Cardio-oncology

Led by Professor Ninian Lang, the Cardio-Oncology Unit in SCMH focuses on the potential adverse cardiovascular effects of cancer and its treatment.

Staff

Publications

2024

Ramses, R., Kennedy, S., Good, R., Oldroyd, K. G., Mcginty, S. (2024) Performance of drug-coated balloons in coronary and below-the-knee arteries: anatomical, physiological and pathological considerations. Vascular Pharmacology, 155, (doi: 10.1016/j.vph.2024.107366)

Sullivan, M. K., Lees, J. S., Rosales, B. M., Cutting, R., Wyld, M. L., Woodward, M., Webster, A. C., Mark, P. B., De La Mata, N. (2024) Sex and the relationship between cardiometabolic risk factors and estimated GFR Decline: a population-based cohort study. American Journal of Kidney Diseases,

Yu, Y.-L. et al. (2024) Urinary proteomic signature of mineralocorticoid receptor antagonism by spironolactone: evidence from the HOMAGE trial. Heart, (doi: 10.1136/heartjnl-2023-323796)

Lees, J. S., Crowther, J., Hanlon, P., Butterly, E., Wild, S. H., Mair, F. S., Guthrie, B., Gillies, K., Dias, S., Welton, N. J., Katikireddi, S. V., McAllister, D. A. (2024) Participant characteristics and exclusion from trials: a meta-analysis of individual participant-level data from phase 3/4 industry-funded trials in chronic medical conditions. BMJ Medicine, 3, (doi: 10.1136/bmjmed-2023-000732)

Curtain, J. P., Talebi, A., McIntosh, A., McConnachie, A., O’Donnell, J., Welsh, P., Osmanska, J., Lee, M. M.Y., Sonecki, P., Akl, T., Seo, J., Gopinathan, V., Hurwitz, J., Thiagarajan, S., Pettit, S., Kalra, P. R., Patel, R. K., Mark, P. B., Lang, N. N., McMurray, J. J.V., Petrie, M. C., Gardner, R. S., Jhund, P. (2024) Measuring congestion with a non-invasive monitoring device in heart failure and haemodialysis: CONGEST-HF. European Journal of Heart Failure,

Lees, J. S., Fabian, J., Shlipak, M. G. (2024) Cystatin C should be routinely available for estimating kidney function. Current Opinion in Nephrology and Hypertension, 33, pp. 337-343. (doi: 10.1097/MNH.0000000000000980)

Madero, M., Chertow, G. M., Mark, P. B. (2024) SGLT2 inhibitor use in chronic kidney disease: supporting cardiovascular, kidney, and metabolic health. Kidney Medicine,

Butler, J. et al. (2024) Empagliflozin after acute myocardial infarction. New England Journal of Medicine, 390, pp. 1455-1466. (doi: 10.1056/NEJMoa2314051)

Cleland, J. G.F., Kalra, P. A., Pellicori, P., Graham, F. J., Foley, P. W.X., Squire, I. B., Cowburn, P. J., Seed, A., Clark, A. L., Szwejkowski, B., Banerjee, P., Cooke, J., Francis, M., Clifford, P., Wong, A., Petrie, C., McMurray, J. J.V., Thomson, E. A., Wetherall, K., Robertson, M., Ford, I., Kalra, P. R., the IRONMAN Study Group, (2024) Intravenous iron for heart failure, iron deficiency definitions, and clinical response: the IRONMAN trial. European Heart Journal, 45, pp. 1410-1426. (doi: 10.1093/eurheartj/ehae086)

Kosiborod, M. N. et al. (2024) Semaglutide in patients with obesity-related heart failure and type 2 diabetes. New England Journal of Medicine, 390, pp. 1394-1407. (doi: 10.1056/NEJMoa2313917)

Lang, N., Rankin, S., Elyan, B., Jones, R., Venugopal, B., Mark, P. B., Lees, J., Petrie, M., Lang, N. (2024) Cardiovascular eligibility criteria and adverse event reporting in combined immune checkpoint and VEGF inhibitors trials. JACC: CardioOncology, 6, pp. 267-279. (doi: 10.1016/j.jaccao.2023.12.010)

Glen, C., Morrow, A., Roditi, G., Hopkins, T., Macpherson, I., Stewart, P., Petrie, M. C., Berry, C., Epstein, F., Lang, N. N., Mangion, K. (2024) Cardiovascular sequalae of trastuzumab and anthracycline in long-term survivors of breast cancer. Heart, 110, pp. 650-656. (doi: 10.1136/heartjnl-2023-323437)

Mayne, K. J., Hanlon, P., Lees, J. (2024) Detecting and managing the patient with CKD in primary care: a review of the latest guidelines. Diabetes, Obesity and Metabolism,

Carberry, J., Petrie, M. C., Lee, M. M.Y., Brooksbank, K., Campbell, R. T., Good, R., Jhund, P. S., Kellman, P., Lang, N. N., Mangion, K., Mark, P. B., McConnachie, A., McMurray, J. J.V., Meyer, B., Orchard, V., Shaukat, A., Watkins, S., Welsh, P., Sattar, N., Berry, C., Docherty, K. F. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure,

Hernandez, A. F. et al. (2024) Effect of empagliflozin on heart failure outcomes after acute myocardial infarction: insights from the EMPACT-MI trial. Circulation, (doi: 10.1161/circulationaha.124.069217)

Stoumpos, S., van Rhijn, P., Mangion, K., Thomson, P. C., Mark, P. B. (2024) Arteriovenous fistula for haemodialysis as a predictor of de novo heart failure in kidney transplant recipients. Clinical Kidney Journal,

Sattar, N., Butler, J., Lee, M. M.Y., Harrington, J., Sharma, A., Zannad, F., Filippatos, G., Verma, S., Januzzi, J. L., Ferreira, J. P., Pocock, S. J., Pfarr, E., Ofstad, A. P., Brueckmann, M., Packer, M., Anker, S. D. (2024) Body mass index and cardiorenal outcomes in the EMPEROR-Preserved trial: principal findings and meta-analysis with the DELIVER trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3221)

Udell, J. A. et al. (2024) Left ventricular function, congestion, and effect of empagliflozin on heart failure risk after myocardial infarction. Journal of the American College of Cardiology, (doi: 10.1016/j.jacc.2024.03.405)

Jackson, A. M., Goland, S., Farhan, H. A., Yaseen, I. F., Prameswari, H. S., Böhm, M., Jhund, P. S., Maggioni, A. P., van der Meer, P., Sliwa, K., Bauersachs, J., Petrie, M. C. (2024) A novel score to predict left ventricular recovery in peripartum cardiomyopathy derived from the ESC EORP Peripartum Cardiomyopathy Registry. European Heart Journal, 45, pp. 1430-1439. (doi: 10.1093/eurheartj/ehad888)

Chen, D. C., Lu, K., Scherzer, R., Lees, J. S., Rutherford, E., Mark, P. B., Potok, O. A., Rifkin, D. E., Ix, J. H., Shlipak, M. G., Estrella, M. M. (2024) Cystatin C- and creatinine-based estimated GFR differences: prevalence and predictors in the UK Biobank. Kidney Medicine, 6, (doi: 10.1016/j.xkme.2024.100796)

Alharbi, A., Mullen, R.F., McClure, J.D., Miller, W.H. (2024) Effectiveness of Simulation-based Learning on Knowledge and Skill Acquisition and Retention among Nursing Students in Riyadh, Saudi Arabia: A Quasi-experimental Study.

Docherty, K. F., McMurray, J. J.V., Kalra, P., Cleland, J. G.F., Lang, N. N., Petrie, M. C., Robertson, M., Ford, I. (2024) Intravenous iron and SGLT2 inhibitors in iron-deficient patients with heart failure and reduced ejection fraction. ESC Heart Failure, (doi: 10.1002/ehf2.14742)

Kemi, O. J., Hoydal, M. A., Haram, P. M., Smith, G. L., Ellingsen, O., Koch, L. G., Britton, S. L., Wisloff, U. (2024) Inherited physical capacity: Widening divergence from young to adult to old. Annals of the New York Academy of Sciences, (doi: 10.1111/nyas.15130)

Del Vecchio, L., Girelli, D., Vinchi, F., Cozzolino, M., Elliott, S., Mark, P. B., Valenti, L., Qian, C., Guo, Q., Qian, Z.-M., Ciceri, P., Locatelli, F. (2024) Iron biology in chronic kidney disease: not just anaemia. Nephrology Dialysis Transplantation,

Savarese, G., Lindberg, F., Christodorescu, R. M., Ferrini, M., Kumler, T., Toutoutzas, K., Dattilo, G., Bayes-Genis, A., Moura, B., Amir, O., Petrie, M. C., Seferovic, P., Chioncel, O., Metra, M., Coats, A. J.S., Rosano, G. M.C. (2024) Physician perceptions, attitudes, and strategies towards implementing guideline-directed medical therapy in heart failure with reduced ejection fraction. A survey of the Heart Failure Association of the ESC and the ESC Council for Cardiology Practice. European Journal of Heart Failure, (doi: 10.1002/ejhf.3214)

Knigge, P., Lundberg, S., Strange, J. E., Malik, M. E., Nouhravesh, N., Wagner, A. K., Gislason, G., Fosbøl, E. L., Carlson, N., Zahir, D., Andersson, C., Butt, J. H., Jhund, P., Petrie, M. C., McMurray, J. J.V., Køber, L., Schou, M. (2024) Temporal trends in the initiation of dialysis among patients with heart failure with or without diabetes: a nationwide study from 2002 to 2016. Journal of the American Heart Association, 13, (doi: 10.1161/JAHA.123.032539)

Campbell, P., Rutten, F. H., Lee, M. M. Y., Hawkins, N. M., Petrie, M. C. (2024) Heart failure with preserved ejection fraction: Everything the clinician needs to know. Lancet, 403, pp. 1083-1092. (doi: 10.1016/S0140-6736(23)02756-3)

Cleland, J. G.F. (2024) Nature and magnitude of the benefits of dapagliflozin and empagliflozin for heart failure. Circulation, 149, pp. 839-842. (doi: 10.1161/circulationaha.123.068089)

Astrauskaite, G., Mohanan, S., Williamson, L., Boland, E., Huethorst, E., Kinegawa, R., Smith, G., Muellenbroich, C. (2024) Remote Focusing for 2-photon Microscopy to Follow Action Potential Propagation Transmurally in Acute Rabbit Cardiac Slices. (doi: 10.1117/12.3002956)

Shemilt, R., Sullivan, M.K., Hanlon, P., Jani, B., De La Mata, N., Rosales, B., Elyan, B.M.P., Hedley, J.A., Cutting, R.B., Wyld, M., McAllister, D.A., Webster, A.C., Mark, P.B., Lees, J.S. (2024) Sex differences in cancer outcomes across the range of eGFR. Nephrology Dialysis Transplantation, (doi: 10.1093/ndt/gfae059)

Kobayashi, M., Ferreira, J. P., Kevin, D., Bresso, E., Huttin, O., Bozec, E., Brunner La Rocca, H.-P., Delles, C., Clark, A. L., Edelmann, F., González, A., Heymans, S., Pellicori, P., Petutschnigg, J., Verdonschot, J. A.J., Rossignol, P., Cleland, J. G.F., Zannad, F., Girerd, N. (2024) Proteomic profiles of left atrial volume and its influence on response to spironolactone: findings from the HOMAGE trial and STANISLAS cohort. European Journal of Heart Failure,

Grobbee, D. E., Filippatos, G., Desai, N. R., Coats, A. J.S., Pinto, F., Rosano, G. M.C., Cleland, J., Kammerer, J., Ramirez de Arellano, A. (2024) Epidemiology and risk factors for hyperkalaemia in heart failure. ESC Heart Failure, (doi: 10.1002/ehf2.14661)

Cleland, J. G.F., Pellicori, P., Lakhal-Littleton, S. (2024) Low serum ferritin might predict incident heart failure but why and is it clinically useful? JACC: Heart Failure, 12, pp. 549-551. (doi: 10.1016/j.jchf.2023.12.012)

Freeman, M., Huethorst, E., Boland, E., Dunne, M., Burton, F., Denning, C., Myles, R., Smith, G. (2024) A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit. American Journal of Physiology: Heart and Circulatory Physiology, 326, pp. H735--H751. (doi: 10.1152/ajpheart.00657.2023)

Sliwa, K., van der Meer, P., Viljoen, C., Jackson, A. M., Petrie, M. C., Mebazaa, A., Hilfiker-Kleiner, D., Maggioni, A. P., Laroche, C., Regitz-Zagrosek, V., Tavazzi, L., Roos-Hesselink, J. W., Hamdan, R., Frogoudaki, A., Ibrahim, B., Farhan, H. A. F., Mbakwem, A., Seferovic, P., Böhm, M., Pieske, B., Johnson, M. R., Bauersachs, J. (2024) Socio-economic factors determine maternal and neonatal outcomes in women with peripartum cardiomyopathy: a study of the ESC EORP PPCM registry. International Journal of Cardiology, 398, (doi: 10.1016/j.ijcard.2023.131596)

Deo, S. V., Al-Kindi, S., Motairek, I., McAllister, D., Shah, A. S.V., Elgudin, Y. E., Gorodeski, E. Z., Virani, S., Petrie, M. C., Rajagopalan, S., Sattar, N. (2024) Impact of residential social deprivation on prediction of heart failure in patients with type 2 diabetes: External validation and recalibration of the WATCH-DM score using real world data. Circulation: Cardiovascular Quality and Outcomes, 17, pp. 267-276. (doi: 10.1161/circoutcomes.123.010166)

Adamson, W. E., Noyes, H., Johnson, P., Cooper, A., Monckton, D. G., Ogunsola, J., Beckett-Hill, G., Sullivan, M., Mark, P., Parekh, R. S., MacLeod, A. (2024) Phenome-wide analysis reveals epistatic associations between APOL1 variants and chronic kidney disease and multiple other disorders. EBioMedicine, 101, (doi: 10.1016/j.ebiom.2024.105000)

Balafa, O., Fernandez-Fernandez, B., Ortiz, A., Dounousi, E., Ekart, R., Ferro, C. J., Mark, P. B., Valdivielso, J. M., Del Vecchio, L., Mallamaci, F. (2024) Sex disparities in mortality and cardiovascular outcomes in chronic kidney disease. Clinical Kidney Journal, 17, (doi: 10.1093/ckj/sfae044)

Rudd, A. E., Horgan, G., Khan, H., Gamble, D. T., McGowan, J., Sood, A., McGeoch, R., Irving, J., Watt, J., Leslie, S. J., Petrie, M., Lang, C., Mills, N. L., Newby, D. E., Dawson, D. K. (2024) Cardiovascular and noncardiovascular prescribing and mortality after takotsubo comparison with myocardial infarction and general population. JACC: Advances, 3, (doi: 10.1016/j.jacadv.2023.100797)

Osmanska, J., Petrie, M. C., Campbell, R. T. (2024) Reply: subcutaneous furosemide patch: heart failure decongestion "from the comfort of your home" European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae015)

Mellbin, L. G., Bhatt, D. L., David, J.-P., Ekström, K., Petrie, M. C., Rasmussen, S., Vilsbøll, T. (2024) Semaglutide and cardiovascular outcomes by baseline HbA1c in diabetes: the SUSTAIN 6 and PIONEER 6 trials. European Heart Journal, 45, pp. 1371-1374. (doi: 10.1093/eurheartj/ehae028)

Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, (doi: 10.1038/s43856-024-00455-5)

Denicolò, S., Reinstadler, V., Keller, F., Thöni, S., Eder, S., Heerspink, H. J.L., Rosivall, L., Wiecek, A., Mark, P. B., Perco, P., Leierer, J., Kronbichler, A., Oberacher, H., Mayer, G. (2024) Non-adherence to antidiabetic and cardiovascular medication as assessed by LC-MS/MS in urine and its association with kidney and cardiovascular outcomes in type 2 diabetes mellitus. Diabetologia,

Loughrey, C. et al. (2024) A novel ryanodine receptor 2 inhibitor, M201-A, enhances natriuresis, renal function and lusi-inotropic action: Pre-clinical and phase I study. British Journal of Pharmacology,

Pellicori, P., Felker, G. M., Cleland, J. G.F. (2024) Reply to ‘Vasodilators in congestive heart failure: The perfect weapon aiming just off the target?’ European Journal of Heart Failure, 26, pp. 528-528. (doi: 10.1002/ejhf.3159)

Heerspink, H. J.L., Provenzano, M., Vart, P., Jongs, N., Correa-Rotter, R., Rossing, P., Mark, P. B., Pecoits-Filho, R., McMurray, J. J.V., Langkilde, A. M., Wheeler, D. C., Toto, R. B., Chertow, G. M. (2024) Dapagliflozin and blood pressure in patients with chronic kidney disease and albuminuria. American Heart Journal, (doi: 10.1016/j.ahj.2024.02.006)

Friedman, D. J., Olivas-Martinez, A., Dalgaard, F., Fudim, M., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Gold, M. R., Kutyifa, V., Linde, C., Tang, A. S., Ali-Ahmed, F., Inoue, L. Y.T., Sanders, G. D., Al-Khatib, S. M. (2024) Relationship between sex, body size, and cardiac resynchronization therapy benefit: a patient level meta-analysis of randomized controlled trials. Heart Rhythm, (doi: 10.1016/j.hrthm.2024.01.058)

UK HFpEF Collaborative Group, , , (2024) Rationale and design of the United Kingdom Heart Failure with Preserved Ejection Fraction Registry. Heart, 110, pp. 359-365. (doi: 10.1136/heartjnl-2023-323049)

Black, N., Bradley, J., Lewis, G., Lagan, J., Orsborne, C., Soltani, F., Farrant, J. P., McDonagh, T., Schmitt, M., Cavalcante, J. L., Ugander, M., Butler, J., Petrie, M. C., Miller, C. A., Schelbert, E. B. (2024) Development and validation of imaging-free myocardial fibrosis prediction models, association with outcomes, and sample size estimation for phase 3 trials. medRxiv, (doi: 10.1101/2024.02.07.24302443)

Lakhal-Littleton, S., Cleland, J. G. F. (2024) Iron deficiency and supplementation in heart failure. Nature Reviews Cardiology, (doi: 10.1038/s41569-024-00988-1)

Goldie, F. C., Lee, M. M. Y., Coats, C. J., Nordin, S. (2024) Advances in multi-modality imaging in hypertrophic cardiomyopathy. Journal of Clinical Medicine, 13, (doi: 10.3390/jcm13030842)

Butt, J. H., McDowell, K., Kondo, T., Desai, A. S., Lefkowitz, M. P., Packer, M., Petrie, M. C., Pfeffer, M. A., Rouleau, J. L., Vaduganathan, M., Zile, M. R., Jhund, P. S., Køber, L., Solomon, S., McMurray, J. J.V. (2024) Heart failure with preserved ejection fraction, red cell distribution width, and sacubitril/valsartan. ESC Heart Failure, 11, pp. 65-77. (doi: 10.1002/ehf2.14558)

Pellicori, P., Cleland, J. G.F. (2024) Atrial myopathy and heart failure with preserved ejection fraction: When a label does more harm than good? European Journal of Heart Failure, (doi: 10.1002/ejhf.3148)

Omerovic, E., Petrie, M., Redfors, B., Fremes, S., Murphy, G., Marquis-Gravel, G., Lansky, A., Velazquez, E., Perera, D., Reid, C., Smith, J., van der Meer, P., Lipsic, E., Juni, P., McMurray, J., Bauersachs, J., Køber, L., Rouleau, J. L., Doenst, T. (2024) Pragmatic randomized controlled trials: strengthening the concept through a robust international collaborative network: PRIME-9-pragmatic research and innovation through multinational experimentation. Trials, 25, (doi: 10.1186/s13063-024-07935-y)

Petrie, M. C., Rouleau, J. L., Claggett, B., Jering, K., van der Meer, P., Køber, L., Miao, Z. M., Lewis, E., Granger, C., De Pasqulae, C. G., Mann, D., Steg, P. G., Maggioni, A., Amir, O., Lefkowitz, M., Braunwald, E., Solomon, S. D., McMurray, J. J. V., Pfeffer, M. A. (2024) Pulmonary congestion and left ventricular dysfunction after myocardial infarction: insights from the PARADISE-MI trial. Circulation, 149, pp. 335-38. (doi: 10.1161/CIRCULATIONAHA.123.066163)

McCaffrey, C., McClure, J., Singh, S., Melville, C. A. (2024) Exploring the relationship between sleep and aggression in adolescents: a cross-sectional study using the UK Millennium Cohort Study. Clinical Child Psychology and Psychiatry, (doi: 10.1177/13591045231225824)

Kosiborod, M. N., Verma, S., Borlaug, B. A., Butler, J., Davies, M. J., Jon Jensen, T., Rasmussen, S., Erlang Marstrand, P., Petrie, M. C., Shah, S. J., Ito, H., Schou, M., Melenovský, V., Abhayaratna, W., Kitzman, D. W., STEP-HFpEF Trial Committees and Investigators, (2024) Effects of semaglutide on symptoms, function, and quality of life in patients with heart failure with preserved ejection fraction and obesity: a prespecified analysis of the STEP-HFpEF trial. Circulation, 149, pp. 204-216. (doi: 10.1161/circulationaha.123.067505)

Cuthbert, J. J., Brown, O. I., Pellicori, P., Dobbs, K., Bulemfu, J., Kazmi, S., Sokoreli, I., Pauws, S. C., Riistama, J. M., Cleland, J. G.F., Clark, A. L. (2024) Medicines optimization prior to discharge in patients admitted to hospital with heart failure. ESC Heart Failure, (doi: 10.1002/ehf2.14638)

Pellicori, P., Hunter, D., Khin, H. H. E., Cleland, J. G.F. (2024) How to diagnose and treat venous congestion in heart failure. European Heart Journal, (doi: 10.1093/eurheartj/ehad883)

Pellicori, P., Cleland, J. G.F. (2024) Atrial myopathy and HFpEF - when a label does more harm than good. European Journal of Heart Failure,

Sidik, N. P., Stanley, B., Sykes, R., Morrow, A. J., Bradley, C. P., Mcdermott, M., Ford, T., Roditi, G., Hargreaves, A., Stobo, D., Adams, J., Byrne, J., Mahrous, A., Young, R., Carrick, D., McGeoch, R., Corcoran, D., Lang, N. N., Heggie, R., Wu, O., McEntegart, M. B., McConnachie, A., Berry, C. (2024) Invasive endotyping in patients with angina and no obstructive coronary artery disease: a randomized controlled trial. Circulation, 149, pp. 7-23. (doi: 10.1161/CIRCULATIONAHA.123.064751)

Osmanska, J., Brooksbank, K., Docherty, K. F., Robertson, S., Wetherall, K., McConnachie, A., Hu, J., Gardner, R. S., Clark, A. L., Squire, I. B., Kalra, P. R., Jhund, P. S., Muntendam, P., McMurray, J. J.V., Petrie, M. C., Campbell, R. T. (2024) A novel, small-volume subcutaneous furosemide formulation delivered by an abdominal patch infusor device in patients with heart failure: results of two phase I studies. European Heart Journal: Cardiovascular Pharmacotherapy, 10, pp. 35-44. (doi: 10.1093/ehjcvp/pvad073)

Zeitler, E. P., Dalgaard, F., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Friedman, D. J., Gold, M. R., Kutyifa, V., Linde, C., Tang, A. S., Olivas-Martinez, A., Inoue, L. Y.T., Sanders, G. D., Al-Khatib, S. M. (2024) Benefit of cardiac resynchronization therapy among older patients: A patient-level meta-analysis. American Heart Journal, 267, pp. 81-90. (doi: 10.1016/j.ahj.2023.11.002)

Cleland, J. G. F. (2024) Defining iron deficiency in patients with heart failure. Nature Reviews Cardiology, 21, pp. 1-2. (doi: 10.1038/s41569-023-00951-6)

Lee, M. M.Y., Kondo, T., Campbell, R. T., Petrie, M. C., Sattar, N., Solomon, S. D., Vaduganathan, M., Jhund, P. S., McMurray, J. J.V. (2024) Effects of Renin-Angiotensin system blockers on outcomes from COVID-19: a systematic review and meta-analysis of randomised controlled trials. European Heart Journal: Cardiovascular Pharmacotherapy, 10, pp. 68-80. (doi: 10.1093/ehjcvp/pvad067)

Chivardi, C. et al. (2024) Percutaneous revascularization for ischemic left ventricular dysfunction: Cost-effectiveness analysis of the REVIVED-BCIS2 trial. Circulation: Cardiovascular Quality and Outcomes, 17, (doi: 10.1161/circoutcomes.123.010533)

Monzo, L., Girerd, N., Ferreira, J. P., Lamiral, Z., Anker, S. D., Cleland, J. G. F., Kondo, T., McMurray, J. J. V., Lam, C. S. P., Mehra, M. R., van Veldhuisen, D. J., Greenberg, B., Zannad, F. (2024) High risk of stroke in patients with worsening heart failure, reduced ejection fraction, coronary heart disease and sinus rhythm: risk prediction score analysis from the COMMANDER-HF trial. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2023.11.020)

2023

Lee, M. M.Y., Lean, M. E.J., Sattar, N., Petrie, M. C. (2023) Appetite and its regulation: Are there palatable interventions for heart failure? Current Heart Failure Reports, 21, pp. 1-4. (doi: 10.1007/s11897-023-00637-7)

Kosiborod, M. N., Borlaug, B. A., Petrie, M. C. (2023) Semaglutide and heart failure with preserved ejection fraction and obesity. Reply. New England Journal of Medicine, 389, pp. 2398-2399. (doi: 10.1056/NEJMc2312296)

Glen, C., Adam, S., Coats, C. J., Lang, N. N. (2023) Reply: Cardiotoxicity of BRAF/MEK inhibitors according to HFA/ICOS cardiotoxicity risk category. JACC: CardioOncology, 5, pp. 850. (doi: 10.1016/j.jaccao.2023.10.003)

Mayne, K. J. et al. (2023) Effects of empagliflozin on fluid overload, weight and blood pressure in chronic kidney disease. Journal of the American Society of Nephrology, (doi: 10.1681/ASN.0000000000000271)

Welsh, P., Kimenai, D. M., Shah, A. S.V., Gadd, D. A., Marioni, R. E., Woodward, M., Sudlow, C. L.M., Campbell, A., Cleland, J. G.F., Pellicori, P., Hayward, C., Mills, N. L., Sattar, N. (2023) Multiple cardiac biomarkers to improve prediction of cardiovascular events: findings from the Generation Scotland Scottish Family Health Study. Clinical Chemistry, 70, pp. 403-413. (doi: 10.1093/clinchem/hvad205)

Lee, M. M.Y., Masri, A. (2023) Correction to: Differentiating cardiac troponin levels during cardiac myosin inhibition or cardiac myosin activation treatments: drug effect or the canary in the coal mine? Current Heart Failure Reports, (doi: 10.1007/s11897-023-00639-5)

Connelly, P., Osmanska, J., Lee, M. M.Y., Delles, C., McEntegart, M. B., Byrne, J. (2023) A case report of myocardial infarction in a young transgender man with testosterone therapy? raising awareness on healthcare issues in the transgender community and a call for further research. European Heart Journal: Case Reports, 7, (doi: 10.1093/ehjcr/ytad562)

