Prof Iain Mcinnes

  • Muirhead Chair of Medicine & Director of Institute (Immunology)

telephone: 01413308412
email: Iain.McInnes@glasgow.ac.uk

B4/17
III - GBRC
University Place
Glasgow G12 8TA


Professor McInnes has a major interest in the biology of inflammatory synovitis in rheumatoid arthritis, psoriatic arthritis and septic arthritis. He operates a translational science programme in which state of the art cellular and molecular biology techniques area applied to elucidate the mechanisms underlying the perpetuation of synovial inflammation. In parallel they have an extensive clinical trials facility in which they perform studies of novel biologic agents in inflammatory arthritis.

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Number of items: 207.

2014

Nurmohamed, Michael T, Jamnitski, Anna, Symmons, Deborah, Peters, Mike Johannes Leonardus, Sattar, Naveed, and McInnes, Iain (2014) Response to: 'The influence of inflammation in the development of subclinical atherosclerosis in psoriatic arthritis' by Gonzalez-Gay et al. Annals of the Rheumatic Diseases, 73 (5). e28. ISSN 0003-4967 (doi:10.1136/annrheumdis-2014-205174)

Rice, Gillian I et al. (2014) Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling. Nature Genetics, 46 (5). pp. 503-509. ISSN 1061-4036 (doi:10.1038/ng.2933)

Patterson, H., Nibbs, R., McInnes, I., and Siebert, S. (2014) Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases. Clinical and Experimental Immunology, 176 (1). pp. 1-10. ISSN 0009-9104 (doi:10.1111/cei.12248)

Dale, J., Purves, D., McConnachie, A., McInnes, I., and Porter, D. (2014) Tightening up? Impact of musculoskeletal ultrasound disease activity assessment on early rheumatoid arthritis patients treated using a treat to target strategy. Arthritis Care and Research, 66 (1). pp. 19-26. ISSN 2151-464X (doi:10.1002/acr.22218)

Dougados, M. et al. (2014) Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA). Annals of the Rheumatic Diseases, 73 (1). pp. 62-68. ISSN 0003-4967 (doi:10.1136/annrheumdis-2013-204223)

Frleta, Marina, Siebert, Stefan, and McInnes, Iain B. (2014) The interleukin-17 pathway in psoriasis and psoriatic arthritis: disease pathogenesis and possibilities of treatment. Current Rheumatology Reports, 16 (414). ISSN 1523-3774 (doi:10.1007/s11926-014-0414-y)

McInnes, I.B. et al. (2014) Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Annals of the Rheumatic Diseases, 73 (2). pp. 349-356. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-202646)

Paul, L., Rafferty, D., Marshall-Mckenna, R., Gill, J.M.R., McInnes, I., Porter, D., and Woodburn, J. (2014) Oxygen cost of walking, physical activity, and sedentary behaviours in rheumatoid arthritis. Scandinavian Journal of Rheumatology, 43 (1). pp. 28-34. ISSN 0300-9742 (doi:10.3109/03009742.2013.802009)

Turner, Deborah E., Hyslop, Elaine, Barn, Ruth, McInnes, Iain B., Steultjens, Martijn P.M., and Woodburn, James (2014) Metatarsophalangeal joint pain in psoriatic arthritis: a cross-sectional study. Rheumatology, 53 (4). pp. 737-740. ISSN 1462-0324 (doi:10.1093/rheumatology/ket435)

2013

Lappin, D.F., Apatzidou, D., Quirke, A.M., Oliver-Bell, J., Butcher, J.P., Kinane, D.F., Riggio, M.P., Venables, P., McInnes, I.B., and Culshaw, S. (2013) Influence of periodontal disease, porphyromonas gingivalisand cigarette smoking on systemic anti-citrullinated peptide antibody titres. Journal of Clinical Periodontology, 40 (10). pp. 907-915. ISSN 0303-6979 (doi:10.1111/jcpe.12138)

van den Berg, W.B., and McInnes, I.B. (2013) Th17 cells and IL-17 A—Focus on immunopathogenesis and immunotherapeutics. Seminars in Arthritis and Rheumatism, 43 (2). pp. 158-170. ISSN 0049-0172 (doi:10.1016/j.semarthrit.2013.04.006)

Robertson, J., Peters, M.J., McInnes, I.B., and Sattar, N. (2013) Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm. Nature Reviews Rheumatology, 9 (9). pp. 513-523. ISSN 1759-4790 (doi:10.1038/nrrheum.2013.91)

Miller, A.M., Gilchrist, D.S., Nijjar, J., Araldi, E., Ramirez, C.M., Lavery, C.A., Fernandez-Hernando, C., McInnes, I., and Kurowska-Stolarska, M. (2013) MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis. PLoS ONE, 8 (8). e72324. ISSN 1932-6203 (doi:10.1371/journal.pone.007232)

McInnes, I.B. et al. (2013) Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial. Lancet, 382 (9894). pp. 780-789. ISSN 1474-547X (doi:10.1016/S0140-6736(13)60594-2)

Schett, G., Elewaut, D., McInnes, I.B., Dayer, J.-M., and Neurath, M.F. (2013) How cytokine networks fuel inflammation: toward a cytokine-based disease taxonomy. Nature Medicine, 19 (7). pp. 822-824. ISSN 1078-8956 (doi:10.1038/nm.3260)

Weir, Robin A.P. et al. (2013) Response to letter regarding article, "Galectin-3 and cardiac function in survivors of acute myocardial infarction". Circulation: Heart Failure, 6 (4). e58. ISSN 1941-3289 (doi:10.1161/CIRCHEARTFAILURE.113.000382)

Kapoor, S.R., Filer, A., Fitzpatrick, M.A., Fisher, B.A., Taylor, P.C., Buckley, C.D., McInnes, I.B., Raza, K., and Young, S.P. (2013) Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis. Arthritis and Rheumatism, 65 (6). pp. 1448-1456. ISSN 0004-3591 (doi:10.1002/art.37921)

Weir, Robin A.P. et al. (2013) Galectin-3 and cardiac function in survivors of acute myocardial infarction. Circulation: Heart Failure, 6 (3). pp. 492-498. ISSN 1941-3289 (doi:10.1161/CIRCHEARTFAILURE.112.000146)

Villeneuve, E. et al. (2013) Republished: a systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Postgraduate Medical Journal, 89 (1050). pp. 231-240. ISSN 0032-5473 (doi:10.1136/postgradmedj-2011-201063rep)

van der Heijde, D. et al. (2013) EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria. Annals of the Rheumatic Diseases, 72 (4). pp. 479-481. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-202779)

O'Shea, J.J., Laurence, A., and McInnes, I.B. (2013) Back to the future: oral targeted therapy for RA and other autoimmune diseases. Nature Reviews Rheumatology, 9 (3). pp. 173-182. ISSN 1759-4790 (doi:10.1038/nrrheum.2013.7)

Villeneuve, E. et al. (2013) A systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Annals of the Rheumatic Diseases, 72 (1). pp. 13-22. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-201063)

Wagner, C.L. et al. (2013) Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab. Annals of the Rheumatic Diseases, 72 (1). pp. 83-88. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-201697)

Asquith, D.L. et al. (2013) The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release. Annals of the Rheumatic Diseases, 72 (12). pp. 2024-2031. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-202872)

Coates, L.C. et al. (2013) The 2012 BSR and BHPR guideline for the treatment of psoriatic arthritis with biologics. Rheumatology, 52 (10). pp. 1754-1757. ISSN 1462-0324 (doi:10.1093/rheumatology/ket187)

Crilly, A., Palmer, H.S., Nickdel, M.B., Dunning, L., Lockhart, J.C., Plevin, R., McInnes, I.B., and Ferrell, W.R. (2013) Immunomodulatory role of proteinase-activated receptor-2. Annals of the Rheumatic Diseases, 71 (9). pp. 1559-1566. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200869)

Jamnitski, A., Symmons, D., Peters, M.J.L., Sattar, N., McInnes, I., and Nurmohamed, M.T. (2013) Cardiovascular comorbidities in patients with psoriatic arthritis: a systematic review. Annals of the Rheumatic Diseases, 72 (2). pp. 211-216. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-201194)

Kavanaugh, A. et al. (2013) Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study. Annals of the Rheumatic Diseases, 72 (11). pp. 1777-1785. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-202035)

McInnes, I.B., Combe, B., and Burmester, G. (2013) Understanding the patient perspective: results of the rheumatoid arthritis: insights, strategies and expectations (RAISE) patient needs survey. Clinical and Experimental Rheumatology, 31 (3). pp. 350-7. ISSN 0392-856X

Millar, N., Murrell, G.A.C., and McInnes, I. (2013) Alarmins in tendinopathy: unravelling new mechanisms in a common disease. Rheumatology, 52 (5). pp. 769-779. ISSN 1462-0324

Miller, Ashley M., Gilchrist, Derek S., Nijjar, Jagtar, Araldi, Elisa, Ramirez, Cristina M., Lavery, Christopher A., Fernández-Hernando, Carlos, McInnes, Iain B., and Kurowska-Stolarska, Mariola (2013) MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice. PLoS ONE, 8 (8). e72324. ISSN 1932-6203 (doi:10.1371/journal.pone.0072324)

Nijjar, J., Tindell, A., McInnes, I.B., and Siebert, S. (2013) Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis. Rheumatology, 52 (9). pp. 1556-1562. ISSN 1462-0324 (doi:10.1093/rheumatology/ket225)

Steven, Rachael, Crilly, Anne, Lockhart, John C., Ferrell, William R., and McInnes, Iain B. (2013) Proteinase-activated receptor-2 modulates human macrophage differentiation andeffector function. Innate Immunity, 19 (6). pp. 663-672. ISSN 1753-4259 (doi:10.1177/1753425913479984)

2012

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32 (11). pp. 2569-2579. ISSN 1079-5642 (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7 (11). e49715. ISSN 1932-6203 (doi:10.1371/journal.pone.0049715)

Miller, Ashley M. et al. (2012) Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? PLoS ONE, 7 (10). e47830. ISSN 1932-6203 (doi:10.1371/journal.pone.0047830)

Haneklaus, M., Gerlic, M., Kurowska-Stolarska, M., Rainey, A.-A., Pich, D., McInnes, I.B., Hammerschmidt, W., O'Neill, L.A.J., and Masters, S.L. (2012) Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1 production. Journal of Immunology, 189 (8). pp. 3795-3799. ISSN 0022-1767 (doi:10.4049/jimmunol.1200312)

Keystone, E. C., Wang, M. M., Layton, M., Hollis, S., and McInnes, I.B. (2012) Clinical evaluation of the efficacy of the P2X7 purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine. Annals of the Rheumatic Diseases, 71 (10). pp. 1630-1635. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-143578)

Utriainen, Lotta, Firmin, Dawn, Wright, Pamela, Cerovic, Vuk, Breban, Maxime, McInnes, Iain, and Milling, Simon (2012) Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis. Arthritis and Rheumatism, 64 (10). pp. 3199-3209. ISSN 0004-3591 (doi:10.1002/art.34561)

Weir, Robin A.P., Miller, Ashley M., Petrie, Colin J., Clements, Suzanne, Steedman, Tracey, Dargie, Henry J., Squire, Iain B., Ng, Leong L., McInnes, Iain B., and McMurray, John J.V. (2012) Interleukin-21 – a biomarker of importance in predicting myocardial function following acute infarction? Cytokine, 60 (1). pp. 220-225. ISSN 1043-4666 (doi:10.1016/j.cyto.2012.06.002)

Singh, M.D. et al. (2012) Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis. American Journal of Pathology, 181 (4). pp. 1158-1164. ISSN 0002-9440 (doi:10.1016/j.ajpath.2012.06.042)

Tindell, A.G., Kelso, E.B., Ferrell, W.R., Lockhart, J.C., Walsh, D.A., Dunning, L., and McInnes, I.B. (2012) Correlation of protease-activated receptor-2 expression and synovitis in rheumatoid and osteoarthritis. Rheumatology International, 32 (10). pp. 3077-3086. ISSN 0172-8172 (doi:10.1007/s00296-011-2102-9)

Komai-Koma, M. et al. (2012) Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice. Allergy, 67 (9). pp. 1118-1126. ISSN 0105-4538 (doi:10.1111/j.1398-9995.2012.02859.x)

Kavanaugh, A. et al. (2012) Golimumab in psoriatic arthritis: one-year clinical efficacy, radiographic, and safety results from a phase III, randomized, placebo-controlled trial. Arthritis and Rheumatism, 64 (8). pp. 2504-2517. ISSN 0004-3591 (doi:10.1002/art.34436)

Crilly, A. et al. (2012) PAR2 expression in peripheral blood monocytes of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71 (6). pp. 1049-1054. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200703)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119 (11). pp. 2545-2551. ISSN 0006-4971 (doi:10.1182/blood-2011-09-378356)

Baxter, D., McInnes, I.B., and Kurowska-Stolarska, M. (2012) Novel regulatory mechanisms in inflammatory arthritis: a role for microRNA. Immunology and Cell Biology, 90 (3). pp. 288-292. ISSN 0818-9641 (doi:10.1038/icb.2011.114)

Frleta, M., King, V., Reilly, J.H., Gilchrist, D.S., Tornehave, D., Lundsgaard, D., Miller, A.M., and McInnes, I.B. (2012) Expression of IL-21 receptor in synovial tissue and blood of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71 (Sup. 1). A83. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-201238.25)

Gossec, L. et al. (2012) European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Annals of the Rheumatic Diseases, 71 (1). pp. 4-12. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200350)

Henningsson, L., Jirholt, P., Bogestal, Y.R., Eneljung, T., Adiels, M., Lindholm, C., McInnes, I., Bulfone-Paus, S., Lerner, U.H., and Gjertsson, I. (2012) Interleukin 15 mediates joint destruction in Staphylococcus aureus arthritis. Journal of Infectious Diseases, 206 (5). pp. 687-696. ISSN 0022-1899 (doi:10.1093/infdis/jis295)

