Professor Iain Mcinnes

  • Muirhead Chair of Medicine, Director of Institute and Arthritis Research UK Professor of Rheumatology (Immunology)
  • Muirhead Chair of Medicine & Director of Institute (School of Medicine)

telephone: 01413308412
email: Iain.McInnes@glasgow.ac.uk

Personal assistants:
Miss Claire Grant
telephone: 0141 3308657
email: Claire.Grant.2@glasgow.ac.uk

Mrs Helen Bailey
telephone: 01413308411
email: Helen.Bailey@glasgow.ac.uk

Research interests

Professor McInnes has a major interest in the biology of inflammatory synovitis in rheumatoid arthritis, psoriatic arthritis and septic arthritis. He operates a translational science programme in which state of the art cellular and molecular biology techniques area applied to elucidate the mechanisms underlying the perpetuation of synovial inflammation. In parallel they have an extensive clinical trials facility in which they perform studies of novel biologic agents in inflammatory arthritis.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Enabling Stratified Medicine in Early Rheumatoid Arthritis - predicting methotrexate (MTX) response and toxicity using an integrated polyomic approach (PROMISERA)
    Scottish Funding Council
    2014 - 2016
     
  • Arthritis Research UK Chair in Rheumatology - Meston Bequest
    Arthritis Research UK
    2014 - 2021
     
  • Developing USP7 as a therapeutic target in RA
    Arthritis Research UK
    2014 - 2015
     
  • Research relating to sequences, cells, proteins, and/or constructs
    Compugen Ltd
    2014 - 2015
     
  • In Situ Nanoparticle Assemblies for Healthcare Diagnostics and Therapy
    Engineering & Physical Sciences Research Council
    2014 - 2018
     
  • Tendon therapeutic POC ('TenoMIR')
    Scottish Enterprise
    2014 - 2016
     
  • MAximising Therapeutic Utility for Rheumatoid Arthritis using genetic and genomic tissue responses to stratify medicines (MATURA Consortium)
    Medical Research Council
    2014 - 2016
     
  • MICA: Targeting the RA synovial fibroblast via cyclin dependent kinase inhibition - a phase IIa study
    Medical Research Council
    2014 - 2017
     
  • Synaptopathy in the human brain: studies of postsynaptic proteins in normal and pathological human brains
    Medical Research Council
    2014 - 2017
     
  • Kidney cell-derived exosomes: inter-cellular messengers and vehicles for drug delivery (SCP3 Fellowship)
    Medical Research Council
    2014 - 2017
     
  • Tendon therapeutic POC
    Scottish Enterprise
    2014 - 2014
     
  • The use of polyomic analyses to direct biologic therapy in biologic-naive people with Rheumatoid Arthritis
    Scottish Executive Health Department
    2013 - 2015
     
  • Rheumatoid Arthritis Centre of Excellence (RACE - Towards a Cure)
    Arthritis Research UK
    2013 - 2018
     
  • Comparing the immunophenotype of common inflammatory diseases to understand their pathogenesis.
    Scottish Executive Health Department
    2013 - 2015
     
  • The role of microRNA 29 in tendon disease
    Wellcome Trust
    2013 - 2016
     
  • Urine proteomics as biomarker for inflammatory arthritis
    Pfizer Global Research and Development
    2013 - 2014
     
  • Sessional CRF Support
    NHS Greater Glasgow and CLyde
    2013 - 2014
     
  • Fine-Tuning of Endogenous tendon cells to matrix stiffness and type: The key to optimising repair?
    Horserace Betting Levy Board
    2013 - 2015
     
  • Defining the Role of Cell Migration in the Initiation and Regulation of Pathogenesis in Inflammatory Arthritis
    Arthritis Research UK
    2013 - 2018
     
  • Lessening the burden of osteoarthritis: elucidating the pathogenic role of the PAR-2 Pathway.
    Arthritis Research UK
    2013 - 2018
     
  • EUROTEAM: Towards Early diagnosis and biomarker validation in Arthritis Management
    European Commission
    2012 - 2016
     
  • ARUK Experimental Arthritis Treatment Centre
    Arthritis Research UK
    2012 - 2015
     
  • OSTEOIMMUNE: Unrevealing the Interactions between the Immune System and Bone
    European Commission
    2012 - 2016
     
  • Experimental Arthritis Treatment Centre
    NHS Greater Glasgow and Clyde
    2012 - 2017
     
  • Clinical Research Fellowships
    NHS Greater Glasgow & Clyde
    2012 - 2014
     
  • RAPID: Rheumatoid arthritis and periodonteal inflammatory disease
    European Commission
    2012 - 2016
     
  • An Immunological Toolkit for Clinical Application
    Medical Research Council
    2012 - 2016
     
  • The FLEXCELL FX-5000T Tension System; reintroducing cyclical mechanical strain to cell culture systems
    Arthritis Research UK
    2012 - 2013
     
  • Dendritic Cells in Ankylosing Spondylitis
    Arthritis Research UK
    2011 - 2013
     
  • Leucocyte expression of the D6 chemokine decoy receptor in the pathogenesis of rheumatoid arthritis
    Arthritis Research UK
    2011 - 2013
     
  • SAHSC Industry Support Programme
    East Scotland European Partnership
    2011 - 2014
     
  • SAHSC Industry Support Programme
    University of Glasgow
    2011 - 2014
     
  • Assessing the value and function of D6 as a novel prognostic marker of inflammatory diseases
    Scottish Executive Health Department
    2011 - 2013
     
  • BTCure
    European Commission
    2011 - 2016
     
  • Scottish Clinical Pharmacology and Pathology Programme (SCP3)
    MRC
    2011 - 2016
     
  • Scottish Clinical Pharmacology and Pathology Programme (SCP3) - Fellowship 2011
    Medical Research Council
    2011 - 2016
     
  • The role of DNA methylation in resistance to sunitinib in renal cell cancer (SCP3 Fellowships 2012)
    Medical Research Council
    2011 - 2016
     
  • Phagocyte-fungus interactions in health and disease (SCP3 Fellowships 2012)
    Medical Research Council
    2011 - 2016
     
  • Scottish Clinical Pharmacology and Pathology Programme (SCP3) - Fellowship 2011
    Medical Research Council
    2011 - 2017
     
  • Gums and Joints
    European Commission
    2010 - 2014
     
  • SERA Project
    Southern General Hospital NHS Trust
    2010 - 2011
     
  • Inhibition of osteoclastogenesis by immunomodulatory complexes
    Medical Research Scotland
    2010 - 2013
     
  • In Vivo Reporting using Nanosystems Chemistry and Optical Spectroscopy
    EPSRC
    2010 - 2011
     
  • PAR2 as a therapeutic target in osteoarthritis
    Arthritis Research UK
    2010 - 2013
     
  • The Roles of Migrating Intestinal Dendritic Cells in HLA-B27-Associated Spondylarthropathy
    Arthritis Research UK
    2010 - 2012
     
  • Investigating the role of T cells in vascular pathology
    British Heart Foundation
    2010 - 2010
     
  • IL-33: a novel cytokine that integrates innate and adaptive immune activation in inflammatory arthritis
    Arthritis Research UK
    2010 - 2013
     
  • MicroRNA in monocytes: its contribution to the pathogenesis of arthritis and cardiovascular co-morbidity
    Arthritis Research UK
    2009 - 2014
     
  • Cardiovascular Risk in Rheumatoid Arthritis
    Vienna Medical Academy
    2009 - 2011
     
  • The role of IL-35 in infection and inflammation
    MRC
    2009 - 2012
     
  • DPFS Resource Request (University of Glasgow)
    MRC
    2009 - 2011
     
  • The chemokine decoy receptor D6 in Rheumatoid Arthritis and Inflammation
    Arthritis Research UK
    2009 - 2012
     
  • Tailoring therapy to individual patient needs - the challenge facing rheumatologists who treat patients with Early RA
    Scottish Executive Health Department
    2009 - 2012
     
  • An immuno-histological and molecular investigation into the association of the chemokine decoy receptor D6 with psoriasis.
    Scottish Executive Health Department
    2009 - 2011
     
  • Exploiting the host-parasite relationship to develop novel safe anti-inflammatory therapies
    Arthritis Research UK
    2009 - 2012
     
  • Dissecting the immunomodulatory role of PAR-2 in arthritis
    Arthritis Research UK
    2009 - 2011
     
  • Masterswitch: Mechanics to Attack Steering Effectors of Rheumatoid Syndromes with Innovated Therapy Choices
    European Commission
    2008 - 2013
     
  • Dissecting the role of the human Th17 cell in chronic inflammation
    British Society of Periodontology
    2008 - 2009
     
  • Do fatty acids upregulate inflammatory gene expression? A proof of concept study
    Tenovus-Scotland
    2008 - 2008
     
  • Toll like receptors and chemokine receptors - 2 interconnected arms of the innate immune response
    MRC
    2008 - 2011
     
  • The ST2 Receptor System in Health and Disease
    Wellcome Trust
    2007 - 2012
     
  • PAR2 in the pathogenesis of osteoarthritis
    Arthritis Research UK
    2007 - 2010
     
  • Evidence of risk for the development of premature cardiovascular disease in juvenile idiopathic arthritis?
    Scottish Executive Health Department
    2007 - 2010
     
  • ARC Integrated Clinical Arthritis Centre Grant (ICAC)
    Arthritis Research UK
    2007 - 2008
     
  • Therapeutic potential of a humanised PAR2 antibody to alleviate chronic joint inflammation
    Scottish Executive Health Department
    2006 - 2009
     
  • Function of the atypical chemokine receptor D6 in inflammation
    Arthritis Research UK
    2006 - 2009
     
  • Dissecting the roles played by Dendritic cells and T lymphocytes in mediating inflammatory arthropathies
    Scottish Executive Health Department
    2005 - 2008
     
  • Investigation into the mechanisms by which progesterone prevents preterm delivery
    Action Medical Research
    2005 - 2007
     
  • Realising the Therapeutic Potential of an Anti-inflammatory recombinant viral protein
    Scottish Enterprise
    2005 - 2007
     
  • ES-62, a parasitic nematode derived novel anti-inflammatory agent with broad therapeutic potential
    Scottish Enterprise
    2005 - 2005
     
  • PAR-2 in the pathogenesis of rheumatoid arthritis
    Arthritis Research UK
    2005 - 2006
     
  • Randomised controlled trial to evaluate the effect of statins on asthma control of patients with chronic asthma
    Asthma-UK
    2005 - 2006
     
  • High Fidelity Phenotyping combined with genomics, proteomics and metabonomics close to the patient
    British Heart Foundation
    2004 - 2008
     
  • Adipocyte lipolysis as a candidate pathway in the pathogenesis of pre-eclampsia
    British Heart Foundation
    2004 - 2008
     
  • Elucidating immune mechanisms in inflammatory arthritis
    The Nuffield Foundation
    2004 - 2013
     
  • The effects and mechanism of action of thymosin beta 4 sulphoxide on pulmonary inflammation
    MRC
    2003 - 2006
     
  • Mechanism of Chronicity and Resolution of Inflammatory Diseases
    Wellcome Trust
    2002 - 2006
     
  • A randomised controlled study of combination therapy in rheumatoid artritis (RA) patients with a suboptimal response to sulphasalazine
    Arthritis Research UK
    1999 - 2005
     

Publications

List by: Type | Date

Jump to: 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000
Number of items: 238.

