Dr Alexandra Riddell
- Research Associate (School of Cardiovascular & Metabolic Health)
telephone:
0141 330 3301
email:
Alexandra.Riddell@glasgow.ac.uk
pronouns:
She/her/hers
Research interests
Research Theme: Vascular Diseases and Comorbidities
Research groups
Publications
2026
Flynn, A. et al. (2026) Direct evidence implicating the ADMA-DDAH1 pathway in cerebrovascular dysfunction and stroke pathogenesis in mice. British Journal of Pharmacology, (Accepted for Publication)
2025
Kaneko, N. et al. (2025) Pharmacological study of the safety, efficacy and potential of M201-A on paroxysmal and persistent atrial fibrillation. Journal of Pharmacology and Experimental Therapeutics, 392(8), 103652. (doi: 10.1016/j.jpet.2025.103652)
Reel, S. et al. (2025) Identification of hypertension subtypes using microRNA profiles and machine learning. European Journal of Endocrinology, 192(4), pp. 418-428. (doi: 10.1093/ejendo/lvaf052) (PMID:40105001)
2024
Riddell, Alexandra ORCID: https://orcid.org/0000-0003-4566-8680, Flynn, Arun, Bergugnat, Hugo, Dowsett, Laura B.
ORCID: https://orcid.org/0000-0002-3356-8183 and Miller, Alyson A.
ORCID: https://orcid.org/0000-0001-7755-9046
(2024)
SDMA as a marker and mediator in cerebrovascular disease.
Clinical Science, 138(20),
pp. 1305-1323.
(doi: 10.1042/CS20241021)
Loughrey, C. et al. (2024) A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic action: Pre-clinical and phase I study. British Journal of Pharmacology, 181(18), pp. 3401-3419. (doi: 10.1111/bph.16379) (PMID:38773354)
2023
Martin, T. P. et al. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119(16), 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107) (PMID:37433039) (PMCID:PMC10730241)
2022
Gerganova, Gabriela ORCID: https://orcid.org/0000-0002-3273-4100, Riddell, Alexandra
ORCID: https://orcid.org/0000-0003-4566-8680 and Miller, Alyson A.
ORCID: https://orcid.org/0000-0001-7755-9046
(2022)
CNS border-associated macrophages in the homeostatic and ischaemic brain.
Pharmacology and Therapeutics, 240,
108220.
(doi: 10.1016/j.pharmthera.2022.108220)
(PMID:35667516)
Reel, P. S. et al. (2022) Machine learning for classification of hypertension subtypes using multi-omics: a multi-centre, retrospective, data-driven study. EBioMedicine, 84, 104276. (doi: 10.1016/j.ebiom.2022.104276) (PMID:36179553) (PMCID:PMC9520210)
He, W. et al. (2022) Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size. Cardiovascular Research, 118(6), pp. 1535-1547. (doi: 10.1093/cvr/cvab204) (PMID:34132807)
2021
MacKenzie, Scott M. ORCID: https://orcid.org/0000-0002-4593-4101, Saunders, Hannah, van Kralingen, Josie C., Robertson, Stacy
ORCID: https://orcid.org/0000-0002-0747-5493, Riddell, Alexandra
ORCID: https://orcid.org/0000-0003-4566-8680, Zennaro, Maria-Christina and Davies, Eleanor
ORCID: https://orcid.org/0000-0001-8128-5404
(2021)
Circulating microRNAs as diagnostic markers in primary aldosteronism.
Cancers, 13(21),
5312.
(doi: 10.3390/cancers13215312)
(PMCID:PMC8582381)
2020
Riddell, Alexandra ORCID: https://orcid.org/0000-0003-4566-8680, McBride, Martin
ORCID: https://orcid.org/0000-0002-6323-124X, Braun, Thomas, Nicklin, Stuart A.
ORCID: https://orcid.org/0000-0002-9691-6210, Cameron, Ewan
ORCID: https://orcid.org/0000-0001-8311-1491, Loughrey, Christopher Michael
ORCID: https://orcid.org/0000-0003-1297-9159 and Martin, Tamara P.
ORCID: https://orcid.org/0000-0002-2509-2613
(2020)
RUNX1: an emerging therapeutic target for cardiovascular disease.
