Professor Carl Goodyear

  • Professor of Translational Immunology, Director of Innovation, Engagement and Enterprise (Immunology & Infection)
  • Assistant Vice-Principal (Strategy & Resources) (Office of the Vice Principals)

telephone: 01413303865
email: Carl.Goodyear@glasgow.ac.uk

Sir Graeme Davies Building, Level 4, B421, University Place, Glasgow G12 8TA, G12 8TA

Import to contacts

ORCID iDhttps://orcid.org/0000-0001-5926-5941

Personal assistant: Mrs Joanne Shearer
telephone: 01413308496
email: Joanne.Shearer@glasgow.ac.uk

Research interests

Dr Goodyear’s research group is focused on understanding immunopathogenesis of disease (i.e., Rheumatoid Arthritis, Osteoarthritis, Multiple Myeloma & Guillian-Barre Syndrome) and translating this knowledge into viable therapeutic agents for patients. In parallel, Dr. Goodyear also leads a Translational Immunology programme, which provides the critical interface between clinical and basic science.

Dr Goodyear and his laboratory are funded by Arthritis Research UK, Association for International Cancer Research, Medical Research Scotland, European Commission, Chief Scientist Office, Medical Research Council, Nuffield Foundation, Glasgow Orthopaedic Research Charitable Trust,  Pfizer, and MedImmune.

Local collaborators include: Professors Cavanagh, Barrett, Ferrell, Gadegaard, Lockhart, McInnesNibbsWillison and Drs. Carmody, Crilly, Litherland, Milling, Porter, Siebert, Soutar. National & international collaborators include: Professors Isaacs (Newcastle, UK), Silverman (New York, USA), Van ’T Hof (Liverpool, UK) and Drs Chiaramonte (Milano, Italy), Hollan (Lillehammer, Norway), Pratt (Newcastle, UK).

 

 

Publications

List by: Type | Date

Jump to: 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999
Number of items: 109.

2024

Colton, H. et al. (2024) Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients. British Journal of Haematology, (doi: 10.1111/bjh.19874) (PMID:39551718) (Early Online Publication)

Asghar, S., Litherland, G. J., Cole, J. J., McInnes, I. B. , Meek, R.M.D., Lockhart, J. C., Goodyear, C. S. and Crilly, A. (2024) Small extracellular vesicles derived from synovial fibroblasts contain distinct miRNA profiles and contribute to chondrocyte damage in osteoarthritis. Arthritis Research and Therapy, 26(1), 167. (doi: 10.1186/s13075-024-03398-3) (PMID:39342381)

Goodyear, C. S. et al. (2024) Immunogenicity of third dose COVID-19 vaccine strategies in patients who are immunocompromised with suboptimal immunity following two doses (OCTAVE-DUO): an open-label, multicentre, randomised, controlled, phase 3 trial. Lancet Rheumatology, 6(6), e339-e351. (doi: 10.1016/S2665-9913(24)00065-1) (PMID:38734019)

2023

Jaffery, H. et al. (2023) IĸB Protein BCL3 as a controller of osteogenesis and bone health. Arthritis and Rheumatology, 75(12), 2148-2160-2148-2160. (doi: 10.1002/art.42639) (PMID:37410754)

FitzGerald, O. et al. (2023) Application of clinical and molecular profiling data to improve patient outcomes in psoriatic arthritis. Therapeutic Advances in Musculoskeletal Disease, 15, pp. 1-14. (doi: 10.1177/1759720x231192315) (PMID:37694182) (PMCID:PMC10492462)

Cole, S. et al. (2023) Differential regulation of IL-17A and IL-17F via STAT5 contributes to psoriatic disease. Journal of Allergy and Clinical Immunology, 152(3), pp. 783-798. (doi: 10.1016/j.jaci.2023.03.035) (PMID:37244461)

Ooms, A. et al. (2023) Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis. BMJ Open, 13(9), e078539. (doi: 10.1136/bmjopen-2023-078539) (PMID:37770264) (PMCID:PMC10546161)

Wing, E., Sutherland, C., Miles, K., Gray, D., Goodyear, C. S. , Otto, T. D. , Breusch, S., Cowan, G. and Gray, M. (2023) Double-negative-2 B cells are the major synovial plasma cell precursor in rheumatoid arthritis. Frontiers in Immunology, 14, 1241474. (doi: 10.3389/fimmu.2023.1241474) (PMID:37638026) (PMCID:PMC10450142)

Barnes, E. et al. (2023) SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease. Nature Medicine, 29(7), pp. 1760-1774. (doi: 10.1038/s41591-023-02414-4) (PMID:37414897) (PMCID:PMC10353927)

Lindsay, S. L. , McCanney, G. A., Zhan, J., Scheld, M., Sherrard Smith, R., Goodyear, C. S. , Yates, E. A., Kipp, M., Turnbull, J. E. and Barnett, S. C. (2023) Low sulfated heparan sulfate mimetic differentially affects repair in immune-mediated and toxin-induced experimental models of demyelination. Glia, 71(7), pp. 1683-1698. (doi: 10.1002/glia.24363) (PMID:36945189)

Najm, A. , Goodyear, C. S. , McInnes, I. B. and Siebert, S. (2023) Phenotypic heterogeneity in psoriatic arthritis: towards tissue pathology-based therapy. Nature Reviews Rheumatology, 19, pp. 153-165. (doi: 10.1038/s41584-022-00874-5) (PMID:36596924)

Malcolm, J. et al. (2023) C-terminal citrullinated peptide alters antigen-specific APC:T cell interactions leading to breach of immune tolerance. Journal of Autoimmunity, 135, 102994. (doi: 10.1016/j.jaut.2023.102994) (PMID:36706535)

Riedlova, P. , Sood, S., Goodyear, C. S. and Ansalone, C. (2023) Differentiation of functional osteoclasts from human peripheral blood CD14+ monocytes. Journal of Visualized Experiments(191), e64698. (doi: 10.3791/64698) (PMID:36779608)

Nyirenda, M. H., Nijjar, J. S., Frleta-Gilchrist, M., Gilchrist, D. S., Porter, D., Siebert, S. , Goodyear, C. S. and McInnes, I. B. (2023) JAK inhibitors disrupt T cell-induced proinflammatory macrophage activation. RMD Open, 9(1), e002671. (doi: 10.1136/rmdopen-2022-002671) (PMID:36599629) (PMCID:PMC9815080)

2022

Huesa, C. et al. (2022) Moderate exercise protects against joint disease in a murine model of osteoarthritis. Frontiers in Physiology, 13, 1065278. (doi: 10.3389/fphys.2022.1065278) (PMID:36545287) (PMCID:PMC9760924)

Thümmler, K. , Williams, M. T.S., Kitson, S., Sood, S., Akbar, M., Cole, J. J., Goodyear, C. S. , Hunter, E. and Soutar, R. (2022) Targeting 3D chromosomal architecture at the RANK loci to suppress myeloma-driven osteoclastogenesis. OncoImmunology, 11(1), 2104070. (doi: 10.1080/2162402X.2022.2104070) (PMID:35936985) (PMCID:PMC9348127)

Gurke, R. et al. (2022) Omics and multi-omics analysis for the early identification and improved outcome of patients with psoriatic arthritis. Biomedicines, 10(10), 2387. (doi: 10.3390/biomedicines10102387) (PMID:36289648) (PMCID:PMC9598654)

Mortensen, J. H. et al. (2022) A specific calprotectin neo-epitope (CPa9-HNE) in serum from inflammatory bowel disease patients is associated with neutrophil activity and endoscopic severity. Journal of Crohn's and Colitis, 16(9), pp. 1447-1460. (doi: 10.1093/ecco-jcc/jjac047) (PMID:35304895) (PMCID:PMC9455793)

Kelly, L., McGrath, S., Rodgers, L., McCall, K., Tulunay Virlan, A. , Dempsey, F., Crichton, S. and Goodyear, C. S. (2022) Annexin-A1: the culprit or the solution? Immunology, 166(1), pp. 2-16. (doi: 10.1111/imm.13455) (PMID:35146757)

Lindsay, S. L. , Molęda, A. M., MacLellan, L. M., Keh, S. M., McElroy, D. E., Linington, C. , Goodyear, C. S. and Barnett, S. C. (2022) Human olfactory mesenchymal stromal cell transplantation ameliorates experimental autoimmune encephalomyelitis revealing an inhibitory role for IL16 on myelination. Acta Neuropathologica Communications, 10, 12. (doi: 10.1186/s40478-022-01316-9) (PMID:35093166) (PMCID:PMC8800340)

Degboe, Y., Sunzini, F., Sood, S., Bozec, A., Sokolova, M. V., Zekovic, A., McInnes, I. B. , Schett, G. and Goodyear, C. S. (2022) Apremilast inhibits inflammatory osteoclastogenesis. Rheumatology, 61(1), pp. 452-461. (doi: 10.1093/rheumatology/keab315) (PMID:33788924)

Morrow, A. et al. (2022) Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise—CISCO-21. Trials, 23, 660. (doi: 10.1186/s13063-022-06632-y) (PMID:35971155) (PMCID:PMC9376905)

2021

Clayton, S. A. et al. (2021) Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48. Science Advances, 7(50), eabl5182. (doi: 10.1126/sciadv.abl5182) (PMID:34878835)

