Diabetes & Endocrinology
Our aim is to understand more fully the mechanisms underpinning links between metabolic, endocrine and cardiovascular diseases, and their implications for the wider population and subgroups of interest.
Staff
Publications
2024
Nakada, S., Welsh, P., Celis-Morales, C., Pell, J. P., Ho, F. K. (2024) Predictive values of depression and anxiety disorder over the PREVENT predictors: development of prediction models for 10-year risk of cardiovascular disease. Canadian Medical Association Journal,
Greenlees, C., Hosseinzadeh, S., Delles, C., Mcginnigle, E. (2024) Hypertension evaluation and management in new young patients: are we doing our female patients a disservice? Blood Pressure, 33, (doi: 10.1080/08037051.2024.2387909)
De Biase, N., Del Punta, L., L'Hoyes, W., Pellicori, P., Cleland, J. G.F., Masini, G., Gargani, L., Moura-Ferreira, S., Hoedemakers, S., Di Fiore, V., Herbots, L., Stassen, J., Mengozzi, A., Armenia, S., Taddei, S., Masi, S., Verwerft, J., Pugliese, N. R. (2024) Associations of iron deficiency with cardiac function, congestion, exercise capacity and prognosis in heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.3534)
Badve, S. V., Bilal, A., Lee, M. M. Y., Sattar, N., Gerstein, H. C., Ruff, C. T., McMurray, J. J. V., Rossing, P., Bakris, G., Mahaffey, K. W., Mann, J. F. E., Colhoun, H. M., Tuttle, K. R., Pratley, R. E., Perkovic, V. (2024) Effects of GLP-1 receptor agonists on kidney and cardiovascular disease outcomes: a meta-analysis of randomised controlled trials. Lancet Diabetes and Endocrinology, (doi: 10.1016/S2213-8587(24)00271-7)
McGinley, K. A., Lucas-Herald, A., Connelly, P., Delles, C. (2024) Gender-affirming hormone therapy: effects on cardiovascular risk and vascular function. Endocrine Connections, (doi: 10.1530/EC-24-0222)
Delles, C., Schmieder, R. E., Daly, R., Kannenkeril, D., Bosch, A., Lauder, L., Kunz, M., Böhm, M., Hamilton, G., Schmieder, R. S., Schmid, A., Herzyk, P., Mahfoud, F. (2024) Response of blood pressure to renal denervation is not associated with genetic variants. Hypertension, (doi: 10.1161/HYPERTENSIONAHA.124.23393)
Monzo, L., Bresso, E., Dickstein, K., Pitt, B., Cleland, J. G.F., Anker, S. D., Lam, C. S.P., Mehra, M. R., van Veldhuisen, D. J., Greenberg, B., Zannad, F., Girerd, N. (2024) Machine learning approach to identify phenotypes in patients with ischemic heart failure with reduced ejection fraction. European Journal of Heart Failure,
Seckin, M., Petrie, M. C., Stewart, S., Johnston, B. M. (2024) A descriptive qualitative study of breathlessness and its management of Turkish individuals with self-reported heart failure. BMJ Open, 14, (doi: 10.1136/ bmjopen-2024-088335)
Ho, F. K., Mark, P. B., Lees, J. S., Pell, J. P., Strawbridge, R. J., Kimenai, D. M., Mills, N. L., Woodward, M., McMurray, J. J.V., Sattar, N., Welsh, P. (2024) A proteomics-based approach for prediction of different cardiovascular diseases and dementia. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.070454)
Krentz, A., Jacob, S., Heiss, C., Sattar, N., Lim, S., Khunti, K., Eckel, R. H. (2024) Corrigendum to “Rising to the challenge of cardio-renal-metabolic disease in the 21st century: Translating evidence into best clinical practice to prevent and manage atherosclerosis” [Atherosclerosis, Vol 396, (September 2024), 118528] Atherosclerosis, 398, pp. 118610. (doi: 10.1016/j.atherosclerosis.2024.118610)
Osmanska, J., Petrie, M. C., Docherty, K. F., Lee, M. M.Y., McMurray, J. J.V., Campbell, R. (2024) Subcutaneous furosemide in heart failure: a systematic review. European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae083)
Averbuch, T., Lee, S. F., Zagorski, B., Pandey, A., Petrie, M. C., Biering‐Sorensen, T., Xie, F., Van Spall, H. G.C. (2024) Long‐term clinical outcomes and healthcare resource utilization in male and female patients following hospitalization for heart failure. European Journal of Heart Failure, (doi: 10.1002/ejhf.3499)
Fletcher, R. A. et al. (2024) Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. Lancet Public Health, 9, pp. e871-e885. (doi: 10.1016/S2468-2667(24)00215-9)
Rochmawati, I. D., Deo, S., Lees, J. S., Mark, P. B., Sattar, N., Celis-Morales, C., Pell, J. P., Welsh, P., Ho, F. K. (2024) Adding traditional and emerging biomarkers for risk assessment in secondary prevention: a prospective cohort study of 20,656 patients with cardiovascular disease. European Journal of Preventive Cardiology, (doi: 10.1093/eurjpc/zwae352)
Xiong, X., Lui, D. T.W., Ju, C., Zhou, Z., Xu, C., Welsh, P., Sattar, N., Celis-Morales, C., Pell, J. P., Wong, I. C.K., Wong, C. K.H., Ho, F. (2024) Associations of serum lipid traits with fracture and osteoporosis: a prospective cohort study from the UK Biobank. Journal of Cachexia, Sarcopenia and Muscle, (doi: 10.1002/jcsm.13611)
Stamatakis, E., Ahmadi, M., Biswas, R. K., Del Pozo Cruz, B., Thøgersen-Ntoumani, C., Murphy, M. H., Sabag, A., Lear, S., Chow, C., Gill, J. M.R., Hamer, M. (2024) Device-measured vigorous intermittent lifestyle physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences. British Journal of Sports Medicine, (doi: 10.1136/bjsports-2024-108484)
