Arrhythmias

Our work aims to understand the underlying mechanisms of cardiac arrhythmias so that we can develop novel therapeutic strategies and effective prediction tools for patients at risk of sudden arrhythmic death.

Staff

Publications

2024

Gök, C., Fuller, W. (2024) Rise of palmitoylation: a new trick to tune NCX1 activity. Biochimica et Biophysica Acta: Molecular Cell Research, 1871, (doi: 10.1016/j.bbamcr.2024.119719)

Chung, Y. J., Hoare, Z., Baark, F., Yu, C. S., Guo, J., Fuller, W., Southworth, R., Katschinski, D. M., Murphy, M. P., Eykyn, T. R., Shattock, M. J. (2024) Elevated Na is a dynamic and reversible modulator of mitochondrial metabolism in the heart. Nature Communications, 15, (doi: 10.1038/s41467-024-48474-z)

Sin, Y. Y., Cameron, R. T., Schepers, M., MacLeod, R., Wright, T. A., Paes, D., van den Hove, D., Willems, E., Vanmierlo, T., Prickaerts, J., Blair, C. M., Baillie, G. S. (2024) Beta-amyloid interacts with and activates the longform phosphodiesterase PDE4D5 in neuronal cells to reduce cAMP availability. FEBS Letters, (doi: 10.1002/1873-3468.14902)

Curtain, J. P., Talebi, A., McIntosh, A., McConnachie, A., O’Donnell, J., Welsh, P., Osmanska, J., Lee, M. M.Y., Sonecki, P., Akl, T., Seo, J., Gopinathan, V., Hurwitz, J., Thiagarajan, S., Pettit, S., Kalra, P. R., Patel, R. K., Mark, P. B., Lang, N. N., McMurray, J. J.V., Petrie, M. C., Gardner, R. S., Jhund, P. (2024) Measuring congestion with a non-invasive monitoring device in heart failure and haemodialysis: CONGEST-HF. European Journal of Heart Failure,

Richardson, S. H., Mackenzie, J., Thekkethil, N., Feng, L., Lee, J., Berry, C., Hill, N., Luo, X., Gao, H. (2024) Cardiac perfusion coupled with a structured coronary network tree. Computer Methods in Applied Mechanics and Engineering,

Butler, J. et al. (2024) Empagliflozin after acute myocardial infarction. New England Journal of Medicine, 390, pp. 1455-1466. (doi: 10.1056/NEJMoa2314051)

Cooke, S. F., Wright, T. A., Sin, Y. Y., Ling, J., Kyurkchieva, E., Phanthaphol, N., McSkimming, T., Herbert, K., Rebus, S., Biankin, A. V., Chang, D. K., Baillie, G. S., Blair, C. M. (2024) Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC. Scientific Reports, 14, (doi: 10.1038/s41598-024-59451-3)

Kosiborod, M. N. et al. (2024) Semaglutide in patients with obesity-related heart failure and type 2 diabetes. New England Journal of Medicine, 390, pp. 1394-1407. (doi: 10.1056/NEJMoa2313917)

Lang, N., Rankin, S., Elyan, B., Jones, R., Venugopal, B., Mark, P. B., Lees, J., Petrie, M., Lang, N. (2024) Cardiovascular eligibility criteria and adverse event reporting in combined immune checkpoint and VEGF inhibitors trials. JACC: CardioOncology, 6, pp. 267-279. (doi: 10.1016/j.jaccao.2023.12.010)

Glen, C., Morrow, A., Roditi, G., Hopkins, T., Macpherson, I., Stewart, P., Petrie, M. C., Berry, C., Epstein, F., Lang, N. N., Mangion, K. (2024) Cardiovascular sequalae of trastuzumab and anthracycline in long-term survivors of breast cancer. Heart, 110, pp. 650-656. (doi: 10.1136/heartjnl-2023-323437)

Carberry, J., Petrie, M. C., Lee, M. M.Y., Brooksbank, K., Campbell, R. T., Good, R., Jhund, P. S., Kellman, P., Lang, N. N., Mangion, K., Mark, P. B., McConnachie, A., McMurray, J. J.V., Meyer, B., Orchard, V., Shaukat, A., Watkins, S., Welsh, P., Sattar, N., Berry, C., Docherty, K. F. (2024) Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS-MI): rationale and design. ESC Heart Failure,

Hernandez, A. F. et al. (2024) Effect of empagliflozin on heart failure outcomes after acute myocardial infarction: insights from the EMPACT-MI trial. Circulation, (doi: 10.1161/circulationaha.124.069217)

Collet, C. et al. (2024) A systematic approach to the evaluation of the coronary microcirculation using bolus thermodilution: CATH CMD. Journal of the Society for Cardiovascular Angiography and Interventions, (doi: 10.1016/j.jscai.2024.101934)

Sattar, N., Butler, J., Lee, M. M.Y., Harrington, J., Sharma, A., Zannad, F., Filippatos, G., Verma, S., Januzzi, J. L., Ferreira, J. P., Pocock, S. J., Pfarr, E., Ofstad, A. P., Brueckmann, M., Packer, M., Anker, S. D. (2024) Body mass index and cardiorenal outcomes in the EMPEROR-Preserved trial: principal findings and meta-analysis with the DELIVER trial. European Journal of Heart Failure, (doi: 10.1002/ejhf.3221)

Udell, J. A. et al. (2024) Left ventricular function, congestion, and effect of empagliflozin on heart failure risk after myocardial infarction. Journal of the American College of Cardiology, (doi: 10.1016/j.jacc.2024.03.405)

Jackson, A. M., Goland, S., Farhan, H. A., Yaseen, I. F., Prameswari, H. S., Böhm, M., Jhund, P. S., Maggioni, A. P., van der Meer, P., Sliwa, K., Bauersachs, J., Petrie, M. C. (2024) A novel score to predict left ventricular recovery in peripartum cardiomyopathy derived from the ESC EORP Peripartum Cardiomyopathy Registry. European Heart Journal, 45, pp. 1430-1439. (doi: 10.1093/eurheartj/ehad888)

Yang, Y., Husmeier, D., Gao, H., Berry, C., Carrick, D., Radjenovic, A. (2024) Automatic detection of myocardial ischaemia using generalisable spatio-temporal hierarchical Bayesian modelling of DCE-MRI. Computerized Medical Imaging and Graphics, 113, (doi: 10.1016/j.compmedimag.2024.102333)

Docherty, K. F., McMurray, J. J.V., Kalra, P., Cleland, J. G.F., Lang, N. N., Petrie, M. C., Robertson, M., Ford, I. (2024) Intravenous iron and SGLT2 inhibitors in iron-deficient patients with heart failure and reduced ejection fraction. ESC Heart Failure, (doi: 10.1002/ehf2.14742)

Savarese, G., Lindberg, F., Christodorescu, R. M., Ferrini, M., Kumler, T., Toutoutzas, K., Dattilo, G., Bayes-Genis, A., Moura, B., Amir, O., Petrie, M. C., Seferovic, P., Chioncel, O., Metra, M., Coats, A. J.S., Rosano, G. M.C. (2024) Physician perceptions, attitudes, and strategies towards implementing guideline-directed medical therapy in heart failure with reduced ejection fraction. A survey of the Heart Failure Association of the ESC and the ESC Council for Cardiology Practice. European Journal of Heart Failure, (doi: 10.1002/ejhf.3214)

Bai, M., Gallen, E., Memarzadeh, S., Howie, J., GAO, X., Kuo, C.-W. S., Brown, E., Swingler, S., Wilson, S. J., Shattock, M. J., France, D. J., Fuller, W. (2024) Targeted degradation of zDHHC-PATs decreases substrate S -palmitoylation. PLoS ONE, 19, (doi: 10.1371/journal.pone.0299665)

Knigge, P., Lundberg, S., Strange, J. E., Malik, M. E., Nouhravesh, N., Wagner, A. K., Gislason, G., Fosbøl, E. L., Carlson, N., Zahir, D., Andersson, C., Butt, J. H., Jhund, P., Petrie, M. C., McMurray, J. J.V., Køber, L., Schou, M. (2024) Temporal trends in the initiation of dialysis among patients with heart failure with or without diabetes: a nationwide study from 2002 to 2016. Journal of the American Heart Association, 13, (doi: 10.1161/JAHA.123.032539)

Ashford, F., Kuo, C.-W., Dunning, E., Brown, E., Calagan, S., Jayasinghe, I., Henderson, C., Fuller, W., Wypijewski, K. (2024) Cysteine post-translational modifications regulate protein interactions of caveolin-3. FASEB Journal, 38, (doi: 10.1096/fj.202201497RR)

Campbell, P., Rutten, F. H., Lee, M. M. Y., Hawkins, N. M., Petrie, M. C. (2024) Heart failure with preserved ejection fraction: Everything the clinician needs to know. Lancet, 403, pp. 1083-1092. (doi: 10.1016/S0140-6736(23)02756-3)

Astrauskaite, G., Mohanan, S., Williamson, L., Boland, E., Huethorst, E., Kinegawa, R., Smith, G., Muellenbroich, C. (2024) Remote Focusing for 2-photon Microscopy to Follow Action Potential Propagation Transmurally in Acute Rabbit Cardiac Slices. (doi: 10.1117/12.3002956)

Ang, D. T.Y., Carrick, D., Kamdar, A., Sykes, R., McGeoch, R. J., Collison, D., McConnachie, A., Berry, C. (2024) Intracoronary adenosine derived coronary flow reserve and index of microvascular resistance. Circulation: Cardiovascular Interventions,

Freeman, M., Huethorst, E., Boland, E., Dunne, M., Burton, F., Denning, C., Myles, R., Smith, G. (2024) A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit. American Journal of Physiology: Heart and Circulatory Physiology, 326, pp. H735--H751. (doi: 10.1152/ajpheart.00657.2023)

Sliwa, K., van der Meer, P., Viljoen, C., Jackson, A. M., Petrie, M. C., Mebazaa, A., Hilfiker-Kleiner, D., Maggioni, A. P., Laroche, C., Regitz-Zagrosek, V., Tavazzi, L., Roos-Hesselink, J. W., Hamdan, R., Frogoudaki, A., Ibrahim, B., Farhan, H. A. F., Mbakwem, A., Seferovic, P., Böhm, M., Pieske, B., Johnson, M. R., Bauersachs, J. (2024) Socio-economic factors determine maternal and neonatal outcomes in women with peripartum cardiomyopathy: a study of the ESC EORP PPCM registry. International Journal of Cardiology, 398, (doi: 10.1016/j.ijcard.2023.131596)

Deo, S. V., Al-Kindi, S., Motairek, I., McAllister, D., Shah, A. S.V., Elgudin, Y. E., Gorodeski, E. Z., Virani, S., Petrie, M. C., Rajagopalan, S., Sattar, N. (2024) Impact of residential social deprivation on prediction of heart failure in patients with type 2 diabetes: External validation and recalibration of the WATCH-DM score using real world data. Circulation: Cardiovascular Quality and Outcomes, 17, pp. 267-276. (doi: 10.1161/circoutcomes.123.010166)

Bosserdt, M. et al. (2024) Age and computed tomography and invasive coronary angiography in stable chest pain: a prespecified secondary analysis of the discharge randomized clinical trial. JAMA Cardiology, 9, pp. 346-356. (doi: 10.1001/jamacardio.2024.0001)

Rudd, A. E., Horgan, G., Khan, H., Gamble, D. T., McGowan, J., Sood, A., McGeoch, R., Irving, J., Watt, J., Leslie, S. J., Petrie, M., Lang, C., Mills, N. L., Newby, D. E., Dawson, D. K. (2024) Cardiovascular and noncardiovascular prescribing and mortality after takotsubo comparison with myocardial infarction and general population. JACC: Advances, 3, (doi: 10.1016/j.jacadv.2023.100797)

Osmanska, J., Petrie, M. C., Campbell, R. T. (2024) Reply: subcutaneous furosemide patch: heart failure decongestion "from the comfort of your home" European Heart Journal: Cardiovascular Pharmacotherapy, (doi: 10.1093/ehjcvp/pvae015)

Mellbin, L. G., Bhatt, D. L., David, J.-P., Ekström, K., Petrie, M. C., Rasmussen, S., Vilsbøll, T. (2024) Semaglutide and cardiovascular outcomes by baseline HbA1c in diabetes: the SUSTAIN 6 and PIONEER 6 trials. European Heart Journal, 45, pp. 1371-1374. (doi: 10.1093/eurheartj/ehae028)

Morrow, A. J. et al. (2024) Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization. Communications Medicine, 4, (doi: 10.1038/s43856-024-00455-5)

Kelham, M., Vyas, R., Rameseshan, R., Rathod, K., de Winter, R.J., de Winter, R.W., Bendz, B., Thiele, H., Hirlekar, G., Morici, N., Myat, A., Michalis, L., Sanchis, J., Kunadian, V., Berry, C., Mathur, A., Jones, D. (2024) 100.03 Routine Invasive Versus Conservative Management of Non-ST Elevation Acute Coronary Syndromes in Patients With Previous Coronary Artery Bypass Grafting: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. (doi: 10.1016/j.jcin.2024.01.082)

Sykes, R., Hanna, R., Berry, C. (2024) Prognostic importance of fractional flow reserve and left ventricular systolic dysfunction after percutaneous coronary intervention. JACC: Asia, (doi: 10.1016/j.jacasi.2023.12.002)

UK HFpEF Collaborative Group, , , (2024) Rationale and design of the United Kingdom Heart Failure with Preserved Ejection Fraction Registry. Heart, 110, pp. 359-365. (doi: 10.1136/heartjnl-2023-323049)

Black, N., Bradley, J., Lewis, G., Lagan, J., Orsborne, C., Soltani, F., Farrant, J. P., McDonagh, T., Schmitt, M., Cavalcante, J. L., Ugander, M., Butler, J., Petrie, M. C., Miller, C. A., Schelbert, E. B. (2024) Development and validation of imaging-free myocardial fibrosis prediction models, association with outcomes, and sample size estimation for phase 3 trials. medRxiv, (doi: 10.1101/2024.02.07.24302443)

Goldie, F. C., Lee, M. M. Y., Coats, C. J., Nordin, S. (2024) Advances in multi-modality imaging in hypertrophic cardiomyopathy. Journal of Clinical Medicine, 13, (doi: 10.3390/jcm13030842)

Butt, J. H., McDowell, K., Kondo, T., Desai, A. S., Lefkowitz, M. P., Packer, M., Petrie, M. C., Pfeffer, M. A., Rouleau, J. L., Vaduganathan, M., Zile, M. R., Jhund, P. S., Køber, L., Solomon, S., McMurray, J. J.V. (2024) Heart failure with preserved ejection fraction, red cell distribution width, and sacubitril/valsartan. ESC Heart Failure, 11, pp. 65-77. (doi: 10.1002/ehf2.14558)

Omerovic, E., Petrie, M., Redfors, B., Fremes, S., Murphy, G., Marquis-Gravel, G., Lansky, A., Velazquez, E., Perera, D., Reid, C., Smith, J., van der Meer, P., Lipsic, E., Juni, P., McMurray, J., Bauersachs, J., Køber, L., Rouleau, J. L., Doenst, T. (2024) Pragmatic randomized controlled trials: strengthening the concept through a robust international collaborative network: PRIME-9-pragmatic research and innovation through multinational experimentation. Trials, 25, (doi: 10.1186/s13063-024-07935-y)

Petrie, M. C., Rouleau, J. L., Claggett, B., Jering, K., van der Meer, P., Køber, L., Miao, Z. M., Lewis, E., Granger, C., De Pasqulae, C. G., Mann, D., Steg, P. G., Maggioni, A., Amir, O., Lefkowitz, M., Braunwald, E., Solomon, S. D., McMurray, J. J. V., Pfeffer, M. A. (2024) Pulmonary congestion and left ventricular dysfunction after myocardial infarction: insights from the PARADISE-MI trial. Circulation, 149, pp. 335-38. (doi: 10.1161/CIRCULATIONAHA.123.066163)

Howie, J., Tulloch, L. B., Brown, E., Reilly, L., Ashford, F. B., Kennedy, J., Wypijewski, K. J., Aughton, K. L., Mak, J. K.C., Shattock, M. J., Fraser, N. J., Fuller, W. (2024) Glutathione-dependent depalmitoylation of phospholemman by peroxiredoxin 6. Cell Reports, 43, (doi: 10.1016/j.celrep.2024.113679)

Kosiborod, M. N., Verma, S., Borlaug, B. A., Butler, J., Davies, M. J., Jon Jensen, T., Rasmussen, S., Erlang Marstrand, P., Petrie, M. C., Shah, S. J., Ito, H., Schou, M., Melenovský, V., Abhayaratna, W., Kitzman, D. W., STEP-HFpEF Trial Committees and Investigators, (2024) Effects of semaglutide on symptoms, function, and quality of life in patients with heart failure with preserved ejection fraction and obesity: a prespecified analysis of the STEP-HFpEF trial. Circulation, 149, pp. 204-216. (doi: 10.1161/circulationaha.123.067505)

Sidik, N. P., Stanley, B., Sykes, R., Morrow, A. J., Bradley, C. P., Mcdermott, M., Ford, T., Roditi, G., Hargreaves, A., Stobo, D., Adams, J., Byrne, J., Mahrous, A., Young, R., Carrick, D., McGeoch, R., Corcoran, D., Lang, N. N., Heggie, R., Wu, O., McEntegart, M. B., McConnachie, A., Berry, C. (2024) Invasive endotyping in patients with angina and no obstructive coronary artery disease: a randomized controlled trial. Circulation, 149, pp. 7-23. (doi: 10.1161/CIRCULATIONAHA.123.064751)

Osmanska, J., Brooksbank, K., Docherty, K. F., Robertson, S., Wetherall, K., McConnachie, A., Hu, J., Gardner, R. S., Clark, A. L., Squire, I. B., Kalra, P. R., Jhund, P. S., Muntendam, P., McMurray, J. J.V., Petrie, M. C., Campbell, R. T. (2024) A novel, small-volume subcutaneous furosemide formulation delivered by an abdominal patch infusor device in patients with heart failure: results of two phase I studies. European Heart Journal: Cardiovascular Pharmacotherapy, 10, pp. 35-44. (doi: 10.1093/ehjcvp/pvad073)

Lee, M. M.Y., Kondo, T., Campbell, R. T., Petrie, M. C., Sattar, N., Solomon, S. D., Vaduganathan, M., Jhund, P. S., McMurray, J. J.V. (2024) Effects of Renin-Angiotensin system blockers on outcomes from COVID-19: a systematic review and meta-analysis of randomised controlled trials. European Heart Journal: Cardiovascular Pharmacotherapy, 10, pp. 68-80. (doi: 10.1093/ehjcvp/pvad067)

Chivardi, C. et al. (2024) Percutaneous revascularization for ischemic left ventricular dysfunction: Cost-effectiveness analysis of the REVIVED-BCIS2 trial. Circulation: Cardiovascular Quality and Outcomes, 17, (doi: 10.1161/circoutcomes.123.010533)

2023

Lee, M. M.Y., Lean, M. E.J., Sattar, N., Petrie, M. C. (2023) Appetite and its regulation: Are there palatable interventions for heart failure? Current Heart Failure Reports, 21, pp. 1-4. (doi: 10.1007/s11897-023-00637-7)

Gulliver, C., Busiau, T., Byrne, A., Findlay, J. E., Hoffmann, R., Baillie, G. (2023) cAMP-phosphodiesterase 4D7 (PDE4D7) forms a cAMP signalosome complex with DHX9 and is implicated in prostate cancer progression. Molecular Oncology, (doi: 10.1002/1878-0261.13572)

Kosiborod, M. N., Borlaug, B. A., Petrie, M. C. (2023) Semaglutide and heart failure with preserved ejection fraction and obesity. Reply. New England Journal of Medicine, 389, pp. 2398-2399. (doi: 10.1056/NEJMc2312296)

Lee, M. M.Y., Masri, A. (2023) Correction to: Differentiating cardiac troponin levels during cardiac myosin inhibition or cardiac myosin activation treatments: drug effect or the canary in the coal mine? Current Heart Failure Reports, (doi: 10.1007/s11897-023-00639-5)

Connelly, P., Osmanska, J., Lee, M. M.Y., Delles, C., McEntegart, M. B., Byrne, J. (2023) A case report of myocardial infarction in a young transgender man with testosterone therapy? raising awareness on healthcare issues in the transgender community and a call for further research. European Heart Journal: Case Reports, 7, (doi: 10.1093/ehjcr/ytad562)

McErlane, J., McCall, P., Willder, J., Berry, C., Shelley, B. (2023) Cardiac biomarkers and right ventricular dysfunction are independently associated with one year mortality in patients with COVID-19 receiving mechanical ventilation: a prospective cohort study. CHEST Critical Care, 1, (doi: 10.1016/j.chstcc.2023.100015)

Lee, M. M. Y., Masri, A. (2023) Differentiating cardiac troponin levels during cardiac myosin inhibition or cardiac myosin activation treatments: drug effect or the canary in the coal mine? Current Heart Failure Reports, 20, pp. 504-518. (doi: 10.1007/s11897-023-00620-2)

Zahir Anjum, D., Strange, J. E., Fosbøl, E., Garred, C. H., Malik, M. E., Andersson, C., Jhund, P. S., McMurray, J. J.V., Petrie, M. C., Kober, L., Schou, M. (2023) Initiation of medical therapy for heart failure patients according to kidney function: a Danish nationwide study. Clinical Epidemiology, 15, pp. 855-866. (doi: 10.2147/clep.s412787)

Berry, C. et al. (2023) Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study. Heart and Mind, 7, pp. 235-245. (doi: 10.4103/hm.HM-D-23-00037)

McDowell, K., Adamson, C., Jackson, C., Campbell, R., Welsh, P., Petrie, M. C., McMurray, J. J.V., Jhund, P., Herring, N. (2023) Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes. European Journal of Heart Failure, (doi: 10.1002/ejhf.3085)

Ray, R., Ford, I., Cleland, J. G.F., Graham, F., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Critoph, C., Kalra, P. A., Lane, R. E., Ludman, A., Pellicori, P., Petrie, M. C., Robertson, M., Seed, A., Squire, I., Kalra, P. R. (2023) The impact of ferric derisomaltose on cardiovascular and non-cardiovascular events in patients with anemia, iron deficiency and heart failure with reduced ejection fraction. Journal of Cardiac Failure, (doi: 10.1016/j.cardfail.2023.10.006)

Martin, T. P., MacDonald, E. A., Bradley, A., Watson, H., Saxena, P., Rog-Zielinska, E. A., Raheem, A., Fisher, S., Elbassioni, A. A. M., Almuzaini, O., Booth, C., Campbell, M., Riddell, A., Herzyk, P., Blyth, K., Nixon, C., Zentilin, L., Berry, C., Braun, T., Giacca, M., McBride, M. W., Nicklin, S. R., Cameron, E. R., Loughrey, C. (2023) Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. Cardiovascular Research, 119, pp. 2663–2671-2663–2671. (doi: 10.1093/cvr/cvad107)

Fuller, W., Mejías, R. (2023) Editorial: Protein lipidation in health and disease. Frontiers in Physiology, 14, (doi: 10.3389/fphys.2023.1317031)

Selli, A. L., Ghasemi, M., Watters, T., Burton, F., Smith, G., Dietrichs, E. S. (2023) Proarrhythmic changes in human cardiomyocytes during hypothermia by milrinone and isoprenaline, but not levosimendan: an experimental in vitro study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 31, (doi: 10.1186/s13049-023-01134-5)

Glen, C., Adam, S., McDowell, K., Waterston, A., Tan, Y. Y., Petrie, M. C., Coats, C. J., Lang, N. N. (2023) Cardiotoxicity of BRAF/MEK inhibitors: a longitudinal study incorporating contemporary definitions and risk scores. JACC: CardioOncology, 5, pp. 628-637. (doi: 10.1016/j.jaccao.2023.04.004)

