Underpinning Bioscience Discovery
Prior infection enhances immune-epithelial cell interactions to control respiratory infections
The role of spatial and temporal mRNA expression in regulating astrocyte reactivity in health and disease.
How Does Mitochondrial Complex IV Regulate the Rate of Ageing?
Neurophysiological correlates of sleep-dependent memory consolidation in healthy ageing
Unravelling the structural and functional role of Base-J in kinetoplastids: an integrated chemical biological approach
Resilience and metabolic adaptation in extremophilic archaea: insights into microbial function under abiotic stress relevant to environmental health and agricultural sustainability
How does the iron-mitochondria crosstalk influence the NRF2-cellular homeostatic mechanism in the human immune- and inflammatory response?
Mapping the spatial distribution of ADGRL3 in dopamine-related circuits and associated alterations following region-specific knockout
Harnessing the increased complexity of Asgard Archaeal Proteasomes to Bioengineer plants with increased resilience to environmental stress
How glial cells safeguard brain energetics, cognition, and resilience to inflammation in health and ageing?
Moonlighting mitochondria: understanding why mitochondria import and metabolise methylated amino acids
Effect of potentially toxic elements on the health and wellbeing of African lions
Dynamic Multiomic Profiling of Single Sensory Neurons to Uncover Mechanisms of Plasticity
Exploring mitochondrial enzymes as target for anti Toxoplasmosis and anti malaria drugs
Allosterism and ligand-bias at the immunometabolic receptor GPR84
Multiplexed AMR biosensor using antifouling nanostructured materials based on colloidal quantum dots and SERS
Identification and characterisation of the ubiquitin ligases that regulate CIZ1 proteostasis and evaluation of their role in cell cycle regulation.
Unraveling the cellular and molecular mechanisms of postembryonic intestine remodeling.
Control of Intestinal Inflammation via Non-ionic Surfactant
Innovative Strategies to Treat Bovine Mastitis: Design and Mode of Action Investigation of Strathclyde-Minor Groove Binders
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The ‘black box’ of the trypanosome mitochondria: how does the mitochondrial intermembrane space of this parasite operate?
Metabolite GPCR Control of Insulin Signalling in 3D Cultured Adipocytes
Miniature transcription factors for the decoding of molecular basis for specific methylated DNA biorecognition
How Human Cells Edit Their RNA to Stay Healthy”
Investigating Genomic and Developmental Effects of Sex Chromosome Incompatibilities on Reproduction
Origins of a tangled bank: Adaptation and evolution in antibiotic-producing Streptomyces
Regulating nitrogen sense and sensibility: de novo non-coding RNAs in bacterial nitrogen metabolism and stress adaptation
CASE Projects
Finding the balance: Does methane mitigation come at a cost to cow welfare?
A multi-scale multi-modal analysis of Stau1 protein in stress granule formation and disassembly