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2022

Lithgow, H., Johnston, L., Ho, F. K., Celis-Morales, C., Cobley, J., Raastad, T., Hunter, A. M., Lees, J. S., Mark, P. B., Quinn, T. J., Gray, S. R. (2022) Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle-damaging resistance exercise in young and older adults—the TAKEOVER study. Trials, 23, (doi: 10.1186/s13063-022-06937-y)

Kalra, P. R., Cleland, J. G.F., Petrie, M. C., Thomson, E. A., Kalra, P. A., Squire, I. B., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Foley, P. W.X., Graham, F. J., Japp, A. G., Lane, R. E., Lang, N. N., Ludman, A. J., Macdougall, I. C., Pellicori, P., Ray, R., Robertson, M., Seed, A., Ford, I. (2022) Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial. Lancet, 400, pp. 2199-2209. (doi: 10.1016/S0140-6736(22)02083-9)

McGettrick, M., Dormand, H., Brewis, M., Johnson, M. K., Lang, N. N., Church, A. C. (2022) Cardiac geometry, as assessed by cardiac magnetic resonance, can differentiate subtypes of chronic thromboembolic pulmonary vascular disease. Frontiers in Cardiovascular Medicine, 9, (doi: 10.3389/fcvm.2022.1004169)

Mehran, R., Steg, P. G., Pfeffer, M. A., Jering, K., Claggett, B., Lewis, E. F., Granger, C., Køber, L., Maggioni, A., Mann, D. L., McMurray, J. J.V., Rouleau, J.-L., Solomon, S. D., Ducrocq, G., Berwanger, O., De Pasquale, C. G., Landmesser, U., Petrie, M., Leng, D. S. K., van der Meer, P., Lefkowitz, M., Zhou, Y., Braunwald, E. (2022) The effects of angiotensin receptor-neprilysin inhibition on major coronary events in patients with acute myocardial infarction: insights from the PARADISE-MI trial. Circulation, 146, pp. 1749-1757. (doi: 10.1161/CIRCULATIONAHA.122.060841)

Bhandari, S., Mehta, S., Khwaja, A., Cleland, J. G.F., Ives, N., Brettell, E., Chadburn, M., Cockwell, P. (2022) Renin-angiotensin system inhibition in advanced chronic kidney disease. New England Journal of Medicine, 387, pp. 2021-2032. (doi: 10.1056/NEJMoa2210639)

Saxena, P., Myles, R. C., Smith, G. L., Workman, A. J. (2022) Adrenoceptor sub-type involvement in Ca2+ current stimulation by noradrenaline in human and rabbit atrial myocytes. Pflügers Archiv European Journal of Physiology, 474, pp. 1311-1321. (doi: 10.1007/s00424-022-02746-z)

Lees, J. S., Shlipak, M. G. (2022) Age-adapted eGFR thresholds underestimate the risks beyond kidney failure associated with CKD in older populations. Journal of the American Geriatrics Society, 70, pp. 3660-3664. (doi: 10.1111/jgs.18046)

Gregers, M. C. T., Schou, M., Jensen, M. T., Jensen, J., Petrie, M. C., Vilsbøll, T., Goetze, J. P., Rossing, P., Jørgensen, P. G. (2022) Diagnostic and prognostic value of the electrocardiogram in stable outpatients with type 2 diabetes. Scandinavian Cardiovascular Journal, 56, pp. 256-263. (doi: 10.1080/14017431.2022.2095435)

Monzo, L., Ferreira, J. P., Cleland, J. G.F., Pellicori, P., Mariottoni, B., Hazebroek, M. R., Collier, T. J., Cuthbert, J. J., Pieske, B., Petutschnigg, J., Ahmed, F. Z., Girerd, N., Clark, A. L., Cosmi, F., Staessen, J. A., Heymans, S., Rossignol, P., Zannad, F. (2022) Dyskalemia in people at increased risk for heart failure: findings from the heart ‘OMics’ in AGEing (HOMAGE) trial. ESC Heart Failure, 9, pp. 4352-4357. (doi: 10.1002/ehf2.14086)

Pugliese, N. R., Pellicori, P., Filidei, F., De Biase, N., Maffia, P., Guzik, T. J., Masi, S., Taddei, S., Cleland, J. G.F. (2022) Inflammatory pathways in heart failure with preserved left ventricular ejection fraction: implications for future interventions. Cardiovascular Research, 118, pp. 3536-3555. (doi: 10.1093/cvr/cvac133)

Bracun, V., van Essen, B., Voors, A. A., van Veldhuisen, D. J., Dickstein, K., Zannad, F., Metra, M., Anker, S., Samani, N. J., Ponikowski, P., Filippatos, G., Cleland, J. G.F., Lang, C. C., Ng, L. L., Shi, C., de Wit, S., About Msallem, J. P., Meijers, W. C., Klip, I. T., van der Meer, P., de Boer, R. A. (2022) Insulin‐like growth factor binding protein 7 (IGFBP7), a link between heart failure and senescence. ESC Heart Failure, 9, pp. 4167-4176. (doi: 10.1002/ehf2.14120)

Mark, P. B., Mangion, K., Rankin, A. J., Rutherford, E., Lang, N. N., Petrie, M. C., Stoumpos, S., Patel, R. K. (2022) Left ventricular dysfunction with preserved ejection fraction: the most common left ventricular disorder in chronic kidney disease patients. Clinical Kidney Journal, 15, pp. 2186-2199. (doi: 10.1093/ckj/sfac146)

de Wit, S., Glen, C., de Boer, R. A., Lang, N. N. (2022) Mechanisms shared between cancer, heart failure, and targeted anti-cancer therapies. Cardiovascular Research, 118, pp. 3451-3466. (doi: 10.1093/cvr/cvac132)

Kalra, P. R., Cleland, J. G. F., Petrie, M. C., Ahmed, F. Z., Foley, P. W. X., Kalra, P. A., Lang, N. N., Lane, R. E., Macdougall, I. C., Pellicori, P., Pope, M. T. B., Robertson, M., Squire, I. B., Thomson, E. A., Ford, I. (2022) Rationale and design of a randomised trial of intravenous iron in patients with heart failure. Heart, 108, pp. 1979-1985. (doi: 10.1136/heartjnl-2022-321304)

Mark, P. B., Sattar, N. (2022) Implementation, not hesitation, for SGLT2 inhibition as foundational therapy for chronic kidney disease. Lancet, 400, pp. 1745-1747. (doi: 10.1016/S0140-6736(22)02164-X)

Tromp, J., Bauer, D., Claggett, B. L., Frost, M., Iversen, M. B., Prasad, N., Petrie, M. C., Larson, M. G., Ezekowitz, J. A., Solomon, S. D. (2022) A formal validation of a deep learning-based automated workflow for the interpretation of the echocardiogram. Nature Communications, 13, (doi: 10.1038/s41467-022-34245-1)

Kondo, T., Abdul-Rahim, A. H., Talebi, A., Abraham, W. T., Desai, A. S., Dickstein, K., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Packer, M., Petrie, M., Ponikowski, P., Rouleau, J. L., Sabatine, M. S., Swedberg, K., Zile, M. R., Solomon, S. D., Jhund, P. S., McMurray, J. J.V. (2022) Predicting stroke in heart failure and reduced ejection fraction without atrial fibrillation. European Heart Journal, 43, pp. 4469-4479. (doi: 10.1093/eurheartj/ehac487)

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Mayne, K. J., Shemilt, R., Keane, D. F., Lees, J. S., Mark, P. B., Herrington, W. G. (2022) Bioimpedance indices of fluid overload and cardiorenal outcomes in heart failure and chronic kidney disease: a systematic review. Journal of Cardiac Failure, 28, pp. 1628-1641. (doi: 10.1016/j.cardfail.2022.08.005)

Pellicori, P., Kalra, P. R., Clark, A. L., Friday, J., Cleland, J. G. F. (2022) Chronic kidney disease (CKD) and CKD-ism in heart failure – what a mess! European Journal of Heart Failure, 24, pp. 2196-2198. (doi: 10.1002/ejhf.2696)

Inciardi, R. M., Pagnesi, M., Lombardi, C. M., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G. S., Lang, C. C., Ng, L. L., Pellicori, P., Ponikowski, P., Samani, N. J., Zannad, F., van Veldhuisen, D. J., Solomon, S. D., Voors, A. A., Metra, M. (2022) Clinical implications of left atrial changes after optimization of medical therapy in patients with heart failure. European Journal of Heart Failure, 24, pp. 2131-2139. (doi: 10.1002/ejhf.2593)

Lachaud, Q., Aziz, M. H. N., Burton, F. L., Macquaide, N., Myles, R. C., Simitev, R. D., Smith, G. L. (2022) Electrophysiological heterogeneity in large populations of rabbit ventricular cardiomyocytes. Cardiovascular Research, 118, pp. 3112-3125. (doi: 10.1093/cvr/cvab375)

Harrington, J., Udell, J. A., Jones, W. S., Anker, S. D., Bhatt, D. L., Petrie, M. C., Vedin, O., Sumin, M., Zwiener, I., Hernandez, A. F., Butler, J. (2022) Empagliflozin in patients post myocardial infarction rationale and design of the EMPACT-MI trial. American Heart Journal, 253, pp. 86-98. (doi: 10.1016/j.ahj.2022.05.010)

Arulmurugananthavadivel, A., Holt, A., Parveen, S., Lamberts, M., Gislason, G. H., Torp-Pedersen, C., Madelaire, C., Andersson, C., Zahir, D., Butt, J. H., Petrie, M. C., McMurray, J., Fosbol, E. L., Kober, L., Schou, M. (2022) Importance of diagnostic setting in determining mortality in patients with new-onset heart failure: temporal trends in Denmark 1997–2017. European Heart Journal: Quality of Care and Clinical Outcomes, 8, pp. 750-760. (doi: 10.1093/ehjqcco/qcab073)

Seckin, M., Johnston, B., Petrie, M. C., Stewart, S., Chan, Y.-K. (2022) Characteristics of symptoms and symptom change across different heart failure subtypes: a sex-stratified analysis. European Journal of Cardiovascular Nursing, (doi: 10.1093/eurjcn/zvac099)

Salah, H. M., Goldberg, L. R., Molinger, J., Felker, G. M., Applefeld, W., Rassaf, T., Tedford, R. J., Mirro, M., Cleland, J. G.F., Fudim, M. (2022) Diaphragmatic function in cardiovascular disease: JACC review topic of the week. Journal of the American College of Cardiology, 80, pp. 1647-1659. (doi: 10.1016/j.jacc.2022.08.760)

Bruegmann, T., Smith, G. L., Lehnart, S. E. (2022) Editorial: Cardiac optogenetics: Using light to observe and excite the heart. Frontiers in Physiology, 13, (doi: 10.3389/fphys.2022.1031062)

Lota, A. S. et al. (2022) Genetic architecture of acute myocarditis and the overlap with inherited cardiomyopathy. Circulation, 146, pp. 1123-1134. (doi: 10.1161/CIRCULATIONAHA.121.058457)

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Garred, C. H., Zahir, D., Butt, J. H., Ravn, P. B., Bruhn, J., Gislason, G. H., Fosbøl, E. L., Torp‐Pedersen, C., Petrie, M. C., McMurray, J. J.V., Køber, L., Schou, M. (2022) Adherence and discontinuation of optimal heart failure therapies according to age: a Danish nationwide study. Journal of the American Heart Association, 11, (doi: 10.1161/JAHA.122.026187)

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2021

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Graham, F. J., Pellicori, P., Cleland, J. G.F., Clark, A. L. (2021) Reply to the letter regarding the article 'Natural history and prognostic significance of iron deficiency and anaemia in ambulatory patients with chronic heart failure' European Journal of Heart Failure, 23, pp. 1800-1801. (doi: 10.1002/ejhf.2304)

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Castrichini, M., Nuzzi, V., Sinagra, G., Cleland, J., Pellicori, P. (2021) Use of social media by cardiovascular health care professionals: is patient privacy respected? JACC: Cardiovascular Imaging, 14, pp. 1680-1682. (doi: 10.1016/j.jcmg.2021.02.012)

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Lee, M. M.Y., McMurray, J. J.V., Jhund, P. S., Petrie, M. C., Sattar, N. (2021) Response by Lee et al to letter regarding article, "Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)" Circulation, 144, pp. e40. (doi: 10.1161/CIRCULATIONAHA.121.055067)

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Bistola, V., Simitsis, P., Parissis, J., Ouwerkerk, W., van Veldhuisen, D. J., Cleland, J. G., Anker, S. D., Samani, N. J., Metra, M., Zannad, F., Polyzogopoulou, E., Keramida, K., Farmakis, D., Voors, A. A., Filippatos, G. (2021) Association between up-titration of medical therapy and total hospitalizations and mortality in patients with recent worsening heart failure across the ejection fraction spectrum. European Journal of Heart Failure, 23, pp. 1170-1181. (doi: 10.1002/ejhf.2219)

Kelly, D. M., Ademi, Z., Doehner, W., Lip, G. Y.H., Mark, P., Toyoda, K., Wong, C. X., Sarnak, M., Cheung, M., Herzog, C. A., Johansen, K. L., Reinecke, H., Sood, M. M. (2021) Chronic kidney disease and cerebrovascular disease: consensus and guidance from a KDIGO controversies conference. Stroke, 52, pp. e328-e346. (doi: 10.1161/STROKEAHA.120.029680)

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Lang, N. N., Ahmad, F. A., Cleland, J. G., O'Connor, C. M., Teerlink, J. R., Voors, A. A., Taubel, J., Hodes, A. R., Anwar, M., Karra, R., Sakata, Y., Ishihara, S., Senior, R., Khemka, A., Prasad, N. G., DeSouza, M. M., Seiffert, D., Ye, J. Y., Kessler, P. D., Borentain, M., Solomon, S. D., Felker, G. M., McMurray, J. J.V. (2021) Haemodynamic effects of the nitroxyl donor cimlanod (BMS-986231) in chronic heart failure: a randomized trial. European Journal of Heart Failure, 23, pp. 1147-1155. (doi: 10.1002/ejhf.2138)

Jhund, P. S., Petrie, M. C., Robertson, M., Mark, P. B., MacDonald, M. R., Connolly, E., Anker, S. D., Bhandari, S., Farrington, K., Kalra, P. A., Wheeler, D. C., Tomson, C. R.V., Ford, I., McMurray, J. J.V., Macdougall, I. C. (2021) Heart failure hospitalization in adults receiving maintenance hemodialysis and effect of intravenous iron therapy: A report from PIVOTAL. JACC: Heart Failure, 9, pp. 518-527. (doi: 10.1016/j.jchf.2021.04.005)

Halliday, B. P., Vazir, A., Owen, R., Gregson, J., Wassall, R., Lota, A. S., Khalique, Z., Tayal, U., Jones, R. E., Hammersley, D., Pantazis, A., Baksi, A. J., Rosen, S., Pennell, D. J., Cowie, M. R., Cleland, J. G.F., Prasad, S. K. (2021) Heart rate as a marker of relapse during withdrawal of therapy in recovered dilated cardiomyopathy. JACC: Heart Failure, 9, pp. 509-517. (doi: 10.1016/j.jchf.2021.03.010)

Gupta, P., Voors, A. A., Patel, P., Lane, D., Anker, S. D., Cleland, J. G.F., Dickstein, K., Filippatos, G., Lang, C.C., Veldhuisen, D. J., Metra, M., Zannad, F., Samani, N. J., Jones, D. J.L., Squire, I. B., Ng, L. L. (2021) Non-adherence to heart failure medications predicts clinical outcomes: assessment in a single spot urine sample by liquid chromatography-tandem mass spectrometry (results of a prospective multicentre study) European Journal of Heart Failure, 23, pp. 1182-1190. (doi: 10.1002/ejhf.2160)

Diaz-Navarro, R., Urrútia, G., Cleland, J. G.F., Poloni, D., Villagran, F., Acosta-Dighero, R., Bangdiwala, S. I., Rada, G., Madrid, E. (2021) Stem cell therapy for dilated cardiomyopathy. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.cd013433.pub2)

Markousis-Mavrogenis, G., Tromp, J., Mentz, R. J., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2021) The additive prognostic value of serial plasma interleukin-6 levels over changes in brain natriuretic peptide in patients with acute heart failure. Journal of Cardiac Failure, 27, pp. 808-811. (doi: 10.1016/j.cardfail.2021.01.008)

Holmes, A. P., Saxena, P., Kabir, S. N., O'Shea, C., Kuhlmann, S. M., Gupta, S., Fobian, D., Apicella, C., O'Reilly, M., Syeda, F., Reyat, J. S., Smith, G. L., Workman, A. J., Pavlovic, D., Fabritz, L., Kirchhof, P. (2021) The atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone. Heart Rhythm, 18, pp. 1212-1220. (doi: 10.1016/j.hrthm.2021.03.016)

Rush, C. J., Cleland, J. G.F., Veldtman, G. (2021) The emerging burden of heart failure in adults with congenital heart disease. International Journal of Cardiology Congenital Heart Disease, 4, (doi: 10.1016/j.ijcchd.2021.100171)

Pellicori, P., Fitchett, D., Kosiborod, M. N., Ofstad, A. P., Seman, L., Zinman, B., Zwiener, I., Wanner, C., George, J., Inzucchi, S. E., Testani, J. M., Cleland, J. G.F. (2021) Use of diuretics and outcomes in patients with type 2 diabetes: findings from the EMPA-REG OUTCOME trial. European Journal of Heart Failure, 23, pp. 1085-1093. (doi: 10.1002/ejhf.2220)

Lees, J. S., Mark, P. B., Witham, M. D. (2021) Vitamin K and vascular calcification. Current Opinion in Nephrology and Hypertension, 30, pp. 430-436. (doi: 10.1097/MNH.0000000000000712)

Edy, E., Rankin, A. J., Lees, J. S., Hall Barrientos, P., Woodward, R., Stoumpos, S., Koktzoglou, I., Edelman, R. R., Radjenovic, A., Mark, P. B., Roditi, G. H. (2021) Cardiovascular magnetic resonance for the detection of descending thoracic aorta calcification in patients with end-stage renal disease. Journal of Cardiovascular Magnetic Resonance, 23, (doi: 10.1186/s12968-021-00769-6)

Cleland, J. G.F., Pfeffer, M. A., Clark, A. L., Januzzi, J. L., McMurray, J. J.V., Mueller, C., Pellicori, P., Richards, M., Teerlink, J. R., Zannad, F., Bauersachs, J. (2021) The struggle towards a universal definition of heart failure—how to proceed? European Heart Journal, 42, pp. 2331-2343. (doi: 10.1093/eurheartj/ehab082)

Chowdhury, T. A., Wahba, M., Mallik, R., Peracha, J., Patel, D., De, P., Fogarty, D., Frankel, A., Karalliedde, J., Mark, P. B., Montero, R. M., Pokrajac, A., Zac Varghese, S., Bain, S. C., Dasgupta, I., Banerjee, D., Winocour, P., Sharif, A. (2021) Association of british clinical diabetologists and renal association guidelines on the detection and management of diabetes post solid organ transplantation. Diabetic Medicine, 38, (doi: 10.1111/dme.14523)

Butt, J. H., Docherty, K. F., Petrie, M. C., Schou, M., Kosiborod, M. N., O’Meara, E., Katova, T., Ljungman, C. E.A., Diez, M., Ogunniyi, M. O., Langkilde, A. M., Sjöstrand, M., Lindholm, D., Bengtsson, O., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Jhund, P. S., McMurray, J. J.V., Køber, L. (2021) Efficacy and safety of dapagliflozin in men and women with heart failure with reduced ejection fraction: results from the DAPA-HF trial. JAMA Cardiology, 6, pp. 678-689. (doi: 10.1001/jamacardio.2021.0379)

Lees, J. S., Mark, P. B. (2021) Fruit for thought: lifestyle interventions to reduce the risk of future chronic kidney disease. Nephrology Dialysis Transplantation, 36, pp. 963-965. (doi: 10.1093/ndt/gfaa266)

Sierpinski, R., Josiak, K., Suchocki, T., Wojtas‐Polc, K., Mazur, G., Butrym, A., Rozentryt, P., Meer, P., Comin‐Colet, J., Haehling, S., Kosmala, W., Przewlocka‐Kosmala, M., Banasiak, W., Nowak, J., Voors, A. A., Anker, S. D., Cleland, J. G.F., Ponikowski, P., Jankowska, E. A. (2021) High soluble transferrin receptor in patients with heart failure: a measure of iron deficiency and a strong predictor of mortality. European Journal of Heart Failure, 23, pp. 919-932. (doi: 10.1002/ejhf.2036)

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Pandhi, P., Streng, K. W., Anker, S. D., Cleland, J. G., Damman, K., Dickstein, K., Pellicori, P., Lang, C. C., Ng, L., Samani, N. J., Metra, M., Rossignol, P., Filippatos, G., van Veldhuisen, D. J., Voors, A. A., ter Maaten, J. M. (2021) The value of spot urinary creatinine as a marker of muscle wasting in patients with new-onset or worsening heart failure. Journal of Cachexia, Sarcopenia and Muscle, 12, pp. 555-567. (doi: 10.1002/jcsm.12690)

Maznyczka, A. M., Carrick, D., Oldroyd, K. G., James-Rae, G., McCartney, P., Greenwood, J. P., Good, R., McEntegart, M., Eteiba, H., Lindsay, M., Cotton, J. M., Petrie, M. C., Berry, C. (2021) Thermodilution-derived temperature recovery time, a novel predictor of microvascular reperfusion and prognosis after myocardial infarction. EuroIntervention, 17, pp. 220-228. (doi: 10.4244/EIJ-D-19-00904)

Bowman, P. R.T., Smith, G. L., Gould, G. W. (2021) Run for your life: can exercise be used to effectively target GLUT4 in diabetic cardiac disease? PeerJ, 9, (doi: 10.7717/peerj.11485)

Jhund, P. S., Ponikowski, P., Docherty, K. F., Gasparyan, S. B., Böhm, M., Chang, C.-E., Desai, A. S., Howlett, J., Kitakaze, M., Petrie, M. C., Verma, S., Bengtsson, O., Langkilde, A.-M., Sjöstrand, M., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Sabatine, M. S., Solomon, S. D., McMurray, J. J.V. (2021) Dapagliflozin and recurrent heart failure hospitalizations in heart failure with reduced ejection fraction: an analysis of DAPA-HF. Circulation, 143, pp. 1962-1972. (doi: 10.1161/CIRCULATIONAHA.121.053659)

Wang, L., Myles, R. C., Lee, I.-J., Bers, D. M., Ripplinger, C. M. (2021) Role of reduced sarco-endoplasmic reticulum Ca2+-ATPase function on sarcoplasmic reticulum Ca2+ alternans in the intact rabbit heart. Frontiers in Physiology, 12, (doi: 10.3389/fphys.2021.656516)

Emmens, J. E., Jia, C., Ng, L. L., van Veldhuisen, D. J., Dickstein, K., Anker, S. D., Lang, C. C., Filippatos, G., Cleland, J. G.F., Metra, M., Voors, A. A., de Boer, R. A., Tietge, U. J.F. (2021) Impaired high-density lipoprotein function in patients with heart failure. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.120.019123)

Rossitto, G., Maiolino, G., Lerco, S., Ceolotto, G., Blackburn, G., Mary, S., Antonelli, G., Berton, C., Bisogni, V., Cesari, M., Seccia, T. M., Lenzini, L., Pinato, A., Montezano, A., Touyz, R. M., Petrie, M. C., Daly, R., Welsh, P., Plebani, M., Rossi, G. P., Delles, C. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117, pp. 1372-1381. (doi: 10.1093/cvr/cvaa205)

Lee, M. M.Y., Ghouri, N., McGuire, D. K., Rutter, M. K., Sattar, N. (2021) Meta-analyses of results from randomized outcome trials comparing cardiovascular effects of SGLT2i and GLP-1RA in Asian vs. White patients with and without type 2 diabetes. Diabetes Care, 44, pp. 1236-1241. (doi: 10.2337/dc20-3007)

Wolsk, E., Kaye, D. M., Komtebedde, J., Shah, S. J., Borlaug, B. A., Burkhoff, D., Kitzman, D. W., Cleland, J. G., Hasenfuß, G., Hassager, C., Møller, J. E., Gustafsson, F. (2021) Determinants and consequences of heart rate and stroke volume response to exercise in patients with heart failure and preserved ejection fraction. European Journal of Heart Failure, 23, pp. 754-764. (doi: 10.1002/ejhf.2146)

Tromp, J., Ouwerkerk, W., Cleland, J. G.F., Angermann, C. E., Dahlstrom, U., Teng, K. T.-H., Bamadhaj, S., Ertl, G., Hassanein, M., Perrone, S. V., Ghandanfar, M., Schweizer, A., Obergfell, A., Filippatos, G., Collins, S. P., Lam, C. S.P., Dickstein, K. (2021) Global differences in burden and treatment of ischemic heart disease in acute heart failure: REPORT-HF. JACC: Heart Failure, 9, pp. 349-359. (doi: 10.1016/j.jchf.2020.12.015)

Mutambudzi, M., Niedzwiedz, C. L., Macdonald, E. B., Leyland, A. H., Mair, F. S., Anderson, J. J., Celis-Morales, C. A., Cleland, J. G., Forbes, J., Gill, J. M.R., Hastie, C. E., Ho, F. K., Jani, B. D., Mackay, D. F., Nicholl, B. I., O'Donnell, C. A., Sattar, N., Welsh, P., Pell, J. P., Katikireddi, S. V., Demou, E. (2021) Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants. Occupational and Environmental Medicine, 78, pp. 307-314. (doi: 10.1136/oemed-2020-106731)

Ferreira, J. P., Claggett, B. L., Liu, J., Desai, A. S., Pfeffer, M. A., Anand, I. S., Van Veldhuisen, D. J., Kober, L., Cleland, J. G.F., Rouleau, J. L., Packer, M., Zile, M. R., Shi, V. C., Lefkowitz, M. P., Shah, S. J., Vardeny, O., Zanannd, F., Solomon, S. D., McMurray, J. J.V. (2021) Serum potassium and outcomes in heart failure with preserved ejection fraction: a post-hoc analysis of the PARAGON-HF trial. European Journal of Heart Failure, 23, pp. 776-784. (doi: 10.1002/ejhf.2134)

Zhang, J., Pellicori, P., Schutte, R., Cleland, J.G. (2021) The association between blood groups and COVID-19 infection: a study from the UK Biobank. Journal of Internal Medicine, 289, pp. 747-748. (doi: 10.1111/joim.13226)

Pellicori, P., Platz, E., Dauw, J., ter Maaten, J. M., Martens, P., Pivetta, E., Cleland, J. G.F., McMurray, J. J.V., Mullens, W., Solomon, S. D., Zannad, F., Gargani, L., Girerd, N. (2021) Ultrasound imaging of congestion in heart failure – examinations beyond the heart. European Journal of Heart Failure, 23, pp. 703-712. (doi: 10.1002/ejhf.2032)