Dieden, A., Girerd, N., Ottosson, F., Molvin, J., Pareek, M., Melander, O., Bachus, E., Råstam, L., Lindblad, U., Daka, B., Leósdóttir, M., Nilsson, P. M., Olsen, M. H., Clark, A. L., Cleland, J. G.F., Delles, C., González, A., Lamiral, Z., Duarte, K., Rossignol, P., Zannad, F., Gudmundsson, P., Jujić, A., Magnusson, M. (2024) Proteomic biomarkers and pathway analysis for progression to heart failure in three epidemiological representative cohorts. European Journal of Heart Failure, (doi: 10.1002/ejhf.3502)
Foley, P.W., Kalra, P.R., Cleland, J.G.F., Petrie, M.C., Kalra, P.A., Squire, I., Campbell, P., Chapman, C., Donnelly, P., Graham, F., Hannah, A., Lang, N.N., Matthews, I., Leslie, S.J., Pellicori, P., Piper, S., Ray, R., Savage, H.O., Spencer, C., Walsh, J., Wong, Y., Ford, I. (2024) Effect of correcting iron deficiency on the risk of serious infection in heart failure insights from the IRONMAN trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3504)
Pontiroli, A. E., Tagliabue, E., Madotto, F., Leoni, O., Antonelli, B., Carluccio, E., Bandera, F., Galati, G., Pellicori, P., Lund, L. H., Ambrosio, G. (2024) Association of non-cardiac comorbidities and sex with long-term re-hospitalization for heart failure. European Journal of Internal Medicine,
Dighriri, A., Timraz, M., Rosaini, N. D., Alkhayl, F., Boyle, J. G., Logan, G., Gray, S. R. (2024) The impact of the time of day on metabolic responses to exercise in adults: a systematic and meta-analysis review. Chronobiology International,
Nadaraia, T., Whittaker, E., Kenyon, I., Boonpor, J., Zhou, Z., Nakada, S., Rochmawati, I. D., Celis-Morales, C., Ward, J., Rod, N. H., Pell, J. P., Minnis, H., Hehlmann, T., Ho, F., Mackay, D. (2024) Childhood maltreatment, adulthood obesity and incident type 2 diabetes: a retrospective cohort study using UK Biobank. International Journal of Obesity, (doi: 10.1038/s41366-024-01652-x)
Alsowail, A. T., Guerrero Wyss, M. T., Ho, F. K., Celis-Morales, C., Gray, S. (2024) The associations of n-3 fatty acid intake with handgrip strength and muscle mass indices in older adults: a cross-sectional study from UK Biobank. Experimental Gerontology,
Riddell, A., Flynn, A., Bergugnat, H., Dowsett, L. B., Miller, A. A. (2024) SDMA as a marker and mediator in cerebrovascular disease. Clinical Science, 138, pp. 1305-1323. (doi: 10.1042/CS20241021)
Parra‐Soto, S., Boonpor, J., Lynskey, N., Araya, C., Ho, F., Pell, J. P., Celis-Morales, C. (2024) Association between visceral adiposity index and cancer risk in the UK Biobank cohort. Cancer, (doi: 10.1002/cncr.35576)
Varga, C. R., Cleland, J. G.F., Abraham, W. T., Lip, G. Y.H., Leyva, F., Hatamizadeh, P. (2024) Implantable cardioverter defibrillator and resynchronization therapy in patients with overt chronic kidney disease. Journal of the American College of Cardiology, 84, pp. 1342-1362. (doi: 10.1016/j.jacc.2024.05.081)
Ho, F., Allan, M., Shao, H., Man, K. K.C., Jani, B. D., Lyall, D., Hastie, C., Fleming, M., Mackay, D., Cleland, J. G.F., Delles, C., Dundas, R., Lewsey, J., Ip, P., Wong, I., Welsh, P., Pearce, A., Wright, C. M., Minnis, H., Katikireddi, V., Pell, J. P. (2024) Maternal and pregnancy factors contributing to the association between area deprivation and infant mortality in England: a retrospective cohort study. Lancet Regional Health - Europe, (doi: 10.1016/j.lanepe.2024.101075)
Lee, M., Petrie, M. C., Cleland, J. G.F., Donnelly, P., Francis, M., Hannah, A., Japp, A. G., Labinjoh, C., Lang, N. N., Mainsty, C., Petrie, C. J., Piper, S. E., Williams, S. G., Ford, I., Kalra, P. R., IRONMAN Trial Investigators, (2024) Administration of ferric derisomaltose for iron deficiency and heart failure during hospital admission or at the clinic – insights from the IRONMAN trial. European Journal of Heart Failure, 26, pp. 2293-2295. (doi: 10.1002/ejhf.3394)
Liu, Q., Celis-Morales, C., Lees, J. S., Sattar, N., Ho, F., Pell, J. P., Mark, P. B., Welsh, P. (2024) Change in physical activity and its association with decline in kidney function: A UK Biobank-based cohort study. Journal of Cachexia, Sarcopenia and Muscle, 15, pp. 2046-2055. (doi: 10.1002/jcsm.13551)
Handelsman, Y. et al. (2024) DCRM 2.0: Multispecialty practice recommendations for the management of diabetes, cardiorenal, and metabolic diseases. Metabolism, 159, (doi: 10.1016/j.metabol.2024.155931)
Cleland, J. G.F. (2024) Home-time is good, but feeling well is better: patient-journey and quality-home-time as endpoints in heart failure trials and registries. Circulation: Heart Failure, 17, (doi: 10.1161/CIRCHEARTFAILURE.124.012263)