Johnsson, H., McInnes, I.B., and Sattar, N. (2012) Cardiovascular and metabolic risks in psoriasis and psoriatic arthritis: pragmatic clinical management based on available evidence. Annals of the Rheumatic Diseases, 71 (4). pp. 480-483. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200567)

Kerekes, G., Soltész, P., Nurmohamed, M.T., Gonzalez-Gay, M.A., Turiel, M., Végh, E., Shoenfeld, Y., McInnes, I., and Szekanecz, Z. (2012) Validated methods for assessment of subclinical atherosclerosis in rheumatology. Nature Reviews Rheumatology, 8 (4). pp. 224-234. ISSN 1759-4790 (doi:10.1038/nrrheum.2012.16)

Lories, R.J., and McInnes, I.B. (2012) Primed for inflammation: enthesis-resident T cells. Nature Medicine, 18 (7). pp. 1018-1019. ISSN 1078-8956 (doi:10.1038/nm.2854)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84 (14). pp. 5968-5975. ISSN 0003-2700 (doi:10.1021/ac3006445)

Millar, N.L., Reilly, J.H., Kerr, S.C., Campbell, A.L., Little, K.J., Leach, W.J., Rooney, B.P., Murrell, G.A.C., and McInnes, I.B. (2012) Hypoxia: a critical regulator of early human tendinopathy. Annals of the Rheumatic Diseases, 71 (2). pp. 302-310. ISSN 0003-4967 (doi:10.1136/ard.2011.154229)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7 (11). e49715. ISSN 1932-6203 (doi:10.1371/journal.pone.0049715)

Steinman, L., Merrill, J.T., McInnes, I.B., and Peakman, M. (2012) Optimization of current and future therapy for autoimmune diseases. Nature Medicine, 18 (1). pp. 59-65. ISSN 1078-8956 (doi:10.1038/nm.2625)

Wenink, M.H., Santegoets, K.C.M., Platt, A.M., van den Berg, W.B., van Riel, P.L.C.M., Garside, P., Radstake, T.R.D.J., and McInnes, I.B. (2012) Abatacept modulates proinflammatory macrophage responses upon cytokine-activated T cell and Toll-like receptor ligand stimulation. Annals of the Rheumatic Diseases, 71 (1). pp. 80-83. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200348)

Xuzhu, G., Komai-Koma, M., Leung, B.P., Howe, H.S., McSharry, C., McInnes, I.B., and Xu, D. (2012) Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. Annals of the Rheumatic Diseases, 71 (1). pp. 129-135. ISSN 0003-4967 (doi:10.1136/ard.2011.149831)

2011

McInnes, I.B., and Schett, G. (2011) The pathogenesis of rheumatoid arthritis. New England Journal of Medicine, 365 (23). pp. 2205-2219. ISSN 0028-4793 (doi:10.1056/NEJMra1004965)

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! FEBS Letters, 585 (23). pp. 2640-3648. ISSN 0014-5793 (doi:10.1016/j.febslet.2011.04.069)

Wenink, M.H., Santegoets, K.C.M., Butcher, J., van Bon, L., Lamers-Karnebeek, F.G.M., van den Berg, W.B., van Riel, P.L.C.M., McInnes, I.B., and Radstake, T.R.D.J. (2011) Impaired dendritic cell proinflammatory cytokine production in psoriatic arthritis. Arthritis and Rheumatism, 63 (11). pp. 3313-3322. ISSN 0004-3591 (doi:10.1002/art.30577)

Welsh, Paul et al. (2011) Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arteriosclerosis, Thrombosis and Vascular Biology, 31 (10). pp. 2338-2344. ISSN 1079-5642 (doi:10.1161/ATVBAHA.111.231795)

Hueber, Axel J., Alves-Filho, Jose C., Asquith, Darren L., Michels, Chesney , Millar, Neal L., Reilly, James H., Graham, Gerry J., Liew, Foo Y., Miller, Ashley M., and McInnes, Iain B. (2011) IL-33 induces skin inflammation with mast cell and neutrophil activation. European Journal of Immunology, 41 (8). pp. 2229-2237. ISSN 0014-2980 (doi:10.1002/eji.201041360)

Conigliaro, P., Benson, R.A., Patakas, A., Kelly, S.M., Valesini, G., Homdahl, R., Brewer, J.M., McInnes, I.B., and Garside, P. (2011) Characterization of the anti-collagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63 (8). pp. 2299-2308. ISSN 0004-3591 (doi:10.1002/art.30413)

Conigliaro, Paola, Benson, Robert A., Patakas, Agapitos, Kelly, Sharon M., Valesini, Guido, Holmdahl, Rikard, Brewer, James M., McInnes, Iain B., and Garside, Paul (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63 (8). pp. 2299-2308. ISSN 0004-3591 (doi:10.1002/art.30413)

Kurowska-Stolarska, Mariola et al. (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proceedings of the National Academy of Sciences of the United States of America, 108 (27). pp. 11193-11198. ISSN 0027-8424 (doi:10.1073/pnas.1019536108)

Patakas, Agapitos, Platt, Andrew M., Butcher, John P., Maffia, Pasquale, McInnes, Iain B., Brewer, James M., Garside, Paul, and Benson, Robert A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138 (1). pp. 38-46. ISSN 0165-2478 (doi:10.1016/j.imlet.2011.03.002)

Zaiss, Mario M. et al. (2011) IL-33 Shifts the Balance from Osteoclast to Alternatively Activated Macrophage Differentiation and Protects from TNF-α–Mediated Bone Loss. Journal of Immunology, 186 (11). pp. 6097-6105. ISSN 0022-1767 (doi:10.4049/jimmunol.1003487)

Welsh, P. et al. (2011) Vitamin D deficiency is common in patients with RA and linked to disease activity, but circulating levels are unaffected by TNF blockade: results from a prospective cohort study. Annals of the Rheumatic Diseases, 70 (6). pp. 1165-1167. ISSN 0003-4967 (doi:10.1136/ard.2010.137265)

Hansell, Chris A. H., Schiering, Chris, Kinstrie, Ross, Ford, Laura, Bordon, Yvonne, McInnes, Iain B., Goodyear, Carl S., and Nibbs, Robert J.B. (2011) Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice. Blood, 117 (20). pp. 5413-5424. ISSN 0006-4971 (doi:10.1182/blood-2010-11-317115)

Krishnadas, R., Mallon, V., McInnes, I., and Cavanagh, J. (2011) Correlates of depression and quality of life in patients with inflammatory arthritides. European Psychiatry, 26 . p. 383. ISSN 0924-9338 (doi:10.1016/S0924-9338(11)72091-0)

Norman, J.E., Yuan, M., Anderson, L., Howie, F., Harold, G., Young, A., Jordan, F., McInnes, I., and Harnett, M.M. (2011) Effect of prolonged in vivo administration of progesterone in pregnancy on myometrial gene expression, peripheral blood leukocyte activation, and circulating steroid hormone levels. Reproductive Sciences, 18 (5). pp. 435-446. ISSN 1933-7191 (doi:10.1177/1933719110395404)

Culshaw, Shauna, McInnes, Iain B., and Liew, Foo Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38 (S11). pp. 106-113. ISSN 0303-6979 (doi:10.1111/j.1600-051X.2010.01669.x)

Codullo, Veronica et al. (2011) An investigation of the inflammatory cytokine and chemokine network in systemic sclerosis. Annals of the Rheumatic Diseases, 70 (6). pp. 1115-1121. ISSN 0003-4967 (doi:10.1136/ard.2010.137349 )

Miller, A., and McInnes, Iain (2011) Cytokines as therapeutic targets to reduce cardiovascular risk in chronic inflammation. Current Pharmaceutical Design, 17 (1). pp. 1-8. ISSN 1381-6128 (doi:10.2174/138161211795049796)

Asquith, D.L., Miller, A.M., Reilly, J.H., Kerr, S., Welsh, P., Sattar, N., and McInnes, I.B. (2011) Simultaneous activation of the liver X receptors (LXR and LXR) drives murine collagen-induced arthritis disease pathology. Annals of the Rheumatic Diseases, 70 (12). pp. 2225-2228. ISSN 0003-4967 (doi:10.1136/ard.2011.152652)

Bombardieri, M., Kam, N.-W., Brentano, F., Choi, K., Filer, A., Kyburz, D., McInnes, I.B., Gay, S., Buckley, C., and Pitzalis, C. (2011) A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells. Annals of the Rheumatic Diseases, 70 (10). pp. 1857-1865. ISSN 0003-4967 (doi:10.1136/ard.2011.150219)

Crilly, A., Robertson, S.E., Reilly, J.H., Gracie, J.A., Lai, W.-Q., Leung, B.P., Life, P.F., and McInnes, I.B. (2011) Phosphodiesterase 4 (PDE4) regulation of proinflammatory cytokine and chemokine release from rheumatoid synovial membrane. Annals of the Rheumatic Diseases, 70 (6). pp. 1130-1137. ISSN 0003-4967 (doi:10.1136/ard.2010.134825)

Laing, S., Hernandez-Santana, A., Sassmannshausen, J., Asquith, D.L., McInnes, I.B., Faulds, K., and Graham, D. (2011) Quantitative Detection of Human Tumor Necrosis Factor α by a Resonance Raman Enzyme-Linked Immunosorbent Assay. Analytical Chemistry, 83 (1). pp. 297-302. ISSN 0003-2700 (doi:10.1021/ac1024039)

MacLellan, L.M., Montgomery, J., Sugiyama, F., Kitson, S.M., Thümmler, K., Silverman, G.J., Beers, S.A., Nibbs, R.J.B., McInnes, I.B., and Goodyear, C.S. (2011) Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice. Arthritis and Rheumatism, 63 (12). pp. 3897-3907. ISSN 0004-3591 (doi:10.1002/art.30629)

Pitman, N., Asquith, D.L., Murphy, G., Liew, F.Y., and McInnes, I.B. (2011) Collagen-induced arthritis is not impaired in mast cell-deficient mice. Annals of the Rheumatic Diseases, 70 (6). pp. 1170-1171. ISSN 0003-4967 (doi:10.1136/ard.2010.134528)

Zwerina, K. et al. (2011) Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance. European Journal of Immunology, 42 (2). pp. 413-423. ISSN 0014-2980 (doi:10.1002/eji.201141871)

van de Sande, M. G. H. et al. (2011) Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials. Annals of the Rheumatic Diseases, 70 (3). pp. 423-427. ISSN 0003-4967 (doi:10.1136/ard.2010.139550)

2010

Miller, Ashley M., Asquith, Darren L., Hueber, Axel J., Anderson, Lesley A., Holmes, William M., McKenzie, Andrew N., Xu, Damo, Sattar, Naveed, McInnes, Iain B., and Liew, Foo Y. (2010) Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circulation Research, 107 (5). pp. 650-658. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.110.218867)

Verri, Waldiceu A. et al. (2010) IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Annals of the Rheumatic Diseases, 69 (9). pp. 1697-1703. ISSN 0003-4967 (doi:10.1136/ard.2009.122655)

Emery, P., Buch, M.H., Östör, A., Kirkham, B., Taylor, P., Estrach, C., Jenkinson, T., McInnes, I., and Porter, D. (2010) Time for treatment targets in rheumatoid arthritis. British Medical Journal, 341 (c4170). p. 267. ISSN 0959-535X (doi:10.1136/bmj.c4170)

Platt, Andrew M., Gibson, Vivienne B., Patakas, Agapitos, Benson, Robert A., Nadler, Steven G., Brewer, James M., McInnes, Iain, and Garside, Paul (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185 (3). pp. 1558-1567. ISSN 0022-1767 (doi:10.4049/jimmunol.1001311 )

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184 (11). pp. 6378-6385. ISSN 0022-1767 (doi:10.4049/jimmunol.0903951)

Hueber, Axel J., Asquith, Darren L., Miller, Ashley M., Reilly, Jim, Kerr, Shauna, Leipe, Jan, Melendez Romero, Alirio J., and McInnes, Iain B. (2010) Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium. Journal of Immunology, 184 (7). pp. 3336-3340. ISSN 0022-1767 (doi:10.4049/jimmunol.0903566)

Xu, Damo et al. (2010) IL-33 exacerbates autoantibody-induced arthritis. Journal of Immunology, 184 (5). pp. 2620-2626. ISSN 0022-1767 (doi:10.4049/jimmunol.0902685)

Asquith, Darren L., Miller, Ashley M., Hueber, Axel J., Liew, Foo Y., Sattar, Naveed, and McInnes, Iain B. (2010) Apolipoprotein E-deficient mice are resistant to the development of collagen-induced arthritis. Arthritis and Rheumatism, 62 (2). pp. 472-477. ISSN 0004-3591 (doi:10.1002/art.27205)

Liew, Foo Y., Pitman, Nick I., and McInnes, Iain B. (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nature Reviews Immunology, 10 (2). pp. 103-110. ISSN 1474-1733 (doi:10.1038/nri2692)

Weir, R.A.P., Miller, A.M., Murphy, G., Clements, S., Steedman, T., Connell, J., McInnes, I., Dargie, H., and McMurray, J.J. (2010) Serum soluble ST2 a potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction. Journal of the American College of Cardiology, 55 (3). pp. 243-250. ISSN 0735-1097 (doi:10.1016/j.jacc.2009.08.047)

Murphy, G.E.J., Xu, D., Liew, F.Y., and McInnes, I.B. (2010) Role of interleukin 33 in human immunopathology. Annals of the Rheumatic Diseases, 69 (Suppl ). pp. 43-47. ISSN 0003-4967 (doi:10.1136/ard.2009.120113)

Cavanagh, J., Paterson, C., McLean, J., Pimlott, S., McDonald, M., Patterson, J., Wyper, D., and McInnes, Iain (2010) Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study. Annals of the Rheumatic Diseases, 69 (6). 1251-U367. ISSN 0003-4967 (doi:10.1136/ard.2009.107912)

Ferrell, W.R., Kelso, E.B., Lockhart, J.C., Plevin, R., and McInnes, I.B. (2010) Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis. Annals of the Rheumatic Diseases, 69 (11). pp. 2051-2054. ISSN 0003-4967 (doi:10.1136/ard.2010.130336)

Fraser, A.R., Perry, M.E., Crilly, A., Reilly, J.H., Hueber, A.J., and McInnes, I.B. (2010) Lipoma arborescens co-existing with psoriatic arthritis releases tumour necrosis factor alpha and matrix metalloproteinase. Annals of the Rheumatic Diseases, 69 (4). pp. 776-777. ISSN 0003-4967 (doi:10.1136/ard.2008.106047)

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, 07-08 June 2010, Manchester, UK.