Jackson, A., Bauersachs, J., Petrie, M. C., van der Meer, P., Laroche, C., Farhan, H. A., Frogoudaki, A., Ibrahim, B., Fouad, D. A., Damasceno, A., Karaye, K., Goland, S., Maggioni, A. P., Briton, O., Sliwa, K. (2023) Outcomes at one year in women with peripartum cardiomyopathy: findings from the ESC EORP PPCM Registry. European Journal of Heart Failure, (doi: 10.1002/ejhf.3055)

Jackson, A. M., Macartney, M., Brooksbank, K., Brown, C., Dawson, D., Francis, M., Japp, A., Lennie, V., Leslie, S. J., Martin, T., Neary, P., Venakatasubramanian, S., Vickers, D., Weir, R. A., McMurray, J. J.V., Jhund, P. S., Petrie, M. C. (2023) A 20-year population study of peripartum cardiomyopathy. European Heart Journal, (doi: 10.1093/eurheartj/ehad626)

Giommi, A., Gurgel, A. R. B., Smith, G. L., Workman, A. J. (2023) Does the small conductance Ca2+-activated K+ current ISK flow under physiological conditions in rabbit and human atrial isolated cardiomyocytes? Journal of Molecular and Cellular Cardiology, 183, pp. 70-80. (doi: 10.1016/j.yjmcc.2023.09.002)

Malik, M. E., Butt, J. H., Strange, J. E., Falkentoft, A. C., Jensen, J., Andersson, C., Zahir, D., Fosbøl, E., Petrie, M. C., Sattar, N., McMurray, J. J.V., Køber, L., Schou, M. (2023) Initiation of SGLT2 inhibitors and GLP-1 receptor agonists according to level of frailty in people with type 2 diabetes and cardiovascular disease in Denmark: a cross-sectional, nationwide study. Lancet Healthy Longevity, 4, pp. e552-e560. (doi: 10.1016/S2666-7568(23)00164-2)

Gulliver, C., Baillie, G. S., Hoffmann, R. (2023) Reduced PDE4D7 in prostate cancer correlates with genomic downregulation within the upstream PDE4D coding region. Future Science OA, 9, (doi: 10.2144/fsoa-2023-0064)

Parsons, E. C., Baillie, G. S., Hoffmann, R. (2023) Revisiting the roles of cAMP signalling in the progression of prostate cancer. Biochemical Journal, 480, pp. 1599-1614. (doi: 10.1042/BCJ20230297)

Gulliver, C., Huss, S., Semjonow, A., Baillie, G. S., Hoffmann, R. (2023) Loss of PDE4D7 expression promotes androgen independence, neuroendocrine differentiation, and alterations in DNA repair: implications for therapeutic strategies. British Journal of Cancer, (doi: 10.1038/s41416-023-02417-5)

Perera, D. et al. (2023) Arrhythmia and death following percutaneous revascularization in ischemic left ventricular dysfunction: Prespecified analyses from the REVIVED-BCIS2 trial. Circulation: Heart Failure, 148, pp. 862-871. (doi: 10.1161/circulationaha.123.065300)

Wright, T. A., Gemmell, A. O., Tejeda, G. S., Blair, C. M., Baillie, G. S. (2023) Cancer: phosphodiesterase type 4C (PDE4C), the forgotten subfamily as a therapeutic target. International Journal of Biochemistry and Cell Biology, 162, (doi: 10.1016/j.biocel.2023.106453)

Brennan, A. C., Campbell, R. T., Lee, M. M.Y. (2023) Influenza vaccination: a simple, safe, and effective treatment for patients with ischaemic heart disease and heart failure. European Journal of Heart Failure, 25, pp. 1693-1695. (doi: 10.1002/ejhf.2993)

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Fuller, W. (2023) zDHHC9 and the control of natriuretic peptide secretion by the heart. JACC: Basic to Translational Science, 8, pp. 543-545. (doi: 10.1016/j.jacbts.2023.02.013)

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Desai, A. S., Petrie, M. C. (2023) Centrally adjudicated heart failure outcomes are needed in clinical trials. JACC: Heart Failure, 11, pp. 418-421. (doi: 10.1016/j.jchf.2023.01.028)

Dobbin, S. J.H., Shen, L., Petrie, M. C., Packer, M., Solomon, S. D., McMurray, J. J.V., Lang, N. N., Jhund, P. S. (2023) Characteristics and outcomes of patients with a history of cancer recruited to heart failure trials. European Journal of Heart Failure, 25, pp. 488-496. (doi: 10.1002/ejhf.2818)

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Pathak, S., Lai, F. Y., Miksza, J., Petrie, M. C., Roman, M., Murray, S., Dearling, J., Perera, D., Murphy, G. J. (2023) Surgical or percutaneous coronary revascularization for heart failure: an in silico model using routinely collected health data to emulate a clinical trial. European Heart Journal, 44, pp. 351-364. (doi: 10.1093/eurheartj/ehac670)

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Petrie, M. C., Jhund, P. S., Connolly, E., Mark, P. B., MacDonald, M. R., Robertson, M., Anker, S. D., Bhandari, S., Farrington, K., Kalra, P. A., Wheeler, D. C., Tomson, C. R.V., Ford, I., McMurray, J. J.V., Macdougall, I. C. (2023) High-dose intravenous iron reduces myocardial infarction in patients on haemodialysis. Cardiovascular Research, 119, pp. 213-220. (doi: 10.1093/cvr/cvab317)

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2022

Collet, C., Collison, D., Mizukami, T., McCartney, P., Sonck, J., Ford, T., Munhoz, D., Berry, C., De Bruyne, B., Oldroyd, K. (2022) Differential improvement in angina and health-related quality of life after PCI in focal and diffuse coronary artery disease. JACC: Cardiovascular Interventions, 15, pp. 2506-2518. (doi: 10.1016/j.jcin.2022.09.048)

Kalra, P. R., Cleland, J. G.F., Petrie, M. C., Thomson, E. A., Kalra, P. A., Squire, I. B., Ahmed, F. Z., Al-Mohammad, A., Cowburn, P. J., Foley, P. W.X., Graham, F. J., Japp, A. G., Lane, R. E., Lang, N. N., Ludman, A. J., Macdougall, I. C., Pellicori, P., Ray, R., Robertson, M., Seed, A., Ford, I. (2022) Intravenous ferric derisomaltose in patients with heart failure and iron deficiency in the UK (IRONMAN): an investigator-initiated, prospective, randomised, open-label, blinded-endpoint trial. Lancet, 400, pp. 2199-2209. (doi: 10.1016/S0140-6736(22)02083-9)

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Saxena, P., Myles, R. C., Smith, G. L., Workman, A. J. (2022) Adrenoceptor sub-type involvement in Ca2+ current stimulation by noradrenaline in human and rabbit atrial myocytes. Pflügers Archiv European Journal of Physiology, 474, pp. 1311-1321. (doi: 10.1007/s00424-022-02746-z)

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Bradley, C., Berry, C. (2022) Retinal microvascular function: a tractable biomarker of cardiovascular risk? Cardiovascular Research, 118, pp. 3169-3170. (doi: 10.1093/cvr/cvac170)

Cervilla-Martínez, J. F., Rodríguez-Gotor, J. J., Wypijewski, K. J., Fontán-Lozano, Á., Wang, T., Santamaría, E., Fuller, W., Mejías, R. (2022) Altered cortical palmitoylation induces widespread molecular disturbances in Parkinson's disease. International Journal of Molecular Sciences, 23, (doi: 10.3390/ijms232214018)

McErlane, J., McCall, P., Willder, J., Berry, C., Shelley, B. (2022) Right ventricular free wall longitudinal strain is independently associated with mortality in mechanically ventilated patients with COVID-19. Annals of Intensive Care, 12, (doi: 10.1186/s13613-022-01077-7)

Tromp, J., Bauer, D., Claggett, B. L., Frost, M., Iversen, M. B., Prasad, N., Petrie, M. C., Larson, M. G., Ezekowitz, J. A., Solomon, S. D. (2022) A formal validation of a deep learning-based automated workflow for the interpretation of the echocardiogram. Nature Communications, 13, (doi: 10.1038/s41467-022-34245-1)

Paterson, C., Hinterberg, M. A., Morrow, A. J., Sykes, R., Mangion, K., Welsh, P., McConnachie, A., Sattar, N., Berry, C., Williams, S. A. (2022) Utility of a Proteomic Surrogate for Cardiovascular Outcomes to Predict and Monitor COVID-19 Induced Myocarditis. (doi: 10.1161/circ.146.suppl_1.12132)

Kondo, T., Abdul-Rahim, A. H., Talebi, A., Abraham, W. T., Desai, A. S., Dickstein, K., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F. A., Packer, M., Petrie, M., Ponikowski, P., Rouleau, J. L., Sabatine, M. S., Swedberg, K., Zile, M. R., Solomon, S. D., Jhund, P. S., McMurray, J. J.V. (2022) Predicting stroke in heart failure and reduced ejection fraction without atrial fibrillation. European Heart Journal, 43, pp. 4469-4479. (doi: 10.1093/eurheartj/ehac487)

Yang, Y., Gao, H., Berry, C., Carrick, D., Radjenovic, A., Husmeier, D. (2022) Classification of myocardial blood flow based on dynamic contrast-enhanced magnetic resonance imaging using hierarchical Bayesian models. Journal of the Royal Statistical Society: Series C (Applied Statistics), 71, pp. 1085-1115. (doi: 10.1111/rssc.12568)

Morris, P. D., Al-Lamee, R. K., Berry, C., on behalf of the BCIS Research and Development Committee, (2022) Coronary physiological assessment in the catheter laboratory: haemodynamics, clinical assessment and future perspectives. Heart, 108, pp. 1737-1746. (doi: 10.1136/heartjnl-2020-318743)

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Ferreira, V. M., Berry, C. (2022) The health economics of ischemia with nonobstructive coronary arteries. JACC: Cardiovascular Imaging, 14, pp. 1380-1383. (doi: 10.1016/j.jcmg.2021.03.017)

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Crea, F., Badimon, L., Berry, C., De Caterina, R., Elliott, P. M., Hatala, R., Libby, P., Linde, C., Tybjaerg-Hansen on behalf of the EHJ Editorial Board, A. (2022) The European Heart Journal: fulfilling the mission. European Heart Journal, 43, pp. 2181-2184. (doi: 10.1093/eurheartj/ehac171)

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2021

Chung, Y. J., Park, K. C., Tokar, S., Eykyn, T. R., Fuller, W., Pavlovic, D., Swietach, P., Shattock, M. J. (2021) Off-target effects of SGLT2 blockers: empagliflozin does not inhibit Na+/H+ exchanger-1 or lower [Na+]i in the heart. Cardiovascular Research, 117, pp. 2794-2806. (doi: 10.1093/cvr/cvaa323)

Collison, D., Didagelos, M., Aetesam-Ur-Rahman, M., Copt, S., McDade, R., McCartney, P., Ford, T. J., McClure, J., Lindsay, M., Shaukat, A., Rocchiccioli, P., Brogan, R., Watkins, S., McEntegart, M., Good, R., Robertson, K., O’Boyle, P., Davie, A., Khan, A., Hood, S., Eteiba, H., Berry, C., Oldroyd, K. G. (2021) Post-stenting fractional flow reserve vs coronary angiography for optimization of percutaneous coronary intervention (TARGET-FFR) European Heart Journal, 42, pp. 4656-4668. (doi: 10.1093/eurheartj/ehab449)

Chung, Y. J., Park, K. C., Tokar, S., Eykyn, T. R., Fuller, W., Pavlovic, D., Swietach, P., Shattock, M. J. (2021) SGLT2 inhibitors and the cardiac Na+/H+ exchanger-1: the plot thickens. Cardiovascular Research, 117, pp. 2702-2704. (doi: 10.1093/cvr/cvab184)

Butt, J. H., Adamson, C., Docherty, K. F., de Boer, R. A., Petrie, M. C., Inzucchi, S. E., Kosiborod, M. N., Maria Langkilde, A., Lindholm, D., Martinez, F. A., Bengtsson, O., Schou, M., O’Meara, E., Ponikowski, P., Sabatine, M. S., Sjöstrand, M., Solomon, S. D., Jhund, P. S., McMurray, J. J.V., Køber, L. (2021) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to N-terminal pro-B-type natriuretic peptide: insights from the DAPA-HF trial. Circulation: Heart Failure, 14, (doi: 10.1161/CIRCHEARTFAILURE.121.008837)

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Rush, C. J., Berry, C., Oldroyd, K. G., Rocchiccioli, J. P., Lindsay, M. M., Touyz, R. M., Murphy, C. L., Ford, T. J., Sidik, N., McEntegart, M. B., Lang, N. N., Jhund, P. S., Campbell, R. T., McMurray, J. J.V., Petrie, M. C. (2021) Prevalence of coronary artery disease and coronary microvascular dysfunction in patients with heart failure with preserved ejection fraction. JAMA Cardiology, 6, pp. 1130-1143. (doi: 10.1001/jamacardio.2021.1825)

Anderson, J. J., Ho, F. K., Niedzwiedz, C. L., Katikireddi, V., Celis-Morales, C., Iliodromiti, S., Welsh, P., Pellicori, P., Demou, E., Hastie, C. E., Lyall, D. M., Gray, S. R., Forbes, J. F., Gill, J. M.R., Mackay, D. F., Berry, C., Cleland, J. G.F., Sattar, N., Pell, J. P. (2021) Remote history of VTE is associated with severe COVID-19 in middle and older age: UK Biobank cohort study. Journal of Thrombosis and Haemostasis, 19, pp. 2533-2538. (doi: 10.1111/jth.15452)

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MacDonald, E. A., Quinn, T. A. (2021) What keeps us ticking? Sinoatrial node mechano-sensitivity: the grandfather clock of cardiac rhythm. Biophysical Reviews, 13, pp. 707-716. (doi: 10.1007/s12551-021-00831-8)

Curtain, J. P., Docherty, K. F., Jhund, P. S., Petrie, M. C., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Martinez, F., Ponikowski, P., Sabatine, M. S., Bengtsson, O., Langkilde, A. M., Sjöstrand, M., Solomon, S. D., McMurray, J. J.V. (2021) Effect of dapagliflozin on ventricular arrhythmias, resuscitated cardiac arrest, or sudden death in DAPA-HF. European Heart Journal, 42, pp. 3727-3738. (doi: 10.1093/eurheartj/ehab560)

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Kerr, M., Dennis, K.M.J.H., Carr, C.A., Fuller, W., Berridge, G., Rohling, S., Aitken, C.L., Lopez, C., Fischer, R., Miller, J.J., Clarke, K., Tyler, D.J., Heather, L.C. (2021) Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischaemia. FASEB Journal, 35, (doi: 10.1096/fj.202100394R)

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Lee, M. M.Y., McMurray, J. J.V., Jhund, P. S., Petrie, M. C., Sattar, N. (2021) Response by Lee et al to letter regarding article, "Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)" Circulation, 144, pp. e40. (doi: 10.1161/CIRCULATIONAHA.121.055067)

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Simpson, J., Jackson, C. E., Haig, C., Jhund, P. S., Tomaszewski, M., Gardner, R. S., Tsorlalis, Y., Petrie, M. C., McMurray, J. J.V., Squire, I. B., Gupta, P. (2021) Adherence to prescribed medications in patients with heart failure – insights from liquid chromatography-tandem mass spectrometry-based urine analysis. European Heart Journal: Cardiovascular Pharmacotherapy, 7, pp. 296-301. (doi: 10.1093/ehjcvp/pvaa071)

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Gök, C., Main, A., Gao, X., Kerekes, Z., Plain, F., Kuo, C.-W., Robertson, A. D., Fraser, N. J., Fuller, W. (2021) Insights into the molecular basis of the palmitoylation and depalmitoylation of NCX1. Cell Calcium, 97, (doi: 10.1016/j.ceca.2021.102408)

Morgan, D. C., Morris, C., Mahindra, A., Blair, C. M., Tejeda, G., Herbert, I., Turnbull, M. L., Lieber, G., Willett, B. J., Logan, N., Smith, B., Tobin, A. B., Bhella, D., Baillie, G. S., Jamieson, A. G. (2021) Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalisation. Peptide Science, 113, (doi: 10.1002/pep2.24217)

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Anand, A., Lee, K. K., Chapman, A. R., Ferry, A. V., Adamson, P. D., Strachan, F. E., Berry, C., Findlay, I., Cruikshank, A., Reid, A., Collinson, P. O., Apple, F. S., McAllister, D., Maguire, D., Fox, K. A.A., Newby, D. E., Tuck, C., Harkess, R., Keerie, C., Weir, C. J., Parker, R. A., Gray, A., Shah, A. S.V., Mills, N. (2021) High-sensitivity cardiac troponin on presentation to rule out myocardial infarction: a stepped-wedge cluster randomized controlled trial. Circulation, 143, pp. 2214-2224. (doi: 10.1161/CIRCULATIONAHA.120.052380)

Butt, J. H., Docherty, K. F., Petrie, M. C., Schou, M., Kosiborod, M. N., O’Meara, E., Katova, T., Ljungman, C. E.A., Diez, M., Ogunniyi, M. O., Langkilde, A. M., Sjöstrand, M., Lindholm, D., Bengtsson, O., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Jhund, P. S., McMurray, J. J.V., Køber, L. (2021) Efficacy and safety of dapagliflozin in men and women with heart failure with reduced ejection fraction: results from the DAPA-HF trial. JAMA Cardiology, 6, pp. 678-689. (doi: 10.1001/jamacardio.2021.0379)

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Maznyczka, A. M., Carrick, D., Oldroyd, K. G., James-Rae, G., McCartney, P., Greenwood, J. P., Good, R., McEntegart, M., Eteiba, H., Lindsay, M., Cotton, J. M., Petrie, M. C., Berry, C. (2021) Thermodilution-derived temperature recovery time, a novel predictor of microvascular reperfusion and prognosis after myocardial infarction. EuroIntervention, 17, pp. 220-228. (doi: 10.4244/EIJ-D-19-00904)

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Lee, M. M.Y., Ghouri, N., McGuire, D. K., Rutter, M. K., Sattar, N. (2021) Meta-analyses of results from randomized outcome trials comparing cardiovascular effects of SGLT2i and GLP-1RA in Asian vs. White patients with and without type 2 diabetes. Diabetes Care, 44, pp. 1236-1241. (doi: 10.2337/dc20-3007)

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Mooney, L., Goodyear, C. S., Chandra, T., Kirschner, K., Copland, M., Petrie, M. C., Lang, N. N. (2021) Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure. Clinical Science, 135, pp. 991-1007. (doi: 10.1042/CS20200306)

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Sliwa, K. et al. (2021) Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European Journal of Heart Failure, 23, pp. 527-540. (doi: 10.1002/ejhf.2133)

Scott, M., Blondel-Tepaz, E., Leverve, M., Sokrat, B., Paradis, J., Kosic, M., Saha, K., Auffray, C., Lima-Fernandes, E., Zamborlini, A., Poupon, A., Gaboury, L., Findlay, J., Baillie, G., Enslen, H., Bouvier, M., Angers, S., Marullo, S. (2021) The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signalling axis. Oncogene, 40, pp. 2243-2257. (doi: 10.1038/s41388-021-01704-w)

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Briscoe, M., Sykes, R., Krystofiak, T., Peck, O., Mangion, K., Berry, C. (2021) Clinical significance of coronavirus disease 2019 in hospitalized patients with myocardial injury. Clinical Cardiology, 44, pp. 332-339. (doi: 10.1002/clc.23530)

Sykes, R. A., Mohamed, M. O., Kwok, C. S., Mamas, M. A., Berry, C. (2021) Percutaneous coronary intervention and 30-day unplanned readmission with chest pain in the United States (nationwide readmissions database) Clinical Cardiology, 44, pp. 291-306. (doi: 10.1002/clc.23543)

Doherty, D. J., Sykes, R., Mangion, K., Berry, C. (2021) Predictors of microvascular reperfusion after myocardial infarction. Current Cardiology Reports, 23, (doi: 10.1007/s11886-021-01442-1)

Tomasoni, D., Petrie, M. C., Adamo, M., Metra, M. (2021) Renin-angiotensin-aldosterone inhibitors and COVID-19: nearing the end of a media-fuelled controversy. European Journal of Heart Failure, 23, pp. 486-488. (doi: 10.1002/ejhf.2098)

Hortigon-Vinagre, M.P., Zamora, V., Burton, F. L., Smith, G. L. (2021) The use of voltage sensitive dye di-4-ANEPPS and video-based contractility measurements to assess drug effects on excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes. Journal of Cardiovascular Pharmacology, 77, pp. 280-290. (doi: 10.1097/FJC.0000000000000937)

Lee, M. M.Y. et al. (2021) Invasive versus medically managed acute coronary syndromes with prior bypass (CABG-ACS): insights into the registry versus randomised trial populations. Open Heart, 8, (doi: 10.1136/openhrt-2020-001453)

Ehteshami-Afshar, S., Mooney, L., Dewan, P., Desai, A. S., Lang, N. N., Lefkowitz, M. P., Petrie, M. C., Rizkala, A. R., Rouleau, J. L., Solomon, S. D., Swedberg, K., Shi, V. C., Zile, M. R., Packer, M., McMurray, J. J.V., Jhund, P. S., Hawkins, N. M. (2021) Clinical characteristics and outcomes of patients with heart failure with reduced ejection fraction and chronic obstructive pulmonary disease: insights from PARADIGM-HF. Journal of the American Heart Association, 10, (doi: 10.1161/JAHA.120.019238)

Lee, M. M.Y. et al. (2021) Effect of empagliflozin on left ventricular volumes in patients with type 2 diabetes, or prediabetes, and heart failure with reduced ejection fraction (SUGAR-DM-HF) Circulation, 143, pp. 516-525. (doi: 10.1161/CIRCULATIONAHA.120.052186)

Petrie, M. C., Lee, M. M., Lang, N. N. (2021) EMPEROR-REDUCED reigns while EMPERIAL whimpers. European Heart Journal, 42, pp. 711-714. (doi: 10.1093/eurheartj/ehaa965)

Li, W., Gao, H., Mangion, K., Berry, C., Luo, X. (2021) Apparent growth tensor of left ventricular post myocardial infarction – in human first natural history study. Computers in Biology and Medicine, 129, (doi: 10.1016/j.compbiomed.2020.104168)

Maznyczka, A. M., McCartney, P., Duklas, P., McEntegart, M., Oldroyd, K., Greenwood, J., Muir, D., Chowdhary, S., Gershlick, A. H., Eteiba, H., Cotton, J., Wragg, A., Curzen, N., Tait, R., Macfarlane, P., Welsh, P., Sattar, N., Petrie, M., Ford, I., Fox, K., McConnachie, A., Berry, C. (2021) Effect of coronary flow on intracoronary alteplase: a prespecified analysis from a randomised trial. Heart, 107, pp. 299-312. (doi: 10.1136/heartjnl-2020-317828)

Docherty, K. F., Campbell, R. T., Brooksbank, K. J.M., Godeseth, R. L., Forsyth, P., McConnachie, A., Roditi, G., Stanley, B., Welsh, P., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2021) Rationale and methods of a randomized trial evaluating the effect of neprilysin inhibition on left ventricular remodelling. ESC Heart Failure, 8, pp. 129-138. (doi: 10.1002/ehf2.13137)

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Baillie, G. S., Gulliver, C., Hoffmann, R. (2021) The enigmatic helicase DHX9 and its association with the hallmarks of cancer. Future Science OA, 7, (doi: 10.2144/fsoa-2020-0140)

Robertson-Gray, O., Fuller, W. (2021) The role of protein S-acylation in cardiac function. Clinical Laboratory International, Feb, pp. 10-13.