Sliwa, K., Rakisheva, A., Viljoen, C., Pfeffer, T., Simpson, M., Jackson, A. M., Petrie, M. C., van der Meer, P., Al Farhan, H., Jovanova, S., Mbakwem, A., Sinagra, G., Van Craenenbroeck, E., Hoevelmann, J., Johnson, M. R., Mindham, R., Chioncel, O., Kahl, K. G., Rosano, G., Tschöpe, C., Mebazaa, A., Seferovic, P., Bauersachs, J. (2024) Living with peripartum cardiomyopathy: A statement from the Heart Failure Association and the Association of Cardiovascular Nursing and Allied Professions of the European Society of Cardiology. European Journal of Heart Failure, 26, pp. 2143-2154. (doi: 10.1002/ejhf.3377)
Pellicori, P., Cuthbert, J. J., Clark, A. L., Cleland, J. G.F. (2024) Managing water and salt balance in heart failure: Is there anything else to consider other than diet and diuretics? European Journal of Heart Failure, 26, pp. 2140-2142. (doi: 10.1002/ejhf.3374)
Keene, D. et al. (2024) Predictors of the efficacy of His bundle pacing in patients with a prolonged PR interval: A stratified analysis of the HOPE‐HF randomized controlled trial. European Journal of Heart Failure, 26, pp. 2261-2268. (doi: 10.1002/ejhf.3367)
Lee, M., Aimo, A., Bayés-Genís, A. (2024) Reverse cardiac remodelling: VICTORIA for inflammation and cardiac metabolism. European Journal of Heart Failure, 26, pp. 2240-2242. (doi: 10.1002/ejhf.3421)
Yu, Y.-L. et al. (2024) Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, 110, pp. 1180-1187. (doi: 10.1136/heartjnl-2023-323796)
Lee, M. M.Y., Codina, P., Tomasoni, D., Aimo, A. (2024) What’s new in heart failure? October 2024. European Journal of Heart Failure, 26, pp. 2049-2054. (doi: 10.1002/ejhf.3492)
Beazer, J. D., Sillars, A., Beck, S., Christoffersen, C., Ferraz, M. J., Mulder, M., Graham, D., Karlsson, H., Ljunggren, S. A., Gill, J. M. R., Freeman, D. J. (2024) Favourable HDL composition in endurance athletes is not associated with changes in HDL in vitro antioxidant and endothelial anti-inflammatory function. Bioscience Reports, (doi: 10.1042/BSR20241165)
Cheng, L., Hammersley, D., Ragavan, A., Javed, S., Mukhopadhyay, S., Gregson, J., Han, J., Khalique, Z., Lota, A., Pantazis, A., Baksi, A. J., Carr‐White, G., de Marvao, A., Ware, J., Tayal, U., Pennell, D. J., Cleland, J. G.F., Prasad, S. K., Halliday, B. P. (2024) Long‐term follow‐up of the TRED ‐ HF trial: Implications for therapy in patients with dilated cardiomyopathy and heart failure remission. European Journal of Heart Failure, (doi: 10.1002/ejhf.3475)
Aman, A., Slob, E. A.W., Ward, J., Sattar, N., Strawbridge, R. (2024) Investigating the association of the effect of genetically proxied PCSK9i with mood disorders using cis-pQTLs: A drug-target Mendelian randomization study. PLoS ONE, 19, (doi: 10.1371/journal.pone.0310396)
Anderson, J. J., Deo, S. V., Welsh, P., Mackay, D. F., Ho, F. K., Ferguson, L. D., Celis-Morales, C., Gill, J.R., Pell, J. P., Sattar, N. (2024) In which common chronic conditions can (or cannot) obesity and lifestyle factors explain higher concentrations of C-reactive protein? Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15949)
Valentova, M., Vatic, M., Garfias-Veitl, T., Sandek, A., Bekfani, T., Jankowska, E. A., Cleland, J. G.F., Clark, A. L., Lainscak, M., Ahmed, A., Jauert, N., Hasenfuss, G., Anker, S. D., Doehner, W., von Haehling, S. (2024) Diabetes mellitus is associated with low exercise capacity and impaired peripheral vasodilation in patients with heart failure – a propensity score-matched stud. Diabetes Research and Clinical Practice,
Greene, S. J. et al. (2024) Cardiovascular and renal treatment in heart failure patients with hyperkalemia or high risk of hyperkalemia: rationale and design of the CARE-HK in HF registry. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2024.08.048)
Zhou, M., Mary, S., Delles, C., Padmanabhan, S., Graham, D., McBride, M. W., Dominiczak, A. (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0)
Cuthbert, J. J., Cleland, J. G. F., Pellicori, P., Clark, A. L. (2024) Natriuresis guided diuresis in patients admitted to hospital with heart failure – barking up the wrong tree? Journal of Cardiac Failure,
Coats, C. J. et al. (2024) Cardiac biomarkers and effects of aficamten in obstructive hypertrophic cardiomyopathy: the SEQUOIA-HCM trial. European Heart Journal, (doi: 10.1093/eurheartj/ehae590)
Morrow, A. et al. (2024) Zibotentan in microvascular angina: a randomized, placebo-controlled, crossover trial. Circulation, (doi: 10.1161/CIRCULATIONAHA.124.069901)
Al-Abdullah, L., Ahern, A., Welsh, P., Logue, J. (2024) A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions. Diabetes, Obesity and Metabolism, 26, pp. 3653-3662. (doi: 10.1111/dom.15706)
van der Meer, P., van Essen, B., Viljoen, C., Böhm, M., Jackson, A., Hilfiker-Kleiner, D., Hoevelmann, J., Mebazaa, A., Farhan, H. A., Goland, S., Ouwerkerk, W., Petrie, M. C., Seferović, P. M., Tromp, J., Sliwa, K., Bauersachs, J. (2024) Bromocriptine treatment and outcomes in peripartum cardiomyopathy: the EORP PPCM registry. European Heart Journal, (doi: 10.1093/eurheartj/ehae559)
