp. 1429-1435. (doi: 10.1136/annrheumdis-2021-220168) (PMID:34049856)
Sullivan, M. K. et al. (2021) Multimorbidity and the risk of major adverse kidney events: findings from the UK Biobank cohort. Clinical Kidney Journal, 14(11), pp. 2409-2419. (doi: 10.1093/ckj/sfab079) (PMCID:PMC8573008)
Al-Ozairi, E. et al. (2021) Risk of mortality among inpatients with COVID-19 and type 2 diabetes: national data from Kuwait. Endocrinology, Diabetes and Metabolism, 4(4), e00287. (doi: 10.1002/edm2.287) (PMID:34505420) (PMCID:PMC8420596)
Anderson, J. J. et al. (2021) Remote history of VTE is associated with severe COVID-19 in middle and older age: UK Biobank cohort study. Journal of Thrombosis and Haemostasis, 19(10), pp. 2533-2538. (doi: 10.1111/jth.15452) (PMID:34242477) (PMCID:PMC8420476)
Jani, B. D. et al. (2021) Family history of diabetes and risk of SARS-COV-2 in UK Biobank: a prospective cohort study. Endocrinology, Diabetes and Metabolism, 4(4), e00283. (doi: 10.1002/edm2.283) (PMID:34505416) (PMCID:PMC8420405)
Brown, R., Lewsey, J. , Wild, S., Logue, J. and Welsh, P. (2021) Associations of statin adherence and lipid targets with adverse outcomes in myocardial infarction survivors: a retrospective cohort study. BMJ Open, 11(9), e054893. (doi: 10.1136/bmjopen-2021-054893) (PMID:34580105) (PMCID:PMC8477332)
Stoumpos, S. et al. (2021) Interrogating the haemodynamic effects of haemodialysis arteriovenous fistula on cardiac structure and function. Scientific Reports, 11, 18102. (doi: 10.1038/s41598-021-97625-5) (PMID:34518583) (PMCID:PMC8437985)
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Petermann-Rocha, F., Parra-Soto, S., Gray, S. , Anderson, J. , Welsh, P. , Gill, J. , Sattar, N. , Ho, F. K., Celis-Morales, C. and Pell, J. P. (2021) Vegetarians, fish, poultry and meat-eaters: who has higher risk of CVD incidence and mortality? A prospective study from UK Biobank. European Heart Journal, 42(12), pp. 1136-1143. (doi: 10.1093/eurheartj/ehaa939) (PMID:33313747)
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2020
Brown, R., Welsh, P. and Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events. Open Heart, 7(2), e001396. (doi: 10.1136/openhrt-2020-001396) (PMID:33443127) (PMCID:PMC7751215)
Goncalves Soares, A., Kilpi, F., Fraser, A., Nelson, S. M. , Sattar, N. , Welsh, P. I. , Tilling, K. and Lawlor, D. A. (2020) Longitudinal changes in reproductive hormones through the menopause transition in the Avon Longitudinal Study of Parents and Children (ALSPAC). Scientific Reports, 10, 21258. (doi: 10.1038/s41598-020-77871-9) (PMID:33277550) (PMCID:PMC7718240)
Ferguson, A. C. et al. (2020) Association of SBP and BMI with cognitive and structural brain phenotypes in UK Biobank. Journal of Hypertension, 38(12), pp. 2482-2489. (doi: 10.1097/HJH.0000000000002579) (PMID:32665523)
Ho, F. K. et al. (2020) Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study. BMJ Open, 10, e040402. (doi: 10.1136/bmjopen-2020-040402) (PMID:33444201) (PMCID:PMC7678347)
Petermann-Rocha, F. et al. (2020) Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank. BMC Medicine, 18, 355. (doi: 10.1186/s12916-020-01822-4) (PMID:33167965) (PMCID:PMC7652674)
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McCartney, P. J. et al. (2020) Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT. Efficacy and Mechanism Evaluation, 7(5), (doi: 10.3310/eme07050) (PMID:33175484)
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Cameron, A. C. et al. (2020) Comprehensive characterisation of the vascular effects of cisplatin-based chemotherapy in patients with testicular cancer. JACC: CardioOncology, 2(3), pp. 443-455. (doi: 10.1016/j.jaccao.2020.06.004) (PMID:33043304) (PMCID:PMC7539369)
Sattar, N. et al. (2020) BMI and future risk for COVID-19 infection and death across sex, age and ethnicity: preliminary findings from UK biobank. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14(5), pp. 1149-1151. (doi: 10.1016/j.dsx.2020.06.060) (PMID:32668401) (PMCID:PMC7326434)
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Ferguson, A. C. et al. (2020) Alzheimer’s disease susceptibility gene apolipoprotein e (APOE) and blood biomarkers in UK Biobank (N=395,769). Journal of Alzheimer's Disease, 76(4), pp. 1541-1551. (doi: 10.3233/JAD-200338) (PMID:32651323)
Campbell, R. T. et al. (2020) The novel urinary proteomic classifier HF1 has similar diagnostic and prognostic utility to BNP in heart failure. ESC Heart Failure, 7(4), pp. 1595-1604. (doi: 10.1002/ehf2.12708) (PMID:32383555) (PMCID:PMC7373887)
Harris, K. et al. (2020) Plasma fatty acids and the risk of vascular disease and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE study. Diabetologia, 63, pp. 1637-1647. (doi: 10.1007/s00125-020-05162-z) (PMID:32385604) (PMCID:PMC7351876)
Petermann-Rocha, F., Ho, K. F., Welsh, P. , Mackay, D. , Brown, R., Gill, J. M.R. , Sattar, N. , Gray, S. R. , Pell, J. P. and Celis-Morales, C. A. (2020) Physical capability markers used to define sarcopenia and their association with cardiovascular and respiratory outcomes and all-cause mortality: a prospective study from UK Biobank. Maturitas, 138, pp. 69-75. (doi: 10.1016/j.maturitas.2020.04.017) (PMID:32471663)
Wright, A. K., Welsh, P. , Gill, J. M.R. , Kontopantelis, E., Emsley, R., Buchan, I., Ashcroft, D. M., Rutter, M. K. and Sattar, N. (2020) Age-, sex- and ethnicity-related differences in body weight, blood pressure, HbA1c and lipid levels at the diagnosis of type 2 diabetes relative to people without diabetes. Diabetologia, 63, pp. 1542-1553. (doi: 10.1007/s00125-020-05169-6) (PMID:32435821) (PMCID:PMC7351865)
Sattar, N. and Welsh, P. (2020) The obesity paradox in secondary prevention: a weighty intervention or a wait for more evidence? European Heart Journal, 41(28), pp. 2678-2680. (doi: 10.1093/eurheartj/ehaa398) (PMID:32459827)
Hastie, C. E. et al. (2020) Vitamin D concentrations and COVID-19 infection in UK Biobank. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14(4), pp. 561-565. (doi: 10.1016/j.dsx.2020.04.050) (PMID:32413819) (PMCID:PMC7204679)
Al Ozairi, E. et al. (2020) Protocol for a randomised controlled trial to investigate the effect of home and gym-based resistance exercise training on glycaemic control, body composition and muscle strength. Trials, 21, 557. (doi: 10.1186/s13063-020-04480-2) (PMID:32571396) (PMCID:PMC7310149)
Niedzwiedz, C. L. et al. (2020) Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank. BMC Medicine, 18, 160. (doi: 10.1186/s12916-020-01640-8) (PMID:32466757) (PMCID:PMC7255908)
Welsh, C. E. et al. (2020) Grip strength and walking pace and cardiovascular disease risk prediction in 406,834 UK Biobank participants. Mayo Clinic Proceedings, 95(5), pp. 879-888. (doi: 10.1016/j.mayocp.2019.12.032) (PMID:32299669)
Anderson, J. J. , Gray, S. R. , Welsh, P. , Mackay, D. F. , Celis-Morales, C. A. , Lyall, D. M. , Forbes, J., Sattar, N. , Gill, J. M.R. and Pell, J. P. (2020) The associations of sugar-sweetened, artificially sweetened and naturally sweet juices with all-cause mortality in 198,285 UK Biobank participants: a prospective cohort study. BMC Medicine, 18(1), 97. (doi: 10.1186/s12916-020-01554-5) (PMID:32326961)
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Ho, F. K. et al. (2020) Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants. British Medical Journal, 368(8238), m688. (doi: 10.1136/bmj.m688) (PMID:32188587)
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Maznyczka, A. M. et al. (2020) Effects of intracoronary alteplase on microvascular function in acute myocardial infarction. Journal of the American Heart Association, 9(3), e014066. (doi: 10.1161/JAHA.119.014066) (PMID:31986989) (PMCID:PMC7033872)
Cameron, A. C., Welsh, P. , Neves, K. B. , Newby, D., Touyz, R. M. and Lang, N. (2020) Acute vascular effects of vascular endothelial growth factor inhibition in the forearm arterial circulation. Journal of Hypertension, 38(2), pp. 257-265. (doi: 10.1097/HJH.0000000000002230) (PMID:31449168) (PMCID:PMC7197298)
Welsh, C. et al. (2020) Glycated hemoglobin, prediabetes and the links to cardiovascular disease: data from UK Biobank. Diabetes Care, 43(2), pp. 440-445. (doi: 10.2337/dc19-1683) (PMID:31852727)
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2019
Eastwood, S. V., Chaturvedi, N., Sattar, N. , Welsh, P. I. , Hughes, A. D. and Tillin, T. (2019) Impact of kidney function on cardiovascular risk and mortality: a comparison of South Asian and European cohorts. American Journal of Nephrology, 50(6), pp. 425-433. (doi: 10.1159/000503873) (PMID:31665726) (PMCID:PMC6892637)
Ferguson, L. D. , Brown, R., Celis-Morales, C. , Welsh, P. , Lyall, D. M. , Pell, J. P. , McInnes, I. B. , Siebert, S. and Sattar, N. (2019) Association of central adiposity with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional study of the UK Biobank. Rheumatology, 58(12), pp. 2137-2142. (doi: 10.1093/rheumatology/kez192) (PMID:31131407) (PMCID:PMC6880847)
Tillin, T. et al. (2019) Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care versus usual care alone following an acute coronary event. BMJ Open, 9(11), e030119. (doi: 10.1136/bmjopen-2019-030119) (PMID:31685500) (PMCID:PMC6858127)