Coats, A. J. et al. (2021) The management of secondary mitral regurgitation in patients with heart failure: a joint position statement from the Heart Failure Association (HFA), European Association of Cardiovascular Imaging (EACVI), European Heart Rhythm Association (EHRA), and European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. European Heart Journal, 42, pp. 1254-1269. (doi: 10.1093/eurheartj/ehab086)

Mooney, L., Goodyear, C. S., Chandra, T., Kirschner, K., Copland, M., Petrie, M. C., Lang, N. N. (2021) Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure. Clinical Science, 135, pp. 991-1007. (doi: 10.1042/CS20200306)

Dewan, P., Docherty, K. F., Bengtsson, O., de Boer, R. A., Desai, A. S., Drozdz, J., Hawkins, N. M., Inzucchi, S. E., Kitakaze, M., Køber, L., Kosiborod, M. N., Langkilde, A. M., Lindholm, D., Martinez, F. A., Merkely, B., Petrie, M. C., Ponikowski, P., Sabatine, M. S., Schou, M., Sjöstrand, M., Solomon, S. D., Verma, S., Jhund, P. S., McMurray, J. J.V. (2021) Effects of dapagliflozin in heart failure with reduced ejection fraction, and chronic obstructive pulmonary disease: an analysis of DAPA-HF. European Journal of Heart Failure, 23, pp. 632-643. (doi: 10.1002/ejhf.2083)

Butt, J. H., Nicolau, J. C., Verma, S., Docherty, K. F., Petrie, M. C., Inzucchi, S. E., Schou, M., Kosiborod, M. N., Langkilde, A. M., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., Bengtsson, O., Jhund, P. S., McMurray, J., Køber, L. (2021) Efficacy and safety of dapagliflozin according to aetiology in heart failure with reduced ejection fraction: insights from the DAPA-HF trial. European Journal of Heart Failure, 23, pp. 601-613. (doi: 10.1002/ejhf.2124)

Mbakwem, A. C., Bauersachs, J., Viljoen, C., Hoevelmann, J., Meer, P., Petrie, M. C., Mebazaa, A., Goland, S., Karaye, K., Laroche, C., Sliwa, K. (2021) Electrocardiographic features and their echocardiographic correlates in peripartum cardiomyopathy: results from the ESC EORP PPCM registry. ESC Heart Failure, 8, pp. 879-889. (doi: 10.1002/ehf2.13172)

van Dorst, D. C.H., Dobbin, S. J.H., Neves, K. B., Herrmann, J., Herrmann, S. M., Versmissen, J., Mathijssen, R. H.J., Danser, A.H. J., Lang, N. N. (2021) Hypertension and prohypertensive antineoplastic therapies in cancer patients. Circulation Research, 128, pp. 1040-1061. (doi: 10.1161/CIRCRESAHA.121.318051)

Ferreira, J. P., Lam, C. S. P., Anker, S. D., Mehra, M. R., van Veldhuisen, D. J., Byra, W. M., La Police, D. A., Cleland, J. G.F., Greenberg, B., Zannad, F. (2021) Plasma D‐dimer concentrations predicting stroke risk and rivaroxaban benefit in patients with heart failure and sinus rhythm: an analysis from the COMMANDER‐HF trial. European Journal of Heart Failure, 23, pp. 648-656. (doi: 10.1002/ejhf.2003)

O’Sullivan, E. D., Lees, J. S., Howie, K. L., Pugh, D., Gillis, K. A., Traynor, J. P., Macintyre, I., Mark, P. B. (2021) Prolonged SARS-CoV-2 viral shedding in patients with chronic kidney disease. Nephrology, 26, pp. 328-332. (doi: 10.1111/nep.13844)

Ferreira, J. P. et al. (2021) Proteomic and mechanistic analysis of spironolactone in patients at risk for HF. JACC: Heart Failure, 9, pp. 268-277. (doi: 10.1016/j.jchf.2020.11.010)

Sliwa, K. et al. (2021) Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European Journal of Heart Failure, 23, pp. 527-540. (doi: 10.1002/ejhf.2133)

Uijl, A., Vaartjes, I., Denaxas, S., Hemingway, H., Shah, A. D., Cleland, J., Grobbee, D. E., Hoes, A. W., Asselbergs, F. W., Koudstaal, S. (2021) Temporal trends in heart failure medication prescription in a population-based cohort study. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-043290)

Mortensen, P., Gao, H., Smith, G., Simitev, R. D. (2021) Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling. Mathematical Medicine and Biology, 38, pp. 106-131. (doi: 10.1093/imammb/dqaa014)

Pellicori, P., Doolub, G., Wong, C. M., Lee, K. S., Mangion, K., Ahmad, M., Berry, C., Squire, I., Lambiase, P., Lyon, A. R., McConnachie, A., Taylor, R. S., Cleland, J. G.F. (2021) COVID-19 and its cardiovascular effects: a systematic review of prevalence studies. Cochrane Database of Systematic Reviews, 2021, (doi: 10.1002/14651858.CD013879)

Smart, N. A., Pearson, M. J., Taylor, R. S., Cleland, J. (2021) Exercise training for heart failure with preserved ejection fraction (ExTraMATCH III): protocol for an individual patient data meta-analysis. Journal of Clinical Exercise Physiology, 10, pp. 3-11. (doi: 10.31189/2165-7629-10.1.3)

Mordi, I. R., Ouwerkerk, W., Anker, S. D., Cleland, J. G., Dickstein, K., Metra, M., Ng, L. L., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Voors, A. A., Lang, C. C. (2021) Heart failure treatment up-titration and outcome and age: an analysis of BIOSTAT-CHF. European Journal of Heart Failure, 23, pp. 436-444. (doi: 10.1002/ejhf.1799)

Ferreira, J. P., Cleland, J. G.F., Lam, C. S.P., van Veldhuisen, D., Byra, W. M., La Police, D. A., Anker, S. D., Mehra, M. R., Leroy, C., Eschwege, V., Toussaint-Hacquard, M., Rossignol, P., Greenberg, B., Zannad, F. (2021) Impact of geographic region on the COMMANDER-HF Trial. JACC: Heart Failure, 9, pp. 201-211. (doi: 10.1016/j.jchf.2020.11.007)

Tomasoni, D., Petrie, M. C., Adamo, M., Metra, M. (2021) Renin-angiotensin-aldosterone inhibitors and COVID-19: nearing the end of a media-fuelled controversy. European Journal of Heart Failure, 23, pp. 486-488. (doi: 10.1002/ejhf.2098)

Cameron, A. C., Neves, K. B., White, J., Touyz, R. M., Lang, N. N. (2021) Reply: Cisplatin-associated aortic thrombosis: a review of cases reported to the FDA adverse event reporting system. JACC: CardioOncology, 3, pp. 166. (doi: 10.1016/j.jaccao.2021.01.005)

Hortigon-Vinagre, M.P., Zamora, V., Burton, F. L., Smith, G. L. (2021) The use of voltage sensitive dye di-4-ANEPPS and video-based contractility measurements to assess drug effects on excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes. Journal of Cardiovascular Pharmacology, 77, pp. 280-290. (doi: 10.1097/FJC.0000000000000937)

Pearson, R., Asher, J., Jackson, A., Mark, P. B., Shumeyko, V., Clancy, M. J. (2021) Viability assessment and utilization of declined donor kidneys with rhabdomyolysis using ex vivo normothermic perfusion without preimplantation biopsy. American Journal of Transplantation, 21, pp. 1317-1321. (doi: 10.1111/ajt.16329)

Lee, M. M.Y. et al. (2021) Invasive versus medically managed acute coronary syndromes with prior bypass (CABG-ACS): insights into the registry versus randomised trial populations. Open Heart, 8, (doi: 10.1136/openhrt-2020-001453)

Ehteshami-Afshar, S., Mooney, L., Dewan, P., Desai, A. S., Lang, N. N., Lefkowitz, M. P., Petrie, M. C., Rizkala, A. R., Rouleau, J. L., Solomon, S. D., Swedberg, K., Shi, V. C., Zile, M. R., Packer, M., McMurray, J. J.V., Jhund, P. S., Hawkins, N. M. (2021) Clinical characteristics and outcomes of patients with heart failure with reduced ejection fraction and chronic obstructive pulmonary disease: insights from PARADIGM-HF. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.120.019238)

Lee, M. M.Y. et al. (2021) Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 143, pp. 516-525. (doi: 10.1161/CIRCULATIONAHA.120.052186)

Petrie, M. C., Lee, M. M., Lang, N. N. (2021) EMPEROR-REDUCED reigns while EMPERIAL whimpers. European Heart Journal, 42, pp. 711-714. (doi: 10.1093/eurheartj/ehaa965)

Cleland, J. G.F. et al. (2021) The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart 'OMics' in AGEing (HOMAGE) randomized clinical trial. European Heart Journal, 42, pp. 684-696. (doi: 10.1093/eurheartj/ehaa758)

Rankin, A. J., Mark, P. B. (2021) Cardiac screening prior to renal transplantation – good intentions, rather than good evidence, dictate practice. Kidney International, 99, pp. 306-308. (doi: 10.1016/j.kint.2020.10.043)

Maznyczka, A. M., McCartney, P., Duklas, P., McEntegart, M., Oldroyd, K., Greenwood, J., Muir, D., Chowdhary, S., Gershlick, A. H., Eteiba, H., Cotton, J., Wragg, A., Curzen, N., Tait, R., Macfarlane, P., Welsh, P., Sattar, N., Petrie, M., Ford, I., Fox, K., McConnachie, A., Berry, C. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107, pp. 299-312. (doi: 10.1136/heartjnl-2020-317828)

Felker, G. M. et al. (2021) Effects of a novel nitroxyl donor in acute heart failure: the STAND-UP AHF Study. JACC: Heart Failure, 9, pp. 146-157. (doi: 10.1016/j.jchf.2020.10.012)

Halliday, B. P., Owen, R., Gregson, J., Vassiliou, V., Chen, X., Wage, R., Lota, A. S., Khalique, Z., Tayal, U., Hammersley, D. J., Jones, R. E., Baksi, A. J., Cowie, M. R., Cleland, J. G.F., Pennell, D. J., Prasad, S. K. (2021) Myocardial remodelling after withdrawing therapy for heart failure in patients with recovered dilated cardiomyopathy – insights from TRED‐HF. European Journal of Heart Failure, 23, pp. 293-301. (doi: 10.1002/ejhf.2063)

Docherty, K. F., Campbell, R. T., Brooksbank, K. J.M., Godeseth, R. L., Forsyth, P., McConnachie, A., Roditi, G., Stanley, B., Welsh, P., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2021) Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling. ESC Heart Failure, 8, pp. 129-138. (doi: 10.1002/ehf2.13137)

Andonovic, M., Shemilt, R., Sim, M., Traynor, J. P., Shaw, M., Mark, P. B., Puxty, K. A. (2021) Timing of renal replacement therapy for patients with acute kidney injury: a systematic review and meta-analysis. Journal of the Intensive Care Society, 22, pp. 67-77. (doi: 10.1177/1751143720901688)

Samuel, N. A., Cuthbert, J. J., Brown, O. I., Kazmi, S., Cleland, J. G.F., Rigby, A. S., Clark, A. L. (2021) Relation between thyroid function and mortality in patients with chronic heart failure. American Journal of Cardiology, 139, pp. 57-63. (doi: 10.1016/j.amjcard.2020.10.034)

Teerlink, J. R. et al. (2021) Cardiac myosin activation with omecamtiv mecarbil in systolic heart failure. New England Journal of Medicine, 384, pp. 105-116. (doi: 10.1056/NEJMoa2025797)

Bekfani, T., Fudim, M., Cleland, J. G.F., Jorbenadze, A., Haehling, S., Lorber, A., Rothman, A. M.‐K., Stein, K., Abraham, W. T., Sievert, H., Anker, S. D. (2021) A current and future outlook on upcoming technologies in the remote monitoring of patients with heart failure. European Journal of Heart Failure, 23, pp. 175-185. (doi: 10.1002/ejhf.2033)

Rutherford, E., Ireland, S., Mangion, K., Stewart, G. A., MacGregor, M., Roditi, G., Woodward, R., Gandy, S. J., Houston, J. G., Jardine, A., Rauchhaus, P., Witham, M. D., Mark, P. D., Struthers, A. D. (2021) A randomized, controlled trial of the effect of allopurinol on left ventricular mass index in hemodialysis patients. Kidney International Reports, 6, pp. 146-155. (doi: 10.1016/j.ekir.2020.10.025)

Dobbin, S. J.H., Petrie, M. C., Myles, R. C., Touyz, R. M., Lang, N. N. (2021) Cardiotoxic effects of angiogenesis inhibitors. Clinical Science, 135, pp. 71-100. (doi: 10.1042/CS20200305)

Lees, J. S., Mark, P. B. (2021) Cystatin C to predict renal disease and cardiovascular risk. Nephrology Dialysis Transplantation, 36, pp. 39-41. (doi: 10.1093/ndt/gfaa152)

Davison, B. A., Senger, S., Sama, I. E., Koch, G. G., Mebazaa, A., Dickstein, K., Samani, N. J., Metra, M., Anker, S. D., Cleland, J. G., Ng, L. L., Mordi, I. R., Zannad, F., Filippatos, G. S., Hillege, H. L., Ponikowski, P., Veldhuisen, D. J., Lang, C. C., Meer, P., Núñez, J., Bayés‐Genís, A., Edwards, C., Voors, A. A., Cotter, G. (2021) Is acute heart failure a distinctive disorder? An analysis from BIOSTAT‐CHF. European Journal of Heart Failure, 23, pp. 43-57. (doi: 10.1002/ejhf.2077)

McCallum, L., Brooksbank, K., McConnachie, A., Aman, A., Lip, S., Dawson, J., MacIntyre, I. M., MacDonald, T. M., Webb, D. J., Padmanabhan, S. (2021) Rationale and design of the genotype-blinded trial of torasemide for the treatment of hypertension (BHF UMOD) American Journal of Hypertension, 34, pp. 92-99. (doi: 10.1093/ajh/hpaa166)

Mark, P. B., Del Vecchio, L., Valdivielso, J. M., Malyszko, J. (2021) Same rhythm, different song - approaches to atrial fibrillation management by cardiologists and nephrologists. Clinical Kidney Journal, 14, pp. 9-13. (doi: 10.1093/ckj/sfaa146)

He, T., Melgarejo, J. D., Clark, A. L., Yu, Y.‐L., Thijs, L., Díez, J., López, B., González, A., Cleland, J. G., Schanstra, J. P., Vlahou, A., Latosinska, A., Mischak, H., Staessen, J. A., Zhang, Z.‐Y., Jankowski, V. (2021) Serum and urinary biomarkers of collagen type‐I turnover predict prognosis in patients with heart failure. Clinical and Translational Medicine, 11, (doi: 10.1002/ctm2.267)

Mortensen, P., Gao, H., Smith, G., Simitev, R. D. (2021) Addendum: Action potential propagation and block in a model of atrial tissue with myocyte-fibroblast coupling. Mathematical Medicine and Biology, 38, pp. 292-298. (doi: 10.1093/imammb/dqab005)

Dounousi, E., Tellis, C., Pavlakou, P., Duni, A., Liakopoulos, V., Mark, P. B., Papagianni, A., Tselepis, A. D. (2021) Association between PCSK9 levels and markers of inflammation, oxidative stress, and endothelial dysfunction in a population of nondialysis chronic kidney disease patients. Oxidative Medicine and Cellular Longevity, 2021, (doi: 10.1155/2021/6677012)

Da Silva Costa, A., Mortensen, P., Hortigon-Vinagre, M. P., van der Heyden, M. A. G., Burton, F. L., Gao, H., Simitev, R. D., Smith, G. L. (2021) Electrophysiology of hiPSC-cardiomyocytes co-cultured with HEK cells expressing the inward rectifier channel. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22126621)

Anderson, J. J., Welsh, P., Ho, F. K., Ferguson, L. D., Welsh, C. E., Pellicori, P., Cleland, J. G.F., Forbes, J., Iliodromiti, S., Boyle, J., Lindsay, R., Celis-Morales, C., Gray, S. R., Katikireddi, S. V., Gill, J. M. R., Pell, J. P., Sattar, N. (2021) Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening. BMJ Open Diabetes Research and Care, 9, (doi: 10.1136/bmjdrc-2021-002176)

McGettrick, M., MacLellan, A., McCaughey, P., Bagot, C., Brewis, M.J., Lang, N.N., Johnson, M.K., Church, A.C. (2021) Pulmonary thromboembolism in hospitalised patients with COVID-19: a retrospective national study of patients managed in critical care and ward environments in Scotland. BMJ Open, 11, (doi: 10.1136/bmjopen-2021-050281)

Shoaib, A., Van Spall, H. G.C., Wu, J., Cleland, J. G.F., McDonagh, T. A., Rashid, M., Mohamed, M. O., Ahmed, F. Z., Deanfield, J., de Belder, M., Gale, C. P., Mamas, M. A. (2021) Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic. European Heart Journal: Quality of Care and Clinical Outcomes, 7, pp. 378-387. (doi: 10.1093/ehjqcco/qcab040)

Pearson, R., Murray, E., Thomson, P. C., Mark, P. B., Clancy, M. J., Asher, J. (2021) The new UK national kidney allocation scheme with maximized “R4-D4” kidney transplants: better patient-to-graft longevity matching may be at the cost of more resources. Experimental and Clinical Transplantation, 19, pp. 1133-1141. (doi: 10.6002/ect.2021.0129)

2020

Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)

Lee, M. (2020) Studies of Empagliflozin and its Cardiovascular, Renal and Metabolic Effects in Patients With Diabetes Mellitus (or Prediabetes) and Heart Failure: a Randomized Controlled Trial (SUGAR-DM-HF) (doi: 10.1161/CIR.0000000000000940)

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Fudim, M., Dalgaard, F., Al-Khatib, S. M., J. Friedman, D., Lallinger, K., Abraham, W. T., Cleland, J. G.F., Curtis, A. B., Gold, M. R., Kutyifa, V., Linde, C., Schaber, D. E., Tang, A., Ali-Ahmed, F., Goldstein, S. A., Kaufman, B., Fortman, R., Davis, J. K., Inoue, L. Y.T., Sanders, G. D. (2020) Future research prioritization in cardiac resynchronization therapy. American Heart Journal, 223, pp. 48-58. (doi: 10.1016/j.ahj.2020.02.011)

Hawkins, N. M., Osmanska, J., Petrie, M. C. (2020) Implantable cardioverter-defibrillators and survival - the fine line between efficacy concerns and ageism. European Journal of Heart Failure, 22, pp. 868-870. (doi: 10.1002/ejhf.1803)

Cunningham, J. W., Ferreira, J. P., Deng, H., Anker, S. D., Byra, W. M., Cleland, J. G.F., Gheorghiade, M., Lam, C. S.P., La Police, D., Mehra, M. R., Neaton, J. D., Spiro, T. E., van Veldhuisen, D. J., Greenberg, B., Zannad, F. (2020) Natriuretic peptide-based inclusion criteria in a heart failure clinical trial: insights from COMMANDER HF. JACC: Heart Failure, 8, pp. 359-368. (doi: 10.1016/j.jchf.2019.12.009)

Hennigan, B., Berry, C., Collison, D., Corcoran, D., Eteiba, H., Good, R., McEntegart, M., Watkins, S., McClure, J., Mangion, K., Ford, T., Petrie, M. C., Hood, S., Rocchiccioli, P., Shaukat, A., Lindsay, M., Oldroyd, K. G. (2020) Percutaneous coronary intervention versus medical therapy in patients with angina and grey-zone fractional flow reserve values: a randomised clinical trial. Heart, 106, pp. 714-715. (doi: 10.1136/heartjnl-2019-316075)

Docherty, K. F., Ferreira, J. P., Sharma, A., Girerd, N., Gregson, J., Duarte, K., Petrie, M. C., Jhund, P. S., Dickstein, K., Pfeffer, M. A., Pitt, B., Rossignol, P., Zannad, F., McMurray, J. J.V. (2020) Predictors of sudden cardiac death in high-risk patients following a myocardial infarction. European Journal of Heart Failure, 22, pp. 848-855. (doi: 10.1002/ejhf.1694)

Quint, J. K., Rajagopalan, S., Cleland, J. G.F., Simon, D. I., Banerjee, A., Briere, J.-B., Bowrin, K., Cohen, A., Halcox, J., Zakeri, R., Bloom, C., Sundaram, V. (2020) Temporal trends in the incidence, treatment patterns, and outcomes of coronary artery disease and peripheral artery disease in the UK, 2006–2015. European Heart Journal, 41, pp. 1636-1649. (doi: 10.1093/eurheartj/ehz880)

Stoumpos, S., Mark, P., Kingsmore, D., Roditi, G., Radjenovic, A. (2020) Use of Ferumoxytol enhanced Magnetic Resonance Angiography for cardiovascular assessment in late-stage chronic kidney disease. (doi: 10.36399/gla.pubs.215112)

Petrie, M. C., et al. (2020) Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes. JAMA: Journal of the American Medical Association, 323, pp. 1353-1368. (doi: 10.1001/jama.2020.1906)

Kurkiewicz, A., Cooper, A., McIlwaine, E., Cumming, S. A., Adam, B., Krahe, R., Puymirat, J., Schoser, B., Timchenko, L., Ashizawa, T., Thornton, C. A., Rogers, S., McClure, J. D., Monckton, D. G. (2020) Towards development of a statistical framework to evaluate myotonic dystrophy type 1 mRNA biomarkers in the context of a clinical trial. PLoS ONE, 15, (doi: 10.1371/journal.pone.0231000)

Dietrichs, E. S., Tveita, T., Myles, R., Smith, G. (2020) A novel ECG-biomarker for cardiac arrest during hypothermia. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 28, (doi: 10.1186/s13049-020-00721-0)

Pandhi, P., Maaten, J. M., Emmens, J. E., Struck, J., Bergmann, A., Cleland, J. G., Givertz, M. M., Metra, M., O'Connor, C. M., Teerlink, J. R., Ponikowski, P., Cotter, G., Davison, B., Veldhuisen, D. J., Voors, A. A. (2020) Clinical value of pre‐discharge bio‐adrenomedullin as a marker of residual congestion and high risk of heart failure hospital readmission. European Journal of Heart Failure, 22, pp. 683-691. (doi: 10.1002/ejhf.1693)

Macdougall, I. C., Bhandari, S., White, C., Anker, S. D., Farrington, K., Kalra, P. A., Mark, P. B., McMurray, J. J.V., Reid, C., Robertson, M., Tomson, C. R.V., Wheeler, D. C., Winearls, C. G., Ford, I. (2020) Intravenous iron dosing and infection risk in patients on hemodialysis: a prespecified secondary analysis of the PIVOTAL trial. Journal of the American Society of Nephrology, 31, (doi: 10.1681/ASN.2019090972)

Rankin, A. J., Cannon, E., Gillis, K., Crosby, J., Mark, P. B., Geddes, C. C., Fox, J. G., Mackinnon, B., McQuarrie, E., Kipgen, D. (2020) Predicting outcome in acute interstitial nephritis: a case series examining the importance of histological parameters. Histopathology, 76, pp. 698-706. (doi: 10.1111/his.14031)

Simpson, J., Jhund, P. S., Lund, L. H., Padmanabhan, S., Clagget, B. L., Shen, L., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Kober, L., Paker, M., Rouleau, J. L., Mueller-Velten, G., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2020) Prognostic models derived in PARADIGM-HF and validated in ATMOSPHERE and the Swedish Heart Failure Registry to predict mortality and morbidity in chronic heart failure. JAMA Cardiology, 5, pp. 432-441. (doi: 10.1001/jamacardio.2019.5850)

Wehner, G. J., Jing, L., Haggerty, C. M., Suever, J. D., Leader, J. B., Hartzel, D. N., Kirchner, H. L., Manus, J. N.A., James, N., Ayar, Z., Gladding, P., Good, C. W., Cleland, J. G.F., Fornwalt, B. K. (2020) Routinely reported ejection fraction and mortality in clinical practice: where does the nadir of risk lie? European Heart Journal, 41, pp. 1249-1257. (doi: 10.1093/eurheartj/ehz550)

Cleland, J. G.F., Lyon, A. R., McDonagh, T., McMurray, J. J.V. (2020) The year in cardiology: heart failure. European Heart Journal, 41, pp. 1232-1248. (doi: 10.1093/eurheartj/ehz949)

Lee, M. M.Y., Petrie, M. C., McMurray, J. J.V., Sattar, N. (2020) How do SGLT2 (sodium-glucose cotransporter 2) inhibitors and GLP-1 (glucagon-like peptide-1) receptor agonists reduce cardiovascular outcomes? Arteriosclerosis, Thrombosis, and Vascular Biology, 40, pp. 506-522. (doi: 10.1161/atvbaha.119.311904)

Tromp, J., Bamadhaj, S., Cleland, J. G.F., Angermann, C. E., Dahlstrom, U., Ouwerkerk, W., Tay, W. T., Dickstein, K., Ertl, G., Hassanein, M., Hu, D., Perrone, S. V., Ghadanfar, M., Schweizer, A., Obergfell, A., Lam, C. S.P., Filippatos, G., Collins, S. P. (2020) Post-discharge prognosis of patients admitted to hospital for heart failure by world region, and national level of income and income disparity (REPORT-HF): a cohort study. Lancet Global Health, 8, pp. e411-e422. (doi: 10.1016/S2214-109X(20)30004-8)

Docherty, K. F., Shen, L., Castagno, D., Petrie, M. C., Abraham, W. T., Böhm, M., Desai, A. S., Dickstein, K., Køber, L. V., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Vazir, A., Zile, M. R., Jhund, P. S., McMurray, J. J.V. (2020) Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction. European Journal of Heart Failure, 22, pp. 528-538. (doi: 10.1002/ejhf.1682)

Santema, B. T., Chan, M. M.Y., Tromp, J., Dokter, M., van der Wal, H. H., Emmens, J. E., Takens, J., Samani, N. J., Ng, L. L., Lang, C. C., van der Meer, P., ter Maaten, J. M., Damman, K., Dickstein, K., Cleland, J. G., Zannad, F., Anker, S. D., Metra, M., van der Harst, P., de Boer, R. A., van Veldhuisen, D. J., Rienstra, M., Lam, C. S.P., Voors, A. A. (2020) The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure. Clinical Research in Cardiology, 109, pp. 331-338. (doi: 10.1007/s00392-019-01513-y)

Serenelli, M., Jackson, A., Dewan, P., Jhund, P. S., Petrie, M. C., Rossignol, P., Campo, G., Pitt, B., Zannad, F., Ferreira, J. P., McMurray, J. J.V. (2020) Mineralocorticoid receptor antagonists, blood pressure, and outcomes in heart failure with reduced ejection fraction. JACC: Heart Failure, 8, pp. 188-198. (doi: 10.1016/j.jchf.2019.09.011)

Cameron, A. C., Welsh, P., Neves, K. B., Newby, D., Touyz, R. M., Lang, N. (2020) Acute vascular effects of vascular endothelial growth factor inhibition in the forearm arterial circulation. Journal of Hypertension, 38, pp. 257-265. (doi: 10.1097/HJH.0000000000002230)