Kok, F. O., Wang, H., Riedlova, P. , Goodyear, C. S. and Carmody, R. J. (2021) Defining the structure of the NF-ĸB pathway in human immune cells using quantitative proteomic data. Cellular Signalling, 88, 110154. (doi: 10.1016/j.cellsig.2021.110154) (PMID:34562606)

Kennedy, J. W., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P. S., Meek, D. R. M., Goodyear, C. S. and Dalby, M. J. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. Scientific Reports, 11, 22741. (doi: 10.1038/s41598-021-02139-9)

Cole, J. J., Faydaci, B. A., Mcguinness, D. , Shaw, R., Maciewicz, R. A., Robertson, N. A. and Goodyear, C. S. (2021) Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. BMC Bioinformatics, 22(1), 411. (doi: 10.1186/s12859-021-04321-2)

Cole, J. J. et al. (2021) No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing. Translational Psychiatry, 11, 404. (doi: 10.1038/s41398-021-01506-4) (PMID:34294682) (PMCID:PMC8298604)

Lindsay, S. , Molęda, A., Maclellan, L., Linington, C. , Goodyear, C. and Barnett, S. (2021) Severe experimental autoimmune encephalomyelitis (EAE) is ameliorated by human olfactory-derived mesenchymal stromal cell transplantation revealing a role for IL-16. XV European Meeting on Glial Cells in Health and Disease, 5-9 July 2021. E430-E432. (doi: 10.1002/glia.24036)

Ntala, C. et al. (2021) Analysis of prostate cancer tumor microenvironment identifies reduced stromal CD4 effector T-cell infiltration in tumors with pelvic nodal metastasis. European Urology Open Science, 29, pp. 19-29. (doi: 10.1016/j.euros.2021.05.001) (PMID:34337530) (PMCID:PMC8317840)

Sherrard Smith, R., Lindsay, S.L. , Goodyear, C. , Turnbull, J. and Barnett, S.C. (2021) Heparan Sulphate mimetics as a therapeutic for central nervous system repair. XV European Meeting on Glial Cells in Health and Disease, 5-9 July 2021. E513-E514. (doi: 10.1002/glia.24036)

Ansalone, C. , Cole, J., Chilaka, S., Sunzini, F., Sood, S., Robertson, J., Siebert, S. , McInnes, I. B. and Goodyear, C. (2021) TNF is a homeostatic regulator of distinct epigenetically primed human osteoclast precursors. Annals of the Rheumatic Diseases, 80(6), pp. 748-757. (doi: 10.1136/annrheumdis-2020-219262) (PMID:33692019) (PMCID:PMC8142443)

Kästele, V. et al. (2021) Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection. Mucosal Immunology, 14(3), pp. 717-727. (doi: 10.1038/s41385-020-00366-3) (PMID:33414524) (PMCID:PMC8075955)

Mooney, L., Goodyear, C. S. , Chandra, T., Kirschner, K. , Copland, M. , Petrie, M. C. and Lang, N. N. (2021) Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure. Clinical Science, 135(7), pp. 991-1007. (doi: 10.1042/CS20200306) (PMID:33861346) (PMCID:PMC8055963)

Farthing, A. G. et al. (2021) Sepsis: when a simple infection becomes deadly. Frontiers for Young Minds, 9, 639681. (doi: 10.3389/frym.2021.639681)

Pugh, D. et al. (2021) Large-vessel vasculitis. Nature Reviews Disease Primers, 7, 93. (doi: 10.1038/s41572-021-00327-5) (PMID:34992251)

Rayner, F. et al. (2021) BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study. BMC Rheumatology, 5, 22. (doi: 10.1186/s41927-021-00194-3) (PMID:34275488) (PMCID:PMC8286860)

2020

Najm, A. et al. (2020) MicroRNA‐17‐5p reduces inflammation and bone erosions in mice with collagen‐induced arthritis and directly targets the JAK/STAT pathway in rheumatoid arthritis fibroblast‐like synoviocytes. Arthritis and Rheumatology, 72(12), pp. 2030-2039. (doi: 10.1002/art.41441) (PMID:32683798)

McIntyre, C. L., Monin, L., Rop, J. C., Otto, T. D. , Goodyear, C. S. , Hayday, A. C. and Morrison, V. L. (2020) β2 integrins differentially regulate γδ T cell subset thymic development and peripheral maintenance. Proceedings of the National Academy of Sciences of the United States of America, 117(36), pp. 22367-22377. (doi: 10.1073/pnas.1921930117) (PMID:32848068)

Vinci, .C. et al. (2020) Immunoglobulin A antibodies to oxidized collagen type II as a potential biomarker for the stratification of spondyloarthritis from rheumatoid arthritis. Scandinavian Journal of Rheumatology, 49(4), pp. 281-291. (doi: 10.1080/03009742.2020.1713395) (PMID:32314641)

Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)

Rodgers, L. C., Cole, J., Rattigan, K. M., Barrett, M. P. , Kurian, N., McInnes, I. B. and Goodyear, C. S. (2020) The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion. Rheumatology, 59(4), pp. 869-878. (doi: 10.1093/rheumatology/kez378) (PMID:31497857)

Rios, F. J. et al. (2020) Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis. Cardiovascular Research, 116(3), pp. 721-735. (doi: 10.1093/cvr/cvz164) (PMID:31250885) (PMCID:PMC7252442)

Loveridge, C. J. et al. (2020) BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene, 39, pp. 1797-1806. (doi: 10.1038/s41388-019-1106-x) (PMID:31740786) (PMCID:PMC7033044)

2019

McCulloch, K., Huesa, C., Dunning, L., Litherland, G. J., Van 'T Hof, R. J., Lockhart, J. C. and Goodyear, C. S. (2019) Accelerated post traumatic osteoarthritis in a dual injury murine model. Osteoarthritis and Cartilage, 27(12), pp. 1800-1810. (doi: 10.1016/j.joca.2019.05.027) (PMID:31283983)

Westerhof, L. M. , McGuire, K., MacLellan, L., Flynn, A., Gray, J. I., Thomas, M., Goodyear, C. S. and MacLeod, M. K.L. (2019) Multifunctional cytokine production reveals functional superiority of memory CD4 T cells. European Journal of Immunology, 49(11), pp. 2019-2029. (doi: 10.1002/eji.201848026) (PMID:31177549) (PMCID:PMC6900100)

Cossarizza, A. et al. (2019) Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology, 49(10), pp. 1457-1973. (doi: 10.1002/eji.201970107) (PMID:31633216)

2018

Tom, B. D.M., Symmons, D. and RA-MAP Consortium:, (2018) Novel methodology to discern predictors of remission and patterns of disease activity over time using rheumatoid arthritis clinical trials data. RMD Open, 4(2), e000721. (doi: 10.1136/rmdopen-2018-000721) (PMID:30487994) (PMCID:PMC6241979)

Ulloa-Morales, A. J., Goodyear, C. S. and Silverman, G. J. (2018) Essential domain-dependent roles within soluble IgG for in vivo superantigen properties of staphylococcal protein A: resolving the B-cell superantigen paradox. Frontiers in Immunology, 9, 2011. (doi: 10.3389/fimmu.2018.02011) (PMID:30283436) (PMCID:PMC6156153)

Rattigan, K. M., Pountain, A. W. , Regnault, C., Achcar, F. , Vincent, I. M. , Goodyear, C. S. and Barrett, M. P. (2018) Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli. PLoS ONE, 13(3), e0194126. (doi: 10.1371/journal.pone.0194126) (PMID:29538444) (PMCID:PMC5851634)

Carini, C., Hunter, E., Scottish Early Rheumatoid Arthritis Inception cohort, , Ramadass, A. S., Green, J., Akoulitchev, A., McInnes, I. B. and Goodyear, C. S. (2018) Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis. Journal of Translational Medicine, 16(1), 18. (doi: 10.1186/s12967-018-1387-9) (PMID:29378619) (PMCID:PMC5789697)

2017

Cope, A. P. et al. (2017) The RA-MAP Consortium: a working model for academia-industry collaboration. Nature Reviews Rheumatology, 14, pp. 53-60. (doi: 10.1038/nrrheum.2017.200) (PMID:29213124)

Cossarizza, A. et al. (2017) Guidelines for the use of flow cytometry and cell sorting in immunological studies. European Journal of Immunology, 47(10), pp. 1584-1797. (doi: 10.1002/eji.201646632) (PMID:29023707)

Marton, N. et al. (2017) Extracellular vesicles regulate the human osteoclastogenesis: divergent roles in discrete inflammatory arthropathies. Cellular and Molecular Life Sciences, 74(19), pp. 3599-3611. (doi: 10.1007/s00018-017-2535-8) (PMID:28493076)

Ansalone, C. , Utriainen, L., Milling, S. and Goodyear, C. S. (2017) Role of gut inflammation in altering the monocyte compartment and its osteoclastogenic potential in HLA–B27–transgenic rats. Arthritis and Rheumatology, 69(9), pp. 1807-1815. (doi: 10.1002/art.40154) (PMID:28511292)

Lindsay, S.L. , McElroy, D.E., Goodyear, C.S. and Barnett, S.C. (2017) Severe experimental autoimmune encephalomyelitis (EAE) is ameliorated by human olfactory-derived mesenchymal stromal cell transplantation. XIII European Meeting on Glial Cells in Health and Disease, Edinburgh, Scotland, 08-11 Jul 2017. E516. (doi: 10.1002/glia.23157)

2016

Huesa, C. et al. (2016) Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology. Annals of the Rheumatic Diseases, 75(11), pp. 1989-1997. (doi: 10.1136/annrheumdis-2015-208268) (PMID:26698846) (PMCID:PMC5099200)

Ahmed, A., Hollan, I., Curran, S. A., Kitson, S. M., Riggio, M. P. , Mikkelsen, K., Almdahl, S. M., Aukrust, P., McInnes, I. B. and Goodyear, C. S. (2016) Rheumatoid arthritis patients have a pro-atherogenic cytokine microenvironment in the aortic adventitia. Arthritis and Rheumatology, 68(6), pp. 1361-1366. (doi: 10.1002/art.39574) (PMID:26749303) (PMCID:PMC4920270)

Herrington, F. D., Carmody, R. J. and Goodyear, C. S. (2016) Modulation of NF-κB signaling as a therapeutic target in autoimmunity. Journal of Biomolecular Screening, 21(3), pp. 223-242. (doi: 10.1177/1087057115617456) (PMID:26597958)

2015

Williams, M. T., Thümmler, K., Kitson, S., Soutar, R. and Goodyear, C. S. (2015) 3011 Fc Receptor Targeting Reduces Bone Disease in a Pre-Clinical Model of Multiple Myeloma. 57th ASH Annual Meeting and Exposition, Orange County, FL, USA, 4-8 Dec 2015.

