Dr Ninian Lang

  • Clinical Senior Lecturer (Institute of Cardiovascular & Medical Sciences)

Biography

Ninian Lang is a Clinical Senior Lecturer in Cardiology. He serves as an Honorary Consultant Cardiologist at the Queen Elizabeth University Hospital and the Beatson West of Scotland Cancer Centre. His clinical and academic work focuses on cardiovascular oncology and heart failure.

He runs the West of Scotland cardio-oncology service and integrates this clinical practice with an active research programme. His clinical trial and translational research in cardio-oncology relates to vascular and myocardial injury induced by established and novel chemotherapeutic agents. His heart failure research includes clinical trials and clinical mechanistic studies of vascular and cardiac pharmacology.

He is a graduate of the University of Edinburgh Medical School (BSc [Neuroscience], 1st class Hons, 1998; MBChB 2001, Annandale Gold Medal in Clinical Surgery). He undertook the majority of his clinical training in cardiology in Lothian. He was awarded the Bristol-Myers Squibb Cardiovascular Prize Fellowship to undertake his PhD research (University of Edinburgh; awarded 2009). He was subsequently appointed as Lecturer in Cardiology at the University of Edinburgh, followed by a fellowship in advanced heart failure and cardiac devices at the Scottish Advanced Heart Failure Service. He was appointed as a consultant cardiologist in 2014 before moving to a substantive position with the University of Glasgow.

Research interests

Cardiovascular Oncology

 -          Anthracycline-related cardiotoxicity

-          VEGF signalling pathway inhibitor-induced vascular and cardiac toxicity

-          Cisplatin-induced cardiovascular toxicity (acute and latent)

-          Epidemiology of cardiovascular disease in patients with previous cancer

 

Heart Failure

-          Translational studies of vascular function in vivo

-          Clinical trials

-          Nitroxyl (HNO) donors

  • UK Lead for STANDUP-AHF trial, local PI STANDUP-Imaging

-          Intravenous iron therapy

  • Local PI IRONMAN trial

 

 

 

Publications

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Jump to: 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2005 | 2004
Number of items: 50.

2020

Lang, N. N. , Dobbin, S. J.H. and Petrie, M. C. (2020) Vericiguat in worsening heart failure – agonising over, or celebrating, agonism. Cardiovascular Research, (Accepted for Publication)

Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, (doi: 10.1093/cvr/cvaa209) (PMID:32702087) (Accepted for Publication)

Cameron, A. C. et al. (2020) Comprehensive characterisation of the vascular effects of cisplatin-based chemotherapy in patients with testicular cancer. JACC: CardioOncology, (Accepted for Publication)

Dobbin, S. J.H. et al. (2020) Cardiotoxicity and myocardial hypoperfusion associated with anti-VEGF therapies: prospective cardiac magnetic resonance imaging in patients with cancer. European Journal of Heart Failure, (doi: 10.1002/ejhf.1847) (Early Online Publication)

Tzolos, E. et al. (2020) Dynamic changes in high-sensitivity cardiac troponin I in response to anthracycline-based chemotherapy. Clinical Oncology, (doi: 10.1016/j.clon.2019.11.008) (PMID:31813662) (In Press)

2019

Cameron, A. C. et al. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74(6), pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343) (PMID:31587571)

Cameron, A. C., Welsh, P. , Neves, K. B. , Newby, D., Touyz, R. M. and Lang, N. (2019) Acute vascular effects of vascular endothelial growth factor inhibition in the forearm arterial circulation. Journal of Hypertension, (doi: 10.1097/HJH.0000000000002230) (PMID:31449168) (Early Online Publication)

Ahmad, F. A., Petrie, M. C. , McMurray, J. J.V. and Lang, N. N. (2019) Personalized medicine and hospitalization for heart failure: if we understand it, we may be successful in treating it. European Journal of Heart Failure, 21(6), pp. 699-702. (doi: 10.1002/ejhf.1463) (PMID:30972879) (PMCID:PMC6618029)

Cameron, A. C., Rossitto, G., Lang, N. N. and Touyz, R. M. (2019) Antihypertensive drugs and vascular health. In: Zimlichman, R., Julius, S. and Mancia, G. (eds.) Prehypertension and Cardiometabolic Syndrome. Series: Updates in hypertension and cardiovascular protection. Springer, pp. 585-605. ISBN 9783319753096 (doi:10.1007/978-3-319-75310-2_37)