2015

Siebert, S., Tsoukas, A., Robertson, J., and McInnes, I. (2015) Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases. Pharmacological Reviews, 67(2), pp. 280-309. (doi:10.1124/pr.114.009639) (PMID:25697599)

Kelly, S. et al. (2015) Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients. Annals of the Rheumatic Diseases, 74(3), pp. 611-617. (doi:10.1136/annrheumdis-2013-204603) (PMID:24336336)

Hansell, C. A., MacLellan, L. M., Oldham, R. S., Doonan, J., Chapple, K. J., Anderson, E. J., Linington, C., McInnes, I. B., Nibbs, R. J., and Goodyear, C. S. (2015) The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens. Immunology and Cell Biology, 93(2), pp. 167-176. (doi:10.1038/icb.2014.90)

Moraitis, A. G. et al. (2015) Elevated interleukin-10: a new cause of dyslipidemia leading to severe HDL deficiency. Journal of Clinical Lipidology, 9(1), pp. 81-90. (doi:10.1016/j.jacl.2014.09.014) (PMID:25670364)

Platt, A. M., Benson, R. A., McQueenie, R., Butcher, J. P., Braddock, M., Brewer, J. M., McInnes, I. B., and Garside, P. (2015) The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4+ T cell-priming capacity of dendritic cells. Rheumatology, 54(1), pp. 169-177. (doi:10.1093/rheumatology/keu273) (PMID:25065010)

Kristensen, S. L., McInnes, I., and Sattar, N. (2015) Psoriasis, psoriatic arthritis and cardiovascular risk: are we closer to a clinical recommendation? Annals of the Rheumatic Diseases, 74(2), pp. 321-322. (doi:10.1136/annrheumdis-2014-206617)

Miller, N. L., Gilchrist, D., Akbar, M., Reilly, J. H., Kerr, S. C., Campbell, A. L., Murrell, G. A.C., Liew, F. Y., Kurowska-Stolarska, M., and McInnes, I. B. (2015) MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease. Nature Communications, 6, 6774. (doi:10.1038/ncomms7774)

Nanus, D.E., Filer, A.D., Hughes, B., Fisher, B.A., Taylor, P.C., Stewart, P.M., Buckley, C.D., McInnes, I., Cooper, M.S., and Raza, K. (2015) TNF regulates cortisol metabolism in vivo in patients with inflammatory arthritis. Annals of the Rheumatic Diseases, 74(2), pp. 464-469. (doi:10.1136/annrheumdis-2013-203926)

2014

Robertson, J., McInnes, I., and Sattar, N. (2014) Response to ‘Interleukin-6 signal transduction and its role in hepatic lipid metabolic disorders’ by Hassan et al. Cytokine, 70(2), p. 198. (doi:10.1016/j.cyto.2014.05.028)

McInnes, I. B., and Siebert, S. (2014) Psoriatic arthritis - expanding options, exciting times? Acta Reumatologica Portuguesa, 39(4), pp. 294-295.

Kavanaugh, A. et al. (2014) Clinical efficacy, radiographic and safety findings through 5 years of subcutaneous golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of a randomised, placebo-controlled trial (the GO-REVEAL study). Annals of the Rheumatic Diseases, 73(9), pp. 1689-1694. (doi:10.1136/annrheumdis-2013-204902)

Meier, F. M.P., and McInnes, I. B. (2014) Small-molecule therapeutics in rheumatoid arthritis: Scientific rationale, efficacy and safety. Best Practice and Research: Clinical Rheumatology, 28(4), pp. 605-624. (doi:10.1016/j.berh.2014.10.017)

Nurmohamed, M. T., Jamnitski, A., Symmons, D., Peters, M. J. L., Sattar, N., and McInnes, I. (2014) Response to: 'The influence of inflammation in the development of subclinical atherosclerosis in psoriatic arthritis' by Gonzalez-Gay et al. Annals of the Rheumatic Diseases, 73(5), e28. (doi:10.1136/annrheumdis-2014-205174)

Rice, G. I. et al. (2014) Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling. Nature Genetics, 46(5), pp. 503-509. (doi:10.1038/ng.2933)

Patterson, H., Nibbs, R., McInnes, I., and Siebert, S. (2014) Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases. Clinical and Experimental Immunology, 176(1), pp. 1-10. (doi:10.1111/cei.12248)

Dale, J., Purves, D., McConnachie, A., McInnes, I., and Porter, D. (2014) Tightening up? Impact of musculoskeletal ultrasound disease activity assessment on early rheumatoid arthritis patients treated using a treat to target strategy. Arthritis Care and Research, 66(1), pp. 19-26. (doi:10.1002/acr.22218)

Dougados, M. et al. (2014) Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA). Annals of the Rheumatic Diseases, 73(1), pp. 62-68. (doi:10.1136/annrheumdis-2013-204223)

Frleta, M., Siebert, S., and McInnes, I. B. (2014) The interleukin-17 pathway in psoriasis and psoriatic arthritis: disease pathogenesis and possibilities of treatment. Current Rheumatology Reports, 16(414), (doi:10.1007/s11926-014-0414-y)

Kavanaugh, A. et al. (2014) Ustekinumab, an anti-IL-12/23 p40 monoclonal antibody, inhibits radiographic progression in patients with active psoriatic arthritis: results of an integrated analysis of radiographic data from the phase 3, multicentre, randomised, double-blind, placebo-controlled PSUMMIT-1 and PSUMMIT-2 trials. Annals of the Rheumatic Diseases, 73(6), pp. 1000-1006. (doi:10.1136/annrheumdis-2013-204741) (PMID:24553909) (PMCID:PMC4033146)

McInnes, I.B. et al. (2014) Open-label tofacitinib and double-blind atorvastatin in rheumatoid arthritis patients: a randomised study. Annals of the Rheumatic Diseases, 73(1), pp. 124-131. (doi:10.1136/annrheumdis-2012-202442)

McInnes, I.B. et al. (2014) Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Annals of the Rheumatic Diseases, 73(2), pp. 349-356. (doi:10.1136/annrheumdis-2012-202646)

Paul, L., Rafferty, D., Marshall-Mckenna, R., Gill, J.M.R., McInnes, I., Porter, D., and Woodburn, J. (2014) Oxygen cost of walking, physical activity, and sedentary behaviours in rheumatoid arthritis. Scandinavian Journal of Rheumatology, 43(1), pp. 28-34. (doi:10.3109/03009742.2013.802009)

Ritchlin, C. et al. (2014) Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional non-biological and biological anti-tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, double-blind, placebo-controlled, randomised PSUMMIT 2 trial. Annals of the Rheumatic Diseases, 73(6), pp. 990-999. (doi:10.1136/annrheumdis-2013-204655) (PMID:24482301) (PMCID:PMC4033144)

Stalmach, A., Johnsson, H., McInnes, I. B., Husi, H., Klein, J., Dakna, M., Mullen, W., Mischak, H., and Porter, D. (2014) Identification of urinary peptide biomarkers associated with rheumatoid arthritis. PLoS ONE, 9(8), e104625. (doi:10.1371/journal.pone.0104625)

Turner, D. E., Hyslop, E., Barn, R., McInnes, I. B., Steultjens, M. P.M., and Woodburn, J. (2014) Metatarsophalangeal joint pain in psoriatic arthritis: a cross-sectional study. Rheumatology, 53(4), pp. 737-740. (doi:10.1093/rheumatology/ket435)

2013

Lappin, D.F., Apatzidou, D., Quirke, A.M., Oliver-Bell, J., Butcher, J.P., Kinane, D.F., Riggio, M.P., Venables, P., McInnes, I.B., and Culshaw, S. (2013) Influence of periodontal disease, porphyromonas gingivalisand cigarette smoking on systemic anti-citrullinated peptide antibody titres. Journal of Clinical Periodontology, 40(10), pp. 907-915. (doi:10.1111/jcpe.12138)

van den Berg, W.B., and McInnes, I.B. (2013) Th17 cells and IL-17 A—Focus on immunopathogenesis and immunotherapeutics. Seminars in Arthritis and Rheumatism, 43(2), pp. 158-170. (doi:10.1016/j.semarthrit.2013.04.006)

Robertson, J., Peters, M.J., McInnes, I.B., and Sattar, N. (2013) Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm. Nature Reviews Rheumatology, 9(9), pp. 513-523. (doi:10.1038/nrrheum.2013.91)

McInnes, I.B. et al. (2013) Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial. Lancet, 382(9894), pp. 780-789. (doi:10.1016/S0140-6736(13)60594-2)

Schett, G., Elewaut, D., McInnes, I.B., Dayer, J.-M., and Neurath, M.F. (2013) How cytokine networks fuel inflammation: toward a cytokine-based disease taxonomy. Nature Medicine, 19(7), pp. 822-824. (doi:10.1038/nm.3260)

Weir, R. A.P. et al. (2013) Response to letter regarding article, "Galectin-3 and cardiac function in survivors of acute myocardial infarction". Circulation: Heart Failure, 6(4), e58. (doi:10.1161/CIRCHEARTFAILURE.113.000382)

Kapoor, S.R., Filer, A., Fitzpatrick, M.A., Fisher, B.A., Taylor, P.C., Buckley, C.D., McInnes, I.B., Raza, K., and Young, S.P. (2013) Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis. Arthritis and Rheumatism, 65(6), pp. 1448-1456. (doi:10.1002/art.37921)

Weir, R. A.P. et al. (2013) Galectin-3 and cardiac function in survivors of acute myocardial infarction. Circulation: Heart Failure, 6(3), pp. 492-498. (doi:10.1161/CIRCHEARTFAILURE.112.000146)

Villeneuve, E. et al. (2013) Republished: a systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Postgraduate Medical Journal, 89(1050), pp. 231-240. (doi:10.1136/postgradmedj-2011-201063rep)

van der Heijde, D. et al. (2013) EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria. Annals of the Rheumatic Diseases, 72(4), pp. 479-481. (doi:10.1136/annrheumdis-2012-202779)

O'Shea, J.J., Laurence, A., and McInnes, I.B. (2013) Back to the future: oral targeted therapy for RA and other autoimmune diseases. Nature Reviews Rheumatology, 9(3), pp. 173-182. (doi:10.1038/nrrheum.2013.7)

Villeneuve, E. et al. (2013) A systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Annals of the Rheumatic Diseases, 72(1), pp. 13-22. (doi:10.1136/annrheumdis-2011-201063)

Wagner, C.L. et al. (2013) Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab. Annals of the Rheumatic Diseases, 72(1), pp. 83-88. (doi:10.1136/annrheumdis-2012-201697)

Asquith, D.L. et al. (2013) The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release. Annals of the Rheumatic Diseases, 72(12), pp. 2024-2031. (doi:10.1136/annrheumdis-2012-202872)

Coates, L.C. et al. (2013) The 2012 BSR and BHPR guideline for the treatment of psoriatic arthritis with biologics. Rheumatology, 52(10), pp. 1754-1757. (doi:10.1093/rheumatology/ket187)

Crilly, A., Palmer, H.S., Nickdel, M.B., Dunning, L., Lockhart, J.C., Plevin, R., McInnes, I.B., and Ferrell, W.R. (2013) Immunomodulatory role of proteinase-activated receptor-2. Annals of the Rheumatic Diseases, 71(9), pp. 1559-1566. (doi:10.1136/annrheumdis-2011-200869)

Frleta, M., Rainey, A.-A., Gilchrist, D.S., Crawford, L., Baxter, D., Kurowska-Stolarska, M., and McInnes, I.B. (2013) Mir-27b as Biomarker and Regulator of IL-6R Pathway in Resistant Rheumatoid Arthritis Monocyte. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S1035.

Jamnitski, A., Symmons, D., Peters, M.J.L., Sattar, N., McInnes, I., and Nurmohamed, M.T. (2013) Cardiovascular comorbidities in patients with psoriatic arthritis: a systematic review. Annals of the Rheumatic Diseases, 72(2), pp. 211-216. (doi:10.1136/annrheumdis-2011-201194)

Kavanaugh, A. et al. (2013) Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study. Annals of the Rheumatic Diseases, 72(11), pp. 1777-1785. (doi:10.1136/annrheumdis-2012-202035)

McInnes, I.B., Combe, B., and Burmester, G. (2013) Understanding the patient perspective: results of the rheumatoid arthritis: insights, strategies and expectations (RAISE) patient needs survey. Clinical and Experimental Rheumatology, 31(3), pp. 350-7.