Ansalone, C. , Utriainen, L., Milling, S. W.F. and Goodyear, C. S. (2015) Gut Inflammation in HLA-B27 Transgenic Rats Alters the Monocyte Compartment and Its Osteoclastogenic Potential. ACR/ARHP Annual Meeting, San Francisco, CA, USA, 6-11 Nov 2015.

Ansalone, C. , Milling, S. and Goodyear, C. S. (2015) HLA-B27 Over-Expression in Rats Alters Central and Peripheral Monocyte Populations. 35th European Workshop for Rheumatology Research, Budapest, Hungary, 05-07 Mar 2015. (doi: 10.1136/annrheumdis-2015-207259.31)

Hansell, C. A., MacLellan, L. M., Oldham, R. S., Doonan, J., Chapple, K. J., Anderson, E. J., Linington, C. , McInnes, I. B. , Nibbs, R. J. and Goodyear, C. S. (2015) The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens. Immunology and Cell Biology, 93(2), pp. 167-176. (doi: 10.1038/icb.2014.90) (PMID:25348934) (PMCID:PMC4340511)

2014

Colombo, M. et al. (2014) Notch signaling drives multiple myeloma induced osteoclastogenesis. Oncotarget, 5(21), pp. 10393-10406. (doi: 10.18632/oncotarget.2084) (PMID:25257302) (PMCID:PMC4279381)

Curran, S. A. et al. (2014) Bacteria in the adventitia of cardiovascular disease patients with and without rheumatoid arthritis. PLoS ONE, 9(5), e98627. (doi: 10.1371/journal.pone.0098627) (PMID:24874661) (PMCID:PMC4038603)

2013

Reindl, M. et al. (2013) Antibodies to heteromeric glycolipid complexes in Guillain-Barré syndrome. PLoS ONE, 8(12), e82337. (doi: 10.1371/journal.pone.0082337) (PMID:24358172) (PMCID:PMC3864991)

Willison, H.J. and Goodyear, C.S. (2013) Glycolipid antigens and autoantibodies in autoimmune neuropathies. Trends in Immunology, 34(9), pp. 453-459. (doi: 10.1016/j.it.2013.05.001)

Hollan, I. et al. (2013) Cardiovascular disease in autoimmune rheumatic diseases. Autoimmunity Reviews, 12(10), pp. 1004-1015. (doi: 10.1016/j.autrev.2013.03.013)

Galban-Horcajo, F., Fitzpatrick, A.M., Hutton, A.J., Dunn, S.M., Kalna, G., Brennan, K.M., Rinaldi, S., Yu, R.K., Goodyear, C.S. and Willison, H.J. (2013) Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy. European Journal of Neurology, 20(1), pp. 62-70. (doi: 10.1111/j.1468-1331.2012.03767.x)

Dunne, K.A. et al. (2013) Increased S-nitrosylation and proteasomal degradation of caspase-3 during infection contribute to the persistence of adherent invasive escherichia coli (AIEC) in immune cells. PLoS ONE, 8(7), e68386. (doi: 10.1371/journal.pone.0068386) (PMID:23861899) (PMCID:PMC3701656)

2012

Jiang, H.-R. et al. (2012) IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages. European Journal of Immunology, 42(7), pp. 1804-1814. (doi: 10.1002/eji.201141947)

Huizinga, R. et al. (2012) Sialylation of campylobacter jejuni lipo-oligosaccharides: impact on phagocytosis and cytokine production in mice. PLoS ONE, 7(3), e34416. (doi: 10.1371/journal.pone.0034416) (PMID:22470569) (PMCID:PMC3314637)

2011

MacLellan, L. M., Montgomery, J., Sugiyama, F., Kitson, S. M., Thümmler, K. , Silverman, G. J., Beers, S. A., Nibbs, R. J.B. , McInnes, I. B. and Goodyear, C. S. (2011) Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice. Arthritis and Rheumatism, 63(12), pp. 3897-3907. (doi: 10.1002/art.30629) (PMID:22127707) (PMCID:PMC3598489)

Hansell, C. A. H., Schiering, C., Kinstrie, R., Ford, L., Bordon, Y., McInnes, I. B. , Goodyear, C. S. and Nibbs, R. J.B. (2011) Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice. Blood, 117(20), pp. 5413-5424. (doi: 10.1182/blood-2010-11-317115) (PMID:21450903) (PMCID:PMC3188399)

Komai-Koma, M., Gilchrist, D. S., McKenzie, A. N. J., Goodyear, C. S. , Xu, D. and Liew, F. Y. (2011) IL-33 activates B1 cells and exacerbates contact sensitivity. Journal of Immunology, 186(4), pp. 2584-2591. (doi: 10.4049/jimmunol.1002103)

Brennan, K.M. et al. (2011) Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis. Journal of Neuroimmunology, 238(1-2), pp. 87-95. (doi: 10.1016/j.jneuroim.2011.08.002)

2009

Greenshields, K.N. et al. (2009) The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice. Journal of Clinical Investigation, 119(3), pp. 595-610. (doi: 10.1172/JCI37338)

Jiang, H., Al Rasebi, Z., Mensah-Brown, E., Shahin, A., Xu, D., Goodyear, C. , Fukada, S., Liu, F., Liew, F. and Lukic, M. (2009) Galectin-3 Deficiency Reduces the Severity of Experimental Autoimmune Encephalomyelitis. Journal of Immunology, 182(2), pp. 1167-1173.

Chen, Y. et al. (2009) Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. Journal of Immunology, 183(2), pp. 1346-1359. (doi: 10.4049/jimmunol.0900948)

Rinaldi, S., Brennan, K., Goodyear, C. , O'Leary, C., Schiavo, G., Crocker, P. and Willison, H. (2009) Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays. Glycobiology, 19(7), pp. 789-796. (doi: 10.1093/glycob/cwp049)

2008

Silverman, G.J., Srikrishnan, R., Germar, K., Goodyear, C.S. , Andrews, K.A., Ginzler, E.M. and Tsao, B.P. (2008) Genetic imprinting of autoantibody repertoires in systemic lupus erythematosus patients. Clinical and Experimental Immunology, 153(1), pp. 102-116. (doi: 10.1111/j.1365-2249.2008.03680.x)

Townson, K., Speak, A., Greenshields, K., Goodyear, C. , Willison, H. and Platt, F. (2008) Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury. Journal of Neuroimmunology, 203(1), pp. 33-38. (doi: 10.1016/j.jneuroim.2008.06.033)

2007

Goodyear, C. , Corr, M., Sugiyama, F., Boyle, D. and Silverman, G. (2007) Cutting edge: Bim is required for superantigen-mediated B cell death. Journal of Immunology, 178, pp. 2636-2640.

Silverman, G., Khanna, S., Goodyear, C. , Park, Y., Corr, M. and Chen, Y. (2007) Natural antibody regulation of innate immunity: Protection from inflammatory arthritis. Annals of the Rheumatic Diseases, 66, pp. 73-74.

2006

Goodyear, C. , Chen, Y., Sugiyama, F., Corr, M. and Silverman, G. (2006) Inhibition of autoimmune arthritis by a natural antibody that enhances apoptotic clearance. Arthritis and Rheumatism, 54(9), S355-S355.

Goodyear, C. and Silverman, G. (2006) A microbial toxin forms immune complexes that co-opts cellular Fc gamma R to induce B-cell apoptotic death. Journal of Immunology, 176, S76-S76.

Goodyear, C. , Sugiyama, F. and Silverman, G. (2006) Temporal and dose-dependent relationships between in vivo B cell receptor-targeted proliferation and deletion-induced by a microbial B cell toxin. Journal of Immunology, 176(4), pp. 2262-2271.

Silverman, G. and Goodyear, C. (2006) Confounding B-cell defences: lessons from a staphylococcal superantigen. Nature Reviews Immunology, 6(6), pp. 465-475.

Silverman, G., Goodyear, C. , Germar, K., Kono, D. and Chen, Y. (2006) A therapeutic antibody that enhances apoptotic clearance blocks in vivo TLR-induced cellular activation, and pro-inflammatory cytokine and chemokine production. Arthritis and Rheumatism, 54(9), S450-S450.