Cameron, A. C., Touyz, R. M. and Lang, N. N. (2019) Vascular biology of cancer chemotherapeutic drugs. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 259-268. ISBN 9783030164805 (doi:10.1007/978-3-030-16481-2_24)

2018

Dobbin, S. J.H. , Cameron, A. C., Petrie, M. C. , Jones, R. J. , Touyz, R. M. and Lang, N. N. (2018) Toxicity of cancer therapy: what the cardiologist needs to know about angiogenesis inhibitors. Heart, 104(24), pp. 1995-2002. (doi: 10.1136/heartjnl-2018-313726) (PMID:30228246) (PMCID:PMC6268130)

Lang, N. N. and Walker, N. L. (2018) Adult congenital heart disease and radiation exposure: the malignant price of cardiac care. Circulation, 137(13), pp. 1346-1348. (doi: 10.1161/CIRCULATIONAHA.117.032815) (PMID:29581364)

2017

Noh, R. M., Venkatasubramanian, S., Daga, S., Langrish, J., Mills, N. L., Lang, N. N. , Hoffmann, E., Waterhouse, B., Newby, D. E. and Frier, B. M. (2017) Cardiometabolic effects of a novel SIRT1 activator, SRT2104, in people with type 2 diabetes mellitus. Open Heart, 4(2), e000647. (doi: 10.1136/openhrt-2017-000647) (PMID:28912956) (PMCID:PMC5588958)

Touyz, R. M. , Lang, N. N. , Herrmann, J., van den Meiracker, A. H. and Danser, A.H. J. (2017) Recent advances in hypertension and cardiovascular toxicities with vascular endothelial growth factor inhibition. Hypertension, 70(2), pp. 220-226. (doi: 10.1161/HYPERTENSIONAHA.117.08856) (PMID:28630211)

Cameron, A. C., Lang, N. N. and Touyz, R. M. (2017) Cardiovascular complications from cancer therapy: hypertension-focus on vascular endothelial growth factor inhibitors. In: Herrmann, J. (ed.) Clinical Cardio-oncology. Elesvier: Amsterdam, pp. 185-211. ISBN 9780323442275 (doi:10.1016/B978-0-323-44227-5.00010-7)

2016

Cameron, A. C., Lang, N. N. and Touyz, R. M. (2016) Drug treatment of hypertension: focus on vascular health. Drugs, 76(16), pp. 1529-1550. (doi: 10.1007/s40265-016-0642-8) (PMID:27667708)

Stirrat, C. G., Venkatasubramanian, S., Pawade, T., Mitchell, A. J., Shah, A. S., Lang, N. N. and Newby, D. E. (2016) Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure. British Journal of Clinical Pharmacology, 82(4), pp. 974-982. (doi: 10.1111/bcp.13033) (PMID:27275843) (PMCID:PMC5104489)

Pedersen, C. M. et al. (2016) Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury. British Journal of Clinical Pharmacology, 81(6), pp. 1037-1045. (doi: 10.1111/bcp.12882) (PMID:26750458)

Venkatasubramanian, S. et al. (2016) Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus. Open Heart, 3(1), e000402. (doi: 10.1136/openhrt-2016-000402) (PMID:27239324) (PMCID:PMC4879341)

2015

Cameron, A. C., Touyz, R. M. and Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32(7), pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023) (PMID:26968393) (PMCID:PMC4989034)

2014

Lang, N. N. , Badar, A. A., Pettit, S. J., Templeton, S., Connelly, D. T. and Gardner, R. S. (2014) Interventricular lead separation is critical for NT-proBNP reduction after cardiac resynchronization therapy. Biomarkers in Medicine, 8(6), pp. 797-806. (doi: 10.2217/BMM.13.159) (PMID:25224936)

Dalzell, J. R., Cannon, J. A., Jackson, C. E., Lang, N. N. and Gardner, R. S. (2014) Emerging biomarkers for heart failure: an update. Biomarkers in Medicine, 8(6), pp. 833-840. (doi: 10.2217/bmm.14.51) (PMID:25224939)