Seferović, P. M., Paulus, W. J., Rosano, G., Polovina, M., Petrie, M. C., Jhund, P. S., Tschöpe, C., Sattar, N., Piepoli, M., Papp, Z., Standl, E., Mamas, M. A., Valensi, P., Linhart, A., Lalić, N., Ceriello, A., Döhner, W., Ristić, A., Milinković, I., Seferović, J., Cosentino, F., Metra, M., Coats, A. J.S. (2024) Diabetic myocardial disorder. A clinical consensus statement of the Heart Failure Association of the ESC and the ESC Working Group on Myocardial & Pericardial Diseases. European Journal of Heart Failure, 26, pp. 1893-1903. (doi: 10.1002/ejhf.3347)
Ryan, M., Taylor, D., Dodd, M., Spertus, J. A., Kosiborod, M. N., Shaukat, A., Docherty, K. F., Clayton, T., Perera, D., Petrie, M. C., REVIVED-BCIS2 Investigators, (2024) Effect of PCI on health status in ischemic left ventricular dysfunction: insights from REVIVED-BCIS2. JACC: Heart Failure, 12, pp. 1553-1562. (doi: 10.1016/j.jchf.2024.03.010)
Haney, D., Ma, Y., Dalmacy, D., Pajewski, N. M., Hajjar, I., de Lemos, J. A., Zhang, W., Soliman, E. Z., Ballantyne, C. M., Nambi, V., Sattar, N., Killeen, A. A., Ix, J. H., Shlipak, M. G., Berry, J. D., Ascher, S. B. (2024) High-sensitivity troponin T, NT-proBNP, and cognitive outcomes in SPRINT. Hypertension, 81, pp. 1956-1965. (doi: 10.1161/HYPERTENSIONAHA.124.22876)
Reza, N., Pellicori, P., Starling, R. C. (2024) REVOLUTION in heart failure care and SELECT highlights from the European Society of Cardiology-Heart Failure Association Heart Failure and World Congress on Acute Heart Failure 2024. Journal of Cardiac Failure, 30, pp. 1157-1160. (doi: 10.1016/j.cardfail.2024.05.004)
Krentz, A., Jacob, S., Heiss, C., Sattar, N., Lim, S., Khunti, K., Eckel, R. H. (2024) Rising to the challenge of cardio-renal-metabolic disease in the 21st century: translating evidence into best clinical practice to prevent and manage atherosclerosis. Atherosclerosis, 396, (doi: 10.1016/j.atherosclerosis.2024.118528)
Ponikowski, P. et al. (2024) Hospitalization of symptomatic patients with heart failure and moderate to severe functional mitral regurgitation treated with MitraClip: insights from RESHAPE-HF2. JACC: Heart Failure, (doi: 10.1016/j.jacc.2024.08.027)
Di Fiore, V., Del Punta, L., De Biase, N., Pellicori, P., Gargani, L., Dini, F. L., Armenia, S., Vigni, M. L., Maremmani, D., Masi, S., Taddei, S., Pugliese, N. R. (2024) Integrative assessment of congestion in heart failure using ultrasound imaging. Internal and Emergency Medicine,
Gray, S. R., Montoye, A. H.K., Vondrasek, J. D., Neph, S., Siebert, S., Paul, L., Bachmair, E. M., Basu, N. (2024) Associations of physical activity levels with fatigue in people with inflammatory rheumatic disease in the LIFT trial. Rheumatology Advances in Practice,
Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycaemic control with intraocular pressure in a large general population: Results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)
Liu, Q., Celis-Morales, C., Sattar, N., Welsh, P. (2024) Association of glycemic control with intraocular pressure in a large general population: results from the UK Biobank. Diabetes, Obesity and Metabolism, (doi: 10.1111/dom.15865)
Graham, F. J., Guha, K., Cleland, J. G., Kalra, P. R. (2024) Treating iron deficiency in patients with heart failure: what, why, when, how, where and who. Heart, (doi: 10.1136/heartjnl-2022-322030)
McLaren, J., Gao, X., Ghouri, N., Freeman, D. J., Richardson, J., Sattar, N., Gill, J. M.R. (2024) Weight gain leads to greater adverse metabolic responses in South Asian compared with white European men: the GlasVEGAS study. Nature Metabolism, 6, pp. 1632-1645. (doi: 10.1038/s42255-024-01101-z)
Cleland, J., Pellicori, P., Graham, F. J., Lane, R., Petrie, M. C., Ahmed, F., Squire, I. B., Ludman, A., Japp, A., Al-Mohammad, A., Clark, A. L., Szwejkowski, B., Critoph, C., Chong, V., Schiff, R., Nageh, T., Glover, J., McMurray, J. J.V., Thomson, E. A., Robertson, M., Ford, I., Kalra, P. A., Kalra, P. R. (2024) The IRONMAN trial of intravenous iron for heart failure. Adjudication of hospitalizations and deaths. Journal of the American College of Cardiology,
Petermann-Rocha, F., Zhou, Z., Mathers, J. C., Celis-Morales, C., Raubenheimer, D., Sattar, N., Pell, J. P., Forrest, E., Ho, F. K. (2024) Diet modifies the association between alcohol consumption and severe alcohol-related liver disease incidence. Nature Communications, 15, (doi: 10.1038/s41467-024-51314-9)
Cao, T. H., Tay, W. T., Jones, D. J.L., Cleland, J. G.F., Tromp, J., Emmens, J. E., Teng, T.‐H. K., Chandramouli, C., Slingsby, O. C., Anker, S. D., Dickstein, K., Filippatos, G., Lang, C. C., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Anand, I. S., Lam, C. S.P., Voors, A. A., Ng, L. L. (2024) Heart failure with improved versus persistently reduced left ventricular ejection fraction: A comparison of the BIOSTAT‐CHF (European) study with the ASIAN‐HF registry. European Journal of Heart Failure, (doi: 10.1002/ejhf.3378)
AlOzairi, E., AlSaraf, H., AlOzairi, A., Hamdan, Y., Alesmaeel, B., AlSaeed, D., Abdalla, M., Gray, S. R. (2024) Validity of the Arabic International Physical Activity Questionnaire to measure moderate to vigorous physical activity in people with diabetes. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy,