Hueber, A.J., Asquith, D.L., McInnes, I.B., and Miller, A.M. (2010) Embracing novel cytokines in RA – complexity grows as does opportunity! Best Practice and Research: Clinical Rheumatology, 24 (4). pp. 479-487. ISSN 1521-6942 (doi:10.1016/j.berh.2010.01.004)

Hyslop, E., McInnes, I. B., Woodburn, J., and Turner, D. E. (2010) Foot problems in psoriatic arthritis: high burden and low care provision. Annals of the Rheumatic Diseases, 69 (5). p. 928. ISSN 0003-4967 (doi:10.1136/ard.2009.111971)

Hyslop, E., Woodburn, J., McInnes, I.B., Semple, R., Newcombe, L., Hendry, G., Rafferty, D., De Mits, S., and Turner, D.E. (2010) A reliability study of biomechanical foot function in psoriatic arthritis based on a novel multi-segmented foot model. Gait and Posture, 32 (4). pp. 619-626. ISSN 0966-6362 (doi:10.1016/j.gaitpost.2010.09.004)

Kurowska-Stolarska, M., Hueber, A., Stolarski, B., and McInnes, I. B. (2010) Interleukin-33: a novel mediator with a role in distinct disease pathologies. Journal of Internal Medicine, 269 (1). pp. 29-35. ISSN 0954-6820 (doi:10.1111/j.1365-2796.2010.02316.x)

McInnes, I. B., and O'Dell, J. R. (2010) State-of-the-art: rheumatoid arthritis. Annals of the Rheumatic Diseases, 69 (11). pp. 1898-1906. ISSN 0003-4967 (doi:10.1136/ard.2010.134684)

Millar, N.L., Hueber, A.J., Reilly, J.H., Xu, Y., Fazzi, U.G., Murrell, G.A.C., and McInnes, I.B. (2010) Inflammation is present in early human tendinopathy. American Journal of Sports Medicine, 38 (10). pp. 2085-2091. ISSN 0363-5465 (doi:10.1177/0363546510372613)

2009

Kurowska-Stolarska, Mariola et al. (2009) IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation. Journal of Immunology, 183 (10). pp. 6469-6477. ISSN 0022-1767 (doi:10.4049/jimmunol.0901575)

Lai, Wen-Qi, Irwan, Anastasia Windy, Goh, Hong Heng, Melendez, Alirio J., McInnes, Iain B., and Leung, Bernard P. (2009) Distinct Roles of Sphingosine Kinase 1 and 2 in Murine Collagen-Induced Arthritis. Journal of Immunology, 183 (3). pp. 2097-2103. ISSN 0022-1767 (doi:10.4049/jimmunol.0804376)

Asquith, Darren L., Miller, Ashley M., McInnes, Iain B. , and Liew, Foo Y. (2009) Animal models of rheumatoid arthritis. European Journal of Immunology, 39 (8). pp. 2040-2044. ISSN 0014-2980 (doi:10.1002/eji.200939578 )

McKimmie, Clive S. et al. (2009) A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration. Blood, 113 (18). pp. 4224-4231. ISSN 0006-4971 (doi:10.1182/blood-2008-08-174698 )

Lemos, Henrique P. et al. (2009) Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ  production. Proceedings of the National Academy of Sciences of the United States of America, 106 (14). pp. 5954-5959. ISSN 0027-8424 (doi:10.1073/pnas.0812782106)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182 (2). pp. 963-968. ISSN 0022-1767

Asquith, D, Miller, AM, Hueber, AJ, McKinnon, HJ, Sattar, NA, Graham, GJ, and McInnes, Iain (2009) Liver X Receptor Agonism Promotes Articular Inflammation in Murine Collagen-Induced Arthritis. Arthritis and Rheumatism, 60 (9). pp. 2655-2665. ISSN 0004-3591 (doi:10.1002/art.24717 )

Asquith, D.L., Miller, A.L., McInnes, I.B., and Liew, F.Y. (2009) Autoimmune disease: rheumatoid arthritis. Animal models of rheumatoid arthritis. European Journal of Immunology, 39 . pp. 1991-2058. ISSN 0014-2980

Conigliaro, P, Priori, R, Bombardieri, M, Alessandri, C, Barone, F, Pitzalis, C, McInnes, I, and Valesini, G (2009) Lymph node IL-18 expression in adult-onset Still's disease. Annals of the Rheumatic Diseases, 68 (3). pp. 442-443. ISSN 0003-4967

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, 02-04 Apr 2009, Oxford, Uk.

Dever, G., Rodolico , G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, 29 Apr - 1 May 2009, Washington DC, USA.

Gabay, C, and McInnes, I (2009) The biological and clinical importance of the 'new generation' cytokines in rheumatic diseases. Arthritis Research and Therapy, 11 (3).

Hueber, AJ, and McInnes, I (2009) Is spleen tyrosine kinase inhibition an effective therapy for patients with RA? Nature Clinical Practice Rheumatology, 5 (3). pp. 130-131.

Hueber, AJ, Stevenson, RD, Stokes, RJ, Graham, D, Garside, P, and McInnes, I (2009) Imaging inflammation in real time-future of nanoparticles. Autoimmunity, 42 (4). pp. 368-372.

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155 (1). pp. 107-116. ISSN 0009-9104

McInnes, I (2009) Does practice mirror the evidence base in the treatment of rheumatoid arthritis? Clinical Rheumatology, 28 (8). pp. 961-970.

McKellar, GE, McCarey, DW, Sattar, NA, and McInnes, I (2009) Role for TNF in atherosclerosis? Lessons from autoimmune disease. Nature Reviews Cardiology, 6 (6). pp. 410-417.

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68 (6). pp. 1059-1066. ISSN 0003-4967 (doi:10.1136/ard.2008.089300)

Patel, M, McInnes, I, and Graham, G (2009) Atypical Chemokine Receptors in Inflammatory Disease. Current Molecular Medicine, 9 (1). pp. 86-93. ISSN 1566-5240

Yuan, M, Jordan, F, McInnes, I, Harnett, M, and Norman, JE (2009) Leukocytes are primed in peripheral blood for activation during term and preterm labour. Molecular Human Reproduction, 15 (11). pp. 713-724. ISSN 1360-9947 (doi:10.1093/molehr/gap054)

2008

Lai, Wen-Qi, Irwan, Anastasia Windy, Goh, Hong Heng, Howe, Hwee Siew, Yu, David T., Valle-Onate, Rafael, McInnes, Iain B., Melendez, Alirio J., and Leung, Bernard P. (2008) Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis. Journal of Immunology, 181 (11). pp. 8010-8017. ISSN 0022-1767

Niedbala, W., Cai, B., Wei, X., Patakas, A., Leung, B. P., McInnes, I., and Liew, F. Y (2008) Interleukin 27 attenuates collagen-induced arthritis. Annals of the Rheumatic Diseases, 67 (10). pp. 1474-1479. ISSN 0003-4967 (doi:10.1136/ard.2007.083360)

McKimmie, Clive S. et al. (2008) Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. Journal of Immunology, 181 (5). pp. 3353-3363. ISSN 0022-1767

Xu, Damo et al. (2008) IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proceedings of the National Academy of Sciences of the United States of America, 105 (31). pp. 10913-10918. ISSN 0027-8424 (doi:10.1073/pnas.0801898105)

Grespan, Renata, Fukada, Sandra Y., Lemos, Henrique P., Vieira, Silvio M., Napimoga, Marcelo H., Teixeira, Mauro M., Fraser, Alasdair R. , Liew, Foo Y., McInnes, Iain B. , and Cunha, Fernando Q. (2008) CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis. Arthritis and Rheumatism, 58 (7). pp. 2030-2040. ISSN 0004-3591 (doi:10.1002/art.23597)

Culshaw, S.E., Millington, O.R., Brewer, J.M., and McInnes, I. (2008) Murine neutrophils present class II restricted antigen. Immunology Letters, 118 (1). pp. 49-54. ISSN 0165-2478 (doi:10.1016/j.imlet.2008.02.008)

Miller, Ashley M., Xu, Damo, Asquith, Darren L., Denby, Laura, Li, Yubin, Sattar, Naveed, Baker, Andrew H., McInnes, Iain B., and Liew, Foo Y. (2008) IL-33 reduces the development of atherosclerosis. Journal of Experimental Medicine, 205 (2). pp. 339-346. ISSN 0022-1007 (doi:10.1084/jem.20071868 )

Brennan, FM, and McInnes, I (2008) Evidence that cytokines play a role in rheumatoid arthritis. Journal of Clinical Investigation, 118 (11). pp. 3537-3545.

Harnett, M et al. (2008) The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis. Annals of the Rheumatic Diseases, 67 (4). pp. 518-523. ISSN 0003-4967 (doi:10.1136/ard.2007.073502)

Hothersall, EJ et al. (2008) Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax, 63 (12). pp. 1070-1075. ISSN 0040-6376 (doi:10.1136/thx.2008.100198)

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151 (1). pp. 114-122. ISSN 0009-9104

Wong, S., Macrae, V.E., Gracie, J.A., McInnes, I., Galea, P., Gardner-Medwin, J., and Ahmed, S.F. (2008) Inflammatory cytokines in juvenile idiopathic arthritis: Effects on physical growth and the insulin-like-growth factor axis. Growth Hormone and IGF Research, 18 (5). pp. 369-378. ISSN 1096-6374 (doi:10.1016/j.ghir.2008.01.006 )

2007

Verri, Waldiceu A., Cunha, Thiago M., Ferreira, Sérgio H., Wei, Xiaoqing , Leung, Bernard P., Fraser, Alasdair, McInnes, Iain B., Liew, Foo Y., and Cunha, Fernando Q. (2007) IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. European Journal of Immunology, 37 (12). pp. 3373-3380. ISSN 0014-2980 (doi:10.1002/eji.200737488)

Cai, Beilei, Hueber, Axel J., Leung, Bernard P., Liew, Foo Y., McInnes, Iain B., Niedbala, Wanda, and Wei, Xiao-qing (2007) IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. European Journal of Immunology, 37 (11). pp. 3021-3029. ISSN 0014-2980 (doi:10.1002/eji.200737810)

Komai-Koma, Mousa, Li, Yubin , Liew, Foo Y., McInnes, Iain B., McKenzie, Andrew N. J., and Xu, Damo (2007) IL-33 is a chemoattractant for human Th2 cells. European Journal of Immunology, 37 (10). pp. 2779-2786. ISSN 0014-2980 (doi:10.1002/eji.200737547)

Asquith, DL, and McInnes, IB (2007) Emerging cytokine targets in rheumatoid arthritis. Current Opinion in Rheumatology, 19 . pp. 246-251.

Boyle, D et al. (2007) Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: Standardization and consistency across centers. Journal of Rheumatology, 34 . pp. 620-622.

Capell, HA et al. (2007) Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to sulfasalazine: results from the double-blind placebo-controlled MASCOT study. Annals of the Rheumatic Diseases, 66 . pp. 235-241. ISSN 0003-4967 (doi:10.1136/ard.2006.057133)

Dunning, L, Elias-Jones, I, Ferrell, WR, Gracie, JA, Hembrough, T, Kelso, EB, Lockhart, JC, and McInnes, IB (2007) Expression and proinflammatory role of proteinase-activated receptor 2 in rheumatoid synovium - Ex vivo studies using a novel proteinase-activated receptor 2 antagonist. Arthritis and Rheumatism, 56 . pp. 765-771. ISSN 0004-3591 (doi:10.1002/art.22423)

Macrae, VE, Wong, SC, Smith, W, Gracie, A, McInnes, I, Galea, P, Gardner-Medwin, J, Farquharson, C, Ahmed, SF, and Ahmed, SF (2007) Cytokine profiling and in vitro studies of murine bone growth using biological fluids from children with juvenile idiopathic arthritis. Clinical Endocrinology, 67 . pp. 442-448. (doi:10.1111/j.1365-2265.2007.02908.x)

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115 (11). E326-E328.

McInnes, IB, and Schett, G (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nature Reviews Immunology, 7 . pp. 429-442. (doi:10.1038/nri2094)

Sattar, N, Crompton, P, Cherry, L, Kane, D, Lowe, G, and McInnes, IB (2007) Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis - A double-blind, placebo-controlled study. Arthritis and Rheumatism, 56 . pp. 831-839. ISSN 0004-3591 (doi:10.1002/art.22447)

2006

Anderson, EJR, McGrath, MA, McInnes, IB, and Thalhamer, T (2006) Interleukin-12 to interleukin 'infinity': the rationale for future therapeutic cytokine targeting. Springer Seminars in Immunopathology, 27 . pp. 425-442. (doi:10.1007/s00281-006-0011-x)

Baeten, D, Bresnihan, B, De, KF, De, RL, Fitzgerald, O, Kruithof, E, McInnes, I, Tak, PP, Vandooren, B, and Veys, EM (2006) Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis. Arthritis and Rheumatism, 54 . pp. 1795-1804. ISSN 0004-3591 (doi:10.1002/art.21914)

Baeten, D, Bresnihan, B, Fitzgerald, O, McInnes, IB, Smith, MD, Tak, PP, Ulfgren, AK, and Veale, D (2006) Standardisation of synovial tissue infiltrate analysis: how far have we come? how much further do we need to go? Annals of the Rheumatic Diseases, 65 . pp. 93-100. ISSN 0003-4967 (doi:10.1136/ard.2005.036905)

Connell, L., and McInnes, I.B. (2006) New cytokine targets in inflammatory rheumatic diseases. Best Practice and Research: Clinical Rheumatology, 20 . pp. 865-878. ISSN 1521-6942 (doi:10.1016/j.berh.2006.05.011)

Fitzgerald, O., and McInnes, I. (2006) Spondyloarthropathy: disease at the crossroads of immunity. Best Practice and Research: Clinical Rheumatology, 20 . pp. 949-967. ISSN 1521-6942 (doi:10.1016/j.berh.2006.06.010)

2005

Alvaro, J et al. (2005) A multicentre, randomised, double blind, placebo controlled phase II study of subcutaneous interferon beta-1a in the treatment of patients with active rheumatoid arthritis. Annals of the Rheumatic Diseases, 64 . pp. 64-69. ISSN 0003-4967 (doi:10.1136/ard.2003.020347)

Baeten, D et al. (2005) Synovial tissue analysis in clinical trials. Journal of Rheumatology, 32 . pp. 2481-2484.