Lang, N. N. , Wong, C. M., Dalzell, J. R., Jansz, S., Leslie, S. J. and Gardner, R. S. (2014) The ease of use and reproducibility of the Alere™ Heart Check System: a comparison of patient and healthcare professional measurement of BNP. Biomarkers in Medicine, 8(6), pp. 791-796. (doi: 10.2217/bmm.14.48) (PMID:25224935)

Liu, D., Fernandez, B. O., Hamilton, A., Lang, N. N. , Gallagher, J. M.C., Newby, D. E., Feelisch, M. and Weller, R. B. (2014) UVA irradiation of human skin vasodilates arterial vasculature and lowers blood pressure independently of nitric oxide synthase. Journal of Investigative Dermatology, 134(7), pp. 1839-1846. (doi: 10.1038/jid.2014.27) (PMID:24445737)

McMinn, J. F., Lang, N. N. , McPhadden, A., Payne, J. R., Petrie, M. C. and Gardner, R. S. (2014) Biomarkers of acute rejection following cardiac transplantation. Biomarkers in Medicine, 8(6), pp. 815-832. (doi: 10.2217/bmm.14.56) (PMID:25224938)

Payne, J. and Lang, N. (2014) Heart failure resistant to standard medical therapy. In: Smith, R., Higgins, M. and Macfie, A. (eds.) Cardiothoracic Critical Care. Series: Oxford specialist handbooks in critical care. Oxford University Press. ISBN 9780199692958 (doi:10.1093/med/9780199692958.003.0021)

2013

Tsang, H. et al. (2013) Role of asymmetric methylarginine and connexin 43 in the regulation of pulmonary endothelial function. Pulmonary Circulation, 3(3), pp. 675-691. (doi: 10.1086/674440) (PMID:24618552) (PMCID:PMC4070793)

Venkatasubramanian, S. et al. (2013) Cardiovascular effects of a novel SIRT1 activator, SRT2104, in otherwise healthy cigarette smokers. Journal of the American Heart Association, 2(3), e000042. (doi: 10.1161/JAHA.113.000042) (PMID:23770971) (PMCID:PMC3698759)

Japp, A. G. et al. (2013) Effect of PSI-697, a novel P-selectin inhibitor, on platelet-monocyte aggregate formation in humans. Journal of the American Heart Association, 2(1), e006007. (doi: 10.1161/JAHA.112.006007) (PMID:23525448) (PMCID:PMC3603266)

Venkatasubramanian, S., Griffiths, M. E., McLean, S. G., Miller, M. R., Luo, R., Lang, N. N. and Newby, D. E. (2013) Vascular effects of Urocortins 2 and 3 in healthy volunteers. Journal of the American Heart Association, 2(1), e004267. (PMID:23525432) (PMCID:PMC3603262)

Lang, N.N. (2013) Cardiology Symposium 2012 Report held on 15 November at the Royal College of Physicians of Edinburgh. Journal of the Royal College of Physicians of Edinburgh, 43(2), pp. 159-160. (doi: 10.4997/JRCPE.2013.214)

Lang, N.N. and Connelly, D.T. (2013) Novel oral anticoagulants for the prevention of thromboembolism in patients with atrial fibrillation. Journal of the Royal College of Physicians of Edinburgh, 43(2), pp. 151-158. (doi: 10.4997/JRCPE.2013.213)

2012

Alam, S. R. et al. (2012) Ultrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experience. Circulation: Cardiovascular Imaging, 5(5), pp. 559-565. (doi: 10.1161/CIRCIMAGING.112.974907) (PMID:22875883)

Lang, N.N. and Newby, D.E. (2012) Cardiac compression causing fatal acute ST-segment elevation myocardial infarction. QJM: An International Journal of Medicine, 105(9), pp. 883-885. (doi: 10.1093/qjmed/hcr131) (PMID:21804101)

Richards, J. M.J. et al. (2012) In vivo mononuclear cell tracking using superparamagnetic particles of iron oxide: feasibility and safety in humans. Circulation: Cardiovascular Imaging, 5(4), pp. 509-517. (doi: 10.1161/CIRCIMAGING.112.972596) (PMID:22787016)

Cruden, N. L.M., Lang, N. N. , MacGillivray, T. J., Uren, N. G., Fox, K. A.A. and Newby, D. E. (2012) Vasomotor and fibrinolytic responses to kinin receptor agonists in the atherosclerotic human lower limb. Heart and Vessels, 27(2), pp. 179-185. (doi: 10.1007/s00380-011-0124-6) (PMID:21394642)