Rankin, A. J., Allwood-Spiers, S., Lee, M. M.Y., Zhu, L., Woodward, R., Kuehn, B., Radjenovic, A., Sattar, N., Roditi, G., Mark, P. B., Gillis, K. A. (2020) Comparing the interobserver reproducibility of different regions of interest on multi-parametric renal magnetic resonance imaging in healthy volunteers, patients with heart failure and renal transplant recipients. Magnetic Resonance Materials in Physics, Biology and Medicine, 33, pp. 103-112. (doi: 10.1007/s10334-019-00809-4)

Seferović, P. M. et al. (2020) European Society of Cardiology/Heart Failure Association position paper on the role and safety of new glucose‐lowering drugs in patients with heart failure. European Journal of Heart Failure, 22, pp. 196-213. (doi: 10.1002/ejhf.1673)

Bégué, C., Mörner, S., Brito, D., Hengstenberg, C., Cleland, J. G.F., Arbustini, E., Galve, E., Wichter, T., Richter, A., Golmard, J.-L., Bernard, M., Dubourg, O., Komajda, M., Charron, P., Isnard, R. (2020) Mid-regional proatrial natriuretic peptide for predicting prognosis in hypertrophic cardiomyopathy. Heart, 106, pp. 196-202. (doi: 10.1136/heartjnl-2019-314826)

Maznyczka, A. M. et al. (2020) One-year outcomes after low-dose intracoronary alteplase during primary percutaneous coronary intervention. The T-TIME randomized trial. Circulation: Cardiovascular Interventions, 13, (doi: 10.1161/CIRCINTERVENTIONS.119.008855)

Ford, T. J., Khan, A., Docherty, K. F., Jackson, A., Morrow, A., Sidik, N., Rocchiccioli, P., Good, R., Eteiba, H., Watkins, S., Shaukat, A., Lindsay, M., Robertson, K., Petrie, M., Berry, C., Oldroyd, K., McEntegart, M. (2020) Sex differences in procedural and clinical outcomes following rotational atherectomy. Catheterization and Cardiovascular Interventions, 95, pp. 232-241. (doi: 10.1002/ccd.28373)

Hockings, P., Laustsen, C., Joles, J., Mark, P., Sourbron, S. (2020) Special issue on magnetic resonance imaging biomarkers of renal disease. Magnetic Resonance Materials in Physics, Biology and Medicine, 33, pp. 1-2. (doi: 10.1007/s10334-019-00822-7)

Welsh, C., Welsh, P., Celis Morales, C. A., Mark, P., Mackay, D., Ghouri, N., Ho, F., Ferguson, L. D., Brown, R., Lewsey, J., Cleland, J. G., Gray, S. R., Lyall, D. M., Anderson, J., Jhund, P. S., Pell, J., McGuire, D. K., Gill, J. M.R., Sattar, N. (2020) Glycated hemoglobin, prediabetes and the links to cardiovascular disease: data from UK Biobank. Diabetes Care, 43, pp. 440-445. (doi: 10.2337/dc19-1683)

Kosiborod, M. N., Jhund, P., Docherty, K. F., Diez, M., Petrie, M. C., Verma, S., Nicolau, J. C., Merkely, B., Kitakaze, M., DeMets, D. L., Inzucchi, S. E., Køeber, L., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Bengtsson, O., Lindholm, D., Niklasson, A., Sjöstrand, M., Langkilde, A. M., McMurray, J. J.V. (2020) Effects of dapagliflozin on symptoms, function and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial. Circulation, 141, pp. 90-99. (doi: 10.1161/CIRCULATIONAHA.119.044138)

Martinez, F. A., Serenelli, M., Nicolau, J. C., Petrie, M. C., Chiang, C.-E., Tereshchenko, S., Solomon, S. D., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Ponikowski, P., Sabatine, M. S., DeMets, D. L., Dutkiewicz-Piasecka, M., Bengtsson, O., Sjöstrand, M., Langkilde, A. M., Jhund, P., McMurray, J. J.V. (2020) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to age: insights from DAPA-HF. Circulation, 141, pp. 100-111. (doi: 10.1161/CIRCULATIONAHA.119.044133)

Filippatos, G., Angermann, C. E., Cleland, J. G.F., Lam, C. S.P., Dahlström, U., Dickstein, K., Ertl, G., Hassanein, M., Hart, K. W., Lindsell, C. J., Perrone, S. V., Guerin, T., Ghadanfar, M., Schweizer, A., Obergfell, A., Collins, S. P. (2020) Global differences in characteristics, precipitants, and initial management of patients presenting with acute heart failure. JAMA Cardiology, 5, pp. 401-410. (doi: 10.1001/jamacardio.2019.5108)

Ferreira, J. P., Ouwerkerk, W., Tromp, J., Ng, L., Dickstein, K., Anker, S., Filippatos, G., Cleland, J. G., Metra, M., van Veldhuisen, D. J., Voors, A. A., Zannad, F. (2020) Cardiovascular and non‐cardiovascular death distinction: the utility of troponin beyond N‐terminal pro‐B‐type natriuretic peptide. Findings from the BIOSTAT‐CHF study. European Journal of Heart Failure, 22, pp. 81-89. (doi: 10.1002/ejhf.1654)

Pellicori, P., Cleland, J. G.F., Clark, A. L. (2020) Chronic obstructive pulmonary disease and heart failure: a breathless conspiracy. Heart Failure Clinics, 16, pp. 33-44. (doi: 10.1016/j.hfc.2019.08.003)

Nikolaidou, T., Samuel, N. A., Marincowitz, C., Fox, D. J., Cleland, J. G.F., Clark, A. L. (2020) Electrocardiographic characteristics in patients with heart failure and normal ejection fraction: a systematic review and meta‐analysis. Annals of Noninvasive Electrocardiology, 25, (doi: 10.1111/anec.12710)

Li, Z. et al. (2020) General principles for the validation of proarrhythmia risk prediction models: an extension of the CiPA In Silico Strategy. Clinical Pharmacology and Therapeutics, 107, pp. 102-111. (doi: 10.1002/cpt.1647)

Kobayashi, M., Voors, A. A., Girerd, N., Billotte, M., Anker, S. D., Cleland, J. G., Lang, C. C., Ng, L. L., van Veldhuisen, D. J., Dickstein, K., Metra, M., Duarte, K., Rossignol, P., Zannad, F., Ferreira, J. P. (2020) Heart failure etiologies and clinical factors precipitating for worsening heart failure: Findings from BIOSTAT-CHF. European Journal of Internal Medicine, 71, pp. 62-69. (doi: 10.1016/j.ejim.2019.10.017)

Pellicori, P., Zhang, J., Cuthbert, J., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L., Cleland, J. G.F. (2020) High sensitivity C-reactive protein in chronic heart failure: patient characteristics, phenotypes, and mode of death. Cardiovascular Research, 116, pp. 91-100. (doi: 10.1093/cvr/cvz198)

Pellicori, P., Khan, M. J. I., Graham, F. J., Cleland, J. G.F. (2020) New perspectives and future directions in the treatment of heart failure. Heart Failure Reviews, 25, pp. 147-159. (doi: 10.1007/s10741-019-09829-7)

Cao, T. H., Jones, D. J.L., Voors, A. A., Quinn, P. A., Sandhu, J. K., Chan, D. C.S., Parry, H. M., Mohan, M., Mordi, I. R., Sama, I. E., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Lang, C. C., Ng, L. L. (2020) Plasma proteomic approach in patients with heart failure: insights into pathogenesis of disease progression and potential novel treatment targets. European Journal of Heart Failure, 22, pp. 70-80. (doi: 10.1002/ejhf.1608)

McArthur, L., Riddell, A., Chilton, L., Smith, G. L., Nicklin, S. A. (2020) Regulation of connexin 43 by interleukin 1β in adult rat cardiac fibroblasts and effects in an adult rat cardiac myocyte: fibroblast co-culture model. Heliyon, 6, (doi: 10.1016/j.heliyon.2019.e03031)

Mark, P. B., Papworth, R., Ramparsad, N., Tomlinson, L. A., Sahwney, S., Black, C., McConnachie, A., McCowan, C. (2020) Risk factors associated with biochemically detected and hospitalised acute kidney injury in patients prescribed renin angiotensin system inhibitors. British Journal of Clinical Pharmacology, 86, pp. 121-131. (doi: 10.1111/bcp.14141)

de Korte, T., Katili, P. A., Mohd Yusof, N. A.N., van Meer, B. J., Saleem, U., Burton, F. L., Smith, G. L., Clements, P., Mummery, C. L., Eschenhagen, T., Hansen, A., Denning, C. (2020) Unlocking personalized biomedicine and drug discovery with human induced pluripotent stem cell–derived cardiomyocytes: fit for purpose or forever elusive? Annual Review of Pharmacology and Toxicology, 60, pp. 529-551. (doi: 10.1146/annurev-pharmtox-010919-023309)

Anker, M. S., Hülsmann, M., Cleland, J. G. (2020) What do patients with heart failure die from? A single assassin or a conspiracy? European Journal of Heart Failure, 22, pp. 26-28. (doi: 10.1002/ejhf.1689)

Heggie, R., Wu, O., Boyd, K., Lee, M. M.Y., Petrie, M. C., McEntegart, M., Berry, C. (2020) Does routine invasive management benefit patients presenting with an acute coronary syndrome and a history of bypass surgery? The use of clinical outcomes compared with cost-effectiveness outcomes.

Israr, M. Z. et al. (2020) Implications of serial measurements of natriuretic peptides in heart failure: insights from BIOSTAT‐CHF. European Journal of Heart Failure, 22, pp. 1486-1490. (doi: 10.1002/ejhf.1951)

2019

Gould, G., Bowman, P., Smith, G. (2019) Cardiac SNARE expression in health and disease. Frontiers in Endocrinology, 10, (doi: 10.3389/fendo.2019.00881)

Kotecha, D., Gill, S. K., Flather, M. D., Holmes, J., Packer, M., Rosano, G., Böhm, M., McMurray, J. J.V., Wikstrand, J., Anker, S. D., van Veldhuisen, D. J., Manzano, L., von Lueder, T. G., Rigby, A. S., Andersson, B., Kjekshus, J., Wedel, H., Ruschitzka, F., Cleland, J. G.F., Damman, K., Redon, J., Coats, A. J.S. (2019) Impact of renal impairment on beta-blocker efficacy in patients with heart failure. Journal of the American College of Cardiology, 74, pp. 2893-2904. (doi: 10.1016/j.jacc.2019.09.059)

Dewan, P., Rorth, R., Raparelli, V., Campbell, R. T., Shen, L., Jhund, P. S., Petrie, M. C., Anand, I. S., Carson, P. E., Desai, A. S., Granger, C. B., Køber, L., Komajda, M., McKelvie, R. S., O'Meara, E., Pfeffer, M. A., Pitt, B., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Sex-related differences in heart failure with preserved ejection fraction. Circulation: Heart Failure, 12, (doi: 10.1161/CIRCHEARTFAILURE.119.006539)

Mace-Brickman, T., Eddeen, A. B., Carrero, J.-J., Mark, P. B., Molnar, A. O., Lam, N. N., Zimmerman, D., Harel, Z., Sood, M. M. (2019) The risk of stroke and stroke type in patients with atrial fibrillation and chronic kidney disease. Canadian Journal of Kidney Health and Disease, 6, pp. 1-9. (doi: 10.1177/2054358119892372)

Kammer, M., Heinzel, A., Willency, J., Duffin, K., Mayer, G., Simons, K., Gerl, M., Klose, C., Heinze, G., Reindl-Schwaighofer, R., Hu, K., Perco, P., Eder, S., Rosivall, L., Mark, P., Ju, W., Kretzler, M., McCarthy, M., Heerspink, H. J., Wiecek, A., Gomez, M., Oberbauer, R. (2019) Integrative analysis of prognostic biomarkers derived from multiomics panels for the discrimination of chronic kidney disease trajectories in people with type 2 diabetes. Kidney International, 96, pp. 1381-1388. (doi: 10.1016/j.kint.2019.07.025)

Williams, E. H. et al. (2019) Multicentre validation of the CamGFR model for estimated glomerular filtration rate. JNCI Cancer Spectrum, 3, (doi: 10.1093/jncics/pkz068)

Johnson, M. J., Cockayne, S., Currow, D. C., Bell, K., Hicks, K., Fairhurst, C., Gabe, R., Torgerson, D., Jefferson, L., Oxberry, S., Ghosh, J., Hogg, K. J., Murphy, J., Allgar, V., Cleland, J. G.F., Clark, A. L. (2019) Oral modified release morphine for breathlessness in chronic heart failure: a randomised placebo-controlled trial. ESC Heart Failure, 6, pp. 1149-1160. (doi: 10.1002/ehf2.12498)

Cameron, A. C., Lang, N. N., Dominiczak, A. F., Jennings, G. L.R., Batlle, D., Bursztyn, M., Chugh, A. R., Floras, J. S., Taler, S. J., Touyz, R. M., Delles, C. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74, pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343)

Sharma, V. et al. (2019) Report from the Annual Conference of the British Society of Echocardiography, November 2017, Edinburgh International Conference Centre, Edinburgh. Echo Research and Practice, 6, pp. M1-M2. (doi: 10.1530/ERP-19-0056)

Mehra, M. R., Vaduganathan, M., Fu, M., Ferreira, J. P., Anker, S. A., Cleland, J. G.F., Lam, C. S.P., van Veldhuisen, D. J., Byra, W. M., Spiro, T., Deng, H., Zannad, F., Greenberg, B. (2019) A comprehensive analysis of the effects of rivaroxaban on stroke or transient ischaemic attack in patients with heart failure, coronary artery disease, and sinus rhythm: the COMMANDER HF trial. European Heart Journal, 40, pp. 3593-3602. (doi: 10.1093/eurheartj/ehz427)

McMurray, J. J.V. et al. (2019) Dapagliflozin in patients with heart failure and reduced ejection fraction. New England Journal of Medicine, 381, pp. 1995-2008. (doi: 10.1056/NEJMoa1911303)

Sillars, A., Celis-Morales, C. A., Ho, F., Petermann, F., Welsh, P., Iliodromiti, S., Ferguson, L. D., Lyall, D. M., Anderson, J., Mackay, D., Pellicori, P., Cleland, J., Pell, J. P., Gill, J. M.R., Gray, S. R., Sattar, N. (2019) Association of fitness and grip-strength with heart failure: findings from the UK Biobank population-based study. Mayo Clinic Proceedings, 94, pp. 2230-2240. (doi: 10.1016/j.mayocp.2019.04.041)

Lees, J. S., Welsh, C. E., Celis-Morales, C. A., Mackay, D., Lewsey, J., Gray, S. R., Lyall, D. M., Cleland, J. G., Gill, J. M.R., Jhund, P. S., Pell, J., Sattar, N., Welsh, P., Mark, P. B. (2019) Glomerular filtration rate by differing measures, albuminuria and prediction of cardiovascular disease, mortality and end-stage kidney disease. Nature Medicine, 25, pp. 1753-1760. (doi: 10.1038/s41591-019-0627-8)

Beusekamp, J. C., Tromp, J., Cleland, J. G.F., Givertz, M. M., Metra, M., O’Connor, C. M., Teerlink, J. R., Ponikowski, P., Ouwerkerk, W., van Veldhuisen, D. J., Voors, A. A., van der Meer, P. (2019) Hyperkalemia and treatment with RAAS inhibitors during acute heart failure hospitalizations and their association with mortality. JACC: Heart Failure, 7, pp. 970-979. (doi: 10.1016/j.jchf.2019.07.010)

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Shen, L., Jhund, P. S., Docherty, K. F., Petrie, M. C., Anand, I. S., Carson, P. E., Desai, A. S., Granger, C. B., Komajda, M., McKelvie, R. S., Pfeffer, M. A., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Prior pacemaker implantation and clinical outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 7, pp. 418-427. (doi: 10.1016/j.jchf.2018.12.006)

Ferreira, J. P. et al. (2019) Proteomic bioprofiles and mechanistic pathways of progression to heart failure: the HOMAGE study. Circulation, 12, (doi: 10.1161/CIRCHEARTFAILURE.118.005897)

Anderson, S. G., Shoaib, A., Myint, P. K., Cleland, J. G., Hardman, S. M., McDonagh, T. A., Dargie, H., Keavney, B., Garratt, C. J., Mamas, M. A. (2019) Does rhythm matter in Acute Heart Failure? An insight from the British Society for Heart Failure National Audit. Clinical Research in Cardiology, (doi: 10.1007/s00392-019-01463-5)

Ghouri, I. A., Kelly, A., Salerno, S., Garten, K., Stølen, T., Kemi, O.-J., Smith, G. L. (2019) Corrigendum: Characterization of electrical activity in post-myocardial infarction scar tissue in rat hearts using multiphoton microscopy. Frontiers in Physiology, 10, (doi: 10.3389/fphys.2019.00364)

Wolsk, E., Kaye, D., Komtebedde, J., Shah, S. J., Borlaug, B. A., Burkhoff, D., Kitzman, D. W., Lam, C. S.P., van Veldhuisen, D. J., Ponikowski, P., Petrie, M. C., Hassager, C., Møller, J. E., Gustafsson, F. (2019) Central and peripheral determinants of exercise capacity in heart failure patients with preserved ejection fraction. JACC: Heart Failure, 7, pp. 321-332. (doi: 10.1016/j.jchf.2019.01.006)

Maznyczka, A. M., Carrick, D., Carberry, J., Mangion, K., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Ford, I., Welsh, P., Sattar, N., Oldroyd, K. G., Berry, C. (2019) Sex-based associations with microvascular injury and outcomes after ST-segment elevation myocardial infarction. Open Heart, 6, (doi: 10.1136/openhrt-2018-000979)

Pettit, S. J., Petrie, M. C. (2019) Transplantation of hearts donated after circulatory-determined death: a song of fire and ice. Circulation: Heart Failure, 12, (doi: 10.1161/CIRCHEARTFAILURE.119.005991)

Sokoreli, I., Cleland, J.G., Pauws, S.C., Steyerberg, E.W., de Vries, J.J.G., Riistama, J.M., Dobbs, K., Bulemfu, J., Clark, A.L. (2019) Added value of frailty and social support in predicting risk of 30-day unplanned re-admission or death for patients with heart failure: an analysis from OPERA-HF. International Journal of Cardiology, 278, pp. 167-172. (doi: 10.1016/j.ijcard.2018.12.030)

Dietrichs, E. S., Tveita, T., Smith, G. (2019) Hypothermia and cardiac electrophysiology: a systematic review of clinical and experimental data. Cardiovascular Research, 115, pp. 501-509. (doi: 10.1093/cvr/cvy305)

Januzzi, J., Ferreira, J. P., Böhm, M., Kaul, S., Wanner, C., Brueckmann, M., Petrie, M., Ofstad, A.-P., Zeller, C., George, J., Fitchett, D., Zannad, F. (2019) Empagliflozin reduces the risk of a broad spectrum of heart failure outcomes regardless of heart failure status at baseline. European Journal of Heart Failure, 21, pp. 386-388. (doi: 10.1002/ejhf.1419)

Stapleton, C. P., Birdwell, K. A., McKnight, A. J., Maxwell, A. P., Mark, P. B., Sanders, M. L., Chapman, F. A., van Setten, J., Phelan, P. J., Kennedy, C., Jardine, A., Traynor, J. P., Keating, B., Conlon, P. J., Cavalleri, G. L. (2019) Polygenic risk score as a determinant of risk of non-melanoma skin cancer in a European-descent renal transplant cohort. American Journal of Transplantation, 19, pp. 801-810. (doi: 10.1111/ajt.15057)

Mangion, K., Carrick, D., Clerfond, G., Rush, C., McComb, C., Oldroyd, K. G., Petrie, M. C., Eteiba, H., Lindsay, M., McEntegart, M., Hood, S., Watkins, S., Davie, A., Auger, D. A., Zhong, X., Epstein, F. H., Haig, C. E., Berry, C. (2019) Predictors of segmental myocardial functional recovery in patients after an acute ST-elevation myocardial infarction. European Journal of Radiology, 112, pp. 121-129. (doi: 10.1016/j.ejrad.2019.01.010)

Loader, J., Chan, Y.-K., A Hawley, J., Moholdt, T., McDonald, C. F., Jhund, P., Petrie, M. C., McMurray, J. J., Scuffham, P. A., Ramchand, J., Burrell, L. M., Stewart, S. (2019) Prevalence and profile of "seasonal frequent flyers" with chronic heart disease: analysis of 1598 patients and 4588 patient-years follow-up. International Journal of Cardiology, 279, pp. 126-132. (doi: 10.1016/j.ijcard.2018.12.060)

de Boer, R. A. et al. (2019) Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology. European Journal of Heart Failure, 21, pp. 272-285. (doi: 10.1002/ejhf.1406)

Mamet, H., Petrie, M. C., Rocchiccioli, P. (2019) Type 1 diabetes mellitus and coronary revascularization. Cardiovascular Endocrinology and Metabolism, 8, pp. 35-38. (doi: 10.1097/XCE.0000000000000166)

Cleland, J. G.F., van Veldhuisen, D. J., Ponikowski, P. (2019) The year in cardiology 2018: heart failure. European Heart Journal, 40, pp. 651-661. (doi: 10.1093/eurheartj/ehz010)

Brooksbank, K., O'Donnell, J., Corbett, V., Shield, S., Ainsworth, R., Shearer, R., Montgomery, S., Gallagher, A., Duncan, H., Hamilton, L., Laszlo, V., Noone, R., Baxendale, A., Blane, D., Logue, J. (2019) Discussing weight management with type 2 diabetes patients in primary care using the Small Talk Big Difference intervention: Protocol for a randomised controlled trial. JMIR Research Protocols, 8, (doi: 10.2196/12162)

Avtaar Singh, S. S., Das De, S., Nappi, F., Al-Adhami, A., Hegazy, Y., Dalzell, J., Doshi, H., Sinclair, A., Curry, P., Petrie, M., Berry, C., Al-Attar, N. (2019) Mechanical circulatory support for refractory cardiogenic shock post-acute myocardial infarction-a decade of lessons. Journal of Thoracic Disease, 11, pp. 542-548. (doi: 10.21037/jtd.2019.01.21)

Zhang, J., Begley, A., Jackson, R., Harrison, M., Pellicori, P., Clark, A. L., Cleland, J. G.F. (2019) Body mass index and all-cause mortality in heart failure patients with normal and reduced ventricular ejection fraction: a dose–response meta-analysis. Clinical Research in Cardiology, 108, pp. 119-132. (doi: 10.1007/s00392-018-1302-7)

Mangion, K., Carrick, D., Carberry, J., Mahrous, A., McComb, C., Oldroyd, K. G., Eteiba, H., Lindsay, M., McEntegart, M., Hood, S., Petrie, M. C., Watkins, S., Davie, A., Zhong, X., Epstein, F. H., Haig, C. E., Berry, C. (2019) Circumferential strain predicts major adverse cardiovascular events following an acute ST-segment-elevation myocardial infarction. Radiology, 290, pp. 329-337. (doi: 10.1148/radiol.2018181253)

Ferreira, J. P., Metra, M., Anker, S. D., Dickstein, K., Lang, C. C., Ng, L., Samani, N. J., Cleland, J. G., van Veldhuisen, D. J., Voors, A. A., Zannad, F. (2019) Clinical correlates and outcome associated with changes in 6-minute walking distance in patients with heart failure: findings from the BIOSTAT-CHF study. European Journal of Heart Failure, 21, pp. 218-226. (doi: 10.1002/ejhf.1380)

Kaye, D. M., Petrie, M. C., McKenzie, S., Hasenfuβ, G., Malek, F., Post, M., Doughty, R. N., Trochu, J.-N., Gustafsson, F., Lang, I., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Hausleiter, J., Raake, P., Jondeau, G., Bergmann, M. W., Spelman, T., Aytug, H., Ponikowski, P., Hayward, C. (2019) Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction. ESC Heart Failure, 6, pp. 62-69. (doi: 10.1002/ehf2.12350)

Gillis, K. A., Lees, J. S., Ralston, M. R., Glen, J. A., Stevenson, K. S., McManus, S. K., Geddes, C. C., Clancy, M., Traynor, J. P., Mark, P. B. (2019) Interaction between socioeconomic deprivation and likelihood of pre‐emptive transplantation: influence of competing risks and referral characteristics – a retrospective study. Transplant International, 32, pp. 153-162. (doi: 10.1111/tri.13336)

Bekfani, T., Pellicori, P., Morris, D., Ebner, N., Valentova, M., Sandek, A., Doehner, W., Cleland, J. G., Lainscak, M., Schulze, P. C., Anker, S. D., von Haehling, S. (2019) Iron deficiency in patients with heart failure with preserved ejection fraction and its association with reduced exercise capacity, muscle strength and quality of life. Clinical Research in Cardiology, 108, pp. 203-211. (doi: 10.1007/s00392-018-1344-x)

Ferreira, J. P., Rossignol, P., Pizard, A., Machu, J.-L., Collier, T., Girerd, N., Huby, A.-C., Gonzalez, A., Diez, J., López, B., Sattar, N., Cleland, J. G., Sever, P. S., Zannad, F. (2019) Potential spironolactone effects on collagen metabolism biomarkers in patients with uncontrolled blood pressure. Heart, 105, pp. 307-314. (doi: 10.1136/heartjnl-2018-313182)

Ambrosy, A. P., Stevens, S. R., Al-Khalidi, H. R., Rouleau, J. L., Bouabdallaoui, N., Carson, P. E., Adlbrecht, C., Cleland, J. G.F., Dabrowski, R., Golba, K. S., Pina, I. L., Sueta, C. A., Roy, A., Sopko, G., Bonow, R. O., Velazquez, E. J. (2019) Burden of medical co-morbidities and benefit from surgical revascularization in patients with ischaemic cardiomyopathy. European Journal of Heart Failure, 21, pp. 373-381. (doi: 10.1002/ejhf.1404)

Lee, M. M.Y., Campbell, R. T., Kelly, R., Petrie, M. C., Sonecki, P. (2019) Does “Scar” at Rest Echocardiography Predict Lack of Contractility Reserve at Dobutamine Stress Echocardiography. (doi: 10.1093/ehjci/jey266)

Keeble, T. R., Karamasis, G. V., Rothman, M. T., Ricksten, S.-E., Ferrari, M., Hullin, R., Scherstén, F., Reitan, O., Kirking, S. T., Cleland, J. G.F., Smith, E. J. (2019) Percutaneous haemodynamic and renal support in patients presenting with decompensated heart failure: A multi-centre efficacy study using the Reitan Catheter Pump (RCP) International Journal of Cardiology, 275, pp. 53-58. (doi: 10.1016/j.ijcard.2018.09.085)

Dewan, P., Rørth, R., Jhund, P. S., Shen, L., Raparelli, V., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Køber, L., Mogensen, U. M., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Differential impact of heart failure with reduced ejection fraction on men and women. Journal of the American College of Cardiology, 73, pp. 29-40. (doi: 10.1016/j.jacc.2018.09.081)

Halliday, B. P. et al. (2019) Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial. Lancet, 393, pp. 61-73. (doi: 10.1016/S0140-6736(18)32484-X)

McCartney, P. J. et al. (2019) Effect of low-dose intracoronary alteplase during primary percutaneous coronary intervention on microvascular obstruction in patients with acute myocardial infarction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321, pp. 56-68. (doi: 10.1001/jama.2018.19802)

Kerr, D. M.I., Brooksbank, K. J.M., Taylor, R. G., Pinel, K., Rios, F. J., Touyz, R. M., Delles, C. (2019) Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: a cross-over study. Journal of Hypertension, 37, pp. 154-166. (doi: 10.1097/HJH.0000000000001890)

Lee, M. M. Y., McMurray, J. J.V., Lorenzo-Almorós, A., Kristensen, S. L., Sattar, N., Jhund, P. S., Petrie, M. C. (2019) Diabetic cardiomyopathy. Heart, 105, pp. 337-345. (doi: 10.1136/heartjnl-2016-310342)

Eder, S., Leierer, J., Kerschbaum, J., Rosivall, L., Wiecek, A., de Zeeuw, D., Mark, P. B., Heinze, G., Rossing, P., Heerspink, H. L., Mayer, G. (2019) Guidelines and clinical practice at the primary level of healthcare in patients with type 2 diabetes mellitus with and without kidney disease in five European countries. Diabetes and Vascular Disease Research, 16, pp. 47-56. (doi: 10.1177/1479164118795559)

Findlay, M. D., Dawson, J., Dickie, D. A., Forbes, K. P., McGlynn, D., Quinn, T., Mark, P. B. (2019) Investigating the relationship between cerebral blood flow and cognitive function in hemodialysis patients. Journal of the American Society of Nephrology, 30, pp. 147-158. (doi: 10.1681/ASN.2018050462)

Lees, J.S., Findlay, M.D., Mark, P.B., Geddes, C.C. (2019) The impact of coronary angiography on renal transplant function. QJM: An International Journal of Medicine, 112, pp. 23-27. (doi: 10.1093/qjmed/hcy216)

Cameron, A. C., Rossitto, G., Lang, N. N., Touyz, R. M. (2019) Antihypertensive drugs and vascular health. Springer

Haile, D. W., Durussel, J., Mekonen, W., Ongaro, N., Anjila, E., Mooses, M., Daskalaki, E., Mooses, K., McClure, J. D., Sutehall, S., Pitsiladis, Y. P. (2019) Effects of EPO on blood parameters and running performance in Kenyan athletes. Medicine and Science in Sports and Exercise, 51, pp. 299-307. (doi: 10.1249/MSS.0000000000001777)

Pfeiffer-Kaushik, E. R., Smith, G. L., Cai, B., Dempsey, G. T., Hortigon-Vinagre, M. P., Zamora, V., Feng, S., Ingermanson, R., Zhu, R., Hariharan, V., Nguyen, C., Pierson, J., Gintant, G. A., Tung, L. (2019) Electrophysiological characterization of drug response in hSC-derived cardiomyocytes using voltage-sensitive optical platforms. Journal of Pharmacological and Toxicological Methods, 99, (doi: 10.1016/j.vascn.2019.106612)

Rush, C. J., Petrie, M. C. (2019) Heart failure with preserved ejection fraction. Springer

Skopalik, S., Hall Barrientos, P., Matthews, J., Radjenovic, A., Mark, P., Roditi, G., Paul, M.C. (2019) Image-based Computational Fluid Dynamics for Estimating Pressure Drop and FFR Across Iliac Artery Stenosis: a Comprison with In-vivo Measurements.