Baeten, D, Bresnihan, B, Gerlag, DM, Haringman, JJ, Kraan, MC, McInnes, IB, Smeets, TJM, Tak, PP, and Zwinderman, AH (2005) Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 64 . pp. 834-838. ISSN 0003-4967 (doi:10.1136/ard.2004.029751)

Baslund, B et al. (2005) Targeting interleukin-15 in patients with rheumatoid arthritis - A proof-of-concept study. Arthritis and Rheumatism, 52 . pp. 2686-2692. ISSN 0004-3591 (doi:10.1002/art.21249)

Blackbourn, DJ, Gracie, JA, McInnes, IB, and Rezaee, SAR (2005) Inhibition of neutrophil function by the Kaposi's sarcoma-associated herpesvirus vOX2 protein. AIDS, 19 . pp. 1907-1910.

Chandler, D, Griffiths, CEM, Helliwell, P, Kyle, S, Lewis, J, McHugh, N, McInnes, I, Oliver, S, and Symmons, D (2005) Guideline for anti-TNF-alpha therapy in psoriatic arthritis. Rheumatology, 44 . pp. 390-397. (doi:10.1093/rheumatology/keh514)

Choo-Kang, BSW, Hutchison, S, Nickdel, MB, Bundick, RV, Leishman, AJ, Brewer, JM, McInnes, IB, and Garside, P (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26 . pp. 518-522. (doi:10.1016/j.it.2005.07.007)

Culshaw, S, Leung, BP, Gracie, JA, Campbell, CC, Thomson, D, Gemmell, C, Liew, FY, and McInnes, IB (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35 . pp. 1438-1444. (doi:10.1002/ejui.200425661)

Gracie, JA et al. (2005) Disease association of two distinct interleukin-18 promoter polymorphisms in Caucasian rheumatoid arthritis patients. Genes and Immunity, 6 . pp. 211-216. (doi:10.1038/sj.gene.6364183)

Gracie, JA, Liew, FY, and McInnes, IB (2005) Interleukin-18: A therapeutic target in rheumatoid arthritis? Commentary. Arthritis Research and Therapy, 7 . pp. 38-41.

Kane, D, Lockhart, JC, Balint, PV, Mann, C, Ferrell, WR, and McInnes, I (2005) Protective effect of sensory denervation in inflammatory arthritis (evidence of regulatory neuroimmune pathways in the arthritic joint). Annals of the Rheumatic Diseases, 64 (2). pp. 325-327. ISSN 0003-4967

Liew, FY, and McInnes, I (2005) A fork in the pathway to inflammation and arthritis. Nature Medicine, 11 (6). pp. 601-602.

Liew, FY, and McInnes, IB (2005) Cytokine networks - towards new therapies for rheumatoid arthritis. Nature Clinical Practice Rheumatology, 1 . pp. 31-39. (doi:10.1038/ncprheum0020)

McInnes, I (2005) Rheumatoid arthritis: of therapies and strategies. Current Opinion in Rheumatology, 17 (3). pp. 271-273.

McInnes, IB, and Sattar, N (2005) Vascular comorbidity in rheumatoid arthritis: potential mechanisms and solutions. Current Opinion in Rheumatology, 17 . pp. 286-292.

2004

McInnes, I.B., and Gracie, J.A. (2004) Targeting cytokines beyond tumor necrosis factor-alpha and interleukin-1 in rheumatoid arthritis. Current Rheumatology Reports, 6 . pp. 336-342. ISSN 1523-3774

McInnes, I.B., and Gracie, J.A. (2004) Interleukin-15: a new cytokine target for the treatment of inflammatory diseases. Current Opinion in Pharmacology, 4 (4). pp. 392-397. ISSN 1471-4892 (doi:10.1016/j.coph.2004.04.003)

Leung, B.P., Xu, D., Culshaw, S., McInnes, I.B., and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173 (1). pp. 145-150. ISSN 0022-1767

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I.B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173 (1). pp. 151-156. ISSN 0022-1767

Harnett, W., McInnes, I.B., and Harnett, M.M. (2004) ES-62, a filarial nematode-derived immunomodulator with anti-inflammatory potential. Immunology Letters, 94 (1-2). pp. 27-33. ISSN 0165-2478 (doi:10.1016/j.imlet.2004.04.008)

McCarey, D.W., McInnes, I.B., Madhok, R., Hampson, R., Scherbakov, O., Ford, I., Capell, H., and Sattar, N. (2004) Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial. Lancet, 363 (9426). pp. 2015-2021. ISSN 0140-6736 (doi:10.1016/S0140-6736(04)16449-0)

McKay, A., Leung, B.P., McInnes, I.B., Thomson, N.C., and Liew, F.Y. (2004) A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. Journal of Immunology, 172 (5). pp. 2903-2908. ISSN 0022-1767

Wilson, R., Moor, J., Jenkins, C., Miller, H., Walker, J.J., McLean, M.A., Norman, J., and McInnes, I.B. (2004) Abnormal first trimester serum interleukin 18 levels are associated with a poor outcome in women with a history of recurrent miscarriage. American Journal of Reproductive Immunology, 51 (2). pp. 156-159. ISSN 1046-7408 (doi:10.1046/j.8755-8920.2003.00126.x)

Alessandri, C, Barone, F, Blades, MC, Bombardieri, M, Conigliaro, P, McInnes, IB, Pittoni, V, Pitzalis, C, Priori, R, and Valesini, G (2004) Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjogren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Research and Therapy, 6 . R447-R456. (doi:10.1186/ar1209)

Bombardieri, M., Barone, F., Pittoni, P., Alessandri, C., Conigliaro, P., Blades, M.C., Priori, R., McInnes, I.B., Valesini, G., and Pitzalis, C. (2004) Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Research and Therapy, 6 . R447-R456. ISSN 1478-6362 (doi:10.1186/ar1209)

Capell, H, Madhok, R, McCarey, D, McInnes, I, and Sattar, N (2004) Statins and rheumatoid arthritis - Reply. Lancet, 364 (9448). p. 1855.

Harnett, W., Harnett, M.M., Leung, B.P., Gracie, J., and McInnes, I.B. (2004) The anti-inflammatory potential of the filarial nematode secreted product, ES-62. Current Topics in Medicinal Chemistry, 4 (5). pp. 553-559. ISSN 1568-0266 (doi:10.2174/1568026043451212)

2003

Sattar, N., McCarey, D.W., Capell, H., and McInnes, I.B. (2003) Explaining how "high-grade" systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation, 108 (24). pp. 2957-2963. ISSN 1524-4539 (doi:10.1161/01.CIR.0000099844.31524.05)

McInnes, I.B., Gracie, J.A., Harnett, M., Harnett, W., and Liew, F.Y. (2003) New strategies to control inflammatory synovitis: interleukin 15 and beyond. Annals of the Rheumatic Diseases, 62 (2). pp. 51-54. ISSN 0003-4967 (doi:10.1136/ard.62.suppl_2.ii51)

McInnes, I.B., Leung, B.P., Harnett, M., Gracie, J.A., Liew, F., and Harnett, W. (2003) A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62. Journal of Immunology, 171 (4). pp. 2127-2133. ISSN 0022-1767

Wilson, R., Moore, J., Jenkins, C., Miller, H., Maclean, M.A., McInnes, I.B., and Walker, J.J. (2003) Abnormal IL-2 receptor levels in non-pregnant women with a history of recurrent miscarriage. Human Reproduction, 18 (7). pp. 1529-1530. ISSN 0268-1161 (doi:10.1093/humrep/deg287)

Gracie, J.A., Robertson, S.E., and McInnes, I.B. (2003) Interleukin-18. Journal of Leukocyte Biology, 73 (2). pp. 213-224. ISSN 0741-5400 (doi:10.1189/jlb.0602313)

Campbell, C et al. (2003) A novel anti-inflammatory role for simvastatin in inflammatory arthritis. Journal of Immunology, 170 . pp. 1524-1530.

Gracie, JA, Komai-Koma, M, Liew, FY, McInnes, IB, Thomson, N, Wei, XQ, and Xu, DM (2003) Chemoattraction of human T cells by IL-18. Journal of Immunology, 170 . pp. 1084-1090.

McInnes, I.B. (2003) Leukotrienes, mast cells, and T cells. Arthritis Research and Therapy, 5 (6). pp. 288-289. ISSN 1478-6362 (doi:10.1186/ar1017)

2002

Guillen, C, McInnes, I.B., Vaughan, D.M., Kommajosyula, S., Van Berkel, P.H.C,, Leung, B.P., Aguila, A., and Brock, J.H. (2002) Enhanced Th1 response to Staphylococcus aureas infection in human lactoferrin-transgenic mice. Journal of Immunology, 168 (8). pp. 3950-3957. ISSN 0022-1767

Balint, PV, Kane, D, Hunter, J, McInnes, IB, Field, M, and Sturrock, RD (2002) Ultrasound guided versus conventional joint and soft tissue fluid aspiration in rheumatology practice: A pilot study. Journal of Rheumatology, 29 . pp. 2209-2213.

Balint, PV, Kane, D, Wilson, H, McInnes, IB, and Sturrock, RD (2002) Ultrasonography of entheseal insertions in the lower limb in spondyloarthropathy. Annals of the Rheumatic Diseases, 61 . pp. 905-910. ISSN 0003-4967

Boumpas, DT, Ikeuchi, H, Kaneko, Y, Kuroiwa, T, McInnes, IB, Nojima, Y, Ota, F, Tanaka, T, Tsukada, Y, and Ueki, K (2002) Human platelets stimulate mesangial cells to produce monocyte chemoattractant protein-1 via the CD40/CD40 ligand pathway and may amplify glomerular injury. Journal of the American Society of Nephrology, 13 . pp. 2488-2496. (doi:10.1097/01.ASN.0000029588.07166.20)

Gracie, JA, Leung, BP, and McInnes, IB (2002) Novel pathways that regulate tumor necrosis factor-alpha production in rheumatoid arthritis. Current Opinion in Rheumatology, 14 . pp. 270-275.

Leung, BP, Conacher, M, Hunter, D, McInnes, IB, Liew, FY, and Brewer, JM (2002) A novel dendritic cell-induced model of erosive inflammatory arthritis: Distinct roles for dendritic cells in T cell activation and induction of local inflammation. Journal of Immunology, 169 . pp. 7071-7077.

Liew, FY, and McInnes, IB (2002) Role of interleukin 15 and interleukin 18 in inflammatory response. Annals of the Rheumatic Diseases, 61 . pp. 100-102. ISSN 0003-4967

Liew, FY, and McInnes, IB (2002) The role of innate mediators in inflammatory response. Molecular Immunology, 38 . pp. 887-890.

2001

Arthur, HML, Leung, BP, Liew, FY, McInnes, IB, and Wei, XQ (2001) Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. Journal of Immunology, 166 . pp. 517-521.

Boumpas, DT et al. (2001) IL-10 improves skin disease and modulates endothelial activation and leukocyte effector function in patients with psoriatic arthritis. Journal of Immunology, 167 . pp. 4075-4082.

Campbell, C, Canetti, CA, Culshaw, S, Cunha, F, Gracie, JA, Hunter, D, Leung, BP, Liew, FY, and McInnes, IB (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167 . pp. 2879-2886.

Capell, H, Hamilton, J, Madhok, R, Mcinnes, I, and Wilson, H (2001) The hip or not. Journal of Rheumatology, 28 (6). pp. 1398-1400.

Capell, HA, Hamilton, J, Hunter, JA, Madhok, R, McInnes, I, Porter, D, and Thomson, EA (2001) Comparative study of intramuscular gold and methotrexate in a rheumatoid arthritis population from a socially deprived area. Annals of the Rheumatic Diseases, 60 (6). pp. 566-572. ISSN 0003-4967

Capell, HA, Hamilton, JD, Madhok, R, McInnes, I, and Wilson, HE (2001) TNF alpha blockade in rheumatoid arthritis - Time for caution or enthusiasm? Scottish Medical Journal, 46 (3). pp. 67-70.

Esfandiari, E, McInnes, IB, Lindop, G, Huang, FP, Field, M, Komai-Koma, M, Wei, XQ, and Liew, FY (2001) A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. Journal of Immunology, 167 . pp. 5338-5347.

Gao, BM, Gracie, JA, Guan, H, Leung, BP, Liew, FY, McInnes, IB, Niedbala, W, Orchardson, M, Paterson, GK, and Wei, XQ (2001) The sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo. Journal of Immunology, 167 . pp. 277-282.

McCarey, DW, McInnes, I, and Sattar, N (2001) The antiinflammatory effects of statins. New England Journal of Medicine, 345 (16). pp. 1209-1210. ISSN 0028-4793

McInnes, IB (2001) Rheumatoid arthritis - From bench to bedside. Rheumatic Disease Clinics of North America, 27 . pp. 373-387.