2011

Lang, N. N. , Guðmundsdóttir, I. J. and Newby, D. E. (2011) Vascular PAR-1: activity and antagonism. Cardiovascular Therapeutics, 29(6), pp. 349-361. (doi: 10.1111/j.1755-5922.2010.00140.x) (PMID:20528879)

2010

Lang, N. and Fox, K. (2010) Current drug therapies used in the secondary prevention of MI. Prescriber, 21(19), pp. 22-45. (doi: 10.1002/psb.675)

Venkatasubramanian, S., Newby, D. E. and Lang, N. N. (2010) Urocortins in heart failure. Biochemical Pharmacology, 80(3), pp. 289-296. (doi: 10.1016/j.bcp.2010.03.032) (PMID:20363214)

2009

Mills, N.L., Tura, O., Padfield, G.J., Millar, C., Lang, N.N. , Stirling, D., Ludlam, C., Turner, M.L., Barclay, G.R. and Newby, D.E. (2009) Dissociation of phenotypic and functional endothelial progenitor cells in patients undergoing percutaneous coronary intervention. Heart, 95(24), pp. 2003-2008. (doi: 10.1136/hrt.2008.163162) (PMID:19482845)

2008

Lang, N. N. , Cruden, N. L., Tse, G. H., Bloomfield, P., Ludlam, C. A., Fox, K. A. and Newby, D. E. (2008) Vascular B1 kinin receptors in patients with congestive heart failure. Journal of Cardiovascular Pharmacology, 52(5), pp. 438-444. (doi: 10.1097/FJC.0b013e31818c66cb) (PMID:19033823)

Lang, N. N. , Guðmundsdóttir, I. J., Boon, N. N., Ludlam, C. A., Fox, K. A. and Newby, D. E. (2008) Marked impairment of protease-activated receptor type 1-mediated vasodilation and fibrinolysis in cigarette smokers. Journal of the American College of Cardiology, 52(1), pp. 33-39. (doi: 10.1016/j.jacc.2008.04.003) (PMID:18582632)

Guðmundsdóttir, I. J., Lang, N. N. , Boon, N. A., Ludlam, C. A., Webb, D. J., Fox, K. A. and Newby, D. E. (2008) Role of the endothelium in the vascular effects of the thrombin receptor (protease-activated receptor type 1) in humans. Journal of the American College of Cardiology, 51(18), pp. 1749-1756. (doi: 10.1016/j.jacc.2007.12.047) (PMID:18452780)

Lang, N. and Fox, K. (2008) Current drug therapies for the secondary prevention of MI. Prescriber, 19(1), pp. 14-25. (doi: 10.1002/psb.173)

Lang, N.N. , Myles, R.C., Burton, F.L., Hall, D.P., Chin, Y.Z., Boon, N.A. and Newby, D.E. (2008) The vascular effects of rotigaptide in vivo in man. Biochemical Pharmacology, 76(10), pp. 1194-1200. (doi: 10.1016/j.bcp.2008.08.022)

Lang, N. N. and Newby, D. E. (2008) Investigation of patients with suspected chronic heart failure. In: Kearney, M. (ed.) Chronic Heart Failure. Series: Oxford cardiology library. Oxford University Press: Oxford, pp. 23-34. ISBN 9780199542338 (doi:10.1093/med/9780199542338.003.0003)

2007

Lang, N. N. , Luksha, L., Newby, D. E. and Kublickiene, K. (2007) Connexin 43 mediates endothelium-derived hyperpolarizing factor-induced vasodilatation in subcutaneous resistance arteries from healthy pregnant women. American Journal of Physiology: Heart and Circulatory Physiology, 292(2), H1026-H1032. (doi: 10.1152/ajpheart.00797.2006) (PMID:17085540)

Lang, N. N. and Newby, D. E. (2007) Emerging thrombotic effects of drug eluting stents. Arteriosclerosis, Thrombosis, and Vascular Biology, 27(2), pp. 261-262. (doi: 10.1161/01.ATV.0000255308.41576.ae) (PMID:17229968)

2005

Lang, N. and Fox, K. (2005) Current drug therapies for the secondary prevention of MI. Prescriber, 16(12), pp. 33-44.