2005

Finlay, W., deVore, N., Dobrovolskaia, E., Gam, A., Goodyear, C. and Slater, J. (2005) Exploiting the avian immunoglobulin system to simplify the generation of recombinant antibodies to allergenic proteins. Clinical and Experimental Allergy, 35(8), pp. 1040-1048.

Goodyear, C. , Boyle, D. and Silverman, G. (2005) Secretion of BAFF by fibroblast-like synoviocytes from rheumatoid arthritis biopsies attenuates B-cell depletion by rituximab. Arthritis and Rheumatism, 52(9), S290-S290.

Goodyear, C. and Silverman, G. (2005) B cell superantigens: a microbe's answer to innate-like B cells and natural antibodies. Springer Seminars in Immunopathology, 26(4), pp. 463-484.

Goodyear, C. , Sugiyama, F. and Silverman, G. (2005) Mature splenic B-cell subsets are discordant in their dependence on Birn for in vivo BCR-mediated cell death. FASEB Journal, 19(4), A953-A954.

Silverman, G., Goodyear, C. and Siegel, D. (2005) On the mechanism of staphylococcal protein A immunomodulation. Transfusion, 45(2), pp. 274-280.

Silverman, G., Haraldsson, M., Goodyear, C. , Chen, Y. and Kono, D. (2005) Passive monoclonal antibody treatment that enhances clearance of apoptotic particles improves survival in lupus-prone (NZWxBXSB)F1 mice. Arthritis and Rheumatism, 52(9), S699-S700.

2004

Anderson, J., Mueller, J., Rosengren, S., Boyle, D., Schaner, P., Cannon, S., Goodyear, C. and Hoffman, H. (2004) Structural, expression, and evolutionary analysis of mouse CIASI. Gene, 338(1), pp. 25-34.

Goodyear, C. , Narita, M. and Silverman, G. (2004) In vivo V-L-targeted activation-induced apoptotic supraclonal deletion by a microbial B cell toxin. Journal of Immunology, 172(5), pp. 2870-2877.

Goodyear, C. and Silverman, G. (2004) Staphylococcal toxin induced preferential and prolonged in vivo deletion of innate-like B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America, 101(31), pp. 11392-11397. (doi: 10.1073/pnas.0404382101)

2003

Binder, C., Horkko, S., Dewan, A., Chang, M., Kieu, E., Goodyear, C. , Shaw, P., Palinski, W., Witztum, J. and Silverman, G. (2003) Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nature Medicine, 9(6), pp. 736-743.

Goodyear, C. and Silverman, G. (2003) Characterization of a pro-apoptotic natural Ligand-BCR co-complex. FASEB Journal, 17(7), C261-C261.

Goodyear, C. and Silverman, G. (2003) Death by a B cell superantigen: In vivo V-H-targeted apoptotic supraclonal B cell deletion by a staphylococcal toxin. Journal of Experimental Medicine, 197(9), pp. 1125-1139.

Shaw, P., Goodyear, C. , Chang, M., Witztum, J. and Silverman, G. (2003) The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells. Journal of Immunology, 170(12), pp. 6151-6157.

2002

Finlay, W., Goodyear, C. and Slater, J. (2002) Analysis of IgE heavy chain sequences from a small volume of peripheral blood from a mildly atopic individual. Journal of Allergy and Clinical Immunology, 109(1), S112-S112.

Goodyear, C.S. and Silverman, G.J. (2002) Phage-display approaches for the study of protein-protein interactions. In: Golemis, E. (ed.) Protein-Protein Interactions: A Molecular Cloning Manual. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, USA, pp. 143-166. ISBN 9780879696047

Silverman, G. and Goodyear, C. (2002) A model B-cell superantigen and the immunobiology of B lymphocytes. Clinical Immunology, 102(2), pp. 117-134.

Silverman, G., Jenne, K. and Goodyear, C. (2002) In vivo VH targeted B-cell apoptotic deletion in nice and non-human primates. FASEB Journal, 16(4), A310-A310.

2001

Goodyear, C. and Silverman, G. (2001) Mechanisms of B-cell superantigen-mediated activation-induced cell death. FASEB Journal, 15(4), A694-A694.

O'Hanlon, G.M. et al. (2001) Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal. Brain, 124(5), pp. 893-906. (doi: 10.1093/brain/124.5.893)

2000

Bullens, R.W.M., O'Hanlon, G.M., Goodyear, C.S. , Molenaar, P.C., Conner, J., Willison, H.J. and Plomp, J.J. (2000) Anti-GQ1b antibodies and evoked acetylcholine release at mouse motor endplates. Muscle and Nerve, 23(7), pp. 1035-1043. (doi: 10.1002/1097-4598(200007)23:7<1035::AID-MUS5>3.0.CO;2-R)

1999

Goodyear, C.S. , O'Hanlon, G.M., Plomp, J.J., Wagner, E.R., Cochrane, L., Bullens, R.W.M., Molenaar, P.C., Conner, J. and Willison, H.J. (1999) Monoclonal antibodies raised against Guillain-Barr. Journal of Clinical Investigation, 104(6), pp. 697-708. (doi: 10.1172/JCI6837)

This list was generated on Sun Dec 8 06:36:02 2024 GMT.
Number of items: 109.

Articles

Colton, H. et al. (2024) Greater preservation of SARS‐CoV‐2 neutralising antibody responses following the ChAdOx1‐S (AZD1222) vaccine compared with mRNA vaccines in haematopoietic cell transplant recipients. British Journal of Haematology, (doi: 10.1111/bjh.19874) (PMID:39551718) (Early Online Publication)

Asghar, S., Litherland, G. J., Cole, J. J., McInnes, I. B. , Meek, R.M.D., Lockhart, J. C., Goodyear, C. S. and Crilly, A. (2024) Small extracellular vesicles derived from synovial fibroblasts contain distinct miRNA profiles and contribute to chondrocyte damage in osteoarthritis. Arthritis Research and Therapy, 26(1), 167. (doi: 10.1186/s13075-024-03398-3) (PMID:39342381)

Goodyear, C. S. et al. (2024) Immunogenicity of third dose COVID-19 vaccine strategies in patients who are immunocompromised with suboptimal immunity following two doses (OCTAVE-DUO): an open-label, multicentre, randomised, controlled, phase 3 trial. Lancet Rheumatology, 6(6), e339-e351. (doi: 10.1016/S2665-9913(24)00065-1) (PMID:38734019)

Jaffery, H. et al. (2023) IĸB Protein BCL3 as a controller of osteogenesis and bone health. Arthritis and Rheumatology, 75(12), 2148-2160-2148-2160. (doi: 10.1002/art.42639) (PMID:37410754)

FitzGerald, O. et al. (2023) Application of clinical and molecular profiling data to improve patient outcomes in psoriatic arthritis. Therapeutic Advances in Musculoskeletal Disease, 15, pp. 1-14. (doi: 10.1177/1759720x231192315) (PMID:37694182) (PMCID:PMC10492462)

Cole, S. et al. (2023) Differential regulation of IL-17A and IL-17F via STAT5 contributes to psoriatic disease. Journal of Allergy and Clinical Immunology, 152(3), pp. 783-798. (doi: 10.1016/j.jaci.2023.03.035) (PMID:37244461)

Ooms, A. et al. (2023) Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis. BMJ Open, 13(9), e078539. (doi: 10.1136/bmjopen-2023-078539) (PMID:37770264) (PMCID:PMC10546161)

Wing, E., Sutherland, C., Miles, K., Gray, D., Goodyear, C. S. , Otto, T. D. , Breusch, S., Cowan, G. and Gray, M. (2023) Double-negative-2 B cells are the major synovial plasma cell precursor in rheumatoid arthritis. Frontiers in Immunology, 14, 1241474. (doi: 10.3389/fimmu.2023.1241474) (PMID:37638026) (PMCID:PMC10450142)

Barnes, E. et al. (2023) SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease. Nature Medicine, 29(7), pp. 1760-1774. (doi: 10.1038/s41591-023-02414-4) (PMID:37414897) (PMCID:PMC10353927)

Lindsay, S. L. , McCanney, G. A., Zhan, J., Scheld, M., Sherrard Smith, R., Goodyear, C. S. , Yates, E. A., Kipp, M., Turnbull, J. E. and Barnett, S. C. (2023) Low sulfated heparan sulfate mimetic differentially affects repair in immune-mediated and toxin-induced experimental models of demyelination. Glia, 71(7), pp. 1683-1698. (doi: 10.1002/glia.24363) (PMID:36945189)

Najm, A. , Goodyear, C. S. , McInnes, I. B. and Siebert, S. (2023) Phenotypic heterogeneity in psoriatic arthritis: towards tissue pathology-based therapy. Nature Reviews Rheumatology, 19, pp. 153-165. (doi: 10.1038/s41584-022-00874-5) (PMID:36596924)

Malcolm, J. et al. (2023) C-terminal citrullinated peptide alters antigen-specific APC:T cell interactions leading to breach of immune tolerance. Journal of Autoimmunity, 135, 102994. (doi: 10.1016/j.jaut.2023.102994) (PMID:36706535)

Riedlova, P. , Sood, S., Goodyear, C. S. and Ansalone, C. (2023) Differentiation of functional osteoclasts from human peripheral blood CD14+ monocytes. Journal of Visualized Experiments(191), e64698. (doi: 10.3791/64698) (PMID:36779608)