Ferguson, L. , Welsh, P. , Brown, R., Tindell, A., Kerrigan, S., Sattar, N. , McInnes, I. and Siebert, S. (2019) Effect of Phosphodiesterase 4 Inhibition with Apremilast on Cardiometabolic Outcomes in Psoriatic Arthritis – Initial Results from the Immune Metabolic Associations in Psoriatic Arthritis (IMAPA) Study. In: 2019 ACR/ARP Annual Meeting, Atlanta, GA, 8-13 November 2019,
Lees, J. S. et al. (2019) Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease. Nature Medicine, 25, pp. 1753-1760. (doi: 10.1038/s41591-019-0627-8) (PMID:31700174) (PMCID:PMC6858876)
Sillars, A. et al. (2019) Association of fitness and grip-strength with heart failure: findings from the UK Biobank population-based study. Mayo Clinic Proceedings, 94(11), pp. 2230-2240. (doi: 10.1016/j.mayocp.2019.04.041) (PMID:31685151)
Steell, L. et al. (2019) Dose-response associations of cardiorespiratory fitness with all-cause mortality and incidence and mortality of cancer and cardiovascular and respiratory diseases: the UK Biobank cohort study. British Journal of Sports Medicine, 53(21), pp. 1371-1378. (doi: 10.1136/bjsports-2018-099093) (PMID:30796106)
Muilwijk, M. et al. (2019) Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study. BMJ Open Diabetes Research and Care, 7(1), e000765. (doi: 10.1136/bmjdrc-2019-000765) (PMID:31908795) (PMCID:PMC6936483)
Ho, F. K.W. et al. (2019) The association between handgrip strength and future health outcomes does not differ if grip strength is used in absolute or relative terms: a prospective cohort study. Age and Ageing, 48(5), pp. 683-691. (doi: 10.1093/ageing/afz068) (PMID:31204772)
Welsh, C. et al. (2019) Comparison of conventional lipoprotein tests and apolipoproteins in the prediction of cardiovascular disease: data from UK Biobank. Circulation, 140(7), pp. 542-552. (doi: 10.1161/CIRCULATIONAHA.119.041149) (PMID:31216866) (PMCID:PMC6693929)
Gray, S. et al. (2019) Do physical activity, commuting mode, cardiorespiratory fitness and sedentary behaviours modify the genetic predisposition to higher BMI? Findings from a UK Biobank study. International Journal of Obesity, 43, pp. 1526-1538. (doi: 10.1038/s41366-019-0381-5) (PMID:31168053)
Welsh, C. E. , Welsh, P. , Jhund, P. , Sattar, N. and Mark, P. B. (2019) Response by Welsh et al to letter regarding article “Urinary sodium excretion, blood pressure, and risk of future cardiovascular disease and mortality in subjects without prior cardiovascular disease”. Hypertension, 74, e27-e28. (doi: 10.1161/HYPERTENSIONAHA.119.13349) (PMID:31230548)
Haig, C. et al. (2019) Current smoking and prognosis after acute ST-segment elevation myocardial infarction: new pathophysiological insights. JACC: Cardiovascular Imaging, 12(6), pp. 993-1003. (doi: 10.1016/j.jcmg.2018.05.022) (PMID:30031700) (PMCID:PMC6547246)
Welsh, C. et al. (2019) Urinary sodium excretion, blood pressure and risk of future cardiovascular disease and mortality in subjects without prior cardiovascular disease. Hypertension, 73, pp. 1202-1209. (doi: 10.1161/HYPERTENSIONAHA.119.12726) (PMID:31067194)
Welsh, P. et al. (2019) Cardiac troponin T and troponin I in the general population: comparing and contrasting their genetic determinants and associations with outcomes. Circulation, 139(24), pp. 2754-2764. (doi: 10.1161/CIRCULATIONAHA.118.038529) (PMID:31014085) (PMCID:PMC6571179)
Lean, M. E.J. et al. (2019) Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial. Lancet Diabetes and Endocrinology, 7(5), pp. 344-355. (doi: 10.1016/S2213-8587(19)30068-3) (PMID:30852132)
Celis-Morales, C. A. et al. (2019) The combination of physical activity and sedentary behaviors modifies the genetic predisposition to obesity. Obesity, 27(4), pp. 653-661. (doi: 10.1002/oby.22417) (PMID:30900409)
Kuh, D., Cooper, R., Sattar, N. , Welsh, P. , Hardy, R. and Ben-Shlomo, Y. (2019) Systemic inflammation and cardio-renal organ damage biomarkers in middle age are associated with physical capability up to 9 years later: findings from a British birth cohort study. Circulation, 139(17), pp. 1988-1999. (doi: 10.1161/CIRCULATIONAHA.118.037332) (PMID:30667283) (PMCID:PMC6485301)
Maznyczka, A. M. et al. (2019) Sex-based associations with microvascular injury and outcomes after ST-segment elevation myocardial infarction. Open Heart, 6(1), e000979. (doi: 10.1136/openhrt-2018-000979) (PMID:31168381) (PMCID:PMC6519583)
Welsh, P. , Papacosta, O., Ramsay, S., Whincup, P., McMurray, J. , Wannamethee, G. and Sattar, N. (2019) High sensitivity troponin T and incident heart failure in older men: British Regional Heart Study. Journal of Cardiac Failure, 25(4), pp. 230-237. (doi: 10.1016/j.cardfail.2018.08.002) (PMID:30103019) (PMCID:PMC7083232)
Rankin, N. J. , Burgess, K., Weidt, S., Wannamethee, G., Sattar, N. and Welsh, P. (2019) High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry. Annals of Clinical Biochemistry, 56(3), pp. 397-407. (doi: 10.1177/0004563219830432) (PMID:30832481) (PMCID:PMC6498755)
Celis-Morales, C. A. et al. (2019) Walking pace is associated with lower risk of all-cause and cause-specific mortality. Medicine and Science in Sports and Exercise, 51(3), pp. 472-480. (doi: 10.1249/MSS.0000000000001795) (PMID:30303933)
Steell, L. , Sillars, A., Welsh, P. , Iliodromiti, S., Wong, S.C. , Pell, J.P. , Sattar, N. , Gill, J.M.R. , Celis, C. and Gray, S.R. (2019) Associations of dietary protein intake with bone mineral density: an observational study in 70,215 UK Biobank participants. Bone, 120, pp. 38-43. (doi: 10.1016/j.bone.2018.10.003) (PMID:30292817)
McCartney, P. J. et al. (2019) Effect of low-dose intracoronary alteplase during primary percutaneous coronary intervention on microvascular obstruction in patients with acute myocardial infarction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321(1), pp. 56-68. (doi: 10.1001/jama.2018.19802) (PMID:30620371) (PMCID:PMC6583564)
Sabater-Lleal, M. et al. (2019) Genome-wide association transethnic meta-analyses identifies novel associations regulating coagulation factor VIII and von Willebrand factor plasma levels. Circulation, 139(5), pp. 620-635. (doi: 10.1161/CIRCULATIONAHA.118.034532) (PMID:30586737) (PMCID:PMC6438386)
Welsh, P. and Iliodromiti, S. (2019) Epidemiology of vascular diseases. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 299-306. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_28)
2018
Chauhan, A. et al. (2018) Scientific Business Abstracts of the 112th Annual Meeting of the Association of Physicians of Great Britain and Ireland. QJM: An International Journal of Medicine, 111(12), pp. 920-924. (doi: 10.1093/qjmed/hcy193) (PMID:31222346)
Celis-Morales, C.A. et al. (2018) Associations of dietary protein intake with fat free mass and grip strength: cross-sectional study in 146,816 UK Biobank participants. American Journal of Epidemiology, 187(11), pp. 2405-2414. (doi: 10.1093/aje/kwy134) (PMID:29961893)
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Welsh, P. et al. (2018) Comparison between high-sensitivity cardiac troponin T and cardiac troponin I in a large general population cohort. Clinical Chemistry, 64(11), pp. 1607-1616. (doi: 10.1373/clinchem.2018.292086) (PMID:30126950)
Carberry, J. et al. (2018) Persistent iron within the infarct core after ST-segment elevation myocardial infarction: implications for left ventricular remodeling and health outcomes. JACC: Cardiovascular Imaging, 11(9), pp. 1248-1256. (doi: 10.1016/j.jcmg.2017.08.027) (PMID:29153575) (PMCID:PMC6130225)
Carrick, D. et al. (2018) Hypertension, microvascular pathology and prognosis after an acute myocardial infarction. Hypertension, 72(3), pp. 720-730. (doi: 10.1161/HYPERTENSIONAHA.117.10786) (PMID:30012869) (PMCID:PMC6080885)
Bodde, M. C., Welsh, P. , Bergheanu, S. C., Lijfering, W. M., Mertens, B., Liem, A.-H., van der Laarse, A., Sattar, N. and Jukema, J.W. (2018) A rapid (differential) effect of rosuvastatin and atorvastatin on high-sensitivity cardiac Troponin-I in subjects with stable cardiovascular disease. Clinical Pharmacology and Therapeutics, 104(2), pp. 311-316. (doi: 10.1002/cpt.1095) (PMID:29672821)
Jenkins, A. J., Welsh, P. and Petrie, J. R. (2018) Metformin, lipids and atherosclerosis prevention. Current Opinion in Lipidology, 29(4), pp. 346-353. (doi: 10.1097/MOL.0000000000000532) (PMID:29878903)
Colombo, M. et al. (2018) Apolipoprotein CIII and N-terminal prohormone b-type natriuretic peptide as independent predictors for cardiovascular disease in type 2 diabetes. Atherosclerosis, 274, pp. 182-190. (doi: 10.1016/j.atherosclerosis.2018.05.014) (PMID:29793175)
Welsh, P. et al. (2018) Circulating amino acids and the risk of macrovascular, microvascular, and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial. Diabetologia, 61(7), pp. 1581-1591. (doi: 10.1007/s00125-018-4619-x) (PMID:29728717) (PMCID:PMC6445481)
Welsh, C. et al. (2018) Association of total and differential leukocyte counts with cardiovascular disease and mortality in the UK Biobank. Arteriosclerosis, Thrombosis, and Vascular Biology, 38(6), pp. 1415-1423. (doi: 10.1161/ATVBAHA.118.310945) (PMID:29699973)