2004

Lang, N. , Davie, R., Whitworth, C., Winney, R. and Hughes, J. (2004) Fatal calcific uraemic arteriolopathy (CUA): a case report and review of the literature. Scottish Medical Journal, 49(3), pp. 108-111. (doi: 10.1177/003693300404900313) (PMID:15462229)

This list was generated on Fri Aug 14 23:31:58 2020 BST.
Number of items: 50.

Articles

Lang, N. N. , Dobbin, S. J.H. and Petrie, M. C. (2020) Vericiguat in worsening heart failure – agonising over, or celebrating, agonism. Cardiovascular Research, (Accepted for Publication)

Mangion, K. et al. (2020) The Chief Scientist Office cardiovascular and pulmonary imaging in SARS Coronavirus disease-19 (CISCO-19) study. Cardiovascular Research, (doi: 10.1093/cvr/cvaa209) (PMID:32702087) (Accepted for Publication)

Cameron, A. C. et al. (2020) Comprehensive characterisation of the vascular effects of cisplatin-based chemotherapy in patients with testicular cancer. JACC: CardioOncology, (Accepted for Publication)

Dobbin, S. J.H. et al. (2020) Cardiotoxicity and myocardial hypoperfusion associated with anti-VEGF therapies: prospective cardiac magnetic resonance imaging in patients with cancer. European Journal of Heart Failure, (doi: 10.1002/ejhf.1847) (Early Online Publication)

Tzolos, E. et al. (2020) Dynamic changes in high-sensitivity cardiac troponin I in response to anthracycline-based chemotherapy. Clinical Oncology, (doi: 10.1016/j.clon.2019.11.008) (PMID:31813662) (In Press)

Cameron, A. C. et al. (2019) Progressive hypertension and severe left ventricular outflow tract obstruction. Hypertension, 74(6), pp. 1216-1225. (doi: 10.1161/hypertensionaha.119.13343) (PMID:31587571)

Cameron, A. C., Welsh, P. , Neves, K. B. , Newby, D., Touyz, R. M. and Lang, N. (2019) Acute vascular effects of vascular endothelial growth factor inhibition in the forearm arterial circulation. Journal of Hypertension, (doi: 10.1097/HJH.0000000000002230) (PMID:31449168) (Early Online Publication)

Ahmad, F. A., Petrie, M. C. , McMurray, J. J.V. and Lang, N. N. (2019) Personalized medicine and hospitalization for heart failure: if we understand it, we may be successful in treating it. European Journal of Heart Failure, 21(6), pp. 699-702. (doi: 10.1002/ejhf.1463) (PMID:30972879) (PMCID:PMC6618029)

Dobbin, S. J.H. , Cameron, A. C., Petrie, M. C. , Jones, R. J. , Touyz, R. M. and Lang, N. N. (2018) Toxicity of cancer therapy: what the cardiologist needs to know about angiogenesis inhibitors. Heart, 104(24), pp. 1995-2002. (doi: 10.1136/heartjnl-2018-313726) (PMID:30228246) (PMCID:PMC6268130)

Lang, N. N. and Walker, N. L. (2018) Adult congenital heart disease and radiation exposure: the malignant price of cardiac care. Circulation, 137(13), pp. 1346-1348. (doi: 10.1161/CIRCULATIONAHA.117.032815) (PMID:29581364)

Noh, R. M., Venkatasubramanian, S., Daga, S., Langrish, J., Mills, N. L., Lang, N. N. , Hoffmann, E., Waterhouse, B., Newby, D. E. and Frier, B. M. (2017) Cardiometabolic effects of a novel SIRT1 activator, SRT2104, in people with type 2 diabetes mellitus. Open Heart, 4(2), e000647. (doi: 10.1136/openhrt-2017-000647) (PMID:28912956) (PMCID:PMC5588958)

Touyz, R. M. , Lang, N. N. , Herrmann, J., van den Meiracker, A. H. and Danser, A.H. J. (2017) Recent advances in hypertension and cardiovascular toxicities with vascular endothelial growth factor inhibition. Hypertension, 70(2), pp. 220-226. (doi: 10.1161/HYPERTENSIONAHA.117.08856) (PMID:28630211)

Cameron, A. C., Lang, N. N. and Touyz, R. M. (2016) Drug treatment of hypertension: focus on vascular health. Drugs, 76(16), pp. 1529-1550. (doi: 10.1007/s40265-016-0642-8) (PMID:27667708)