Nyirenda, M. H., Nijjar, J. S., Frleta-Gilchrist, M., Gilchrist, D. S., Porter, D., Siebert, S. , Goodyear, C. S. and McInnes, I. B. (2023) JAK inhibitors disrupt T cell-induced proinflammatory macrophage activation. RMD Open, 9(1), e002671. (doi: 10.1136/rmdopen-2022-002671) (PMID:36599629) (PMCID:PMC9815080)

Huesa, C. et al. (2022) Moderate exercise protects against joint disease in a murine model of osteoarthritis. Frontiers in Physiology, 13, 1065278. (doi: 10.3389/fphys.2022.1065278) (PMID:36545287) (PMCID:PMC9760924)

Thümmler, K. , Williams, M. T.S., Kitson, S., Sood, S., Akbar, M., Cole, J. J., Goodyear, C. S. , Hunter, E. and Soutar, R. (2022) Targeting 3D chromosomal architecture at the RANK loci to suppress myeloma-driven osteoclastogenesis. OncoImmunology, 11(1), 2104070. (doi: 10.1080/2162402X.2022.2104070) (PMID:35936985) (PMCID:PMC9348127)

Gurke, R. et al. (2022) Omics and multi-omics analysis for the early identification and improved outcome of patients with psoriatic arthritis. Biomedicines, 10(10), 2387. (doi: 10.3390/biomedicines10102387) (PMID:36289648) (PMCID:PMC9598654)

Mortensen, J. H. et al. (2022) A specific calprotectin neo-epitope (CPa9-HNE) in serum from inflammatory bowel disease patients is associated with neutrophil activity and endoscopic severity. Journal of Crohn's and Colitis, 16(9), pp. 1447-1460. (doi: 10.1093/ecco-jcc/jjac047) (PMID:35304895) (PMCID:PMC9455793)

Kelly, L., McGrath, S., Rodgers, L., McCall, K., Tulunay Virlan, A. , Dempsey, F., Crichton, S. and Goodyear, C. S. (2022) Annexin-A1: the culprit or the solution? Immunology, 166(1), pp. 2-16. (doi: 10.1111/imm.13455) (PMID:35146757)

Lindsay, S. L. , Molęda, A. M., MacLellan, L. M., Keh, S. M., McElroy, D. E., Linington, C. , Goodyear, C. S. and Barnett, S. C. (2022) Human olfactory mesenchymal stromal cell transplantation ameliorates experimental autoimmune encephalomyelitis revealing an inhibitory role for IL16 on myelination. Acta Neuropathologica Communications, 10, 12. (doi: 10.1186/s40478-022-01316-9) (PMID:35093166) (PMCID:PMC8800340)

Degboe, Y., Sunzini, F., Sood, S., Bozec, A., Sokolova, M. V., Zekovic, A., McInnes, I. B. , Schett, G. and Goodyear, C. S. (2022) Apremilast inhibits inflammatory osteoclastogenesis. Rheumatology, 61(1), pp. 452-461. (doi: 10.1093/rheumatology/keab315) (PMID:33788924)

Morrow, A. et al. (2022) Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise—CISCO-21. Trials, 23, 660. (doi: 10.1186/s13063-022-06632-y) (PMID:35971155) (PMCID:PMC9376905)

Clayton, S. A. et al. (2021) Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48. Science Advances, 7(50), eabl5182. (doi: 10.1126/sciadv.abl5182) (PMID:34878835)

Kok, F. O., Wang, H., Riedlova, P. , Goodyear, C. S. and Carmody, R. J. (2021) Defining the structure of the NF-ĸB pathway in human immune cells using quantitative proteomic data. Cellular Signalling, 88, 110154. (doi: 10.1016/j.cellsig.2021.110154) (PMID:34562606)

Kennedy, J. W., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P. S., Meek, D. R. M., Goodyear, C. S. and Dalby, M. J. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. Scientific Reports, 11, 22741. (doi: 10.1038/s41598-021-02139-9)

Cole, J. J., Faydaci, B. A., Mcguinness, D. , Shaw, R., Maciewicz, R. A., Robertson, N. A. and Goodyear, C. S. (2021) Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts. BMC Bioinformatics, 22(1), 411. (doi: 10.1186/s12859-021-04321-2)

Cole, J. J. et al. (2021) No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing. Translational Psychiatry, 11, 404. (doi: 10.1038/s41398-021-01506-4) (PMID:34294682) (PMCID:PMC8298604)

Ntala, C. et al. (2021) Analysis of prostate cancer tumor microenvironment identifies reduced stromal CD4 effector T-cell infiltration in tumors with pelvic nodal metastasis. European Urology Open Science, 29, pp. 19-29. (doi: 10.1016/j.euros.2021.05.001) (PMID:34337530) (PMCID:PMC8317840)

Ansalone, C. , Cole, J., Chilaka, S., Sunzini, F., Sood, S., Robertson, J., Siebert, S. , McInnes, I. B. and Goodyear, C. (2021) TNF is a homeostatic regulator of distinct epigenetically primed human osteoclast precursors. Annals of the Rheumatic Diseases, 80(6), pp. 748-757. (doi: 10.1136/annrheumdis-2020-219262) (PMID:33692019) (PMCID:PMC8142443)

Kästele, V. et al. (2021) Intestinal-derived ILCs migrating in lymph increase IFNγ production in response to Salmonella Typhimurium infection. Mucosal Immunology, 14(3), pp. 717-727. (doi: 10.1038/s41385-020-00366-3) (PMID:33414524) (PMCID:PMC8075955)

Mooney, L., Goodyear, C. S. , Chandra, T., Kirschner, K. , Copland, M. , Petrie, M. C. and Lang, N. N. (2021) Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure. Clinical Science, 135(7), pp. 991-1007. (doi: 10.1042/CS20200306) (PMID:33861346) (PMCID:PMC8055963)

Farthing, A. G. et al. (2021) Sepsis: when a simple infection becomes deadly. Frontiers for Young Minds, 9, 639681. (doi: 10.3389/frym.2021.639681)

Pugh, D. et al. (2021) Large-vessel vasculitis. Nature Reviews Disease Primers, 7, 93. (doi: 10.1038/s41572-021-00327-5) (PMID:34992251)

Rayner, F. et al. (2021) BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study. BMC Rheumatology, 5, 22. (doi: 10.1186/s41927-021-00194-3) (PMID:34275488) (PMCID:PMC8286860)

Najm, A. et al. (2020) MicroRNA‐17‐5p reduces inflammation and bone erosions in mice with collagen‐induced arthritis and directly targets the JAK/STAT pathway in rheumatoid arthritis fibroblast‐like synoviocytes. Arthritis and Rheumatology, 72(12), pp. 2030-2039. (doi: 10.1002/art.41441) (PMID:32683798)

McIntyre, C. L., Monin, L., Rop, J. C., Otto, T. D. , Goodyear, C. S. , Hayday, A. C. and Morrison, V. L. (2020) β2 integrins differentially regulate γδ T cell subset thymic development and peripheral maintenance. Proceedings of the National Academy of Sciences of the United States of America, 117(36), pp. 22367-22377. (doi: 10.1073/pnas.1921930117) (PMID:32848068)

Vinci, .C. et al. (2020) Immunoglobulin A antibodies to oxidized collagen type II as a potential biomarker for the stratification of spondyloarthritis from rheumatoid arthritis. Scandinavian Journal of Rheumatology, 49(4), pp. 281-291. (doi: 10.1080/03009742.2020.1713395) (PMID:32314641)

Daly, R. et al. (2020) Changes in plasma itaconate elevation in early rheumatoid arthritis patients elucidates disease activity associated macrophage activation. Metabolites, 10(6), 241. (doi: 10.3390/metabo10060241) (PMID:32531990) (PMCID:PMC7344783)

Rodgers, L. C., Cole, J., Rattigan, K. M., Barrett, M. P. , Kurian, N., McInnes, I. B. and Goodyear, C. S. (2020) The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion. Rheumatology, 59(4), pp. 869-878. (doi: 10.1093/rheumatology/kez378) (PMID:31497857)

Rios, F. J. et al. (2020) Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis. Cardiovascular Research, 116(3), pp. 721-735. (doi: 10.1093/cvr/cvz164) (PMID:31250885) (PMCID:PMC7252442)

Loveridge, C. J. et al. (2020) BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration. Oncogene, 39, pp. 1797-1806. (doi: 10.1038/s41388-019-1106-x) (PMID:31740786) (PMCID:PMC7033044)

McCulloch, K., Huesa, C., Dunning, L., Litherland, G. J., Van 'T Hof, R. J., Lockhart, J. C. and Goodyear, C. S. (2019) Accelerated post traumatic osteoarthritis in a dual injury murine model. Osteoarthritis and Cartilage, 27(12), pp. 1800-1810. (doi: 10.1016/j.joca.2019.05.027) (PMID:31283983)

Westerhof, L. M. , McGuire, K., MacLellan, L., Flynn, A., Gray, J. I., Thomas, M., Goodyear, C. S. and MacLeod, M. K.L. (2019) Multifunctional cytokine production reveals functional superiority of memory CD4 T cells. European Journal of Immunology, 49(11), pp. 2019-2029. (doi: 10.1002/eji.201848026) (PMID:31177549) (PMCID:PMC6900100)

Cossarizza, A. et al. (2019) Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology, 49(10), pp. 1457-1973. (doi: 10.1002/eji.201970107) (PMID:31633216)