2000

Leung, BP, Liew, FY, and McInnes, IB (2000) Cell-cell interactions in synovitis - Interactions between T lymphocytes and synovial cells. Arthritis Research, 2 (5). pp. 374-378.

This list was generated on Fri Jul 25 15:01:35 2014 BST.
Number of items: 207.

Article

Nurmohamed, Michael T, Jamnitski, Anna, Symmons, Deborah, Peters, Mike Johannes Leonardus, Sattar, Naveed, and McInnes, Iain (2014) Response to: 'The influence of inflammation in the development of subclinical atherosclerosis in psoriatic arthritis' by Gonzalez-Gay et al. Annals of the Rheumatic Diseases, 73 (5). e28. ISSN 0003-4967 (doi:10.1136/annrheumdis-2014-205174)

Rice, Gillian I et al. (2014) Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling. Nature Genetics, 46 (5). pp. 503-509. ISSN 1061-4036 (doi:10.1038/ng.2933)

Patterson, H., Nibbs, R., McInnes, I., and Siebert, S. (2014) Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases. Clinical and Experimental Immunology, 176 (1). pp. 1-10. ISSN 0009-9104 (doi:10.1111/cei.12248)

Dale, J., Purves, D., McConnachie, A., McInnes, I., and Porter, D. (2014) Tightening up? Impact of musculoskeletal ultrasound disease activity assessment on early rheumatoid arthritis patients treated using a treat to target strategy. Arthritis Care and Research, 66 (1). pp. 19-26. ISSN 2151-464X (doi:10.1002/acr.22218)

Dougados, M. et al. (2014) Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA). Annals of the Rheumatic Diseases, 73 (1). pp. 62-68. ISSN 0003-4967 (doi:10.1136/annrheumdis-2013-204223)

Frleta, Marina, Siebert, Stefan, and McInnes, Iain B. (2014) The interleukin-17 pathway in psoriasis and psoriatic arthritis: disease pathogenesis and possibilities of treatment. Current Rheumatology Reports, 16 (414). ISSN 1523-3774 (doi:10.1007/s11926-014-0414-y)

McInnes, I.B. et al. (2014) Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Annals of the Rheumatic Diseases, 73 (2). pp. 349-356. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-202646)

Paul, L., Rafferty, D., Marshall-Mckenna, R., Gill, J.M.R., McInnes, I., Porter, D., and Woodburn, J. (2014) Oxygen cost of walking, physical activity, and sedentary behaviours in rheumatoid arthritis. Scandinavian Journal of Rheumatology, 43 (1). pp. 28-34. ISSN 0300-9742 (doi:10.3109/03009742.2013.802009)

Turner, Deborah E., Hyslop, Elaine, Barn, Ruth, McInnes, Iain B., Steultjens, Martijn P.M., and Woodburn, James (2014) Metatarsophalangeal joint pain in psoriatic arthritis: a cross-sectional study. Rheumatology, 53 (4). pp. 737-740. ISSN 1462-0324 (doi:10.1093/rheumatology/ket435)

Lappin, D.F., Apatzidou, D., Quirke, A.M., Oliver-Bell, J., Butcher, J.P., Kinane, D.F., Riggio, M.P., Venables, P., McInnes, I.B., and Culshaw, S. (2013) Influence of periodontal disease, porphyromonas gingivalisand cigarette smoking on systemic anti-citrullinated peptide antibody titres. Journal of Clinical Periodontology, 40 (10). pp. 907-915. ISSN 0303-6979 (doi:10.1111/jcpe.12138)

van den Berg, W.B., and McInnes, I.B. (2013) Th17 cells and IL-17 A—Focus on immunopathogenesis and immunotherapeutics. Seminars in Arthritis and Rheumatism, 43 (2). pp. 158-170. ISSN 0049-0172 (doi:10.1016/j.semarthrit.2013.04.006)

Robertson, J., Peters, M.J., McInnes, I.B., and Sattar, N. (2013) Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm. Nature Reviews Rheumatology, 9 (9). pp. 513-523. ISSN 1759-4790 (doi:10.1038/nrrheum.2013.91)

Miller, A.M., Gilchrist, D.S., Nijjar, J., Araldi, E., Ramirez, C.M., Lavery, C.A., Fernandez-Hernando, C., McInnes, I., and Kurowska-Stolarska, M. (2013) MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis. PLoS ONE, 8 (8). e72324. ISSN 1932-6203 (doi:10.1371/journal.pone.007232)

McInnes, I.B. et al. (2013) Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial. Lancet, 382 (9894). pp. 780-789. ISSN 1474-547X (doi:10.1016/S0140-6736(13)60594-2)

Schett, G., Elewaut, D., McInnes, I.B., Dayer, J.-M., and Neurath, M.F. (2013) How cytokine networks fuel inflammation: toward a cytokine-based disease taxonomy. Nature Medicine, 19 (7). pp. 822-824. ISSN 1078-8956 (doi:10.1038/nm.3260)

Weir, Robin A.P. et al. (2013) Response to letter regarding article, "Galectin-3 and cardiac function in survivors of acute myocardial infarction". Circulation: Heart Failure, 6 (4). e58. ISSN 1941-3289 (doi:10.1161/CIRCHEARTFAILURE.113.000382)

Kapoor, S.R., Filer, A., Fitzpatrick, M.A., Fisher, B.A., Taylor, P.C., Buckley, C.D., McInnes, I.B., Raza, K., and Young, S.P. (2013) Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis. Arthritis and Rheumatism, 65 (6). pp. 1448-1456. ISSN 0004-3591 (doi:10.1002/art.37921)

Weir, Robin A.P. et al. (2013) Galectin-3 and cardiac function in survivors of acute myocardial infarction. Circulation: Heart Failure, 6 (3). pp. 492-498. ISSN 1941-3289 (doi:10.1161/CIRCHEARTFAILURE.112.000146)

Villeneuve, E. et al. (2013) Republished: a systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Postgraduate Medical Journal, 89 (1050). pp. 231-240. ISSN 0032-5473 (doi:10.1136/postgradmedj-2011-201063rep)

van der Heijde, D. et al. (2013) EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria. Annals of the Rheumatic Diseases, 72 (4). pp. 479-481. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-202779)

O'Shea, J.J., Laurence, A., and McInnes, I.B. (2013) Back to the future: oral targeted therapy for RA and other autoimmune diseases. Nature Reviews Rheumatology, 9 (3). pp. 173-182. ISSN 1759-4790 (doi:10.1038/nrrheum.2013.7)

Villeneuve, E. et al. (2013) A systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Annals of the Rheumatic Diseases, 72 (1). pp. 13-22. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-201063)

Wagner, C.L. et al. (2013) Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab. Annals of the Rheumatic Diseases, 72 (1). pp. 83-88. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-201697)

Asquith, D.L. et al. (2013) The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release. Annals of the Rheumatic Diseases, 72 (12). pp. 2024-2031. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-202872)

Coates, L.C. et al. (2013) The 2012 BSR and BHPR guideline for the treatment of psoriatic arthritis with biologics. Rheumatology, 52 (10). pp. 1754-1757. ISSN 1462-0324 (doi:10.1093/rheumatology/ket187)

Crilly, A., Palmer, H.S., Nickdel, M.B., Dunning, L., Lockhart, J.C., Plevin, R., McInnes, I.B., and Ferrell, W.R. (2013) Immunomodulatory role of proteinase-activated receptor-2. Annals of the Rheumatic Diseases, 71 (9). pp. 1559-1566. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200869)

Jamnitski, A., Symmons, D., Peters, M.J.L., Sattar, N., McInnes, I., and Nurmohamed, M.T. (2013) Cardiovascular comorbidities in patients with psoriatic arthritis: a systematic review. Annals of the Rheumatic Diseases, 72 (2). pp. 211-216. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-201194)

Kavanaugh, A. et al. (2013) Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study. Annals of the Rheumatic Diseases, 72 (11). pp. 1777-1785. ISSN 0003-4967 (doi:10.1136/annrheumdis-2012-202035)

McInnes, I.B., Combe, B., and Burmester, G. (2013) Understanding the patient perspective: results of the rheumatoid arthritis: insights, strategies and expectations (RAISE) patient needs survey. Clinical and Experimental Rheumatology, 31 (3). pp. 350-7. ISSN 0392-856X

Millar, N., Murrell, G.A.C., and McInnes, I. (2013) Alarmins in tendinopathy: unravelling new mechanisms in a common disease. Rheumatology, 52 (5). pp. 769-779. ISSN 1462-0324

Miller, Ashley M., Gilchrist, Derek S., Nijjar, Jagtar, Araldi, Elisa, Ramirez, Cristina M., Lavery, Christopher A., Fernández-Hernando, Carlos, McInnes, Iain B., and Kurowska-Stolarska, Mariola (2013) MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice. PLoS ONE, 8 (8). e72324. ISSN 1932-6203 (doi:10.1371/journal.pone.0072324)

Nijjar, J., Tindell, A., McInnes, I.B., and Siebert, S. (2013) Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis. Rheumatology, 52 (9). pp. 1556-1562. ISSN 1462-0324 (doi:10.1093/rheumatology/ket225)

Steven, Rachael, Crilly, Anne, Lockhart, John C., Ferrell, William R., and McInnes, Iain B. (2013) Proteinase-activated receptor-2 modulates human macrophage differentiation andeffector function. Innate Immunity, 19 (6). pp. 663-672. ISSN 1753-4259 (doi:10.1177/1753425913479984)

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32 (11). pp. 2569-2579. ISSN 1079-5642 (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7 (11). e49715. ISSN 1932-6203 (doi:10.1371/journal.pone.0049715)

Miller, Ashley M. et al. (2012) Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? PLoS ONE, 7 (10). e47830. ISSN 1932-6203 (doi:10.1371/journal.pone.0047830)

Haneklaus, M., Gerlic, M., Kurowska-Stolarska, M., Rainey, A.-A., Pich, D., McInnes, I.B., Hammerschmidt, W., O'Neill, L.A.J., and Masters, S.L. (2012) Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1 production. Journal of Immunology, 189 (8). pp. 3795-3799. ISSN 0022-1767 (doi:10.4049/jimmunol.1200312)

Keystone, E. C., Wang, M. M., Layton, M., Hollis, S., and McInnes, I.B. (2012) Clinical evaluation of the efficacy of the P2X7 purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine. Annals of the Rheumatic Diseases, 71 (10). pp. 1630-1635. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-143578)

Utriainen, Lotta, Firmin, Dawn, Wright, Pamela, Cerovic, Vuk, Breban, Maxime, McInnes, Iain, and Milling, Simon (2012) Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis. Arthritis and Rheumatism, 64 (10). pp. 3199-3209. ISSN 0004-3591 (doi:10.1002/art.34561)

Weir, Robin A.P., Miller, Ashley M., Petrie, Colin J., Clements, Suzanne, Steedman, Tracey, Dargie, Henry J., Squire, Iain B., Ng, Leong L., McInnes, Iain B., and McMurray, John J.V. (2012) Interleukin-21 – a biomarker of importance in predicting myocardial function following acute infarction? Cytokine, 60 (1). pp. 220-225. ISSN 1043-4666 (doi:10.1016/j.cyto.2012.06.002)

Singh, M.D. et al. (2012) Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis. American Journal of Pathology, 181 (4). pp. 1158-1164. ISSN 0002-9440 (doi:10.1016/j.ajpath.2012.06.042)

Tindell, A.G., Kelso, E.B., Ferrell, W.R., Lockhart, J.C., Walsh, D.A., Dunning, L., and McInnes, I.B. (2012) Correlation of protease-activated receptor-2 expression and synovitis in rheumatoid and osteoarthritis. Rheumatology International, 32 (10). pp. 3077-3086. ISSN 0172-8172 (doi:10.1007/s00296-011-2102-9)

Komai-Koma, M. et al. (2012) Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice. Allergy, 67 (9). pp. 1118-1126. ISSN 0105-4538 (doi:10.1111/j.1398-9995.2012.02859.x)

Kavanaugh, A. et al. (2012) Golimumab in psoriatic arthritis: one-year clinical efficacy, radiographic, and safety results from a phase III, randomized, placebo-controlled trial. Arthritis and Rheumatism, 64 (8). pp. 2504-2517. ISSN 0004-3591 (doi:10.1002/art.34436)

Crilly, A. et al. (2012) PAR2 expression in peripheral blood monocytes of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71 (6). pp. 1049-1054. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200703)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119 (11). pp. 2545-2551. ISSN 0006-4971 (doi:10.1182/blood-2011-09-378356)

Baxter, D., McInnes, I.B., and Kurowska-Stolarska, M. (2012) Novel regulatory mechanisms in inflammatory arthritis: a role for microRNA. Immunology and Cell Biology, 90 (3). pp. 288-292. ISSN 0818-9641 (doi:10.1038/icb.2011.114)

Frleta, M., King, V., Reilly, J.H., Gilchrist, D.S., Tornehave, D., Lundsgaard, D., Miller, A.M., and McInnes, I.B. (2012) Expression of IL-21 receptor in synovial tissue and blood of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71 (Sup. 1). A83. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-201238.25)

Gossec, L. et al. (2012) European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Annals of the Rheumatic Diseases, 71 (1). pp. 4-12. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200350)

Henningsson, L., Jirholt, P., Bogestal, Y.R., Eneljung, T., Adiels, M., Lindholm, C., McInnes, I., Bulfone-Paus, S., Lerner, U.H., and Gjertsson, I. (2012) Interleukin 15 mediates joint destruction in Staphylococcus aureus arthritis. Journal of Infectious Diseases, 206 (5). pp. 687-696. ISSN 0022-1899 (doi:10.1093/infdis/jis295)

Johnsson, H., McInnes, I.B., and Sattar, N. (2012) Cardiovascular and metabolic risks in psoriasis and psoriatic arthritis: pragmatic clinical management based on available evidence. Annals of the Rheumatic Diseases, 71 (4). pp. 480-483. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200567)