Main, A., Robertson-Gray, O., Fuller, W. (2021) Cyclophilin D palmitoylation and permeability transition: a new twist in the tale of myocardial ischaemia-reperfusion injury. Cardiovascular Research, 117, pp. 15-17. (doi: 10.1093/cvr/cvaa149)

Corcoran, D., Radjenovic, A., Mordi, I., Nazir, S. A., Wilson, S. J., Hinder, M., Yates, D. P., Machineni, S., Alcantara, J., Prescott, M. F., Gugliotta, B., Pang, Y., Tzemos, N., Semple, S. I., Newby, D. E., McCann, G. P., Squire, I., Berry, C. (2021) Vascular effects of serelaxin in patients with stable coronary artery disease: a randomized placebo-controlled trial. Cardiovascular Research, 117, pp. 320-329. (doi: 10.1093/cvr/cvz345)

Dobbin, S. J.H., Petrie, M. C., Myles, R. C., Touyz, R. M., Lang, N. N. (2021) Cardiotoxic effects of angiogenesis inhibitors. Clinical Science, 135, pp. 71-100. (doi: 10.1042/CS20200305)

Willder, J. M., McCall, P., Messow, C.-M., Gillies, M., Berry, C., Shelley, B. (2021) Study protocol for COVID-RV: a multicentre prospective observational cohort study of right ventricular dysfunction in ventilated patients with COVID-19. BMJ Open, 11, (doi: 10.1136/bmjopen-2020-042098)

Burton, R. F., Burton, F. L. (2021) When is sitting height a better measure of adult body size than total height, and why? The contrasting examples of body mass, waist circumference and lung volume. American Journal of Human Biology, 33, (doi: 10.1002/ajhb.23433)

Jacobs, M., Benovoy, M., Chang, L.-C., Corcoran, D., Berry, C., Arai, A. E., Hsu, L.-Y. (2021) Automated segmental analysis of fully quantitative myocardial blood flow maps by first-pass perfusion cardiovascular magnetic resonance. IEEE Access, 9, pp. 52796-52811. (doi: 10.1109/ACCESS.2021.3070320)

Kamdar, A., Sykes, R., Morrow, A., Mangion, K., Berry, C. (2021) Cardiovascular outcomes of glucose lowering therapy in chronic kidney disease patients: a systematic review with meta-analysis. Reviews in Cardiovascular Medicine, 22, pp. 1479-1490. (doi: 10.31083/j.rcm2204152)

Da Silva Costa, A., Mortensen, P., Hortigon-Vinagre, M. P., van der Heyden, M. A. G., Burton, F. L., Gao, H., Simitev, R. D., Smith, G. L. (2021) Electrophysiology of hiPSC-cardiomyocytes co-cultured with HEK cells expressing the inward rectifier channel. International Journal of Molecular Sciences, 22, (doi: 10.3390/ijms22126621)

Boguslavskyi, A., Tokar, S., Prysyazhna, O., Rudyk, O., Sanchez-Tatay, D., Lemmey, H. A.L., Dora, K. A., Garland, C. J., Warren, H. R., Doney, A., Palmer, C. N.A., Caulfield, M. J., Vlachaki Walker, J., Howie, J., Fuller, W., Shattock, M. J. (2021) Phospholemman phosphorylation regulates vascular tone, blood pressure and hypertension in mice and man. Circulation, 143, pp. 1123-1138. (doi: 10.1161/CIRCULATIONAHA.119.040557)

Sykes, R., Briscoe, M., Krystofiak, T., Peck, O., Mangion, K., Berry, C. (2021) Type 2 myocardial infarction and myocardial injury: eligibility for novel medical therapy to de-risk clinical trials. Open Heart, 8, (doi: 10.1136/openhrt-2021-001633)

Ang, D. T. Y., Berry, C. (2021) What an interventionalist needs to know about INOCA. Interventional Cardiology Review, 16, (doi: 10.15420/icr.2021.16)

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2020

Rossitto, G., Mary, S., McAllister, C., Neves, K. B., Haddow, L., Rocchiccioli, J. P., Lang, N. N., Murphy, C. L., Touyz, R. M., Petrie, M. C., Delles, C. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76, pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022)

Lee, M. (2020) Studies of Empagliflozin and its Cardiovascular, Renal and Metabolic Effects in Patients With Diabetes Mellitus (or Prediabetes) and Heart Failure: a Randomized Controlled Trial (SUGAR-DM-HF) (doi: 10.1161/CIR.0000000000000940)

Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, 116, pp. 2185-2196. (doi: 10.1093/cvr/cvaa209)

Mangion, K., Loughrey, C., Auger, D. A., McComb, C., Lee, M. M., Corcoran, D., McEntegart, M., Davie, A., Good, R., Lindsay, M., Eteiba, H., Rocchiccioli, J. P., Watkins, S., Hood, S., Shaukat, A., Haig, C., Epstein, F. H., Berry, C. (2020) Displacement encoding with stimulated echoes enables the identification of infarct transmurality early postmyocardial infarction. Journal of Magnetic Resonance Imaging, 52, pp. 1722-1731. (doi: 10.1002/jmri.27295)

Ferreira, J. P., Docherty, K. F., Stienen, S., Jhund, P. S., Claggett, B. L., Solomon, S. D., Petrie, M. C., Gregsone, J., Pocock, S. L., Zannad, F., McMurray, J. (2020) Estimating the lifetime benefits of treatments for heart failure. JACC: Heart Failure, 8, pp. 984-995. (doi: 10.1016/j.jchf.2020.08.004)

Main, A., Fuller, W., Baillie, G. S. (2020) Post-translational regulation of cardiac myosin binding protein-C: a graphical review. Cellular Signalling, 76, (doi: 10.1016/j.cellsig.2020.109788)

Gök, C., Fuller, W. (2020) Topical review: shedding light on molecular and cellular consequences of NCX1 palmitoylation. Cellular Signalling, 76, (doi: 10.1016/j.cellsig.2020.109791)

Mackenzie, I. S. et al. (2020) Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial. Lancet, 396, pp. 1745-1757. (doi: 10.1016/S0140-6736(20)32234-0)

Ho, F. K., Celis-Morales, C. A., Gray, S. R., Katikireddi, S. V., Niedzwiedz, C. L., Hastie, C., Ferguson, L. D., Berry, C., Mackay, D. F., Gill, J. M.R., Pell, J. P., Sattar, N., Welsh, P. (2020) Modifiable and non-modifiable risk factors for COVID-19, and comparison to risk factors for influenza and pneumonia: results from a UK Biobank prospective cohort study. BMJ Open, 10, (doi: 10.1136/bmjopen-2020-040402)

Briscoe, M., Sykes, R. A., Krysztofiak, T., Peck, O. H., Mangion, K., Berry, C. (2020) Clinical Significance of Coronavirus Disease 2019 in Hospitalized Patients With Myocardial Injury. (doi: 10.1161/circ.142.suppl_3.15932)

Briscoe, M., Sykes, R. A., Krysztofiak, T., Mangion, K., Peck, O. H., Berry, C. (2020) Clinical Significance of Troponin Elevation in a Contemporary Hospitalized Population: Endotypes, Morbidity and In-hospital Mortality. (doi: 10.1161/circ.142.suppl_3.14870)

Dietrichs, E. S., McGlynn, K., Allan, A., Connolly, A., Bishop, M., Burton, F., Kettlewell, S., Myles, R., Tveita, T., Smith, G. L. (2020) Moderate but not severe hypothermia causes pro-arrhythmic changes in cardiac electrophysiology. Cardiovascular Research, 116, pp. 2081-2090. (doi: 10.1093/cvr/cvz309)

McEwan, P., Darlington, O., McMurray, J. J.V., Jhund, P. S., Docherty, K. F., Böhm, M., Petrie, M. C., Bergenheim, K., Qin, L. (2020) Cost-effectiveness of dapagliflozin as a treatment for heart failure with reduced ejection fraction: a multinational health-economic analysis of DAPA-HF. European Journal of Heart Failure, 22, pp. 2147-2156. (doi: 10.1002/ejhf.1978)

Ferreira, J. P., Dewan, P., Jhund, P., Lorenzo-Almorós, A., Duarte, K., Petrie, M., Carson, P. E., McKelvie, R., Komajda, M., Zile, M., Zannad, F., McMurray, J. J.V. (2020) Covariate adjusted reanalysis of the I-Preserve trial. Clinical Research in Cardiology, 109, pp. 1358-1365. (doi: 10.1007/s00392-020-01632-x)

Seferović, P. M. et al. (2020) Heart Failure Association of the European Society of Cardiology update on sodium glucose co‐transporter‐2 inhibitors in heart failure (an update on the Sodium–glucose co‐transporter 2 inhibitors in heart failure: beyond glycaemic control. The position paper of the Heart Failure Association of the European Society of Cardiology) European Journal of Heart Failure, 22, pp. 1984-1986. (doi: 10.1002/ejhf.2026)

McCartney, P. J. et al. (2020) Low-dose intracoronary alteplase during primary percutaneous coronary intervention in patients with acute myocardial infarction: the T-TIME three-arm RCT. Efficacy and Mechanism Evaluation, 7, (doi: 10.3310/eme07050)

Morrow, A. J. et al. (2020) Rationale and design of the Medical Research Council precision medicine with Zibotentan in microvascular angina (PRIZE) trial. American Heart Journal, 229, pp. 70-80. (doi: 10.1016/j.ahj.2020.07.007)

Dewan, P., Jackson, A., Jhund, P. S., Shen, L., Ferreira, J. P., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Køber, L., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2020) The prevalence and importance of frailty in heart failure with reduced ejection fraction – an analysis of PARADIGM-HF and ATMOSPHERE. European Journal of Heart Failure, 22, pp. 2123-2133. (doi: 10.1002/ejhf.1832)

Kunadian, V., Chieffo, A., Camici, P. G., Berry, C., Escaned, J., Maas, A. H. E. M., Prescott, E., Karam, N., Appelman, Y., Fraccaro, C., Louise Buchanan, G., Manzo-Silberman, S., Al-Lamee, R., Regar, E., Lansky, A., Abbott, J. D., Badimon, L., Duncker, D. J., Mehran, R., Capodanno, D., Baumbach, A. (2020) An EAPCI expert consensus document on ischaemia with non-obstructive coronary arteries in collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology & Microcirculation endorsed by Coronary Vasomotor Disorders International Study Group. European Heart Journal, 41, pp. 3504-3520. (doi: 10.1093/eurheartj/ehaa503)

Lang, N. N., Dobbin, S. J.H., Petrie, M. C. (2020) Vericiguat in worsening heart failure – agonising over, or celebrating, agonism. Cardiovascular Research, 116, pp. e152-e155. (doi: 10.1093/cvr/cvaa247)

Butt, J. H., Fosbøl, E. L., Gerds, T. A., Andersson, C., McMurray, J. J.V., Petrie, M. C., Gustafsson, F., Madelaire, C., Kristensen, S. L., Gislason, G. H., Torp-Pedersen, C., Køber, L., Schou, M. (2020) Readmission and death in patients admitted with new-onset versus worsening of chronic heart failure: insights from a nationwide cohort. European Journal of Heart Failure, 22, pp. 1777-1785. (doi: 10.1002/ejhf.1800)

Ford, T. J., Corcoran, D., Padmanabhan, S., Aman, A., Rocchiccioli, P., Good, R., McEntegart, M., Maguire, J. J., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., Yii, E., Sattar, N., Hsu, L.-Y., Arai, A. E., Oldroyd, K. G., Touyz, R. M., Davenport, A. P., Berry, C. (2020) Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction. European Heart Journal, 41, pp. 3239-3252. (doi: 10.1093/eurheartj/ehz915)

Sattar, N., Ho, F. K., Gill, J. M.R., Ghouri, N., Gray, S. R., Celis-Morales, C. A., Katikireddi, S. V., Berry, C., Pell, J. P., McMurray, J. J.V., Welsh, P. (2020) BMI and future risk for COVID-19 infection and death across sex, age and ethnicity: preliminary findings from UK biobank. Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 14, pp. 1149-1151. (doi: 10.1016/j.dsx.2020.06.060)

Seferović, P. M. et al. (2020) Sodium–glucose co‐transporter 2 inhibitors in heart failure: beyond glycaemic control. A position paper of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 22, pp. 1495-1503. (doi: 10.1002/ejhf.1954)

Aksentijević, D., Karlstaedt, A., Basalay, M. V., O’Brien, B. A., Sanchez-Tatay, D., Eminaga, S., Thakker, A., Tennant, D. A., Fuller, W., Eykyn, T. R., Taegtmeyer, H., Shattock, M. J. (2020) Intracellular sodium elevation reprograms cardiac metabolism. Nature Communications, 11, (doi: 10.1038/s41467-020-18160-x)

Ford, T. J., Ong, P., Sechtem, U., Beltrame, J., Camici, P. G., Crea, F., Kaski, J.-C., Bairey Merz, C. N., Pepine, C. J., Shimokawa, H., Berry, C. (2020) Assessment of vascular dysfunction in patients without obstructive coronary artery disease: why, how and when. JACC: Cardiovascular Interventions, 13, pp. 1847-1864. (doi: 10.1016/j.jcin.2020.05.052)

Rossitto, G., Mary, S., Chen, J. Y., Bodder, P., Chew, K. S., Neves, K. B., Alves, R. L., Montezano, A. C., Welsh, P., Petrie, M. C., Graham, D., Touyz, R. M., Delles, C. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, (doi: 10.1038/s41467-020-17820-2)

McClure, J. D., Ramsay, J. C., Berry, C. (2020) Pooled analysis of bleeding and major adverse cardiovascular events in clinical trials of time-constrained dual-antiplatelet therapy after percutaneous coronary intervention. Journal of the American Heart Association, 9, (doi: 10.1161/JAHA.120.017109)

Guzik, T. J., Mohiddin, S. A., Dimarco, A., Patel, V., Savvatis, K., Marelli-Berg, F. M., Madhur, M. S., Tomaszewksi, M., Maffia, P., D'Acquisto, F., Nicklin, S. A., Marian, A. J., Nosalski, R., Murray, E. C., Guzik, B., Berry, C., Touyz, R. M., Kreutz, R., Wang, D. W., Bhella, D., Sagliocco, O., Crea, F., Thomson, E. C., McInnes, I. B. (2020) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research, 116, pp. 1666-1687. (doi: 10.1093/cvr/cvaa106)

Zou, Z.-G., Rios, F. J., Neves, K. B., Alves-Lopes, R., Ling, J., Baillie, G. S., Gao, X., Fuller, W., Camargo, L. L., Gudermann, T., Chubanov, V., Montezano, A. C., Touyz, R. M. (2020) Epidermal growth factor signaling through transient receptor potential melastatin 7 cation channel regulates vascular smooth muscle cell function. Clinical Science, 134, pp. 2019-2035. (doi: 10.1042/CS20200827)

Plain, F., Howie, J., Kennedy, J., Brown, E., Shattock, M. J., Fraser, N. J., Fuller, W. (2020) Control of protein palmitoylation by regulating substrate recruitment to a zDHHC-protein acyltransferase. Communications Biology, 3, (doi: 10.1038/s42003-020-01145-3)

MacDonald, E. A., Madl, J., Greiner, J., Ramadan, A. F., Wells, S. M., Torrente, A. G., Kohl, P., Rog-Zielinska, E. A., Quinn, T. A. (2020) Sinoatrial node structure, mechanics, electrophysiology and the chronotropic response to stretch in rabbit and mouse. Frontiers in Physiology, 11, (doi: 10.3389/fphys.2020.00809)

Fong, L. C. W., Ford, T. J., da Costa, B. R., Jüni, P., Berry, C. (2020) Bias and loss to follow-up in cardiovascular randomized trials: a systematic review. Journal of the American Heart Association, 9, (doi: 10.1161/JAHA.119.015361)

Bulluck, H., Carberry, J., Carrick, D., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Mahrous, A., Ford, I., Oldroyd, K. G., Berry, C. (2020) Redefining adverse and reverse left ventricular remodeling by cardiovascular magnetic resonance following ST-segment elevation myocardial infarction and their implications on long-term prognosis. Circulation: Cardiovascular Imaging, 13, (doi: 10.1161/CIRCIMAGING.119.009937)

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Williams, J. J.L., Baillie, G. S., Palmer, T. M. (2020) Investigation of Novel Cavin-1/Suppressor of Cytokine Signaling 3 (SOCS3) Interactions by Coimmunoprecipitation, Peptide Pull-Down, and Peptide Array Overlay Approaches. Springer

Al-Hussaini, A., Abdelaty, A. M.S.E.K., Gulsin, G. S., Arnold, J. R., Garcia-Guimaraes, M., Premawardhana, D., Budgeon, C., Wood, A., Natarajan, N., Mangion, K., Rakhit, R., Hoole, S. P., Johnson, T. W., Berry, C., Hudson, I., Gershlick, A. H., Ladwiniec, A., Kovac, J., Squire, I., Samani, N. J., Plein, S., McCann, G. P., Adlam, D. (2020) Chronic infarct size after spontaneous coronary artery dissection: implications for pathophysiology and clinical management. European Heart Journal, 41, pp. 2197-2205. (doi: 10.1093/eurheartj/ehz895)

Gök, C., Plain, F., Robertson, A., Howie, J., Baillie, G. S., Fraser, N. J., Fuller, W. (2020) Dynamic palmitoylation of the sodium-calcium exchanger modulates its structure, affinity for lipid ordered domains, and inhibition by XIP. Cell Reports, 31, (doi: 10.1016/j.celrep.2020.107697)

Sidik, N., McDermott, M., McEntegart, M. B., Berry, C. (2020) Chest pain without obstructive coronary artery disease: a case series report. European Heart Journal: Case Reports, 4, pp. 1-6. (doi: 10.1093/ehjcr/ytaa060)

Collison, D., McClure, J. D., Berry, C., Oldroyd, K. G. (2020) A randomized controlled trial of a physiology‐guided percutaneous coronary intervention optimization strategy: rationale and design of the TARGET FFR study. Clinical Cardiology, 43, pp. 414-422. (doi: 10.1002/clc.23342)

Maznyczka, A. M., Oldroyd, K. G., Greenwood, J. P., McCartney, P. J., Cotton, J., Lindsay, M., McEntegart, M., Rocchiccioli, J. P., Good, R., Robertson, K., Eteiba, H., Watkins, S., Shaukat, A., Petrie, C. J., Murphy, A., Petrie, M. C., Berry, C. (2020) Comparative significance of invasive measures of microvascular injury in acute myocardial infarction. Circulation: Cardiovascular Interventions, 13, (doi: 10.1161/CIRCINTERVENTIONS.119.008505)

Hawkins, N. M., Osmanska, J., Petrie, M. C. (2020) Implantable cardioverter-defibrillators and survival - the fine line between efficacy concerns and ageism. European Journal of Heart Failure, 22, pp. 868-870. (doi: 10.1002/ejhf.1803)

Hennigan, B., Berry, C., Collison, D., Corcoran, D., Eteiba, H., Good, R., McEntegart, M., Watkins, S., McClure, J., Mangion, K., Ford, T., Petrie, M. C., Hood, S., Rocchiccioli, P., Shaukat, A., Lindsay, M., Oldroyd, K. G. (2020) Percutaneous coronary intervention versus medical therapy in patients with angina and grey-zone fractional flow reserve values: a randomised clinical trial. Heart, 106, pp. 714-715. (doi: 10.1136/heartjnl-2019-316075)

Docherty, K. F., Ferreira, J. P., Sharma, A., Girerd, N., Gregson, J., Duarte, K., Petrie, M. C., Jhund, P. S., Dickstein, K., Pfeffer, M. A., Pitt, B., Rossignol, P., Zannad, F., McMurray, J. J.V. (2020) Predictors of sudden cardiac death in high-risk patients following a myocardial infarction. European Journal of Heart Failure, 22, pp. 848-855. (doi: 10.1002/ejhf.1694)

Li, W., Lazarus, A., Gao, H., Martinez De Azcona Naharro, A., Fontana, M., Hawkins, P., Biswas, S., Janiczek, R., Cox, J., Berry, C., Husmeier, D., Luo, X. (2020) Analysis of cardiac amyloidosis progression using model-based markers. Frontiers in Physiology, 11, (doi: 10.3389/fphys.2020.00324)

Ling, J., Blair, C. M., Baillie, G. S. (2020) Fibrin Breakdown Assay. Bio-Protocol, 10, (doi: 10.21769/BioProtoc.3585)

Petrie, M. C., et al. (2020) Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes. JAMA: Journal of the American Medical Association, 323, pp. 1353-1368. (doi: 10.1001/jama.2020.1906)

Dietrichs, E. S., Tveita, T., Myles, R., Smith, G. (2020) A novel ECG-biomarker for cardiac arrest during hypothermia. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 28, (doi: 10.1186/s13049-020-00721-0)

Blair, C. M., Ling, J., Baillie, G. S. (2020) Measuring cAMP specific phosphodiesterase activity: a two-step radioassay. Bio-Protocol, 10, (doi: 10.21769/BioProtoc.3581)

Jackson, A. M., Zhang, R., Findlay, I., Robertson, K., Lindsay, M., Morris, T., Forbes, B., Papworth, R., McConnachie, A., Mangion, K., Jhund, P. S., McCowan, C., Berry, C. (2020) Healthcare disparities for women hospitalised with myocardial infarction and angina. European Heart Journal: Quality of Care and Clinical Outcomes, 6, pp. 156-165. (doi: 10.1093/ehjqcco/qcz040)

Simpson, J., Jhund, P. S., Lund, L. H., Padmanabhan, S., Clagget, B. L., Shen, L., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Kober, L., Paker, M., Rouleau, J. L., Mueller-Velten, G., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2020) Prognostic models derived in PARADIGM-HF and validated in ATMOSPHERE and the Swedish Heart Failure Registry to predict mortality and morbidity in chronic heart failure. JAMA Cardiology, 5, pp. 432-441. (doi: 10.1001/jamacardio.2019.5850)

Mangion, K., Adamson, P. D., Williams, M. C., Hunter, A., Pawade, T., Shah, A. S.V., Lewis, S., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D., McAllister, D., Berry, C. (2020) Sex associations and computed tomography coronary angiography-guided management in patients with stable chest pain. European Heart Journal, 41, pp. 1337-1345. (doi: 10.1093/eurheartj/ehz903)

Berry, C., Duncker, D. J. (2020) Coronary microvascular disease: the next frontier for Cardiovascular Research. Cardiovascular Research, 116, pp. 737-740. (doi: 10.1093/cvr/cvaa035)

MacDonald, E. A., Rose, R. A., Quinn, T. A. (2020) Neurohumoral control of sinoatrial node activity and heart rate: insight from experimental models and findings from humans. Frontiers in Physiology, 11, (doi: 10.3389/fphys.2020.00170)

Ford, T. J., Berry, C. (2020) Angina: contemporary diagnosis and management. Heart, 106, pp. 387-398. (doi: 10.1136/heartjnl-2018-314661)

Lee, M. M.Y., Petrie, M. C., McMurray, J. J.V., Sattar, N. (2020) How do SGLT2 (sodium-glucose cotransporter 2) inhibitors and GLP-1 (glucagon-like peptide-1) receptor agonists reduce cardiovascular outcomes? Arteriosclerosis, Thrombosis, and Vascular Biology, 40, pp. 506-522. (doi: 10.1161/atvbaha.119.311904)

Sidik, N. P., McEntegart, M., Roditi, G., Ford, T. J., McDermott, M., Morrow, A., Byrne, J., Adams, J., Hargreaves, A., Oldroyd, K. G., Stobo, D., Wu, O., Messow, C.-M., McConnachie, A., Berry, C. (2020) Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Function and CT Coronary Angiogram (CorCTCA) study. American Heart Journal, 221, pp. 48-59. (doi: 10.1016/j.ahj.2019.11.015)

Fuller, W., Gök, C. (2020) Regulation of NCX1 by palmitoylation. Cell Calcium, 86, (doi: 10.1016/j.ceca.2019.102158)

Docherty, K. F., Shen, L., Castagno, D., Petrie, M. C., Abraham, W. T., Böhm, M., Desai, A. S., Dickstein, K., Køber, L. V., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Vazir, A., Zile, M. R., Jhund, P. S., McMurray, J. J.V. (2020) Relationship between heart rate and outcomes in patients in sinus rhythm or atrial fibrillation with heart failure and reduced ejection fraction. European Journal of Heart Failure, 22, pp. 528-538. (doi: 10.1002/ejhf.1682)