Tom, B. D.M., Symmons, D. and RA-MAP Consortium:, (2018) Novel methodology to discern predictors of remission and patterns of disease activity over time using rheumatoid arthritis clinical trials data. RMD Open, 4(2), e000721. (doi: 10.1136/rmdopen-2018-000721) (PMID:30487994) (PMCID:PMC6241979)

Ulloa-Morales, A. J., Goodyear, C. S. and Silverman, G. J. (2018) Essential domain-dependent roles within soluble IgG for in vivo superantigen properties of staphylococcal protein A: resolving the B-cell superantigen paradox. Frontiers in Immunology, 9, 2011. (doi: 10.3389/fimmu.2018.02011) (PMID:30283436) (PMCID:PMC6156153)

Rattigan, K. M., Pountain, A. W. , Regnault, C., Achcar, F. , Vincent, I. M. , Goodyear, C. S. and Barrett, M. P. (2018) Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli. PLoS ONE, 13(3), e0194126. (doi: 10.1371/journal.pone.0194126) (PMID:29538444) (PMCID:PMC5851634)

Carini, C., Hunter, E., Scottish Early Rheumatoid Arthritis Inception cohort, , Ramadass, A. S., Green, J., Akoulitchev, A., McInnes, I. B. and Goodyear, C. S. (2018) Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis. Journal of Translational Medicine, 16(1), 18. (doi: 10.1186/s12967-018-1387-9) (PMID:29378619) (PMCID:PMC5789697)

Cope, A. P. et al. (2017) The RA-MAP Consortium: a working model for academia-industry collaboration. Nature Reviews Rheumatology, 14, pp. 53-60. (doi: 10.1038/nrrheum.2017.200) (PMID:29213124)

Cossarizza, A. et al. (2017) Guidelines for the use of flow cytometry and cell sorting in immunological studies. European Journal of Immunology, 47(10), pp. 1584-1797. (doi: 10.1002/eji.201646632) (PMID:29023707)

Marton, N. et al. (2017) Extracellular vesicles regulate the human osteoclastogenesis: divergent roles in discrete inflammatory arthropathies. Cellular and Molecular Life Sciences, 74(19), pp. 3599-3611. (doi: 10.1007/s00018-017-2535-8) (PMID:28493076)

Ansalone, C. , Utriainen, L., Milling, S. and Goodyear, C. S. (2017) Role of gut inflammation in altering the monocyte compartment and its osteoclastogenic potential in HLA–B27–transgenic rats. Arthritis and Rheumatology, 69(9), pp. 1807-1815. (doi: 10.1002/art.40154) (PMID:28511292)

Huesa, C. et al. (2016) Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology. Annals of the Rheumatic Diseases, 75(11), pp. 1989-1997. (doi: 10.1136/annrheumdis-2015-208268) (PMID:26698846) (PMCID:PMC5099200)

Ahmed, A., Hollan, I., Curran, S. A., Kitson, S. M., Riggio, M. P. , Mikkelsen, K., Almdahl, S. M., Aukrust, P., McInnes, I. B. and Goodyear, C. S. (2016) Rheumatoid arthritis patients have a pro-atherogenic cytokine microenvironment in the aortic adventitia. Arthritis and Rheumatology, 68(6), pp. 1361-1366. (doi: 10.1002/art.39574) (PMID:26749303) (PMCID:PMC4920270)

Herrington, F. D., Carmody, R. J. and Goodyear, C. S. (2016) Modulation of NF-κB signaling as a therapeutic target in autoimmunity. Journal of Biomolecular Screening, 21(3), pp. 223-242. (doi: 10.1177/1087057115617456) (PMID:26597958)

Hansell, C. A., MacLellan, L. M., Oldham, R. S., Doonan, J., Chapple, K. J., Anderson, E. J., Linington, C. , McInnes, I. B. , Nibbs, R. J. and Goodyear, C. S. (2015) The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens. Immunology and Cell Biology, 93(2), pp. 167-176. (doi: 10.1038/icb.2014.90) (PMID:25348934) (PMCID:PMC4340511)

Colombo, M. et al. (2014) Notch signaling drives multiple myeloma induced osteoclastogenesis. Oncotarget, 5(21), pp. 10393-10406. (doi: 10.18632/oncotarget.2084) (PMID:25257302) (PMCID:PMC4279381)

Curran, S. A. et al. (2014) Bacteria in the adventitia of cardiovascular disease patients with and without rheumatoid arthritis. PLoS ONE, 9(5), e98627. (doi: 10.1371/journal.pone.0098627) (PMID:24874661) (PMCID:PMC4038603)

Reindl, M. et al. (2013) Antibodies to heteromeric glycolipid complexes in Guillain-Barré syndrome. PLoS ONE, 8(12), e82337. (doi: 10.1371/journal.pone.0082337) (PMID:24358172) (PMCID:PMC3864991)

Willison, H.J. and Goodyear, C.S. (2013) Glycolipid antigens and autoantibodies in autoimmune neuropathies. Trends in Immunology, 34(9), pp. 453-459. (doi: 10.1016/j.it.2013.05.001)

Hollan, I. et al. (2013) Cardiovascular disease in autoimmune rheumatic diseases. Autoimmunity Reviews, 12(10), pp. 1004-1015. (doi: 10.1016/j.autrev.2013.03.013)

Galban-Horcajo, F., Fitzpatrick, A.M., Hutton, A.J., Dunn, S.M., Kalna, G., Brennan, K.M., Rinaldi, S., Yu, R.K., Goodyear, C.S. and Willison, H.J. (2013) Antibodies to heteromeric glycolipid complexes in multifocal motor neuropathy. European Journal of Neurology, 20(1), pp. 62-70. (doi: 10.1111/j.1468-1331.2012.03767.x)

Dunne, K.A. et al. (2013) Increased S-nitrosylation and proteasomal degradation of caspase-3 during infection contribute to the persistence of adherent invasive escherichia coli (AIEC) in immune cells. PLoS ONE, 8(7), e68386. (doi: 10.1371/journal.pone.0068386) (PMID:23861899) (PMCID:PMC3701656)

Jiang, H.-R. et al. (2012) IL-33 attenuates EAE by suppressing IL-17 and IFN-γ production and inducing alternatively activated macrophages. European Journal of Immunology, 42(7), pp. 1804-1814. (doi: 10.1002/eji.201141947)

Huizinga, R. et al. (2012) Sialylation of campylobacter jejuni lipo-oligosaccharides: impact on phagocytosis and cytokine production in mice. PLoS ONE, 7(3), e34416. (doi: 10.1371/journal.pone.0034416) (PMID:22470569) (PMCID:PMC3314637)

MacLellan, L. M., Montgomery, J., Sugiyama, F., Kitson, S. M., Thümmler, K. , Silverman, G. J., Beers, S. A., Nibbs, R. J.B. , McInnes, I. B. and Goodyear, C. S. (2011) Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice. Arthritis and Rheumatism, 63(12), pp. 3897-3907. (doi: 10.1002/art.30629) (PMID:22127707) (PMCID:PMC3598489)

Hansell, C. A. H., Schiering, C., Kinstrie, R., Ford, L., Bordon, Y., McInnes, I. B. , Goodyear, C. S. and Nibbs, R. J.B. (2011) Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice. Blood, 117(20), pp. 5413-5424. (doi: 10.1182/blood-2010-11-317115) (PMID:21450903) (PMCID:PMC3188399)

Komai-Koma, M., Gilchrist, D. S., McKenzie, A. N. J., Goodyear, C. S. , Xu, D. and Liew, F. Y. (2011) IL-33 activates B1 cells and exacerbates contact sensitivity. Journal of Immunology, 186(4), pp. 2584-2591. (doi: 10.4049/jimmunol.1002103)

Brennan, K.M. et al. (2011) Lipid arrays identify myelin-derived lipids and lipid complexes as prominent targets for oligoclonal band antibodies in multiple sclerosis. Journal of Neuroimmunology, 238(1-2), pp. 87-95. (doi: 10.1016/j.jneuroim.2011.08.002)

Greenshields, K.N. et al. (2009) The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice. Journal of Clinical Investigation, 119(3), pp. 595-610. (doi: 10.1172/JCI37338)

Jiang, H., Al Rasebi, Z., Mensah-Brown, E., Shahin, A., Xu, D., Goodyear, C. , Fukada, S., Liu, F., Liew, F. and Lukic, M. (2009) Galectin-3 Deficiency Reduces the Severity of Experimental Autoimmune Encephalomyelitis. Journal of Immunology, 182(2), pp. 1167-1173.

Chen, Y. et al. (2009) Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. Journal of Immunology, 183(2), pp. 1346-1359. (doi: 10.4049/jimmunol.0900948)

Rinaldi, S., Brennan, K., Goodyear, C. , O'Leary, C., Schiavo, G., Crocker, P. and Willison, H. (2009) Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays. Glycobiology, 19(7), pp. 789-796. (doi: 10.1093/glycob/cwp049)

Silverman, G.J., Srikrishnan, R., Germar, K., Goodyear, C.S. , Andrews, K.A., Ginzler, E.M. and Tsao, B.P. (2008) Genetic imprinting of autoantibody repertoires in systemic lupus erythematosus patients. Clinical and Experimental Immunology, 153(1), pp. 102-116. (doi: 10.1111/j.1365-2249.2008.03680.x)

Townson, K., Speak, A., Greenshields, K., Goodyear, C. , Willison, H. and Platt, F. (2008) Glycosphingolipid depletion in PC12 cells using iminosugars protects neuronal membranes from anti-ganglioside antibody mediated injury. Journal of Neuroimmunology, 203(1), pp. 33-38. (doi: 10.1016/j.jneuroim.2008.06.033)

Goodyear, C. , Corr, M., Sugiyama, F., Boyle, D. and Silverman, G. (2007) Cutting edge: Bim is required for superantigen-mediated B cell death. Journal of Immunology, 178, pp. 2636-2640.