Kazmi, S., Kambhampati, C., Rigby, A. S., Cleland, J. G.F., Kazmi, K. S., Cuthbert, J., Pellicori, P., Clark, A. L. (2024) Disease progression in chronic heart failure is linear: insights from multistate modelling. European Journal of Heart Failure, (doi: 10.1002/ejhf.3400)
Coats, C. J. et al. (2024) Dosing and safety profile of aficamten in symptomatic obstructive hypertrophic cardiomyopathy: results from from SEQUOIA‐HCM. Journal of the American Heart Association, 13, (doi: 10.1161/JAHA.124.035993)
Hayman, O., Combet, E., Witard, O. C., Gray, S. R. (2024) Long-chain n-3 polyunsaturated fatty acid supplementation and neuromuscular function in older adults. Current Opinion in Clinical Nutrition and Metabolic Care, 27, pp. 486-491. (doi: 10.1097/MCO.0000000000001065)
Gustafsson, F., Petrie, M. C., Komtebedde, J., Swarup, V., Winkler, S., Hasenfuß, G., Borlaug, B. A., Mohan, R. C., Flaherty, J. D., Sverdlov, A. L., Fail, P. S., Chung, E. S., Lurz, P., Lilly, S., Kaye, D. M., Cleland, J. G.F., Cikes, M., Leon, M. B., Cutlip, D. E., van Veldhuisen, D. J., Solomon, S. D., Shah, S. J. (2024) 2-year outcomes of an atrial shunt device in HFpEF/HFmrEF: results from REDUCE LAP-HF II. JACC: Heart Failure, 12, pp. 1425-1438. (doi: 10.1016/j.jchf.2024.04.011)
Sudesh, S., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Friedman, D. J., Gold, M. R., Kutyifa, V., Linde, C., Tang, A. S., Olivas-Martinez, A., Inoue, L. Y.T., Sanders, G. D., Al-Khatib, S. M. (2024) Cardiac resynchronization therapy in ischemic versus non-ischemic cardiomyopathy: patient-level meta-analysis of seven randomized clinical trials. JACC: Heart Failure,
Rosano, G. M.C. et al. (2024) Differences in presentation, diagnosis and management of heart failure in women. A scientific statement of the Heart Failure Association of the ESC. European Journal of Heart Failure, 26, pp. 1669-1686. (doi: 10.1002/ejhf.3284)
Carberry, J., Petrie, M. C., Lee, M. M.Y., Brooksbank, K., Campbell, R. T., Good, R., Jhund, P. S., Kellman, P., Lang, N. N., Mangion, K., Mark, P. B., McConnachie, A., McMurray, J. J.V., Meyer, B., Orchard, V., Shaukat, A., Watkins, S., Welsh, P., Sattar, N., Berry, C., Docherty, K. F. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure, 11, pp. 2001-2012. (doi: 10.1002/ehf2.14830)
Grobbee, D. E., Filippatos, G., Desai, N. R., Coats, A. J.S., Pinto, F., Rosano, G. M.C., Cleland, J., Kammerer, J., Ramirez de Arellano, A. (2024) Epidemiology and risk factors for hyperkalaemia in heart failure. ESC Heart Failure, 11, pp. 1821-1840. (doi: 10.1002/ehf2.14661)
Docherty, K. F., McMurray, J. J.V., Kalra, P., Cleland, J. G.F., Lang, N. N., Petrie, M. C., Robertson, M., Ford, I. (2024) Intravenous iron and SGLT2 inhibitors in iron-deficient patients with heart failure and reduced ejection fraction. ESC Heart Failure, 11, pp. 1875-1879. (doi: 10.1002/ehf2.14742)
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2021
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Halliday, B. P., Owen, R., Gregson, J., Vassiliou, V., Chen, X., Wage, R., Lota, A. S., Khalique, Z., Tayal, U., Hammersley, D. J., Jones, R. E., Baksi, A. J., Cowie, M. R., Cleland, J. G.F., Pennell, D. J., Prasad, S. K. (2021) Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy – insights from TRED‐HF. European Journal of Heart Failure, 23, pp. 293-301. (doi: 10.1002/ejhf.2063)
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2020
Brown, R., Welsh, P., Logue, J. (2020) Systematic review of clinical guidelines for lipid-lowering in the secondary prevention of cardiovascular disease events. Open Heart, 7, (doi: 10.1136/openhrt-2020-001396)
Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)
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Goncalves Soares, A., Kilpi, F., Fraser, A., Nelson, S. M., Sattar, N., Welsh, P. I., Tilling, K., Lawlor, D. A. (2020) Longitudinal changes in reproductive hormones through the menopause transition in the Avon Longitudinal Study of Parents and Children (ALSPAC) Scientific Reports, 10, (doi: 10.1038/s41598-020-77871-9)
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Kelly, P., Williamson, C., Baker, G., Davis, A., Broadfield, S., Coles, A., Logan, G., Connell, H., Pell, J. P., Gray, C., Gill, J. M.R. (2020) Beyond cycle lanes and large-scale infrastructure: a scoping review of initiatives that groups and organisations can implement to promote cycling for the Cycle Nation Project. British Journal of Sports Medicine, 54, pp. 1405-1415. (doi: 10.1136/bjsports-2019-101447)
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Felker, G. M., Solomon, S. D., McMurray, J. J.V., Cleland, J. G.F., Abbasi, S. A., Malik, F. I., Zhang, H., Globe, G., Teerlink, J. R. (2020) Effects of omecamtiv mecarbil on symptoms and health-related quality of life in patients with chronic heart failure: results from the COSMIC-HF study. Circulation: Heart Failure, 13, (doi: 10.1161/CIRCHEARTFAILURE.120.007814)
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2019