Lochhead, M. R., Brown, A. D., Kirlin, A. C., Chitayat, S., Munro, K., Findlay, J. E., Baillie, G. S., LeBrun, D. P., Langelaan, D. N., Smith, S. P. (2020) Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A. Journal of Biological Chemistry, 27, pp. 4303-4315. (doi: 10.1074/jbc.RA119.011078)

Serenelli, M., Jackson, A., Dewan, P., Jhund, P. S., Petrie, M. C., Rossignol, P., Campo, G., Pitt, B., Zannad, F., Ferreira, J. P., McMurray, J. J.V. (2020) Mineralocorticoid receptor antagonists, blood pressure, and outcomes in heart failure with reduced ejection fraction. JACC: Heart Failure, 8, pp. 188-198. (doi: 10.1016/j.jchf.2019.09.011)

Huethorst, E., Cutiongco, M. F.A., Campbell, F. A., Saeed, A., Love, R., Reynolds, P. M., Dalby, M. J., Gadegaard, N. (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12, (doi: 10.1088/1758-5090/ab5d3f)

Maznyczka, A. M., McCartney, P. J., Oldroyd, K. G., Lindsay, M., McEntegart, M., Eteiba, H., Rocchiccioli, P., Good, R., Shaukat, A., Robertson, K., Kodoth, V., Greenwood, J. P., Cotton, J. M., Hood, S., Watkins, S., Macfarlane, P. W., Kennedy, J., Tait, C., Welsh, P., Sattar, N., Collison, D., Gillespie, L., McConnachie, A., Berry, C. (2020) Effects of intracoronary alteplase on microvascular function in acute myocardial infarction. Journal of the American Heart Association, 9, (doi: 10.1161/JAHA.119.014066)

Morrow, A., Sidik, N., Berry, C. (2020) ISCHEMIA: new questions from a landmark trial. Cardiovascular Research, 116, pp. e23-e25. (doi: 10.1093/cvr/cvz343)

Rankin, A. J., Allwood-Spiers, S., Lee, M. M.Y., Zhu, L., Woodward, R., Kuehn, B., Radjenovic, A., Sattar, N., Roditi, G., Mark, P. B., Gillis, K. A. (2020) Comparing the interobserver reproducibility of different regions of interest on multi-parametric renal magnetic resonance imaging in healthy volunteers, patients with heart failure and renal transplant recipients. Magnetic Resonance Materials in Physics, Biology and Medicine, 33, pp. 103-112. (doi: 10.1007/s10334-019-00809-4)

Seferović, P. M. et al. (2020) European Society of Cardiology/Heart Failure Association position paper on the role and safety of new glucose‐lowering drugs in patients with heart failure. European Journal of Heart Failure, 22, pp. 196-213. (doi: 10.1002/ejhf.1673)

Maznyczka, A. M. et al. (2020) One-year outcomes after low-dose intracoronary alteplase during primary percutaneous coronary intervention. The T-TIME randomized trial. Circulation: Cardiovascular Interventions, 13, (doi: 10.1161/CIRCINTERVENTIONS.119.008855)

Ford, T. J., Khan, A., Docherty, K. F., Jackson, A., Morrow, A., Sidik, N., Rocchiccioli, P., Good, R., Eteiba, H., Watkins, S., Shaukat, A., Lindsay, M., Robertson, K., Petrie, M., Berry, C., Oldroyd, K., McEntegart, M. (2020) Sex differences in procedural and clinical outcomes following rotational atherectomy. Catheterization and Cardiovascular Interventions, 95, pp. 232-241. (doi: 10.1002/ccd.28373)

Fraser, N. J., Howie, J., Wypijewski, K. J., Fuller, W. (2020) Therapeutic targeting of protein S-acylation for the treatment of disease. Biochemical Society Transactions, 48, pp. 281-290. (doi: 10.1042/BST20190707)

Kosiborod, M. N., Jhund, P., Docherty, K. F., Diez, M., Petrie, M. C., Verma, S., Nicolau, J. C., Merkely, B., Kitakaze, M., DeMets, D. L., Inzucchi, S. E., Køeber, L., Martinez, F. A., Ponikowski, P., Sabatine, M. S., Solomon, S. D., Bengtsson, O., Lindholm, D., Niklasson, A., Sjöstrand, M., Langkilde, A. M., McMurray, J. J.V. (2020) Effects of dapagliflozin on symptoms, function and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial. Circulation, 141, pp. 90-99. (doi: 10.1161/CIRCULATIONAHA.119.044138)

Martinez, F. A., Serenelli, M., Nicolau, J. C., Petrie, M. C., Chiang, C.-E., Tereshchenko, S., Solomon, S. D., Inzucchi, S. E., Køber, L., Kosiborod, M. N., Ponikowski, P., Sabatine, M. S., DeMets, D. L., Dutkiewicz-Piasecka, M., Bengtsson, O., Sjöstrand, M., Langkilde, A. M., Jhund, P., McMurray, J. J.V. (2020) Efficacy and safety of dapagliflozin in heart failure with reduced ejection fraction according to age: insights from DAPA-HF. Circulation, 141, pp. 100-111. (doi: 10.1161/CIRCULATIONAHA.119.044133)

Ford, T. J., Stanley, B., Sidik, N., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., Yii, E., McCartney, P., Corcoran, D., Collison, D., Rush, C., Sattar, N., McConnachie, A., Touyz, R. M., Oldroyd, K. G., Berry, C. (2020) 1-year outcomes of angina management guided by invasive coronary function testing (CorMicA) JACC: Cardiovascular Interventions, 13, pp. 33-45. (doi: 10.1016/j.jcin.2019.11.001)

Tejeda, G. S., Whiteley, E. L., Deeb, T. Z., Bürli, R. W., Moss, S. J., Sheridan, E., Brandon, N. J., Baillie, G. S. (2020) Chorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzyme. Proceedings of the National Academy of Sciences of the United States of America, 117, pp. 677-688. (doi: 10.1073/pnas.1916398117)

Chapman, A. R., Adamson, P. D., Shah, A. S.V., Anand, A., Strachan, F. E., Ferry, A. V., Lee, K. K., Berry, C., Findlay, I., Cruikshank, A., Reid, A., Gray, A., Collinson, P. O., Apple, F., McAllister, D., McAllister, D. A., Maguire, D., Fox, K. A.A., Vallejos, C. A., Keerie, C., Weir, C. J., Newby, D. E., Mills, N. L. (2020) High-sensitivity cardiac troponin and the universal definition of myocardial infarction. Circulation, 141, pp. 161-171. (doi: 10.1161/CIRCULATIONAHA.119.042960)

Sidik, N., Morrow, A., Berry, C. (2020) Human microcirculation in ischemic heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 40, pp. 11-13. (doi: 10.1161/ATVBAHA.119.313579)

Heggie, R., Wu, O., Boyd, K., Lee, M. M.Y., Petrie, M. C., McEntegart, M., Berry, C. (2020) Does routine invasive management benefit patients presenting with an acute coronary syndrome and a history of bypass surgery? The use of clinical outcomes compared with cost-effectiveness outcomes.

McCartney, P. J., Maznyczka, A. M., Eteiba, H., McEntegart, M., Oldroyd, K. G., Greenwood, J. P., Mareida, N., Schmitt, M., McCann, G. P., Fairbairn, T., McAlindon, E., Tait, C., Welsh, P., Sattar, N., Orchard, V., Corcoran, D., Ford, T. J., Radjenovic, A., Ford, I., McConnachie, A., Berry, C. (2020) Low-dose alteplase during primary percutaneous coronary intervention according to ischemic time. Journal of the American College of Cardiology, 75, pp. 1406-1421. (doi: 10.1016/j.jacc.2020.01.041)

Baillie, G., Tibbo, A. (2020) Phosphodiesterase 4B: master regulator of brain signaling. Cells, 9, (doi: 10.3390/cells9051254)

2019

Tardif, J.-C. et al. (2019) Efficacy and safety of low-dose colchicine after myocardial infarction. New England Journal of Medicine, 381, pp. 2497-2505. (doi: 10.1056/NEJMoa1912388)

Dewan, P., Rorth, R., Raparelli, V., Campbell, R. T., Shen, L., Jhund, P. S., Petrie, M. C., Anand, I. S., Carson, P. E., Desai, A. S., Granger, C. B., Køber, L., Komajda, M., McKelvie, R. S., O'Meara, E., Pfeffer, M. A., Pitt, B., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Sex-related differences in heart failure with preserved ejection fraction. Circulation: Heart Failure, 12, (doi: 10.1161/CIRCHEARTFAILURE.119.006539)

Nagel, E., Berry, C. (2019) Magnetic resonance perfusion or fractional flow reserve in coronary disease. Reply. New England Journal of Medicine, 381, pp. 2277-2278. (doi: 10.1056/NEJMc1913968)

Ford, T. J., Yii, E., Sidik, N., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., McCartney, P., Corcoran, D., Collison, D., Rush, C., Stanley, B., McConnachie, A., Sattar, N., Touyz, R. M., Oldroyd, K. G., Berry, C. (2019) Ischemia and no obstructive coronary artery disease: prevalence and correlates of coronary vasomotion disorders. Circulation: Cardiovascular Interventions, 12, (doi: 10.1161/CIRCINTERVENTIONS.119.008126)

Avtaar Singh, S. S., Das De, S., Rushton, S., Berry, C., Al-Attar, N. (2019) PREDICTA: a model to predict primary graft dysfunction after adult heart transplantation in the United Kingdom. Journal of Cardiac Failure, 25, pp. 971-977. (doi: 10.1016/j.cardfail.2019.07.009)

Adamson, C., Rocchiccioli, P., Brogan, R., Berry, C., Ford, T. J. (2019) Post-operative myocardial infarction following aortic root surgery with coronary reimplantation: a case series treated with percutaneous coronary intervention. European Heart Journal: Case Reports, 3, pp. 1-6. (doi: 10.1093/ehjcr/ytz181)

Sharma, V. et al. (2019) Report from the Annual Conference of the British Society of Echocardiography, November 2017, Edinburgh International Conference Centre, Edinburgh. Echo Research and Practice, 6, pp. M1-M2. (doi: 10.1530/ERP-19-0056)

McMurray, J. J.V. et al. (2019) Dapagliflozin in patients with heart failure and reduced ejection fraction. New England Journal of Medicine, 381, pp. 1995-2008. (doi: 10.1056/NEJMoa1911303)

Bularga, A., Lee, K. K., Stewart, S., Ferry, A. V., Chapman, A. R., Marshall, L., Strachan, F. E., Cruickshank, A., Maguire, D., Berry, C., Findlay, I., Shah, A. S.V., Newby, D. E., Mills, N. L., Anand, A. (2019) High-sensitivity troponin and the application of risk stratification thresholds in patients with suspected acute coronary syndrome. Circulation, 140, pp. 1557-1568. (doi: 10.1161/CIRCULATIONAHA.119.042866)

Davies, V., Noè, U., Lazarus, A., Gao, H., Macdonald, B., Berry, C., Luo, X., Husmeier, D. (2019) Fast parameter inference in a biomechanical model of the left ventricle by using statistical emulation. Journal of the Royal Statistical Society: Series C (Applied Statistics), 68, pp. 1555-1576. (doi: 10.1111/rssc.12374)

Stirrat, C. G., Alam, S., MacGillivray, T. J., Gray, C., Dweck, M. R., Jones, V., Wallace, W., Payne, J. R., Prasad, S. K., Gardner, R. S., Petrie, M. C., Mirsadraee, S., Henriksen, P., Newby, D. E., Semple, S. (2019) Ferumoxytol-enhanced MRI in patients with prior cardiac transplantation. Open Heart, 6, (doi: 10.1136/openhrt-2019-001115)

Howlett, J. G., Stebbins, A., Petrie, M. C., Jhund, P. S., Castelvecchio, S., Cherniavsky, A., Sueta, C. A., Roy, A., Piña, I. L., Wurm, R., Drazner, M. H., Andersson, B., Batlle, C., Senni, M., Chrzanowski, L., Merkely, B., Carson, P., Desvigne-Nickens, P. M., Lee, K. L., Velazquez, E. J., Al-Khalidi, H. R. (2019) CABG improves outcomes in patients with ischemic cardiomyopathy 10-year follow-up of the STICH trial. JACC: Heart Failure, 7, pp. 878-887. (doi: 10.1016/j.jchf.2019.04.018)

Rahman, H., Corcoran, D., Aetesam-Ur-Rahman, M., Hoole, S. P., Berry, C., Perera, D. (2019) Diagnosis of patients with angina and non-obstructive coronary disease in the catheter laboratory. Heart, 105, pp. 1536-1542. (doi: 10.1136/heartjnl-2019-315042)

Hausenloy, D. J. et al. (2019) Effect of remote ischaemic conditioning on clinical outcomes in patients with acute myocardial infarction (CONDI-2/ERIC-PPCI): a single-blind randomised controlled trial. Lancet, 394, pp. 1415-1424. (doi: 10.1016/S0140-6736(19)32039-2)

Packer, M. et al. (2019) Evaluation of the effect of sodium–glucose co‐transporter 2 inhibition with empagliflozin on morbidity and mortality of patients with chronic heart failure and a reduced ejection fraction: rationale for and design of the EMPEROR‐Reduced trial. European Journal of Heart Failure, 21, pp. 1270-1278. (doi: 10.1002/ejhf.1536)

Anker, S. D. et al. (2019) Evaluation of the effects of sodium–glucose co‐transporter 2 inhibition with empagliflozin on morbidity and mortality in patients with chronic heart failure and a preserved ejection fraction: rationale for and design of the EMPEROR‐Preserved Trial. European Journal of Heart Failure, 21, pp. 1279-1287. (doi: 10.1002/ejhf.1596)

Adamson, P. D., Williams, M. C., Dweck, M. R., Mills, N. L., Boon, N. A., Daghem, M., Bing, R., Moss, A. J., Mangion, K., Flather, M., Forbes, J., Hunter, A., Norrie, J., Shah, A. S.V., Timmis, A. D., van Beek, E. J.R., Ahmadi, A. A., Leipsic, J., Narula, J., Newby, D. E., Roditi, G., McAllister, D. A., Berry, C. (2019) Guiding therapy by coronary CT angiography improves outcomes in patients with stable chest pain. Journal of the American College of Cardiology, 74, pp. 2058-2070. (doi: 10.1016/j.jacc.2019.07.085)

Platz, E., Campbell, R. T., Claggett, B., Lewis, E. F., Groarke, J. D., Docherty, K. F., Lee, M. M.Y., Merz, A. A., Silverman, M., Swamy, V., Lindner, M., Rivero, J., Solomon, S. D., McMurray, J. J.V. (2019) Lung ultrasound in acute heart failure: prevalence of pulmonary congestion and short- and long-term outcomes. JACC: Heart Failure, 7, pp. 849-858. (doi: 10.1016/j.jchf.2019.07.008)

Blair, C. M., Baillie, G. S. (2019) Reshaping cAMP nanodomains through targeted disruption of compartmentalised phosphodiesterase signalosomes. Biochemical Society Transactions, 47, pp. 1405-1414. (doi: 10.1042/BST20190252)

Lee, K. K., Ferry, A. V., Anand, A., Strachan, F. E., Chapman, A. R., Kimenai, D. M., Meex, S. J.R., Berry, C., Findlay, I., Reid, A., Cruickshank, A., Gray, A., Collinson, P. O., Apple, F. S., McAllister, D. A., Maguire, D., Fox, K. A.A., Newby, D. E., Tuck, C., Keerie, C., Weir, C. J., Shah, A. S.V., Mills, N. L. (2019) Sex-specific thresholds of high-sensitivity troponin in patients with suspected acute coronary syndrome. Journal of the American College of Cardiology, 74, pp. 2032-2043. (doi: 10.1016/j.jacc.2019.07.082)

Lee, M. M.Y., Sattar, N., McMurray, J. J.V., Packard, C. J. (2019) Statins in the prevention and treatment of heart failure: a review of the evidence. Current Atherosclerosis Reports, 21, (doi: 10.1007/s11883-019-0800-z)

Baillie, G. S., Tejeda, G. S., Kelly, M. P. (2019) Therapeutic targeting of 3’,5’-cyclic nucleotide phosphodiesterases: inhibition and beyond. Nature Reviews Drug Discovery, 18, pp. 770-796. (doi: 10.1038/s41573-019-0033-4)

Tibbo, A. J., Tejeda, G. S., Baillie, G. S. (2019) Understanding PDE4's function in Alzheimer's disease; a target for novel therapeutic approaches. Biochemical Society Transactions, 47, pp. 1557-1565. (doi: 10.1042/BST20190763)

Nicolau, J. C., Stevens, S. R., Al-Khalidi, H. R., Jatene, F. B., Furtado, R. H.M., Dallan, L. A.O., Lisboa, L. A.F., Desvigne-Nickens, P., Haddad, H., Jolicoeur, E. M., Petrie, M. C., Doenst, T., Michler, R. E., Ohman, E. M., Maddury, J., Ali, I., Deja, M. A., Rouleau, J. L., Velazquez, E. J., Hill, J. A. (2019) Does prior coronary angioplasty affect outcomes of surgical coronary revascularization? Insights from the STICH trial. International Journal of Cardiology, 291, pp. 36-41. (doi: 10.1016/j.ijcard.2019.03.029)

Kristensen, S. L., Rorth, R., Jhund, P. S., Docherty, K., Sattar, N., Preiss, D., Kober, L., Petrie, M. C., McMurray, J. J.V. (2019) Cardiovascular, mortality and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials. Lancet Diabetes and Endocrinology, 7, pp. 776-785. (doi: 10.1016/S2213-8587(19)30249-9)

Dérimay, F., Johnson, N. P., Zimmermann, F. M., Adjedj, J., Witt, N., Hennigan, B., Koo, B.‐K., Barbato, E., Esposito, G., Trimarco, B., Rioufol, G., Park, S.‐J., Baptista, S. B., Chrysant, G. S., Leone, A. M., Jeremias, A., Berry, C., De Bruyne, B., Oldroyd, K. G., Pijls, N. H.J., Fearon, W. F. (2019) Predictive factors of discordance between the instantaneous wave‐free ratio and fractional flow reserve. Catheterization and Cardiovascular Interventions, 94, pp. 356-363. (doi: 10.1002/ccd.28116)

Avtaar Singh, S. S., Dalzell, J. R., Berry, C., Al-Attar, N. (2019) Primary graft dysfunction after heart transplantation: a thorn amongst the roses. Heart Failure Reviews, 24, pp. 805-820. (doi: 10.1007/s10741-019-09794-1)

Yang, Y., Gao, H., Berry, C., Radjenovic, A., Husmeier, D. (2019) Quantification of Myocardial Perfusion Lesions Using Spatially Variant Finite Mixture Modelling of DCE-MRI. (doi: 10.11159/icsta19.26)

Husmeier, D., Lazarus, A., Noè, U., Davies, V., Borowska, A., Macdonald, B., Gao, H., Berry, C., Luo, X. (2019) Statistical Emulation of Cardiac Mechanics: an Important Step Towards a Clinical Decision Support System. (doi: 10.11159/icsta19.29)

Wang, L., Morotti, S., Tapa, S., Francis Stuart, S. D., Jiang, Y., Wang, Z., Myles, R. C., Brack, K. E., Ng, G. A., Bers, D. M., Grandi, E., Ripplinger, C. M. (2019) Different paths, same destination: divergent action potential responses produce conserved cardiac fight-or-flight response in mouse and rabbit hearts. Journal of Physiology, 597, pp. 3867-3883. (doi: 10.1113/jp278016)

Johnson, N. P., Li, W., Chen, X., Hennigan, B., Watkins, S., Berry, C., Fearon, W. F., Oldroyd, K. G. (2019) Diastolic pressure ratio: new approach and validation vs. the instantaneous wave-free ratio. European Heart Journal, 40, pp. 2585-2594. (doi: 10.1093/eurheartj/ehz230)

Rørth, R., Dewan, P., Kristensen, S. L., Jhund, P. S., Petrie, M. C., Køber, L., McMurray, J. J.V. (2019) Efficacy of an implantable cardioverter-defibrillator in patients with diabetes and heart failure and reduced ejection fraction. Clinical Research in Cardiology, 108, pp. 868-877. (doi: 10.1007/s00392-019-01415-z)

Shen, L., Rørth, R., Cosmi, D., Kristensen, S. L., Petrie, M. C., Cosmi, F., Latini, R., Køber, L., Anand, I. S., Carson, P. E., Granger, C. B., Komajda, M., McKelvie, R. S., Solomon, S. D., Staszewsky, L., Swedberg, K., Huynh, T., Zile, M. R., Jhund, P. S., McMurray, J. J.V. (2019) Insulin treatment and clinical outcomes in patients with diabetes and heart failure with preserved ejection fraction. European Journal of Heart Failure, 21, pp. 974-984. (doi: 10.1002/ejhf.1535)

Lee, M. M.Y. et al. (2019) Invasive versus medical management in patients with prior coronary artery bypass surgery with a non-ST segment elevation acute coronary syndrome: a pilot randomized controlled trial. Circulation: Cardiovascular Interventions, 12, (doi: 10.1161/CIRCINTERVENTIONS.119.007830)

Crea, F., Bairey Merz, C. N., Beltrame, J. F., Berry, C., Camici, P. G., Kaski, J. C., Ong, P., Pepine, C. J., Sechtem, U., Shimokawa, H. (2019) Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization. European Heart Journal, 40, pp. 2455-2462. (doi: 10.1093/eurheartj/ehy857)

Whiteley, E. L., Tejeda, G. S., Baillie, G. S., Brandon, N. J. (2019) PDE10A mutations help to unwrap the neurobiology of hyperkinetic disorders. Cellular Signalling, 60, pp. 31-38. (doi: 10.1016/j.cellsig.2019.04.001)

Noè, U., Lazarus, A., Gao, H., Davies, V., Macdonald, B., Mangion, K., Berry, C., Luo, X., Husmeier, D. (2019) Gaussian process emulation to accelerate parameter estimation in a mechanical model of the left ventricle: a critical step towards clinical end-user relevance. Journal of the Royal Society: Interface, 16, (doi: 10.1098/rsif.2019.0114)

Ibanez, B., Aletras, A. H., Arai, A. E., Arheden, H., Bax, J., Berry, C., Bucciarelli-Ducci, C., Croisille, P., Dall'Armellina, E., Dharmakumar, R., Eitel, I., Fernández-Jiménez, R., Friedrich, M. G., García-Dorado, D., Hausenloy, D. J., Kim, R. J., Kozerke, S., Kramer, C. M., Salerno, M., Sánchez-González, J., Sanz, J., Fuster, V. (2019) Cardiac MRI endpoints in myocardial infarction experimental and clinical trials: JACC scientific expert panel. Journal of the American College of Cardiology, 74, pp. 238-256. (doi: 10.1016/j.jacc.2019.05.024)

Omar, F., Findlay, J. E., Carfray, G., Allcock, R. W., Jiang, Z., Moore, C., Muir, A. L., Lannoy, M., Fertig, B. A., Maie, D., Day, J. P., Bolger, G., Baillie, G. S., Schwiebert, E., Klussmann, E., Pyne, N. J., Ong, A. C.M., Bowers, K., Adam, J. M., Adams, D. R., Houslay, M. D., Hendersona, D. J.P. (2019) Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases. Proceedings of the National Academy of Sciences of the United States of America, 116, pp. 13320-13329. (doi: 10.1073/pnas.1822113116)

Ubaid, S., Ford, T. J., Berry, C., Murray, H. M., Wrigley, B., Khan, N., Thomas, M. R., Armesilla, A. L., Townend, J. N., Khogali, S. S., Munir, S., Martins, J., Hothi, S. S., McAlindon, E. J., Cotton, J. M. (2019) Cangrelor versus ticagrelor in patients treated with primary percutaneous coronary intervention: impact on platelet activity, myocardial microvascular function and infarct size: a randomized controlled trial. Thrombosis and Haemostasis, 119, pp. 1171-1181. (doi: 10.1055/s-0039-1688789)