Mark, P. B., Denby, L. (2019) Renal disease. Springer

Findlay, M., Macisaac, R., MacLeod, M. J., Metcalfe, W., Sood, M. M., Traynor, J. P., Dawson, J., Mark, P. B. (2019) The association of atrial fibrillation and ischaemic stroke in patients on haemodialysis: a competing risk analysis. Canadian Journal of Kidney Health and Disease, 6, pp. 1-13. (doi: 10.1177/2054358119878719)

Cameron, A. C., Touyz, R. M., Lang, N. N. (2019) Vascular biology of cancer chemotherapeutic drugs. Springer

Nather, K., Loughrey, C. M., Nicklin, S. A. (2019) Vasoactive peptides: renin-angiotensin-aldosterone system. Springer

2018

Lemme, M., Ulmer, B. M., Lemoine, M. D., Zech, A. T.L., Flenner, F., Ravens, U., Reichenspurner, H., Rol-Garcia, M., Smith, G., Hansen, A., Christ, T., Eschenhagen, T. (2018) Atrial-like engineered heart tissue: an in vitro model of the human atrium. Stem Cell Reports, 11, pp. 1378-1390. (doi: 10.1016/j.stemcr.2018.10.008)

Ferro, C. J., Mark, P. B., Kanbay, M., Sarafidis, P., Heine, G. H., Rossignol, P., Massy, Z. A., Mallamaci, F., Valdivielso, J. M., Malyszko, J., Verhaar, M. C., Ekart, R., Vanholder, R., London, G., Ortiz, A., Zoccali, C. (2018) Lipid management in patients with chronic kidney disease. Nature Reviews Nephrology, 14, pp. 727-749. (doi: 10.1038/s41581-018-0072-9)

Rossitto, G., Touyz, R. M., Petrie, M. C., Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132, pp. 2609-2613. (doi: 10.1042/CS20180575)

Tromp, J., Ouwerkerk, W., Demissei, B.G., Anker, S.D., Cleland, J.G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H.L., Lang, C.C., Metra, M., Ng, L.L., Ponikowski, P., Samani, N.J., van Veldhuisen, D.J., Zannad, F., Zwinderman, A.H., Voors, A.A., van der Meer, P. (2018) Novel endotypes in heart failure: effects on guideline-directed medical therapy. European Heart Journal, 39, pp. 4269-4276. (doi: 10.1093/eurheartj/ehy712)

Shiraishi, Y., Nagai, T., Kohsaka, S., Goda, A., Nagatomo, Y., Mizuno, A., Kohno, T., Rigby, A., Fukuda, K., Yoshikawa, T., Clark, A. L., Cleland, J. G.F. (2018) Outcome of hospitalised heart failure in Japan and the United Kingdom stratified by plasma N-terminal pro-B-type natriuretic peptide. Clinical Research in Cardiology, 107, pp. 1103-1110. (doi: 10.1007/s00392-018-1283-6)

Abuosa, A. M., Elshiekh, A. H., Qureshi, K., Abrar, M. B., Kholeif, M. A., Kinsara, A. J., Andejani, A., Ahmed, A. H., Cleland, J. G.F. (2018) Prophylactic use of carvedilol to prevent ventricular dysfunction in patients with cancer treated with doxorubicin. Indian Heart Journal, 70, pp. S96-S100. (doi: 10.1016/j.ihj.2018.06.011)

Campbell, R. T., Petrie, M. C., McMurray, J. J.V. (2018) Redefining heart failure phenotypes based on ejection fraction. European Journal of Heart Failure, 20, pp. 1634-1635. (doi: 10.1002/ejhf.1325)

Campbell, R. T., Petrie, M. C., McMurray, J. J.V. (2018) Talking to patients with heart failure about end of life. European Journal of Heart Failure, 20, pp. 1763-1765. (doi: 10.1002/ejhf.1321)

Dobbin, S. J.H., Cameron, A. C., Petrie, M. C., Jones, R. J., Touyz, R. M., Lang, N. N. (2018) Toxicity of cancer therapy: what the cardiologist needs to know about angiogenesis inhibitors. Heart, 104, pp. 1995-2002. (doi: 10.1136/heartjnl-2018-313726)

Connolly, A., Kelly, A., Campos, F. O., Myles, R., Smith, G., Bishop, M. J. (2018) Ventricular endocardial tissue geometry affects stimulus threshold and effective refractory period. Biophysical Journal, 115, pp. 2486-2498. (doi: 10.1016/j.bpj.2018.11.003)

Streng, K. W., Nauta, J. F., Hillege, H. L., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Zannad, F., Damman, K., van der Meer, P., Voors, A. A. (2018) Non-cardiac comorbidities in heart failure with reduced, mid-range and preserved ejection fraction. International Journal of Cardiology, 271, pp. 132-139. (doi: 10.1016/j.ijcard.2018.04.001)

Santema, B. T., Kloosterman, M., Van Gelder, I. C., Mordi, I., Lang, C. C., Lam, C. S.P., Anker, S., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Ter Maaten, J. M., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zwinderman, A. H., Zannad, F., Damman, K., van der Meer, P., Rienstra, M., Voors, A. A. (2018) Comparing biomarker profiles of patients with heart failure: atrial fibrillation vs. sinus rhythm and reduced vs. preserved ejection fraction. European Heart Journal, 39, pp. 3867-3875. (doi: 10.1093/eurheartj/ehy421)

Cao, T. H., Jones, D. J. L., Quinn, P. A., Chan, D. C. S., Hafid, N., Parry, H. M., Mohan, M., Sandhu, J. K., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Metra, M., Ponikowski, P., Samani, N. J., Van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Voors, A. A., Lang, C. C., Ng, L. L. (2018) Using matrix assisted laser desorption ionisation mass spectrometry (MALDI-MS) profiling in order to predict clinical outcomes of patients with heart failure. Clinical Proteomics, 15, (doi: 10.1186/s12014-018-9213-1)

Kristensen, S. L., Rørth, R., Jhund, P. S., Shen, L., Lee, M. M.Y., Petrie, M. C., Køber, L., McMurray, J. J.V. (2018) Microvascular complications in diabetes patients with heart failure and reduced ejection fraction-insights from the Beta-blocker Evaluation of Survival Trial. European Journal of Heart Failure, 20, pp. 1549-1556. (doi: 10.1002/ejhf.1201)

Narang, R., Saxena, A., Desai, A., Ramakrishnan, S., Thangjam, R. S., Kulkarni, S., Narvencar, K., Jacques' e Costa, A. K., Dias, A., Sukharamwala, R., Cleland, J. (2018) Prevalence and determinants of hypertension in apparently healthy schoolchildren in India: a multi-center study. European Journal of Preventive Cardiology, 25, pp. 1775-1784. (doi: 10.1177/2047487318790056)

Ghouri, I. A., Kelly, A., Salerno, S., Garten, K., Stølen, T., Kemi, O.-J., Smith, G. L. (2018) Characterization of electrical activity in post-myocardial infarction scar tissue in rat hearts using multiphoton microscopy. Frontiers in Physiology, 9, (doi: 10.3389/fphys.2018.01454)

Zhang, J., Pellicori, P., Pan, D., Dierckx, R., Clark, A.L., Cleland, J.G.F. (2018) Dynamic risk stratification using serial measurements of plasma concentrations of natriuretic peptides in patients with heart failure. International Journal of Cardiology, 269, pp. 196-200. (doi: 10.1016/j.ijcard.2018.06.070)

Maack, C. et al. (2018) Treatments targeting inotropy. European Heart Journal, (doi: 10.1093/eurheartj/ehy600)

Zannad, F., Anker, S. D., Byra, W. M., Cleland, J. G.F., Fu, M., Gheorghiade, M., Lam, C. S.P., Mehra, M. R., Neaton, J. D., Nessel, C. C., Spiro, T. E., van Veldhuisen, D. J., Greenberg, B. (2018) Rivaroxaban in patients with heart failure, sinus rhythm, and coronary disease. New England Journal of Medicine, 379, pp. 1332-1342. (doi: 10.1056/NEJMoa1808848)

Rush, C. J., Campbell, R. T., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2018) Association is not causation: treatment effects cannot be estimated from observational data in heart failure. European Heart Journal, 39, pp. 3417-3438. (doi: 10.1093/eurheartj/ehy407)

Guzik, T. J., Antoniades, C., Baker, A. H., Harrison, D. G., Loughrey, C. M., Maffia, P., Murphy, E., Nicklin, S. A., Peter, K., Pearson, J., Casadei, B. (2018) What matters in Cardiovascular Research? Scientific discovery driving clinical delivery. Cardiovascular Research, 114, pp. 1565-1568. (doi: 10.1093/cvr/cvy214)

Shah, S. J. et al. (2018) One-year safety and clinical outcomes of a transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction in the reduce elevated left atrial pressure in patients with heart failure (REDUCE LAP-HF I) trial: a randomized clinical trial. JAMA Cardiology, 3, pp. 968-977. (doi: 10.1001/jamacardio.2018.2936)

van Meer, B. J., Sala, L., Tertoolen, L. G.J., Smith, G. L., Burton, F. L., Mummery, C. L. (2018) Quantification of muscle contraction in vitro and in vivo using MUSCLEMOTION software: from stem cell-derived cardiomyocytes to zebrafish and human hearts. Current Protocols in Human Genetics, 99, (doi: 10.1002/cphg.67)

Keene, D., Arnold, A., Shun-Shin, M. J., Howard, J. P., Sohaib, S. A., Moore, P., Tanner, M., Quereshi, N., Muthumala, A., Chandresekeran, B., Foley, P., Leyva, F., Adhya, S., Falaschetti, E., Tsang, H., Vijayaraman, P., Cleland, J. G.F., Stegemann, B., Francis, D. P., Whinnett, Z. I. (2018) Rationale and design of the randomized multicentre His Optimized Pacing Evaluated for Heart Failure (HOPE-HF) trial. ESC Heart Failure, 5, pp. 965-976. (doi: 10.1002/ehf2.12315)

Lees, J. S., McQuarrie, E. P., Mackinnon, B. (2018) Renal biopsy: it is time for pragmatism and consensus. Clinical Kidney Journal, 11, pp. 605-609. (doi: 10.1093/ckj/sfy075)

Halliday, B. P., Gulati, A., Ali, A., Newsome, S., Lota, A., Tayal, U., Vassiliou, V. S., Arzanauskaite, M., Izgi, C., Krishnathasan, K., Singhal, A., Chiew, K., Gregson, J., Frenneaux, M. P., Cook, S. A., Pennell, D. J., Collins, P., Cleland, J. G.F., Prasad, S. K. (2018) Sex and age-based differences in the natural history and outcome of dilated cardiomyopathy. European Journal of Heart Failure, 20, pp. 1392-1400. (doi: 10.1002/ejhf.1216)

Blinova, K., Dang, Q., Millard, D., Smith, G., Pierson, J., Guo, L., Brock, M., Lu, H. R., Kraushaar, U., Zeng, H., Shi, H., Zhang, X., Sawada, K., Osada, T., Kanda, Y., Sekino, Y., Pang, L., Feaster, T. K., Kettenhofen, R., Stockbridge, N., Strauss, D. G., Gintant, G. (2018) International multisite study of human-induced pluripotent stem cell-derived cardiomyocytes for drug proarrhythmic potential assessment. Cell Reports, 24, pp. 3582-3592. (doi: 10.1016/j.celrep.2018.08.079)

Cleland, J. G.F., Clark, R. A. (2018) Telehealth: delivering high-quality care for heart failure. Lancet, 392, pp. 990-991. (doi: 10.1016/S0140-6736(18)31995-0)

Christakoudi, S. et al. (2018) Steroid regulation: an overlooked aspect of tolerance and chronic rejection in kidney transplantation. Molecular and Cellular Endocrinology, 473, pp. 205-216. (doi: 10.1016/j.mce.2018.01.021)

Nagai, T., Sundaram, V., Rothnie, K., Quint, J. K., Shoaib, A., Shiraishi, Y., Kohsaka, S., Piper, S., McDonagh, T. A., Hardman, S. M. C., Goda, A., Mizuno, A., Kohno, T., Rigsby, A. S., Yoshikawa, T., Clark, A. L., Anzai, T., Cleland, J. G.F. (2018) Mortality after admission for heart failure in the United Kingdom compared to Japan. Open Heart, 5, (doi: 10.1136/openhrt-2018-000811)

Tromp, J., Westenbrink, B. D., Oowerkerk, W., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Lang, C. C., Ng, L. L., Zannad, F., Zwinderman, A. H., Hillege, H. L., van der Meer, P., Voors, A. A. (2018) Identifying pathophysiological mechanisms in heart failure with reduced versus preserved ejection fraction. Journal of the American College of Cardiology, 72, pp. 1081-1090. (doi: 10.1016/j.jacc.2018.06.050)

Williams, B. et al. (2018) 2018 ESC/ESH Guidelines for the management of arterial hypertension. European Heart Journal, 39, pp. 3021-3104. (doi: 10.1093/eurheartj/ehy339)

Panahi, M., Papanikolaou, A., Torabi, A., Zhang, J.-G., Khan, H., Vazir, A., Hasham, M. G., Cleland, J. G.F., Rosenthal, N. A., Harding, S. E., Sattler, S. (2018) Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition. Cardiovascular Research, 114, pp. 1445-1461. (doi: 10.1093/cvr/cvy145)

Findlay, M., MacIsaac, R., MacLeod, M. J., Metcalfe, W., Traynor, J. P., Dawson, J., Mark, P. B. (2018) Renal replacement modality and stroke risk in end-stage renal disease—a national registry study. Nephrology Dialysis Transplantation, 33, pp. 1564-1571. (doi: 10.1093/ndt/gfx291)

Gulati, A., Japp, A. G., Raza, S., Halliday, B. P., Jones, D. A., Newsome, S., Ismail, N. A., Morarji, K., Khwaja, J., Spath, N., Shakespeare, C., Kalra, P. R., Lloyd, G., Mathur, A., Cleland, J. G.F., Cowie, M. R., Assomull, R. G., Pennell, D. J., Ismail, T. F., Prasad, S. K. (2018) Absence of myocardial fibrosis predicts favorable long-term survival in new-onset heart failure: a cardiovascular magnetic resonance study. Circulation: Cardiovascular Imaging, 11, (doi: 10.1161/CIRCIMAGING.118.007722)

McDowell, K., Petrie, M. C., Raihan, N. A., Logue, J. (2018) Effects of intentional weight loss in patients with obesity and heart failure: a systematic review. Obesity Reviews, 19, pp. 1189-1204. (doi: 10.1111/obr.12707)

Carrick, D., Haig, C., Maznyczka, A. M., Carberry, J., Mangion, K., Ahmed, N., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Radjenovic, A., Welsh, P., Sattar, N., Wetherall, K., Oldroyd, K. G., Berry, C. (2018) Hypertension, microvascular pathology and prognosis after an acute myocardial infarction. Hypertension, 72, pp. 720-730. (doi: 10.1161/HYPERTENSIONAHA.117.10786)

McEntegart, M. B., Corcoran, D., Carrick, D., Clerfond, G., Sidik, N., Collison, D., Robertson, K. R., Shaukat, A., Watkins, S., Rocchicholi, P. R., Eteiba, H., Petrie, M. P., Lindsay, M. M., Oldroyd, K. G., Berry, C. (2018) Incidence of procedural myocardial infarction and cardiac magnetic resonance imaging-detected myocardial injury following percutaneous coronary intervention with rotational atherectomy. EuroIntervention, 14, pp. 819-823. (doi: 10.4244/EIJ-D-17-01077)

Findlay, M. D., Dawson, J., MacIsaac, R., Jardine, A. G., MacLeod, M. J., Metcalfe, W., Traynor, J. P., Mark, P. B. (2018) Inequality in care and differences in outcome following stroke in people with end stage renal disease: results from a national registry linkage analysis. Kidney International Reports, 3, pp. 1064-1076. (doi: 10.1016/j.ekir.2018.04.011)

Selby, N. M. et al. (2018) Magnetic resonance imaging biomarkers for chronic kidney disease: a position paper from the European Cooperation in Science and Technology Action PARENCHIMA. Nephrology Dialysis Transplantation, 33, pp. ii4-ii14. (doi: 10.1093/ndt/gfy152)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2018) Persistent iron within the infarct core after ST-segment elevation myocardial infarction: implications for left ventricular remodeling and health outcomes. JACC: Cardiovascular Imaging, 11, pp. 1248-1256. (doi: 10.1016/j.jcmg.2017.08.027)

Kammer, M., Heinzel, A., Mayer, G., Reindl-Schwaighofer, R., Hu, K., Perco, P., Eder, S., Rosivall, L., Mark, P. B., Ju, W., Kretzler, M., Gilmour, P., Wilson, J. M., Duffin, K. L., Abdalla, M., McCarthy, M. I., Heerspink, H. L., Wiecek, A., Gomez, M. F., Oberbauer, R. (2018) Validation of plasma biomarker candidates for the prediction of eGFR decline in patients with type 2 diabetes. Diabetes Care, 41, pp. 1947-1954. (doi: 10.2337/dc18-0532)

Streng, K. W., Voors, A. A., Hillege, H. L., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhusen, D. J., Zwinderman, A. H., Zannad, F., Damman, K., van der Meer, P., Lang, C. C. (2018) Waist-to-hip ratio and mortality in heart failure. European Journal of Heart Failure, 20, pp. 1269-1277. (doi: 10.1002/ejhf.1244)

Campbell, R. T., Petrie, M. C., Jackson, C. E., Jhund, P. S., Wright, A., Gardner, R. S., Sonecki, P., Pozzi, A., McSkimming, P., McConnachie, A., Finlay, F., Davidson, P., Denvir, M. A., Johnson, M. J., Hogg, K. J., McMurray, J. J.V. (2018) Which patients with heart failure should receive specialist palliative care? European Journal of Heart Failure, 20, pp. 1338-1347. (doi: 10.1002/ejhf.1240)

Gillis, K., Stevens, K. K., Bell, E., Patel, R. K., Jardine, A. G., Morris, S. T.W., Schneider, M. P., Delles, C., Mark, P. B. (2018) Ascorbic acid lowers central blood pressure and asymmetric dimethylarginine in chronic kidney disease. Clinical Kidney Journal, 11, pp. 532-539. (doi: 10.1093/ckj/sfx158)

Yew, S. N., Carrick, D., Corcoran, D., Ahmed, N., Carberry, J., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Oldroyd, K. G., Berry, C. (2018) Coronary thermodilution waveforms after acute reperfused ST‐segment–elevation myocardial infarction: relation to microvascular obstruction and prognosis. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.008957)

Wessler, J., Kaye, D., Gustafsson, F., Petrie, M. C., Hasenfuβ, G., Lam, C. S.P., Borlaug, B. A., Komtebedde, J., Feldman, T., Shah, S. J., Burkhoff, D. (2018) Impact of baseline hemodynamics on the effects of a transcatheter interatrial shunt device in heart failure with preserved ejection fraction. Circulation: Heart Failure, 11, (doi: 10.1161/CIRCHEARTFAILURE.117.004540)

Nagai, T., Sundaram, V., Shoaib, A., Shiraishi, Y., Kohsaka, S., Rothnie, K. J., Piper, S., McDonagh, T. A., Hardman, S. M.C., Goda, A., Mizuno, A., Sawano, M., Rigby, A. S., Quint, J. K., Yoshikawa, T., Clark, A. L., Anzai, T., Cleland, J. G.F. (2018) Validation of U.S. mortality prediction models for hospitalized heart failure in the United Kingdom and Japan. European Journal of Heart Failure, 20, pp. 1179-1190. (doi: 10.1002/ejhf.1210)

Solomon, S. D. et al. (2018) Baseline characteristics of patients with heart failure and preserved ejection fraction in the PARAGON-HF trial. Circulation: Heart Failure, 11, (doi: 10.1161/CIRCHEARTFAILURE.118.004962)

Welsh, P., Rankin, N., Li, Q., Mark, P. B., Würtz, P., Ala-Korpela, M., Marre, M., Poulter, N., Hamet, P., Chalmers, J., Woodward, M., Sattar, N. (2018) Circulating amino acids and the risk of macrovascular, microvascular, and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE trial. Diabetologia, 61, pp. 1581-1591. (doi: 10.1007/s00125-018-4619-x)

Palazzuoli, A., Ruocco, G., Beltrami, M., Nuti, R., Cleland, J. G. (2018) Combined use of lung ultrasound, B-type natriuretic peptide, and echocardiography for outcome prediction in patients with acute HFrEF and HFpEF. Clinical Research in Cardiology, 107, pp. 586-596. (doi: 10.1007/s00392-018-1221-7)

Nichols, S., Gleadall-Siddall, D.O., Antony, R., Clark, A.L., Cleland, J.G.F., Carroll, S., Ingle, L. (2018) Estimated peak functional capacity: an accurate method for assessing change in peak oxygen consumption after cardiac rehabilitation? Clinical Physiology and Functional Imaging, 38, pp. 681-688. (doi: 10.1111/cpf.12468)

Pellicori, P., Cleland, J. G.F., Clark, A. L. (2018) Losing track by tracking speckles. JACC: Cardiovascular Imaging, 11, pp. 1038-1039. (doi: 10.1016/j.jcmg.2018.04.027)

Sartor, F., Papini, G., Cox, L. G. E., Cleland, J. (2018) Methodological shortcomings of wrist-worn heart rate monitors validations. Journal of Medical Internet Research, 20, (doi: 10.2196/10108)

Ford, T. J., Corcoran, D., Oldroyd, K. G., McEntegart, M., Rocchiccioli, P., Watkins, S., Brooksbank, K., Padmanabhan, S., Sattar, N., Briggs, A., McConnachie, A., Touyz, R., Berry, C. (2018) Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Angina (CorMicA) stratified medicine clinical trial. American Heart Journal, 201, pp. 86-94. (doi: 10.1016/j.ahj.2018.03.010)

Bailey, E., McBride, M. W., McClure, J. D., Beattie, W., Graham, D., Dominiczak, A., Smith, C., Wardlaw, J. (2018) Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease. Clinical Science, 132, pp. 1315-1328. (doi: 10.1042/CS20171572)

Rørth, R., Jhund, P. S., Mogensen, U. M., Kristensen, S. L., Petrie, M. C., Køber, L., McMurray, J. J.V. (2018) Risk of incident heart failure in patients with diabetes and asymptomatic left ventricular systolic dysfunction. Diabetes Care, 41, pp. 1285-1291. (doi: 10.2337/dc17-2583)

Welsh, C., Welsh, P., Mark, P. B., Celis-Morales, C. A., Lewsey, J., Gray, S. R., Lyall, D. M., Iliodromiti, S., Gill, J. M.R., Pell, J., Jhund, P. S., Sattar, N. (2018) Association of total and differential leukocyte counts with cardiovascular disease and mortality in the UK Biobank. Arteriosclerosis, Thrombosis, and Vascular Biology, 38, pp. 1415-1423. (doi: 10.1161/ATVBAHA.118.310945)

Dickstein, K. et al. (2018) CRT Survey II: a European Society of Cardiology survey of cardiac resynchronisation therapy in 11 088 patients—who is doing what to whom and how? European Journal of Heart Failure, 20, pp. 1039-1051. (doi: 10.1002/ejhf.1142)

Høydal, M. A., Kirkeby-Garstad, I., Karevold, A., Wiseth, R., Haaverstad, R., Wahba, A., Stølen, T. L., Contu, R., Ellingsen, Ø., Smith, G. L. S., Kemi, O. J., Wisløff, U. (2018) Human cardiomyocyte calcium handling and transverse tubules in mid-stage of post-myocardial-infarction heart failure. ESC Heart Failure, 5, pp. 332-342. (doi: 10.1002/ehf2.12271)

Zymliński, R., Biegus, J., Sokolski, M., Siwołowski, P., Nawrocka-Millward, S., Todd, J., Jankowska, E. A., Banasiak, W., Cotter, G., Cleland, J. G., Ponikowski, P. (2018) Increased blood lactate is prevalent and identifies poor prognosis in patients with acute heart failure without overt peripheral hypoperfusion. European Journal of Heart Failure, 20, pp. 1011-1018. (doi: 10.1002/ejhf.1156)