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2017
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Stam-Slob, M. C., Visseren, F. L.J., Wouter Jukema, J., van der Graaf, Y., Poulter, N. R., Gupta, A., Sattar, N., Macfarlane, P. W., Kearney, P. M., de Craen, A. J.M., Trompet, S. (2017) Personalized absolute benefit of statin treatment for primary or secondary prevention of vascular disease in individual elderly patients. Clinical Research in Cardiology, 106, pp. 58-68. (doi: 10.1007/s00392-016-1023-8)
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Petermann, F., Leiva, A. M., Martínez, M. A., Salas, C., Garrido-Méndez, A., Celis-Morales, C. (2017) Consumo de bebidas azúcaradas ayer y hoy: ¿cuál es el escenario para la población chilena? = Sugar-sweetened beverage consumption, what is the scenario for Chile? Revista Chilena de Nutrición, 44, pp. 400-401. (doi: 10.4067/s0717-75182017000400400)
Celis-Morales, C., Lyall, D. M., Gray, S., Steell, L., Anderson, J., Iliodromiti, S., Welsh, P., Guo, Y., Petermann, F., Mackay, D. F., Bailey, M. E.S., Pell, J., Gill, J. M.R., Sattar, N. (2017) Dietary fat and total energy intake modifies the association of genetic profile risk score on obesity: evidence from 48 170 UK Biobank participants. International Journal of Obesity, 41, pp. 1761-1768. (doi: 10.1038/ijo.2017.169)
Agca, R. et al. (2017) EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update. Annals of the Rheumatic Diseases, 76, pp. 17-28. (doi: 10.1136/annrheumdis-2016-209775)
Petermann Rocha, F., Durán Fernández, E., Labraña Torres, A. M., Celis-Morales, C. (2017) Efecto de una consulta nutricional protocolizada sobre el estado nutricional y hábitos alimentarios de adultos con sobrepeso y obesidad = Effect of a structured nutritional consultation on weight loss and eating habits in overweight and obese adults. Revista Chilena de Nutrición, 44, pp. 341-349. (doi: 10.4067/s0717-75182017000400341)
Liu, D. J. et al. (2017) Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics, 49, pp. 1758-1766. (doi: 10.1038/ng.3977)
Petermann, F., Durán, E., Labraña, A. M., Martínez, M. A., Garrido-Méndez, A., Poblete-Valderrama, F., Díaz, X., Salas, C., Celis-Morales, C. (2017) Factores asociados al desarrollo de obesidad en Chile: resultados de la Encuesta Nacional de Salud 2009-2010 = Risk factors for obesity: analysis of the 2009-2010 Chilean Health Survey. Revista Medica de Chile, 145, pp. 716-722. (doi: 10.4067/s0034-98872017000600716)
Cuthbert, J. J., Pellicori, P., Clark, A. L. (2017) Interatrial shunt devices for heart failure with normal ejection fraction: a technology update. Medical Devices: Evidence and Research, 10, pp. 123-132. (doi: 10.2147/mder.s113105)
Skaaby, T. et al. (2017) Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium. Scientific Reports, 7, (doi: 10.1038/s41598-017-01977-w)
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2016
Torabi, A., Cleland, J. G.F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., Thackray, S., Hoye, A., Alamgir, F., Goode, K., Rigby, A., Clark, A. L. (2016) Influence of case definition on incidence and outcome of acute coronary syndromes. Open Heart, 3, (doi: 10.1136/openhrt-2016-000487)
Ramirez-Campillo, R., Diaz, D., Martinez-Salazar, C., Valdés-Badilla, P., Delgado-Floody, P., Méndez-Rebolledo, G., Cañas-Jamet, R., Cristi-Montero, C., García-Hermoso, A., Celis-Morales, C., Moran, J., Buford, T. W., Rodriguez-Mañas, L., Alonso-Martinez, A. M., Izquierdo, M. (2016) Effects of different doses of high-speed resistance training on physical performance and quality of life in older women: a randomized controlled trial. Clinical Interventions in Aging, 2016, pp. 1797-1804. (doi: 10.2147/CIA.S121313)
Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Solomon, S. D., Adams, Jr., K. F., Cleland, J. G.F., Ezekowitz, J. A., Goudev, A., Macdonald, P., Metra, M., Mitrovic, V., Ponikowski, P., Serpytis, P., Spinar, J., Tomcsányi, J., Vandekerckhove, H. J., Voors, A. A., Monsalvo, M. L., Johnston, J., Malik, F. I., Honarpour, N. (2016) Chronic oral study of myosin activation to increase contractility in heart failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. Lancet, 388, pp. 2895-2903. (doi: 10.1016/S0140-6736(16)32049-9)
White, S. L., Lawlor, D. A., Briley, A. L., Godfrey, K. M., Nelson, S. M., Oteng-Ntim, E., Robson, S. C., Sattar, N., Seed, P. T., Vieira, M. C., Welsh, P., Whitworth, M., Poston, L., Pasupathy, D. (2016) Early antenatal prediction of gestational diabetes in obese women: development of prediction tools for targeted intervention. PLoS ONE, 11, (doi: 10.1371/journal.pone.0167846)
Carrick, D., Haig, C., Ahmed, N., Carberry, J., Teng Yue May, V., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davies, A., Abouzaid, A. M., Mordi, I., Ford, I., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment elevation myocardial infarction. Circulation, 134, pp. 1833-1847. (doi: 10.1161/CIRCULATIONAHA.116.022603)