Stirrat, C. G., Venkatasubramanian, S., Pawade, T., Mitchell, A. J., Shah, A. S., Lang, N. N. and Newby, D. E. (2016) Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure. British Journal of Clinical Pharmacology, 82(4), pp. 974-982. (doi: 10.1111/bcp.13033) (PMID:27275843) (PMCID:PMC5104489)

Pedersen, C. M. et al. (2016) Rotigaptide protects the myocardium and arterial vasculature from ischaemia reperfusion injury. British Journal of Clinical Pharmacology, 81(6), pp. 1037-1045. (doi: 10.1111/bcp.12882) (PMID:26750458)

Venkatasubramanian, S. et al. (2016) Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus. Open Heart, 3(1), e000402. (doi: 10.1136/openhrt-2016-000402) (PMID:27239324) (PMCID:PMC4879341)

Cameron, A. C., Touyz, R. M. and Lang, N. N. (2015) Vascular complications of cancer chemotherapy. Canadian Journal of Cardiology, 32(7), pp. 852-862. (doi: 10.1016/j.cjca.2015.12.023) (PMID:26968393) (PMCID:PMC4989034)

Lang, N. N. , Badar, A. A., Pettit, S. J., Templeton, S., Connelly, D. T. and Gardner, R. S. (2014) Interventricular lead separation is critical for NT-proBNP reduction after cardiac resynchronization therapy. Biomarkers in Medicine, 8(6), pp. 797-806. (doi: 10.2217/BMM.13.159) (PMID:25224936)

Dalzell, J. R., Cannon, J. A., Jackson, C. E., Lang, N. N. and Gardner, R. S. (2014) Emerging biomarkers for heart failure: an update. Biomarkers in Medicine, 8(6), pp. 833-840. (doi: 10.2217/bmm.14.51) (PMID:25224939)

Lang, N. N. , Wong, C. M., Dalzell, J. R., Jansz, S., Leslie, S. J. and Gardner, R. S. (2014) The ease of use and reproducibility of the Alere™ Heart Check System: a comparison of patient and healthcare professional measurement of BNP. Biomarkers in Medicine, 8(6), pp. 791-796. (doi: 10.2217/bmm.14.48) (PMID:25224935)

Liu, D., Fernandez, B. O., Hamilton, A., Lang, N. N. , Gallagher, J. M.C., Newby, D. E., Feelisch, M. and Weller, R. B. (2014) UVA irradiation of human skin vasodilates arterial vasculature and lowers blood pressure independently of nitric oxide synthase. Journal of Investigative Dermatology, 134(7), pp. 1839-1846. (doi: 10.1038/jid.2014.27) (PMID:24445737)

McMinn, J. F., Lang, N. N. , McPhadden, A., Payne, J. R., Petrie, M. C. and Gardner, R. S. (2014) Biomarkers of acute rejection following cardiac transplantation. Biomarkers in Medicine, 8(6), pp. 815-832. (doi: 10.2217/bmm.14.56) (PMID:25224938)

Tsang, H. et al. (2013) Role of asymmetric methylarginine and connexin 43 in the regulation of pulmonary endothelial function. Pulmonary Circulation, 3(3), pp. 675-691. (doi: 10.1086/674440) (PMID:24618552) (PMCID:PMC4070793)

Venkatasubramanian, S. et al. (2013) Cardiovascular effects of a novel SIRT1 activator, SRT2104, in otherwise healthy cigarette smokers. Journal of the American Heart Association, 2(3), e000042. (doi: 10.1161/JAHA.113.000042) (PMID:23770971) (PMCID:PMC3698759)

Japp, A. G. et al. (2013) Effect of PSI-697, a novel P-selectin inhibitor, on platelet-monocyte aggregate formation in humans. Journal of the American Heart Association, 2(1), e006007. (doi: 10.1161/JAHA.112.006007) (PMID:23525448) (PMCID:PMC3603266)

Venkatasubramanian, S., Griffiths, M. E., McLean, S. G., Miller, M. R., Luo, R., Lang, N. N. and Newby, D. E. (2013) Vascular effects of Urocortins 2 and 3 in healthy volunteers. Journal of the American Heart Association, 2(1), e004267. (PMID:23525432) (PMCID:PMC3603262)

