Dr Cicely Macnamara

  • Rankin-Sneddon Research Fellowship (Mathematics)

Biography

Career history

  • Rankin-Sneddon Fellow - University of Glasgow, since 2021
  • PDRA - University of St Andrews, 2015-2021

 

Qualifications

MSc Mathematical Biology (distinction) University of Dundee, 2014
PhD (Carnegie Scholarship), University of St Andrews, 2011
MMath Mathematics (First Class), University of St Andrews, 2007

 

 

 

Research interests

My broad interests in mathematical biology can be grouped primarily on the theme of cancer modelling. Specific interests include agent-based, force-based modelling of tumour growth and development with specific interest in the interplay between cancer cells and the tumour microenvironment; cancer-immune dynamics specifically models of oncolytic virotherpay; and  intracellular dynamics including models of gene regulatory networks. I use a wide range of modelling techniques both analytic and numerical to solve both deterministic and stochastic systems. In my current role I am developing a mathematical and computational framework for solid tumour growth using individual-based, force-based modelling techniques. In parallel I am working on a cross-institutional project developing an add-on tool for PhysiCell to enable simulation of more realistic cellular microenvironments.

Research units

Publications

List by: Type | Date

Jump to: 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2011 | 2010
Number of items: 11.

2021

Eliaš, J. and Macnamara, C. K. (2021) Mathematical modelling of p53 signalling during DNA damage response: a survey. International Journal of Molecular Sciences, 22(19), 10590. (doi: 10.3390/ijms221910590)

Macnamara, C. (2021) Biomechanical modelling of cancer: Agent‐based force‐based models of solid tumours within the context of the tumour microenvironment. Computational and Systems Oncology, 1(2), e1018. (doi: 10.1002/cso2.1018)

2020

Macnamara, C. K. , Caiazzo, A., Ramis-Conde, I. and Chaplain, M. A.J. (2020) Computational modelling and simulation of cancer growth and migration within a 3D heterogeneous tissue. Journal of Computational Science, 40, 101067. (doi: 10.1016/j.jocs.2019.101067)

2019

Macnamara, C. K. , Mitchell, E. I. and Chaplain, M. A.J. (2019) Spatial-stochastic modelling of synthetic gene regulatory networks. Journal of Theoretical Biology, 468, pp. 27-44. (doi: 10.1016/j.jtbi.2019.02.003) (PMID:30753839)

2018

Szymańska, Z., Cytowski, M., Mitchell, E., Macnamara, C. K. and Chaplain, M. A.J. (2018) Computational modelling of cancer development and growth: Modelling at multiple scales and multiscale modelling. Bulletin of Mathematical Biology, 80, pp. 1366-1403. (doi: 10.1007/s11538-017-0292-3)

2017

Macnamara, C. K. and Chaplain, M. A.J. (2017) Spatio-temporal models of synthetic genetic oscillators. Mathematical Biosciences and Engineering, 14(1), pp. 249-262. (doi: 10.3934/mbe.2017016)

2016

Macnamara, C. K. and Chaplain, M. A.J. (2016) Diffusion driven oscillations in gene regulatory networks. Journal of Theoretical Biology, 407, pp. 51-70. (doi: 10.1016/j.jtbi.2016.07.021) (PMID:27449790)

Eftimie, R., Macnamara, C.K. , Dushoff, J., Bramson, J.L. and Earn, D.J.D. (2016) Bifurcations and chaotic dynamics in a tumour-immune-virus system. Mathematical Modelling of Natural Phenomena, 11(5), pp. 65-85. (doi: 10.1051/mmnp/201611505)

2015

Macnamara, C. and Eftimie, R. (2015) Memory versus effector immune responses in oncolytic virotherapies. Journal of Theoretical Biology, 377, pp. 1-9. (doi: 10.1016/j.jtbi.2015.04.004) (PMID:25882747)

2011

Macnamara, C. K. and Roberts, B. (2011) The period ratio for kink and sausage modes in a magnetic slab. Astronomy and Astrophysics, 526, A75. (doi: 10.1051/0004-6361/201015460)

2010

Macnamara, C.K. and Roberts, B. (2010) Effects of thermal conduction and compressive viscosity on the period ratio of the slow mode. Astronomy and Astrophysics, 515, A41. (doi: 10.1051/0004-6361/200913409)

This list was generated on Mon Jan 17 11:04:31 2022 GMT.
Jump to: Articles
Number of items: 11.

Articles

Eliaš, J. and Macnamara, C. K. (2021) Mathematical modelling of p53 signalling during DNA damage response: a survey. International Journal of Molecular Sciences, 22(19), 10590. (doi: 10.3390/ijms221910590)

Macnamara, C. (2021) Biomechanical modelling of cancer: Agent‐based force‐based models of solid tumours within the context of the tumour microenvironment. Computational and Systems Oncology, 1(2), e1018. (doi: 10.1002/cso2.1018)

Macnamara, C. K. , Caiazzo, A., Ramis-Conde, I. and Chaplain, M. A.J. (2020) Computational modelling and simulation of cancer growth and migration within a 3D heterogeneous tissue. Journal of Computational Science, 40, 101067. (doi: 10.1016/j.jocs.2019.101067)

Macnamara, C. K. , Mitchell, E. I. and Chaplain, M. A.J. (2019) Spatial-stochastic modelling of synthetic gene regulatory networks. Journal of Theoretical Biology, 468, pp. 27-44. (doi: 10.1016/j.jtbi.2019.02.003) (PMID:30753839)

Szymańska, Z., Cytowski, M., Mitchell, E., Macnamara, C. K. and Chaplain, M. A.J. (2018) Computational modelling of cancer development and growth: Modelling at multiple scales and multiscale modelling. Bulletin of Mathematical Biology, 80, pp. 1366-1403. (doi: 10.1007/s11538-017-0292-3)

Macnamara, C. K. and Chaplain, M. A.J. (2017) Spatio-temporal models of synthetic genetic oscillators. Mathematical Biosciences and Engineering, 14(1), pp. 249-262. (doi: 10.3934/mbe.2017016)

Macnamara, C. K. and Chaplain, M. A.J. (2016) Diffusion driven oscillations in gene regulatory networks. Journal of Theoretical Biology, 407, pp. 51-70. (doi: 10.1016/j.jtbi.2016.07.021) (PMID:27449790)

Eftimie, R., Macnamara, C.K. , Dushoff, J., Bramson, J.L. and Earn, D.J.D. (2016) Bifurcations and chaotic dynamics in a tumour-immune-virus system. Mathematical Modelling of Natural Phenomena, 11(5), pp. 65-85. (doi: 10.1051/mmnp/201611505)

Macnamara, C. and Eftimie, R. (2015) Memory versus effector immune responses in oncolytic virotherapies. Journal of Theoretical Biology, 377, pp. 1-9. (doi: 10.1016/j.jtbi.2015.04.004) (PMID:25882747)

Macnamara, C. K. and Roberts, B. (2011) The period ratio for kink and sausage modes in a magnetic slab. Astronomy and Astrophysics, 526, A75. (doi: 10.1051/0004-6361/201015460)

Macnamara, C.K. and Roberts, B. (2010) Effects of thermal conduction and compressive viscosity on the period ratio of the slow mode. Astronomy and Astrophysics, 515, A41. (doi: 10.1051/0004-6361/200913409)

This list was generated on Mon Jan 17 11:04:31 2022 GMT.

Teaching

2021/22

  • Maths 2A: Multivariate Calculus