Cardiovascular Research, 116(8),
pp. 1410-1423.
(doi: 10.1093/cvr/cvaa034)
(PMID:32154891)
(PMCID:PMC7314639)
McArthur, Lisa ORCID: https://orcid.org/0000-0002-8014-640X, Riddell, Alexandra
ORCID: https://orcid.org/0000-0003-4566-8680, Chilton, Lisa, Smith, Godfrey L.
ORCID: https://orcid.org/0000-0003-4821-9741 and Nicklin, Stuart A.
ORCID: https://orcid.org/0000-0002-9691-6210
(2020)
Regulation of connexin 43 by interleukin 1β in adult rat cardiac fibroblasts and effects in an adult rat cardiac myocyte: fibroblast co-culture model.
Heliyon, 6(1),
e03031.
(doi: 10.1016/j.heliyon.2019.e03031)
(PMID:31909243)
(PMCID:PMC6940628)
2019
Ugusman, Azizah Binti, Riddell, Alex ORCID: https://orcid.org/0000-0003-4566-8680 and Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840
(2019)
Effect of peroxynitrite (ONOO−) on the function of murine perivascular adipose tissue.
Pharmacology and Pharmacy, 10(4),
pp. 194-204.
(doi: 10.4236/pp.2019.104017)
Hall, J.L., Owen, L., Riddell, A. ORCID: https://orcid.org/0000-0003-4566-8680, Church, D.B., Brodbelt, D.C. and O'Neill, D.G.
(2019)
Urinary incontinence in male dogs under primary veterinary care in England: prevalence and risk factors.
Journal of Small Animal Practice, 60(2),
pp. 86-95.
(doi: 10.1111/jsap.12951)
(PMID:30387152)
2018
McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137(1), pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911) (PMID:29030345) (PMCID:PMC5757664)
2017
O'Neill, D.G., Riddell, A. ORCID: https://orcid.org/0000-0003-4566-8680, Church, D.B., Owen, L., Brodbelt, D.C. and Hall, J.L.
(2017)
Urinary incontinence in bitches under primary veterinary care in England: prevalence and risk factors.
Journal of Small Animal Practice, 58(12),
pp. 685-693.
(doi: 10.1111/jsap.12731)
(PMID:28881018)
Articles
Flynn, A. et al. (2026) Direct evidence implicating the ADMA-DDAH1 pathway in cerebrovascular dysfunction and stroke pathogenesis in mice. British Journal of Pharmacology, (Accepted for Publication)
Kaneko, N. et al. (2025) Pharmacological study of the safety, efficacy and potential of M201-A on paroxysmal and persistent atrial fibrillation. Journal of Pharmacology and Experimental Therapeutics, 392(8), 103652. (doi: 10.1016/j.jpet.2025.103652)
Reel, S. et al. (2025) Identification of hypertension subtypes using microRNA profiles and machine learning. European Journal of Endocrinology, 192(4), pp. 418-428. (doi: 10.1093/ejendo/lvaf052) (PMID:40105001)
Riddell, Alexandra ORCID: https://orcid.org/0000-0003-4566-8680, Flynn, Arun, Bergugnat, Hugo, Dowsett, Laura B.
ORCID: https://orcid.org/0000-0002-3356-8183 and Miller, Alyson A.
ORCID: https://orcid.org/0000-0001-7755-9046
(2024)
SDMA as a marker and mediator in cerebrovascular disease.
Clinical Science, 138(20),
pp. 1305-1323.
(doi: 10.1042/CS20241021)
Loughrey, C. et al. (2024) A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic action: Pre-clinical and phase I study. British Journal of Pharmacology, 181(18), pp. 3401-3419. (doi: 10.1111/bph.16379) (PMID:38773354)
Martin, T. P. et al. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119(16), 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107) (PMID:37433039) (PMCID:PMC10730241)
Gerganova, Gabriela ORCID: https://orcid.org/0000-0002-3273-4100, Riddell, Alexandra
ORCID: https://orcid.org/0000-0003-4566-8680 and Miller, Alyson A.
ORCID: https://orcid.org/0000-0001-7755-9046
(2022)
CNS border-associated macrophages in the homeostatic and ischaemic brain.