Lang, N.N. (2013) Cardiology Symposium 2012 Report held on 15 November at the Royal College of Physicians of Edinburgh. Journal of the Royal College of Physicians of Edinburgh, 43(2), pp. 159-160. (doi: 10.4997/JRCPE.2013.214)

Lang, N.N. and Connelly, D.T. (2013) Novel oral anticoagulants for the prevention of thromboembolism in patients with atrial fibrillation. Journal of the Royal College of Physicians of Edinburgh, 43(2), pp. 151-158. (doi: 10.4997/JRCPE.2013.213)

Alam, S. R. et al. (2012) Ultrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experience. Circulation: Cardiovascular Imaging, 5(5), pp. 559-565. (doi: 10.1161/CIRCIMAGING.112.974907) (PMID:22875883)

Lang, N.N. and Newby, D.E. (2012) Cardiac compression causing fatal acute ST-segment elevation myocardial infarction. QJM: An International Journal of Medicine, 105(9), pp. 883-885. (doi: 10.1093/qjmed/hcr131) (PMID:21804101)

Richards, J. M.J. et al. (2012) In vivo mononuclear cell tracking using superparamagnetic particles of iron oxide: feasibility and safety in humans. Circulation: Cardiovascular Imaging, 5(4), pp. 509-517. (doi: 10.1161/CIRCIMAGING.112.972596) (PMID:22787016)

Cruden, N. L.M., Lang, N. N. , MacGillivray, T. J., Uren, N. G., Fox, K. A.A. and Newby, D. E. (2012) Vasomotor and fibrinolytic responses to kinin receptor agonists in the atherosclerotic human lower limb. Heart and Vessels, 27(2), pp. 179-185. (doi: 10.1007/s00380-011-0124-6) (PMID:21394642)

Lang, N. N. , Guðmundsdóttir, I. J. and Newby, D. E. (2011) Vascular PAR-1: activity and antagonism. Cardiovascular Therapeutics, 29(6), pp. 349-361. (doi: 10.1111/j.1755-5922.2010.00140.x) (PMID:20528879)

Lang, N. and Fox, K. (2010) Current drug therapies used in the secondary prevention of MI. Prescriber, 21(19), pp. 22-45. (doi: 10.1002/psb.675)

Venkatasubramanian, S., Newby, D. E. and Lang, N. N. (2010) Urocortins in heart failure. Biochemical Pharmacology, 80(3), pp. 289-296. (doi: 10.1016/j.bcp.2010.03.032) (PMID:20363214)

Mills, N.L., Tura, O., Padfield, G.J., Millar, C., Lang, N.N. , Stirling, D., Ludlam, C., Turner, M.L., Barclay, G.R. and Newby, D.E. (2009) Dissociation of phenotypic and functional endothelial progenitor cells in patients undergoing percutaneous coronary intervention. Heart, 95(24), pp. 2003-2008. (doi: 10.1136/hrt.2008.163162) (PMID:19482845)

Lang, N. N. , Cruden, N. L., Tse, G. H., Bloomfield, P., Ludlam, C. A., Fox, K. A. and Newby, D. E. (2008) Vascular B1 kinin receptors in patients with congestive heart failure. Journal of Cardiovascular Pharmacology, 52(5), pp. 438-444. (doi: 10.1097/FJC.0b013e31818c66cb) (PMID:19033823)

Lang, N. N. , Guðmundsdóttir, I. J., Boon, N. N., Ludlam, C. A., Fox, K. A. and Newby, D. E. (2008) Marked impairment of protease-activated receptor type 1-mediated vasodilation and fibrinolysis in cigarette smokers. Journal of the American College of Cardiology, 52(1), pp. 33-39. (doi: 10.1016/j.jacc.2008.04.003) (PMID:18582632)

Guðmundsdóttir, I. J., Lang, N. N. , Boon, N. A., Ludlam, C. A., Webb, D. J., Fox, K. A. and Newby, D. E. (2008) Role of the endothelium in the vascular effects of the thrombin receptor (protease-activated receptor type 1) in humans. Journal of the American College of Cardiology, 51(18), pp. 1749-1756. (doi: 10.1016/j.jacc.2007.12.047) (PMID:18452780)

Lang, N. and Fox, K. (2008) Current drug therapies for the secondary prevention of MI. Prescriber, 19(1), pp. 14-25. (doi: 10.1002/psb.173)