Kettlewell, S., Saxena, P., Dempster, J., Colman, M. A., Myles, R. C., Smith, G. L., Workman, A. J. (2019) Dynamic‐clamping human and rabbit atrial calcium current: narrowing ICaL window abolishes early afterdepolarisations. Journal of Physiology, 597, pp. 3619-3638. (doi: 10.1113/JP277827)

Wongpiyabovorn, J., Soonthornchai, W., Wilantho, A., Palasuk, M., Payungporn, S., Sodsai, P., Poomipak, W., Weschawalit, S., Ruchusatsawat, K., Baillie, G. S., Hirankarn, N., Somboonna, N. (2019) Effect of tarcolimus on skin microbiome in atopic dermatitis. Allergy, 74, pp. 1400-1406. (doi: 10.1111/all.13743)

Niccoli, G., Montone, R. A., Ibanez, B., Thiele, H., Crea, F., Heusch, G., Bulluck, H., Hausenloy, D. J., Berry, C., Stiermaier, T., Camici, P. G., Eitel, I. (2019) Optimized treatment of ST-elevation myocardial infarction: the unmet need to target coronary microvascular obstruction as primary treatment goal to further improve prognosis. Circulation Research, 125, pp. 245-258. (doi: 10.1161/circresaha.119.315344)

Bauersachs, J., König, T., Meer, P., Petrie, M. C., Hilfiker‐Kleiner, D., Mbakwem, A., Hamdan, R., Jackson, A. M., Forsyth, P., Boer, R. A., Mueller, C., Lyon, A. R., Lund, L. H., Piepoli, M. F., Heymans, S., Chioncel, O., Anker, S. D., Ponikowski, P., Seferovic, P. M., Johnson, M. R., Mebazaa, A., Sliwa, K. (2019) Pathophysiology, diagnosis and management of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on peripartum cardiomyopathy. European Journal of Heart Failure, 21, pp. 827-843. (doi: 10.1002/ejhf.1493)

Houslay, K.F., Fertig, B.A., Christian, F., Tibbo, A.J., Ling, J., Findlay, J.E., Houslay, M.D., Baillie, G.S. (2019) Phosphorylation of PDE4A5 by MAPKAPK2 attenuates fibrin degradation via p75 signalling. Journal of Biochemistry, 166, pp. 97-106. (doi: 10.1093/jb/mvz016)

Cleland, J. G.F., Hindricks, G., Petrie, M. (2019) The shocking lack of evidence for implantable cardioverter defibrillators for heart failure; with or without cardiac resynchronization. European Heart Journal, 40, pp. 2128-2130. (doi: 10.1093/eurheartj/ehz409)

Clister, T., Greenwald, E. C., Baillie, G. S., Zhang, J. (2019) AKAP95 organizes a nuclear microdomain to control local cAMP for regulating nuclear PKA. Cell Chemical Biology, 26, pp. 885-891. (doi: 10.1016/j.chembiol.2019.03.003)

Nagel, E., Greenwood, J. P., McCann, G. P., Bettencourt, N., Shah, A. M., Hussain, S. T., Perera, D., Plein, S., Bucciarelli-Ducci, C., Paul, M., Westwood, M. A., Marber, M., Richter, W.-S., Puntmann, V. O., Schwenke, C., Schulz-Menger, J., Das, R., Wong, J., Hausenloy, D. J., Steen, H., Berry, C. (2019) Magnetic resonance perfusion or fractional flow reserve in coronary disease. New England Journal of Medicine, 380, pp. 2418-2428. (doi: 10.1056/NEJMoa1716734)

Van Strijp, D., De Witz, C., Heitkoetter, B., Huss, S., Boegemann, M., Baillie, G. S., Houslay, M. D., Bangma, C., Semjonow, A., Hoffmann, R. (2019) The association of the long prostate cancer expressed PDE4D transcripts to poor patient outcome depends on the tumor’s TMPRSS2-ERG fusion status. Prostate Cancer, 2019, (doi: 10.1155/2019/8107807)

Clark, A. L., Kalra, P. R., Petrie, M. C., Mark, P. B., Tomlinson, L. A., Tomson, C. R.V. (2019) Change in renal function associated with drug treatment in heart failure: national guidance. Heart, 105, pp. 904-910. (doi: 10.1136/heartjnl-2018-314158)

Haig, C., Carrick, D., Carberry, J., Mangion, K., Maznyczka, A., Wetherall, K., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ahmed, N., May, V. T. Y., Ford, I., Radjenovic, A., Welsh, P., Sattar, N., Oldroyd, K. G., Berry, C. (2019) Current smoking and prognosis after acute ST-segment elevation myocardial infarction: new pathophysiological insights. JACC: Cardiovascular Imaging, 12, pp. 993-1003. (doi: 10.1016/j.jcmg.2018.05.022)

Ahmad, F. A., Petrie, M. C., McMurray, J. J.V., Lang, N. N. (2019) Personalized medicine and hospitalization for heart failure: if we understand it, we may be successful in treating it. European Journal of Heart Failure, 21, pp. 699-702. (doi: 10.1002/ejhf.1463)

Maznyczka, A. M., Oldroyd, K. G., McCartney, P., McEntegart, M., Berry, C. (2019) The potential use of the index of microcirculatory resistance to guide stratification of patients for adjunctive therapy in acute myocardial infarction. JACC: Cardiovascular Interventions, 12, pp. 951-966. (doi: 10.1016/j.jcin.2019.01.246)

Ford, T., Berry, C. (2019) How to diagnose and manage angina without obstructive coronary artery disease: Lessons from the British Heart Foundation CorMicA trial. Interventional Cardiology Review, 14, pp. 76-82. (doi: 10.15420/icr.2019.04.R1)

Vagena, E., Ryu, J. K., Baeza-Raja, B., Walsh, N. M., Syme, C., Day, J. P., Houslay, M., Baillie, G. (2019) A high-fat diet promotes depression-like behavior in mice by suppressing hypothalamic PKA signalling. Translational Psychiatry, 9, (doi: 10.1038/s41398-019-0470-1)

McMurray, J. J.V. et al. (2019) A trial to evaluate the effect of the sodium–glucose co‐transporter 2 inhibitor dapagliflozin on morbidity and mortality in patients with heart failure and reduced left ventricular ejection fraction (DAPA‐HF) European Journal of Heart Failure, 21, pp. 665-675. (doi: 10.1002/ejhf.1432)

Singh, A., Horsfield, M. A., Bekele, S., Greenwood, J. P., Dawson, D. K., Berry, C., Hogrefe, K., Kelly, D. J., Houston, J. G., Guntur Ramkumar, P., Uddin, A., Suzuki, T., McCann, G. P. (2019) Aortic stiffness in aortic stenosis assessed by cardiovascular MRI: a comparison between bicuspid and tricuspid valves. European Radiology, 29, pp. 2340-2349. (doi: 10.1007/s00330-018-5775-6)

Dewan, P. et al. (2019) Heart failure with reduced ejection fraction: comparison of patient characteristics and clinical outcomes within Asia and between Asia, Europe and the Americas. European Journal of Heart Failure, 21, pp. 577-587. (doi: 10.1002/ejhf.1347)

Shen, L., Jhund, P. S., Docherty, K. F., Petrie, M. C., Anand, I. S., Carson, P. E., Desai, A. S., Granger, C. B., Komajda, M., McKelvie, R. S., Pfeffer, M. A., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Prior pacemaker implantation and clinical outcomes in patients with heart failure and preserved ejection fraction. JACC: Heart Failure, 7, pp. 418-427. (doi: 10.1016/j.jchf.2018.12.006)

Wolsk, E., Kaye, D., Komtebedde, J., Shah, S. J., Borlaug, B. A., Burkhoff, D., Kitzman, D. W., Lam, C. S.P., van Veldhuisen, D. J., Ponikowski, P., Petrie, M. C., Hassager, C., Møller, J. E., Gustafsson, F. (2019) Central and peripheral determinants of exercise capacity in heart failure patients with preserved ejection fraction. JACC: Heart Failure, 7, pp. 321-332. (doi: 10.1016/j.jchf.2019.01.006)

Maznyczka, A. M., Carrick, D., Carberry, J., Mangion, K., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Ford, I., Welsh, P., Sattar, N., Oldroyd, K. G., Berry, C. (2019) Sex-based associations with microvascular injury and outcomes after ST-segment elevation myocardial infarction. Open Heart, 6, (doi: 10.1136/openhrt-2018-000979)

Pettit, S. J., Petrie, M. C. (2019) Transplantation of hearts donated after circulatory-determined death: a song of fire and ice. Circulation: Heart Failure, 12, (doi: 10.1161/CIRCHEARTFAILURE.119.005991)

Mangion, K., Burke, N. M.M., Mccomb, C., Carrick, D., Woodward, R., Berry, C. (2019) Feature-tracking myocardial strain in healthy adults- a magnetic resonance study at 3.0 tesla. Scientific Reports, 9, (doi: 10.1038/s41598-019-39807-w)

Bastug-Özel, Z., Wright, P. T., Kraft, A. E., Pavlovic, D., Howie, J., Froese, A., Fuller, W., Gorelik, J., Shattock, M. J., Nikolaev, V. O. (2019) Heart failure leads to altered β2-adrenoceptor/cyclic adenosine monophosphate dynamics in the sarcolemmal phospholemman/Na,K ATPase microdomain. Cardiovascular Research, 115, pp. 546-555. (doi: 10.1093/cvr/cvy221)

Januzzi, J., Ferreira, J. P., Böhm, M., Kaul, S., Wanner, C., Brueckmann, M., Petrie, M., Ofstad, A.-P., Zeller, C., George, J., Fitchett, D., Zannad, F. (2019) Empagliflozin reduces the risk of a broad spectrum of heart failure outcomes regardless of heart failure status at baseline. European Journal of Heart Failure, 21, pp. 386-388. (doi: 10.1002/ejhf.1419)

Mangion, K., Carrick, D., Clerfond, G., Rush, C., McComb, C., Oldroyd, K. G., Petrie, M. C., Eteiba, H., Lindsay, M., McEntegart, M., Hood, S., Watkins, S., Davie, A., Auger, D. A., Zhong, X., Epstein, F. H., Haig, C. E., Berry, C. (2019) Predictors of segmental myocardial functional recovery in patients after an acute ST-elevation myocardial infarction. European Journal of Radiology, 112, pp. 121-129. (doi: 10.1016/j.ejrad.2019.01.010)

Loader, J., Chan, Y.-K., A Hawley, J., Moholdt, T., McDonald, C. F., Jhund, P., Petrie, M. C., McMurray, J. J., Scuffham, P. A., Ramchand, J., Burrell, L. M., Stewart, S. (2019) Prevalence and profile of "seasonal frequent flyers" with chronic heart disease: analysis of 1598 patients and 4588 patient-years follow-up. International Journal of Cardiology, 279, pp. 126-132. (doi: 10.1016/j.ijcard.2018.12.060)

Mamet, H., Petrie, M. C., Rocchiccioli, P. (2019) Type 1 diabetes mellitus and coronary revascularization. Cardiovascular Endocrinology and Metabolism, 8, pp. 35-38. (doi: 10.1097/XCE.0000000000000166)

Avtaar Singh, S. S., Das De, S., Nappi, F., Al-Adhami, A., Hegazy, Y., Dalzell, J., Doshi, H., Sinclair, A., Curry, P., Petrie, M., Berry, C., Al-Attar, N. (2019) Mechanical circulatory support for refractory cardiogenic shock post-acute myocardial infarction-a decade of lessons. Journal of Thoracic Disease, 11, pp. 542-548. (doi: 10.21037/jtd.2019.01.21)

Mangion, K., Carrick, D., Carberry, J., Mahrous, A., McComb, C., Oldroyd, K. G., Eteiba, H., Lindsay, M., McEntegart, M., Hood, S., Petrie, M. C., Watkins, S., Davie, A., Zhong, X., Epstein, F. H., Haig, C. E., Berry, C. (2019) Circumferential strain predicts major adverse cardiovascular events following an acute ST-segment-elevation myocardial infarction. Radiology, 290, pp. 329-337. (doi: 10.1148/radiol.2018181253)

Avtaar Singh, S. S., Banner, N. R., Rushton, S., Simon, A. R., Berry, C., Al-Attar, N. (2019) ISHLT primary graft dysfunction incidence, risk factors and outcome: a UK national study. Transplantation, 103, pp. 336-343. (doi: 10.1097/TP.0000000000002220)

Kaye, D. M., Petrie, M. C., McKenzie, S., Hasenfuβ, G., Malek, F., Post, M., Doughty, R. N., Trochu, J.-N., Gustafsson, F., Lang, I., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Hausleiter, J., Raake, P., Jondeau, G., Bergmann, M. W., Spelman, T., Aytug, H., Ponikowski, P., Hayward, C. (2019) Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction. ESC Heart Failure, 6, pp. 62-69. (doi: 10.1002/ehf2.12350)

Ford, T., Corcoran, D., Sidik, N., Oldroyd, K. G., Rocchiccioli, P., McEntegart, M., Berry, C. (2019) MINOCA: Requirement for definitive diagnostic work-up. Heart, Lung and Circulation, 28, pp. e4-e6. (doi: 10.1016/j.hlc.2018.04.001)

McCartney, P. J., Berry, C. (2019) Redefining successful primary PCI. European Heart Journal, 20, pp. 133-135. (doi: 10.1093/ehjci/jey159)

Berry, C., Sidik, N., Pereira, A. C., Ford, T. J., Touyz, R. M., Kaski, J.-C., Hainsworth, A. H. (2019) Small-vessel disease in the heart and brain: current knowledge, unmet therapeutic need, and future directions. Journal of the American Heart Association, 8, (doi: 10.1161/JAHA.118.011104)

Lee, M. M.Y., Campbell, R. T., Kelly, R., Petrie, M. C., Sonecki, P. (2019) Does “Scar” at Rest Echocardiography Predict Lack of Contractility Reserve at Dobutamine Stress Echocardiography. (doi: 10.1093/ehjci/jey266)

Dewan, P., Rørth, R., Jhund, P. S., Shen, L., Raparelli, V., Petrie, M. C., Abraham, W. T., Desai, A. S., Dickstein, K., Køber, L., Mogensen, U. M., Packer, M., Rouleau, J. L., Solomon, S. D., Swedberg, K., Zile, M. R., McMurray, J. J.V. (2019) Differential impact of heart failure with reduced ejection fraction on men and women. Journal of the American College of Cardiology, 73, pp. 29-40. (doi: 10.1016/j.jacc.2018.09.081)

McCartney, P. J. et al. (2019) Effect of low-dose intracoronary alteplase during primary percutaneous coronary intervention on microvascular obstruction in patients with acute myocardial infarction: a randomized clinical trial. JAMA: Journal of the American Medical Association, 321, pp. 56-68. (doi: 10.1001/jama.2018.19802)

Berry, C., Corcoran, D., Mangion, K. (2019) Cardiovascular health technology assessment: recommendations to improve the quality of evidence. Open Heart, 6, (doi: 10.1136/openhrt-2018-000930)

Mazlan-Kepli, W., Dawson, J., Berry, C., Walters, M. (2019) Cessation of dual antiplatelet therapy and cardiovascular events following acute coronary syndrome. Heart, 105, pp. 67-74. (doi: 10.1136/heartjnl-2018-313148)

Lee, M. M. Y., McMurray, J. J.V., Lorenzo-Almorós, A., Kristensen, S. L., Sattar, N., Jhund, P. S., Petrie, M. C. (2019) Diabetic cardiomyopathy. Heart, 105, pp. 337-345. (doi: 10.1136/heartjnl-2016-310342)

Morrow, A., Nordin, S., O'Boyle, P., Berry, C. (2019) 'Acute micro-coronary syndrome': detailed coronary physiology in a patient with Takotsubo cardiomyopathy. BMJ Case Reports, 12, (doi: 10.1136/bcr-2019-229618)

Purnama Sidik, N., McCartney, P., Berry, C. (2019) Coronary microvascular disease. Springer

Rush, C. J., Petrie, M. C. (2019) Heart failure with preserved ejection fraction. Springer

Tibbo, A. J., Busiau, T., Baillie, G. S. (2019) Methods to investigate arrestins in complex with phosphodiesterases. Springer

Corcoran, D., Ford, T. J., Berry, C. (2019) Stable coronary syndromes. Springer

Blair, C. M., Walsh, N., Littman, B. H., Marcoux, F. W., Baillie, G. S. (2019) Targeting B-Raf inhibitor resistant melanoma with novel cell penetrating peptide disrupters of PDE8A – C-Raf. BMC Cancer, 19, (doi: 10.1186/s12885-019-5489-4)

2018

Ford, T. J., Stanley, B., Good, R., Rocchiccioli, P., McEntegart, M., Watkins, S., Eteiba, H., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., McGeoch, R., McDade, R., Yii, E., Sidik, N., McCartney, P., Corcoran, D., Collison, D., Rush, C., McConnachie, A., Touyz, R., Oldroyd, K., Berry, C. (2018) Stratified medical therapy using invasive coronary function testing in angina: CorMicA trial. Journal of the American College of Cardiology, 72, pp. 2841-2855. (doi: 10.1016/j.jacc.2018.09.006)

Ford, T. J., Rocchiccioli, P., Good, R., McEntegart, M., Eteiba, H., Watkins, S., Shaukat, A., Lindsay, M., Robertson, K., Hood, S., Yii, E., Sidik, N., Harvey, A., Montezano, A. C., Beattie, E., Haddow, L., Oldroyd, K. G., Touyz, R. M., Berry, C. (2018) Systemic microvascular dysfunction in microvascular and vasospastic angina. European Heart Journal, 39, pp. 4086-4097. (doi: 10.1093/eurheartj/ehy529)

Strembitska, A., Mancini, S. J., Gamwell, J. M., Palmer, T. M., Baillie, G. S., Salt, I. P. (2018) A769662 inhibits insulin-stimulated Akt activation in human macrovascular endothelial cells independent of AMP-activated protein kinase. International Journal of Molecular Sciences, 19, (doi: 10.3390/ijms19123886)

Rossitto, G., Touyz, R. M., Petrie, M. C., Delles, C. (2018) Much Ado about N...atrium: modelling tissuesodium as a highly sensitive marker of subclinicaland localized oedema. Clinical Science, 132, pp. 2609-2613. (doi: 10.1042/CS20180575)

Campbell, R. T., Petrie, M. C., McMurray, J. J.V. (2018) Redefining heart failure phenotypes based on ejection fraction. European Journal of Heart Failure, 20, pp. 1634-1635. (doi: 10.1002/ejhf.1325)

Henry, A. D., MacQuaide, N., Burton, F.L., Rankin, A.C., Rowan, E.G., Drummond, R.M. (2018) Spontaneous Ca2+ transients in rat pulmonary vein cardiomyocytes are increased in frequency and become more synchronous following electrical stimulation. Cell calcium, 76, pp. 36-47. (doi: 10.1016/j.ceca.2018.09.001)

Campbell, R. T., Petrie, M. C., McMurray, J. J.V. (2018) Talking to patients with heart failure about end of life. European Journal of Heart Failure, 20, pp. 1763-1765. (doi: 10.1002/ejhf.1321)

Dobbin, S. J.H., Cameron, A. C., Petrie, M. C., Jones, R. J., Touyz, R. M., Lang, N. N. (2018) Toxicity of cancer therapy: what the cardiologist needs to know about angiogenesis inhibitors. Heart, 104, pp. 1995-2002. (doi: 10.1136/heartjnl-2018-313726)

Connolly, A., Kelly, A., Campos, F. O., Myles, R., Smith, G., Bishop, M. J. (2018) Ventricular endocardial tissue geometry affects stimulus threshold and effective refractory period. Biophysical Journal, 115, pp. 2486-2498. (doi: 10.1016/j.bpj.2018.11.003)

Maziarz, M., Broselid, S., DiGiacomo, V., Park, J.-C., Luebbers, A., Garcia-Navarrete, L., Blanco-Canosa, J. B., Baillie, G. S., Garcia-Marcos, M. (2018) A biochemical and genetic discovery pipeline identifies PLCδ4b as a non-receptor activator of heterotrimeric G proteins. Journal of Biological Chemistry, 293, pp. 16964-16983. (doi: 10.1074/jbc.RA118.003580)

MacDonald, E., Quinn, T. A. (2018) Mechanical Determinants of the Chronotropic Response to Sinoatrial Stretch. (doi: 10.1016/j.yjmcc.2018.07.030)

Kristensen, S. L., Rørth, R., Jhund, P. S., Shen, L., Lee, M. M.Y., Petrie, M. C., Køber, L., McMurray, J. J.V. (2018) Microvascular complications in diabetes patients with heart failure and reduced ejection fraction-insights from the Beta-blocker Evaluation of Survival Trial. European Journal of Heart Failure, 20, pp. 1549-1556. (doi: 10.1002/ejhf.1201)

Rush, C. J., Campbell, R. T., Jhund, P. S., Petrie, M. C., McMurray, J. J.V. (2018) Association is not causation: treatment effects cannot be estimated from observational data in heart failure. European Heart Journal, 39, pp. 3417-3438. (doi: 10.1093/eurheartj/ehy407)

Shah, S. J. et al. (2018) One-year safety and clinical outcomes of a transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction in the reduce elevated left atrial pressure in patients with heart failure (REDUCE LAP-HF I) trial: a randomized clinical trial. JAMA Cardiology, 3, pp. 968-977. (doi: 10.1001/jamacardio.2018.2936)

van Meer, B. J., Sala, L., Tertoolen, L. G.J., Smith, G. L., Burton, F. L., Mummery, C. L. (2018) Quantification of muscle contraction in vitro and in vivo using MUSCLEMOTION software: from stem cell-derived cardiomyocytes to zebrafish and human hearts. Current Protocols in Human Genetics, 99, (doi: 10.1002/cphg.67)

Berry, C., Mangion, K., Pathan, F. (2018) Spotlight on strain following myocardial infarction. JACC: Cardiovascular Imaging, 11, pp. 1445-1447. (doi: 10.1016/j.jcmg.2018.01.004)

Elliott, C., Rojo, A. I., Ribe, E., Broadstock, M., Xia, W., Morin, P., Semenov, M., Baillie, G., Cuadrado, A., Al-Shawi, R., Ballard, C. G., Simons, P., Killick, R. (2018) A role for APP in Wnt signalling links synapse loss with β-amyloid production. Translational Psychiatry, 8, (doi: 10.1038/s41398-018-0231-6)

Puntmann, V. O., Valbuena, S., Hinojar, R., Petersen, S. E., Greenwood, J. P., Kramer, C. M., Kwong, R. Y., McCann, G. P., Berry, C., Nagel, E. (2018) Society for Cardiovascular Magnetic Resonance (SCMR) expert consensus for CMR imaging endpoints in clinical research: part I - analytical validation and clinical qualification. Journal of Cardiovascular Magnetic Resonance, 20, (doi: 10.1186/s12968-018-0484-5)

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Colman, M. A., Saxena, P., Kettlewell, S., Workman, A. J. (2018) Description of the human atrial action potential derived from a single, congruent data source: novel computational models for integrated experimental-numerical study of atrial arrhythmia mechanisms. Frontiers in Physiology, 9, (doi: 10.3389/fphys.2018.01211)

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Corcoran, D., Young, R., Adlam, D., McConnachie, A., Mangion, K., Ripley, D., Cairns, D., Brown, J., Bucciarelli-Ducci, C., Baumbach, A., Kharbanda, R., Oldroyd, K. G., McCann, G. P., Greenwood, J. P., Berry, C. (2018) Coronary microvascular dysfunction in patients with stable coronary artery disease: the CE-MARC 2 coronary physiology sub-study. International Journal of Cardiology, 266, pp. 7-14. (doi: 10.1016/j.ijcard.2018.04.061)

McDowell, K., Petrie, M. C., Raihan, N. A., Logue, J. (2018) Effects of intentional weight loss in patients with obesity and heart failure: a systematic review. Obesity Reviews, 19, pp. 1189-1204. (doi: 10.1111/obr.12707)