Celis-Morales, C. et al. (2018) Associations of discretionary screen time with mortality, cardiovascular disease and cancer are attenuated by strength, fitness and physical activity: findings from the UK Biobank study. BMC Medicine, 16, 77. (doi: 10.1186/s12916-018-1063-1) (PMID:29792209) (PMCID:PMC5966877)
Celis-Morales, C. A. et al. (2018) Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants. British Medical Journal, 361, k1651. (doi: 10.1136/bmj.k1651) (PMID:29739772) (PMCID:PMC5939721)
Iliodromiti, S. et al. (2018) The impact of confounding on the associations of different adiposity measures with the incidence of cardiovascular disease: a cohort study of 296 535 adults of white European descent. European Heart Journal, 39(17), pp. 1514-1520. (doi: 10.1093/eurheartj/ehy057) (PMID:29718151) (PMCID:PMC5930252)
Botha, S., Forde, L., MacNaughton, S., Shearer, R., Lindsay, R. , Sattar, N. , Morrison, D., Welsh, P. and Logue, J. (2018) The effect of non-surgical weight management on weight and glycaemic control in people with type 2 diabetes: a comparison of interventional and non-interventional outcomes at three years. Diabetes, Obesity and Metabolism, 20(4), pp. 879-888. (doi: 10.1111/dom.13171) (PMID:29178635)
Delles, C. et al. (2018) Nuclear magnetic resonance-based metabolomics identifies phenylalanine as a novel predictor of incident heart failure hospitalisation: results from PROSPER and FINRISK 1997. European Journal of Heart Failure, 20, pp. 663-673. (doi: 10.1002/ejhf.1076) (PMID:29226610) (PMCID:PMC5947152)
Parsons, T. J., Sartini, C., Welsh, P. , Sattar, N. , Ash, S., Lennon, L. T., Wannamethee, S. G., Lee, I.-M., Whincup, P. H. and Jefferis, B. J. (2018) Objectively measured physical activity and cardiac biomarkers: A cross sectional population based study in older men. International Journal of Cardiology, 254, pp. 322-327. (doi: 10.1016/j.ijcard.2017.11.003) (PMID:29407114) (PMCID:PMC5958950)
Taylor, R. et al. (2018) Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort. Diabetologia, 61(3), pp. 589-598. (doi: 10.1007/s00125-017-4503-0) (PMID:29188339)
Lean, M. E.J. et al. (2018) Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. Lancet, 391(10120), pp. 541-551. (doi: 10.1016/S0140-6736(17)33102-1) (PMID:29221645)
Corcoran, D. et al. (2018) The effects of remote ischaemic preconditioning on coronary artery function in patients with stable coronary artery disease. International Journal of Cardiology, 252, pp. 24-30. (doi: 10.1016/j.ijcard.2017.10.082) (PMID:29249435) (PMCID:PMC5761717)
Stoumpos, S., Lees, J. , Welsh, P. , Hund, M., Geddes, C. C., Nelson, S. M. and Mark, P. B. (2018) The utility of anti-Müllerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation. Reproductive BioMedicine Online, 36(2), pp. 219-226. (doi: 10.1016/j.rbmo.2017.11.003) (PMID:29233504)
Welsh, P. (2018) Correlating changes in metabolic status with arterial health: modest associations but any clinical implications? Hypertension, 71(2), pp. 227-228. (doi: 10.1161/HYPERTENSIONAHA.117.10595) (PMID:29279313)
Welsh, P. et al. (2018) Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. European Journal of Heart Failure, 20(2), pp. 268-277. (doi: 10.1002/ejhf.988) (PMID:28960777) (PMCID:PMC6607475)
Patel, N., Hellmuth, C., Uhl, O., Godfrey, K., Briley, A., Welsh, P. , Pasupathy, D., Seed, P., Koletzko, B. and Poston, L. (2018) Cord metabolic profiles In obese pregnant women; insights into offspring growth and body composition. Journal of Clinical Endocrinology and Metabolism, 103(1), pp. 346-355. (doi: 10.1210/jc.2017-00876) (PMID:29140440)
2017
Carberry, J. et al. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10(12), e006586. (doi: 10.1161/CIRCIMAGING.117.006586) (PMID:29242240) (PMCID:PMC5753833)
Celis-Morales, C. A. et al. (2017) Associations between diabetes and both cardiovascular disease and all-cause mortality are modified by grip strength: evidence from UK Biobank, a prospective population-based cohort study. Diabetes Care, 40(12), pp. 1710-1718. (doi: 10.2337/dc17-0921) (PMID:28986505)
Vieira, M. C. et al. (2017) Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study. BMC Medicine, 15, 194. (doi: 10.1186/s12916-017-0956-8) (PMID:29096631) (PMCID:PMC5669007)
Sartini, C., Whincup, P. H., Wannamethee, S. G., Jefferis, B. J., Lennon, L., Lowe, G. D.O., Welsh, P. , Sattar, N. and Morris, R. W. (2017) Associations of time of day with cardiovascular disease risk factors measured in older men: results from the British Regional Heart Study. BMJ Open, 7(11), e018264. (doi: 10.1136/bmjopen-2017-018264) (PMID:29133328) (PMCID:PMC5695475)
Welsh, P. , Grassia, G., Botha, S., Sattar, N. and Maffia, P. (2017) Targeting inflammation to reduce cardiovascular disease risk: a realistic clinical prospect? British Journal of Pharmacology, 174(22), pp. 3898-3913. (doi: 10.1111/bph.13818) (PMID:28409825) (PMCID:PMC5660005)
Rutherford, E. et al. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, 13976. (doi: 10.1038/s41598-017-14481-y) (PMID:29070834) (PMCID:PMC5656609)
White, S. L., Pasupathy, D., Sattar, N. , Nelson, S. M. , Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P. and Poston, L. (2017) Metabolic profiling of gestational diabetes in obese women during pregnancy. Diabetologia, 60(10), pp. 1903-1912. (doi: 10.1007/s00125-017-4380-6) (PMID:28766127)
Price, A. H., Weir, C. J., Welsh, P. , McLachlan, S., Strachan, M. W.J., Sattar, N. and Price, J. F. (2017) Comparison of non-traditional biomarkers, and combinations of biomarkers, for vascular risk prediction in people with type 2 diabetes: The Edinburgh Type 2 Diabetes Study. Atherosclerosis, 264, pp. 67-73. (doi: 10.1016/j.atherosclerosis.2017.07.009) (PMID:28777936) (PMCID:PMC5603967)
Wannamethee, S. G., Welsh, P. , Papacosta, O., Ellins, E. A., Halcox, J. P.J., Whincup, P. H. and Sattar, N. (2017) Circulating soluble receptor for advanced glycation end product: cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis, 264, pp. 36-43. (doi: 10.1016/j.atherosclerosis.2017.07.008) (PMID:28759844) (PMCID:PMC5603971)
Willeit, P. et al. (2017) High-sensitivity cardiac troponin concentration and risk of first-ever cardiovascular outcomes: literature-based meta-analysis involving 154,052 participants. Journal of the American College of Cardiology, 70(5), pp. 558-568. (doi: 10.1016/j.jacc.2017.05.062) (PMID:28750699) (PMCID:PMC5527070)
Jenks, S. J., Conway, B. R., McLachlan, S., Teoh, W. L., Williamson, R. M., Webb, D. J., Welsh, P. , Sattar, N. , Strachan, M. W.J. and Price, J. F. (2017) Cardiovascular disease biomarkers are associated with declining renal function in type 2 diabetes. Diabetologia, 60(8), pp. 1400-1408. (doi: 10.1007/s00125-017-4297-0) (PMID:28528401) (PMCID:PMC5491560)
Ohkuma, T. et al. (2017) Cardiac stress and inflammatory markers as predictors of heart failure in patients with type 2 diabetes: the ADVANCE trial. Diabetes Care, 40(9), pp. 1203-1209. (doi: 10.2337/dc17-0509) (PMID:28684396)
Celis-Morales, C. A. et al. (2017) Association between active commuting and incident cardiovascular disease, cancer, and mortality: prospective cohort study. British Medical Journal, 357, j1456. (doi: 10.1136/bmj.j1456) (PMID:28424154)
Carty, D. M., Doogan, F., Welsh, P. , Dominiczak, A. F. and Delles, C. (2017) Thyroid stimulating hormone (TSH) ≥2.5mU/l in early pregnancy: prevalence and subsequent outcomes. European Journal of Obstetrics and Gynecology and Reproductive Biology, 210, pp. 366-369. (doi: 10.1016/j.ejogrb.2017.01.048) (PMID:28153744)
Parsons, T. J., Sartini, C., Welsh, P. , Sattar, N. , Ash, S., Lennon, L. T., Wannamethee, S. G., Lee, I.-M., Whincup, P. H. and Jefferis, B. J. (2017) Physical activity, sedentary behavior, and inflammatory and hemostatic markers in men. Medicine and Science in Sports and Exercise, 49(3), pp. 459-465. (doi: 10.1249/MSS.0000000000001113) (PMID:28222056)
Preiss, D. et al. (2017) Sustained influence of metformin therapy on circulating glucagon-like peptide-1 levels in individuals with and without type 2 diabetes. Diabetes, Obesity and Metabolism, 19(3), pp. 356-363. (doi: 10.1111/dom.12826) (PMID:27862873) (PMCID:PMC5330429)
Sartini, C. et al. (2017) Relationship between outdoor temperature and cardiovascular disease risk factors in older people. European Journal of Preventive Cardiology, 24(4), pp. 349-356. (doi: 10.1177/2047487316682119) (PMID:27899528)
Celis-Morales, C. et al. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi: 10.1038/ijo.2017.169) (PMID:28736445)
2016
White, S. L. et al. (2016) Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention. PLoS ONE, 11(12), e0167846. (doi: 10.1371/journal.pone.0167846) (PMID:27930697) (PMCID:PMC5145208)
Preiss, D. , Rankin, N. , Welsh, P. , Holman, R.R., Kangas, A.J., Soininen, P., Würtz, P., Ala-Korpela, M. and Sattar, N. (2016) Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study. Diabetic Medicine, 33(11), pp. 1569-1574. (doi: 10.1111/dme.13097) (PMID:26887663)
Welsh, P. , Tuckwell, K., McInnes, I. B. and Sattar, N. (2016) Effect of IL-6 receptor blockade on high-sensitivity troponin T and NT-proBNP in rheumatoid arthritis. Atherosclerosis, 254, pp. 167-171. (doi: 10.1016/j.atherosclerosis.2016.10.016) (PMID:27744141) (PMCID:PMC5110649)