Silverman, G., Khanna, S., Goodyear, C. , Park, Y., Corr, M. and Chen, Y. (2007) Natural antibody regulation of innate immunity: Protection from inflammatory arthritis. Annals of the Rheumatic Diseases, 66, pp. 73-74.

Goodyear, C. , Chen, Y., Sugiyama, F., Corr, M. and Silverman, G. (2006) Inhibition of autoimmune arthritis by a natural antibody that enhances apoptotic clearance. Arthritis and Rheumatism, 54(9), S355-S355.

Goodyear, C. and Silverman, G. (2006) A microbial toxin forms immune complexes that co-opts cellular Fc gamma R to induce B-cell apoptotic death. Journal of Immunology, 176, S76-S76.

Goodyear, C. , Sugiyama, F. and Silverman, G. (2006) Temporal and dose-dependent relationships between in vivo B cell receptor-targeted proliferation and deletion-induced by a microbial B cell toxin. Journal of Immunology, 176(4), pp. 2262-2271.

Silverman, G. and Goodyear, C. (2006) Confounding B-cell defences: lessons from a staphylococcal superantigen. Nature Reviews Immunology, 6(6), pp. 465-475.

Silverman, G., Goodyear, C. , Germar, K., Kono, D. and Chen, Y. (2006) A therapeutic antibody that enhances apoptotic clearance blocks in vivo TLR-induced cellular activation, and pro-inflammatory cytokine and chemokine production. Arthritis and Rheumatism, 54(9), S450-S450.

Finlay, W., deVore, N., Dobrovolskaia, E., Gam, A., Goodyear, C. and Slater, J. (2005) Exploiting the avian immunoglobulin system to simplify the generation of recombinant antibodies to allergenic proteins. Clinical and Experimental Allergy, 35(8), pp. 1040-1048.

Goodyear, C. , Boyle, D. and Silverman, G. (2005) Secretion of BAFF by fibroblast-like synoviocytes from rheumatoid arthritis biopsies attenuates B-cell depletion by rituximab. Arthritis and Rheumatism, 52(9), S290-S290.

Goodyear, C. and Silverman, G. (2005) B cell superantigens: a microbe's answer to innate-like B cells and natural antibodies. Springer Seminars in Immunopathology, 26(4), pp. 463-484.

Goodyear, C. , Sugiyama, F. and Silverman, G. (2005) Mature splenic B-cell subsets are discordant in their dependence on Birn for in vivo BCR-mediated cell death. FASEB Journal, 19(4), A953-A954.

Silverman, G., Goodyear, C. and Siegel, D. (2005) On the mechanism of staphylococcal protein A immunomodulation. Transfusion, 45(2), pp. 274-280.

Silverman, G., Haraldsson, M., Goodyear, C. , Chen, Y. and Kono, D. (2005) Passive monoclonal antibody treatment that enhances clearance of apoptotic particles improves survival in lupus-prone (NZWxBXSB)F1 mice. Arthritis and Rheumatism, 52(9), S699-S700.

Anderson, J., Mueller, J., Rosengren, S., Boyle, D., Schaner, P., Cannon, S., Goodyear, C. and Hoffman, H. (2004) Structural, expression, and evolutionary analysis of mouse CIASI. Gene, 338(1), pp. 25-34.

Goodyear, C. , Narita, M. and Silverman, G. (2004) In vivo V-L-targeted activation-induced apoptotic supraclonal deletion by a microbial B cell toxin. Journal of Immunology, 172(5), pp. 2870-2877.

Goodyear, C. and Silverman, G. (2004) Staphylococcal toxin induced preferential and prolonged in vivo deletion of innate-like B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America, 101(31), pp. 11392-11397. (doi: 10.1073/pnas.0404382101)

Binder, C., Horkko, S., Dewan, A., Chang, M., Kieu, E., Goodyear, C. , Shaw, P., Palinski, W., Witztum, J. and Silverman, G. (2003) Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nature Medicine, 9(6), pp. 736-743.

Goodyear, C. and Silverman, G. (2003) Characterization of a pro-apoptotic natural Ligand-BCR co-complex. FASEB Journal, 17(7), C261-C261.

Goodyear, C. and Silverman, G. (2003) Death by a B cell superantigen: In vivo V-H-targeted apoptotic supraclonal B cell deletion by a staphylococcal toxin. Journal of Experimental Medicine, 197(9), pp. 1125-1139.

Shaw, P., Goodyear, C. , Chang, M., Witztum, J. and Silverman, G. (2003) The autoreactivity of anti-phosphorylcholine antibodies for atherosclerosis-associated neo-antigens and apoptotic cells. Journal of Immunology, 170(12), pp. 6151-6157.

Finlay, W., Goodyear, C. and Slater, J. (2002) Analysis of IgE heavy chain sequences from a small volume of peripheral blood from a mildly atopic individual. Journal of Allergy and Clinical Immunology, 109(1), S112-S112.

Silverman, G. and Goodyear, C. (2002) A model B-cell superantigen and the immunobiology of B lymphocytes. Clinical Immunology, 102(2), pp. 117-134.

Silverman, G., Jenne, K. and Goodyear, C. (2002) In vivo VH targeted B-cell apoptotic deletion in nice and non-human primates. FASEB Journal, 16(4), A310-A310.

Goodyear, C. and Silverman, G. (2001) Mechanisms of B-cell superantigen-mediated activation-induced cell death. FASEB Journal, 15(4), A694-A694.

O'Hanlon, G.M. et al. (2001) Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal. Brain, 124(5), pp. 893-906. (doi: 10.1093/brain/124.5.893)

Bullens, R.W.M., O'Hanlon, G.M., Goodyear, C.S. , Molenaar, P.C., Conner, J., Willison, H.J. and Plomp, J.J. (2000) Anti-GQ1b antibodies and evoked acetylcholine release at mouse motor endplates. Muscle and Nerve, 23(7), pp. 1035-1043. (doi: 10.1002/1097-4598(200007)23:7<1035::AID-MUS5>3.0.CO;2-R)

Goodyear, C.S. , O'Hanlon, G.M., Plomp, J.J., Wagner, E.R., Cochrane, L., Bullens, R.W.M., Molenaar, P.C., Conner, J. and Willison, H.J. (1999) Monoclonal antibodies raised against Guillain-Barr. Journal of Clinical Investigation, 104(6), pp. 697-708. (doi: 10.1172/JCI6837)

Book Sections

Goodyear, C.S. and Silverman, G.J. (2002) Phage-display approaches for the study of protein-protein interactions. In: Golemis, E. (ed.) Protein-Protein Interactions: A Molecular Cloning Manual. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, NY, USA, pp. 143-166. ISBN 9780879696047

Conference or Workshop Item

Lindsay, S. , Molęda, A., Maclellan, L., Linington, C. , Goodyear, C. and Barnett, S. (2021) Severe experimental autoimmune encephalomyelitis (EAE) is ameliorated by human olfactory-derived mesenchymal stromal cell transplantation revealing a role for IL-16. XV European Meeting on Glial Cells in Health and Disease, 5-9 July 2021. E430-E432. (doi: 10.1002/glia.24036)

Sherrard Smith, R., Lindsay, S.L. , Goodyear, C. , Turnbull, J. and Barnett, S.C. (2021) Heparan Sulphate mimetics as a therapeutic for central nervous system repair. XV European Meeting on Glial Cells in Health and Disease, 5-9 July 2021. E513-E514. (doi: 10.1002/glia.24036)

Lindsay, S.L. , McElroy, D.E., Goodyear, C.S. and Barnett, S.C. (2017) Severe experimental autoimmune encephalomyelitis (EAE) is ameliorated by human olfactory-derived mesenchymal stromal cell transplantation. XIII European Meeting on Glial Cells in Health and Disease, Edinburgh, Scotland, 08-11 Jul 2017. E516. (doi: 10.1002/glia.23157)

Williams, M. T., Thümmler, K., Kitson, S., Soutar, R. and Goodyear, C. S. (2015) 3011 Fc Receptor Targeting Reduces Bone Disease in a Pre-Clinical Model of Multiple Myeloma. 57th ASH Annual Meeting and Exposition, Orange County, FL, USA, 4-8 Dec 2015.

Ansalone, C. , Utriainen, L., Milling, S. W.F. and Goodyear, C. S. (2015) Gut Inflammation in HLA-B27 Transgenic Rats Alters the Monocyte Compartment and Its Osteoclastogenic Potential. ACR/ARHP Annual Meeting, San Francisco, CA, USA, 6-11 Nov 2015.