Sliwa, K., Petrie, M. C., Hilfiker-Kleiner, D., Mebazaa, A., Jackson, A., Johnson, M. R., van der Meer, P., Mbakwem, A., Bauersachs, J. (2018) Long-term prognosis, subsequent pregnancy, contraception and overall management of peripartum cardiomyopathy: practical guidance paper from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European Journal of Heart Failure, 20, pp. 951-962. (doi: 10.1002/ejhf.1178)

Hernandez-Fuentes, M. P. et al. (2018) Long‐ and short‐term outcomes in renal allografts with deceased donors: a large recipient and donor genome‐wide association study. American Journal of Transplantation, 18, pp. 1370-1379. (doi: 10.1111/ajt.14594)

Bruegmann, T., Smith, G. L. (2018) Macrophages: new players in cardiac ageing? Cardiovascular Research, 114, pp. e47-e49. (doi: 10.1093/cvr/cvy047)

Perera, D., Clayton, T., Petrie, M. C., Greenwood, J. P., O'Kane, P. D., Evans, R., Sculpher, M., Mcdonagh, T., Gershlick, A., de Belder, M., Redwood, S., Carr-White, G., Marber, M. (2018) Percutaneous revascularization for ischemic ventricular dysfunction: rationale and design of the REVIVED-BCIS2 trial: percutaneous coronary intervention for ischemic cardiomyopathy. JACC: Heart Failure, 6, pp. 517-526. (doi: 10.1016/j.jchf.2018.01.024)

Sze, S., Pellicori, P., Kazmi, S., Rigby, A., Cleland, J. G.F., Wong, K., Clark, A. L. (2018) Prevalence and prognostic significance of malnutrition using 3 scoring systems among outpatients with heart failure: a comparison with body mass index. JACC: Heart Failure, 6, pp. 476-486. (doi: 10.1016/j.jchf.2018.02.018)

Corcoran, D., Ford, T. J., Hsu, L.-Y., Chiribiri, A., Orchard, V., Mangion, K., McEntegart, M., Rocchiccioli, P., Watkins, S., Good, R., Brooksbank, K., Padmanabhan, S., Sattar, N., McConnachie, A., Oldroyd, K. G., Touyz, R. M., Arai, A., Berry, C. (2018) Rationale and design of the Coronary Microvascular Angina Cardiac Magnetic Resonance imaging (CorCMR) diagnostic study: the CorMicA CMR sub-study. Open Heart, 5, (doi: 10.1136/openhrt-2018-000924)

Ambrosy, A. P., Mentz, R. J., Fiuzat, M., Cleland, J. G.F., Greene, S. J., O'Connor, C. M., Teerlink, J. R., Zannad, F., Solomon, S. D. (2018) The role of angiotensin receptor–neprilysin inhibitors in cardiovascular disease—existing evidence, knowledge gaps, and future directions. European Journal of Heart Failure, 20, pp. 963-972. (doi: 10.1002/ejhf.1159)

Rubio-Gracia, J., Demissei, B. G., ter Maaten, J. M., Cleland, J. G., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B. A., Givertz, M. M., Bloomfield, D. M., Dittrich, H., Damman, K., Pérez-Calvo, J. I., Voors, A. A. (2018) Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure. International Journal of Cardiology, 258, pp. 185-191. (doi: 10.1016/j.ijcard.2018.01.067)

Ferrari, R., Bueno, H., Chioncel, O., Cleland, J. G., Stough, W. G., Lettino, M., Metra, M., Parissis, J. T., Pinto, F., Ponikowski, P., Ruschitzka, F., Tavazzi, L. (2018) Acute heart failure: lessons learned, roads ahead. European Journal of Heart Failure, 20, pp. 842-850. (doi: 10.1002/ejhf.1169)

Salvi, D., Ottaviano, M., Muuraiskangas, S., Martınez-Romero, A., Vera-Munoz, C., Triantafyllidis, A., Cabrera Umpierrez, M. F., Arredondo Waldmeyer, M. T., Skobel, E., Knackstedt, C., Liedes, H., Honka, A., Luprano, J., Cleland, J. G.F., Stut, W., Deighan, C. (2018) An m-health system for education and motivation in cardiac rehabilitation: the experience of heartcycle guided exercise. Journal of Telemedicine and Telecare, 24, pp. 303-316. (doi: 10.1177/1357633X17697501)

Jackson, A. M., Dalzell, J. R., Walker, N. L., Coats, C. J., Jhund, P. S., Petrie, M. C. (2018) Peripartum cardiomyopathy: diagnosis and management. Heart, 104, pp. 779-786. (doi: 10.1136/heartjnl-2016-310599)

Beusekamp, J. C., Tromp, J., van der Wal, H. H., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Rossignol, P., Zannad, F., Voors, A. A., van der Meer, P. (2018) Potassium and the use of renin–angiotensin–aldosterone system inhibitors in heart failure with reduced ejection fraction. European Journal of Heart Failure, 20, pp. 923-930. (doi: 10.1002/ejhf.1079)

Metra, M., Cotter, G., Senger, S., Edwards, C., Cleland, J. G., Ponikowski, P., Cursack, G. C., Milo, O., Teerlink, J. R., Givertz, M. M., O’Connor, C. M., Dittrich, H. C., Bloomfield, D. M., Voors, A. A., Davison, B. A. (2018) Prognostic significance of creatinine increases during an acute heart failure admission in patients with and without residual congestion. Circulation: Heart Failure, 11, (doi: 10.1161/CIRCHEARTFAILURE.117.004644)

Evans, M., Grams, M., Sang, Y., Astor, B. C., Blankestijn, P. J., Brunskill, N. J., Collins, J. F., Kalra, P. A., Kovesdy, C. P., Levin, A., Mark, P. B., Moranne, O., Rao, P., Rios, P. G., Schneider, M. P., Shalev, V., Zhang, H., Chang, A. R., Gansevoort, R. T., Matsushita, K., Zhang, L., Eckardt, K.-U., Hemmelgarn, B., Wheeler, D. C. (2018) Risk factors for prognosis in patients with severely decreased GFR. Kidney International Reports, 3, pp. 625-637. (doi: 10.1016/j.ekir.2018.01.002)

Cosmi, F. et al. (2018) Treatment with insulin is associated with worse outcome in patients with chronic heart failure and diabetes. European Journal of Heart Failure, 20, pp. 888-895. (doi: 10.1002/ejhf.1146)

Seferović, P. M. et al. (2018) Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 20, pp. 853-872. (doi: 10.1002/ejhf.1170)

Kelly, A., Salerno, S., Connolly, A., Bishop, M., Charpentier, F., Stølen, T., Smith, G. L. (2018) Normal interventricular differences in tissue architecture underlie right ventricular susceptibility to conduction abnormalities in a mouse model of Brugada syndrome. Cardiovascular Research, 114, pp. 724-736. (doi: 10.1093/cvr/cvx244)

Boyden, P. A., Smith, G. L. (2018) Ca2+ leak, what is it? Why should we care? Can it be managed? Heart Rhythm, 15, pp. 607-614. (doi: 10.1016/j.hrthm.2017.11.018)

Fröhlich, H., Henning, F., Täger, T., Schellberg, D., Grundtvig, M., Goode, K., Corletto, A., Kazmi, S., Hole, T., Katus, H. A., Atar, D., Cleland, J. G.F., Agewall, S., Frankenstein, L., Clark, A. L. (2018) Comparative effectiveness of enalapril, lisinopril, and ramipril in the treatment of patients with chronic heart failure: a propensity score-matched cohort study. European Heart Journal: Cardiovascular Pharmacotherapy, 4, pp. 82-92. (doi: 10.1093/ehjcvp/pvx013)

Petrie, M. C., Rocchiccioli, P. (2018) Coronary angiography in heart failure: when and why? Uncertainty reigns. Heart, 104, pp. 548-549. (doi: 10.1136/heartjnl-2017-312200)

Ferreira, J. P., Rossignol, P., Demissei, B., Sharma, A., Girerd, N., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Voors, A., Zannad, F. (2018) Coronary angiography in worsening heart failure: determinants, findings and prognostic implications. Heart, 104, pp. 606-613. (doi: 10.1136/heartjnl-2017-311750)

Sokoreli, I., Pauws, S. C., Steyerberg, E. W., de Vries, G.-J., Riistama, J. M., Tesanovic, A., Kazmi, S., Pellicori, P., Cleland, J. G., Clark, A. L. (2018) Prognostic value of psychosocial factors for first and recurrent hospitalizations and mortality in heart failure patients: insights from the OPERA-HF study. European Journal of Heart Failure, 20, pp. 689-696. (doi: 10.1002/ejhf.1112)

Linde, C., Cleland, J. G.F., Gold, M. R., Daubert, J. C., Tang, A. S.L., Young, J. B., Sherfesee, L., Abraham, W. T. (2018) The interaction of sex, height, and QRS duration on the effects of cardiac resynchronization therapy on morbidity and mortality: an individual-patient data meta-analysis. European Journal of Heart Failure, 20, pp. 780-791. (doi: 10.1002/ejhf.1133)

Lang, N. N., Walker, N. L. (2018) Adult congenital heart disease and radiation exposure: the malignant price of cardiac care. Circulation, 137, pp. 1346-1348. (doi: 10.1161/CIRCULATIONAHA.117.032815)

Lee, M. M.Y. et al. (2018) Non-Invasive Versus Invasive Management in Patients With Prior Coronary Artery Bypass Surgery With a Non-ST Segment Elevation Acute Coronary Syndrome: Comparisons Between the Randomized Controlled Pilot Trial and Registry. (doi: 10.1016/S0735-1097(18)30586-2)

Malmo, V., Kelly, A., Garten, K. S., Stolen, T., Rolim, N. P. L., Wisloff, U., Smith, G., Loennechen, J. P. (2018) Aerobic interval training prevents age-dependent vulnerability to atrial fibrillation in rodents. Frontiers in Physiology, 9, (doi: 10.3389/fphys.2018.00206)

Gho, J. M.I.H., Schmidt, A. F., Pasea, L., Koudstaal, S., Pujades-Rodriguez, M., Denaxas, S., Shah, A. D., Patel, R. S., Gale, C. P., Hoes, A. W., Cleland, J. G., Hemingway, H., Asselbergs, F. W. (2018) An electronic health records cohort study on heart failure following myocardial infarction in England: incidence and predictors. BMJ Open, 8, (doi: 10.1136/bmjopen-2017-018331)

Stewart, R. A.H., Szalewska, D., Stebbins, A., Al-Khalidi, H. R., Cleland, J. G.H., Rynkiewicz, A., Drazner, M. H., White, H. D., Mark, D. B., Roy, A., Kosevic, D., Rajda, M., Jasinski, M., Leng, C. Y., Tungsubutra, W., Desvigne-Nickens, P., Velazquez, E. J., Petrie, M. C. (2018) Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy. Open Heart, 5, (doi: 10.1136/openhrt-2017-000752)

Petrie, M. C., Connelly, D. T., Gardner, R. S. (2018) Who needs an implantable cardioverter-defibrillator? Controversies and opportunities after DANISH. European Journal of Heart Failure, 20, pp. 413-416. (doi: 10.1002/ejhf.1135)

Velazquez, E. J., Petrie, M. C. (2018) CABG or PCI for diabetic patients with left ventricular dysfunction: closing in on the truth? Journal of the American College of Cardiology, 71, pp. 828-831. (doi: 10.1016/j.jacc.2018.01.014)

ter Maaten, J. M., Voors, A. A., Damman, K., van der Meer, P., Anker, S. D., Cleland, J. G.F., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Navis, G., Ng, L., Ouwerkerk, W., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., de Borst, M. H. (2018) Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure. International Journal of Cardiology, 253, pp. 84-90. (doi: 10.1016/j.ijcard.2017.10.010)

Conrad, N., Judge, A., Tran, J., Mohseni, H., Hedgecott, D., Crespillo, A. P., Allison, M., Hemingway, H., Cleland, J. G., McMurray, J. J.V., Rahimi, K. (2018) Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals. Lancet, 391, pp. 10-16. (doi: 10.1016/S0140-6736(17)32520-5)

Sala, L. et al. (2018) MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo. Circulation Research, 122, pp. e5-e16. (doi: 10.1161/CIRCRESAHA.117.312067)

Persu, A. et al. (2018) Blood pressure response to renal denervation is correlated with baseline blood pressure variability: a patient-level meta-analysis. Journal of Hypertension, 36, pp. 221-229. (doi: 10.1097/HJH.0000000000001582)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Numé, A.-k., Gislason, G. H.,, Jhund, P. S., Petrie, M. C., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure. European Journal of Heart Failure, 20, pp. 240-247. (doi: 10.1002/ejhf.1046)

Mark, P., Dekkers, I., Blankestijn, P., Leiner, T., Roditi, G. (2018) Letter on 'European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis' Journal of the European Academy of Dermatology and Venereology, 32, pp. e84-e85. (doi: 10.1111/jdv.14774)

Cleland, J. G.F. (2018) Physicians Addicted to Prescribing Aspirin-a Disorder Of Cardiologists (PAPA-DOC) Syndrome: the headache of nonevidence-based medicine for ischemic heart disease? JACC: Heart Failure, 6, pp. 168-171. (doi: 10.1016/j.jchf.2017.11.014)

Nikolaidou, T., Pellicori, P., Zhang, J., Kazmi, S., Goode, K. M., Cleland, J. G., Clark, A. L. (2018) Prevalence, predictors, and prognostic implications of PR interval prolongation in patients with heart failure. Clinical Research in Cardiology, 107, pp. 108-119. (doi: 10.1007/s00392-017-1162-6)

Emmens, J. E., Jones, D. J.L., Cao, T. H., Chan, D. C.S., Romaine, S. P.R., Quinn, P. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M., de Boer, R. A., Voors, A. A., Ng, L. L. (2018) Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure. European Journal of Heart Failure, 20, pp. 260-267. (doi: 10.1002/ejhf.1101)

Cotter, G., Metra, M., Davison, B. A., Jondeau, G., Cleland, J. G.F., Bourge, R. C., Milo, O., O'Connor, C. M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2018) Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? European Journal of Heart Failure, 20, pp. 317-322. (doi: 10.1002/ejhf.889)

Stoumpos, S., Lees, J., Welsh, P., Hund, M., Geddes, C. C., Nelson, S. M., Mark, P. B. (2018) The utility of anti-Müllerian hormone in women with chronic kidney disease, on haemodialysis and after kidney transplantation. Reproductive BioMedicine Online, 36, pp. 219-226. (doi: 10.1016/j.rbmo.2017.11.003)

Taylor, A. H.M., Rankin, A. J., McQuarrie, E. P., Freel, M., Homer, N. Z.M., Andrew, R., Jardine, A. G., Mark, P. B. (2018) Non-uniform relationship between salt status and aldosterone activity in patients with chronic kidney disease. Clinical Science, 132, pp. 285-294. (doi: 10.1042/CS20171603)

Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C. C., van der Harst, P., Filippatos, G., Dickstein, K., Cleland, J. G., Anker, S. D., Voors, A. A. (2018) Biomarker-guided versus guideline-based treatment of patients with heart failure: results from BIOSTAT-CHF. Journal of the American College of Cardiology, 71, pp. 386-398. (doi: 10.1016/j.jacc.2017.11.041)

Feldman, T., Mauri, L., Kahwash, R., Litwin, S., Ricciardi, M. J., van der Harst, P., Penicka, M., Fail, P. S., Kaye, D. M., Petrie, M. C., Basuray, A., Hummel, S. L., Forde-McLean, R., Nielsen, C. D., Lilly, S., Massaro, J. M., Burkhoff, D., Shah, S. J. (2018) Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial. Circulation, 137, pp. 364-375. (doi: 10.1161/CIRCULATIONAHA.117.032094)

Cleland, J. G.F., Flather, M. D., Altman, D. G., Kotecha, D. (2018) Reply: an incomplete story. Journal of the American College of Cardiology, 71, pp. 105. (doi: 10.1016/j.jacc.2017.10.078)

McCarroll, C. S. et al. (2018) Runx1 deficiency protects against adverse cardiac remodeling after myocardial infarction. Circulation, 137, pp. 57-70. (doi: 10.1161/CIRCULATIONAHA.117.028911)

Cleland, J. G.F., Bunting, K. V., Flather, M. D., Altman, D. G., Holmes, J., Coats, A. J.S., Manzano, L., McMurray, J. J.V., Ruschitzka, F., van Veldhuisen, D. J., von Lueder, T. G., Böhm, M., Andersson, B., Kjekshus, J., Packer, M., Rigby, A. S., Rosano, G., Wedel, H., Hjalmarson, Å., Wikstrand, J., Kotecha, D. (2018) Beta-blockers for heart failure with reduced, mid-range, and preserved ejection fraction: an individual patient-level analysis of double-blind randomized trials. European Heart Journal, 39, pp. 26-35. (doi: 10.1093/eurheartj/ehx564)

Solbu, M. D., Mjøen, G., Mark, P. B., Holdaas, H., Fellström, B., Schmieder, R. E., Zannad, F., Herrington, W. G., Jardine, A. G. (2018) Predictors of atherosclerotic events in patients on haemodialysis: post hoc analyses from the AURORA Study. Nephrology Dialysis Transplantation, 33, pp. 102-112. (doi: 10.1093/ndt/gfw360)

Mark, P. B. (2018) Strategies to manage cardiovascular risk in chronic kidney disease. Nephrology Dialysis Transplantation, 33, pp. 23-25. (doi: 10.1093/ndt/gfx329)

Mangion, K., McDowell, K., Mark, P. B., Rutherford, E. (2018) Characterizing cardiac involvement in chronic kidney disease using CMR—a systematic review. Current Cardiovascular Imaging Reports, 11, (doi: 10.1007/s12410-018-9441-9)

Pellicori, P., Urbinati, A., Zhang, J., Joseph, A. C., Costanzo, P., Lukaschuk, E., Capucci, A., Cleland, J. G.F., Clark, A. L. (2018) Clinical and prognostic relationships of pulmonary artery to aorta diameter ratio in patients with heart failure: a cardiac magnetic resonance imaging study. Clinical Cardiology, 41, pp. 20-27. (doi: 10.1002/clc.22840)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)

Stoumpos, S., Hennessy, M., Vesey, A. T., Radjenovic, A., Kasthuri, R., Kingsmore, D. B., Mark, P. B., Roditi, G. (2018) Ferumoxytol-enhanced magnetic resonance angiography for the assessment of potential kidney transplant recipients. European Radiology, 28, pp. 115-123. (doi: 10.1007/s00330-017-4934-5)

Lee, M. M.Y. et al. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial. (doi: 10.1136/heartjnl-2018-BCIS.9)

Eder, S., Leierer, J., Kerschbaum, J., Rosivall, L., Wiecek, A., de Zeeuw, D., Mark, P. B., Heinze, G., Rossing, P., Heerspink, H. L., Mayer, G. (2018) A prospective cohort study in patients with type 2 diabetes mellitus for validation of biomarkers (PROVALID) –study design and baseline characteristics. Kidney and Blood Pressure Research, 43, pp. 181-190. (doi: 10.1159/000487500)

Lachaud, Q., MacQuaide, N., Burton, F., Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model. Biophysical Journal, 114, pp. 625A. (doi: 10.1016/j.bpj.2017.11.3377)

Rørth, R., Fosbøl, E. L., Kragholm, K., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study. Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795)

Layland, J., Tong, D., Lee, M., Berry, C. (2018) ST and T-Wave Abnormality as Footprint of Myocardial Oedema in Non–ST-Elevation Myocardial Infarction. (doi: 10.1016/j.hlc.2018.06.515)

Bouabdallaoui, N. et al. (2018) Society of Thoracic Surgeons risk score and EuroSCORE-2 appropriately assess 30-day postoperative mortality in the STICH trial and a contemporary cohort of patients with left ventricular dysfunction undergoing surgical revascularization. Circulation: Heart Failure, 11, (doi: 10.1161/circheartfailure.118.005531)

2017

Berry, C., McClure, J. D., Oldroyd, K. G. (2017) Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution. Circulation, 136, pp. 2389-2391. (doi: 10.1161/CIRCULATIONAHA.117.030430)

Lei, C. L., Wang, K., Clerx, M., Johnstone, R. H., Hortigon-Vinagre, M. P., Zamora, V., Allan, A., Smith, G. L., Gavaghan, D. J., Mirams, G. R., Polonchuk, L. (2017) Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology. Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00986)

Duncan, G., Firth, K., George, V., Hoang, M. D., Staniforth, A., Smith, G., Denning, C. (2017) Drug-mediated shortening of action potentials in LQTS2 human induced pluripotent stem cell-derived cardiomyocytes. Stem Cells and Development, 26, pp. 1695-1705. (doi: 10.1089/scd.2017.0172)

Kaye, D. M., Silvestry, F. E., Gustafsson, F., Cleland, J. G., van Veldhuisen, D. J., Ponikowski, P., Komtebedde, J., Nanayakkara, S., Burkhoff, D., Shah, S. J. (2017) Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction. European Journal of Heart Failure, 19, pp. 1690-1697. (doi: 10.1002/ejhf.930)

Hilfiker-Kleiner, D., Haghikia, A., Masuko, D., Nonhoff, J., Held, D., Libhaber, E., Petrie, M. C., Walker, N. L., Podewski, E., Berliner, D., Bauersachs, J., Sliwa, K. (2017) Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. European Journal of Heart Failure, 19, pp. 1723-1728. (doi: 10.1002/ejhf.808)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)

Kristensen, S. L., Jhund, P. S., Lee, M. M.Y., Køber, L., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., McMurray, J. J.V. (2017) Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes. Cardiovascular Drugs and Therapy, 31, pp. 545-549. (doi: 10.1007/s10557-017-6754-x)

Wang, G., Durussel, J., Shurlock, J., Mooses, M., Fuku, N., Bruinvels, G., Pedlar, C., Burden, R., Murray, A., Yee, B., Keenan, A., McClure, J. D., Sottas, P.-E., Pitsiladis, Y. P. (2017) Validation of whole-blood transcriptome signature during microdose recombinant human erythropoietin (rHuEpo) administration. BMC Genomics, 18, (doi: 10.1186/s12864-017-4191-7)

Rutherford, E., Stewart, G., Houston, J. G., Jardine, A. G., Mark, P. B., Struthers, A. D. (2017) An open-label dose-finding study of allopurinol to target defined reduction in urate levels in hemodialysis patients. Journal of Clinical Pharmacology, 57, pp. 1409-1414. (doi: 10.1002/jcph.939)

Holman, R. R., Coleman, R. L., Chan, J. C. N., Chiasson, J.-L., Feng, H., Ge, J., Gerstein, H. C., Gray, R., Huo, Y., Lang, Z., McMurray, J. J., Rydén, L., Schröder, S., Sun, Y., Theodorakis, M. J., Tendera, M., Tucker, L., Tuomilehto, J., Wei, Y., Yang, W., Wang, D., Hu, D., Pan, C., ACE Study Group, (2017) Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5, pp. 877-886. (doi: 10.1016/S2213-8587(17)30309-1)

Wong, C. M., Hawkins, N. M., Ezekowitz, J. A., Jhund, P. S., Savu, A., MacDonald, M. R., Kristensen, S. L., Petrie, M. C., McMurray, J. J.V., McAlister, F. A., Kaul, P. (2017) Heart failure in young adults is associated with high mortality: a contemporary population-level analysis. Canadian Journal of Cardiology, 33, pp. 1472-1477. (doi: 10.1016/j.cjca.2017.05.009)

Rutherford, E., Mangion, K., Mccomb, C., Bell, E., Cockburn, S., Talle, M., Roditi, G., Welsh, P., Woodward, R., Radjenovic, A., Struthers, A. D., Jardine, A., Berry, C., Patel, R. K., Mark, P. B. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, (doi: 10.1038/s41598-017-14481-y)

Bayes-Genis, A., Núñez, J., Zannad, F., Ferreira, J. P., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Lang, C. C., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Metra, M., Lupón, J., Voors, A. A. (2017) The PCSK9-LDL receptor axis and outcomes in heart failure: BIOSTAT-CHF subanalysis. Journal of the American College of Cardiology, 70, pp. 2128-2136. (doi: 10.1016/j.jacc.2017.08.057)

Sharma, A., Demissei, B. G., Tromp, J., Hillege, H. L., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Davison, B. A., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van Veldhuisen, D. J., Cotter, G., Ezekowitz, J. A., Khan, M. A.F., Voors, A. A. (2017) A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure. European Journal of Heart Failure, 19, pp. 1310-1320. (doi: 10.1002/ejhf.912)

Rankin, A. J., Rankin, S. H. (2017) Cardioverting acute atrial fibrillation and the risk of thromboembolism: not all patients are created equal. Clinical Medicine, 17, pp. 419-423. (doi: 10.7861/clinmedicine.17-5-419)

Stevens, K., Denby, L., Patel, R. K., Mark, P. B., Kettlewell, S., Smith, G. L., Clancy, M. J., Delles, C., Jardine, A. G. (2017) Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway. Nephrology Dialysis Transplantation, 32, pp. 1617-1627. (doi: 10.1093/ndt/gfw252)

Ferreira, J. P., Rossignol, P., Machu, J.-L., Sharma, A., Girerd, N., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Hillege, H. L., Lang, C. C., Ter Maaten, J., Metra, M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Voors, A., Zannad, F. (2017) Mineralocorticoid receptor antagonist pattern of use in heart failure with reduced ejection fraction: findings from BIOSTAT-CHF. European Journal of Heart Failure, 19, pp. 1284-1293. (doi: 10.1002/ejhf.900)

Nassif, M. E., Tang, Y., Cleland, J. G.F., Abraham, W. T., Linde, C., Gold, M. R., Young, J. B., Daubert, J. C., Sherfesee, L., Schaber, D., Tang, A. S.L., Jones, P. G., Arnold, S. V., Spertus, J. A. (2017) Precision medicine for cardiac resynchronization: predicting quality of life benefits for individual patients-an analysis from 5 clinical trials. Circulation: Heart Failure, 10, (doi: 10.1161/CIRCHEARTFAILURE.117.004111)

Cleland, J. G.F., Halliday, B. P., Prasad, S. K. (2017) Selecting patients with nonischemic dilated cardiomyopathy for ICDs. Journal of the American College of Cardiology, 70, pp. 1228-1231. (doi: 10.1016/j.jacc.2017.07.748)

Noh, R. M., Venkatasubramanian, S., Daga, S., Langrish, J., Mills, N. L., Lang, N. N., Hoffmann, E., Waterhouse, B., Newby, D. E., Frier, B. M. (2017) Cardiometabolic effects of a novel SIRT1 activator, SRT2104, in people with type 2 diabetes mellitus. Open Heart, 4, (doi: 10.1136/openhrt-2017-000647)

Lu, H.R., Hortigon-Vinagre, M.P., Zamora, V., Kopljar, I., De Bondt, A., Gallacher, D.J., Smith, G. (2017) Application of optical action potentials in human induced pluripotent stem cells-derived cardiomyocytes to predict drug-induced cardiac arrhythmias. Journal of Pharmacological and Toxicological Methods, 87, pp. 53-67. (doi: 10.1016/j.vascn.2017.05.001)