Rutherford, E. et al. (2016) Definition of myocardial tissue abnormalities in end stage renal failure with cardiac magnetic resonance imaging using T1 mapping. Kidney International, 90(4), pp. 845-852. (doi: 10.1016/j.kint.2016.06.014)
Willeit, P. et al. (2016) Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis. Lancet Diabetes and Endocrinology, 4(10), pp. 840-849. (doi: 10.1016/S2213-8587(16)30196-6) (PMID:27599814) (PMCID:PMC5035346)
Wijsman, L. W. et al. (2016) High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk. European Journal of Preventive Cardiology, 23(13), pp. 1383-1392. (doi: 10.1177/2047487316632364) (PMID:26884081)
Carberry, J. et al. (2016) Remote zone extracellular volume and left ventricular remodeling in survivors of st-elevation myocardial infarction. Hypertension, 68(2), pp. 385-391. (doi: 10.1161/HYPERTENSIONAHA.116.07222) (PMID:27354423) (PMCID:PMC4956675)
Preiss, D. , Welsh, P. and Sattar, N. (2016) Metformin therapy and circulating NT-proBNP levels: the CAMERA trial. Diabetes Care, 39(8), e114-e115. (doi: 10.2337/dc16-0887) (PMID:27271181)
Khamis, R. Y. et al. (2016) High serum immunoglobulin g and m levels predict freedom from adverse cardiovascular events in hypertension: a nested case-control substudy of the Anglo-Scandinavian cardiac outcomes trial. EBioMedicine, 9, pp. 372-380. (doi: 10.1016/j.ebiom.2016.06.012) (PMID:27333022) (PMCID:PMC4972545)
Wannamethee, S. G., Welsh, P. , Lennon, L., Papacosta, O., Whincup, P. and Sattar, N. (2016) Copeptin and risk of incident stroke, coronary heart disease and cardiovascular mortality in older men with and without diabetes: The British Regional Heart Study. Diabetologia, 59(p), pp. 1904-1912. (doi: 10.1007/s00125-016-4011-7) (PMID:27312697) (PMCID:PMC4969339)
Wannamethee, G., Shaper, G., Papacosta, O., Lennon, L., Welsh, P. and Whincup, P. (2016) Lung function and airway obstruction: associations with circulating markers of cardiac function and incident heart failure in older men—the British regional heart study. Thorax, 71(6), pp. 526-534. (doi: 10.1136/thoraxjnl-2014-206724) (PMID:26811343) (PMCID:PMC4893123)
Welsh, P. et al. (2016) Associations between weight change and biomarkers of cardiometabolic risk in South Asians: secondary analyses of the PODOSA Trial. International Journal of Obesity, 40(6), pp. 1005-1011. (doi: 10.1038/ijo.2016.35) (PMID:26927315) (PMCID:PMC4892347)
Ballantyne, M. D. et al. (2016) Smooth muscle enriched long noncoding RNA (SMILR) regulates cell proliferation. Circulation, 133(21), pp. 2050-2065. (doi: 10.1161/circulationaha.115.021019) (PMID:27052414) (PMCID:PMC4872641)
Carrick, D. et al. (2016) Microvascular resistance of the culprit coronary artery in acute ST-elevation myocardial infarction. JCI Insight, 1(6), e85768. (doi: 10.1172/jci.insight.85768) (PMID:27699259) (PMCID:PMC5033815)
Carrick, D. et al. (2016) Prognostic significance of infarct core pathology revealed by quantitative non-contrast in comparison to contrast cardiac magnetic resonance imaging in reperfused ST-elevation myocardial infarction survivors. European Heart Journal, 37(13), pp. 1044-1059. (doi: 10.1093/eurheartj/ehv372) (PMID:26261290) (PMCID:PMC4816961)
Loomis, A. K. et al. (2016) Body mass index and risk of non-alcoholic fatty liver disease: two electronic health record prospective studies. Journal of Clinical Endocrinology and Metabolism, 101(3), pp. 945-952. (doi: 10.1210/jc.2015-3444) (PMID:26672639) (PMCID:PMC4803162)
Carrick, D. et al. (2016) Temporal evolution of myocardial hemorrhage and edema in patients after acute ST-elevation myocardial infarction: pathophysiologic insights and clinical implications. Journal of the American Heart Association, 5, e002834. (doi: 10.1161/JAHA.115.002834) (PMID:26908408) (PMCID:PMC4802451)
Welsh, P. et al. (2016) Prediction of cardiovascular disease risk by cardiac biomarkers in 2 United Kingdom cohort studies: does utility depend on risk thresholds for treatment? Hypertension, 2016(67), pp. 309-315. (doi: 10.1161/HYPERTENSIONAHA.115.06501) (PMID:26667414) (PMCID:PMC4716288)
Carrick, D. et al. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9(1), e004148. (doi: 10.1161/CIRCIMAGING.115.004148) (PMID:26763281) (PMCID:PMC4718183)
Jackson, C. E. et al. (2016) The incremental prognostic and clinical value of multiple novel biomarkers in heart failure. European Journal of Heart Failure, 18(12), pp. 1491-1498. (doi: 10.1002/ejhf.543) (PMID:27114189)
Rankin, N. J. , Preiss, D. , Welsh, P. and Sattar, N. (2016) Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future. International Journal of Epidemiology, 45(5), pp. 1351-1371. (doi: 10.1093/ije/dyw271) (PMID:27789671) (PMCID:PMC5100629)
2015
Wannamethee, S. G., Welsh, P. , Papacosta, O., Lennon, L., Whincup, P. H. and Sattar, N. (2015) Copeptin, insulin resistance, and risk of incident diabetes in older men. Journal of Clinical Endocrinology and Metabolism, 100(9), pp. 3332-3339. (doi: 10.1210/JC.2015-2362) (PMID:26158609) (PMCID:PMC4570154)
Jackson, C. E. et al. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3(8), pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014) (PMID:26251088)
Carrick, D. et al. (2015) Pathophysiology of LV remodeling in survivors of STEMI : inflammation, remote myocardium, and prognosis. JACC: Cardiovascular Imaging, 8(7), pp. 779-789. (doi: 10.1016/j.jcmg.2015.03.007) (PMID:26093923) (PMCID:PMC4509710)
McArthur, L. , Johnston, L., Sattar, N. , Logue, J. and Welsh, P. (2015) Preanalytical study of fetuin-A: effect of sample type, processing speed and freeze-thaw cycles. Annals of Clinical Biochemistry, 52(1), pp. 165-168. (doi: 10.1177/0004563214529550) (PMID:24696154)
Sattar, N. , Welsh, P. and Preiss, D. (2015) The insulin resistance syndrome. In: DeFronzo, R. A., Ferrannini, E., Alberti, K.G.M.M. and Zimmet, P. (eds.) International Textbook of Diabetes Mellitus. John Wiley & Sons, Ltd, pp. 337-353. ISBN 9781118387658 (doi: 10.1002/9781118387658.ch23)
Welsh, P. , Preiss, D. and Touyz, R. M. (2015) Biomarkers of hypertension and cardiovascular disease. In: Peplow, P., Adams, J. and Young, T. (eds.) Cardiovascular and Metabolic Disease: Scientific Discoveries and New Therapies. Series: RSC Drug discovery series. Royal Society of Chemistry, pp. 117-136. ISBN 9781782620464 (doi: 10.1039/9781782622390-00117)
Welsh, P. , Preiss, D. , Tsiropoulou, S., Rios, F. J. , Harvey, A., Dulak-Lis, M. G., Montezano, A. C. and Touyz, R. M. (2015) Biomarkers of vascular inflammation and cardiovascular disease. In: Berbari, A. and Mancia, G. (eds.) Arterial Disorders: Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches. Springer: Cham, pp. 115-136. ISBN 9783319145556 (doi: 10.1007/978-3-319-14556-3_9)
2014
Price, A. H., Welsh, P. , Weir, C. J., Feinkohl, I., Robertson, C. M., Morling, J. R., McLachlan, S., Strachan, M. W. J., Sattar, N. and Price, J. F. (2014) N-terminal pro-brain natriuretic peptide and risk of cardiovascular events in older patients with type 2 diabetes: the Edinburgh Type 2 Diabetes Study. Diabetologia, 57(12), pp. 2505-2512. (doi: 10.1007/s00125-014-3375-9)
Welsh, P. et al. (2014) Contrasting associations of insulin resistance with diabetes, cardiovascular disease and all-cause mortality in the elderly: PROSPER long-term follow-up. Diabetologia, 57(12), pp. 2513-2520. (doi: 10.1007/s00125-014-3383-9) (PMID:25264116)
Rankin, N. J. , Preiss, D. , Welsh, P. , Burgess, K. E.V., Nelson, S. M. , Lawlor, D. A. and Sattar, N. (2014) The emergence of proton nuclear magnetic resonance metabolomics in the cardiovascular arena as viewed from a clinical perspective. Atherosclerosis, 237(1), pp. 287-300. (doi: 10.1016/j.atherosclerosis.2014.09.024) (PMID:25299963) (PMCID:PMC4232363)
Welsh, P. and Sattar, N. (2014) Vitamin D genes and mortality. British Medical Journal, 349, g6599. (doi: 10.1136/bmj.g6599)
Welsh, P. et al. (2014) Do cardiac biomarkers NT-proBNP and hsTnT predict microvascular events in patients With type 2 diabetes? Results from the ADVANCE Trial. Diabetes Care, 37(8), pp. 2202-2210. (doi: 10.2337/dc13-2625)
Hillis, G. S., Welsh, P. , Chalmers, J., Woodward, M. and Sattar, N. (2014) Response to comment on Hillis et al. The relative and combined ability of high-sensitivity cardiac troponin T and N-Terminal Pro-B-Type natriuretic peptide to predict Cardiovascular Events and Death in Patients With Type 2 Diabetes. Diabetes Care 2014;37:295-303. Diabetes Care, 37(6), e154-e154. (doi: 10.2337/dc14-0485)
Welsh, P. and Sattar, N. (2014) Vitamin D and chronic disease prevention. British Medical Journal, 348, g2280. (doi: 10.1136/bmj.g2280)
Graham, L. A. et al. (2014) Validation of uromodulin as a candidate gene for human essential hypertension. Hypertension, 63(3), pp. 551-558. (doi: 10.1161/HYPERTENSIONAHA.113.01423)
Welsh, P. , Poulter, N. R., Chang, C. L., Sever, P. S. and Sattar, N. (2014) The Value of N-Terminal Pro–B-Type Natriuretic Peptide in Determining Antihypertensive Benefit: Observations From the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). Hypertension, 63(3), pp. 507-513. (doi: 10.1161/HYPERTENSIONAHA.113.02204)
Preiss, D. , Lloyd, S. M. , Ford, I. , McMurray, J. J.V. , Holman, R. R., Welsh, P. , Fisher, M., Packard, C. J. and Sattar, N. (2014) Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial. Lancet Diabetes and Endocrinology, 2(2), pp. 116-124. (doi: 10.1016/S2213-8587(13)70152-9) (PMID:24622715)
