This course will cover biophysical techniques used in conjunction with chemical tools that allow distances to be measured within and between biological molecules.

This course consists of lectures, tutorials, laboratories and computer labs.

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A scientific report based on the laboratory practical (100%)

This course aims to:

■ Develop and enhance student understanding of biophysical techniques used to determine distances within and between molecules

■ Provide students with the opportunity to experience working with these techniques

By the end of this course students should be able to:

■ Critically discuss how intra- and inter- molecular distances can be measured using FRET, pulsed EPR, and NMR.

■ Evaluate and justify a choice of chemical tool to use in FRET, pulsed EPR, and NMR.

■ Collect, analyse, and critically interpret their own data acquired using one or more of these techniques.

■ Communicate effectively their own data in a suitable scientific format.

Students must submit at least 75% by weight of the components (including examinations) of the course's summative assessment.