Carrick, D., Haig, C., Maznyczka, A. M., Carberry, J., Mangion, K., Ahmed, N., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Radjenovic, A., Welsh, P., Sattar, N., Wetherall, K., Oldroyd, K. G., Berry, C. (2018) Hypertension, microvascular pathology and prognosis after an acute myocardial infarction. Hypertension, 72, pp. 720-730. (doi: 10.1161/HYPERTENSIONAHA.117.10786)

McEntegart, M. B., Corcoran, D., Carrick, D., Clerfond, G., Sidik, N., Collison, D., Robertson, K. R., Shaukat, A., Watkins, S., Rocchicholi, P. R., Eteiba, H., Petrie, M. P., Lindsay, M. M., Oldroyd, K. G., Berry, C. (2018) Incidence of procedural myocardial infarction and cardiac magnetic resonance imaging-detected myocardial injury following percutaneous coronary intervention with rotational atherectomy. EuroIntervention, 14, pp. 819-823. (doi: 10.4244/EIJ-D-17-01077)

Kim, S. S., Yamamoto, M. H., Maehara, A., Sidik, N., Koyama, K., Berry, C., Oldroyd, K. G., Mintz, G. S., McEntegart, M. (2018) Intravascular ultrasound assessment of the effects of rotational atherectomy in calcified coronary artery lesions. International Journal of Cardiovascular Imaging, 34, pp. 1365-1371. (doi: 10.1007/s10554-018-1352-y)

Engelhardt, B., Holze, J., Elliott, C., Baillie, G.S., Kschischo, M., Fröhlich, H. (2018) Modelling and mathematical analysis of the M2 receptor-dependent joint signalling and secondary messenger network in CHO cells. Mathematical Medicine and Biology, 35, pp. 279-297. (doi: 10.1093/imammb/dqx003)

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Kobayashi, Y., Lønborg, J., Jong, A., Nishi, T., De Bruyne, B., Høfsten, D. E., Kelbæk, H., Layland, J., Nam, C.-W., Pijls, N. H.J., Tonino, P. A.L., Warnøe, J., Oldroyd, K. G., Berry, C., Engstrøm, T., Fearon, W. F. (2018) Prognostic value of the residual SYNTAX score after functionally complete revascularization in ACS. Journal of the American College of Cardiology, 72, pp. 1321-1329. (doi: 10.1016/j.jacc.2018.06.069)

Svanerud, J., Ahn, J.-M., Jeremias, A., van 't Veer, M., Gore, A., Maehara, A., Crowley, A., Pijls, N. H.J., De Bruyne, B., Johnson, N. P., Hennigan, B., Watkins, S., Berry, C., Oldroyd, K. G., Park, S.-J., Ali, Z. A. (2018) Validation of a novel non-hyperaemic index of coronary artery stenosis severity: the Resting Full-cycle Ratio (VALIDATE RFR) study. EuroIntervention, 14, pp. 806-814. (doi: 10.4244/EIJ-D-18-00342)

Campbell, R. T., Petrie, M. C., Jackson, C. E., Jhund, P. S., Wright, A., Gardner, R. S., Sonecki, P., Pozzi, A., McSkimming, P., McConnachie, A., Finlay, F., Davidson, P., Denvir, M. A., Johnson, M. J., Hogg, K. J., McMurray, J. J.V. (2018) Which patients with heart failure should receive specialist palliative care? European Journal of Heart Failure, 20, pp. 1338-1347. (doi: 10.1002/ejhf.1240)

Ford, T. J., McEntegart, M., Berry, C., Oldroyd, K. G. (2018) Arterial access for invasive coronary angiography: the 'left backhander' Heart, Lung and Circulation, 27, pp. e98-e99. (doi: 10.1016/j.hlc.2018.02.021)

Yew, S. N., Carrick, D., Corcoran, D., Ahmed, N., Carberry, J., May, V. T. Y., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davie, A., Mahrous, A., Mordi, I., Ford, I., Oldroyd, K. G., Berry, C. (2018) Coronary thermodilution waveforms after acute reperfused ST‐segment–elevation myocardial infarction: relation to microvascular obstruction and prognosis. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.008957)

Wessler, J., Kaye, D., Gustafsson, F., Petrie, M. C., Hasenfuβ, G., Lam, C. S.P., Borlaug, B. A., Komtebedde, J., Feldman, T., Shah, S. J., Burkhoff, D. (2018) Impact of baseline hemodynamics on the effects of a transcatheter interatrial shunt device in heart failure with preserved ejection fraction. Circulation: Heart Failure, 11, (doi: 10.1161/CIRCHEARTFAILURE.117.004540)

Daly, J. P., Whiteley, E., Freeley, M., Long, A., Malacrida, B., Kiely, P., Baillie, G. S. (2018) RAB40C regulates RACK1 stability via the ubiquitin-proteasome system. Future Science OA, 4, (doi: 10.4155/fsoa-2018-0022)

Shah, S. V., Zimmermann, F. M., Johnson, N. P., Nishi, T., Kobayashi, Y., Witt, N., Berry, C., Jeremias, A., Koo, B.-K., Esposito, G., Rioufol, G., Park, S.-J., Oldroyd, K. G., Barbato, E., Pijls, N. H.J., De Bruyne, B., Fearon, W. F. (2018) Sex differences in adenosine-free coronary pressure indexes: a CONTRAST substudy. JACC: Cardiovascular Interventions, 11, pp. 1454-1463. (doi: 10.1016/j.jcin.2018.03.030)

Ford, T. J., Corcoran, D., Sidik, N., McEntegart, M., Berry, C. (2018) Coronary microvascular dysfunction: Assessment of both structure and function. Journal of the American College of Cardiology, 72, pp. 584-586. (doi: 10.1016/j.jacc.2018.03.545)

van Strijp, D., de Witz, C., Vos, P. C., den Biezen, E., van Brussel, A., Wrobel, J., Baillie, G. S., Tennstedt, P., Schlomm, T., Heitkötter, B., Huss, S., Bögemann, M., Houslay, M. D., Bangma, C. H., Semjonow, A., Hoffmann, R. (2018) The prognostic PDE4D7 score in a diagnostic biopsy prostate cancer patient cohort with longitudinal biological outcomes. Prostate Cancer, 2018, (doi: 10.1155/2018/5821616)

Findlay, I., Morris, T., Zhang, R., Mccowan, C., Shield, S., Forbes, B., McConnachie, A., Mangion, K., Berry, C. (2018) Linking hospital patient records for suspected or established acute coronary syndrome in a complex secondary care system: a proof-of-concept e-registry in NHS Scotland. European Heart Journal: Quality of Care and Clinical Outcomes, 4, pp. 155-167. (doi: 10.1093/ehjqcco/qcy007)

Ford, T. J., Corcoran, D., Oldroyd, K. G., McEntegart, M., Rocchiccioli, P., Watkins, S., Brooksbank, K., Padmanabhan, S., Sattar, N., Briggs, A., McConnachie, A., Touyz, R., Berry, C. (2018) Rationale and design of the British Heart Foundation (BHF) Coronary Microvascular Angina (CorMicA) stratified medicine clinical trial. American Heart Journal, 201, pp. 86-94. (doi: 10.1016/j.ahj.2018.03.010)

Rørth, R., Jhund, P. S., Mogensen, U. M., Kristensen, S. L., Petrie, M. C., Køber, L., McMurray, J. J.V. (2018) Risk of incident heart failure in patients with diabetes and asymptomatic left ventricular systolic dysfunction. Diabetes Care, 41, pp. 1285-1291. (doi: 10.2337/dc17-2583)

Ford, T. J., McCartney, P., Corcoran, D., Collison, D., Hennigan, B., McEntegart, M., Hildick-Smith, D., Oldroyd, K. G., Berry, C. (2018) Single versus two-stent strategies for coronary bifurcation lesions: a systematic review and meta-analysis of randomized trials with long-term follow-up. Journal of the American Heart Association, 7, (doi: 10.1161/JAHA.118.008730)

Sliwa, K., Petrie, M. C., Hilfiker-Kleiner, D., Mebazaa, A., Jackson, A., Johnson, M. R., van der Meer, P., Mbakwem, A., Bauersachs, J. (2018) Long-term prognosis, subsequent pregnancy, contraception and overall management of peripartum cardiomyopathy: practical guidance paper from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. European Journal of Heart Failure, 20, pp. 951-962. (doi: 10.1002/ejhf.1178)

Perera, D., Clayton, T., Petrie, M. C., Greenwood, J. P., O'Kane, P. D., Evans, R., Sculpher, M., Mcdonagh, T., Gershlick, A., de Belder, M., Redwood, S., Carr-White, G., Marber, M. (2018) Percutaneous revascularization for ischemic ventricular dysfunction: rationale and design of the REVIVED-BCIS2 trial: percutaneous coronary intervention for ischemic cardiomyopathy. JACC: Heart Failure, 6, pp. 517-526. (doi: 10.1016/j.jchf.2018.01.024)

Corcoran, D., Ford, T. J., Hsu, L.-Y., Chiribiri, A., Orchard, V., Mangion, K., McEntegart, M., Rocchiccioli, P., Watkins, S., Good, R., Brooksbank, K., Padmanabhan, S., Sattar, N., McConnachie, A., Oldroyd, K. G., Touyz, R. M., Arai, A., Berry, C. (2018) Rationale and design of the Coronary Microvascular Angina Cardiac Magnetic Resonance imaging (CorCMR) diagnostic study: the CorMicA CMR sub-study. Open Heart, 5, (doi: 10.1136/openhrt-2018-000924)

Armfield, K., Baillie, G., Wilson, J.B. (2018) Development of Therapeutic Approaches to Targeting Epstein-Barr virus Related Malignancies.

Bulluck, H., Dharmakumar, R., Arai, A. E., Berry, C., Hausenloy, D. J. (2018) Cardiovascular magnetic resonance in acute ST-segment-elevation myocardial infarction: recent advances, controversies, and future directions. Circulation, 137, pp. 1949-1964. (doi: 10.1161/CIRCULATIONAHA.117.030693)

Jackson, A. M., Dalzell, J. R., Walker, N. L., Coats, C. J., Jhund, P. S., Petrie, M. C. (2018) Peripartum cardiomyopathy: diagnosis and management. Heart, 104, pp. 779-786. (doi: 10.1136/heartjnl-2016-310599)

Seferović, P. M. et al. (2018) Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure, 20, pp. 853-872. (doi: 10.1002/ejhf.1170)

de Inda, M. A., van Strijp, D., den Biezen-Timmermans, E., van Brussel, A., Wrobel, J., van Zon, H., Vos, P., Baillie, G. S., Tennstedt, P., Schlomm, T., Houslay, M. D., Bangma, C., Hoffmann, R. (2018) Validation of cyclic adenosine monophosphate phosphodiesterase-4D7 for its independent contribution to risk stratification in a prostate cancer patient cohort with longitudinal biological outcomes. European Urology Focus, 4, pp. 376-384. (doi: 10.1016/j.euf.2017.05.010)

Mangion, K., Gao, H., Husmeier, D., Luo, X., Berry, C. (2018) Advances in computational modelling for personalised medicine after myocardial infarction. Heart, 104, pp. 550-557. (doi: 10.1136/heartjnl-2017-311449)

Petrie, M. C., Rocchiccioli, P. (2018) Coronary angiography in heart failure: when and why? Uncertainty reigns. Heart, 104, pp. 548-549. (doi: 10.1136/heartjnl-2017-312200)

Lee, M. M.Y. et al. (2018) Non-Invasive Versus Invasive Management in Patients With Prior Coronary Artery Bypass Surgery With a Non-ST Segment Elevation Acute Coronary Syndrome: Comparisons Between the Randomized Controlled Pilot Trial and Registry. (doi: 10.1016/S0735-1097(18)30586-2)

Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo, A. I., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P., Srivastava, D. P., Killick, R. (2018) Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil. Alzheimer's and Dementia, 14, pp. 306-317. (doi: 10.1016/j.jalz.2017.09.008)

Stewart, R. A.H., Szalewska, D., Stebbins, A., Al-Khalidi, H. R., Cleland, J. G.H., Rynkiewicz, A., Drazner, M. H., White, H. D., Mark, D. B., Roy, A., Kosevic, D., Rajda, M., Jasinski, M., Leng, C. Y., Tungsubutra, W., Desvigne-Nickens, P., Velazquez, E. J., Petrie, M. C. (2018) Six-minute walk distance after coronary artery bypass grafting compared with medical therapy in ischaemic cardiomyopathy. Open Heart, 5, (doi: 10.1136/openhrt-2017-000752)

Petrie, M. C., Connelly, D. T., Gardner, R. S. (2018) Who needs an implantable cardioverter-defibrillator? Controversies and opportunities after DANISH. European Journal of Heart Failure, 20, pp. 413-416. (doi: 10.1002/ejhf.1135)

Velazquez, E. J., Petrie, M. C. (2018) CABG or PCI for diabetic patients with left ventricular dysfunction: closing in on the truth? Journal of the American College of Cardiology, 71, pp. 828-831. (doi: 10.1016/j.jacc.2018.01.014)

Sala, L. et al. (2018) MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo. Circulation Research, 122, pp. e5-e16. (doi: 10.1161/CIRCRESAHA.117.312067)

Corcoran, D., Young, R., Cialdella, P., McCartney, P., Bajrangee, A., Hennigan, B., Collison, D., Carrick, D., Shaukat, A., Good, R., Watkins, S., McEntegart, M., Watt, J., Welsh, P., Sattar, N., McConnachie, A., Oldroyd, K.G., Berry, C. (2018) The effects of remote ischaemic preconditioning on coronary artery function in patients with stable coronary artery disease. International Journal of Cardiology, 252, pp. 24-30. (doi: 10.1016/j.ijcard.2017.10.082)

Norman, R., Fuller, W., Calaghan, S. (2018) Caveolae and the cardiac myocyte. Current Opinion in Physiology, 1, pp. 59-67. (doi: 10.1016/j.cophys.2017.08.005)

Adamson, P. D., Hunter, A., Williams, M. C., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Dweck, M. R., Mills, N. L., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D. E. (2018) Diagnostic and prognostic benefits of computed tomography coronary angiography using the 2016 National Institute for Health and Care Excellence guidance within a randomised trial. Heart, 104, pp. 207-214. (doi: 10.1136/heartjnl-2017-311508)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Numé, A.-k., Gislason, G. H.,, Jhund, P. S., Petrie, M. C., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Employment status at time of first hospitalization for heart failure is associated with death and rehospitalization for heart failure. European Journal of Heart Failure, 20, pp. 240-247. (doi: 10.1002/ejhf.1046)

Adamson, P. D., Hunter, A., Madsen, D. M., Shah, A. S.V., McAllister, D. A., Pawade, T. A., Williams, M. C., Berry, C., Boon, N. A., Flather, M., Forbes, J., McLean, S., Roditi, G., Timmis, A. D., van Beek, E. J.R., Dweck, M. R., Mickley, H., Mills, N. L., Newby, D. E. (2018) High-sensitivity cardiac troponin I and the diagnosis of coronary artery disease in patients with suspected angina pectoris. Circulation: Cardiovascular Quality and Outcomes, 11, (doi: 10.1161/CIRCOUTCOMES.117.004227)

Ford, T. J., Corcoran, D., Berry, C. (2018) Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need. Heart, 104, pp. 284-292. (doi: 10.1136/heartjnl-2017-311446)

Fertig, B. A., Baillie, G. S. (2018) PDE4-mediated cAMP signalling. Journal of Cardiovascular Development and Disease, 5, (doi: 10.3390/jcdd5010008)

Feldman, T., Mauri, L., Kahwash, R., Litwin, S., Ricciardi, M. J., van der Harst, P., Penicka, M., Fail, P. S., Kaye, D. M., Petrie, M. C., Basuray, A., Hummel, S. L., Forde-McLean, R., Nielsen, C. D., Lilly, S., Massaro, J. M., Burkhoff, D., Shah, S. J. (2018) Transcatheter interatrial shunt device for the treatment of heart failure with preserved ejection fraction (REDUCE LAP-HF I [Reduce Elevated Left Atrial Pressure in Patients With Heart Failure]): A phase 2, randomized, sham-controlled trial. Circulation, 137, pp. 364-375. (doi: 10.1161/CIRCULATIONAHA.117.032094)

Williams, J. J.L., Al-Otaiq, N., Mullen, W., Burchmore, R., Liu, L., Baillie, G. S., Schaper, F., Pilch, P. F., Palmer, T. M. (2018) Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability. Nature Communications, 9, (doi: 10.1038/s41467-017-02585-y)

Rodrigues, A. L., Brescia, M., Kolshinski, A., Moreira, T. H., Cameron, R. T., Baillie, G., Beirão, P. S.L., Zaccollo, M., Cruz, J. S. (2018) Increase in Ca2+ current by sustained cAMP levels enhances proliferation rate in GH3 cells. Life Sciences, 192, pp. 144-150. (doi: 10.1016/j.lfs.2017.11.040)

Rørth, R., Fosbøl, E. L., Mogensen, U. M., Kragholm, K., Jhund, P. S., Petrie, M. C., Schou, M., Gislason, G. H., McMurray, J. J.V., Torp-Pedersen, C., Køber, L., Kristensen, S. L. (2018) Evidence based therapy and its association with workforce detachment following first hospitalization for heart failure. JACC: Heart Failure, 6, pp. 41-48. (doi: 10.1016/j.jchf.2017.09.019)

Maznyczka, A. M., McCartney, P., Berry, C. (2018) Reference invasive tests of microvascular injury in myocardial infarction. BMJ Open, 104, pp. 90-92. (doi: 10.1136/heartjnl-2017-311695)

Lee, M. M.Y. et al. (2018) Routine Non-invasive vs Invasive Management in Patients With Prior CABG With a NSTE-ACS: a Randomised Controlled Trial. (doi: 10.1136/heartjnl-2018-BCIS.9)

Souteyrand, G., Valladier, M., Amabile, N., Derimay, F., Harbaoui, B., Leddet, P., Barnay, P., Malcles, G., Mulliez, A., Berry, C., Eschalier, R., Combaret, N., Motreff, P. (2018) Diagnosis and management of spontaneously recanalized coronary thrombus guided by optical coherence tomography ― lessons from the French “Lotus Root” registry ― Circulation Journal, 82, pp. 783-790. (doi: 10.1253/circj.cj-17-0810)

Yalla, K., Elliott, C., Day, J.P., Findlay, J., Barratt, S., Hughes, Z.A., Wilson, L., Whiteley, E., Popiolek, M., Li, Y., Dunlop, J., Killick, R., Adams, D.R., Brandon, N.J., Houslay, M.D., Hao, B., Baillie, G.S. (2018) FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system. Molecular Psychiatry, 23, pp. 1278-1286. (doi: 10.1038/mp.2017.138)

Howie, J., Wypijewski, K. J., Plain, F., Tulloch, L. B., Fraser, N. J., Fuller, W. (2018) Greasing the wheels or a spanner in the works? Regulation of the cardiac sodium pump by palmitoylation. Critical Reviews in Biochemistry and Molecular Biology, 53, pp. 175-191. (doi: 10.1080/10409238.2018.1432560)

Lachaud, Q., MacQuaide, N., Burton, F., Smith, G. (2018) High-throughput study of rabbit ventricle action potential populations in MI model. Biophysical Journal, 114, pp. 625A. (doi: 10.1016/j.bpj.2017.11.3377)

Berry, C., Carberry, J., Mangion, K. (2018) How to mend a broken heart? JACC: Cardiovascular Imaging, 11, pp. 420-422. (doi: 10.1016/j.jcmg.2017.02.017)

Rørth, R., Fosbøl, E. L., Kragholm, K., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Torp-Pedersen, C., Gislason, G. H., McMurray, J. J.V., Køber, L., Kristensen, S. L. (2018) Initiation of domiciliary care and nursing home admission following first hospitalization for heart failure: a nationwide cohort study. Clinical Epidemiology, 10, pp. 917-930. (doi: 10.2147/CLEP.S164795)

Layland, J., Tong, D., Lee, M., Berry, C. (2018) ST and T-Wave Abnormality as Footprint of Myocardial Oedema in Non–ST-Elevation Myocardial Infarction. (doi: 10.1016/j.hlc.2018.06.515)

Bouabdallaoui, N. et al. (2018) Society of Thoracic Surgeons risk score and EuroSCORE-2 appropriately assess 30-day postoperative mortality in the STICH trial and a contemporary cohort of patients with left ventricular dysfunction undergoing surgical revascularization. Circulation: Heart Failure, 11, (doi: 10.1161/circheartfailure.118.005531)

2017

Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C., Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)

Van't Veer, M., Pijls, N. H.J., Hennigan, B., Watkins, S., Ali, Z. A., De Bruyne, B., Zimmermann, F. M., van Nunen, L. X., Barbato, E., Berry, C., Oldroyd, K. G. (2017) Comparison of different diastolic resting indexes to iFR: are they all equal? Journal of the American College of Cardiology, 70, pp. 3088-3096. (doi: 10.1016/j.jacc.2017.10.066)

Ford, T. J., Berry, C., De Bruyne, B., Yong, A. C.S., Barlis, P., Fearon, W. F., Ng, M. K.C. (2017) Physiological predictors of acute coronary syndromes: emerging insights from the plaque to the vulnerable patient. JACC: Cardiovascular Interventions, 10, pp. 2539-2547. (doi: 10.1016/j.jcin.2017.08.059)

Logie, L., Van Aalten, L., Knebel, A., Force, T., Hastie, C. J., MacLauchlan, H., Campbell, D. G., Gourlay, R., Prescott, A., Davidson, J., Fuller, W., Sutherland, C. (2017) Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3) Scientific Reports, 7, (doi: 10.1038/s41598-017-17087-6)

Berry, C., McClure, J. D., Oldroyd, K. G. (2017) Meta-analysis of death and myocardial infarction in the DEFINE-FLAIR and iFR-SWEDEHEART trials: a hypothesis generating note of caution. Circulation, 136, pp. 2389-2391. (doi: 10.1161/CIRCULATIONAHA.117.030430)

Hilfiker-Kleiner, D., Haghikia, A., Masuko, D., Nonhoff, J., Held, D., Libhaber, E., Petrie, M. C., Walker, N. L., Podewski, E., Berliner, D., Bauersachs, J., Sliwa, K. (2017) Outcome of subsequent pregnancies in patients with a history of peripartum cardiomyopathy. European Journal of Heart Failure, 19, pp. 1723-1728. (doi: 10.1002/ejhf.808)

Basole, C. P., Nguyen, R. K., Lamothe, K., Vang, A., Clark, R., Baillie, G. S., Epstein, P. M., Brocke, S. (2017) PDE8 controls CD4(+) T cell motility through the PDE8A-Raf-1 kinase signaling complex. Cellular Signalling, 40, pp. 62-72. (doi: 10.1016/j.cellsig.2017.08.007)

Carberry, J., Carrick, D., Haig, C., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M. C., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Davie, A., Mahrous, A., Ford, I., Sattar, N., Welsh, P., Radjenovic, A., Oldroyd, K. G., Berry, C. (2017) Persistence of infarct zone T2 hyperintensity at 6 months after acute ST-elevation myocardial infarction: incidence, pathophysiology and prognostic implications. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006586)

Kristensen, S. L., Jhund, P. S., Lee, M. M.Y., Køber, L., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., McMurray, J. J.V. (2017) Prevalence of prediabetes and undiagnosed diabetes in patients with HFpEF and HFrEF and associated clinical outcomes. Cardiovascular Drugs and Therapy, 31, pp. 545-549. (doi: 10.1007/s10557-017-6754-x)

Holman, R. R., Coleman, R. L., Chan, J. C. N., Chiasson, J.-L., Feng, H., Ge, J., Gerstein, H. C., Gray, R., Huo, Y., Lang, Z., McMurray, J. J., Rydén, L., Schröder, S., Sun, Y., Theodorakis, M. J., Tendera, M., Tucker, L., Tuomilehto, J., Wei, Y., Yang, W., Wang, D., Hu, D., Pan, C., ACE Study Group, (2017) Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial. Lancet Diabetes and Endocrinology, 5, pp. 877-886. (doi: 10.1016/S2213-8587(17)30309-1)