Goya Wannamethee, S., Welsh, P. , Whincup, P. H., Lennon, L., Papacosta, O. and Sattar, N. (2014) N-terminal pro brain natriuretic peptide but not copeptin improves prediction of heart failure over other routine clinical risk parameters in older men with and without cardiovascular disease: population-based study. European Journal of Heart Failure, 16(1), pp. 25-32. (doi: 10.1093/eurjhf/hft124)
Hillis, G. S. et al. (2014) The Relative and Combined Ability of High-Sensitivity Cardiac Troponin T and N-Terminal Pro-B-Type Natriuretic Peptide to Predict Cardiovascular Events and Death in Patients With Type 2 Diabetes. Diabetes Care, 37(1), pp. 295-303. (doi: 10.2337/dc13-1165)
Mirjafari, H. et al. (2014) N-terminal pro-brain-type natriuretic peptide (NT-pro-BNP) and mortality risk in early inflammatory polyarthritis: results from the Norfolk Arthritis Registry (NOAR). Annals of the Rheumatic Diseases, 73(4), pp. 684-690. (doi: 10.1136/annrheumdis-2012-202848)
Wannamethee, S. G., Welsh, P. , Papacosta, O., Lennon, L., Whincup, P. H. and Sattar, N. (2014) Elevated parathyroid hormone, but not vitamin D deficiency, is associated with increased risk of heart failure in older men with and without cardiovascular disease. Circulation: Heart Failure, 7(5), pp. 732-739. (doi: 10.1161/CIRCHEARTFAILURE.114.001272)
Welsh, P. , Smith, K. and Nelson, S. M. (2014) A single-centre evaluation of two new anti-Mullerian hormone assays and comparison with the current clinical standard assay. Human Reproduction, 29(5), pp. 1035-1041. (doi: 10.1093/humrep/deu036) (PMID:24578473)
2013
Feinkohl, I. et al. (2013) Clinical and subclinical macrovascular disease as predictors of cognitive decline in older patients with type 2 diabetes: the Edinburgh type 2 diabetes study. Diabetes Care, 36(9), pp. 2779-2786. (doi: 10.2337/dc12-2241)
Sever, P.S., Poulter, N.R., Chang, C.L., Thom, S.A.M., Hughes, A.D., Welsh, P. and Sattar, N. (2013) Evaluation of C-reactive protein before and on-treatment as a predictor of benefit of atorvastatin. Journal of the American College of Cardiology, 62(8), pp. 717-729. (doi: 10.1016/j.jacc.2013.02.098)
Tillin, T., Hughes, A.D., Godsland, I.F., Whincup, P., Forouhi, N.G., Welsh, P. , Sattar, N. , McKeigue, P.M. and Chaturvedi, N. (2013) Insulin resistance and truncal obesity as important determinants of the greater incidence of diabetes in Indian Asians and African Caribbeans compared with Europeans: the Southall and Brent REvisited (SABRE) cohort. Diabetes Care, 36(2), pp. 383-393. (doi: 10.2337/dc12-0544)
Welsh, P. , Doolin, O., Willeit, P., Packard, C. , Macfarlane, P., Cobbe, S., Gudnason, V., Di Angelantonio, E., Ford, I. and Sattar, N. (2013) N-terminal pro-B-type natriuretic peptide and the prediction of primary cardiovascular events: results from 15-year follow-up of WOSCOPS. European Heart Journal, 34(6), pp. 443-450. (doi: 10.1093/eurheartj/ehs239)
Wijsman, L.W., de Craen, A.J.M., Trompet, S., Gussekloo, J., Stott, D.J. , Rodondi, N., Welsh, P. , Jukema, J.W., Westendorp, R.G.J. and Mooijaart, S.P. (2013) Subclinical thyroid dysfunction and cognitive decline in old age. PLoS ONE, 8(3), e59199. (doi: 10.1371/journal.pone.0059199) (PMID:23554996) (PMCID:PMC3595244)
2012
Welsh, P. et al. (2012) Circulating 250HD, dietary vitamin D, PTH, and calcium associations with incident cardiovascular disease and mortality: The MIDSPAN Family Study. Journal of Clinical Endocrinology and Metabolism, 97(12), pp. 4578-4587. (doi: 10.1210/jc.2012-2272)
MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 32(11), pp. 2569-2579. (doi: 10.1161/ATVBAHA.112.251314)
Miller, A. M. et al. (2012) Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? PLoS ONE, 7(10), e47830. (doi: 10.1371/journal.pone.0047830) (PMID:23112853) (PMCID:PMC3480428)
Feinkohl, I., Sattar, N. , Welsh, P. , Reynolds, R. M., Deary, I. J., Strachan, M. W.J. and Price, J. F. (2012) Association of N-terminal pro-brain natriuretic peptide with cognitive function and depression in elderly people with type 2 diabetes. PLoS ONE, 7(9), e44569. (doi: 10.1371/journal.pone.0044569) (PMID:22973461) (PMCID:PMC3433429)
Knox, S. et al. (2012) 25-hydroxyvitamin D is lower in deprived groups, but is not associated with carotid intima media thickness or plaques: results from pSoBid. Atherosclerosis, 223(2), pp. 437-441. (doi: 10.1016/j.atherosclerosis.2012.05.001) (PMID:22632919)
Preiss, D. et al. (2012) Lipid-modifying therapies and risk of pancreatitis: a meta-analysis. JAMA: Journal of the American Medical Association, 308(8), pp. 804-811. (doi: 10.1001/jama.2012.8439)
Sattar, N. , Welsh, P. , Panarelli, M. and Forouhi, N.G. (2012) Vitamin D testing – authors' reply. Lancet, 379(9827), pp. 1700-1701. (doi: 10.1016/S0140-6736(12)60713-2)
Welsh, P. and McMurray, J.J. (2012) B-type natriuretic peptide and glycaemia: an emerging cardiometabolic pathway? Diabetologia, 55(5), pp. 1240-1243. (doi: 10.1007/s00125-012-2515-3)
Carty, D.M., Anderson, L.A., Freeman, D.J. , Welsh, P.I. , Brennand, J.E., Dominiczak, A.F. and Delles, C. (2012) Early pregnancy soluble E-selectin concentrations and risk of preeclampsia. Journal of Hypertension, 30(5), pp. 954-959. (doi: 10.1097/HJH.0b013e328352573b)
Nanchen, D. et al. (2012) Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. Journal of Clinical Endocrinology and Metabolism, 97(3), pp. 852-861. (doi: 10.1210/jc.2011-1978)
Sever, P. S., Poulter, N. R., Chang, C. L., Hingorani, A., Thom, S. A., Hughes, A. D., Welsh, P. and Sattar, N. (2012) Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial. European Heart Journal, 33(4), pp. 486-494. (doi: 10.1093/eurheartj/ehr262)
Sattar, N. , Welsh, P. , Panarelli, M. and Forouhi, N. G. . (2012) Increasing requests for vitamin D measurement: costly, confusing, and without credibility. Lancet, 379(9811), pp. 95-96. (doi: 10.1016/S0140-6736(11)61816-3)
Goldenberg, D., Miller, E., Perna, M., Sattar, N. , Welsh, P. , Roman, M. J. and Salmon, J. E. (2012) Association of N-terminal pro-brain natriuretic peptide with cardiac disease, but not with vascular disease, in systemic lupus erythematosus. Arthritis and Rheumatism, 64(1), pp. 316-317. (doi: 10.1002/art.33374)
Whiteley, W., Wardlaw, J., Dennis, M., Lowe, G., Rumley, A., Sattar, N. , Welsh, P. , Green, A., Andrews, M. and Sandercock, P. (2012) The use of blood biomarkers to predict poor outcome after acute transient ischemic attack or ischemic stroke. Stroke, 43(1), pp. 86-91. (doi: 10.1161/STROKEAHA.111.634089)
2011
Pfister, R. et al. (2011) Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies. PLoS Medicine, 8(10), e1001112. (doi: 10.1371/journal.pmed.1001112)
Welsh, P. et al. (2011) Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(10), pp. 2338-2344. (doi: 10.1161/ATVBAHA.111.231795) (PMID:21757655)
Mooijaart, S.P. et al. (2011) C-Reactive protein and genetic variants and cognitive decline in old age: the PROSPER Study. PLoS ONE, 6(9), e23890. (doi: 10.1371/journal.pone.0023890) (PMID:21915265) (PMCID:PMC3168438)
Jefferis, B.J., Whincup, P.H., Welsh, P. , Wannathamee, S.G., Rumley, A., Lawlor, D.A., Ebrahim, S. and Lowe, G.D.O. (2011) Prospective study of circulating soluble CD40 ligand concentrations and the incidence of cardiovascular disease in a nested prospective case-control study of older men and women. Journal of Thrombosis and Haemostasis, 9(8), pp. 1452-1459. (doi: 10.1111/j.1538-7836.2011.04415.x)
Wannamethee, S. G., Welsh, P. , Lowe, G. D., Gudnason, V., Di Angelantonio, E., Lennon, L., Rumley, A., Whincup, P. H. and Sattar, N. (2011) N-terminal pro-brain natriuretic peptide is a more useful predictor of cardiovascular disease risk than C-reactive protein in older men with and without pre-existing cardiovascular disease. Journal of the American College of Cardiology, 58(1), pp. 56-64. (doi: 10.1016/j.jacc.2011.02.041)
Welsh, P. et al. (2011) Vitamin D deficiency is common in patients with RA and linked to disease activity, but circulating levels are unaffected by TNF blockade: results from a prospective cohort study. Annals of the Rheumatic Diseases, 70(6), pp. 1165-1167. (doi: 10.1136/ard.2010.137265) (PMID:21047908)
Logue, J. , Murray, H.M., Welsh, P. , Shepherd, J., Packard, C. , Macfarlane, P., Cobbe, S., Ford, I. and Sattar, N. (2011) Obesity is associated with fatal coronary heart disease independently of traditional risk factors and deprivation. Heart, 97(7), pp. 564-568. (doi: 10.1136/hrt.2010.211201)
Wannamethee, S.G., Welsh, P. , Whincup, P.H., Sawar, N., Thomas, M.C., Gudnarsson, V. and Sattar, N. (2011) High adiponectin and increased risk of cardiovascular disease and mortality in asymptomatic older men: does NT-proBNP help to explain this association? European Journal of Cardiovascular Prevention and Rehabilitation, 18(1), pp. 65-71. (doi: 10.1097/HJR.0b013e32833b09d9)
Asquith, D.L., Miller, A.M., Reilly, J.H., Kerr, S., Welsh, P. , Sattar, N. and McInnes, I.B. (2011) Simultaneous activation of the liver X receptors (LXR and LXR) drives murine collagen-induced arthritis disease pathology. Annals of the Rheumatic Diseases, 70(12), pp. 2225-2228. (doi: 10.1136/ard.2011.152652) (PMID:21859686.)