Kerekes, G., Soltész, P., Nurmohamed, M.T., Gonzalez-Gay, M.A., Turiel, M., Végh, E., Shoenfeld, Y., McInnes, I., and Szekanecz, Z. (2012) Validated methods for assessment of subclinical atherosclerosis in rheumatology. Nature Reviews Rheumatology, 8 (4). pp. 224-234. ISSN 1759-4790 (doi:10.1038/nrrheum.2012.16)

Lories, R.J., and McInnes, I.B. (2012) Primed for inflammation: enthesis-resident T cells. Nature Medicine, 18 (7). pp. 1018-1019. ISSN 1078-8956 (doi:10.1038/nm.2854)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84 (14). pp. 5968-5975. ISSN 0003-2700 (doi:10.1021/ac3006445)

Millar, N.L., Reilly, J.H., Kerr, S.C., Campbell, A.L., Little, K.J., Leach, W.J., Rooney, B.P., Murrell, G.A.C., and McInnes, I.B. (2012) Hypoxia: a critical regulator of early human tendinopathy. Annals of the Rheumatic Diseases, 71 (2). pp. 302-310. ISSN 0003-4967 (doi:10.1136/ard.2011.154229)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7 (11). e49715. ISSN 1932-6203 (doi:10.1371/journal.pone.0049715)

Steinman, L., Merrill, J.T., McInnes, I.B., and Peakman, M. (2012) Optimization of current and future therapy for autoimmune diseases. Nature Medicine, 18 (1). pp. 59-65. ISSN 1078-8956 (doi:10.1038/nm.2625)

Wenink, M.H., Santegoets, K.C.M., Platt, A.M., van den Berg, W.B., van Riel, P.L.C.M., Garside, P., Radstake, T.R.D.J., and McInnes, I.B. (2012) Abatacept modulates proinflammatory macrophage responses upon cytokine-activated T cell and Toll-like receptor ligand stimulation. Annals of the Rheumatic Diseases, 71 (1). pp. 80-83. ISSN 0003-4967 (doi:10.1136/annrheumdis-2011-200348)

Xuzhu, G., Komai-Koma, M., Leung, B.P., Howe, H.S., McSharry, C., McInnes, I.B., and Xu, D. (2012) Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. Annals of the Rheumatic Diseases, 71 (1). pp. 129-135. ISSN 0003-4967 (doi:10.1136/ard.2011.149831)

McInnes, I.B., and Schett, G. (2011) The pathogenesis of rheumatoid arthritis. New England Journal of Medicine, 365 (23). pp. 2205-2219. ISSN 0028-4793 (doi:10.1056/NEJMra1004965)

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! FEBS Letters, 585 (23). pp. 2640-3648. ISSN 0014-5793 (doi:10.1016/j.febslet.2011.04.069)

Wenink, M.H., Santegoets, K.C.M., Butcher, J., van Bon, L., Lamers-Karnebeek, F.G.M., van den Berg, W.B., van Riel, P.L.C.M., McInnes, I.B., and Radstake, T.R.D.J. (2011) Impaired dendritic cell proinflammatory cytokine production in psoriatic arthritis. Arthritis and Rheumatism, 63 (11). pp. 3313-3322. ISSN 0004-3591 (doi:10.1002/art.30577)

Welsh, Paul et al. (2011) Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arteriosclerosis, Thrombosis and Vascular Biology, 31 (10). pp. 2338-2344. ISSN 1079-5642 (doi:10.1161/ATVBAHA.111.231795)

Hueber, Axel J., Alves-Filho, Jose C., Asquith, Darren L., Michels, Chesney , Millar, Neal L., Reilly, James H., Graham, Gerry J., Liew, Foo Y., Miller, Ashley M., and McInnes, Iain B. (2011) IL-33 induces skin inflammation with mast cell and neutrophil activation. European Journal of Immunology, 41 (8). pp. 2229-2237. ISSN 0014-2980 (doi:10.1002/eji.201041360)

Conigliaro, P., Benson, R.A., Patakas, A., Kelly, S.M., Valesini, G., Homdahl, R., Brewer, J.M., McInnes, I.B., and Garside, P. (2011) Characterization of the anti-collagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63 (8). pp. 2299-2308. ISSN 0004-3591 (doi:10.1002/art.30413)

Conigliaro, Paola, Benson, Robert A., Patakas, Agapitos, Kelly, Sharon M., Valesini, Guido, Holmdahl, Rikard, Brewer, James M., McInnes, Iain B., and Garside, Paul (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63 (8). pp. 2299-2308. ISSN 0004-3591 (doi:10.1002/art.30413)

Kurowska-Stolarska, Mariola et al. (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proceedings of the National Academy of Sciences of the United States of America, 108 (27). pp. 11193-11198. ISSN 0027-8424 (doi:10.1073/pnas.1019536108)

Patakas, Agapitos, Platt, Andrew M., Butcher, John P., Maffia, Pasquale, McInnes, Iain B., Brewer, James M., Garside, Paul, and Benson, Robert A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138 (1). pp. 38-46. ISSN 0165-2478 (doi:10.1016/j.imlet.2011.03.002)

Zaiss, Mario M. et al. (2011) IL-33 Shifts the Balance from Osteoclast to Alternatively Activated Macrophage Differentiation and Protects from TNF-α–Mediated Bone Loss. Journal of Immunology, 186 (11). pp. 6097-6105. ISSN 0022-1767 (doi:10.4049/jimmunol.1003487)

Welsh, P. et al. (2011) Vitamin D deficiency is common in patients with RA and linked to disease activity, but circulating levels are unaffected by TNF blockade: results from a prospective cohort study. Annals of the Rheumatic Diseases, 70 (6). pp. 1165-1167. ISSN 0003-4967 (doi:10.1136/ard.2010.137265)

Hansell, Chris A. H., Schiering, Chris, Kinstrie, Ross, Ford, Laura, Bordon, Yvonne, McInnes, Iain B., Goodyear, Carl S., and Nibbs, Robert J.B. (2011) Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice. Blood, 117 (20). pp. 5413-5424. ISSN 0006-4971 (doi:10.1182/blood-2010-11-317115)

Krishnadas, R., Mallon, V., McInnes, I., and Cavanagh, J. (2011) Correlates of depression and quality of life in patients with inflammatory arthritides. European Psychiatry, 26 . p. 383. ISSN 0924-9338 (doi:10.1016/S0924-9338(11)72091-0)

Norman, J.E., Yuan, M., Anderson, L., Howie, F., Harold, G., Young, A., Jordan, F., McInnes, I., and Harnett, M.M. (2011) Effect of prolonged in vivo administration of progesterone in pregnancy on myometrial gene expression, peripheral blood leukocyte activation, and circulating steroid hormone levels. Reproductive Sciences, 18 (5). pp. 435-446. ISSN 1933-7191 (doi:10.1177/1933719110395404)

Culshaw, Shauna, McInnes, Iain B., and Liew, Foo Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38 (S11). pp. 106-113. ISSN 0303-6979 (doi:10.1111/j.1600-051X.2010.01669.x)

Codullo, Veronica et al. (2011) An investigation of the inflammatory cytokine and chemokine network in systemic sclerosis. Annals of the Rheumatic Diseases, 70 (6). pp. 1115-1121. ISSN 0003-4967 (doi:10.1136/ard.2010.137349 )

Miller, A., and McInnes, Iain (2011) Cytokines as therapeutic targets to reduce cardiovascular risk in chronic inflammation. Current Pharmaceutical Design, 17 (1). pp. 1-8. ISSN 1381-6128 (doi:10.2174/138161211795049796)

Asquith, D.L., Miller, A.M., Reilly, J.H., Kerr, S., Welsh, P., Sattar, N., and McInnes, I.B. (2011) Simultaneous activation of the liver X receptors (LXR and LXR) drives murine collagen-induced arthritis disease pathology. Annals of the Rheumatic Diseases, 70 (12). pp. 2225-2228. ISSN 0003-4967 (doi:10.1136/ard.2011.152652)

Bombardieri, M., Kam, N.-W., Brentano, F., Choi, K., Filer, A., Kyburz, D., McInnes, I.B., Gay, S., Buckley, C., and Pitzalis, C. (2011) A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells. Annals of the Rheumatic Diseases, 70 (10). pp. 1857-1865. ISSN 0003-4967 (doi:10.1136/ard.2011.150219)

Crilly, A., Robertson, S.E., Reilly, J.H., Gracie, J.A., Lai, W.-Q., Leung, B.P., Life, P.F., and McInnes, I.B. (2011) Phosphodiesterase 4 (PDE4) regulation of proinflammatory cytokine and chemokine release from rheumatoid synovial membrane. Annals of the Rheumatic Diseases, 70 (6). pp. 1130-1137. ISSN 0003-4967 (doi:10.1136/ard.2010.134825)

Laing, S., Hernandez-Santana, A., Sassmannshausen, J., Asquith, D.L., McInnes, I.B., Faulds, K., and Graham, D. (2011) Quantitative Detection of Human Tumor Necrosis Factor α by a Resonance Raman Enzyme-Linked Immunosorbent Assay. Analytical Chemistry, 83 (1). pp. 297-302. ISSN 0003-2700 (doi:10.1021/ac1024039)

MacLellan, L.M., Montgomery, J., Sugiyama, F., Kitson, S.M., Thümmler, K., Silverman, G.J., Beers, S.A., Nibbs, R.J.B., McInnes, I.B., and Goodyear, C.S. (2011) Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice. Arthritis and Rheumatism, 63 (12). pp. 3897-3907. ISSN 0004-3591 (doi:10.1002/art.30629)

Pitman, N., Asquith, D.L., Murphy, G., Liew, F.Y., and McInnes, I.B. (2011) Collagen-induced arthritis is not impaired in mast cell-deficient mice. Annals of the Rheumatic Diseases, 70 (6). pp. 1170-1171. ISSN 0003-4967 (doi:10.1136/ard.2010.134528)

Zwerina, K. et al. (2011) Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance. European Journal of Immunology, 42 (2). pp. 413-423. ISSN 0014-2980 (doi:10.1002/eji.201141871)

van de Sande, M. G. H. et al. (2011) Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials. Annals of the Rheumatic Diseases, 70 (3). pp. 423-427. ISSN 0003-4967 (doi:10.1136/ard.2010.139550)

Miller, Ashley M., Asquith, Darren L., Hueber, Axel J., Anderson, Lesley A., Holmes, William M., McKenzie, Andrew N., Xu, Damo, Sattar, Naveed, McInnes, Iain B., and Liew, Foo Y. (2010) Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circulation Research, 107 (5). pp. 650-658. ISSN 0009-7330 (doi:10.1161/CIRCRESAHA.110.218867)

Verri, Waldiceu A. et al. (2010) IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Annals of the Rheumatic Diseases, 69 (9). pp. 1697-1703. ISSN 0003-4967 (doi:10.1136/ard.2009.122655)

Emery, P., Buch, M.H., Östör, A., Kirkham, B., Taylor, P., Estrach, C., Jenkinson, T., McInnes, I., and Porter, D. (2010) Time for treatment targets in rheumatoid arthritis. British Medical Journal, 341 (c4170). p. 267. ISSN 0959-535X (doi:10.1136/bmj.c4170)

Platt, Andrew M., Gibson, Vivienne B., Patakas, Agapitos, Benson, Robert A., Nadler, Steven G., Brewer, James M., McInnes, Iain, and Garside, Paul (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185 (3). pp. 1558-1567. ISSN 0022-1767 (doi:10.4049/jimmunol.1001311 )

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184 (11). pp. 6378-6385. ISSN 0022-1767 (doi:10.4049/jimmunol.0903951)

Hueber, Axel J., Asquith, Darren L., Miller, Ashley M., Reilly, Jim, Kerr, Shauna, Leipe, Jan, Melendez Romero, Alirio J., and McInnes, Iain B. (2010) Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium. Journal of Immunology, 184 (7). pp. 3336-3340. ISSN 0022-1767 (doi:10.4049/jimmunol.0903566)

Xu, Damo et al. (2010) IL-33 exacerbates autoantibody-induced arthritis. Journal of Immunology, 184 (5). pp. 2620-2626. ISSN 0022-1767 (doi:10.4049/jimmunol.0902685)

Asquith, Darren L., Miller, Ashley M., Hueber, Axel J., Liew, Foo Y., Sattar, Naveed, and McInnes, Iain B. (2010) Apolipoprotein E-deficient mice are resistant to the development of collagen-induced arthritis. Arthritis and Rheumatism, 62 (2). pp. 472-477. ISSN 0004-3591 (doi:10.1002/art.27205)

Liew, Foo Y., Pitman, Nick I., and McInnes, Iain B. (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nature Reviews Immunology, 10 (2). pp. 103-110. ISSN 1474-1733 (doi:10.1038/nri2692)

Weir, R.A.P., Miller, A.M., Murphy, G., Clements, S., Steedman, T., Connell, J., McInnes, I., Dargie, H., and McMurray, J.J. (2010) Serum soluble ST2 a potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction. Journal of the American College of Cardiology, 55 (3). pp. 243-250. ISSN 0735-1097 (doi:10.1016/j.jacc.2009.08.047)

Murphy, G.E.J., Xu, D., Liew, F.Y., and McInnes, I.B. (2010) Role of interleukin 33 in human immunopathology. Annals of the Rheumatic Diseases, 69 (Suppl ). pp. 43-47. ISSN 0003-4967 (doi:10.1136/ard.2009.120113)

Cavanagh, J., Paterson, C., McLean, J., Pimlott, S., McDonald, M., Patterson, J., Wyper, D., and McInnes, Iain (2010) Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study. Annals of the Rheumatic Diseases, 69 (6). 1251-U367. ISSN 0003-4967 (doi:10.1136/ard.2009.107912)

Ferrell, W.R., Kelso, E.B., Lockhart, J.C., Plevin, R., and McInnes, I.B. (2010) Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis. Annals of the Rheumatic Diseases, 69 (11). pp. 2051-2054. ISSN 0003-4967 (doi:10.1136/ard.2010.130336)