Millar, N., Murrell, G.A.C., and McInnes, I. (2013) Alarmins in tendinopathy: unravelling new mechanisms in a common disease. Rheumatology, 52(5), pp. 769-779.

Millar, N.L., Gilchrist, D.S., Kurowska-Stolarska, M., Murrell, G.A.C., and McInnes, I. B. (2013) The Interleukin 33/miR29 Axis Regulates Differential Collagen Production in Tendinopathy. In: EULAR 2013: Annual European Congress of Rheumatology, Madrid, Spain, 12-15 June 2013, p. 140.

Millar, N. L., Gilchrist, D. S., Kurowska-Stolarska, M., Murrell, G. A.C. , and McInnes, I. (2013) The Interleukin 33/miR29 Axis Regulates Differential Collagen Production in Tendinopathy. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S405.

Miller, A. M., Gilchrist, D. S., Nijjar, J., Araldi, E., Ramirez, C. M., Lavery, C. A., Fernández-Hernando, C., McInnes, I. B., and Kurowska-Stolarska, M. (2013) MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice. PLoS ONE, 8(8), e72324. (doi:10.1371/journal.pone.0072324)

Nijjar, J., Tindell, A., McInnes, I.B., and Siebert, S. (2013) Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis. Rheumatology, 52(9), pp. 1556-1562. (doi:10.1093/rheumatology/ket225)

Rainey, A.-A., Gilchrist, D. S., Tange, C. E., Frleta, M., Crawford, L., Baxter, D., McInnes, I. B., and Kurowska-Stolarska, M. (2013) Mir-125a: A novel regulator of IL-6 and TLR driven pathways in RA pathogenesis. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S404.

Steven, R., Crilly, A., Lockhart, J. C., Ferrell, W. R., and McInnes, I. B. (2013) Proteinase-activated receptor-2 modulates human macrophage differentiation andeffector function. Innate Immunity, 19(6), pp. 663-672. (doi:10.1177/1753425913479984)

Tange, C. E., Alivernini, S., Gilchrist, D. S., Crawford, L., Rainey, A.-A., Baxter, D., McInnes, I. B., and Kurowska-Stolarska, M. (2013) Mir-34a in Rheumatoid Arthritis: characterisation of elevated synovial expression and association with treatment resistance. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S403.

2012

Miller, A. M., Xu, D., Asquith, D. L., Denby, L., Li, Y., Sattar, N., Baker, A. H., McInnes, I. B., and Liew, F. Y. (2012) IL-33 reduces the development of atherosclerosis (vol 205, pg 339, 2008). Journal of Experimental Medicine, 209(13), p. 2515. (doi:10.1084/jem.2007186820913c)

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32(11), pp. 2569-2579. (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Miller, A. M. et al. (2012) Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? PLoS ONE, 7(10), e47830. (doi:10.1371/journal.pone.0047830)

Haneklaus, M., Gerlic, M., Kurowska-Stolarska, M., Rainey, A.-A., Pich, D., McInnes, I.B., Hammerschmidt, W., O'Neill, L.A.J., and Masters, S.L. (2012) Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1 production. Journal of Immunology, 189(8), pp. 3795-3799. (doi:10.4049/jimmunol.1200312)

Keystone, E. C., Wang, M. M., Layton, M., Hollis, S., and McInnes, I.B. (2012) Clinical evaluation of the efficacy of the P2X7 purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine. Annals of the Rheumatic Diseases, 71(10), pp. 1630-1635. (doi:10.1136/annrheumdis-2011-143578)

Utriainen, L., Firmin, D., Wright, P., Cerovic, V., Breban, M., McInnes, I., and Milling, S. (2012) Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis. Arthritis and Rheumatism, 64(10), pp. 3199-3209. (doi:10.1002/art.34561)

Weir, R. A.P., Miller, A. M., Petrie, C. J., Clements, S., Steedman, T., Dargie, H. J., Squire, I. B., Ng, L. L., McInnes, I. B., and McMurray, J. J.V. (2012) Interleukin-21 – a biomarker of importance in predicting myocardial function following acute infarction? Cytokine, 60(1), pp. 220-225. (doi:10.1016/j.cyto.2012.06.002)

Singh, M.D. et al. (2012) Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis. American Journal of Pathology, 181(4), pp. 1158-1164. (doi:10.1016/j.ajpath.2012.06.042)

Statache, G., Rainey, A.-A., Masters, S., Balanescu, A., McInnes, I. B., and Kurowska-Stolarska, M. (2012) Regulation of microrna 223 expression in a gouty arthritis. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Washington DC, USA, 9-14 Nov 2012, S811. (doi:10.1002/art.37735)

Tindell, A.G., Kelso, E.B., Ferrell, W.R., Lockhart, J.C., Walsh, D.A., Dunning, L., and McInnes, I.B. (2012) Correlation of protease-activated receptor-2 expression and synovitis in rheumatoid and osteoarthritis. Rheumatology International, 32(10), pp. 3077-3086. (doi:10.1007/s00296-011-2102-9)

Komai-Koma, M. et al. (2012) Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice. Allergy, 67(9), pp. 1118-1126. (doi:10.1111/j.1398-9995.2012.02859.x)

Elmesmari, A., Gilchrist, D., Fraser, A., Brewer, J., McInnes, I., and Kurowska-Stolarska, M. (2012) The role of miR-155 in monocyte migration in Rheumatoid arthritis. In: European Congress of Immunology, Glasgow, UK, 5-8 Sept 2012, pp. 588-589. (doi:10.1111/imm.12002)

Elmesmari, A., Pushparaj, P., Reilly, J., Kerr, S., Kurowska-Stolarska, M., and McInnes, I. (2012) The role of SPHKs and SIPRs in rheumatoid arthritis. In: European Congress of Immunology, Glasgow, UK, 5-8 Sept 2012, p. 260. (doi:10.1111/imm.12002)

Statache, G., Rainey, A., Crawford, L., Masters, S., Balanescu, A., McInnes, I., and Kurowska-Stolarska, M. (2012) Regulation of microRNA 223 expression in a gouty arthritis. In: European Congress of Immunology, Glasgow, UK, 5-8 Sept 2012, p. 227. (doi:10.1111/imm.12002)

Kavanaugh, A. et al. (2012) Golimumab in psoriatic arthritis: one-year clinical efficacy, radiographic, and safety results from a phase III, randomized, placebo-controlled trial. Arthritis and Rheumatism, 64(8), pp. 2504-2517. (doi:10.1002/art.34436)

McInnes, I., Lee, J.S., Thompson, L., Giles, J.T., Bathton, J.M., Salmon, J.E., Beaulieu, A.D., Codding, C.E., Delles, C., and Sattar, N. (2012) The effects of tocilizumab treatment on lipids and inflammatory/prothrombotic markers in patients (pts) with rheumatoid arthritis (RA): data from the randomized, controlled, measure study. European Heart Journal, 33(Sup 1), p. 281. (doi:10.1093/eurheartj/ehs281)

Crilly, A. et al. (2012) PAR2 expression in peripheral blood monocytes of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71(6), pp. 1049-1054. (doi:10.1136/annrheumdis-2011-200703)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119(11), pp. 2545-2551. (doi:10.1182/blood-2011-09-378356)

Baxter, D., McInnes, I.B., and Kurowska-Stolarska, M. (2012) Novel regulatory mechanisms in inflammatory arthritis: a role for microRNA. Immunology and Cell Biology, 90(3), pp. 288-292. (doi:10.1038/icb.2011.114)

Elmesmari, A., Gilchrist, D. S., Fraser, A. D., Vaughan, D., McQueenie, R., Graham, G., Brewer, J., McInnes, I. B., and Kurowska-Stolarska, M. (2012) Microrna-155 regulates chemokines and chemokine receptors in Rheumatoid Arthritis monocyte. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Washington DC, USA, 9-14 Nov 2012, S384. (doi:10.1002/art.37735)

Frleta, M., King, V., Reilly, J.H., Gilchrist, D.S., Tornehave, D., Lundsgaard, D., Miller, A.M., and McInnes, I.B. (2012) Expression of IL-21 receptor in synovial tissue and blood of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71(Sup. 1), A83. (doi:10.1136/annrheumdis-2011-201238.25)

Gossec, L. et al. (2012) European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Annals of the Rheumatic Diseases, 71(1), pp. 4-12. (doi:10.1136/annrheumdis-2011-200350)

Henningsson, L., Jirholt, P., Bogestal, Y.R., Eneljung, T., Adiels, M., Lindholm, C., McInnes, I., Bulfone-Paus, S., Lerner, U.H., and Gjertsson, I. (2012) Interleukin 15 mediates joint destruction in Staphylococcus aureus arthritis. Journal of Infectious Diseases, 206(5), pp. 687-696. (doi:10.1093/infdis/jis295)

Johnsson, H., McInnes, I.B., and Sattar, N. (2012) Cardiovascular and metabolic risks in psoriasis and psoriatic arthritis: pragmatic clinical management based on available evidence. Annals of the Rheumatic Diseases, 71(4), pp. 480-483. (doi:10.1136/annrheumdis-2011-200567)

Kerekes, G., Soltész, P., Nurmohamed, M.T., Gonzalez-Gay, M.A., Turiel, M., Végh, E., Shoenfeld, Y., McInnes, I., and Szekanecz, Z. (2012) Validated methods for assessment of subclinical atherosclerosis in rheumatology. Nature Reviews Rheumatology, 8(4), pp. 224-234. (doi:10.1038/nrrheum.2012.16)

Kurowska-Stolarska, M., Hasoo, M., Gilchrist, D. G., Ruzicska, E., Asquith, D., Welsh, D., Crawford, L., Hirani, N., McInnes, I. B., and McSharry, C. (2012) Microrna-155 protects against pulmonary fibrosis by targeting the transcription regulator LXR alpha. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Washington DC, USA, 9-14 Nov 2012, S386. (doi:10.1002/art.37735)

Lories, R.J., and McInnes, I.B. (2012) Primed for inflammation: enthesis-resident T cells. Nature Medicine, 18(7), pp. 1018-1019. (doi:10.1038/nm.2854)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84(14), pp. 5968-5975. (doi:10.1021/ac3006445)

Millar, N.L., Reilly, J.H., Kerr, S.C., Campbell, A.L., Little, K.J., Leach, W.J., Rooney, B.P., Murrell, G.A.C., and McInnes, I.B. (2012) Hypoxia: a critical regulator of early human tendinopathy. Annals of the Rheumatic Diseases, 71(2), pp. 302-310. (doi:10.1136/ard.2011.154229)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Steinman, L., Merrill, J.T., McInnes, I.B., and Peakman, M. (2012) Optimization of current and future therapy for autoimmune diseases. Nature Medicine, 18(1), pp. 59-65. (doi:10.1038/nm.2625)

Wenink, M.H., Santegoets, K.C.M., Platt, A.M., van den Berg, W.B., van Riel, P.L.C.M., Garside, P., Radstake, T.R.D.J., and McInnes, I.B. (2012) Abatacept modulates proinflammatory macrophage responses upon cytokine-activated T cell and Toll-like receptor ligand stimulation. Annals of the Rheumatic Diseases, 71(1), pp. 80-83. (doi:10.1136/annrheumdis-2011-200348)

Xuzhu, G., Komai-Koma, M., Leung, B.P., Howe, H.S., McSharry, C., McInnes, I.B., and Xu, D. (2012) Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. Annals of the Rheumatic Diseases, 71(1), pp. 129-135. (doi:10.1136/ard.2011.149831)

2011

McInnes, I.B., and Schett, G. (2011) The pathogenesis of rheumatoid arthritis. New England Journal of Medicine, 365(23), pp. 2205-2219. (doi:10.1056/NEJMra1004965)