Fröhlich, H., Torres, L., Täger, T., Schellberg, D., Corletto, A., Kazmi, S., Goode, K., Grundtvig, M., Hole, T., Katus, H. A., Cleland, J. G.F., Atar, D., Clark, A. L., Agewall, S., Frankenstein, L. (2017) Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure. Clinical Research in Cardiology, 106, pp. 711-721. (doi: 10.1007/s00392-017-1115-0)

Sliwa, K., Mebazaa, A., Hilfiker-Kleiner, D., Petrie, M. C., Maggioni, A. P., Laroche, C., Regitz-Zagrosek, V., Schaufelberger, M., Tavazzi, L., van der Meer, P., Roos-Hesselink, J. W., Seferovic, P., van Spandonck-Zwarts, K., Mbakwem, A., Böhm, M., Mouquet, F., Pieske, B., Hall, R., Ponikowski, P., Bauersachs, J. (2017) Clinical characteristics of patients from the worldwide registry on peripartum cardiomyopathy (PPCM) European Journal of Heart Failure, 19, pp. 1131-1141. (doi: 10.1002/ejhf.780)

Saxena, P., Hortigon-Vinagre, M.P., Beyl, S., Baburin, I., Andranovits, S., Iqbal, S.M., Costa, A., IJzerman, A.P., Kügler, P., Timin, E., Smith, G.L., Hering, S. (2017) Correlation between human ether-a-go-go-related gene channel inhibition and action potential prolongation. British Journal of Pharmacology, 174, pp. 3081-3093. (doi: 10.1111/bph.13942)

Cleland, J. G.F. (2017) Does aspirin detract from the benefits of mineralocorticoid receptor antagonists in patients with heart failure and a reduced left ventricular ejection fraction? Probably! European Journal of Heart Failure, 19, pp. 1086-1088. (doi: 10.1002/ejhf.697)

Koudstaal, S., Pujades-Rodriguez, M., Denaxas, S., Gho, J. M.I.H., Shah, A. D., Yu, N., Patel, R. S., Gale, C. P., Hoes, A. W., Cleland, J. G.F., Asselbergs, F. W., Hemingway, H. (2017) Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people. European Journal of Heart Failure, 19, pp. 1119-1127. (doi: 10.1002/ejhf.709)

Sanders, M. F., van Doormaal, P. J., Beeftink, M. M.A., Bots, M. L., Fadl Elmula, F. E. M., Habets, J., Hammer, F., Hoffmann, P., Jacobs, L., Mark, P. B., Persu, A., Renkin, J., Roditi, G., Spiering, W., Staessen, J. A., Taylor, A. H., Verloop, W. L., Vink, E. E., Vonken, E.-J., Voskuil, M., Leiner, T., Blankestijn, P. J. (2017) Renal artery and parenchymal changes after renal denervation: assessment by magnetic resonance angiography. European Radiology, 27, pp. 3934-3941. (doi: 10.1007/s00330-017-4770-7)

Murphy, S. R., Wang, L., Wang, Z., Domondon, P., Lang, D., Habecker, B. A., Myles, R. C., Ripplinger, C. M. (2017) β-adrenergic inhibition prevents action potential and calcium handling changes during regional myocardial ischemia. Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00630)

Gimpelewicz, C., Metra, M., Cleland, J. G.F., Szecsödy, P., Chang Wun, C.-C., Boer-Martins, L., Cotter, G., Davison, B. A., Felker, G. M., Filippatos, G., Greenberg, B. H., Pang, P., Ponikowski, P., Severin, T., Voors, A. A., Teerlink, J. R. (2017) Effects of serelaxin on the outcome of patients with or without substantial peripheral edema: a subgroup analysis from the RELAX-AHF trial. American Heart Journal, 190, pp. 113-122. (doi: 10.1016/j.ahj.2017.05.012)

Linde, C., Abraham, W. T., Gold, M. R., Daubert, C., Tang, A. S.L., Young, J. B., Sherfesee, L., Hudnall, H., Fagan, D. H., Cleland, J. G. (2017) Predictors of short-term clinical response to cardiac resynchronization therapy. European Journal of Heart Failure, 19, pp. 1056-1063. (doi: 10.1002/ejhf.795)

Touyz, R. M., Lang, N. N., Herrmann, J., van den Meiracker, A. H., Danser, A.H. J. (2017) Recent advances in hypertension and cardiovascular toxicities with vascular endothelial growth factor inhibition. Hypertension, 70, pp. 220-226. (doi: 10.1161/HYPERTENSIONAHA.117.08856)

Lees, J. S., McQuarrie, E. P., Mordi, N., Geddes, C. C., Fox, J. G., Mackinnon, B. (2017) Risk factors for bleeding complications after nephrologist-performed native renal biopsy. Clinical Kidney Journal, 10, pp. 573-577. (doi: 10.1093/ckj/sfx012)

Cleland, J. G.F. (2017) What do cardiology and homeopathy have in common? : A belief in aspirin? JACC: Heart Failure, 5, pp. 611-614. (doi: 10.1016/j.jchf.2017.06.009)

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Cameron, A. C., Lang, N. N., Touyz, R. M. (2017) Cardiovascular complications from cancer therapy: hypertension-focus on vascular endothelial growth factor inhibitors. Elesvier

Arain, F., Gullestad, L., Nymo, S., Kjekshus, J., Cleland, J. G.F., Michelsen, A., McMurray, J. J.V., Wikstrand, J., Aukrust, P., Ueland, T. (2017) Low YKL-40 in Chronic Heart Failure may predict beneficial effects of statins: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA) Biomarkers, 22, pp. 261-267. (doi: 10.1080/1354750X.2016.1204003)

2016

Torabi, A., Cleland, J. G.F., Sherwi, N., Atkin, P., Panahi, H., Kilpatrick, E., Thackray, S., Hoye, A., Alamgir, F., Goode, K., Rigby, A., Clark, A. L. (2016) Influence of case definition on incidence and outcome of acute coronary syndromes. Open Heart, 3, (doi: 10.1136/openhrt-2016-000487)

Fattah, C., Nather, K., McCarroll, C. S., Hortigon-Vinagre, M. P., Zamora Rodriguez, V., Flores-Munoz, M., McArthur, L., Zentilin, L., Giacca, M., Touyz, R. M., Smith, G. L., Loughrey, C. M., Nicklin, S. A. (2016) Gene therapy with Angiotensin-(1-9) preserves left ventricular systolic function after myocardial infarction. Journal of the American College of Cardiology, 68, pp. 2652-2666. (doi: 10.1016/j.jacc.2016.09.946)

Huethorst, E., Hortigon, M., Zamora-Rodriguez, V., Reynolds, P.M., Burton, F., Smith, G., Gadegaard, N. (2016) Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate. ACS Biomaterials Science and Engineering, 2, pp. 2231-2239. (doi: 10.1021/acsbiomaterials.6b00426)

Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Solomon, S. D., Adams, Jr., K. F., Cleland, J. G.F., Ezekowitz, J. A., Goudev, A., Macdonald, P., Metra, M., Mitrovic, V., Ponikowski, P., Serpytis, P., Spinar, J., Tomcsányi, J., Vandekerckhove, H. J., Voors, A. A., Monsalvo, M. L., Johnston, J., Malik, F. I., Honarpour, N. (2016) Chronic oral study of myosin activation to increase contractility in heart failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial. Lancet, 388, pp. 2895-2903. (doi: 10.1016/S0140-6736(16)32049-9)

Carrick, D., Haig, C., Ahmed, N., Carberry, J., Teng Yue May, V., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davies, A., Abouzaid, A. M., Mordi, I., Ford, I., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment elevation myocardial infarction. Circulation, 134, pp. 1833-1847. (doi: 10.1161/CIRCULATIONAHA.116.022603)

Vegter, E. L., Schmitter, D., Hagemeijer, Y., Ovchinnikova, E. S., van der Harst, P., Teerlink, J. R., O'Connor, C. M., Metra, M., Davison, B. A., Bloomfield, D., Cotter, G., Cleland, J. G.F., Givertz, M. M., Ponikowski, P., van Veldhuisen, D. J., van der Meer, P., Berezikov, E., Voors, A. A., Khan, M. A.F. (2016) Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure. International Journal of Cardiology, 224, pp. 231-239. (doi: 10.1016/j.ijcard.2016.09.010)

Rebollo-Mesa, I. et al. (2016) Biomarkers of tolerance in kidney transplantation - are we predicting tolerance or response to immunosuppressive treatment? American Journal of Transplantation, 16, pp. 3443-3457. (doi: 10.1111/ajt.13932)

Pellicori, P., Cleland, J. G.F., Zhang, J., Kallvikbacka-Bennett, A., Urbinati, A., Shah, P., Kazmi, S., Clark, A. L. (2016) Cardiac dysfunction, congestion and loop diuretics: their relationship to prognosis in heart failure. Cardiovascular Drugs and Therapy, 30, pp. 599-609. (doi: 10.1007/s10557-016-6697-7)

Kaye, D. M., Hasenfuß, G., Neuzil, P., Post, M. C., Doughty, R., Trochu, J.-N., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Walton, A., Muller, D., Walters, D., Hausleiter, J., Raake, P., Petrie, M. C., Bergmann, M., Jondeau, G., Feldman, T., van Veldhuisen, D. J., Ponikowski, P., Silvestry, F. E., Burkhoff, D., Hayward, C. (2016) One-year outcomes after transcatheter insertion of an interatrial shunt device for the management of heart failure with preserved ejection fraction. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003662)

Hortigon-Vinagre, M.P., Zamora, V., Burton, F.L., Green, J., Gintant, G.A., Smith, G.L. (2016) The use of ratiometric fluorescence measurements of the voltage sensitive dye Di-4-ANEPPS to examine action potential characteristics and drug effects on human induced pluripotent stem cell-derived cardiomyocytes. Toxicological Sciences, 154, pp. 320-331. (doi: 10.1093/toxsci/kfw171)

Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2016) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Heart, 103, pp. 255-257. (doi: 10.1136/heartjnl-2015-309191)

Demissei, B. G., Postmus, D., Liu, L. C.Y., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B. A., Edwards, C., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Voors, A. A., Hillege, H. L. (2016) Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure — Post-hoc analysis of the PROTECT trial. International Journal of Cardiology, 223, pp. 967-975. (doi: 10.1016/j.ijcard.2016.08.271)

Ferreira, J. P., Girerd, N., Pellicori, P., Duarte, K., Girerd, S., Pfeffer, M. A., McMurray, J. J.V., Pitt, B., Dickstein, K., Jacobs, L., Staessen, J. A., Butler, J., Latini, R., Masson, S., Mebazaa, A., Rocca, H. P. B.-L., Delles, C., Heymans, S., Sattar, N., Jukema, J. W., Cleland, J. G.F., Zannad, F., Rossignol, P. (2016) Renal function estimation and Cockroft–Gault formulas for predicting cardiovascular mortality in population-based, cardiovascular risk, heart failure and post-myocardial infarction cohorts: the Heart ‘OMics’ in AGEing (HOMAGE) and the high-risk myocardial infarction database initiatives. BMC Medicine, 14, (doi: 10.1186/s12916-016-0731-2)

Weinberger, F., Breckwoldt, K., Pecha, S., Kelly, A., Geertz, B., Starbatty, J., Yorgan, T., Cheng, K.-H., Lessmann, K., Stolen, T., Scherrer-Crosbie, M., Smith, G., Reichenspurner, H., Hansen, A., Eschenhagen, T. (2016) Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells. Science Translational Medicine, 8, pp. 363ra148-363ra148. (doi: 10.1126/scitranslmed.aaf8781)

Bekfani, T., Pellicori, P., Morris, D. A., Ebner, N., Valentova, M., Steinbeck, L., Wachter, R., Elsner, S., Sliziuk, V., Schefold, J. C., Sandek, A., Doehner, W., Cleland, J. G.F., Lainscak, M., Anker, S. D., von Haehling, S. (2016) Sarcopenia in patients with heart failure with preserved ejection fraction: impact on muscle strength, exercise capacity and quality of life. International Journal of Cardiology, 222, pp. 41-46. (doi: 10.1016/j.ijcard.2016.07.135)

Petrie, M. C., Jhund, P. S., She, L., Adlbrecht, C., Doenst, T., Panza, J. A., Hill, J. A., Lee, K. L., Rouleau, J. L., Prior, D. L., Ali, I. S., Maddury, J., Golba, K. S., White, H. D., Carson, P., Chrzanowski, L., Romanov, A., Miller, A. B., Velazquez, E. J. (2016) Ten-year outcomes after coronary artery bypass grafting according to age in patients with heart failure and left ventricular systolic dysfunction: an analysis of the extended follow-up of the STICH Trial (Surgical Treatment for Ischemic Heart Failure) Circulation, 134, pp. 1314-1324. (doi: 10.1161/CIRCULATIONAHA.116.024800)

Hennigan, B., Oldroyd, K. G., Berry, C., Johnson, N., McClure, J., McCartney, P., McEntegart, M. B., Eteiba, H., Petrie, M. C., Rocchiccioli, P., Good, R., Lindsay, M. M., Hood, S., Watkins, S. (2016) Discordance between resting and hyperemic indices of coronary stenosis severity: the VERIFY 2 study (a comparative study of resting coronary pressure gradient, instantaneous wave-free ratio and fractional flow reserve in an unselected population referred for invasive angiography) Circulation: Cardiovascular Interventions, 9, (doi: 10.1161/CIRCINTERVENTIONS.116.004016)

Mangion, K., Clerfond, G., Mccomb, C., Carrick, D., Rauhalammi, S. M., McClure, J., Corcoran, D. S., Woodward, R., Orchard, V., Radjenovic, A., Zhong, X., Berry, C. (2016) Myocardial strain in healthy adults across a broad age range as revealed by cardiac magnetic resonance imaging at 1.5 and 3.0T: associations of myocardial strain with myocardial region, age, and sex. Journal of Magnetic Resonance Imaging, 44, pp. 1197-1205. (doi: 10.1002/jmri.25280)

Crocini, C., Ferrantini, C., Coppini, R., Scardigli, M., Yan, P., Loew, L. M., Smith, G., Cerbai, E., Poggesi, C., Pavone, F. S., Sacconi, L. (2016) Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation. Scientific Reports, 6, (doi: 10.1038/srep35628)

Tromp, J., Meyer, S., Mentz, R. J., O'Connor, C. M., Metra, M., Dittrich, H. C., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., van der Meer, P. (2016) Acute heart failure in the young: clinical characteristics and biomarker profiles. International Journal of Cardiology, 221, pp. 1067-1072. (doi: 10.1016/j.ijcard.2016.06.339)

Ross, P. D., Guy, J., Selfridge, J., Kamal, B., Bahey, N., Tanner, E., Gillingwater, T. H., Jones, R. A., Loughrey, C. M., McCarroll, C. S., Bailey, M. E.S., Bird, A., Cobb, S. (2016) Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics, 25, pp. 4389-4404. (doi: 10.1093/hmg/ddw269)

Rørth, R., Wong, C., Kragholm, K., Fosbøl, E. L., Mogensen, U. M., Lamberts, M., Petrie, M. C., Jhund, P. S., Gerds, T. A., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2016) Return to the workforce following first hospitalization for heart failure: a Danish nationwide cohort study. Circulation, 134, pp. 999-1009. (doi: 10.1161/CIRCULATIONAHA.116.021859)

Sokoreli, I., de Vries, J.J.G., Riistama, J.M., Pauws, S.C., Steyerberg, E.W., Tesanovic, A., Geleijnse, G., Goode, K.M., Crundall-Goode, A., Kazmi, S., Cleland, J.G.F., Clark, A.L. (2016) Depression as an independent prognostic factor for all-cause mortality after a hospital admission for worsening heart failure. International Journal of Cardiology, 220, pp. 202-207. (doi: 10.1016/j.ijcard.2016.06.068)

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Cameron, A. C., Lang, N. N., Touyz, R. M. (2016) Drug treatment of hypertension: focus on vascular health. Drugs, 76, pp. 1529-1550. (doi: 10.1007/s40265-016-0642-8)

Herrington, W. G., Emberson, J., Mihaylova, B., Blackwell, L., Reith, C., Solbu, M. D., Mark, P. B., Fellström, B., Jardine, A. G., Wanner, C., Holdaas, H., Fulcher, J., Haynes, R., Landray, M. J., Keech, A., Simes, J., Collins, R., Baigent, C. (2016) Impact of renal function on the effects of LDL cholesterol lowering with statin-based regimens: a meta-analysis of individual participant data from 28 randomised trials. Lancet Diabetes and Endocrinology, 4, pp. 829-839. (doi: 10.1016/S2213-8587(16)30156-5)

Cleland, J. G.F., Pellicori, P. (2016) PARADIGM-HF: does dose matter? European Journal of Heart Failure, 18, pp. 1235-1237. (doi: 10.1002/ejhf.634)

Cotter, G., Davison, B. A., Milo, O., Bourge, R. C., Cleland, J. G.F., Jondeau, G., Krum, H., O'Connor, C. M., Metra, M., Parker, J. D., Torre-Amione, G., van Veldhuisen, D. J., Kobrin, I., Rainisio, M., Senger, S., Edwards, C., McMurray, J. J.V., Teerlink, J. R. (2016) Predictors and associations with outcomes of length of hospital stay in patients with acute heart failure: results from VERITAS. Journal of Cardiac Failure, 22, pp. 815-822. (doi: 10.1016/j.cardfail.2015.12.017)

Currie, G., Taylor, A. H.M., Fujita, T., Ohtsu, H., Lindhart, M., Rossing, P., Boesby, L., Edwards, N. C., Ferro, C. J., Townend, J. N., van den Meiracker, A. H., Saklayen, M. G., Oveisi, S., Jardine, A. G., Delles, C., Preiss, D. J., Mark, P. B. (2016) Effect of mineralocorticoid receptor antagonists on proteinuria and progression of chronic kidney disease: a systematic review and meta-analysis. BMC Nephrology, 17, (doi: 10.1186/s12882-016-0337-0)

Stirrat, C. G., Venkatasubramanian, S., Pawade, T., Mitchell, A. J., Shah, A. S., Lang, N. N., Newby, D. E. (2016) Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure. British Journal of Clinical Pharmacology, 82, pp. 974-982. (doi: 10.1111/bcp.13033)

Bauersachs, J., Arrigo, M., Hilfiker-Kleiner, D., Veltmann, C., Coats, A. J.S., Crespo-Leiro, M. G., De Boer, R. A., van der Meer, P., Maack, C., Mouquet, F., Petrie, M. C., Piepoli, M. F., Regitz-Zagrosek, V., Schaufelberger, M., Seferovic, P., Tavazzi, L., Ruschitzka, F., Mebazaa, A., Sliwa, K. (2016) Current management of patients with severe acute peripartum cardiomyopathy: practical guidance from the Heart Failure Association of the European Society of Cardiology Study Group on peripartum cardiomyopathy. European Journal of Heart Failure, 18, pp. 1096-1105. (doi: 10.1002/ejhf.586)

Rauhalammi, S. M.O., Mangion, K., Barrientos, P. H., Carrick, D. J.A., Clerfond, G., McClure, J., McComb, C., Radjenovic, A., Berry, C. (2016) Native myocardial longitudinal (T1) relaxation time: Regional, age, and sex associations in the healthy adult heart. Journal of Magnetic Resonance Imaging, 44, pp. 541-548. (doi: 10.1002/jmri.25217)

Hawkins, N. M., Jhund, P. S., Pozzi, A., O'Meara, E., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., Petrie, M. C., Virani, S., McMurray, J. J.V. (2016) Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non-vitamin K antagonist oral anticoagulant dose adjustment. European Journal of Heart Failure, 18, pp. 1162-1171. (doi: 10.1002/ejhf.614)

ter Maaten, J. M., Damman, K., Hanberg, J. S., Givertz, M. M., Metra, M., O’Connor, C. M., Teerlink, J. R., Ponikowski, P., Cotter, G., Davison, B., Cleland, J. G.F., Bloomfield, D. M., Hillege, H. L., van Veldhuisen, D. J., Voors, A. A., Testani, J. M. (2016) Hypochloremia, diuretic resistance, and outcome in patients with acute heart failure. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003109)

Carberry, J., Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Remote zone extracellular volume and left ventricular remodeling in survivors of st-elevation myocardial infarction. Hypertension, 68, pp. 385-391. (doi: 10.1161/HYPERTENSIONAHA.116.07222)

Bhattacharyya, S., Mittal, T., Abayalingam, M., Kabir, T., Dalby, M., Cleland, J. G.F., Baltabaeva, A., Rahman Haley, S. (2016) Classification of aortic stenosis by flow and gradient patterns provides insights into the pathophysiology of disease. Angiology, 67, pp. 664-669. (doi: 10.1177/0003319715611804)

Fröhlich, H., Nelges, C., Täger, T., Schwenger, V., Cebola, R., Schnorbach, J., Goode, K. M., Kazmi, S., Katus, H. A., Cleland, J. G.F., Clark, A. L., Frankenstein, L. (2016) Long-term changes of renal function in relation to ace inhibitor/angiotensin receptor blocker dosing in patients with heart failure and chronic kidney disease. American Heart Journal, 178, pp. 28-36. (doi: 10.1016/j.ahj.2016.03.024)

Davison, B. A., Metra, M., Senger, S., Edwards, C., Milo, O., Bloomfield, D. M., Cleland, J. G., Dittrich, H. C., Givertz, M. M., O'Connor, C. M., Massie, B. M., Ponikowski, P., Teerlink, J. R., Voors, A. A., Cotter, G. (2016) Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality. European Journal of Heart Failure, 18, pp. 1041-1050. (doi: 10.1002/ejhf.540)

Cleland, J. G.F., Zhang, J., Pellicori, P., Dicken, B., Dierckx, R., Shoaib, A., Wong, K., Rigby, A., Goode, K., Clark, A. L. (2016) Prevalence and outcomes of anemia and hematinic deficiencies in patients with chronic heart failure. JAMA Cardiology, 1, pp. 539-547. (doi: 10.1001/jamacardio.2016.1161)

Findlay, M. D., Thomson, P. C., Macisaac, R., Jardine, A. G., Patel, R. K., Stevens, K. K., Rutherford, E., Clancy, M., Geddes, C. C., Dawson, J., Mark, P. B. (2016) Risk factors and outcome of stroke in renal transplant recipients. Clinical Transplantation, 30, pp. 918-924. (doi: 10.1111/ctr.12765)

Wanner, C., Inzucchi, S. E., Lachin, J. M., Fitchett, D., von Eynatten, M., Mattheus, M., Johansen, O. E., Woerle, H. J., Broedl, U. C., Zinman, B., EMPA-REG OUTCOME Investigators, (2016) Empagliflozin and progression of kidney disease in type 2 diabetes. New England Journal of Medicine, 375, pp. 323-334. (doi: 10.1056/NEJMoa1515920)

Biegus, J., Hillege, H. L., Postmus, D., Valente, M. A.E., Bloomfield, D. M., Cleland, J. G.F., Cotter, G., Davison, B. A., Dittrich, H. C., Fiuzat, M., Givertz, M. M., Massie, B. M., Metra, M., Teerlink, J. R., Voors, A. A., O'Connor, C. M., Ponikowski, P. (2016) Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study. European Journal of Heart Failure, 18, pp. 830-839. (doi: 10.1002/ejhf.532)

Høydal, M. A., Stølen, T. O., Kettlewell, S., Maier, L. S., Brown, J. H., Sowa, T., Catalucc, D., Condorelli, G., Kemi, O. J., Smith, G. L., Wisløff, U. (2016) Exercise training reverses myocardial dysfunction induced by CaMKIIδC overexpression by restoring Ca2+-homeostasis. Journal of Applied Physiology, 121, pp. 212-220. (doi: 10.1152/japplphysiol.00188.2016)

Feldman, T., Komtebedde, J., Burkhoff, D., Massaro, J., Maurer, M. S., Leon, M. B., Kaye, D., Silvestry, F. E., Cleland, J. G.F., Kitzman, D., Kubo, S. H., Van Veldhuisen, D. J., Kleber, F., Trochu, J.-N., Auricchio, A., Gustafsson, F., Hasenfuβ, G., Ponikowski, P., Filippatos, G., Mauri, L., Shah, S. J. (2016) Transcatheter interatrial shunt device for the treatment of heart failure: rationale and design of the randomized trial to REDUCE elevated left atrial pressure in heart failure (REDUCE LAP-HF I) Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003025)

Voors, A. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., ter Maaten, J. M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M. (2016) A systems BIOlogy Study to TAilored treatment in chronic heart failure: rationale, design, and baseline characteristics of BIOSTAT-CHF. European Journal of Heart Failure, 18, pp. 716-726. (doi: 10.1002/ejhf.531)

ter Maaten, J. M., Valente, M. A.E., Damman, K., Cleland, J. G., Givertz, M. M., Metra, M., O’Connor, C. M., Teerlink, J. R., Ponikowski, P., Bloomfield, D. M., Cotter, G., Davison, B., Subacius, H., van Veldhuisen, D. J., van der Meer, P., Hillege, H. L., Gheorghiade, M., Voors, A. A. (2016) Combining diuretic response and hemoconcentration to predict rehospitalization after admission for acute heart failure. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.115.002845)

Emmens, J. E., ter Maaten, J. M., Matsue, Y., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Todd, J., van Veldhuisen, D. J., Hillege, H. L., Damman, K., van der Meer, P., Voors, A. A. (2016) Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome. European Journal of Heart Failure, 18, pp. 641-649. (doi: 10.1002/ejhf.426)

Baumert, M., Porta, A., Vos, M. A., Malik, M., Couderc, J.-P., Laguna, P., Piccirillo, G., Smith, G. L., Tereshchenko, L. G., Volders, P. G.A. (2016) QT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESC Working Group on Cardiac Cellular Electrophysiology. Europace, 18, pp. 925-944. (doi: 10.1093/europace/euv405)

Sharp, A. S. P. et al. (2016) Renal artery sympathetic denervation: observations from the UK experience. Clinical Research in Cardiology, 105, pp. 544-552. (doi: 10.1007/s00392-015-0959-4)

Pedersen, C. M., Venkatasubramanian, S., Vase, H., Hyldebrandt, J. A., Contractor, H., Schmidt, M. R., Bøtker, H. E., Cruden, N. L., Newby, D. E., Kharbanda, R. K., Lang, N. N. (2016) Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury. British Journal of Clinical Pharmacology, 81, pp. 1037-1045. (doi: 10.1111/bcp.12882)

Carrick, D., Haig, C., Carberry, J., Teng Tue May, V., Mccartney, P., Welsh, P., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Mahrous, A., Rauhalammi, S. M.O., Mordi, I., Ford, I., Radjenovic, A., Sattar, N., Oldroyd, K. G., Berry, C. (2016) Microvascular resistance of the culprit coronary artery in acute ST-elevation myocardial infarction. JCI Insight, 1, (doi: 10.1172/jci.insight.85768)

Pellicori, P., Goode, K. M., Nicholls, R., Ahmed, D., Clark, A. L., Cleland, J. G.F. (2016) Regional circulatory distribution of novel cardiac bio-markers and their relationships with haemodynamic measurements. International Journal of Cardiology, 210, pp. 149-155. (doi: 10.1016/j.ijcard.2016.02.081)