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Pellicori, P., Cleland, J. G.F., Zhang, J., Kallvikbacka-Bennett, A., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L. (2016) Cardiac dysfunction, congestion and loop diuretics: their relationship to prognosis in heart failure. Cardiovascular Drugs and Therapy, 30, pp. 599-609. (doi: 10.1007/s10557-016-6697-7)
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McCallum, J. E., Mackenzie, A. E., Divorty, N., Clarke, C., Delles, C., Milligan, G., Nicklin, S. A. (2016) G protein-coupled receptor 35 mediates human saphenous vein vascular smooth muscle cell migration and endothelial cell proliferation. Journal of Vascular Research, 52, pp. 383-395. (doi: 10.1159/000444754)
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2015
Cleland, J. G.F., Mareev, Y. (2015) CRT for heart failure and ESRD: more trials or more thought needed? Journal of the American College of Cardiology, 66, pp. 2630-2632. (doi: 10.1016/j.jacc.2015.10.022)
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Da Boit, M., Gabriel, B.M., Gray, P., Gray, S.R. (2015) The effect of fish oil, vitamin D and protein on URTI incidence in young active people. International Journal of Sports Medicine, 36, pp. 426-430. (doi: 10.1055/s-0034-1394464)
Davison, B. A., Metra, M., Cotter, G., Massie, B. M., Cleland, J. G.F., Dittrich, H. C., Edwards, C., Filippatos, G., Givertz, M. M., Greenberg, B., Ponikowski, P., Voors, A. A., O’Connor, C. M., Teerlink, J. R. (2015) Worsening heart failure following admission for acute heart failure: a pooled analysis of the PROTECT and RELAX-AHF studies. JACC: Heart Failure, 3, pp. 395-403. (doi: 10.1016/j.jchf.2015.01.007)
Ravassa, S., Kuznetsova, T., Varo, N., Thijs, L., Delles, C., Dominiczak, A., Díez, J., Staessen, J. A. (2015) Biomarkers of cardiomyocyte injury and stress identify left atrial and left ventricular remodelling and dysfunction: a population-based study. International Journal of Cardiology, 185, pp. 177-185. (doi: 10.1016/j.ijcard.2015.03.046)
Malik, M. O., Govan, L., Petrie, J. R., Ghouri, N., Leese, G., Fischbacher, C., Colhoun, H., Philip, S., Wild, S., McCrimmon, R., Sattar, N., Lindsay, R. S. (2015) Ethnicity and risk of cardiovascular disease (CVD): 4.8 year follow-up of patients with type 2 diabetes living in Scotland. Diabetologia, 58, pp. 716-725. (doi: 10.1007/s00125-015-3492-0)
Siervo, M., Oggioni, C., Lara, J., Celis-Morales, C., Mathers, J. C., Battezzati, A., Leone, A., Tagliabue, A., Spadafranca, A., Bertoli, S. (2015) Age-related changes in resting energy expenditure in normal weight, overweight and obese men and women. Maturitas, 80, pp. 406-413. (doi: 10.1016/j.maturitas.2014.12.023)
Ghouri, N., Purves, D., Deans, K. A., Logan, G., McConnachie, A., Wilson, J., Gill, J. M. R., Sattar, N. (2015) An investigation of two-dimensional ultrasound carotid plaque presence and intima media thickness in middle-aged South Asian and European men living in the United Kingdom. PLoS ONE, 10, (doi: 10.1371/journal.pone.0123317)
McInnes, I. B., Thompson, L., Giles, J. T., Bathon, J. M., Salmon, J. E., Beaulieu, A. D., Codding, C. E., Carlson, T. H., Delles, C., Lee, J. S., Sattar, N. (2015) Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study. Annals of the Rheumatic Diseases, 74, pp. 694-702. (doi: 10.1136/annrheumdis-2013-204345)
Santangeli, L., Sattar, N., Huda, S. H. (2015) Impact of maternal obesity on perinatal and childhood outcomes. Best Practice and Research: Clinical Obstetrics and Gynaecology, 29, pp. 438-448. (doi: 10.1016/j.bpobgyn.2014.10.009)
Mischak, H., Delles, C., Vlahou, A., Vanholder, R. (2015) Proteomic biomarkers in kidney disease: issues in development and implementation. Nature Reviews Nephrology, 11, pp. 221-232. (doi: 10.1038/nrneph.2014.247)
Cleland, J. G.F., Butcher, C. (2015) When is it appropriate to withdraw cardiac resynchronization therapy? Guesses and evidence. JACC: Heart Failure, 3, pp. 337-339. (doi: 10.1016/j.jchf.2015.01.003)
Pellicori, P., Zhang, J., Lukaschuk, E., Joseph, A. C., Bourantas, C. V., Loh, H., Bragadeesh, T., Clark, A. L., Cleland, J. G.F. (2015) Left atrial function measured by cardiac magnetic resonance imaging in patients with heart failure: clinical associations and prognostic value. European Heart Journal, 36, pp. 733-742. (doi: 10.1093/eurheartj/ehu405)
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Metra, M., Cotter, G., El-Khorazaty, J., Davison, B. A., Milo, O., Carubelli, V., Bourge, R. C., Cleland, J. G., Jondeau, G., Krum, H., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Rainisio, M., Kobrin, I., McMurray, J. J., Teerlink, J. R. (2015) Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study. Journal of Cardiac Failure, 21, pp. 179-88. (doi: 10.1016/j.cardfail.2014.12.012)
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Eastwood, S. V., Tillin, T., Dehbi, H.-M., Wright, A., Forouhi, N. G., Godsland, I., Whincup, P., Sattar, N., Hughes, A. D., Chaturvedi, N. (2015) Ethnic differences in associations between fat deposition and incident diabetes and underlying mechanisms: The SABRE study. Obesity, 23, pp. 699-706. (doi: 10.1002/oby.20997)