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! FEBS Letters, 585(23), pp. 2640-3648. (doi:10.1016/j.febslet.2011.04.069)

Wenink, M.H., Santegoets, K.C.M., Butcher, J., van Bon, L., Lamers-Karnebeek, F.G.M., van den Berg, W.B., van Riel, P.L.C.M., McInnes, I.B., and Radstake, T.R.D.J. (2011) Impaired dendritic cell proinflammatory cytokine production in psoriatic arthritis. Arthritis and Rheumatism, 63(11), pp. 3313-3322. (doi:10.1002/art.30577)

Welsh, P. et al. (2011) Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arteriosclerosis, Thrombosis and Vascular Biology, 31(10), pp. 2338-2344. (doi:10.1161/ATVBAHA.111.231795)

Hueber, A. J., Alves-Filho, J. C., Asquith, D. L., Michels, C. , Millar, N. L., Reilly, J. H., Graham, G. J., Liew, F. Y., Miller, A. M., and McInnes, I. B. (2011) IL-33 induces skin inflammation with mast cell and neutrophil activation. European Journal of Immunology, 41(8), pp. 2229-2237. (doi:10.1002/eji.201041360)

Conigliaro, P., Benson, R.A., Patakas, A., Kelly, S.M., Valesini, G., Homdahl, R., Brewer, J.M., McInnes, I.B., and Garside, P. (2011) Characterization of the anti-collagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63(8), pp. 2299-2308. (doi:10.1002/art.30413)

Conigliaro, P., Benson, R. A., Patakas, A., Kelly, S. M., Valesini, G., Holmdahl, R., Brewer, J. M., McInnes, I. B., and Garside, P. (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63(8), pp. 2299-2308. (doi:10.1002/art.30413)

Kurowska-Stolarska, M. et al. (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proceedings of the National Academy of Sciences of the United States of America, 108(27), pp. 11193-11198. (doi:10.1073/pnas.1019536108)

Patakas, A., Platt, A. M., Butcher, J. P., Maffia, P., McInnes, I. B., Brewer, J. M., Garside, P., and Benson, R. A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138(1), pp. 38-46. (doi:10.1016/j.imlet.2011.03.002)

Zaiss, M. M. et al. (2011) IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-α–mediated bone loss. Journal of Immunology, 186(11), pp. 6097-6105. (doi:10.4049/jimmunol.1003487)

Welsh, P. et al. (2011) Vitamin D deficiency is common in patients with RA and linked to disease activity, but circulating levels are unaffected by TNF blockade: results from a prospective cohort study. Annals of the Rheumatic Diseases, 70(6), pp. 1165-1167. (doi:10.1136/ard.2010.137265)

Hansell, C. A. H., Schiering, C., Kinstrie, R., Ford, L., Bordon, Y., McInnes, I. B., Goodyear, C. S., and Nibbs, R. J.B. (2011) Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice. Blood, 117(20), pp. 5413-5424. (doi:10.1182/blood-2010-11-317115)

Krishnadas, R., Mallon, V., McInnes, I., and Cavanagh, J. (2011) Correlates of depression and quality of life in patients with inflammatory arthritides. European Psychiatry, 26, p. 383. (doi:10.1016/S0924-9338(11)72091-0)

Norman, J.E., Yuan, M., Anderson, L., Howie, F., Harold, G., Young, A., Jordan, F., McInnes, I., and Harnett, M.M. (2011) Effect of prolonged in vivo administration of progesterone in pregnancy on myometrial gene expression, peripheral blood leukocyte activation, and circulating steroid hormone levels. Reproductive Sciences, 18(5), pp. 435-446. (doi:10.1177/1933719110395404)

Culshaw, S., McInnes, I. B., and Liew, F. Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38(S11), pp. 106-113. (doi:10.1111/j.1600-051X.2010.01669.x)

Codullo, V. et al. (2011) An investigation of the inflammatory cytokine and chemokine network in systemic sclerosis. Annals of the Rheumatic Diseases, 70(6), pp. 1115-1121. (doi:10.1136/ard.2010.137349 )

Miller, A., and McInnes, I. (2011) Cytokines as therapeutic targets to reduce cardiovascular risk in chronic inflammation. Current Pharmaceutical Design, 17(1), pp. 1-8. (doi:10.2174/138161211795049796)

Alivernini, S. et al. (2011) The role of microRNA-34 and microRNA-22 in dendritic cells and monocyte activation in rheumatoid arthritis. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Chicago, IL USA, 4-9 Nov 2011, S654.

Asquith, D.L., Miller, A.M., Reilly, J.H., Kerr, S., Welsh, P., Sattar, N., and McInnes, I.B. (2011) Simultaneous activation of the liver X receptors (LXR and LXR) drives murine collagen-induced arthritis disease pathology. Annals of the Rheumatic Diseases, 70(12), pp. 2225-2228. (doi:10.1136/ard.2011.152652)

Bombardieri, M., Kam, N.-W., Brentano, F., Choi, K., Filer, A., Kyburz, D., McInnes, I.B., Gay, S., Buckley, C., and Pitzalis, C. (2011) A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells. Annals of the Rheumatic Diseases, 70(10), pp. 1857-1865. (doi:10.1136/ard.2011.150219)

Crilly, A., Robertson, S.E., Reilly, J.H., Gracie, J.A., Lai, W.-Q., Leung, B.P., Life, P.F., and McInnes, I.B. (2011) Phosphodiesterase 4 (PDE4) regulation of proinflammatory cytokine and chemokine release from rheumatoid synovial membrane. Annals of the Rheumatic Diseases, 70(6), pp. 1130-1137. (doi:10.1136/ard.2010.134825)

Laing, S., Hernandez-Santana, A., Sassmannshausen, J., Asquith, D.L., McInnes, I.B., Faulds, K., and Graham, D. (2011) Quantitative Detection of Human Tumor Necrosis Factor α by a Resonance Raman Enzyme-Linked Immunosorbent Assay. Analytical Chemistry, 83(1), pp. 297-302. (doi:10.1021/ac1024039)

MacLellan, L.M., Montgomery, J., Sugiyama, F., Kitson, S.M., Thümmler, K., Silverman, G.J., Beers, S.A., Nibbs, R.J.B., McInnes, I.B., and Goodyear, C.S. (2011) Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice. Arthritis and Rheumatism, 63(12), pp. 3897-3907. (doi:10.1002/art.30629)

Pitman, N., Asquith, D.L., Murphy, G., Liew, F.Y., and McInnes, I.B. (2011) Collagen-induced arthritis is not impaired in mast cell-deficient mice. Annals of the Rheumatic Diseases, 70(6), pp. 1170-1171. (doi:10.1136/ard.2010.134528)

Zwerina, K. et al. (2011) Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance. European Journal of Immunology, 42(2), pp. 413-423. (doi:10.1002/eji.201141871)

van de Sande, M. G. H. et al. (2011) Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials. Annals of the Rheumatic Diseases, 70(3), pp. 423-427. (doi:10.1136/ard.2010.139550)

2010

Miller, A. M., Asquith, D. L., Hueber, A. J., Anderson, L. A., Holmes, W. M., McKenzie, A. N., Xu, D., Sattar, N., McInnes, I. B., and Liew, F. Y. (2010) Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circulation Research, 107(5), pp. 650-658. (doi:10.1161/CIRCRESAHA.110.218867)

Verri, W. A. et al. (2010) IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Annals of the Rheumatic Diseases, 69(9), pp. 1697-1703. (doi:10.1136/ard.2009.122655)

Emery, P., Buch, M.H., Östör, A., Kirkham, B., Taylor, P., Estrach, C., Jenkinson, T., McInnes, I., and Porter, D. (2010) Time for treatment targets in rheumatoid arthritis. British Medical Journal, 341(c4170), p. 267. (doi:10.1136/bmj.c4170)

Platt, A. M., Gibson, V. B., Patakas, A., Benson, R. A., Nadler, S. G., Brewer, J. M., McInnes, I., and Garside, P. (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185(3), pp. 1558-1567. (doi:10.4049/jimmunol.1001311 )

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184(11), pp. 6378-6385. (doi:10.4049/jimmunol.0903951)

Hueber, A. J., Asquith, D. L., Miller, A. M., Reilly, J., Kerr, S., Leipe, J., Melendez Romero, A. J., and McInnes, I. B. (2010) Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium. Journal of Immunology, 184(7), pp. 3336-3340. (doi:10.4049/jimmunol.0903566)

Xu, D. et al. (2010) IL-33 exacerbates autoantibody-induced arthritis. Journal of Immunology, 184(5), pp. 2620-2626. (doi:10.4049/jimmunol.0902685)

Asquith, D. L., Miller, A. M., Hueber, A. J., Liew, F. Y., Sattar, N., and McInnes, I. B. (2010) Apolipoprotein E-deficient mice are resistant to the development of collagen-induced arthritis. Arthritis and Rheumatism, 62(2), pp. 472-477. (doi:10.1002/art.27205)

Liew, F. Y., Pitman, N. I., and McInnes, I. B. (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nature Reviews Immunology, 10(2), pp. 103-110. (doi:10.1038/nri2692)

Weir, R.A.P., Miller, A.M., Murphy, G., Clements, S., Steedman, T., Connell, J., McInnes, I., Dargie, H., and McMurray, J.J. (2010) Serum soluble ST2 a potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction. Journal of the American College of Cardiology, 55(3), pp. 243-250. (doi:10.1016/j.jacc.2009.08.047)

Murphy, G.E.J., Xu, D., Liew, F.Y., and McInnes, I.B. (2010) Role of interleukin 33 in human immunopathology. Annals of the Rheumatic Diseases, 69(Suppl ), pp. 43-47. (doi:10.1136/ard.2009.120113)

Cavanagh, J., Paterson, C., McLean, J., Pimlott, S., McDonald, M., Patterson, J., Wyper, D., and McInnes, I. (2010) Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study. Annals of the Rheumatic Diseases, 69(6), 1251-U367. (doi:10.1136/ard.2009.107912)

Ferrell, W.R., Kelso, E.B., Lockhart, J.C., Plevin, R., and McInnes, I.B. (2010) Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis. Annals of the Rheumatic Diseases, 69(11), pp. 2051-2054. (doi:10.1136/ard.2010.130336)

Fraser, A.R., Perry, M.E., Crilly, A., Reilly, J.H., Hueber, A.J., and McInnes, I.B. (2010) Lipoma arborescens co-existing with psoriatic arthritis releases tumour necrosis factor alpha and matrix metalloproteinase. Annals of the Rheumatic Diseases, 69(4), pp. 776-777. (doi:10.1136/ard.2008.106047)

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, Manchester, UK, 07-08 June 2010, e12. (doi:10.1136/hrt.2010.205781.11)

Hueber, A.J., Asquith, D.L., McInnes, I.B., and Miller, A.M. (2010) Embracing novel cytokines in RA – complexity grows as does opportunity! Best Practice and Research: Clinical Rheumatology, 24(4), pp. 479-487. (doi:10.1016/j.berh.2010.01.004)

Hyslop, E., McInnes, I. B., Woodburn, J., and Turner, D. E. (2010) Foot problems in psoriatic arthritis: high burden and low care provision. Annals of the Rheumatic Diseases, 69(5), p. 928. (doi:10.1136/ard.2009.111971)

Hyslop, E., Woodburn, J., McInnes, I.B., Semple, R., Newcombe, L., Hendry, G., Rafferty, D., De Mits, S., and Turner, D.E. (2010) A reliability study of biomechanical foot function in psoriatic arthritis based on a novel multi-segmented foot model. Gait and Posture, 32(4), pp. 619-626. (doi:10.1016/j.gaitpost.2010.09.004)