Fraser, A.R., Perry, M.E., Crilly, A., Reilly, J.H., Hueber, A.J., and McInnes, I.B. (2010) Lipoma arborescens co-existing with psoriatic arthritis releases tumour necrosis factor alpha and matrix metalloproteinase. Annals of the Rheumatic Diseases, 69 (4). pp. 776-777. ISSN 0003-4967 (doi:10.1136/ard.2008.106047)

Hueber, A.J., Asquith, D.L., McInnes, I.B., and Miller, A.M. (2010) Embracing novel cytokines in RA – complexity grows as does opportunity! Best Practice and Research: Clinical Rheumatology, 24 (4). pp. 479-487. ISSN 1521-6942 (doi:10.1016/j.berh.2010.01.004)

Hyslop, E., McInnes, I. B., Woodburn, J., and Turner, D. E. (2010) Foot problems in psoriatic arthritis: high burden and low care provision. Annals of the Rheumatic Diseases, 69 (5). p. 928. ISSN 0003-4967 (doi:10.1136/ard.2009.111971)

Hyslop, E., Woodburn, J., McInnes, I.B., Semple, R., Newcombe, L., Hendry, G., Rafferty, D., De Mits, S., and Turner, D.E. (2010) A reliability study of biomechanical foot function in psoriatic arthritis based on a novel multi-segmented foot model. Gait and Posture, 32 (4). pp. 619-626. ISSN 0966-6362 (doi:10.1016/j.gaitpost.2010.09.004)

Kurowska-Stolarska, M., Hueber, A., Stolarski, B., and McInnes, I. B. (2010) Interleukin-33: a novel mediator with a role in distinct disease pathologies. Journal of Internal Medicine, 269 (1). pp. 29-35. ISSN 0954-6820 (doi:10.1111/j.1365-2796.2010.02316.x)

McInnes, I. B., and O'Dell, J. R. (2010) State-of-the-art: rheumatoid arthritis. Annals of the Rheumatic Diseases, 69 (11). pp. 1898-1906. ISSN 0003-4967 (doi:10.1136/ard.2010.134684)

Millar, N.L., Hueber, A.J., Reilly, J.H., Xu, Y., Fazzi, U.G., Murrell, G.A.C., and McInnes, I.B. (2010) Inflammation is present in early human tendinopathy. American Journal of Sports Medicine, 38 (10). pp. 2085-2091. ISSN 0363-5465 (doi:10.1177/0363546510372613)

Kurowska-Stolarska, Mariola et al. (2009) IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation. Journal of Immunology, 183 (10). pp. 6469-6477. ISSN 0022-1767 (doi:10.4049/jimmunol.0901575)

Lai, Wen-Qi, Irwan, Anastasia Windy, Goh, Hong Heng, Melendez, Alirio J., McInnes, Iain B., and Leung, Bernard P. (2009) Distinct Roles of Sphingosine Kinase 1 and 2 in Murine Collagen-Induced Arthritis. Journal of Immunology, 183 (3). pp. 2097-2103. ISSN 0022-1767 (doi:10.4049/jimmunol.0804376)

Asquith, Darren L., Miller, Ashley M., McInnes, Iain B. , and Liew, Foo Y. (2009) Animal models of rheumatoid arthritis. European Journal of Immunology, 39 (8). pp. 2040-2044. ISSN 0014-2980 (doi:10.1002/eji.200939578 )

McKimmie, Clive S. et al. (2009) A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration. Blood, 113 (18). pp. 4224-4231. ISSN 0006-4971 (doi:10.1182/blood-2008-08-174698 )

Lemos, Henrique P. et al. (2009) Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ  production. Proceedings of the National Academy of Sciences of the United States of America, 106 (14). pp. 5954-5959. ISSN 0027-8424 (doi:10.1073/pnas.0812782106)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182 (2). pp. 963-968. ISSN 0022-1767

Asquith, D, Miller, AM, Hueber, AJ, McKinnon, HJ, Sattar, NA, Graham, GJ, and McInnes, Iain (2009) Liver X Receptor Agonism Promotes Articular Inflammation in Murine Collagen-Induced Arthritis. Arthritis and Rheumatism, 60 (9). pp. 2655-2665. ISSN 0004-3591 (doi:10.1002/art.24717 )

Asquith, D.L., Miller, A.L., McInnes, I.B., and Liew, F.Y. (2009) Autoimmune disease: rheumatoid arthritis. Animal models of rheumatoid arthritis. European Journal of Immunology, 39 . pp. 1991-2058. ISSN 0014-2980

Conigliaro, P, Priori, R, Bombardieri, M, Alessandri, C, Barone, F, Pitzalis, C, McInnes, I, and Valesini, G (2009) Lymph node IL-18 expression in adult-onset Still's disease. Annals of the Rheumatic Diseases, 68 (3). pp. 442-443. ISSN 0003-4967

Gabay, C, and McInnes, I (2009) The biological and clinical importance of the 'new generation' cytokines in rheumatic diseases. Arthritis Research and Therapy, 11 (3).

Hueber, AJ, and McInnes, I (2009) Is spleen tyrosine kinase inhibition an effective therapy for patients with RA? Nature Clinical Practice Rheumatology, 5 (3). pp. 130-131.

Hueber, AJ, Stevenson, RD, Stokes, RJ, Graham, D, Garside, P, and McInnes, I (2009) Imaging inflammation in real time-future of nanoparticles. Autoimmunity, 42 (4). pp. 368-372.

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155 (1). pp. 107-116. ISSN 0009-9104

McInnes, I (2009) Does practice mirror the evidence base in the treatment of rheumatoid arthritis? Clinical Rheumatology, 28 (8). pp. 961-970.

McKellar, GE, McCarey, DW, Sattar, NA, and McInnes, I (2009) Role for TNF in atherosclerosis? Lessons from autoimmune disease. Nature Reviews Cardiology, 6 (6). pp. 410-417.

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68 (6). pp. 1059-1066. ISSN 0003-4967 (doi:10.1136/ard.2008.089300)

Patel, M, McInnes, I, and Graham, G (2009) Atypical Chemokine Receptors in Inflammatory Disease. Current Molecular Medicine, 9 (1). pp. 86-93. ISSN 1566-5240

Yuan, M, Jordan, F, McInnes, I, Harnett, M, and Norman, JE (2009) Leukocytes are primed in peripheral blood for activation during term and preterm labour. Molecular Human Reproduction, 15 (11). pp. 713-724. ISSN 1360-9947 (doi:10.1093/molehr/gap054)

Lai, Wen-Qi, Irwan, Anastasia Windy, Goh, Hong Heng, Howe, Hwee Siew, Yu, David T., Valle-Onate, Rafael, McInnes, Iain B., Melendez, Alirio J., and Leung, Bernard P. (2008) Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis. Journal of Immunology, 181 (11). pp. 8010-8017. ISSN 0022-1767

Niedbala, W., Cai, B., Wei, X., Patakas, A., Leung, B. P., McInnes, I., and Liew, F. Y (2008) Interleukin 27 attenuates collagen-induced arthritis. Annals of the Rheumatic Diseases, 67 (10). pp. 1474-1479. ISSN 0003-4967 (doi:10.1136/ard.2007.083360)

McKimmie, Clive S. et al. (2008) Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. Journal of Immunology, 181 (5). pp. 3353-3363. ISSN 0022-1767

Xu, Damo et al. (2008) IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proceedings of the National Academy of Sciences of the United States of America, 105 (31). pp. 10913-10918. ISSN 0027-8424 (doi:10.1073/pnas.0801898105)

Grespan, Renata, Fukada, Sandra Y., Lemos, Henrique P., Vieira, Silvio M., Napimoga, Marcelo H., Teixeira, Mauro M., Fraser, Alasdair R. , Liew, Foo Y., McInnes, Iain B. , and Cunha, Fernando Q. (2008) CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis. Arthritis and Rheumatism, 58 (7). pp. 2030-2040. ISSN 0004-3591 (doi:10.1002/art.23597)

Culshaw, S.E., Millington, O.R., Brewer, J.M., and McInnes, I. (2008) Murine neutrophils present class II restricted antigen. Immunology Letters, 118 (1). pp. 49-54. ISSN 0165-2478 (doi:10.1016/j.imlet.2008.02.008)

Miller, Ashley M., Xu, Damo, Asquith, Darren L., Denby, Laura, Li, Yubin, Sattar, Naveed, Baker, Andrew H., McInnes, Iain B., and Liew, Foo Y. (2008) IL-33 reduces the development of atherosclerosis. Journal of Experimental Medicine, 205 (2). pp. 339-346. ISSN 0022-1007 (doi:10.1084/jem.20071868 )

Brennan, FM, and McInnes, I (2008) Evidence that cytokines play a role in rheumatoid arthritis. Journal of Clinical Investigation, 118 (11). pp. 3537-3545.

Harnett, M et al. (2008) The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis. Annals of the Rheumatic Diseases, 67 (4). pp. 518-523. ISSN 0003-4967 (doi:10.1136/ard.2007.073502)

Hothersall, EJ et al. (2008) Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax, 63 (12). pp. 1070-1075. ISSN 0040-6376 (doi:10.1136/thx.2008.100198)

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151 (1). pp. 114-122. ISSN 0009-9104

Wong, S., Macrae, V.E., Gracie, J.A., McInnes, I., Galea, P., Gardner-Medwin, J., and Ahmed, S.F. (2008) Inflammatory cytokines in juvenile idiopathic arthritis: Effects on physical growth and the insulin-like-growth factor axis. Growth Hormone and IGF Research, 18 (5). pp. 369-378. ISSN 1096-6374 (doi:10.1016/j.ghir.2008.01.006 )

Verri, Waldiceu A., Cunha, Thiago M., Ferreira, Sérgio H., Wei, Xiaoqing , Leung, Bernard P., Fraser, Alasdair, McInnes, Iain B., Liew, Foo Y., and Cunha, Fernando Q. (2007) IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. European Journal of Immunology, 37 (12). pp. 3373-3380. ISSN 0014-2980 (doi:10.1002/eji.200737488)

Cai, Beilei, Hueber, Axel J., Leung, Bernard P., Liew, Foo Y., McInnes, Iain B., Niedbala, Wanda, and Wei, Xiao-qing (2007) IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. European Journal of Immunology, 37 (11). pp. 3021-3029. ISSN 0014-2980 (doi:10.1002/eji.200737810)

Komai-Koma, Mousa, Li, Yubin , Liew, Foo Y., McInnes, Iain B., McKenzie, Andrew N. J., and Xu, Damo (2007) IL-33 is a chemoattractant for human Th2 cells. European Journal of Immunology, 37 (10). pp. 2779-2786. ISSN 0014-2980 (doi:10.1002/eji.200737547)

Asquith, DL, and McInnes, IB (2007) Emerging cytokine targets in rheumatoid arthritis. Current Opinion in Rheumatology, 19 . pp. 246-251.

Boyle, D et al. (2007) Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: Standardization and consistency across centers. Journal of Rheumatology, 34 . pp. 620-622.

Capell, HA et al. (2007) Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to sulfasalazine: results from the double-blind placebo-controlled MASCOT study. Annals of the Rheumatic Diseases, 66 . pp. 235-241. ISSN 0003-4967 (doi:10.1136/ard.2006.057133)

Dunning, L, Elias-Jones, I, Ferrell, WR, Gracie, JA, Hembrough, T, Kelso, EB, Lockhart, JC, and McInnes, IB (2007) Expression and proinflammatory role of proteinase-activated receptor 2 in rheumatoid synovium - Ex vivo studies using a novel proteinase-activated receptor 2 antagonist. Arthritis and Rheumatism, 56 . pp. 765-771. ISSN 0004-3591 (doi:10.1002/art.22423)

Macrae, VE, Wong, SC, Smith, W, Gracie, A, McInnes, I, Galea, P, Gardner-Medwin, J, Farquharson, C, Ahmed, SF, and Ahmed, SF (2007) Cytokine profiling and in vitro studies of murine bone growth using biological fluids from children with juvenile idiopathic arthritis. Clinical Endocrinology, 67 . pp. 442-448. (doi:10.1111/j.1365-2265.2007.02908.x)

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115 (11). E326-E328.

McInnes, IB, and Schett, G (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nature Reviews Immunology, 7 . pp. 429-442. (doi:10.1038/nri2094)

Sattar, N, Crompton, P, Cherry, L, Kane, D, Lowe, G, and McInnes, IB (2007) Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis - A double-blind, placebo-controlled study. Arthritis and Rheumatism, 56 . pp. 831-839. ISSN 0004-3591 (doi:10.1002/art.22447)

Anderson, EJR, McGrath, MA, McInnes, IB, and Thalhamer, T (2006) Interleukin-12 to interleukin 'infinity': the rationale for future therapeutic cytokine targeting. Springer Seminars in Immunopathology, 27 . pp. 425-442. (doi:10.1007/s00281-006-0011-x)

Baeten, D, Bresnihan, B, De, KF, De, RL, Fitzgerald, O, Kruithof, E, McInnes, I, Tak, PP, Vandooren, B, and Veys, EM (2006) Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis. Arthritis and Rheumatism, 54 . pp. 1795-1804. ISSN 0004-3591 (doi:10.1002/art.21914)

Baeten, D, Bresnihan, B, Fitzgerald, O, McInnes, IB, Smith, MD, Tak, PP, Ulfgren, AK, and Veale, D (2006) Standardisation of synovial tissue infiltrate analysis: how far have we come? how much further do we need to go? Annals of the Rheumatic Diseases, 65 . pp. 93-100. ISSN 0003-4967 (doi:10.1136/ard.2005.036905)

Connell, L., and McInnes, I.B. (2006) New cytokine targets in inflammatory rheumatic diseases. Best Practice and Research: Clinical Rheumatology, 20 . pp. 865-878. ISSN 1521-6942 (doi:10.1016/j.berh.2006.05.011)

Fitzgerald, O., and McInnes, I. (2006) Spondyloarthropathy: disease at the crossroads of immunity. Best Practice and Research: Clinical Rheumatology, 20 . pp. 949-967. ISSN 1521-6942 (doi:10.1016/j.berh.2006.06.010)

Alvaro, J et al. (2005) A multicentre, randomised, double blind, placebo controlled phase II study of subcutaneous interferon beta-1a in the treatment of patients with active rheumatoid arthritis. Annals of the Rheumatic Diseases, 64 . pp. 64-69. ISSN 0003-4967 (doi:10.1136/ard.2003.020347)

Baeten, D et al. (2005) Synovial tissue analysis in clinical trials. Journal of Rheumatology, 32 . pp. 2481-2484.