Jefferis, B.J.M.H. et al. (2011) Interleukin 18 and coronary heart disease: Prospective study and systematic review. Atherosclerosis, 217(1), pp. 227-233. (doi: 10.1016/j.atherosclerosis.2011.03.015)
Preiss, D. et al. (2011) Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis. JAMA: Journal of the American Medical Association, 305(24), pp. 2556-2564. (doi: 10.1001/jama.2011.860)
Welsh, P. , Peters, M.J.L. and Sattar, N. (2011) Is vitamin D in rheumatoid arthritis a magic bullet or a mirage? The need to improve the evidence base prior to calls for supplementation. Arthritis and Rheumatism, 63(7), pp. 1763-1769. (doi: 10.1002/art.30341)
Welsh, P. , Peters, M.J.L. and Sattar, N. (2011) Vitamin D insufficiency. New England Journal of Medicine, 364(14), pp. 1378-1379.
Whiteley, W. et al. (2011) Blood biomarkers for the diagnosis of acute cerebrovascular diseases: a prospective cohort study. Cerebrovascular Diseases, 32(2), pp. 141-147. (doi: 10.1159/000328517)
2010
Peters, M. J. L., Watt, P., Cherry, L., Welsh, P. , Henninger, E., Dijkmans, B. A. C., McInnes, I. B. , Nurmohamed, M. T. and Sattar, N. (2010) Lack of effect of TNFα blockade therapy on circulating adiponectin levels in patients with autoimmune disease: results from two independent prospective studies. Annals of the Rheumatic Diseases, 69(9), pp. 1687-1690. (doi: 10.1136/ard.2009.114207) (PMID:19640853)
Peters, M. J. L., Welsh, P. , McInnes, I. B. , Wolbink, G., Dijkmans, B. A. C., Sattar, N. and Nurmohamed, M. T. (2010) Tumour necrosis factor α blockade reduces circulating N-terminal pro-brain natriuretic peptide levels in patients with active rheumatoid arthritis: results from a prospective cohort study. Annals of the Rheumatic Diseases, 69(7), pp. 1281-1285. (doi: 10.1136/ard.2009.119412) (PMID:19934107)
Sattar, N. et al. (2010) Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet, 375(9716), pp. 735-742. (doi: 10.1016/S0140-6736(09)61965-6)
Welsh, P. et al. (2010) Unraveling the directional link between adiposity and inflammation: a bidirectional mendelian randomization approach. Journal of Clinical Endocrinology and Metabolism, 95(1), pp. 93-99. (doi: 10.1210/jc.2009-1064)
Jefferis, B. J. et al. (2010) Secondhand smoke (SHS) exposure is associated with circulating markers of inflammation and endothelial function in adult men and women. Atherosclerosis, 208(2), pp. 550-556. (doi: 10.1016/j.atherosclerosis.2009.07.044)
Jefferis, B. J. et al. (2010) Prospective study of matrix metalloproteinase-9 and risk of myocardial infarction and stroke in older men and women. Atherosclerosis, 208(2), pp. 557-563. (doi: 10.1016/j.atherosclerosis.2009.08.018)
Padmanabhan, S. et al. (2010) Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genetics, 6(10), e1001177. (doi: 10.1371/journal.pgen.1001177)
Preiss, D. , Welsh, P. , Murray, H., Shepherd, J., Packard, C. , Macfarlane, P., Cobbe, S., Ford, I. and Sattar, N. (2010) Fasting plasma glucose in non-diabetic participants and the risk for incident cardiovascular events, diabetes, and mortality: results from WOSCOPS 15-year follow-up(dagger). European Heart Journal, 31(10), pp. 1230-1236. (doi: 10.1093/eurheartj/ehq095)
Sattar, N. , Preiss, D. , Welsh, P. , Seshasai, S.R.K. and Ray, K.K. (2010) Statins and risk of incident diabetes Reply. Lancet, 375(9732), pp. 2141-2142.
Sattar, N. , Welsh, P. , Sarwar, N., Danesh, J., Di Angelantonio, E., Gudnason, V., Smith, G. D., Ebrahim, S. and Lawlor, D. A. (2010) NT-proBNP is associated with coronary heart disease risk in healthy older women but fails to enhance prediction beyond established risk factors: Results from the British Women's Heart and Health Study. Atherosclerosis, 209(1), pp. 295-299. (doi: 10.1016/j.atherosclerosis.2009.09.016)
Stott, D.J. et al. (2010) Activation of Hemostasis and Decline in Cognitive Function in Older People. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(3), pp. 605-611. (doi: 10.1161/ATVBAHA.109.199448)
Talwar, D., McConnachie, A. , Welsh, P. , Upton, M., O'Reilly, D., Davey Smith, G., Watt, G. and Sattar, N. (2010) Which circulating antioxidant vitamins are confounded by socioeconomic deprivation? The MIDSPAN family study. PLoS ONE, 5(6), e11312. (doi: 10.1371/journal.pone.0011312) (PMID:20593021) (PMCID:PMC2892487)
Welsh, P. , Woodward, M., Rumley, A., MacMahon, S. and Lowe, G.D. (2010) Does interleukin-18 or tumour necrosis factor-alpha have an independent association with the risk of coronary heart disease? Results from a prospective study in New Zealand. Cytokine, 50(1), pp. 94-98. (doi: 10.1016/j.cyto.2009.12.014)
Woodward, M., Welsh, P. , Rumley, A., Tunstall-Pedoe, H. and Lowe, G. D. O. (2010) Do inflammatory biomarkers add to the discrimination of cardiovascular disease after allowing for social deprivation? Results from a 10-year cohort study in Glasgow, Scotland. European Heart Journal, 31(21), pp. 2669-2675. (doi: 10.1093/eurheartj/ehp115)
2009
Stott, D.J., Welsh, P.I., Rumley, A., Robertson, M., Ford, I. , Sattar, N.A., Westendorp, R.G.J., Jukema, J.W., Cobbe, S. and Lowe, G.D. (2009) Adipocytokines and risk of stroke in older people: a nested case-control study. International Journal of Epidemiology, 38(1), pp. 253-261. (doi: 10.1093/ije/dyn215)
Welsh, P. et al. (2009) Leptin Predicts Diabetes but Not Cardiovascular Disease Results from a large prospective study in an elderly population. Diabetes Care, 32(2), pp. 308-310. (doi: 10.2337/dc08-1458)
Ang, D., Welsh, P. , Watt, P., Nelson, S. , Struthers, A. and Sattar, N. (2009) Serial changes in adiponectin and BNP in ACS patients: paradoxical associations with each other and with prognosis. Clinical Science, 117(1-2), pp. 41-48.
Jefferis, B. et al. (2009) Circulating TNF alpha levels in older men and women do not show independent prospective relations with MI or stroke. Atherosclerosis, 205(1), pp. 302-308.
Sattar, N.A. et al. (2009) Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Medicine, 6(6), e1000099. (doi: 10.1371/journal.pmed.1000099)
Sattar, N. et al. (2009) Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia, 52(2), pp. 235-239.
Welsh, P., Barber, M., Langhorne, P., Rumley, A., Lowe, G. and Stott, D. (2009) Associations of Inflammatory and Haemostatic Biomarkers with Poor Outcome in Acute Ischaemic Stroke. Cerebrovascular Diseases, 27(3), pp. 247-253. (doi: 10.1159/000196823)
Welsh, P., Woodward, M., Rumley, A. and Lowe, G.D. (2009) Associations of circulating TNF alpha and IL-18 with myocardial infarction and cardiovascular risk markers: The Glasgow Myocardial Infarction Study. Cytokine, 47(2), pp. 143-147.