Kurowska-Stolarska, M., Hueber, A., Stolarski, B., and McInnes, I. B. (2010) Interleukin-33: a novel mediator with a role in distinct disease pathologies. Journal of Internal Medicine, 269(1), pp. 29-35. (doi:10.1111/j.1365-2796.2010.02316.x)

Kurowska-Stolarska, M., Ballantine, L., Stolarski, B., Hunter, J., Hueber, A., Gracie, J.A., Liew, F. Y., and McInnes, I. B. (2010) miR-155 and miR-34a regulate proinflammatory cytokine production by human monocytes. In: European Workshop for Rheumatology Research, Bamberg, Germany, 4-7 Mar 2010, A30-A30. (doi:10.1136/ard.2010.129619g)

McInnes, I. B., and O'Dell, J. R. (2010) State-of-the-art: rheumatoid arthritis. Annals of the Rheumatic Diseases, 69(11), pp. 1898-1906. (doi:10.1136/ard.2010.134684)

Millar, N.L., Hueber, A.J., Reilly, J.H., Xu, Y., Fazzi, U.G., Murrell, G.A.C., and McInnes, I.B. (2010) Inflammation is present in early human tendinopathy. American Journal of Sports Medicine, 38(10), pp. 2085-2091. (doi:10.1177/0363546510372613)

2009

Kurowska-Stolarska, M. et al. (2009) IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation. Journal of Immunology, 183(10), pp. 6469-6477. (doi:10.4049/jimmunol.0901575)

Lai, W.-Q., Irwan, A. W., Goh, H. H., Melendez, A. J., McInnes, I. B., and Leung, B. P. (2009) Distinct Roles of Sphingosine Kinase 1 and 2 in Murine Collagen-Induced Arthritis. Journal of Immunology, 183(3), pp. 2097-2103. (doi:10.4049/jimmunol.0804376)

Asquith, D. L., Miller, A. M., McInnes, I. B. , and Liew, F. Y. (2009) Animal models of rheumatoid arthritis. European Journal of Immunology, 39(8), pp. 2040-2044. (doi:10.1002/eji.200939578 )

McKimmie, C. S. et al. (2009) A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration. Blood, 113(18), pp. 4224-4231. (doi:10.1182/blood-2008-08-174698 )

Lemos, H. P. et al. (2009) Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ  production. Proceedings of the National Academy of Sciences of the United States of America, 106(14), pp. 5954-5959. (doi:10.1073/pnas.0812782106)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182(2), pp. 963-968.

Asquith, D., Miller, A., Hueber, A., McKinnon, H., Sattar, N., Graham, G., and McInnes, I. (2009) Liver X Receptor Agonism Promotes Articular Inflammation in Murine Collagen-Induced Arthritis. Arthritis and Rheumatism, 60(9), pp. 2655-2665. (doi:10.1002/art.24717 )

Asquith, D.L., Miller, A.L., McInnes, I.B., and Liew, F.Y. (2009) Autoimmune disease: rheumatoid arthritis. Animal models of rheumatoid arthritis. European Journal of Immunology, 39, pp. 1991-2058.

Conigliaro, P., Priori, R., Bombardieri, M., Alessandri, C., Barone, F., Pitzalis, C., McInnes, I., and Valesini, G. (2009) Lymph node IL-18 expression in adult-onset Still's disease. Annals of the Rheumatic Diseases, 68(3), pp. 442-443.

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, Oxford, Uk, 02-04 Apr 2009, (doi:10.1136/hrt.2009.178137i)

Dever, G., Rodolico , G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, Washington DC, USA, 29 Apr - 1 May 2009, e74. (doi:10.1161/ATV.0B013E3181AB66E7)

Gabay, C., and McInnes, I. (2009) The biological and clinical importance of the 'new generation' cytokines in rheumatic diseases. Arthritis Research and Therapy, 11(3),

Hueber, A., and McInnes, I. (2009) Is spleen tyrosine kinase inhibition an effective therapy for patients with RA? Nature Clinical Practice Rheumatology, 5(3), pp. 130-131.

Hueber, A., Stevenson, R., Stokes, R., Graham, D., Garside, P., and McInnes, I. (2009) Imaging inflammation in real time-future of nanoparticles. Autoimmunity, 42(4), pp. 368-372.

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155(1), pp. 107-116.

McInnes, I. (2009) Does practice mirror the evidence base in the treatment of rheumatoid arthritis? Clinical Rheumatology, 28(8), pp. 961-970.

McKellar, G., McCarey, D., Sattar, N., and McInnes, I. (2009) Role for TNF in atherosclerosis? Lessons from autoimmune disease. Nature Reviews Cardiology, 6(6), pp. 410-417.

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68(6), pp. 1059-1066. (doi:10.1136/ard.2008.089300)

Patel, M., McInnes, I., and Graham, G. (2009) Atypical Chemokine Receptors in Inflammatory Disease. Current Molecular Medicine, 9(1), pp. 86-93.

Yuan, M., Jordan, F., McInnes, I., Harnett, M., and Norman, J. (2009) Leukocytes are primed in peripheral blood for activation during term and preterm labour. Molecular Human Reproduction, 15(11), pp. 713-724. (doi:10.1093/molehr/gap054)

2008

Lai, W.-Q., Irwan, A. W., Goh, H. H., Howe, H. S., Yu, D. T., Valle-Onate, R., McInnes, I. B., Melendez, A. J., and Leung, B. P. (2008) Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis. Journal of Immunology, 181(11), pp. 8010-8017.

Niedbala, W., Cai, B., Wei, X., Patakas, A., Leung, B. P., McInnes, I., and Liew, F. Y. (2008) Interleukin 27 attenuates collagen-induced arthritis. Annals of the Rheumatic Diseases, 67(10), pp. 1474-1479. (doi:10.1136/ard.2007.083360)

McKimmie, C. S. et al. (2008) Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. Journal of Immunology, 181(5), pp. 3353-3363.

Kurowska-Stolarska, M. S., Kewin, P., Stolarski, B., Fraser, A., Xu, D., McInnes, I., and Liew, F. Y. (2008) A role of IL-33 in bone turnover. In: 72nd Annual Scientific Meeting of the American College of Rheumatology and the 43rd Annual Scientific Meeting of the Association of Rheumatology Health Professionals, San Francisco CA, USA, 24-29 Oct 2008, S895.

Xu, D. et al. (2008) IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proceedings of the National Academy of Sciences of the United States of America, 105(31), pp. 10913-10918. (doi:10.1073/pnas.0801898105)

Grespan, R., Fukada, S. Y., Lemos, H. P., Vieira, S. M., Napimoga, M. H., Teixeira, M. M., Fraser, A. R. , Liew, F. Y., McInnes, I. B. , and Cunha, F. Q. (2008) CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis. Arthritis and Rheumatism, 58(7), pp. 2030-2040. (doi:10.1002/art.23597)

Culshaw, S.E., Millington, O.R., Brewer, J.M., and McInnes, I. (2008) Murine neutrophils present class II restricted antigen. Immunology Letters, 118(1), pp. 49-54. (doi:10.1016/j.imlet.2008.02.008)

Miller, A. M., Xu, D., Asquith, D. L., Denby, L., Li, Y., Sattar, N., Baker, A. H., McInnes, I. B., and Liew, F. Y. (2008) IL-33 reduces the development of atherosclerosis. Journal of Experimental Medicine, 205(2), pp. 339-346. (doi:10.1084/jem.20071868 )

Brennan, F., and McInnes, I. (2008) Evidence that cytokines play a role in rheumatoid arthritis. Journal of Clinical Investigation, 118(11), pp. 3537-3545.

Harnett, M. et al. (2008) The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis. Annals of the Rheumatic Diseases, 67(4), pp. 518-523. (doi:10.1136/ard.2007.073502)

Hothersall, E. et al. (2008) Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax, 63(12), pp. 1070-1075. (doi:10.1136/thx.2008.100198)

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151(1), pp. 114-122.

Wong, S., Macrae, V.E., Gracie, J.A., McInnes, I., Galea, P., Gardner-Medwin, J., and Ahmed, S.F. (2008) Inflammatory cytokines in juvenile idiopathic arthritis: Effects on physical growth and the insulin-like-growth factor axis. Growth Hormone and IGF Research, 18(5), pp. 369-378. (doi:10.1016/j.ghir.2008.01.006 )

2007

Verri, W. A., Cunha, T. M., Ferreira, S. H., Wei, X. , Leung, B. P., Fraser, A., McInnes, I. B., Liew, F. Y., and Cunha, F. Q. (2007) IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. European Journal of Immunology, 37(12), pp. 3373-3380. (doi:10.1002/eji.200737488)

Cai, B., Hueber, A. J., Leung, B. P., Liew, F. Y., McInnes, I. B., Niedbala, W., and Wei, X.-q. (2007) IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. European Journal of Immunology, 37(11), pp. 3021-3029. (doi:10.1002/eji.200737810)

Komai-Koma, M., Li, Y. , Liew, F. Y., McInnes, I. B., McKenzie, A. N. J., and Xu, D. (2007) IL-33 is a chemoattractant for human Th2 cells. European Journal of Immunology, 37(10), pp. 2779-2786. (doi:10.1002/eji.200737547)

Asquith, D., and McInnes, I. (2007) Emerging cytokine targets in rheumatoid arthritis. Current Opinion in Rheumatology, 19, pp. 246-251.

Boyle, D. et al. (2007) Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: Standardization and consistency across centers. Journal of Rheumatology, 34, pp. 620-622.

Capell, H. et al. (2007) Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to sulfasalazine: results from the double-blind placebo-controlled MASCOT study. Annals of the Rheumatic Diseases, 66, pp. 235-241. (doi:10.1136/ard.2006.057133)

Dunning, L., Elias-Jones, I., Ferrell, W., Gracie, J., Hembrough, T., Kelso, E., Lockhart, J., and McInnes, I. (2007) Expression and proinflammatory role of proteinase-activated receptor 2 in rheumatoid synovium - Ex vivo studies using a novel proteinase-activated receptor 2 antagonist. Arthritis and Rheumatism, 56, pp. 765-771. (doi:10.1002/art.22423)

Macrae, V., Wong, S., Smith, W., Gracie, A., McInnes, I., Galea, P., Gardner-Medwin, J., Farquharson, C., Ahmed, S., and Ahmed, S. (2007) Cytokine profiling and in vitro studies of murine bone growth using biological fluids from children with juvenile idiopathic arthritis. Clinical Endocrinology, 67, pp. 442-448. (doi:10.1111/j.1365-2265.2007.02908.x)

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), E326-E328.

McInnes, I., and Schett, G. (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nature Reviews Immunology, 7, pp. 429-442. (doi:10.1038/nri2094)

Sattar, N., Crompton, P., Cherry, L., Kane, D., Lowe, G., and McInnes, I. (2007) Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis - A double-blind, placebo-controlled study. Arthritis and Rheumatism, 56, pp. 831-839. (doi:10.1002/art.22447)

2006

Anderson, E., McGrath, M., McInnes, I., and Thalhamer, T. (2006) Interleukin-12 to interleukin 'infinity': the rationale for future therapeutic cytokine targeting. Springer Seminars in Immunopathology, 27, pp. 425-442. (doi:10.1007/s00281-006-0011-x)

Baeten, D., Bresnihan, B., De, K., De, R., Fitzgerald, O., Kruithof, E., McInnes, I., Tak, P., Vandooren, B., and Veys, E. (2006) Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis. Arthritis and Rheumatism, 54, pp. 1795-1804. (doi:10.1002/art.21914)

Baeten, D., Bresnihan, B., Fitzgerald, O., McInnes, I., Smith, M., Tak, P., Ulfgren, A., and Veale, D. (2006) Standardisation of synovial tissue infiltrate analysis: how far have we come? how much further do we need to go? Annals of the Rheumatic Diseases, 65, pp. 93-100. (doi:10.1136/ard.2005.036905)

Connell, L., and McInnes, I.B. (2006) New cytokine targets in inflammatory rheumatic diseases. Best Practice and Research: Clinical Rheumatology, 20, pp. 865-878. (doi:10.1016/j.berh.2006.05.011)

Fitzgerald, O., and McInnes, I. (2006) Spondyloarthropathy: disease at the crossroads of immunity. Best Practice and Research: Clinical Rheumatology, 20, pp. 949-967. (doi:10.1016/j.berh.2006.06.010)

2005

Alvaro, J. et al. (2005) A multicentre, randomised, double blind, placebo controlled phase II study of subcutaneous interferon beta-1a in the treatment of patients with active rheumatoid arthritis. Annals of the Rheumatic Diseases, 64, pp. 64-69. (doi:10.1136/ard.2003.020347)

Baeten, D. et al. (2005) Synovial tissue analysis in clinical trials. Journal of Rheumatology, 32, pp. 2481-2484.