Baeten, D, Bresnihan, B, Gerlag, DM, Haringman, JJ, Kraan, MC, McInnes, IB, Smeets, TJM, Tak, PP, and Zwinderman, AH (2005) Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 64 . pp. 834-838. ISSN 0003-4967 (doi:10.1136/ard.2004.029751)

Baslund, B et al. (2005) Targeting interleukin-15 in patients with rheumatoid arthritis - A proof-of-concept study. Arthritis and Rheumatism, 52 . pp. 2686-2692. ISSN 0004-3591 (doi:10.1002/art.21249)

Blackbourn, DJ, Gracie, JA, McInnes, IB, and Rezaee, SAR (2005) Inhibition of neutrophil function by the Kaposi's sarcoma-associated herpesvirus vOX2 protein. AIDS, 19 . pp. 1907-1910.

Chandler, D, Griffiths, CEM, Helliwell, P, Kyle, S, Lewis, J, McHugh, N, McInnes, I, Oliver, S, and Symmons, D (2005) Guideline for anti-TNF-alpha therapy in psoriatic arthritis. Rheumatology, 44 . pp. 390-397. (doi:10.1093/rheumatology/keh514)

Choo-Kang, BSW, Hutchison, S, Nickdel, MB, Bundick, RV, Leishman, AJ, Brewer, JM, McInnes, IB, and Garside, P (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26 . pp. 518-522. (doi:10.1016/j.it.2005.07.007)

Culshaw, S, Leung, BP, Gracie, JA, Campbell, CC, Thomson, D, Gemmell, C, Liew, FY, and McInnes, IB (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35 . pp. 1438-1444. (doi:10.1002/ejui.200425661)

Gracie, JA et al. (2005) Disease association of two distinct interleukin-18 promoter polymorphisms in Caucasian rheumatoid arthritis patients. Genes and Immunity, 6 . pp. 211-216. (doi:10.1038/sj.gene.6364183)

Gracie, JA, Liew, FY, and McInnes, IB (2005) Interleukin-18: A therapeutic target in rheumatoid arthritis? Commentary. Arthritis Research and Therapy, 7 . pp. 38-41.

Kane, D, Lockhart, JC, Balint, PV, Mann, C, Ferrell, WR, and McInnes, I (2005) Protective effect of sensory denervation in inflammatory arthritis (evidence of regulatory neuroimmune pathways in the arthritic joint). Annals of the Rheumatic Diseases, 64 (2). pp. 325-327. ISSN 0003-4967

Liew, FY, and McInnes, I (2005) A fork in the pathway to inflammation and arthritis. Nature Medicine, 11 (6). pp. 601-602.

Liew, FY, and McInnes, IB (2005) Cytokine networks - towards new therapies for rheumatoid arthritis. Nature Clinical Practice Rheumatology, 1 . pp. 31-39. (doi:10.1038/ncprheum0020)

McInnes, I (2005) Rheumatoid arthritis: of therapies and strategies. Current Opinion in Rheumatology, 17 (3). pp. 271-273.

McInnes, IB, and Sattar, N (2005) Vascular comorbidity in rheumatoid arthritis: potential mechanisms and solutions. Current Opinion in Rheumatology, 17 . pp. 286-292.

McInnes, I.B., and Gracie, J.A. (2004) Targeting cytokines beyond tumor necrosis factor-alpha and interleukin-1 in rheumatoid arthritis. Current Rheumatology Reports, 6 . pp. 336-342. ISSN 1523-3774

McInnes, I.B., and Gracie, J.A. (2004) Interleukin-15: a new cytokine target for the treatment of inflammatory diseases. Current Opinion in Pharmacology, 4 (4). pp. 392-397. ISSN 1471-4892 (doi:10.1016/j.coph.2004.04.003)

Leung, B.P., Xu, D., Culshaw, S., McInnes, I.B., and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173 (1). pp. 145-150. ISSN 0022-1767

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I.B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173 (1). pp. 151-156. ISSN 0022-1767

Harnett, W., McInnes, I.B., and Harnett, M.M. (2004) ES-62, a filarial nematode-derived immunomodulator with anti-inflammatory potential. Immunology Letters, 94 (1-2). pp. 27-33. ISSN 0165-2478 (doi:10.1016/j.imlet.2004.04.008)

McCarey, D.W., McInnes, I.B., Madhok, R., Hampson, R., Scherbakov, O., Ford, I., Capell, H., and Sattar, N. (2004) Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial. Lancet, 363 (9426). pp. 2015-2021. ISSN 0140-6736 (doi:10.1016/S0140-6736(04)16449-0)

McKay, A., Leung, B.P., McInnes, I.B., Thomson, N.C., and Liew, F.Y. (2004) A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. Journal of Immunology, 172 (5). pp. 2903-2908. ISSN 0022-1767

Wilson, R., Moor, J., Jenkins, C., Miller, H., Walker, J.J., McLean, M.A., Norman, J., and McInnes, I.B. (2004) Abnormal first trimester serum interleukin 18 levels are associated with a poor outcome in women with a history of recurrent miscarriage. American Journal of Reproductive Immunology, 51 (2). pp. 156-159. ISSN 1046-7408 (doi:10.1046/j.8755-8920.2003.00126.x)

Alessandri, C, Barone, F, Blades, MC, Bombardieri, M, Conigliaro, P, McInnes, IB, Pittoni, V, Pitzalis, C, Priori, R, and Valesini, G (2004) Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjogren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Research and Therapy, 6 . R447-R456. (doi:10.1186/ar1209)

Bombardieri, M., Barone, F., Pittoni, P., Alessandri, C., Conigliaro, P., Blades, M.C., Priori, R., McInnes, I.B., Valesini, G., and Pitzalis, C. (2004) Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Research and Therapy, 6 . R447-R456. ISSN 1478-6362 (doi:10.1186/ar1209)

Capell, H, Madhok, R, McCarey, D, McInnes, I, and Sattar, N (2004) Statins and rheumatoid arthritis - Reply. Lancet, 364 (9448). p. 1855.

Harnett, W., Harnett, M.M., Leung, B.P., Gracie, J., and McInnes, I.B. (2004) The anti-inflammatory potential of the filarial nematode secreted product, ES-62. Current Topics in Medicinal Chemistry, 4 (5). pp. 553-559. ISSN 1568-0266 (doi:10.2174/1568026043451212)

Sattar, N., McCarey, D.W., Capell, H., and McInnes, I.B. (2003) Explaining how "high-grade" systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation, 108 (24). pp. 2957-2963. ISSN 1524-4539 (doi:10.1161/01.CIR.0000099844.31524.05)

McInnes, I.B., Gracie, J.A., Harnett, M., Harnett, W., and Liew, F.Y. (2003) New strategies to control inflammatory synovitis: interleukin 15 and beyond. Annals of the Rheumatic Diseases, 62 (2). pp. 51-54. ISSN 0003-4967 (doi:10.1136/ard.62.suppl_2.ii51)

McInnes, I.B., Leung, B.P., Harnett, M., Gracie, J.A., Liew, F., and Harnett, W. (2003) A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62. Journal of Immunology, 171 (4). pp. 2127-2133. ISSN 0022-1767

Wilson, R., Moore, J., Jenkins, C., Miller, H., Maclean, M.A., McInnes, I.B., and Walker, J.J. (2003) Abnormal IL-2 receptor levels in non-pregnant women with a history of recurrent miscarriage. Human Reproduction, 18 (7). pp. 1529-1530. ISSN 0268-1161 (doi:10.1093/humrep/deg287)

Gracie, J.A., Robertson, S.E., and McInnes, I.B. (2003) Interleukin-18. Journal of Leukocyte Biology, 73 (2). pp. 213-224. ISSN 0741-5400 (doi:10.1189/jlb.0602313)

Campbell, C et al. (2003) A novel anti-inflammatory role for simvastatin in inflammatory arthritis. Journal of Immunology, 170 . pp. 1524-1530.

Gracie, JA, Komai-Koma, M, Liew, FY, McInnes, IB, Thomson, N, Wei, XQ, and Xu, DM (2003) Chemoattraction of human T cells by IL-18. Journal of Immunology, 170 . pp. 1084-1090.

McInnes, I.B. (2003) Leukotrienes, mast cells, and T cells. Arthritis Research and Therapy, 5 (6). pp. 288-289. ISSN 1478-6362 (doi:10.1186/ar1017)

Guillen, C, McInnes, I.B., Vaughan, D.M., Kommajosyula, S., Van Berkel, P.H.C,, Leung, B.P., Aguila, A., and Brock, J.H. (2002) Enhanced Th1 response to Staphylococcus aureas infection in human lactoferrin-transgenic mice. Journal of Immunology, 168 (8). pp. 3950-3957. ISSN 0022-1767

Balint, PV, Kane, D, Hunter, J, McInnes, IB, Field, M, and Sturrock, RD (2002) Ultrasound guided versus conventional joint and soft tissue fluid aspiration in rheumatology practice: A pilot study. Journal of Rheumatology, 29 . pp. 2209-2213.

Balint, PV, Kane, D, Wilson, H, McInnes, IB, and Sturrock, RD (2002) Ultrasonography of entheseal insertions in the lower limb in spondyloarthropathy. Annals of the Rheumatic Diseases, 61 . pp. 905-910. ISSN 0003-4967

Boumpas, DT, Ikeuchi, H, Kaneko, Y, Kuroiwa, T, McInnes, IB, Nojima, Y, Ota, F, Tanaka, T, Tsukada, Y, and Ueki, K (2002) Human platelets stimulate mesangial cells to produce monocyte chemoattractant protein-1 via the CD40/CD40 ligand pathway and may amplify glomerular injury. Journal of the American Society of Nephrology, 13 . pp. 2488-2496. (doi:10.1097/01.ASN.0000029588.07166.20)

Gracie, JA, Leung, BP, and McInnes, IB (2002) Novel pathways that regulate tumor necrosis factor-alpha production in rheumatoid arthritis. Current Opinion in Rheumatology, 14 . pp. 270-275.

Leung, BP, Conacher, M, Hunter, D, McInnes, IB, Liew, FY, and Brewer, JM (2002) A novel dendritic cell-induced model of erosive inflammatory arthritis: Distinct roles for dendritic cells in T cell activation and induction of local inflammation. Journal of Immunology, 169 . pp. 7071-7077.

Liew, FY, and McInnes, IB (2002) Role of interleukin 15 and interleukin 18 in inflammatory response. Annals of the Rheumatic Diseases, 61 . pp. 100-102. ISSN 0003-4967

Liew, FY, and McInnes, IB (2002) The role of innate mediators in inflammatory response. Molecular Immunology, 38 . pp. 887-890.

Arthur, HML, Leung, BP, Liew, FY, McInnes, IB, and Wei, XQ (2001) Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. Journal of Immunology, 166 . pp. 517-521.

Boumpas, DT et al. (2001) IL-10 improves skin disease and modulates endothelial activation and leukocyte effector function in patients with psoriatic arthritis. Journal of Immunology, 167 . pp. 4075-4082.

Campbell, C, Canetti, CA, Culshaw, S, Cunha, F, Gracie, JA, Hunter, D, Leung, BP, Liew, FY, and McInnes, IB (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167 . pp. 2879-2886.

Capell, H, Hamilton, J, Madhok, R, Mcinnes, I, and Wilson, H (2001) The hip or not. Journal of Rheumatology, 28 (6). pp. 1398-1400.

Capell, HA, Hamilton, J, Hunter, JA, Madhok, R, McInnes, I, Porter, D, and Thomson, EA (2001) Comparative study of intramuscular gold and methotrexate in a rheumatoid arthritis population from a socially deprived area. Annals of the Rheumatic Diseases, 60 (6). pp. 566-572. ISSN 0003-4967

Capell, HA, Hamilton, JD, Madhok, R, McInnes, I, and Wilson, HE (2001) TNF alpha blockade in rheumatoid arthritis - Time for caution or enthusiasm? Scottish Medical Journal, 46 (3). pp. 67-70.

Esfandiari, E, McInnes, IB, Lindop, G, Huang, FP, Field, M, Komai-Koma, M, Wei, XQ, and Liew, FY (2001) A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. Journal of Immunology, 167 . pp. 5338-5347.

Gao, BM, Gracie, JA, Guan, H, Leung, BP, Liew, FY, McInnes, IB, Niedbala, W, Orchardson, M, Paterson, GK, and Wei, XQ (2001) The sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo. Journal of Immunology, 167 . pp. 277-282.

McCarey, DW, McInnes, I, and Sattar, N (2001) The antiinflammatory effects of statins. New England Journal of Medicine, 345 (16). pp. 1209-1210. ISSN 0028-4793

McInnes, IB (2001) Rheumatoid arthritis - From bench to bedside. Rheumatic Disease Clinics of North America, 27 . pp. 373-387.

Leung, BP, Liew, FY, and McInnes, IB (2000) Cell-cell interactions in synovitis - Interactions between T lymphocytes and synovial cells. Arthritis Research, 2 (5). pp. 374-378.

Conference Proceedings

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, 07-08 June 2010, Manchester, UK.

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, 02-04 Apr 2009, Oxford, Uk.

Dever, G., Rodolico , G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, 29 Apr - 1 May 2009, Washington DC, USA.

This list was generated on Fri Jul 25 15:01:35 2014 BST.