2008
Welsh, P. , Lowe, G.D., Chalmers, J., Campbell, D., Rumley, A., Neal, B.C., MacMahon, S.W. and Woodward, M. (2008) Associations of proinflammatory cytokines with the risk of recurrent stroke. Stroke, 39(8), pp. 2226-2230. (doi: 10.1161/STROKEAHA.107.504498)
Welsh, P.I. , Whincup, P.H., Papacosta, O., Wannamethee, S.G., Lennon, L., Thomson, A.H., Thomson, A.J., Rumley, A. and Lowe, G.D. (2008) Serum matrix metalloproteinase-9 and coronary heart disease: a prospective study in middle-aged men. QJM: An International Journal of Medicine, 101(10), pp. 785-791.
Welsh, P. , Packard, C. and Sattar, N. (2008) Novel antecedent plasma biomarkers of cardiovascular disease: improved evaluation methods and comparator benchmarks raise the bar. Current Opinion in Lipidology, 19(6), pp. 563-571.
Welsh, P. , Woodward, M. and Lowe, G. (2008) Associations of plasma pro-inflammatory cytokines, fibrinogen, viscosity and C-reactive protein with cardiovascular risk factors and social deprivation: the fourth Glasgow MONICA study. British Journal of Haematology, 141(6), pp. 852-861.
Articles
Anderson, J. J., Deo, S. V. , Welsh, P. , Mackay, D. F. , Ho, F. K., Ferguson, L. D. , Celis-Morales, C. , Gill, J.R. , Pell, J. P. and Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949) (Early Online Publication)
Xiong, X. et al. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (Accepted for Publication)
Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901) (PMID:39217504) (Early Online Publication)
Liu, Q., Celis-Morales, C. , Sattar, N. and Welsh, P. (2024) Association of glycaemic control with intraocular pressure in a large general population: Results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865) (Early Online Publication)
Liu, Q., Celis-Morales, C. , Sattar, N. and Welsh, P. (2024) Association of glycemic control with intraocular pressure in a large general population: results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865) (PMID:39157858) (Early Online Publication)
Carberry, J. et al. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure, 11(4), pp. 2001-2012. (doi: 10.1002/ehf2.14830) (PMID:38715187) (PMCID:PMC11287338)
Churuangsuk, C., Catchpole, A., Talwar, D., Welsh, P. , Sattar, N. , Combet Aspray, E. and Lean, M. E.J. (2024) Low thiamine status in adults following low-carbohydrate / ketogenic diets: a cross-sectional comparative study of micronutrient intake and status. European Journal of Nutrition, (doi: 10.1007/s00394-024-03459-y) (PMID:38967675) (Early Online Publication)
Curtain, J. P. et al. (2024) Measuring congestion with a non-invasive monitoring device in heart failure and haemodialysis: CONGEST-HF. European Journal of Heart Failure, 26(6), pp. 1383-1392. (doi: 10.1002/ejhf.3290) (PMID:38741283)
Al-Abdullah, L., Ahern, A., Welsh, P. and Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, (Accepted for Publication)
Hillary, R. F. et al. (2024) Blood-based epigenome-wide analyses of chronic low-grade inflammation across diverse population cohorts. Cell Genomics, 4(5), 100544. (doi: 10.1016/j.xgen.2024.100544) (PMID:38692281) (PMCID:PMC11099341)
Lean, M. E.J. et al. (2024) 5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension study. Lancet Diabetes and Endocrinology, 12(4), pp. 233-246. (doi: 10.1016/S2213-8587(23)00385-6) (PMID:38423026)
Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, 32. (doi: 10.1038/s43856-024-00455-5) (PMID:38418616) (PMCID:PMC10901805)
Bull, C. J. et al. (2024) Impact of weight loss on cancer-related proteins in serum: results from a cluster randomised controlled trial of individuals with type 2 diabetes. EBioMedicine, 100, 104977. (doi: 10.1016/j.ebiom.2024.104977) (PMID:38290287) (PMCID:PMC10844806)
Chybowska, A. D. et al. (2024) Epigenetic contributions to clinical risk prediction of cardiovascular disease. Circulation: Genomic and Precision Medicine, 17(1), e004265. (doi: 10.1161/CIRCGEN.123.004265) (PMID:38288591)
Welsh, P. et al. (2024) Elevated lipoprotein(a) increases risk of subsequent major adverse cardiovascular events (MACE) and coronary revascularisation in incident ASCVD patients: a cohort study from the UK biobank. Atherosclerosis, 389, 117437. (doi: 10.1016/j.atherosclerosis.2023.117437) (PMID:38219651)
Corbin, L. J. et al. (2024) The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT). Diabetologia, 67(1), pp. 74-87. (doi: 10.1007/s00125-023-06019-x) (PMID:37878066) (PMCID:PMC10709482)
Sofianopoulou, E. et al. (2024) Estimating dose—response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and revised Mendelian randomization analyses. Lancet Diabetes and Endocrinology, 12(1), E2-E11. (doi: 10.1016/S2213-8587(23)00287-5) (PMID:38048800)
Welsh, P. et al. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study. Clinical Chemistry, 70(2), pp. 403-413. (doi: 10.1093/clinchem/hvad205) (PMID:38069915)
Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7(4), pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)
Goudswaard, L. J. et al. (2023) Using trials of caloric restriction and bariatric surgery to explore the effects of body mass index on the circulating proteome. Scientific Reports, 13, 21077. (doi: 10.1038/s41598-023-47030-x) (PMID:38030643) (PMCID:PMC10686974)
McDowell, K., Adamson, C., Jackson, C., Campbell, R., Welsh, P. , Petrie, M. C. , McMurray, J. J.V. , Jhund, P. and Herring, N. (2023) Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes. European Journal of Heart Failure, (doi: 10.1002/ejhf.3085) (PMID:37937329) (Early Online Publication)
Sattar, N. et al. (2023) Prediction of cardiometabolic health through changes in plasma proteins with intentional weight loss in the DiRECT and DIADEM-I randomised clinical trials of type 2 diabetes remission. Diabetes Care, 46(11), pp. 1949-1957. (doi: 10.2337/dc23-0602) (PMID:37756566) (PMCID:PMC10628468)
Al Ozairi, E. et al. (2023) The effect of home-based resistance exercise training in people with type 2 diabetes: a randomized controlled trial. Diabetes/Metabolism Research and Reviews, 39(7), e3677. (doi: 10.1002/dmrr.3677) (PMID:37330638)
Boonpor, J. et al. (2023) Associations and predictive performance of eleven anthropometric measures with incident type 2 diabetes: a prospective cohort study from the UK Biobank. Obesity, 31(10), pp. 2648-2657. (doi: 10.1002/oby.23849) (PMID:37724055)
Logan, G. , Somers, C., Baker, G., Connell, H., Gray, S. , Kelly, P., McIntosh, E. , Welsh, P. , Gray, C. and Gill, J. M. (2023) Benefits, risks, barriers, and facilitators to cycling: a narrative review. Frontiers in Sports and Active Living, 5, 1168357. (doi: 10.3389/fspor.2023.1168357) (PMID:37795314) (PMCID:PMC10546027)
Yeoh, S. E. et al. (2023) Dapagliflozin versus metolazone in heart failure resistant to loop diuretics. European Heart Journal, 44(31), pp. 2966-2977. (doi: 10.1093/eurheartj/ehad341) (PMID:37210742)
Karusheva, Y. et al. (2023) Association of GDF15 levels with body mass index and endocrine status in β-thalassaemia. Clinical Endocrinology, 99(2), pp. 182-189. (doi: 10.1111/cen.14897) (PMID:36806122)
Zhou, Z., Parra-Soto, S., Boonpor, J., Petermann-Rocha, F., Welsh, P. , Mark, P. B. , Sattar, N. , Pell, J. P. , Celis-Morales, C. and Ho, F. K. (2023) Exploring the underlying mechanisms linking adiposity and cardiovascular disease: a prospective cohort study of 404,332 UK Biobank participants. Current Problems in Cardiology, 48(8), 101715. (doi: 10.1016/j.cpcardiol.2023.101715) (PMID:37004891)
Docherty, K. F. et al. (2023) Association of carbohydrate antigen 125 on the response to dapagliflozin in patients with heart failure. Journal of the American College of Cardiology, 82(2), pp. 142-157. (doi: 10.1016/j.jacc.2023.05.011) (PMID:37407113)
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Welsh, P. , Woodward, M., Rumley, A., MacMahon, S. and Lowe, G.D. (2010) Does interleukin-18 or tumour necrosis factor-alpha have an independent association with the risk of coronary heart disease? Results from a prospective study in New Zealand. Cytokine, 50(1), pp. 94-98. (doi: 10.1016/j.cyto.2009.12.014)
Woodward, M., Welsh, P. , Rumley, A., Tunstall-Pedoe, H. and Lowe, G. D. O. (2010) Do inflammatory biomarkers add to the discrimination of cardiovascular disease after allowing for social deprivation? Results from a 10-year cohort study in Glasgow, Scotland. European Heart Journal, 31(21), pp. 2669-2675. (doi: 10.1093/eurheartj/ehp115)
Stott, D.J., Welsh, P.I., Rumley, A., Robertson, M., Ford, I. , Sattar, N.A., Westendorp, R.G.J., Jukema, J.W., Cobbe, S. and Lowe, G.D. (2009) Adipocytokines and risk of stroke in older people: a nested case-control study. International Journal of Epidemiology, 38(1), pp. 253-261. (doi: 10.1093/ije/dyn215)
Welsh, P. et al. (2009) Leptin Predicts Diabetes but Not Cardiovascular Disease Results from a large prospective study in an elderly population. Diabetes Care, 32(2), pp. 308-310. (doi: 10.2337/dc08-1458)
Ang, D., Welsh, P. , Watt, P., Nelson, S. , Struthers, A. and Sattar, N. (2009) Serial changes in adiponectin and BNP in ACS patients: paradoxical associations with each other and with prognosis. Clinical Science, 117(1-2), pp. 41-48.