Baeten, D., Bresnihan, B., Gerlag, D., Haringman, J., Kraan, M., McInnes, I., Smeets, T., Tak, P., and Zwinderman, A. (2005) Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 64, pp. 834-838. (doi:10.1136/ard.2004.029751)

Baslund, B. et al. (2005) Targeting interleukin-15 in patients with rheumatoid arthritis - A proof-of-concept study. Arthritis and Rheumatism, 52, pp. 2686-2692. (doi:10.1002/art.21249)

Blackbourn, D., Gracie, J., McInnes, I., and Rezaee, S. (2005) Inhibition of neutrophil function by the Kaposi's sarcoma-associated herpesvirus vOX2 protein. AIDS, 19, pp. 1907-1910.

Chandler, D., Griffiths, C., Helliwell, P., Kyle, S., Lewis, J., McHugh, N., McInnes, I., Oliver, S., and Symmons, D. (2005) Guideline for anti-TNF-alpha therapy in psoriatic arthritis. Rheumatology, 44, pp. 390-397. (doi:10.1093/rheumatology/keh514)

Choo-Kang, B., Hutchison, S., Nickdel, M., Bundick, R., Leishman, A., Brewer, J., McInnes, I., and Garside, P. (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26, pp. 518-522. (doi:10.1016/j.it.2005.07.007)

Culshaw, S., Leung, B., Gracie, J., Campbell, C., Thomson, D., Gemmell, C., Liew, F., and McInnes, I. (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35, pp. 1438-1444. (doi:10.1002/ejui.200425661)

Gracie, J. et al. (2005) Disease association of two distinct interleukin-18 promoter polymorphisms in Caucasian rheumatoid arthritis patients. Genes and Immunity, 6, pp. 211-216. (doi:10.1038/sj.gene.6364183)

Gracie, J., Liew, F., and McInnes, I. (2005) Interleukin-18: A therapeutic target in rheumatoid arthritis? Commentary. Arthritis Research and Therapy, 7, pp. 38-41.

Kane, D., Lockhart, J., Balint, P., Mann, C., Ferrell, W., and McInnes, I. (2005) Protective effect of sensory denervation in inflammatory arthritis (evidence of regulatory neuroimmune pathways in the arthritic joint). Annals of the Rheumatic Diseases, 64(2), pp. 325-327.

Liew, F., and McInnes, I. (2005) A fork in the pathway to inflammation and arthritis. Nature Medicine, 11(6), pp. 601-602.

Liew, F., and McInnes, I. (2005) Cytokine networks - towards new therapies for rheumatoid arthritis. Nature Clinical Practice Rheumatology, 1, pp. 31-39. (doi:10.1038/ncprheum0020)

McInnes, I. (2005) Rheumatoid arthritis: of therapies and strategies. Current Opinion in Rheumatology, 17(3), pp. 271-273.

McInnes, I., and Sattar, N. (2005) Vascular comorbidity in rheumatoid arthritis: potential mechanisms and solutions. Current Opinion in Rheumatology, 17, pp. 286-292.

2004

McInnes, I.B., and Gracie, J.A. (2004) Targeting cytokines beyond tumor necrosis factor-alpha and interleukin-1 in rheumatoid arthritis. Current Rheumatology Reports, 6, pp. 336-342.

McInnes, I.B., and Gracie, J.A. (2004) Interleukin-15: a new cytokine target for the treatment of inflammatory diseases. Current Opinion in Pharmacology, 4(4), pp. 392-397. (doi:10.1016/j.coph.2004.04.003)

Leung, B.P., Xu, D., Culshaw, S., McInnes, I.B., and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173(1), pp. 145-150.

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I.B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173(1), pp. 151-156.

Harnett, W., McInnes, I.B., and Harnett, M.M. (2004) ES-62, a filarial nematode-derived immunomodulator with anti-inflammatory potential. Immunology Letters, 94(1-2), pp. 27-33. (doi:10.1016/j.imlet.2004.04.008)

McCarey, D.W., McInnes, I.B., Madhok, R., Hampson, R., Scherbakov, O., Ford, I., Capell, H., and Sattar, N. (2004) Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial. Lancet, 363(9426), pp. 2015-2021. (doi:10.1016/S0140-6736(04)16449-0)

McKay, A., Leung, B.P., McInnes, I.B., Thomson, N.C., and Liew, F.Y. (2004) A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. Journal of Immunology, 172(5), pp. 2903-2908.

Wilson, R., Moor, J., Jenkins, C., Miller, H., Walker, J.J., McLean, M.A., Norman, J., and McInnes, I.B. (2004) Abnormal first trimester serum interleukin 18 levels are associated with a poor outcome in women with a history of recurrent miscarriage. American Journal of Reproductive Immunology, 51(2), pp. 156-159. (doi:10.1046/j.8755-8920.2003.00126.x)

Alessandri, C., Barone, F., Blades, M., Bombardieri, M., Conigliaro, P., McInnes, I., Pittoni, V., Pitzalis, C., Priori, R., and Valesini, G. (2004) Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjogren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Research and Therapy, 6, R447-R456. (doi:10.1186/ar1209)

Bombardieri, M., Barone, F., Pittoni, P., Alessandri, C., Conigliaro, P., Blades, M.C., Priori, R., McInnes, I.B., Valesini, G., and Pitzalis, C. (2004) Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Research and Therapy, 6, R447-R456. (doi:10.1186/ar1209)

Capell, H., Madhok, R., McCarey, D., McInnes, I., and Sattar, N. (2004) Statins and rheumatoid arthritis - Reply. Lancet, 364(9448), p. 1855.

Harnett, W., Harnett, M.M., Leung, B.P., Gracie, J., and McInnes, I.B. (2004) The anti-inflammatory potential of the filarial nematode secreted product, ES-62. Current Topics in Medicinal Chemistry, 4(5), pp. 553-559. (doi:10.2174/1568026043451212)

2003

Sattar, N., McCarey, D.W., Capell, H., and McInnes, I.B. (2003) Explaining how "high-grade" systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation, 108(24), pp. 2957-2963. (doi:10.1161/01.CIR.0000099844.31524.05)

McInnes, I.B., Gracie, J.A., Harnett, M., Harnett, W., and Liew, F.Y. (2003) New strategies to control inflammatory synovitis: interleukin 15 and beyond. Annals of the Rheumatic Diseases, 62(2), pp. 51-54. (doi:10.1136/ard.62.suppl_2.ii51)

McInnes, I.B., Leung, B.P., Harnett, M., Gracie, J.A., Liew, F., and Harnett, W. (2003) A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62. Journal of Immunology, 171(4), pp. 2127-2133.

Wilson, R., Moore, J., Jenkins, C., Miller, H., Maclean, M.A., McInnes, I.B., and Walker, J.J. (2003) Abnormal IL-2 receptor levels in non-pregnant women with a history of recurrent miscarriage. Human Reproduction, 18(7), pp. 1529-1530. (doi:10.1093/humrep/deg287)

Gracie, J.A., Robertson, S.E., and McInnes, I.B. (2003) Interleukin-18. Journal of Leukocyte Biology, 73(2), pp. 213-224. (doi:10.1189/jlb.0602313)

Campbell, C. et al. (2003) A novel anti-inflammatory role for simvastatin in inflammatory arthritis. Journal of Immunology, 170, pp. 1524-1530.

Gracie, J., Komai-Koma, M., Liew, F., McInnes, I., Thomson, N., Wei, X., and Xu, D. (2003) Chemoattraction of human T cells by IL-18. Journal of Immunology, 170, pp. 1084-1090.

McInnes, I.B. (2003) Leukotrienes, mast cells, and T cells. Arthritis Research and Therapy, 5(6), pp. 288-289. (doi:10.1186/ar1017)

2002

Guillen, C., McInnes, I.B., Vaughan, D.M., Kommajosyula, S., Van Berkel, P.H.C.,, Leung, B.P., Aguila, A., and Brock, J.H. (2002) Enhanced Th1 response to Staphylococcus aureas infection in human lactoferrin-transgenic mice. Journal of Immunology, 168(8), pp. 3950-3957.

Balint, P., Kane, D., Hunter, J., McInnes, I., Field, M., and Sturrock, R. (2002) Ultrasound guided versus conventional joint and soft tissue fluid aspiration in rheumatology practice: A pilot study. Journal of Rheumatology, 29, pp. 2209-2213.

Balint, P., Kane, D., Wilson, H., McInnes, I., and Sturrock, R. (2002) Ultrasonography of entheseal insertions in the lower limb in spondyloarthropathy. Annals of the Rheumatic Diseases, 61, pp. 905-910.

Boumpas, D., Ikeuchi, H., Kaneko, Y., Kuroiwa, T., McInnes, I., Nojima, Y., Ota, F., Tanaka, T., Tsukada, Y., and Ueki, K. (2002) Human platelets stimulate mesangial cells to produce monocyte chemoattractant protein-1 via the CD40/CD40 ligand pathway and may amplify glomerular injury. Journal of the American Society of Nephrology, 13, pp. 2488-2496. (doi:10.1097/01.ASN.0000029588.07166.20)

Gracie, J., Leung, B., and McInnes, I. (2002) Novel pathways that regulate tumor necrosis factor-alpha production in rheumatoid arthritis. Current Opinion in Rheumatology, 14, pp. 270-275.

Leung, B., Conacher, M., Hunter, D., McInnes, I., Liew, F., and Brewer, J. (2002) A novel dendritic cell-induced model of erosive inflammatory arthritis: Distinct roles for dendritic cells in T cell activation and induction of local inflammation. Journal of Immunology, 169, pp. 7071-7077.

Liew, F., and McInnes, I. (2002) Role of interleukin 15 and interleukin 18 in inflammatory response. Annals of the Rheumatic Diseases, 61, pp. 100-102.

Liew, F., and McInnes, I. (2002) The role of innate mediators in inflammatory response. Molecular Immunology, 38, pp. 887-890.

2001

Arthur, H., Leung, B., Liew, F., McInnes, I., and Wei, X. (2001) Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. Journal of Immunology, 166, pp. 517-521.

Boumpas, D. et al. (2001) IL-10 improves skin disease and modulates endothelial activation and leukocyte effector function in patients with psoriatic arthritis. Journal of Immunology, 167, pp. 4075-4082.

Campbell, C., Canetti, C., Culshaw, S., Cunha, F., Gracie, J., Hunter, D., Leung, B., Liew, F., and McInnes, I. (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167, pp. 2879-2886.

Capell, H., Hamilton, J., Madhok, R., Mcinnes, I., and Wilson, H. (2001) The hip or not. Journal of Rheumatology, 28(6), pp. 1398-1400.

Capell, H., Hamilton, J., Hunter, J., Madhok, R., McInnes, I., Porter, D., and Thomson, E. (2001) Comparative study of intramuscular gold and methotrexate in a rheumatoid arthritis population from a socially deprived area. Annals of the Rheumatic Diseases, 60(6), pp. 566-572.