Wong, C. M., Hawkins, N. M., Ezekowitz, J. A., Jhund, P. S., Savu, A., MacDonald, M. R., Kristensen, S. L., Petrie, M. C., McMurray, J. J.V., McAlister, F. A., Kaul, P. (2017) Heart failure in young adults is associated with high mortality: a contemporary population-level analysis. Canadian Journal of Cardiology, 33, pp. 1472-1477. (doi: 10.1016/j.cjca.2017.05.009)

MacDonald, E. A., Stoyek, M. R., Rose, R. A., Quinn, T. A. (2017) Intrinsic regulation of sinoatrial node function and the zebrafish as a model of stretch effects on pacemaking. Progress in Biophysics and Molecular Biology, 130, pp. 198-211. (doi: 10.1016/j.pbiomolbio.2017.07.012)

Rutherford, E., Mangion, K., Mccomb, C., Bell, E., Cockburn, S., Talle, M., Roditi, G., Welsh, P., Woodward, R., Radjenovic, A., Struthers, A. D., Jardine, A., Berry, C., Patel, R. K., Mark, P. B. (2017) Myocardial changes in incident haemodialysis patients over 6-months: an observational cardiac magnetic resonance imaging study. Scientific Reports, 7, (doi: 10.1038/s41598-017-14481-y)

Kobayashi, Y., Johnson, N. P., Zimmermann, F. M., Witt, N., Berry, C., Jeremias, A., Koo, B.-K., Esposito, G., Rioufol, G., Park, S.-J., Nishi, T., Choi, D.-H., Oldroyd, K. G., Barbato, E., Pijls, N. H. J., De Bruyne, B., Fearon, W. F. (2017) Agreement of the resting distal to aortic coronary pressure with the instantaneous wave-free ratio. Journal of the American College of Cardiology, 70, pp. 2105-2113. (doi: 10.1016/j.jacc.2017.08.049)

Lemonidis, K., MacLeod, R., Baillie, G. S., Chamberlain, L. H. (2017) Peptide array based screening reveals a large number of proteins interacting with the ankyrin repeat domain of the zDHHC17 S-acyltransferase. Journal of Biological Chemistry, 292, pp. 17190-17202. (doi: 10.1074/jbc.M117.799650)

Gao, H., Mangion, K., Carrick, D., Husmeier, D., Luo, X., Berry, C. (2017) Estimating prognosis in patients with acute myocardial infarction using personalized computational heart models. Scientific Reports, 7, (doi: 10.1038/s41598-017-13635-2)

Petrushanko, I. Y., Mitkevich, V. A., Lakunina, V. A., Anashkina, A. A., Spirin, P. V., Rubtsov, P. M., Prassolov, V. S., Bogdanov, N. B., Hänggi, P., Fuller, W., Makarov, A. A., Bogdanova, A. (2017) Cysteine residues 244 and 458–459 within the catalytic subunit of Na,K-ATPase control the enzyme's hydrolytic and signaling function under hypoxic conditions. Redox Biology, 13, pp. 310-319. (doi: 10.1016/j.redox.2017.05.021)

Nishi, T., Johnson, N. P., De Bruyne, B., Berry, C., Gould, K. L., Jeremias, A., Oldroyd, K. G., Kobayashi, Y., Choi, D.-H., Pijls, N. H.J., Fearon, W. F. (2017) Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve. Circulation: Cardiovascular Interventions, 10, (doi: 10.1161/CIRCINTERVENTIONS.117.004985)

Gao, H., Qi, N., Feng, L., Ma, X., Danton, M., Berry, C., Luo, X. (2017) Modelling mitral valvular dynamics–current trend and future directions. International Journal for Numerical Methods in Biomedical Engineering, 33, (doi: 10.1002/cnm.2858)

Gao, H., Feng, L., Qi, N., Berry, C., Griffith, B. E., Luo, X. (2017) A coupled mitral valve - left ventricle model with fluid-structure interaction. Medical Engineering and Physics, 47, pp. 128-136. (doi: 10.1016/j.medengphy.2017.06.042)

Sliwa, K., Mebazaa, A., Hilfiker-Kleiner, D., Petrie, M. C., Maggioni, A. P., Laroche, C., Regitz-Zagrosek, V., Schaufelberger, M., Tavazzi, L., van der Meer, P., Roos-Hesselink, J. W., Seferovic, P., van Spandonck-Zwarts, K., Mbakwem, A., Böhm, M., Mouquet, F., Pieske, B., Hall, R., Ponikowski, P., Bauersachs, J. (2017) Clinical characteristics of patients from the worldwide registry on peripartum cardiomyopathy (PPCM) European Journal of Heart Failure, 19, pp. 1131-1141. (doi: 10.1002/ejhf.780)

Murphy, S. R., Wang, L., Wang, Z., Domondon, P., Lang, D., Habecker, B. A., Myles, R. C., Ripplinger, C. M. (2017) β-adrenergic inhibition prevents action potential and calcium handling changes during regional myocardial ischemia. Frontiers in Physiology, 8, (doi: 10.3389/fphys.2017.00630)

Berry, C. (2017) Stable coronary syndromes: the case for consolidating the nomenclature of stable ischemic heart disease. Circulation, 136, pp. 437-439. (doi: 10.1161/CIRCULATIONAHA.117.028991)

Newby, D. et al. (2017) Aortic wall inflammation predicts abdominal aortic aneurysm expansion, rupture, and need for surgical repair. Circulation, 136, pp. 787-797. (doi: 10.1161/CIRCULATIONAHA.117.028433)

Mangion, K., McComb, C., Auger, D. A., Epstein, F. H., Berry, C. (2017) Magnetic resonance imaging of myocardial strain after acute ST-segment-elevation myocardial infarction: a systematic review. Circulation: Cardiovascular Imaging, 10, (doi: 10.1161/CIRCIMAGING.117.006498)

Shen, L., Jhund, P. S., Petrie, M. C., Claggett, B. L., Barlera, S., Cleland, J. G.F., Dargie, H. J., Granger, C. B., Kjekshus, J., Køber, L., Latini, R., Maggioni, A. P., Packer, M., Pitt, B., Solomon, S. D., Swedberg, K., Tavazzi, L., Wikstrand, J., Zannad, F., Zile, M. R., McMurray, J. J.V. (2017) Declining risk of sudden death in heart failure. New England Journal of Medicine, 377, pp. 41-51. (doi: 10.1056/NEJMoa1609758)

Ford, T. J., Corcoran, D., Berry, C. (2017) Coronary artery disease: physiology and prognosis. European Heart Journal, 38, pp. 1990-1992. (doi: 10.1093/eurheartj/ehx226)

Nishi, K., Luo, H., Ishikura, S., Doi, K., Iwaihara, Y., Wills, L., Baillie, G. S., Sakata, T., Shirasawa, S., Tsunoda, T. (2017) Apremilast induces apoptosis of human colorectal cancer cells with mutant KRAS. Anticancer Research, 37, pp. 3833-3839. (doi: 10.21873/anticanres.11762)

Gao, H., Aderhold, A., Mangion, K., Luo, X., Husmeier, D., Berry, C. (2017) Changes and classification in myocardial contractile function in the left ventricle following acute myocardial infarction. Journal of the Royal Society: Interface, 14, (doi: 10.1098/rsif.2017.0203)

Corcoran, D., Hennigan, B., Berry, C. (2017) Fractional flow reserve: a clinical perspective. International Journal of Cardiovascular Imaging, 33, pp. 961-974. (doi: 10.1007/s10554-017-1159-2)

Kiely, M., Adams, D. R., Hayes, S. L., O'Connor, R., Baillie, G. S., Kiely, P. A. (2017) RACK1 stabilises the activity of PP2A to regulate the transformed phenotype in mammary epithelial cells. Cellular Signalling, 35, pp. 290-300. (doi: 10.1016/j.cellsig.2016.09.001)

Williams, M. C., Hunter, A., Shah, A., Assi, V., Lewis, S., Mangion, K., Berry, C., Boon, N. A., Clark, E., Flather, M., Forbes, J., McLean, S., Roditi, G., van Beek, E. J.R., Timmis, A. D., Newby, D. E. (2017) Symptoms and quality of life in patients with suspected angina undergoing CT coronary angiography: a randomised controlled trial. Heart, 103, pp. 995-1001. (doi: 10.1136/heartjnl-2016-310129)

Cleland, J. G.F., Pellicori, P., Clark, A. L., Petrie, M. C. (2017) Time to take the failure out of heart failure: the importance of optimism. JACC: Heart Failure, 5, pp. 538-540. (doi: 10.1016/j.jchf.2017.04.003)

Hennigan, B., Johnson, N., McClure, J., Corcoran, D., Watkins, S., Berry, C., Oldroyd, K. G. (2017) Validation of the "smart" minimum FFR Algorithm in an unselected all comer population of patients with intermediate coronary stenoses. International Journal of Cardiovascular Imaging, 33, pp. 991-997. (doi: 10.1007/s10554-017-1126-y)

Plain, F., Congreve, S. D., Yee, R. S. Z., Kennedy, J., Howie, J., Kuo, C.-W., Fraser, N. J., Fuller, W. (2017) An amphipathic α-helix directs palmitoylation of the large intracellular loop of the sodium/calcium exchanger. Journal of Biological Chemistry, 292, pp. 10745-10752. (doi: 10.1074/jbc.M116.773945)

Aetesam-ur-Rahman, M., Berry, C. (2017) Cardiovascular Diagnosis and Therapy (CDT) editorial: the Minimalist Immediate Mechanical Intervention study. Cardiovascular Diagnosis and Therapy, 7, pp. S73-S76. (doi: 10.21037/cdt.2017.01.13)

Sattar, N., Petrie, M. C., Zinman, B., Januzzi Jr., J. L. (2017) Novel diabetes drugs and the cardiovascular specialist. Journal of the American College of Cardiology, 69, pp. 2646-2656. (doi: 10.1016/j.jacc.2017.04.014)

Packer, M., O'Connor, C., McMurray, J. J.V., Wittes, J., Abraham, W. T., Anker, S. D., Dickstein, K., Filippatos, G., Holcomb, R., Krum, H., Maggioni, A. P., Mebazaa, A., Peacock, W. F., Petrie, M. C., Ponikowski, P., Ruschitzka, F., van Veldhuisen, D. J., Kowarski, L. S., Schactman, M., Holzmeister, J. (2017) Effect of ularitide on cardiovascular mortality in acute heart failure. New England Journal of Medicine, 376, pp. 1956-1964. (doi: 10.1056/NEJMoa1601895)

Ibáñez de Opakua, A., Parag-Sharma, K., DiGiacomo, V., Merino, N., Leyme, A., Marivin, A., Villate, M., Nguyen, L. T., de la Cruz-Morcillo, M. A., Blanco-Canosa, J. B., Ramachandran, S., Baillie, G. S., Cerione, R. A., Blanco, F. J., Garcia-Marcos, M. (2017) Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif. Nature Communications, 8, (doi: 10.1038/ncomms15163)

Diamantopoulou, Z., White, G., Fadlullah, M. Z.H., Dreger, M., Pickering, K., Maltas, J., Ashton, G., MacLeod, R., Baillie, G. S., Kouskoff, V., Lacaud, G., Murray, G. I., Sansom, O. J., Hurlstone, A. F.L., Malliri, A. (2017) TIAM1 antagonizes TAZ/YAP both in the destruction complex in the cytoplasm and in the nucleus to inhibit invasion of intestinal epithelial cells. Cancer Cell, 31, pp. 621-634. (doi: 10.1016/j.ccell.2017.03.007)

Monterisi, S., Lobo, M. J., Livie, C., Castle, J. C., Weinberger, M., Baillie, G., Surdo, N. C., Musheshe, N., Stangherlin, A., Gottlieb, E., Maizels, R., Bortolozzi, M., Micaroni, M., Zaccolo, M. (2017) PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling. eLife, 6, (doi: 10.7554/eLife.21374)

Packer, M. et al. (2017) Long-term effect of endothelin receptor antagonism with bosentan on the morbidity and mortality of patients with severe chronic heart failure : primary results of the ENABLE Trials. JACC: Heart Failure, 5, pp. 317-326. (doi: 10.1016/j.jchf.2017.02.021)

Singh, A., Greenwood, J. P., Berry, C., Dawson, D. K., Hogrefe, K., Kelly, D. J., Dhakshinamurthy, V., Lang, C. C.,, Khoo, J. P., Sprigings, D., Steeds, R. P., Jerosch-Herold, M., Neubauer, S., Prendergast, B., Williams, B., Zhang, R., Hudson, I., Squire, I. B., Ford, I., Samani, N. J., McCann, G. P. (2017) Comparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) study. European Heart Journal, 38, pp. 1222-1229. (doi: 10.1093/eurheartj/ehx001)

Layland, J., Rauhalammi, S., Lee, M. M.Y., Ahmed, N., Carberry, J., Teng Yue May, V., Watkins, S., McComb, C., Mangion, K., McClure, J. D., Carrick, D., O'Donnell, A., Sood, A., McEntegart, M., Oldroyd, K. G., Radjenovic, A., Berry, C. (2017) Diagnostic accuracy of 3.0-T magnetic resonance T1 and T2 mapping and T2-weighted dark-blood imaging for the infarct-related coronary artery in Non-ST-segment elevation myocardial infarction. Journal of the American Heart Association, 6, (doi: 10.1161/JAHA.116.004759)

Wilson, S. J., Newby, D. E., Dawson, D., Irving, J., Berry, C. (2017) Duration of dual antiplatelet therapy in acute coronary syndrome. Heart, 103, pp. 573-580. (doi: 10.1136/heartjnl-2016-309871)

Schoenherr, C., Byron, A., Sandilands, E., Paliashvili, K., Baillie, G. S., Valacca, C., Cecconi, F., Serrels, B., Frame, M. C. (2017) Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks. eLife, 6, (doi: 10.7554/eLife.23172)

Layland, J. J., Carberry, J., May, V. T.Y., Lee, M., Eteiba, H., Lindsay, M., Petrie, M., McEntegart, M., Watkins, S., Shaukat, A., Oldroyd, K., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Hannah, A., Stewart, A., Henderson, R., McConnachie, A., Berry, C. (2017) Decision Making Using Fractional Flow Reserve is Associated With Lower Rates of Incomplete Revascularization Compared With Angiographic Guided Decision Making Amongst Patients With NSTEMI. (doi: 10.1016/s0735-1097(17)34446-7)

Graham-Brown, M. P.M., Rutherford, E., Levelt, E., March, D. S., Churchward, D. R., Stensel, D. J., McComb, C., Mangion, K., Cockburn, S., Berry, C., Moon, J. C., Mark, P. B., Burton, J. O., McCann, G. P. (2017) Native T1 mapping: inter-study, inter-observer and inter-center reproducibility in hemodialysis patients. Journal of Cardiovascular Magnetic Resonance, 19, (doi: 10.1186/s12968-017-0337-7)

Houslay, K. F., Christian, F., MacLeod, R., Adams, D. R., Houslay, M. D., Baillie, G. S. (2017) Identification of a multifunctional docking site on the catalytic unit of phosphodiesterase-4 (PDE4) that is utilised by multiple interaction partners. Biochemical Journal, 474, pp. 597-609. (doi: 10.1042/BCJ20160849)

Docherty, K. F., Campbell, R. T., Jhund, P., Petrie, M. C., McMurray, J. J.V. (2017) How robust are clinical trials in heart failure? European Heart Journal, 38, pp. 338-345. (doi: 10.1093/eurheartj/ehw427)

Deschamps, T., Quentin, B., Leske, D. M., MacLeod, R., Mompelat, D., Tafforeau, L., Lotteau, V., Maréchal, V., Baillie, G. S., Gruffat, H., Wilson, J. B., Manet, E. (2017) Epstein-Barr virus nuclear antigen 1 interacts with regulator of chromosome condensation 1 dynamically throughout the cell cycle. Journal of General Virology, 98, pp. 251-265. (doi: 10.1099/jgv.0.000681)

Hurst, C. H., Turnbull, D., Plain, F., Fuller, W., Hemsley, P. A. (2017) Maleimide scavenging enhances determination of protein S-palmitoylation state in acyl-exchange methods. BioTechniques, 62, pp. 69-75. (doi: 10.2144/000114516)

Wetzel, C., Pifferi, S., Picci, C., Gök, C., Hoffmann, D., Bali, K. K., Lampe, A., Lapatsina, L., Fleischer, R., Smith, E. S. J., Bégay, V., Moroni, M., Estebanez, L., Kühnemund, J., Walcher, J., Specker, E., Neuenschwander, M., von Kries, J. P., Haucke, V., Kuner, R., Poulet, J. F. A., Schmoranzer, J., Poole, K., Lewin, G. R. (2017) Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity. Nature Neuroscience, 20, pp. 209-218. (doi: 10.1038/nn.4454)

Gebhard, C., Rhéaume, E., Berry, C., Brand, G., Kernaleguen, A.-E., Théberge-Julien, G., Alam, M. A., Lee, C. Y.W., Boileau, L., Chabot-Blanchet, M., Guertin, M.-C., Lavoie, M.-A., Grégoire, J., Ibrahim, R., L'Allier, P., Tardif, J.-C. (2017) Beneficial effects of reconstituted high-density lipoprotein (rHDL) on circulating CD34+ cells in patients after an acute coronary syndrome. PLoS ONE, 12, (doi: 10.1371/journal.pone.0168448)

Kristensen, S. L., Mogensen, U. M., Jhund, P. S., Petrie, M. C., Preiss, D., Win, S., Køber, L., McKelvie, R. S., Zile, M. R., Anand, I. S., Komajda, M., Gottdiener, J. S., Carson, P. E., McMurray, J. J.V. (2017) Clinical and echocardiographic characteristics and cardiovascular outcomes according to diabetes status in patients with heart failure and preserved ejection fraction. A report from the Irbesartan in Heart Failure with Preserved Ejection Fraction Trial (I-Preserve) Circulation, 135, pp. 724-735. (doi: 10.1161/CIRCULATIONAHA.116.024593)

Cameron, R. T., Whiteley, E., Day, J. P., Parachikova, A. I., Baillie, G. S. (2017) Selective inhibition of phosphodiesterases 4, 5 and 9 induces HSP20 phosphorylation and attenuates amyloid beta 1-42 mediated cytotoxicity. FEBS Open Bio, 7, pp. 64-73. (doi: 10.1002/2211-5463.12156)

Javadi, A., Deevi, R. K., Evergren, E., Blondel-Tepaz, E., Baillie, G. S., Scott, M. G.H., Campbell, F. C. (2017) PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex. eLife, 6, (doi: 10.7554/eLife.24578)

Plain, F., Turnbull, D., Fraser, N. J., Fuller, W. (2017) Understanding the rules governing NCX1 palmitoylation. Channels, 11, pp. 377-379. (doi: 10.1080/19336950.2017.1342501)

2016

Mangion, K., Gao, H., Mccomb, C., Carrick, D., Clerfond, G., Zhong, X., Luo, X., Haig, C., Berry, C. (2016) A novel method for estimating myocardial strain: assessment of deformation tracking against reference magnetic resonance methods in healthy volunteers. Scientific Reports, 6, (doi: 10.1038/srep38774)

Huethorst, E., Hortigon, M., Zamora-Rodriguez, V., Reynolds, P.M., Burton, F., Smith, G., Gadegaard, N. (2016) Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate. ACS Biomaterials Science and Engineering, 2, pp. 2231-2239. (doi: 10.1021/acsbiomaterials.6b00426)

Kobayashi, Y., Johnson, N. P., Berry, C., De Bruyne, B., Gould, K. L., Jeremias, A., Oldroyd, K. G., Pijls, N. H.J., Fearon, W. F. (2016) The influence of lesion location on the diagnostic accuracy of adenosine-free coronary pressure wire measurements. JACC: Cardiovascular Interventions, 9, pp. 2390-2399. (doi: 10.1016/j.jcin.2016.08.041)

Carrick, D., Haig, C., Ahmed, N., Carberry, J., Teng Yue May, V., McEntegart, M., Petrie, M. C., Eteiba, H., Lindsay, M., Hood, S., Watkins, S., Davies, A., Abouzaid, A. M., Mordi, I., Ford, I., Radjenovic, A., Oldroyd, K. G., Berry, C. (2016) Comparative prognostic utility of indexes of microvascular function alone or in combination in patients with an acute ST-segment elevation myocardial infarction. Circulation, 134, pp. 1833-1847. (doi: 10.1161/CIRCULATIONAHA.116.022603)

Nagaraja, V., Ooi, S.-Y., Nolan, J., Large, A., De Belder, M., Ludman, P., Bagur, R., Curzen, N., Matsukage, T., Yoshimachi, F., Kwok, C. S., Berry, C., Mamas, M. A. (2016) Impact of incomplete percutaneous revascularization in patients With multivessel coronary artery disease: a systematic review and meta-analysis. Journal of the American Heart Association, 5, (doi: 10.1161/JAHA.116.004598)

Kaye, D. M., Hasenfuß, G., Neuzil, P., Post, M. C., Doughty, R., Trochu, J.-N., Kolodziej, A., Westenfeld, R., Penicka, M., Rosenberg, M., Walton, A., Muller, D., Walters, D., Hausleiter, J., Raake, P., Petrie, M. C., Bergmann, M., Jondeau, G., Feldman, T., van Veldhuisen, D. J., Ponikowski, P., Silvestry, F. E., Burkhoff, D., Hayward, C. (2016) One-year outcomes after transcatheter insertion of an interatrial shunt device for the management of heart failure with preserved ejection fraction. Circulation: Heart Failure, 9, (doi: 10.1161/CIRCHEARTFAILURE.116.003662)

Hortigon-Vinagre, M.P., Zamora, V., Burton, F.L., Green, J., Gintant, G.A., Smith, G.L. (2016) The use of ratiometric fluorescence measurements of the voltage sensitive dye Di-4-ANEPPS to examine action potential characteristics and drug effects on human induced pluripotent stem cell-derived cardiomyocytes. Toxicological Sciences, 154, pp. 320-331. (doi: 10.1093/toxsci/kfw171)

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Baillie, G. S. (2016) Editorial. Cellular Signalling, 28, pp. 699-700. (doi: 10.1016/j.cellsig.2016.02.001)

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Corcoran, D., Berry, C. (2016) How to measure myocardial infarct size by cardiac magnetic resonance imaging. Heart and Metabolism, 70, pp. 14-18.