Lang, N.N. , Myles, R.C., Burton, F.L., Hall, D.P., Chin, Y.Z., Boon, N.A. and Newby, D.E. (2008) The vascular effects of rotigaptide in vivo in man. Biochemical Pharmacology, 76(10), pp. 1194-1200. (doi: 10.1016/j.bcp.2008.08.022)

Lang, N. N. , Luksha, L., Newby, D. E. and Kublickiene, K. (2007) Connexin 43 mediates endothelium-derived hyperpolarizing factor-induced vasodilatation in subcutaneous resistance arteries from healthy pregnant women. American Journal of Physiology: Heart and Circulatory Physiology, 292(2), H1026-H1032. (doi: 10.1152/ajpheart.00797.2006) (PMID:17085540)

Lang, N. N. and Newby, D. E. (2007) Emerging thrombotic effects of drug eluting stents. Arteriosclerosis, Thrombosis, and Vascular Biology, 27(2), pp. 261-262. (doi: 10.1161/01.ATV.0000255308.41576.ae) (PMID:17229968)

Lang, N. and Fox, K. (2005) Current drug therapies for the secondary prevention of MI. Prescriber, 16(12), pp. 33-44.

Lang, N. , Davie, R., Whitworth, C., Winney, R. and Hughes, J. (2004) Fatal calcific uraemic arteriolopathy (CUA): a case report and review of the literature. Scottish Medical Journal, 49(3), pp. 108-111. (doi: 10.1177/003693300404900313) (PMID:15462229)

Book Sections

Cameron, A. C., Rossitto, G., Lang, N. N. and Touyz, R. M. (2019) Antihypertensive drugs and vascular health. In: Zimlichman, R., Julius, S. and Mancia, G. (eds.) Prehypertension and Cardiometabolic Syndrome. Series: Updates in hypertension and cardiovascular protection. Springer, pp. 585-605. ISBN 9783319753096 (doi:10.1007/978-3-319-75310-2_37)

Cameron, A. C., Touyz, R. M. and Lang, N. N. (2019) Vascular biology of cancer chemotherapeutic drugs. In: Touyz, R. M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer: Cham, pp. 259-268. ISBN 9783030164805 (doi:10.1007/978-3-030-16481-2_24)

Cameron, A. C., Lang, N. N. and Touyz, R. M. (2017) Cardiovascular complications from cancer therapy: hypertension-focus on vascular endothelial growth factor inhibitors. In: Herrmann, J. (ed.) Clinical Cardio-oncology. Elesvier: Amsterdam, pp. 185-211. ISBN 9780323442275 (doi:10.1016/B978-0-323-44227-5.00010-7)

Payne, J. and Lang, N. (2014) Heart failure resistant to standard medical therapy. In: Smith, R., Higgins, M. and Macfie, A. (eds.) Cardiothoracic Critical Care. Series: Oxford specialist handbooks in critical care. Oxford University Press. ISBN 9780199692958 (doi:10.1093/med/9780199692958.003.0021)

Lang, N. N. and Newby, D. E. (2008) Investigation of patients with suspected chronic heart failure. In: Kearney, M. (ed.) Chronic Heart Failure. Series: Oxford cardiology library. Oxford University Press: Oxford, pp. 23-34. ISBN 9780199542338 (doi:10.1093/med/9780199542338.003.0003)

This list was generated on Fri Aug 14 23:31:58 2020 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • MARKERS AND MEDIATORS OF ANGIOGENESIS INHIBITOR-INDUCED VASCULAR AND MYOCARDIAL TOXICITY: A Prospective Study in Patients with Cancer
    British Heart Foundation
    2019 - 2021
     
  • How do arrhythmias and conduction disturbances contribute to death or rehospitalisation in patients discharged following an admission with acute heart failure? A prospective, observational, multi-centre cohort-study
    British Heart Foundation
    2017 - 2022
     
  • Cancer Chemotherapeutics and the Vasculature - Endothelial Effects of VEGF Inhibitorsion In Vivo in Man
    Chief Scientist Office
    2016 - 2018
     
  • Intermediate and Long Term Vascular Effects of Cisplatin in Patients with Testicular Cancer (INTELLECT)
    Mason Medical Research Foundation
    2016 - 2018