Capell, H., Hamilton, J., Madhok, R., McInnes, I., and Wilson, H. (2001) TNF alpha blockade in rheumatoid arthritis - Time for caution or enthusiasm? Scottish Medical Journal, 46(3), pp. 67-70.

Esfandiari, E., McInnes, I., Lindop, G., Huang, F., Field, M., Komai-Koma, M., Wei, X., and Liew, F. (2001) A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. Journal of Immunology, 167, pp. 5338-5347.

Gao, B., Gracie, J., Guan, H., Leung, B., Liew, F., McInnes, I., Niedbala, W., Orchardson, M., Paterson, G., and Wei, X. (2001) The sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo. Journal of Immunology, 167, pp. 277-282.

McCarey, D., McInnes, I., and Sattar, N. (2001) The antiinflammatory effects of statins. New England Journal of Medicine, 345(16), pp. 1209-1210.

McInnes, I. (2001) Rheumatoid arthritis - From bench to bedside. Rheumatic Disease Clinics of North America, 27, pp. 373-387.

2000

Leung, B., Liew, F., and McInnes, I. (2000) Cell-cell interactions in synovitis - Interactions between T lymphocytes and synovial cells. Arthritis Research, 2(5), pp. 374-378.

This list was generated on Fri Apr 24 18:26:25 2015 BST.
Number of items: 238.

Articles

Siebert, S., Tsoukas, A., Robertson, J., and McInnes, I. (2015) Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases. Pharmacological Reviews, 67(2), pp. 280-309. (doi:10.1124/pr.114.009639) (PMID:25697599)

Kelly, S. et al. (2015) Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients. Annals of the Rheumatic Diseases, 74(3), pp. 611-617. (doi:10.1136/annrheumdis-2013-204603) (PMID:24336336)

Hansell, C. A., MacLellan, L. M., Oldham, R. S., Doonan, J., Chapple, K. J., Anderson, E. J., Linington, C., McInnes, I. B., Nibbs, R. J., and Goodyear, C. S. (2015) The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens. Immunology and Cell Biology, 93(2), pp. 167-176. (doi:10.1038/icb.2014.90)

Moraitis, A. G. et al. (2015) Elevated interleukin-10: a new cause of dyslipidemia leading to severe HDL deficiency. Journal of Clinical Lipidology, 9(1), pp. 81-90. (doi:10.1016/j.jacl.2014.09.014) (PMID:25670364)

Platt, A. M., Benson, R. A., McQueenie, R., Butcher, J. P., Braddock, M., Brewer, J. M., McInnes, I. B., and Garside, P. (2015) The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4+ T cell-priming capacity of dendritic cells. Rheumatology, 54(1), pp. 169-177. (doi:10.1093/rheumatology/keu273) (PMID:25065010)

Kristensen, S. L., McInnes, I., and Sattar, N. (2015) Psoriasis, psoriatic arthritis and cardiovascular risk: are we closer to a clinical recommendation? Annals of the Rheumatic Diseases, 74(2), pp. 321-322. (doi:10.1136/annrheumdis-2014-206617)

Miller, N. L., Gilchrist, D., Akbar, M., Reilly, J. H., Kerr, S. C., Campbell, A. L., Murrell, G. A.C., Liew, F. Y., Kurowska-Stolarska, M., and McInnes, I. B. (2015) MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease. Nature Communications, 6, 6774. (doi:10.1038/ncomms7774)

Nanus, D.E., Filer, A.D., Hughes, B., Fisher, B.A., Taylor, P.C., Stewart, P.M., Buckley, C.D., McInnes, I., Cooper, M.S., and Raza, K. (2015) TNF regulates cortisol metabolism in vivo in patients with inflammatory arthritis. Annals of the Rheumatic Diseases, 74(2), pp. 464-469. (doi:10.1136/annrheumdis-2013-203926)

Robertson, J., McInnes, I., and Sattar, N. (2014) Response to ‘Interleukin-6 signal transduction and its role in hepatic lipid metabolic disorders’ by Hassan et al. Cytokine, 70(2), p. 198. (doi:10.1016/j.cyto.2014.05.028)

McInnes, I. B., and Siebert, S. (2014) Psoriatic arthritis - expanding options, exciting times? Acta Reumatologica Portuguesa, 39(4), pp. 294-295.

Kavanaugh, A. et al. (2014) Clinical efficacy, radiographic and safety findings through 5 years of subcutaneous golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of a randomised, placebo-controlled trial (the GO-REVEAL study). Annals of the Rheumatic Diseases, 73(9), pp. 1689-1694. (doi:10.1136/annrheumdis-2013-204902)

Meier, F. M.P., and McInnes, I. B. (2014) Small-molecule therapeutics in rheumatoid arthritis: Scientific rationale, efficacy and safety. Best Practice and Research: Clinical Rheumatology, 28(4), pp. 605-624. (doi:10.1016/j.berh.2014.10.017)

Nurmohamed, M. T., Jamnitski, A., Symmons, D., Peters, M. J. L., Sattar, N., and McInnes, I. (2014) Response to: 'The influence of inflammation in the development of subclinical atherosclerosis in psoriatic arthritis' by Gonzalez-Gay et al. Annals of the Rheumatic Diseases, 73(5), e28. (doi:10.1136/annrheumdis-2014-205174)

Rice, G. I. et al. (2014) Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling. Nature Genetics, 46(5), pp. 503-509. (doi:10.1038/ng.2933)

Patterson, H., Nibbs, R., McInnes, I., and Siebert, S. (2014) Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases. Clinical and Experimental Immunology, 176(1), pp. 1-10. (doi:10.1111/cei.12248)

Dale, J., Purves, D., McConnachie, A., McInnes, I., and Porter, D. (2014) Tightening up? Impact of musculoskeletal ultrasound disease activity assessment on early rheumatoid arthritis patients treated using a treat to target strategy. Arthritis Care and Research, 66(1), pp. 19-26. (doi:10.1002/acr.22218)

Dougados, M. et al. (2014) Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA). Annals of the Rheumatic Diseases, 73(1), pp. 62-68. (doi:10.1136/annrheumdis-2013-204223)

Frleta, M., Siebert, S., and McInnes, I. B. (2014) The interleukin-17 pathway in psoriasis and psoriatic arthritis: disease pathogenesis and possibilities of treatment. Current Rheumatology Reports, 16(414), (doi:10.1007/s11926-014-0414-y)

Kavanaugh, A. et al. (2014) Ustekinumab, an anti-IL-12/23 p40 monoclonal antibody, inhibits radiographic progression in patients with active psoriatic arthritis: results of an integrated analysis of radiographic data from the phase 3, multicentre, randomised, double-blind, placebo-controlled PSUMMIT-1 and PSUMMIT-2 trials. Annals of the Rheumatic Diseases, 73(6), pp. 1000-1006. (doi:10.1136/annrheumdis-2013-204741) (PMID:24553909) (PMCID:PMC4033146)

McInnes, I.B. et al. (2014) Open-label tofacitinib and double-blind atorvastatin in rheumatoid arthritis patients: a randomised study. Annals of the Rheumatic Diseases, 73(1), pp. 124-131. (doi:10.1136/annrheumdis-2012-202442)

McInnes, I.B. et al. (2014) Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial. Annals of the Rheumatic Diseases, 73(2), pp. 349-356. (doi:10.1136/annrheumdis-2012-202646)

Paul, L., Rafferty, D., Marshall-Mckenna, R., Gill, J.M.R., McInnes, I., Porter, D., and Woodburn, J. (2014) Oxygen cost of walking, physical activity, and sedentary behaviours in rheumatoid arthritis. Scandinavian Journal of Rheumatology, 43(1), pp. 28-34. (doi:10.3109/03009742.2013.802009)

Ritchlin, C. et al. (2014) Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional non-biological and biological anti-tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, double-blind, placebo-controlled, randomised PSUMMIT 2 trial. Annals of the Rheumatic Diseases, 73(6), pp. 990-999. (doi:10.1136/annrheumdis-2013-204655) (PMID:24482301) (PMCID:PMC4033144)

Stalmach, A., Johnsson, H., McInnes, I. B., Husi, H., Klein, J., Dakna, M., Mullen, W., Mischak, H., and Porter, D. (2014) Identification of urinary peptide biomarkers associated with rheumatoid arthritis. PLoS ONE, 9(8), e104625. (doi:10.1371/journal.pone.0104625)

Turner, D. E., Hyslop, E., Barn, R., McInnes, I. B., Steultjens, M. P.M., and Woodburn, J. (2014) Metatarsophalangeal joint pain in psoriatic arthritis: a cross-sectional study. Rheumatology, 53(4), pp. 737-740. (doi:10.1093/rheumatology/ket435)

Lappin, D.F., Apatzidou, D., Quirke, A.M., Oliver-Bell, J., Butcher, J.P., Kinane, D.F., Riggio, M.P., Venables, P., McInnes, I.B., and Culshaw, S. (2013) Influence of periodontal disease, porphyromonas gingivalisand cigarette smoking on systemic anti-citrullinated peptide antibody titres. Journal of Clinical Periodontology, 40(10), pp. 907-915. (doi:10.1111/jcpe.12138)

van den Berg, W.B., and McInnes, I.B. (2013) Th17 cells and IL-17 A—Focus on immunopathogenesis and immunotherapeutics. Seminars in Arthritis and Rheumatism, 43(2), pp. 158-170. (doi:10.1016/j.semarthrit.2013.04.006)

Robertson, J., Peters, M.J., McInnes, I.B., and Sattar, N. (2013) Changes in lipid levels with inflammation and therapy in RA: a maturing paradigm. Nature Reviews Rheumatology, 9(9), pp. 513-523. (doi:10.1038/nrrheum.2013.91)

McInnes, I.B. et al. (2013) Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial. Lancet, 382(9894), pp. 780-789. (doi:10.1016/S0140-6736(13)60594-2)

Schett, G., Elewaut, D., McInnes, I.B., Dayer, J.-M., and Neurath, M.F. (2013) How cytokine networks fuel inflammation: toward a cytokine-based disease taxonomy. Nature Medicine, 19(7), pp. 822-824. (doi:10.1038/nm.3260)

Weir, R. A.P. et al. (2013) Response to letter regarding article, "Galectin-3 and cardiac function in survivors of acute myocardial infarction". Circulation: Heart Failure, 6(4), e58. (doi:10.1161/CIRCHEARTFAILURE.113.000382)

Kapoor, S.R., Filer, A., Fitzpatrick, M.A., Fisher, B.A., Taylor, P.C., Buckley, C.D., McInnes, I.B., Raza, K., and Young, S.P. (2013) Metabolic profiling predicts response to anti-tumor necrosis factor α therapy in patients with rheumatoid arthritis. Arthritis and Rheumatism, 65(6), pp. 1448-1456. (doi:10.1002/art.37921)

Weir, R. A.P. et al. (2013) Galectin-3 and cardiac function in survivors of acute myocardial infarction. Circulation: Heart Failure, 6(3), pp. 492-498. (doi:10.1161/CIRCHEARTFAILURE.112.000146)

Villeneuve, E. et al. (2013) Republished: a systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Postgraduate Medical Journal, 89(1050), pp. 231-240. (doi:10.1136/postgradmedj-2011-201063rep)

van der Heijde, D. et al. (2013) EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria. Annals of the Rheumatic Diseases, 72(4), pp. 479-481. (doi:10.1136/annrheumdis-2012-202779)

O'Shea, J.J., Laurence, A., and McInnes, I.B. (2013) Back to the future: oral targeted therapy for RA and other autoimmune diseases. Nature Reviews Rheumatology, 9(3), pp. 173-182. (doi:10.1038/nrrheum.2013.7)

Villeneuve, E. et al. (2013) A systematic literature review of strategies promoting early referral and reducing delays in the diagnosis and management of inflammatory arthritis. Annals of the Rheumatic Diseases, 72(1), pp. 13-22. (doi:10.1136/annrheumdis-2011-201063)