Ansalone, C. , Milling, S. and Goodyear, C. S. (2015) HLA-B27 Over-Expression in Rats Alters Central and Peripheral Monocyte Populations. 35th European Workshop for Rheumatology Research, Budapest, Hungary, 05-07 Mar 2015. (doi: 10.1136/annrheumdis-2015-207259.31)

This list was generated on Sun Dec 8 06:36:02 2024 GMT.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Uncovering T cells Transition of Psoriatic Arthritis Patients to discover Future Therapeutic Targets
    Tenovus Scotland
    2024 - 2025
     
  • EMINENT - IL-18
    Medical Research Council
    2023 - 2025
     
  • Identification of novel drug targets for large vessel vasculitis
    Vasculitis UK
    2023 - 2025
     
  • EPI-PsA: Unravelling myeloid epigenetic signatures in Psoriasis and Psoriatic Arthritis
    AMGEN (Europe) GmbH
    2023 - 2024
     
  • Characterising The Spatial Transcriptomic Immune Cell Signature of Large Vessel Vasculitis for Drug Target Discovery
    Tenovus Scotland
    2023 - 2024
     
  • OCTAVE DUO - Vaccine Task Force phase1
    Medical Research Council
    2021 - 2022
     
  • HIPPOCRATES
    European Commission
    2021 - 2025
     
  • A first-in-class peptide-based platform delivery technology to modulate mitochondria function in disease
    Medical Research Council
    2021 - 2022
     
  • A first-in-class peptie-based platform delivery technology to modulate mitochondria function in disease
    Medical Research Council
    2021 - 2022
     
  • A first-in-class peptide-based platform delivery technology to modulate mitochondria function in disease
    Medical Research Council
    2021 - 2022
     
  • Developing an Adoptive Regulatory T Cell Therapy for the Treatment of Rheumatoid Arthritis
    Office of the Chief Scientific Adviser
    2021 - 2024
     
  • OPTIMISE
    National Institute for Health Research
    2020 - 2024
     
  • COVID Vaccine response - OCTAVE
    Medical Research Council
    2020 - 2022
     
  • Dissecting innate immune determinants of severity and resolution in a longitudinal study of COVID-19
    UK Research and Innovation
    2020 - 2022
     
  • Rapid New Methods for Sepsis Diagnosis in Hospitals Using Microsystems
    Office of the Chief Scientific Adviser
    2020 - 2023
     
  • Host mitochrondria dysfunction by viral hijacking as a key pathogenicity mechanism in COVID-19
    Wellcome Trust
    2020 - 2021
     
  • Targeting osteoarthritic pain through Proteinase Activated Receptor 2 (PAR2)
    Versus Arthritis
    2020 - 2021
     
  • Delineating disease-relevant T cell subsets in rheumatoid arthritis: potential biomarkers of therapeutic response.
    Chief Scientist Office
    2020 - 2022
     
  • Rapid new methods for sepsis diagnosis in hospitals using microsystems
    Chief Scientist Office
    2020 - 2022
     
  • RACE Renewal
    Versus Arthritis
    2019 - 2024
     
  • ArthritisHeal
    European Commission
    2019 - 2023
     
  • Flexible Talent Mobility Accounts
    Biotechnology and Biological Sciences Research Council
    2017 - 2019
     
  • Rheuma Tolerance for Cure
    European Commission
    2017 - 2022
     
  • BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (BIO-FLARE study)
    Medical Research Council
    2017 - 2021
     
  • CiC Prognostic biomarkers in rheumatoid arthritis
    Medical Research Council
    2017 - 2017
     
  • CiC Translation of nanotechnology for improved bone regeneration
    Medical Research Council
    2016 - 2018
     
  • Are mesenchymal stem cells (MSCs) isolated from the olfactory mucosa a better source of cells for treatment of MS than bone marrow MSCs
    National Multiple Sclerosis Society
    2015 - 2017
     
  • Dissecting the function of Bcl-3 in NF-kappaB signaling in B cells
    Biotechnology and Biological Sciences Research Council
    2015 - 2018
     
  • Consortium of Neuroimmunology of Mood Disorders and Alzheimer's Disease
    Wellcome Trust
    2015 - 2018
     
  • Flow cytometric evaluation of immune signatures in severely malnourished children
    Imperial College London
    2014 - 2016
     
  • Developing USP7 as a therapeutic target in RA
    Arthritis Research UK
    2014 - 2015
     
  • The use of polyomic analyses to direct biologic therapy in biologic-naive people with Rheumatoid Arthritis
    Chief Scientist Office
    2013 - 2015
     
  • Comparing the immunophenotype of common inflammatory diseases to understand their pathogenesis.
    Chief Scientist Office
    2013 - 2016
     
  • Targeting bone disease in myeloma
    Worldwide Cancer Research
    2013 - 2015
     
  • Lessening the burden of osteoarthritis: elucidating the pathogenic role of the PAR-2 Pathway.
    Arthritis Research UK
    2013 - 2018
     
  • OSTEOIMMUNE: Unrevealing the Interactions between the Immune System and Bone
    European Commission
    2012 - 2016
     
  • An Immunological Toolkit for Clinical Application
    Medical Research Council
    2012 - 2017
     
  • The FLEXCELL FX-5000T Tension System; reintroducing cyclical mechanical strain to cell culture systems
    Arthritis Research UK
    2012 - 2013
     
  • Dendritic Cells in Ankylosing Spondylitis
    Arthritis Research UK
    2011 - 2013
     
  • The simultaneous targeting of inflammatory and osteoglastogenic mechanisms in rheumatoid arthritis
    Arthritis Research UK
    2011 - 2013
     
  • Inhibition of osteoclastogenesis by immunomodulatory complexes
    Medical Research Scotland
    2010 - 2013
     
  • Function of the chemokine receptor D6 on innate-like B cells
    Biotechnology and Biological Sciences Research Council
    2009 - 2012
     
  • The effect of B Cell depletion on atherosclerosis
    Tenovus Scotland
    2008 - 2009
     
  • RA-associated factors and their affect on B cell targeted cell death
    Arthritis Research UK
    2006 - 2011
     

Supervision

  • Dobrea, Alexandra
    Point-of-care sensors for monitoring women’s reproductive health

Research datasets

Jump to: 2021
Number of items: 1.

2021

Kennedy, J., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P., Reid, S., Young, P., Meek, D., Goodyear, C. and Dalby, M. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. [Data Collection]

This list was generated on Sun Dec 8 07:26:40 2024 GMT.

Additional information

Invited International Presentations

  • 2016: Hamburg, Germany - Plenary speaker and session chair at Immunobone international meeting
  • 2016: UK - Arthritis UK fellows' meeting
  • 2015: San Francisco, CA, USA - American College of Rheumatology conference
  • 2015: Oxford, UK - Becton Dickenson Advanced flow cytometry meeting
  • 2014: Southampton, England, UK - Wessex Immunology Group Annual meeting
  • 2012: Scotland, UK - University of the West of Scotland IBEHR Research Seminar Series
  • 2012: Ottawa, Ontario, Canada - Bill and Melinda Gates Grand Challenges Meeting
  • 2012: Edinburgh, Scotland, UK - Edinburgh University MRC Centre for Inflammation Research Seminar Series
  • 2012: Crete, Greece - 17th World Congress on Advances in Oncology and 15th International Symposium on Molecular Medicine
  • 2011: London, England, UK - Imperial College Division of Immunology and Inflammation Seminar Series
  • 2011: Glasgow, Scotland, UK - European School of Neuroimmunology
  • 2011: Singapore - Anti-lipid antibody workshop, National University of Singapore
  • 2011: UK - Nuffield Foundation Oliver Bird Rheumatology PhD Programme annual meeting
  • 2011: Scotland, UK - West of Scotland Cancer Network, Haemato-oncology MCN Education Day
  • 2010: Norway - Keynote at The Norwegian Cardiovascular and Rheumatology Conference
  • 2009: Philadelphia, Pennsylvania, USA - American College of Rheumatology conference
  • 2009: Glasgow, Scotland, UK - British Society for Rheumatology conference
  • 2009: Edinburgh, Scotland, UK - Royal College of Physicians of Edinburgh Rheumatology Symposium
  • 2009: Southampton, England, UK - University of Southampton School of Medicine Cancer sciences seminar series
  • 2008: London, England, UK - Windeyer External Speaker Programme at the Division of Infection and Immunity at UCL
  • 2006: Buzios, Rio de Janerio, Brazil - XXXI Congress of the Brazilian Society for Immunology - "Signaling in the Immune System"
  • 2004: Cold Spring Harbor Laboratories, New York, USA - Course on Phage Display on Combinatorial Antibody Libraries - The Biology of B Cells

Prizes, Awards and Distinctions

  • 2015: Royal Society of Biology - Fellow
  • 2014: University of Newcastle - Visiting research fellow
  • 2014: University of Birmingham - Visiting research fellow
  • 2010: Medical Research Scotland - Inaugural Medical Research Scotland Vipiana Award
  • 2010: University of West of Scotland - Visiting research fellow
  • 2006: American Association of Immunologists - Junior Faculty Award
  • 2005: Arthritis Foundation - Investigator Award
  • 2005: National Blood Foundation - David B. Pall Prize for Innovative Research in Transfusion Medicine
  • 2004: National Blood Foundation - Scholar

Professional Learned Society

  • 2006 - present: British Society for Immunology - Member
  • 2004 - present: American Association of Immunology - Member
  • 2004 - 2006: NCI designated UCSD Cancer Center - Member
  • 2004 - 2006: NIAMS designated UCSD Rheumatic Diseases Core Center - Member

Research Fellowship

  • 2011 - 2013: Arthritis Research UK Progression Fellowship
  • 2007 - 2012: Arthritis Research Campaign - Non-Clinical Career Development Fellow
  • 2000 - 2003: Cancer Research Institute - Postdoctoral Fellow