Pharmacology and Therapeutics, 240,
108220.
(doi: 10.1016/j.pharmthera.2022.108220)
(PMID:35667516)
Reel, P. S. et al. (2022) Machine learning for classification of hypertension subtypes using multi-omics: a multi-centre, retrospective, data-driven study. EBioMedicine, 84, 104276. (doi: 10.1016/j.ebiom.2022.104276) (PMID:36179553) (PMCID:PMC9520210)
He, W. et al. (2022) Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size. Cardiovascular Research, 118(6), pp. 1535-1547. (doi: 10.1093/cvr/cvab204) (PMID:34132807)
MacKenzie, Scott M. ORCID: https://orcid.org/0000-0002-4593-4101, Saunders, Hannah, van Kralingen, Josie C., Robertson, Stacy
ORCID: https://orcid.org/0000-0002-0747-5493, Riddell, Alexandra
ORCID: https://orcid.org/0000-0003-4566-8680, Zennaro, Maria-Christina and Davies, Eleanor
ORCID: https://orcid.org/0000-0001-8128-5404
(2021)
Circulating microRNAs as diagnostic markers in primary aldosteronism.
Cancers, 13(21),
5312.
(doi: 10.3390/cancers13215312)
(PMCID:PMC8582381)
Riddell, Alexandra ORCID: https://orcid.org/0000-0003-4566-8680, McBride, Martin
ORCID: https://orcid.org/0000-0002-6323-124X, Braun, Thomas, Nicklin, Stuart A.
ORCID: https://orcid.org/0000-0002-9691-6210, Cameron, Ewan
ORCID: https://orcid.org/0000-0001-8311-1491, Loughrey, Christopher Michael
ORCID: https://orcid.org/0000-0003-1297-9159 and Martin, Tamara P.
ORCID: https://orcid.org/0000-0002-2509-2613
(2020)
RUNX1: an emerging therapeutic target for cardiovascular disease.
Cardiovascular Research, 116(8),
pp. 1410-1423.
(doi: 10.1093/cvr/cvaa034)
(PMID:32154891)
(PMCID:PMC7314639)
McArthur, Lisa ORCID: https://orcid.org/0000-0002-8014-640X, Riddell, Alexandra
ORCID: https://orcid.org/0000-0003-4566-8680, Chilton, Lisa, Smith, Godfrey L.
ORCID: https://orcid.org/0000-0003-4821-9741 and Nicklin, Stuart A.
ORCID: https://orcid.org/0000-0002-9691-6210
(2020)
Regulation of connexin 43 by interleukin 1β in adult rat cardiac fibroblasts and effects in an adult rat cardiac myocyte: fibroblast co-culture model.
Heliyon, 6(1),
e03031.
(doi: 10.1016/j.heliyon.2019.e03031)
(PMID:31909243)
(PMCID:PMC6940628)
Ugusman, Azizah Binti, Riddell, Alex ORCID: https://orcid.org/0000-0003-4566-8680 and Kennedy, Simon
ORCID: https://orcid.org/0000-0003-0887-5840
(2019)
Effect of peroxynitrite (ONOO−) on the function of murine perivascular adipose tissue.
Pharmacology and Pharmacy, 10(4),
pp. 194-204.
(doi: 10.4236/pp.2019.104017)
Hall, J.L., Owen, L., Riddell, A. ORCID: https://orcid.org/0000-0003-4566-8680, Church, D.B., Brodbelt, D.C. and O'Neill, D.G.
(2019)
Urinary incontinence in male dogs under primary veterinary care in England: prevalence and risk factors.
Journal of Small Animal Practice, 60(2),
pp. 86-95.
(doi: 10.1111/jsap.12951)
(PMID:30387152)
McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137(1), pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911) (PMID:29030345) (PMCID:PMC5757664)
O'Neill, D.G., Riddell, A. ORCID: https://orcid.org/0000-0003-4566-8680, Church, D.B., Owen, L., Brodbelt, D.C. and Hall, J.L.
(2017)
Urinary incontinence in bitches under primary veterinary care in England: prevalence and risk factors.
Journal of Small Animal Practice, 58(12),
pp. 685-693.
(doi: 10.1111/jsap.12731)
(PMID:28881018)