Jefferis, B. et al. (2009) Circulating TNF alpha levels in older men and women do not show independent prospective relations with MI or stroke. Atherosclerosis, 205(1), pp. 302-308.
Sattar, N.A. et al. (2009) Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? PLoS Medicine, 6(6), e1000099. (doi: 10.1371/journal.pmed.1000099)
Sattar, N. et al. (2009) Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia, 52(2), pp. 235-239.
Welsh, P., Barber, M., Langhorne, P., Rumley, A., Lowe, G. and Stott, D. (2009) Associations of Inflammatory and Haemostatic Biomarkers with Poor Outcome in Acute Ischaemic Stroke. Cerebrovascular Diseases, 27(3), pp. 247-253. (doi: 10.1159/000196823)
Welsh, P., Woodward, M., Rumley, A. and Lowe, G.D. (2009) Associations of circulating TNF alpha and IL-18 with myocardial infarction and cardiovascular risk markers: The Glasgow Myocardial Infarction Study. Cytokine, 47(2), pp. 143-147.
Welsh, P. , Lowe, G.D., Chalmers, J., Campbell, D., Rumley, A., Neal, B.C., MacMahon, S.W. and Woodward, M. (2008) Associations of proinflammatory cytokines with the risk of recurrent stroke. Stroke, 39(8), pp. 2226-2230. (doi: 10.1161/STROKEAHA.107.504498)
Welsh, P.I. , Whincup, P.H., Papacosta, O., Wannamethee, S.G., Lennon, L., Thomson, A.H., Thomson, A.J., Rumley, A. and Lowe, G.D. (2008) Serum matrix metalloproteinase-9 and coronary heart disease: a prospective study in middle-aged men. QJM: An International Journal of Medicine, 101(10), pp. 785-791.
Welsh, P. , Packard, C. and Sattar, N. (2008) Novel antecedent plasma biomarkers of cardiovascular disease: improved evaluation methods and comparator benchmarks raise the bar. Current Opinion in Lipidology, 19(6), pp. 563-571.
Welsh, P. , Woodward, M. and Lowe, G. (2008) Associations of plasma pro-inflammatory cytokines, fibrinogen, viscosity and C-reactive protein with cardiovascular risk factors and social deprivation: the fourth Glasgow MONICA study. British Journal of Haematology, 141(6), pp. 852-861.
Book Sections
Welsh, P. and Iliodromiti, S. (2019) Epidemiology of vascular diseases. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 299-306. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_28)
Sattar, N. , Welsh, P. and Preiss, D. (2015) The insulin resistance syndrome. In: DeFronzo, R. A., Ferrannini, E., Alberti, K.G.M.M. and Zimmet, P. (eds.) International Textbook of Diabetes Mellitus. John Wiley & Sons, Ltd, pp. 337-353. ISBN 9781118387658 (doi: 10.1002/9781118387658.ch23)
Welsh, P. , Preiss, D. and Touyz, R. M. (2015) Biomarkers of hypertension and cardiovascular disease. In: Peplow, P., Adams, J. and Young, T. (eds.) Cardiovascular and Metabolic Disease: Scientific Discoveries and New Therapies. Series: RSC Drug discovery series. Royal Society of Chemistry, pp. 117-136. ISBN 9781782620464 (doi: 10.1039/9781782622390-00117)
Welsh, P. , Preiss, D. , Tsiropoulou, S., Rios, F. J. , Harvey, A., Dulak-Lis, M. G., Montezano, A. C. and Touyz, R. M. (2015) Biomarkers of vascular inflammation and cardiovascular disease. In: Berbari, A. and Mancia, G. (eds.) Arterial Disorders: Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches. Springer: Cham, pp. 115-136. ISBN 9783319145556 (doi: 10.1007/978-3-319-14556-3_9)
Conference or Workshop Item
Paterson, C., Hinterberg, M. A., Morrow, A. J. , Sykes, R. , Mangion, K., Welsh, P. , McConnachie, A. , Sattar, N. , Berry, C. and Williams, S. A. (2022) Utility of a Proteomic Surrogate for Cardiovascular Outcomes to Predict and Monitor COVID-19 Induced Myocarditis. American Heart Association's 2022 Scientific Sessions and the American Heart Association's 2022 Resuscitation Science Symposium, Chicago, Illinois, USA, 04-07 Nov 2022. (doi: 10.1161/circ.146.suppl_1.12132)
Mangion, K. et al. (2022) Multi-system investigation of COVID-19 illness. British Cardiovascular Society Annual Conference, ‘100 years of Cardiology’, Manchester, UK, 06-08 June 2022. A122.1-A122. (doi: 10.1136/heartjnl-2022-BCS.157)
Morrow, A. et al. (2021) Rationale and design of the Medical Research Council Precision medicine with Zibotentan in microvascular angina (PRIZE) trial MRI sub-study. British Society of Cardiovascular Magnetic Resonance 2021 Annual Meeting, 12 October 2021. A2.1-A2. (doi: 10.1136/heartjnl-2021-BSCMR.3)
Conference Proceedings
Ferguson, L. , Welsh, P. , Brown, R., Tindell, A., Kerrigan, S., Sattar, N. , McInnes, I. and Siebert, S. (2019) Effect of Phosphodiesterase 4 Inhibition with Apremilast on Cardiometabolic Outcomes in Psoriatic Arthritis – Initial Results from the Immune Metabolic Associations in Psoriatic Arthritis (IMAPA) Study. In: 2019 ACR/ARP Annual Meeting, Atlanta, GA, 8-13 November 2019,
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Optimising Atrial Fibrillation Screening to Prevent Recurrent Ischaemic Stroke (OASIS)
Stroke Association
2024 - 2027
- Seasonal variation in cardiovascular hospitalisations in the UK Biobank cohort
Tenovus Scotland
2024 - 2024
- Angina after PCI: a systems approach to inform downstream strategies
British Heart Foundation
2024 - 2029
- Characterisation of Cardiovascular Function in ICU Survivors of Sepsis
Wellcome Trust
2023 - 2023
- AF Screening to Prevent Ischaemic StRokE (The ASPIRE Study) - The Role of Blood, ECG and Genetic Biomarkers
Stroke Association
2023 - 2025
- PHOSP-COVID Post-hospitalisation COVID-19 study: a national consortium to understand and improve long-term health outcomes
Medical Research Council
2022 - 2023
- A randomised placebo-controlled trial of fenofibrate to prevent progression of non-proliferative retinopathy in diabetes (LENS: Lowering Events in Non-proliferative retinopathy in Scotland)
National Institute for Health Research
2022 - 2024
- Biobank
Scottish Government
2022 - 2022
- Dietary Patterns, nutritional status, frailty and the development of disability: defining pathways and optimising prevention
Dunhill Medical Trust
2018 - 2018
- Associations of blood biomarkers with cardiovascular disease and related cardiometabolic outcomes and risk prediction in the clinical setting: UK biobank
Chest Heart and Stroke Scotland
2016 - 2018
- In-silico quantification of metabolites, lipids and lipoproteins measured by NMR spectroscopy
Wellcome Trust
2016 - 2017
- Cardiac biomarkers and the prediction of CVD in Scotland
Chief Scientist Office
2015 - 2018
- British Regional Heart Study (BRHS): a long-term prospective investigation of cardiovascular disease (causes, pathways, prediction and prevention) among older British men.
British Heart Foundation
2014 - 2019
- Understanding the associations of physical activity and sedentary behaviours on established and novel markers of cardiovascular risk in older age
British Heart Foundation
2014 - 2015
- Southall blood sample analysis collaboration - UCL
NHS Greater Glasgow and Clyde Endowment Funds
2014 - 2018
- Explaining excess winter mortality from CHD: analysis of UK based prospective studies
British Heart Foundation
2014 - 2016
- The UPBEAT RCT mother-child study. Stratifying and treating obese pregnant women to prevent adverse pregnancy, perinatal and longer term outcomes
Medical Research Council
2014 - 2017
- The effect of metformin therapy on NT-proBNP levels in non-diabetic patients with established coronary heart disease
NHS Greater Glasgow and Clyde
2013 - 2014
- Assessing the predictive value of quantitative high-throughput NMR metabolomic analysis for CVD events in a major study of diabetes: ADVANCE
Chest Heart and Stroke Scotland
2013 - 2016
- Cardiac biomarkers and CVD risk screening: a cost-effective public health measure?
British Heart Foundation
2013 - 2016
- EMIF
European Commission
2013 - 2017
- Analysis of bloods samples in the Pakistan Risk of Myocardial Infarction Study (PROMIS)
NHS Greater Glasgow and Clyde Endowment Funds
2012 - 2014
- Testing novel predictors of atherosclerosis progression in the relationship between insulin sensitivity and Cardiovascular disease (RISC) study
NHS Greater Glasgow and Clyde
2011 - 2012
- Vitamin D as a (causal) determinant of insulin resistance and diabetes? An analysis of three UK based prospective studies
Diabetes UK
2010 - 2013
- Vitamin D levels and intake and cardiovascular events in the West of Scotland? A 14-year follow up of the MIDSPAN family study
Chest Heart and Stroke Scotland
2010 - 2011
- NT-proBNP as a predictor of vascular events in WOSCOPS: using modern epidemiological techniques to test clinical utility of a biomarker
British Heart Foundation
2010 - 2012
Supervision
- AHMAD, AL MALEK HUSSIEN BIN
MSc in Cardiovascular Sciences as the masters taught component of the iPhD - Hayman, Madeleine
Does severe mental illness predispose to cardiovascular and metabolic disease via an unfavourable adipose storage profile? - Liu, Qiaoling
Physical Activity and Its Association with CVD - Ralston, Maximilian
See research proposal (more than 70 characters) - Rochmawati, Ike Dhiah
Risk Stratification for Very High Cardiovascular Risk: Refining Risk Scoring with Incorporates Lipid Profile and Other Markers