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Baeza-Raja, B., Sachs, B. D., Li, P., Christian, F., Vagena, E., Davalos, D., Le Moan, N., Ryu, J. K., Sikorski, S. L., Chan, J. P., Scadeng, M., Taylor, S. S., Houslay, M. D., Baillie, G. S., Saltiel, A. R., Olefsky, J. M., Akassoglou, K. (2016) p75 neurotrophin receptor regulates energy balance in obesity. Cell Reports, 14, pp. 255-268. (doi: 10.1016/j.celrep.2015.12.028)

2015

Berry, C., Corcoran, D., Hennigan, B., Watkins, S., Layland, J., Oldroyd, K. G. (2015) Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent developments. European Heart Journal, 36, pp. 3155-3164. (doi: 10.1093/eurheartj/ehv206)

Nam, J., Briggs, A., Layland, J., Oldroyd, K. G., Curzen, N., Sood, A., Balachandran, K., Das, R., Junejo, S., Eteiba, H., Petrie, M. C., Lindsay, M., Watkins, S., Corbett, S., O'Rourke, B., O'Donnell, A., Stewart, A., Hannah, A., McConnachie, A., Henderson, R., Berry, C. (2015) Fractional flow reserve (FFR) versus angiography in guiding management to optimise outcomes in non-ST segment elevation myocardial infarction (FAMOUS-NSTEMI) developmental trial: cost-effectiveness using a mixed trial- and model-based methods. Cost Effectiveness and Resource Allocation, 2015, (doi: 10.1186/s12962-015-0045-9)

Gao, H., Li, W.G., Cai, L., Berry, C., Luo, X.Y. (2015) Parameter estimation in a Holzapfel–Ogden law for healthy myocardium. Journal of Engineering Mathematics, 95, pp. 231-248. (doi: 10.1007/s10665-014-9740-3)

Zinman, B., Wanner, C., Lachin, J. M., Fitchett, D., Bluhmki, E., Hantel, S., Mattheus, M., Devins, T., Johansen, O. E., Woerle, H. J., Broedl, U. C., Inzucchi, S. E., EMPA-REG OUTCOME Investigators, (2015) Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. New England Journal of Medicine, 373, pp. 2117-2128. (doi: 10.1056/NEJMoa1504720)

Layland, J., Nerlekar, N., Palmer, S., Berry, C., Oldroyd, K. (2015) Invasive assessment of the coronary microcirculation in the catheter laboratory. International Journal of Cardiology, 199, pp. 141-149. (doi: 10.1016/j.ijcard.2015.05.190)

Jolicœur, E. M., Dunning, A., Castelvecchio, S., Dabrowski, R., Waclawiw, M. A., Petrie, M. C., Stewart, R., Jhund, P. S., Desvigne-Nickens, P., Panza, J. A., Bonow, R. O., Sun, B., San, T. R., Al-Khalidi, H. R., Rouleau, J. L., Velazquez, E. J., Cleland, J. G.F. (2015) Importance of angina in patients with coronary disease, heart failure, and left ventricular systolic dysfunction. Journal of the American College of Cardiology, 66, pp. 2092-2100. (doi: 10.1016/j.jacc.2015.08.882)

Aitken, E., Kerr, D., Geddes, C., Berry, C., Kingsmore, D. (2015) Cardiovascular changes occurring with occlusion of a mature arteriovenous fistula. Journal of Vascular Access, 16, pp. 459-466. (doi: 10.5301/jva.5000336)

Baillie, G. S. (2015) George Baillie on peptide array, a technique that transformed research on phosphodiesterases. Future Science OA, 1, (doi: 10.4155/fso.15.25)

Simpson, J., Castagno, D., Doughty, R. N., Poppe, K. K., Earle, N., Squire, I., Richards, M., Andersson, B., Ezekowitz, J. A., Komajda, M., Petrie, M. C., McAlister, F. A., Gamble, G. D., Whalley, G. A., McMurray, J. J.V. (2015) Is heart rate a risk marker in patients with chronic heart failure and concomitant atrial fibrillation? Results from the MAGGIC meta-analysis. European Journal of Heart Failure, 17, pp. 1182-1191. (doi: 10.1002/ejhf.346)

Reilly, L., Howie, J., Wypijewski, K., Ashford, M. L. J., Hilgemann, D. W., Fuller, W. (2015) Palmitoylation of the Na/Ca exchanger cytoplasmic loop controls its inactivation and internalization during stress signaling. FASEB Journal, 29, pp. 4532-4543. (doi: 10.1096/fj.15-276493)

MacLeod, R., Hillert, E.-K., Cameron, R. T., Baillie, G. S. (2015) The role and therapeutic targeting of α-, β- and γ-secretase in Alzheimer's disease. Future Science OA, 1, (doi: 10.4155/fso.15.9)

Sin, Y. Y., Baillie, G. (2015) Heat Shock Protein 20 (HSP20) is a novel substrate for Protein Kinase D1 (PKD1) Cell Biochemistry and Function, 33, pp. 421-426. (doi: 10.1002/cbf.3147)

Zoccarato, A. et al. (2015) Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research, 117, pp. 707-719. (doi: 10.1161/CIRCRESAHA.114.305892)

Corcoran, D., Grant, P., Berry, C. (2015) Risk stratification in non-ST elevation acute coronary syndromes: risk scores, biomarkers and clinical judgment. International Journal of Cardiology: Heart and Vasculature, 8, pp. 131-137. (doi: 10.1016/j.ijcha.2015.06.009)

Fisher, M., Petrie, M., Ambery, P., Donaldson, J., McMurray, J. J.V., Ye, J. (2015) Cardiovascular safety of albiglutide in the Harmony programme: a meta-analysis. Lancet Diabetes and Endocrinology, 3, pp. 697-703. (doi: 10.1016/s2213-8587(15)00233-8)

Eykyn, T. R., Aksentijević, D., Aughton, K. L., Southworth, R., Fuller, W., Shattock, M. J. (2015) Multiple quantum filtered 23Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlates with [Na]i. Journal of Molecular and Cellular Cardiology, 86, pp. 95-101. (doi: 10.1016/j.yjmcc.2015.07.009)

Mordi, I., Radjenovic, A., Stanton, T., Gardner, R., McPhaden, A., Carrick, D., Berry, C., Tzemos, N. (2015) Prevalence and prognostic significance of lipomatous metaplasia in poatients with prior myocardial infarction. JACC: Cardiovascular Imaging, 8, pp. 1111-1112. (doi: 10.1016/j.jcmg.2014.07.024)

McComb, C., Carrick, D., McClure, J. D., Woodward, R., Radjenovic, A., Foster, J. E., Berry, C. (2015) Assessment of the relationships between myocardial contractility and infarct tissue revealed by serial magnetic resonance imaging in patients with acute myocardial infarction. International Journal of Cardiovascular Imaging, 31, pp. 1201-1209. (doi: 10.1007/s10554-015-0678-y)

Jackson, C. E., Haig, C., Welsh, P., Dalzell, J. R., Tsorlalis, I. K., McConnachie, A., Preiss, D., McInnes, I. B., Sattar, N., Petrie, M. C., Gardner, R. S., McMurray, J. J.V. (2015) Combined free light chains are novel predictors of prognosis in heart failure. JACC: Heart Failure, 3, pp. 618-625. (doi: 10.1016/j.jchf.2015.03.014)

Rush, C. J., Campbell, R. T., Jhund, P. S., Connolly, E. C., Preiss, D., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Falling cardiovascular mortality in heart failure with reduced ejection fraction and implications for clinical trials. JACC: Heart Failure, 3, pp. 603-614. (doi: 10.1016/j.jchf.2015.03.013)

Garg, S., Anderson, S.G., Oldroyd, K., Berry, C., Emdin, C.A., Peters, S.A.E., West, N.E.J., Kelly, D., Balachandran, K., McDonald, J., Singh, R., Devadathan, S., Redwood, S., Ludman, P.F., Rahimi, K., Woodward, M. (2015) Outcomes of percutaneous coronary intervention performed at offsite versus onsite surgical centers in the United Kingdom. Journal of the American College of Cardiology, 66, pp. 363-372. (doi: 10.1016/j.jacc.2015.05.052)

Mckinney, C.A., Kennedy, S., Baillie, G.S., Milligan, G., Nicklin, S.A. (2015) Angiotensin-(1-7) and angiotensin-(1-9) inhibit vascular smooth muscle cell growth and migration in vitro and vascular remodelling in vivo. Atherosclerosis, 241, pp. e44. (doi: 10.1016/j.atherosclerosis.2015.04.158)

MacDonald, M. R., She, L., Doenst, T., Binkley, P. F., Rouleau, J. L., Tan, R.-S., Lee, K. L., Miller, A. B., Sopko, G., Szalewska, D., Waclawiw, M. A., Dabrowski, R., Castelvecchio, S., Adlbrecht, C., Michler, R. E., Oh, J. K., Velazquez, E. J., Petrie, M. C. (2015) Clinical characteristics and outcomes of patients with and without diabetes in the Surgical Treatment for Ischemic Heart Failure (STICH) trial. European Journal of Heart Failure, 17, pp. 725-734. (doi: 10.1002/ejhf.288)

Zarros, A., Cameron, R.T., Bimpis, A., Baillie, G.S. (2015) Exposure of mHIPPOE-14 cells to oligomycin as a tool for in vitro approaches to brain ischaemia-related pro- and epiphenomena: time-dependent cellular response profiling. Atherosclerosis, 241, pp. e221. (doi: 10.1016/j.atherosclerosis.2015.04.1038)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Lindsay, M., Watkins, S., Hood, S., Davie, A., Marous, A., Sattar, N., Welsh, P., Tzemos, N., Radjenovic, A., Ford, I., Oldroyd, K., Berry, C. (2015) Pathophysiology of LV remodeling in survivors of STEMI : inflammation, remote myocardium, and prognosis. JACC: Cardiovascular Imaging, 8, pp. 779-789. (doi: 10.1016/j.jcmg.2015.03.007)

Parnell, E., Koschinski, A., Zaccolo, M., Cameron, R. T., Baillie, G. S., Baillie, G. L., Porter, A., McElroy, S. P., Yarwood, S. J. (2015) Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells. Biochimica et Biophysica Acta: Molecular Cell Research, 1853, pp. 1749-1758. (doi: 10.1016/j.bbamcr.2015.04.009)

Johnson, N.P., Johnson, D.T., Kirkeeide, R.L., Berry, C., De Bruyne, B., Fearon, W.F., Oldroyd, K.G., Pijls, N.H.J., Gould, K.L. (2015) Repeatability of fractional flow reserve despite variations in systemic and coronary hemodynamics. JACC: Cardiovascular Interventions, 8, pp. 1018-1027. (doi: 10.1016/j.jcin.2015.01.039)

Petrie, M.C., Boyle, J.G., McKay, G.A. (2015) Use of metformin in chronic kidney disease should continue to be based on common sense in the absence of an evidence base. Diabetic Medicine, 32, pp. 981-982. (doi: 10.1111/dme.12709)

Hu, D. et al. (2015) Artery tertiary lymphoid organs control aorta immunity and protect against atherosclerosis via vascular smooth muscle cell lymphotoxin β receptors. Immunity, 42, pp. 1100-1115. (doi: 10.1016/j.immuni.2015.05.015)

Al Halabi, S., Qintar, M., Hussein, A., Alraies, M. C., Jones, D. G., Wong, T., MacDonald, M. R., Petrie, M. C., Cantillon, D., Tarakji, K. G., Kanj, M., Bhargava, M., Varma, N., Baranowski, B., Wilkoff, B. L., Wazni, O., Callahan, T., Saliba, W., Chung, M. K. (2015) Catheter ablation for atrial fibrillation in heart failure patients. JACC: Clinical Electrophysiology, 1, pp. 200-209. (doi: 10.1016/j.jacep.2015.02.018)

Dalzell, J. R., Rocchiccioli, J. P., Weir, R. A.P., Jackson, C. E., Padmanabhan, N., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) The emerging potential of the apelin-APJ system in heart failure. Journal of Cardiac Failure, 21, pp. 489-498. (doi: 10.1016/j.cardfail.2015.03.007)

Kukulski, T., She, L., Racine, N., Gradinac, S., Panza, J. A., Velazquez, E. J., Chan, K., Petrie, M. C., Lee, K. L., Pellikka, P. A., Romanov, A., Biernat, J., Rouleau, J. L., Batlle, C., Rogowski, J., Ferrazzi, P., Zembala, M., Oh, J. K. (2015) Implication of right ventricular dysfunction on long-term outcome in patients with ischemic cardiomyopathy undergoing coronary artery bypass grafting with or without surgical ventricular reconstruction. Journal of Thoracic and Cardiovascular Surgery, 149, pp. 1312-1321. (doi: 10.1016/j.jtcvs.2014.09.117)

Wang, L., Burmeister, B. T., Johnson, K. R., Baillie, G. S., Karginov, A. V., Skidgel, R. A., O'Bryan, J. P., Carnegie, G. K. (2015) UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy. Cellular Signalling, 27, pp. 908-922. (doi: 10.1016/j.cellsig.2015.02.003)

Bolger, G. B., Dunlop, A. J., Meng, D., Day, J. P., Klussmann, E., Baillie, G. S., Adams, D. R., Houslay, M. D. (2015) Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains. Cellular Signalling, 27, pp. 756-769. (doi: 10.1016/j.cellsig.2014.12.009)

Myles, R. C., Wang, L., Bers, D. M., Ripplinger, C. M. (2015) Decreased inward rectifying K+current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart. Journal of Physiology, 593, pp. 1479-1493. (doi: 10.1113/jphysiol.2014.279638)

Sin, Y. Y., Martin, T. P., Wills, L., Currie, S., Baillie, G. S. (2015) Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy. Cell Communication and Signaling, 13, (doi: 10.1186/s12964-015-0094-x)

Wypijewski, K. J., Tinti, M., Chen, W., Lamont, D., Ashford, M. L. J., Calaghan, S. C., Fuller, W. (2015) Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation. Molecular and Cellular Proteomics, 14, pp. 596-608. (doi: 10.1074/mcp.M114.038570)

Campbell, R. T., Jackson, C., Wright, A., Gardner, R. S., Ford, I., Davidson, P. M., Denvir, M. A., Hogg, K. J., Johnson, M. J., Petrie, M. C., McMurray, J. J. V. (2015) Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design. ESC Heart Failure, 2, pp. 25-36. (doi: 10.1002/ehf2.12027)

Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Brunton, A. P.T., Jhund, P. S., Wong, C. M., Solomon, S. D., Granger, C. B., Yusuf, S., Pfeffer, M. A., Swedberg, K., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with angina and heart failure in the CHARM (Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity) programme. European Journal of Heart Failure, 17, pp. 196-204. (doi: 10.1002/ejhf.221)

Zarros, A., Johnson, S. A., Mackenzie-Gray Scott, C. A., Baillie, G. S. (2015) Cytodynamics and endpoint selection for a reliable in vitro assessment of nanoneurotoxicity. Nanomedicine: Nanotechnology, Biology and Medicine, 11, pp. 407-408. (doi: 10.1016/j.nano.2014.08.014)

Alday, E. A. P., Colman, M. A., Langley, P., Butters, T. D., Higham, J., Workman, A. J., Hancox, J. C., Zhang, H. (2015) A new algorithm to diagnose atrial ectopic origin from multi lead ECG systems: insights from 3D virtual human atria and torso. PLoS Computational Biology, 11, pp. e1004026. (doi: 10.1371/journal.pcbi.1004026)

Layland, J. et al. (2015) Fractional flow reserve vs. angiography in guiding management to optimize outcomes in non-ST-segment elevation myocardial infarction: the British Heart Foundation FAMOUS-NSTEMI randomized trial. European Heart Journal, 36, pp. 100-111. (doi: 10.1093/eurheartj/ehu338)

Ghouri, I. A., Kelly, A., Burton, F. L., Smith, G. L., Kemi, O. J. (2015) 2-photon excitation fluorescence microscopy enables deeper high-resolution imaging of voltage and Ca2+in intact mice, rat, and rabbit hearts. Journal of Biophotonics, 8, pp. 112-123. (doi: 10.1002/jbio.201300109)

Ripley, D. P., Brown, J., Everett, C. C., Bijsterveld, P., Walker, S., Sculpher, M., McCann, G. P., Berry, C., Plein, S., Greenwood, J. P. (2015) Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease. American Heart Journal, 169, pp. 17-24.e1. (doi: 10.1016/j.ahj.2014.10.008)

Kalafatakis, K., Gkanti, V., Mackenzie-Gray Scott, C. A., Zarros, A., Baillie, G. S., Tsakiris, S. (2015) Acetylcholinesterase activity as a neurotoxicity marker within the context of experimentally-simulated hyperprolinaemia: an in vitro approach. Journal of Natural Science, Biology and Medicine, 6, pp. 98-101. (doi: 10.4103/0976-9668.166099)

Layland, J., Rauhalammi, S., Watkins, S., Ahmed, N., McClure, J., Lee, M. M.Y., Carrick, D., O’Donnell, A., Sood, A., Petrie, M. C., Teng Yue May, V., Eteiba, H., Lindsay, M., McEntegart, M., Oldroyd, K. G., Radjenovic, A., Berry, C. (2015) Assessment of fractional flow reserve in patients with recent Non–ST-Segment–Elevation Myocardial Infarction. Circulation: Cardiovascular Interventions, 8, (doi: 10.1161/circinterventions.114.002207)

Newby, D. et al. (2015) CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial. Lancet, 385, pp. 2383-2391. (doi: 10.1016/S0140-6736(15)60291-4)

Badar, A. A., Perez-Moreno, A. C., Hawkins, N. M., Jhund, P. S., Brunton, A. P.T., Anand, I. S., McKelvie, R. S., Komajda, M., Zile, M. R., Carson, P. E., Gardner, R. S., Petrie, M. C., McMurray, J. J.V. (2015) Clinical characteristics and outcomes of patients with coronary artery disease and angina. Circulation: Heart Failure, 8, pp. 717-724. (doi: 10.1161/CIRCHEARTFAILURE.114.002024)

Corcoran, D., Berry, C., Oldroyd, K. (2015) Current frontiers in the clinical research of coronary physiology. Interventional Cardiology, 7, pp. 97-106.

Gao, H., Qi, N., Ma, X., Griffith, B. E., Berry, C., Luo, X. (2015) Fluid-structure interaction model of human mitral valve within left ventricle. Springer International Publishing

Bottcher, R., Henderson, D. J. P., Dulla, K., van Strijp, D., Waanders, L. F., Tevz, G., Lehman, M. L., Merkle, D., van Leenders, G. J. L. H., Baillie, G. S., Jenster, G., Houslay, M. D., Hoffmann, R. (2015) Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression. British Journal of Cancer, 113, pp. 1502-1511. (doi: 10.1038/bjc.2015.335)

Gao, H., Berry, C., Luo, X. (2015) Image-derived human left ventricular modelling with fluid-structure interaction. Springer International Publishing

Aitken, E., Geddes, C., Thomson, P., Kasthuri, R., Chandramohan, M., Berry, C., Kingsmore, D. (2015) Immediate access arteriovenous grafts versus tunnelled central venous catheters: study protocol for a randomised controlled trial. Trials, 16, (doi: 10.1186/s13063-015-0556-x)

Dalzell, J. R., Cannon, J. A., Simpson, J., Gardner, R. S., Petrie, M. C. (2015) Improving outcomes in peripartum cardiomyopathy. Expert Review of Cardiovascular Therapy, 13, pp. 665-671. (doi: 10.1586/14779072.2015.1040767)

Mangion, K., Carrick, D., Payne, A., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K., Berry, C. (2015) Infarct burden following multivessel PCI vs. infarct-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O9)

Souteyrand, G., Amabile, N., Combaret, N., Hammas, S., Prati, F., Berry, C., Pereira, B., Lusson, J.-R., Caussin, C., Motreff, P. (2015) Invasive management without stents in selected acute coronary syndrome patients with a large thrombus burden: a prospective study of optical coherence tomography guided treatment decisions. EuroIntervention, 11, pp. 895-904. (doi: 10.4244/eijy14m07_18)

Hennigan, B., Robertson, K., Berry, C., Oldroyd, K. G. (2015) Is hyperaemia essential for accurate functional assessment of coronary stenosis severity? Interventional Cardiology Review, 10, pp. 72-78. (doi: 10.15420/icr.2015.10.2.72)

Mangion, K., Carrick, D., Payne, A. R., McClure, J., Mason, M., Petrie, M., McEntegart, M., Eteiba, H., Oldroyd, K. G., Berry, C. (2015) Left ventricular outcomes following multivessel PCI vs. infarct artery-only PCI in patients with acute STEMI: the Glasgow PRAMI CMR sub-study. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-P104)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Pathophysiology of myocardial remodeling in survivors of ST-elevation myocardial infarction revealed by native T1 mapping: inflammation, remote myocardium and prognostic significance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-Q52)

Robertson, K. E., Hennigan, B., Berry, C., Oldroyd, K. G. (2015) Physiological assessment of coronary lesion severity. Coronary Artery Disease, 26, pp. e8-e14. (doi: 10.1097/MCA.0000000000000212)

Carrick, D., Haig, C., Rauhalammi, S. M., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K. G., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by non-contrast T1 mapping cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O26)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of infarct core pathology in ST-elevation myocardial infarction survivors revealed by quantitative T2-weighted cardiac magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 17, (doi: 10.1186/1532-429X-17-S1-O54)

Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M., Eteiba, H., Hood, S., Watkins, S., Lindsay, M., Marous, A., Radjenovic, A., Ford, I., Tzemos, N., Oldroyd, K., Berry, C. (2015) Prognostic significance of quantitative measures of myocardial infarct pathology using native T1 mapping, in survivors of ST-elevation myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 17, pp. O53. (doi: 10.1186/1532-429X-17-S1-O53)

McGirr, A., Lipina, T. V., Mun, H.-S., Georgiou, J., Al-Amri, A. H., Ng, E., Zhai, D., Elliott, C., Cameron, R. T., Mullins, J. G., Liu, F., Baillie, G. S., Clapcote, S. J., Roder, J. C. (2015) Specific inhibition of phosphodiesterase-4B results in anxiolysis and facilitates memory acquisition. Neuropsychopharmacology, 41, pp. 1080-1092. (doi: 10.1038/npp.2015.240)

Kwok, C. S., Kontopantelis, E., Myint, P. K., Zaman, A., Berry, C., Keavney, B., Nolan, J., Ludman, P. F., de Belder, M. A., Buchan, I., Mamas, M. A. (2015) Stroke following percutaneous coronary intervention: type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007–12. European Heart Journal, 36, pp. 1618-1628. (doi: 10.1093/eurheartj/ehv113)

Byrne, A. M., Elliott, C., Hoffmann, R., Baillie, G. S. (2015) The activity of cAMP-Phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus. FEBS Letters, 589, pp. 750-755. (doi: 10.1016/j.febslet.2015.02.004)

Badar, A. A., Brunton, A. P.T., Mahmood, A. H., Dobbin, S., Pozzi, A., McMinn, J. F., Sinclair, A. J.E., Gardner, R. S., Petrie, M. C., Curry, P. A., Al-Attar, N. H.K., Pettit, S. J. (2015) The management of patients with aortic regurgitation and severe left ventricular dysfunction: a systematic review. Expert Review of Cardiovascular Therapy, 13, pp. 915-922. (doi: 10.1586/14779072.2015.1067139)

PGR Students

 

Rebecca Gilchrist

  • Postgraduate Research student
  • Research title: The role of population heterogeneity in electrophysiology in

Cardiac electrophysiology is highly regulated to maintain spatiotemporal homogeneity, which is fundamental to stable cardiac rhythm. Cardiac arrhythmias are complex and dynamic phenomena, often requiring interacting mechanisms to initiate and sustain them. Determining arrhythmia mechanisms requires not only an understanding of the ion channel behaviour which determines cardiomyocyte electrophysiology but also of tissue and organ-level factors which influence conduction and repolarization in the heart. Our research takes a multi-scale and multi-disciplinary approach, leveraging molecular, cellular and whole-heart studies to understand atrial and ventricular arrhythmia mechanisms.

Specific areas covered:

  • Regulation and post-translational modification of cardiac ion channels and signalling proteins
  • How pro-arrhythmic early afterdepolarisations (EADs) can be prevented in atrial myocytes
  • How remodelling after myocardial infarction and in heart failure promotes atrial and ventricular arrhythmia
  • Mechanisms of initiation of ventricular arrhythmias in the inherited long QT syndrome (LQTS)
  • Regenerative medicine approaches using iPSC-derived cardiomyocytes to address scar-related arrhythmia
  • Identification of new therapeutic targets to prevent ventricular arrhythmias
  • Development of novel therapeutic approaches to target ventricular arrhythmias

Wider impact of research

Our research is mechanistically focused, with the clear aim that we will discover new therapeutic targets for translation into clinical use through understanding mechanisms. The drivers for our research are two key problems faced by clinicians caring for patients with heart rhythm disorders:

Atrial fibrillation (AF) is the commonest cardiac arrhythmia, affecting ~1% of the general population. It substantially increases the risk of stroke, heart failure and death. Currently available anti-arrhythmic drugs are only modestly effective and frequently have adverse effects. At present, the most effective therapy is an invasive procedure called catheter ablation. Our work aims to understand these mechanisms at atrial cell and tissue level and so to identify new drug targets for the treatment and prevention of AF.

Ventricular arrhythmias are associated with a risk of sudden death and can be caused by various underlying conditions, from inherited conditions (including LQTS) to myocardial infarction (MI) and heart failure. The only fully effective protection against sudden death is to implant a defibrillator (ICD), an invasive procedure that is costly and carries long-term risks. Our work aims to understand who is at risk so that ICDs can be used only where really needed and to identify novel therapies to prevent the development of ventricular arrhythmias rather than simply using shocks to terminate them when they occur.