Gheorghiade, M., Larson, C. J., Shah, S. J., Greene, S. J., Cleland, J. G.F., Colucci, W. S., Dunnmon, P., Epstein, S. E., Kim, R. J., Parsey, R. V., Stockbridge, N., Carr, J., Dinh, W., Krahn, T., Kramer, F., Wahlander, K., Deckelbaum, L. I., Crandall, D., Okada, S., Senni, M., Sikora, S., Sabbah, H. N., Butler, J. (2016) Developing new treatments for heart failure: focus on the heart. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.115.002727)

Venkatasubramanian, S., Noh, R. M., Daga, S., Langrish, J. P., Mills, N. L., Waterhouse, B. R., Hoffmann, E., Jacobson, E. W., Lang, N. N., Frier, B. M., Newby, D. E. (2016) Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus. Open Heart, 3, (doi: 10.1136/openhrt-2016-000402)

Shoaib, A., Farag, M., Nasir, M., John, J., Gupta, S., Pellicori, P., Antony, R., Perveen, R., Rigby, A., Goode, K. M., Yassin, A., Clark, A. L., Cleland, J. G.F. (2016) Is the diagnostic coding position of acute heart failure related to mortality? A report from the Euro Heart Failure Survey-1. European Journal of Heart Failure, 18, pp. 556-563. (doi: 10.1002/ejhf.505)

Pellicori, P., Cleland, J.G.F. (2016) New ways to visualize and combat congestion in heart failure = Nuevos modos de visualizar y combatir la congestión en la insuficiencia cardiaca. Revista Clínica Española, 216, pp. 202-204. (doi: 10.1016/j.rce.2016.03.007)

Nisbet, A. M., Camelliti, P., Walker, N. L., Burton, F. L., Cobbe, S. M., Kohl, P., Smith, G. L. (2016) Prolongation of atrio-ventricular node conduction in a rabbit model of ischaemic cardiomyopathy: role of fibrosis and connexin remodelling. Journal of Molecular and Cellular Cardiology, 94, pp. 54-64. (doi: 10.1016/j.yjmcc.2016.03.011)

Campbell, R. T., Willox, G. P., Jhund, P. S., Hawkins, N. M., Huang, F., Petrie, M. C., McMurray, J. J. V. (2016) Reporting of lost to follow-up and treatment discontinuation in device and pharmacotherapy trials in chronic heart failure: a systematic review. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.115.002842)

Velazquez, E. J., Lee, K. L., Jones, R. H., Al-Khalidi, H. R., Hill, J. A., Panza, J. A., Michler, R. E., Bonow, R. O., Doenst, T., Petrie, M. C., Oh, J. K., She, L., Moore, V. L., Desvigne-Nickens, P., Sopko, G., Rouleau, J. L. (2016) Coronary-artery bypass surgery in patients with ischemic cardiomyopathy. New England Journal of Medicine, 374, pp. 1511-1520. (doi: 10.1056/NEJMoa1602001)

Kotecha, D., Manzano, L., Krum, H., Rosano, G., Holmes, J., Altman, D. G., Collins, P. D., Packer, M., Wikstrand, J., Coats, A. J.S., Cleland, J. G.F., Kirchhof, P., von Lueder, T. G., Rigby, A. S., Andersson, B., Lip, G. Y.H., van Veldhuisen, D. J., Shibata, M. C., Wedel, H., Böhm, M., Flather, M. D. (2016) Effect of age and sex on efficacy and tolerability of β blockers in patients with heart failure with reduced ejection fraction: individual patient data meta-analysis. British Medical Journal, 353, (doi: 10.1136/bmj.i1855)

Lee, M. M.Y., Petrie, M. C., Rocchiccioli, P., Simpson, J., Jackson, C., Brown, A., Corcoran, D., Mangion, K., McEntegart, M., Shaukat, A., Rae, A., Hood, S., Peat, E., Findlay, I., Murphy, C., Cormack, A., Bukov, N., Balachandran, K., Papworth, R., Ford, I., Briggs, A., Berry, C. (2016) Non-invasive versus invasive management in patients with prior coronary artery bypass surgery with a non-ST segment elevation acute coronary syndrome: study design of the pilot randomised controlled trial and registry (CABG-ACS) Open Heart, 3, (doi: 10.1136/openhrt-2015-000371)

Abdul-Rahim, A. H., MacIsaac, R. L., Jhund, P. S., Petrie, M. C., Lees, K. R., McMurray, J. J.V. (2016) Efficacy and safety of digoxin in patients with heart failure and reduced ejection fraction according to diabetes status: An analysis of the Digitalis Investigation Group (DIG) trial. International Journal of Cardiology, 209, pp. 310-316. (doi: 10.1016/j.ijcard.2016.02.074)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Lindsay, M., Mahrous, A., Ford, I., Tzemos, N., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Prognostic significance of infarct core pathology revealed by quantitative non-contrast in comparison to contrast cardiac magnetic resonance imaging in reperfused ST-elevation myocardial infarction survivors. European Heart Journal, 37, pp. 1044-1059. (doi: 10.1093/eurheartj/ehv372)

Diver, L. A., MacKenzie, S. M., Fraser, R., McManus, F., Freel, E. M., Alvarez-Madrazo, S., McClure, J. D., Friel, E. C., Hanley, N. A., Dominiczak, A. F., Caulfield, M. J., Munroe, P. B., Connell, J. M., Davies, E. (2016) Common polymorphisms at the CYP17A1 locus associate with steroid phenotype: support for blood pressure genome-wide association study signals at this locus. Hypertension, 67, pp. 724-732. (doi: 10.1161/HYPERTENSIONAHA.115.06925)

Ovchinnikova, E. S. et al. (2016) Signature of circulating microRNAs in patients with acute heart failure. European Journal of Heart Failure, 18, pp. 414-423. (doi: 10.1002/ejhf.332)

Teerlink, J. R., Felker, G. M., McMurray, J. J.V., Ponikowski, P., Metra, M., Filippatos, G. S., Ezekowitz, J. A., Dickstein, K., Cleland, J. G.F., Kim, J. B., Lei, L., Knusel, B., Wolff, A. A., Malik, F. I., Wasserman, S. M. (2016) Acute treatment with omecamtiv mecarbil to increase contractility in acute heart failure. Journal of the American College of Cardiology, 67, pp. 1444-1455. (doi: 10.1016/j.jacc.2016.01.031)

Hasenfuß, G., Hayward, C., Burkhoff, D., Silvestry, F. E., McKenzie, S., Gustafsson, F., Malek, F., Van der Heyden, J., Lang, I., Petrie, M. C., Cleland, J. G.F., Leon, M., Kaye, D. M. (2016) A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial. Lancet, 387, pp. 1298-1304. (doi: 10.1016/S0140-6736(16)00704-2)

Durussel, J., Haile, D., Mooses, K., Daskalaki, E., Beattie, W., Mooses, M., Mekonen, W., Ongaro, N., Anjila, E., Patel, R., Padmanabhan, N., McBride, M., McClure, J., Pitsiladis, Y. (2016) Blood transcriptional signature of recombinant human erythropoietin administration and implications for antidoping strategies. Physiological Genomics, 48, pp. 202-209. (doi: 10.1152/physiolgenomics.00108.2015)

Damman, K., Kjekshus, J., Wikstrand, J., Cleland, J. G.F., Komajda, M., Wedel, H., Waagstein, F., McMurray, J. J.V. (2016) Loop diuretics, renal function and clinical outcome in patients with heart failure and reduced ejection fraction. European Journal of Heart Failure, 18, pp. 328-336. (doi: 10.1002/ejhf.462)

Demissei, B. G., Valente, M. A.E., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van der Meer, P., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A. (2016) Optimizing clinical use of biomarkers in high-risk acute heart failure patients. European Journal of Heart Failure, 18, pp. 269-280. (doi: 10.1002/ejhf.443)

Cuba Gyllensten, I., Bonomi, A. G., Goode, K. M., Reiter, H., Habetha, J., Amft, O., Cleland, J. G.F. (2016) Early indication of decompensated heart failure in patients on home-telemonitoring: a comparison of prediction algorithms based on daily weight and noninvasive transthoracic bio-impedance. JMIR Medical Informatics, 4, (doi: 10.2196/medinform.4842)

Demissei, B. G., Cleland, J. G.F., O'Connor, C. M., Metra, M., Ponikowski, P., Teerlink, J. R., Davison, B., Givertz, M. M., Bloomfield, D. M., Dittrich, H., van Veldhuisen, D. J., Hillege, H. L., Voors, A. A., Cotter, G. (2016) Procalcitonin-based indication of bacterial infection identifies high risk acute heart failure patients. International Journal of Cardiology, 204, pp. 164-171. (doi: 10.1016/j.ijcard.2015.11.141)

ter Maaten, J. M., Valente, M. A.E., Metra, M., Bruno, N., O’Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., van Veldhuisen, D. J., Hillege, H. L., Damman, K., Voors, A. A. (2016) A combined clinical and biomarker approach to predict diuretic response in acute heart failure. Clinical Research in Cardiology, 105, pp. 145-153. (doi: 10.1007/s00392-015-0896-2)

Gardner, R. T., Ripplinger, C. M., Myles, R., Habecker, B. A. (2016) Molecular mechanisms of sympathetic remodeling and arrhythmias. Circulation: Arrhythmia and Electrophysiology, 9, (doi: 10.1161/circep.115.001359)

Bhandari, S., Ives, N., Brettell, E. A., Valente, M., Cockwell, P., Topham, P. S., Cleland, J. G.F., Khwaja, A., El Nahas, M. (2016) Multicentre randomized controlled trial of angiotensin-converting enzyme inhibitor/angiotensin receptor blocker withdrawal in advanced renal disease: the STOP-ACEi trial. Nephrology Dialysis Transplantation, 31, pp. 255-261. (doi: 10.1093/ndt/gfv346)

Carrick, D., Haig, C., Rauhalammi, S., Clerfond, G., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Mahrous, A., Welsh, P., Sattar, N., Ford, I., Oldroyd, K., Radjenovic, A., Berry, C. (2016) Temporal evolution of myocardial hemorrhage and edema in patients after acute ST-elevation myocardial infarction: pathophysiologic insights and clinical implications. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.115.002834)

Watt, J., Kennedy, S., Ahmed, N., Hayhurst, J., McClure, J. D., Berry, C., Wadsworth, R. M., Oldroyd, K. G. (2016) The relationship between oxidised LDL, endothelial progenitor cells and coronary endothelial function in patients with CHD. Open Heart, 3, (doi: 10.1136/openhrt-2015-000342)

Bruno, N., ter Maaten, J. M., Ovchinnikova, E. S., Vegter, E. L., Valente, M. A.E., van der Meer, P., de Boer, R. A., van der Harst, P., Schmitter, D., Metra, M., O'Connor, C. M., Ponikowski, P., Teerlink, J. R., Cotter, G., Davison, B., Cleland, J. G.F., Givertz, M. M., Bloomfield, D. M., Dittrich, H. C., Pinto, Y. M., van Veldhuisen, D. J., Hillege, H. L., Berezikov, E., Voors, A. A. (2016) MicroRNAs relate to early worsening of renal function in patients with acute heart failure. International Journal of Cardiology, 203, pp. 564-569. (doi: 10.1016/j.ijcard.2015.10.217)

Zhang, J., Hobkirk, J., Carroll, S., Pellicori, P., Clark, A. L., Cleland, J. G.F. (2016) Exploring quality of life in patients with and without heart failure. International Journal of Cardiology, 202, pp. 676-684. (doi: 10.1016/j.ijcard.2015.09.076)

Ahmed, N., Layland, J., Carrick, D., Petrie, M. C., McEntegart, M., Eteiba, H., Hood, S., Lindsay, M., Watkins, S., Davie, A., Mahrous, A., Carberry, J., Teng, V., McConnachie, A., Curzen, N., Oldroyd, K. G., Berry, C. (2016) Safety of guidewire-based measurement of fractional flow reserve and the index of microvascular resistance using intravenous adenosine in patients with acute or recent myocardial infarction. International Journal of Cardiology, 202, pp. 305-310. (doi: 10.1016/j.ijcard.2015.09.014)

Jenkins, P., Sng, S., Brooksbank, K., Brooksbank, A.J. (2016) Socioeconomic deprivation and age are barriers to the online collection of patient reported outcome measures in orthopaedic patients. Annals of the Royal College of Surgeons of England, 98, pp. 40-44. (doi: 10.1308/rcsann.2016.0007)

Cowie, M. R., Bax, J., Bruining, N., Cleland, J. G.F., Koehler, F., Malik, M., Pinto, F., van der Velde, E., Vardas, P. (2016) e-Health: a position statement of the European Society of Cardiology. European Heart Journal, 37, pp. 63-66. (doi: 10.1093/eurheartj/ehv416)

Ponikowski, P., Voors, A. A., Anker, S. D., Bueno, H., Cleland, J. G.F., Coats, A. J.S., Falk, V., González-Juanatey, J. R., Harjola, V.-P., Jankowska, E. A., Jessup, M., Linde, C., Nihoyannopoulos, P., Parissis, J. T., Pieske, B., Riley, J. P., Rosano, G. M.C., Ruilope, L. M., Ruschitzka, F., Rutten, F. H., van der Meer, P., McMurray, J. J.V., Petrie, M. C. (2016) 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 37, pp. 2129-2200. (doi: 10.1093/eurheartj/ehw128)

Boulberdaa, M., Scott, E., Ballantyne, M., Garcia, R., Descamps, B., Angelini, G. D., Brittan, M., Hunter, A., McBride, M., McClure, J., Miano, J. M., Emanueli, C., Mills, N. L., Mountford, J. C., Baker, A. H. (2016) A role for the long non-coding RNA SENCR in commitment and function of endothelial cells. Molecular Therapy, 24, pp. 978-990. (doi: 10.1038/mt.2016.41)

Stirrat, C. t., Alam, S. R., MacGillivray, T. J., Gray, C. D., Forsythe, R., Dweck, M. R., Payne, J. R., Prasad, S. K., Petrie, M. C., Gardner, R. S., Mirsadraee, S., Henriksen, P. A., Newby, D. E., Semple, S. I.K. (2016) Ferumoxytol-enhanced magnetic resonance imaging methodology and normal values at 1.5 and 3T. Journal of Cardiovascular Magnetic Resonance, 18, (doi: 10.1186/s12968-016-0261-2)

Mangion, K., Carrick, D., Hennigan, B. W., Payne, A. R., McClure, J., Mason, M., Das, R., Wilson, R., Edwards, R. J., Petrie, M. C., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2016) Infarct size and left ventricular remodelling after preventive percutaneous coronary intervention. Heart, 102, pp. 1980-1987. (doi: 10.1136/heartjnl-2015-308660)

Carrick, D., Haig, C., Watkins, S., Ahmed, N., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M. M., Davie, A., Mahrous, A., Mordi, I., Rauhalammi, S., Sattar, N., Welsh, P., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction. Circulation: Cardiovascular Imaging, 9, (doi: 10.1161/CIRCIMAGING.115.004148)

Gillis, K. A., Mccomb, C., Patel, R. K., Stevens, K. K., Schneider, M. P., Radjenovic, A., Morris, S. T.W., Roditi, G. H., Delles, C., Mark, P. B. (2016) Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease. Nephron, 133, pp. 183-192. (doi: 10.1159/000447601)

Stoumpos, S., McNeill, S. H., Gorrie, M., Mark, P. B., Brennand, J. E., Geddes, C. C., Deighan, C. J. (2016) Obstetric and long-term kidney outcomes in renal transplant recipients: a 40 year single-centre study. Clinical Transplantation, 30, pp. 673-681. (doi: 10.1111/ctr.12732)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., Anker, S. D., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J. V. (2016) The incremental prognostic and clinical value of multiple novel biomarkers in heart failure. European Journal of Heart Failure, 18, pp. 1491-1498. (doi: 10.1002/ejhf.543)

Emdin, C. A., Conrad, N., Kiran, A., Salimi-Khorshidi, G., Woodward, M., Anderson, S. G., Mohseni, H., Dargie, H. J., Hardman, S. M.C., McDonagh, T., McMurray, J. J.V., Cleland, J. G.F., Rahimi, K. (2016) Variation in hospital performance for heart failure management in the National Heart Failure Audit for England and Wales. Heart, 103, pp. 55-62. (doi: 10.1136/heartjnl-2016-309706)

Rutherford, E., Mark, P. (2016) What does STOP-IgAN tell us about how to treat IgA nephropathy? Journal of the Royal College of Physicians of Edinburgh, 46, pp. 23-25. (doi: 10.4997/JRCPE.2016.107)

2015

Cameron, A. C., Touyz, R. M., Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32, pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023)

Cleland, J. G.F., Mareev, Y. (2015) CRT for heart failure and ESRD: more trials or more thought needed? Journal of the American College of Cardiology, 66, pp. 2630-2632. (doi: 10.1016/j.jacc.2015.10.022)

Solbu, M. D., Thomson, P. C., Macpherson, S., Findlay, M. D., Stevens, K. K., Patel, R. K., Padmanabhan, S., Jardine, A. G., Mark, P. B. (2015) Serum phosphate and social deprivation independently predict all-cause mortality in chronic kidney disease. BMC Nephrology, 16, (doi: 10.1186/s12882-015-0187-1)

Nam, J., Briggs, A., Layland, J., Oldroyd, K. G., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Eteiba, H., Petrie, M. C., Lindsay, M., Watkins, S., Corbett, S., O'Rourke, B., O'Donnell, A., Stewart, A., Hannah, A., McConnachie, A., Henderson, R., Berry, C. (2015) Fractional flow reserve (FFR) versus angiography in guiding management to optimise outcomes in non-ST segment elevation myocardial infarction (FAMOUS-NSTEMI) developmental trial: cost-effectiveness using a mixed trial- and model-based methods. Cost Effectiveness and Resource Allocation, 2015, (doi: 10.1186/s12962-015-0045-9)

Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., Broedl, U. C., Inzucchi, S. E., EMPA-REG OUTCOME Investigators, (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. New England Journal of Medicine, 373, pp. 2117-2128. (doi: 10.1056/NEJMoa1504720)

Jolicœur, E. M., Dunning, A., Castelvecchio, S., Dabrowski, R., Waclawiw, M. A., Petrie, M. C., Stewart, R., Jhund, P. S., Desvigne-Nickens, P., Panza, J. A., Bonow, R. O., Sun, B., San, T. R., Al-Khalidi, H. R., Rouleau, J. L., Velazquez, E. J., Cleland, J. G.F. (2015) Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction. Journal of the American College of Cardiology, 66, pp. 2092-2100. (doi: 10.1016/j.jacc.2015.08.882)

Simpson, J., Castagno, D., Doughty, R. N., Poppe, K. K., Earle, N., Squire, I., Richards, M., Andersson, B., Ezekowitz, J. A., Komajda, M., Petrie, M. C., McAlister, F. A., Gamble, G. D., Whalley, G. A., McMurray, J. J.V. (2015) Is heart rate a risk marker in patients with chronic heart failure and concomitant atrial fibrillation? Results from the MAGGIC meta-analysis. European Journal of Heart Failure, 17, pp. 1182-1191. (doi: 10.1002/ejhf.346)

Pellicori, P., Joseph, A. C., Zhang, J., Lukaschuk, E., Sherwi, N., Bourantas, C. V., Loh, H., Clark, A. L., Cleland, J. G.F. (2015) The relationship of QRS morphology with cardiac structure and function in patients with heart failure. Clinical Research in Cardiology, 104, pp. 935-945. (doi: 10.1007/s00392-015-0861-0)

Inglis, S. C., Clark, R. A., Dierckx, R., Prieto-Merino, D., Cleland, J. G.F. (2015) Structured telephone support or non-invasive telemonitoring for patients with heart failure. Cochrane Database of Systematic Reviews, 2015, (doi: 10.1002/14651858.CD007228.pub3)

Deng, L., Blanco Lopez, F. J., Stevens, H., Lu, R., Caudrillier, A., McBride, M., McClure, J. D., Grant, J., Thomas, M., Frid, M., Stenmark, K., White, K., Seto, A. G., Morrell, N. W., Bradshaw, A. C., MacLean, M. R., Baker, A. H. (2015) MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circulation Research, 117, pp. 870-883. (doi: 10.1161/CIRCRESAHA.115.306806)

Farag, M., Mabote, T., Shoaib, A., Zhang, J., Nabhan, A. F., Clark, A. L., Cleland, J. G. (2015) Hydralazine and nitrates alone or combined for the management of chronic heart failure: a systematic review. International Journal of Cardiology, 196, pp. 61-69. (doi: 10.1016/j.ijcard.2015.05.160)

Mareev, Y., Cleland, J. G.F. (2015) Should β-blockers be used in patients with heart failure and atrial fibrillation? Clinical Therapeutics, 37, pp. 2215-2224. (doi: 10.1016/j.clinthera.2015.08.017)

Shadman, R., Poole, J. E., Dardas, T. F., Mozaffarian, D., Cleland, J. G.F., Swedberg, K., Maggioni, A. P., Anand, I. S., Carson, P. E., Miller, A. B., Levy, W. C. (2015) A novel method to predict the proportional risk of sudden cardiac death in heart failure: derivation of the Seattle Proportional Risk Model. Heart Rhythm, 12, pp. 2069-2077. (doi: 10.1016/j.hrthm.2015.06.039)

Patel, R., Jeemon, P., Stevens, K., Mccallum, L., Hastie, C., Schneider, A., Jardine, A., Mark, P., Padmanabhan, S. (2015) Association between serum phosphate and calcium, long-term blood pressure, and mortality in treated hypertensive adults. Journal of Hypertension, 33, pp. 2046-2053. (doi: 10.1097/hjh.0000000000000659)

Butcher, C., Mareev, Y., Markides, V., Mason, M., Wong, T., Cleland, J.G.F. (2015) Cardiac resynchronization therapy update: evolving indications, expanding benefit? Current Cardiology Reports, 17, (doi: 10.1007/s11886-015-0641-5)

Akehurst, C., Small, H., Sharafetdinova, L., Forrest, R., Beattie, W., Brown, C. E., Robinson, S. W., McClure, J. D., Work, L. M., Carty, D. M., McBride, M. W., Freeman, D. J., Delles, C. (2015) Differential expression of microRNA-206 and its target genes in pre-eclampsia. Journal of Hypertension, 33, pp. 2068-2074. (doi: 10.1097/HJH.0000000000000656)

Frankenstein, L., Fröhlich, H., Cleland, J. G.F. (2015) Multidisciplinary approach for patients hospitalized with heart failure. Revista Española de Cardiología (English Edition), 68, pp. 885-891. (doi: 10.1016/j.rec.2015.05.008)

Cleland, J. G.F., Freemantle, N. (2015) QRS morphology as a predictor of the response to cardiac resynchronisation therapy: fact or fashion? Heart, 101, pp. 1441-1443. (doi: 10.1136/heartjnl-2015-307553)

Fisher, M., Petrie, M., Ambery, P., Donaldson, J., McMurray, J. J.V., Ye, J. (2015) Cardiovascular safety of albiglutide in the Harmony programme: a meta-analysis. Lancet Diabetes and Endocrinology, 3, pp. 697-703. (doi: 10.1016/s2213-8587(15)00233-8)

Damy, T., Hobkirk, J., Walters, M., Ciobanu, A., Rigby, A. S., Kallvikbacka-Bennett, A., Guellich, A., Dubois-Randé, J.-L., Hittinger, L., Clark, A. L., Cleland, J. G.F. (2015) Development of a human model for the study of effects of hypoxia, exercise, and sildenafil on cardiac and vascular function in chronic heart failure. Journal of Cardiovascular Pharmacology, 66, pp. 229-238. (doi: 10.1097/FJC.0000000000000262)

Dierckx, R., Cleland, J. G.F., Pellicori, P., Zhang, J., Goode, K., Putzu, P., Boyalla, V., Clark, A. L. (2015) If home telemonitoring reduces mortality in heart failure, is this just due to better guideline-based treatment? Journal of Telemedicine and Telecare, 21, pp. 331-339. (doi: 10.1177/1357633X15574947)

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Modern anticancer drugs improve cancer survival. However, this is associated with cardiovascular toxicities, the mechanisms of which often remain poorly defined and therefore cardiovascular preventative or treatment strategies are not optimal. We aim to minimise the competing risks of cardiovascular disease in patients with cancer.

Scope of research

Our pre-clinical studies provide mechanistic insights into cancer therapy-related cardiovascular toxicity. Our clinical trials and longitudinal cohort studies aim to inform better prediction, prevention and treatment of potential or established cancer therapy-related cardiovascular toxicity. We leverage large datasets to obtain epidemiologic insights.

The clinical research basis comes via a dedicated cardiovascular-oncology service. This is the only specialist service of its kind in Scotland and based at the Beatson West of Scotland Cancer Centre (BWoSCC), the busiest cancer centre in the UK in terms of clinical activity and patient numbers as well as being the second-largest cancer centre in the UK). This is the nucleus for clinical-academic collaboration and a major source for research participant recruitment.

The theme is a component of the strategic objectives of a British Heart Foundation (BHF) Centre of Excellence Award and is well supported by further specific research grants.

Membership and collaboration

The theme supports clinical and non-clinical PhD and post-doctoral fellows. Collaboration is wide within SCMH (including nephrology, hypertension, heart failure, data science) and elsewhere in the University of Glasgow (including School of Cancer Sciences and School of Infection and Inflammation, Paul O’Gorman Leukaemia Research Centre and School of Biodiversity, One Health & Veterinary Medicine). The Cardio-Nephro-Oncology (CaNOn) group brings together representatives of all of these groups and spans pre-clinical science, clinical trials and data science. We collaborate widely both within the UK and internationally.

Selected Cardio-oncology projects

  • Biomarker and PET imaging characterisation of inflammatory atheroma in patients receiving immunotherapy and angiogenesis inhibitors (BioCAPRI).
  • Biomarker and imaging characterisation of BRAF and MEK inhibitor-induced cardiovascular toxicity: prospective study in patients with cancer (BioCOBRA).
  • Investigating the long-term cardiac sequelae of trastuzumab therapy using cardiac MRI and comprehensive clinical phenotyping.
  • Markers and mediators of angiogenesis inhibitor-induced vascular and myocardial toxicity: prospective study in patients with cancer.
  • Cardiac CARE: A multicentre prospective randomised open-label blinded end-point controlled trial of high-sensitivity cardiac troponin I-guided combination angiotensin receptor blockade and beta blocker therapy to prevent cardiac toxicity in breast cancer patients receiving anthracycline adjuvant therapy.
  • Improving Cardiovascular Safety Assessment, Definition and Reporting in Oncology Clinical Trials: Providing cardiovascular clarity for a new era of cancer therapeutics.
  • Characterising risk factors and pathways for heart failure in patients with cancer: epidemiological insights via Safe Haven dataset.
  • Treatment of renal cancer and the impact on kidney function over time: Insights from national data.
  • Cardio-Oncology Research in Veterinary Medicine: Anti-VEGF tyrosine kinase inhibitors and cardiac remodelling in dogs treated for cancer.
  • Extended use of induced pluripotent stem cells in cardiotoxicity screening for systemic anti-cancer therapies.