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Musunuru, K., Hickey, K. T., Al-Khatib, S. M., Delles, C., Fornage, M., Fox, C. S., Frazier, L., Gelb, B. D., Herrington, D. M., Lanfear, D. E., Rosand, J. (2015) Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association. Circulation: Cardiovascular Genetics, 8, pp. 216-242. (doi: 10.1161/HCG.0000000000000020)
Pellicori, P., Costanzo, P. (2015) Betabloccanti in pazienti con scompenso cardiaco e fibrillazione atriale = [Betablockers in patients with heart failure and atrial fibrillation] Giornale italiano di cardiologia, 16, pp. 613-616. (doi: 10.1714/2066.22428)
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Welsh, P., Preiss, D., Touyz, R. M. (2015) Biomarkers of hypertension and cardiovascular disease. Royal Society of Chemistry
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Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Jhund, P. S., Brunton, A. P.T., Anand, I. S., McKelvie, R. S., Komajda, M., Zile, M. R., Carson, P. E., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with coronary artery disease and angina. Circulation: Heart Failure, 8, pp. 717-724. (doi: 10.1161/CIRCHEARTFAILURE.114.002024)
Preiss, D., Sattar, N. (2015) Does the LDL receptor play a role in the risk of developing type 2 diabetes? JAMA: Journal of the American Medical Association, 313, pp. 1016-1017. (doi: 10.1001/jama.2015.1275)
Bis, J. C. et al. (2015) Drug-gene interactions of antihypertensive medications and risk of incident cardiovascular disease: a pharmacogenomics study from the CHARGE consortium. PLoS ONE, 10, (doi: 10.1371/journal.pone.0140496)
Díaz Martínez, X., Bastías, C. M., Celis-Moralesl, C., Salas, C., Moral, P. V. (2015) Efecto de un programa de actividad física y alimentación saludable aplicado a hijos y padres para la prevención de la obesidad infantil = [Effect of a healthy eating and physical activity intervention program on chilhood obesity] Nutricion Hospitalaria, 32, pp. 110-117. (doi: 10.3305/nh.2015.32.1.9122)
Burska, A.N., Sakthiswary, R., Sattar, N. (2015) Effects of tumour necrosis factor antagonists on insulin sensitivity/resistance in rheumatoid arthritis: a systematic review and meta-analysis. PLoS ONE, 10, (doi: 10.1371/journal.pone.0128889)
Pellicori, P., Kaur, K., Clark, A. L. (2015) Fluid management in patients with chronic heart failure. Cardiac Failure Review, 1, pp. 90-95. (doi: 10.15420/cfr.2015.1.2.90)
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van Leeuwen, E. M. et al. (2015) Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications, 6, (doi: 10.1038/ncomms7065)
Mistry, H.D., Eisele, N., Escher, G., Dick, B., Surbek, D., Delles, C., Currie, G., Schlembach, D., Mohaupt, M.G., Gennari-Moser, C. (2015) Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum. Reproductive Biology and Endocrinology, 13, (doi: 10.1186/s12958-015-0100-6)
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Celis-Morales, C. et al. (2015) How reliable is internet-based self-reported identity, socio-demographic and obesity measures in European adults? Genes and Nutrition, 10, (doi: 10.1007/s12263-015-0476-0)
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Dalzell, J. R., Cannon, J. A., Simpson, J., Gardner, R. S., Petrie, M. C. (2015) Improving outcomes in peripartum cardiomyopathy. Expert Review of Cardiovascular Therapy, 13, pp. 665-671. (doi: 10.1586/14779072.2015.1040767)
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Badar, A. A., Brunton, A. P.T., Mahmood, A. H., Dobbin, S., Pozzi, A., McMinn, J. F., Sinclair, A. J.E., Gardner, R. S., Petrie, M. C., Curry, P. A., Al-Attar, N. H.K., Pettit, S. J. (2015) The management of patients with aortic regurgitation and severe left ventricular dysfunction: a systematic review. Expert Review of Cardiovascular Therapy, 13, pp. 915-922. (doi: 10.1586/14779072.2015.1067139)
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PGR Students
- Postgraduate Research Student
- Research title: n/a
- Postgraduate Research Student
- Research title: Resistance training effects on young adults with diabetes
Our unit strives to better understand the links between metabolic and endocrine diseases including diabetes and cardiovascular diseases including atherosclerotic vascular disease and heart failure. We study general populations of interest and specific subgroups of interest to investigate the way that risk factors and mechanisms change in different people, including by ethnicity, gender, and socioeconomic deprivation.
Ongoing research topics include:
- Epidemiology of diabetes and other metabolic conditions.
- Biomarkers of cardiometabolic disease.
- Imaging studies of cardiometabolic diseases.
- Intervention studies including mechanistic randomized controlled clinical trials.
We use this knowledge both to develop and understand new cardiovascular therapies and target existing therapies to at risk groups more effectively.