Wagner, C.L. et al. (2013) Markers of inflammation and bone remodelling associated with improvement in clinical response measures in psoriatic arthritis patients treated with golimumab. Annals of the Rheumatic Diseases, 72(1), pp. 83-88. (doi:10.1136/annrheumdis-2012-201697)

Asquith, D.L. et al. (2013) The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release. Annals of the Rheumatic Diseases, 72(12), pp. 2024-2031. (doi:10.1136/annrheumdis-2012-202872)

Coates, L.C. et al. (2013) The 2012 BSR and BHPR guideline for the treatment of psoriatic arthritis with biologics. Rheumatology, 52(10), pp. 1754-1757. (doi:10.1093/rheumatology/ket187)

Crilly, A., Palmer, H.S., Nickdel, M.B., Dunning, L., Lockhart, J.C., Plevin, R., McInnes, I.B., and Ferrell, W.R. (2013) Immunomodulatory role of proteinase-activated receptor-2. Annals of the Rheumatic Diseases, 71(9), pp. 1559-1566. (doi:10.1136/annrheumdis-2011-200869)

Jamnitski, A., Symmons, D., Peters, M.J.L., Sattar, N., McInnes, I., and Nurmohamed, M.T. (2013) Cardiovascular comorbidities in patients with psoriatic arthritis: a systematic review. Annals of the Rheumatic Diseases, 72(2), pp. 211-216. (doi:10.1136/annrheumdis-2011-201194)

Kavanaugh, A. et al. (2013) Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study. Annals of the Rheumatic Diseases, 72(11), pp. 1777-1785. (doi:10.1136/annrheumdis-2012-202035)

McInnes, I.B., Combe, B., and Burmester, G. (2013) Understanding the patient perspective: results of the rheumatoid arthritis: insights, strategies and expectations (RAISE) patient needs survey. Clinical and Experimental Rheumatology, 31(3), pp. 350-7.

Millar, N., Murrell, G.A.C., and McInnes, I. (2013) Alarmins in tendinopathy: unravelling new mechanisms in a common disease. Rheumatology, 52(5), pp. 769-779.

Miller, A. M., Gilchrist, D. S., Nijjar, J., Araldi, E., Ramirez, C. M., Lavery, C. A., Fernández-Hernando, C., McInnes, I. B., and Kurowska-Stolarska, M. (2013) MiR-155 has a protective role in the development of non-alcoholic hepatosteatosis in mice. PLoS ONE, 8(8), e72324. (doi:10.1371/journal.pone.0072324)

Nijjar, J., Tindell, A., McInnes, I.B., and Siebert, S. (2013) Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis. Rheumatology, 52(9), pp. 1556-1562. (doi:10.1093/rheumatology/ket225)

Steven, R., Crilly, A., Lockhart, J. C., Ferrell, W. R., and McInnes, I. B. (2013) Proteinase-activated receptor-2 modulates human macrophage differentiation andeffector function. Innate Immunity, 19(6), pp. 663-672. (doi:10.1177/1753425913479984)

Miller, A. M., Xu, D., Asquith, D. L., Denby, L., Li, Y., Sattar, N., Baker, A. H., McInnes, I. B., and Liew, F. Y. (2012) IL-33 reduces the development of atherosclerosis (vol 205, pg 339, 2008). Journal of Experimental Medicine, 209(13), p. 2515. (doi:10.1084/jem.2007186820913c)

MacRitchie, N. et al. (2012) Plasmacytoid dendritic cells play a key role in promoting atherosclerosis in apolipoprotein e-deficient mice. Arteriosclerosis, Thrombosis and Vascular Biology, 32(11), pp. 2569-2579. (doi:10.1161/ATVBAHA.112.251314)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B bell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Miller, A. M. et al. (2012) Soluble ST2 associates with diabetes but not established cardiovascular risk factors: a new inflammatory pathway of relevance to diabetes? PLoS ONE, 7(10), e47830. (doi:10.1371/journal.pone.0047830)

Haneklaus, M., Gerlic, M., Kurowska-Stolarska, M., Rainey, A.-A., Pich, D., McInnes, I.B., Hammerschmidt, W., O'Neill, L.A.J., and Masters, S.L. (2012) Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1 production. Journal of Immunology, 189(8), pp. 3795-3799. (doi:10.4049/jimmunol.1200312)

Keystone, E. C., Wang, M. M., Layton, M., Hollis, S., and McInnes, I.B. (2012) Clinical evaluation of the efficacy of the P2X7 purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine. Annals of the Rheumatic Diseases, 71(10), pp. 1630-1635. (doi:10.1136/annrheumdis-2011-143578)

Utriainen, L., Firmin, D., Wright, P., Cerovic, V., Breban, M., McInnes, I., and Milling, S. (2012) Expression of HLA-B27 causes loss of migratory dendritic cells in a rat model of spondylarthritis. Arthritis and Rheumatism, 64(10), pp. 3199-3209. (doi:10.1002/art.34561)

Weir, R. A.P., Miller, A. M., Petrie, C. J., Clements, S., Steedman, T., Dargie, H. J., Squire, I. B., Ng, L. L., McInnes, I. B., and McMurray, J. J.V. (2012) Interleukin-21 – a biomarker of importance in predicting myocardial function following acute infarction? Cytokine, 60(1), pp. 220-225. (doi:10.1016/j.cyto.2012.06.002)

Singh, M.D. et al. (2012) Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis. American Journal of Pathology, 181(4), pp. 1158-1164. (doi:10.1016/j.ajpath.2012.06.042)

Tindell, A.G., Kelso, E.B., Ferrell, W.R., Lockhart, J.C., Walsh, D.A., Dunning, L., and McInnes, I.B. (2012) Correlation of protease-activated receptor-2 expression and synovitis in rheumatoid and osteoarthritis. Rheumatology International, 32(10), pp. 3077-3086. (doi:10.1007/s00296-011-2102-9)

Komai-Koma, M. et al. (2012) Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice. Allergy, 67(9), pp. 1118-1126. (doi:10.1111/j.1398-9995.2012.02859.x)

Kavanaugh, A. et al. (2012) Golimumab in psoriatic arthritis: one-year clinical efficacy, radiographic, and safety results from a phase III, randomized, placebo-controlled trial. Arthritis and Rheumatism, 64(8), pp. 2504-2517. (doi:10.1002/art.34436)

McInnes, I., Lee, J.S., Thompson, L., Giles, J.T., Bathton, J.M., Salmon, J.E., Beaulieu, A.D., Codding, C.E., Delles, C., and Sattar, N. (2012) The effects of tocilizumab treatment on lipids and inflammatory/prothrombotic markers in patients (pts) with rheumatoid arthritis (RA): data from the randomized, controlled, measure study. European Heart Journal, 33(Sup 1), p. 281. (doi:10.1093/eurheartj/ehs281)

Crilly, A. et al. (2012) PAR2 expression in peripheral blood monocytes of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71(6), pp. 1049-1054. (doi:10.1136/annrheumdis-2011-200703)

Gibson, V.B. et al. (2012) A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood, 119(11), pp. 2545-2551. (doi:10.1182/blood-2011-09-378356)

Baxter, D., McInnes, I.B., and Kurowska-Stolarska, M. (2012) Novel regulatory mechanisms in inflammatory arthritis: a role for microRNA. Immunology and Cell Biology, 90(3), pp. 288-292. (doi:10.1038/icb.2011.114)

Frleta, M., King, V., Reilly, J.H., Gilchrist, D.S., Tornehave, D., Lundsgaard, D., Miller, A.M., and McInnes, I.B. (2012) Expression of IL-21 receptor in synovial tissue and blood of patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 71(Sup. 1), A83. (doi:10.1136/annrheumdis-2011-201238.25)

Gossec, L. et al. (2012) European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Annals of the Rheumatic Diseases, 71(1), pp. 4-12. (doi:10.1136/annrheumdis-2011-200350)

Henningsson, L., Jirholt, P., Bogestal, Y.R., Eneljung, T., Adiels, M., Lindholm, C., McInnes, I., Bulfone-Paus, S., Lerner, U.H., and Gjertsson, I. (2012) Interleukin 15 mediates joint destruction in Staphylococcus aureus arthritis. Journal of Infectious Diseases, 206(5), pp. 687-696. (doi:10.1093/infdis/jis295)

Johnsson, H., McInnes, I.B., and Sattar, N. (2012) Cardiovascular and metabolic risks in psoriasis and psoriatic arthritis: pragmatic clinical management based on available evidence. Annals of the Rheumatic Diseases, 71(4), pp. 480-483. (doi:10.1136/annrheumdis-2011-200567)

Kerekes, G., Soltész, P., Nurmohamed, M.T., Gonzalez-Gay, M.A., Turiel, M., Végh, E., Shoenfeld, Y., McInnes, I., and Szekanecz, Z. (2012) Validated methods for assessment of subclinical atherosclerosis in rheumatology. Nature Reviews Rheumatology, 8(4), pp. 224-234. (doi:10.1038/nrrheum.2012.16)

Lories, R.J., and McInnes, I.B. (2012) Primed for inflammation: enthesis-resident T cells. Nature Medicine, 18(7), pp. 1018-1019. (doi:10.1038/nm.2854)

McQueenie, R., Stevenson, R., Benson, R., MacRitchie, N., McInnes, I., Maffia, P., Faulds, K., Graham, D., Brewer, J., and Garside, P. (2012) Detection of inflammation in vivo by surface-enhanced raman scattering provides higher sensitivity than conventional fluorescence imaging. Analytical Chemistry, 84(14), pp. 5968-5975. (doi:10.1021/ac3006445)

Millar, N.L., Reilly, J.H., Kerr, S.C., Campbell, A.L., Little, K.J., Leach, W.J., Rooney, B.P., Murrell, G.A.C., and McInnes, I.B. (2012) Hypoxia: a critical regulator of early human tendinopathy. Annals of the Rheumatic Diseases, 71(2), pp. 302-310. (doi:10.1136/ard.2011.154229)

Patakas, A., Benson, R.A., Withers, D.R., Conigliaro, P., McInnes, I.B., Brewer, J.M., and Garside, P. (2012) Th17 effector cells support B cell responses outside of germinal centres. PLoS ONE, 7(11), e49715. (doi:10.1371/journal.pone.0049715)

Steinman, L., Merrill, J.T., McInnes, I.B., and Peakman, M. (2012) Optimization of current and future therapy for autoimmune diseases. Nature Medicine, 18(1), pp. 59-65. (doi:10.1038/nm.2625)

Wenink, M.H., Santegoets, K.C.M., Platt, A.M., van den Berg, W.B., van Riel, P.L.C.M., Garside, P., Radstake, T.R.D.J., and McInnes, I.B. (2012) Abatacept modulates proinflammatory macrophage responses upon cytokine-activated T cell and Toll-like receptor ligand stimulation. Annals of the Rheumatic Diseases, 71(1), pp. 80-83. (doi:10.1136/annrheumdis-2011-200348)

Xuzhu, G., Komai-Koma, M., Leung, B.P., Howe, H.S., McSharry, C., McInnes, I.B., and Xu, D. (2012) Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function. Annals of the Rheumatic Diseases, 71(1), pp. 129-135. (doi:10.1136/ard.2011.149831)

McInnes, I.B., and Schett, G. (2011) The pathogenesis of rheumatoid arthritis. New England Journal of Medicine, 365(23), pp. 2205-2219. (doi:10.1056/NEJMra1004965)

Benson, R.A., Patakas, A., McQueenie, R., Ross, K., McInnes, I.B., Brewer, J.M., and Garside, P. (2011) Arthritis in space and time – to boldly go! FEBS Letters, 585(23), pp. 2640-3648. (doi:10.1016/j.febslet.2011.04.069)

Wenink, M.H., Santegoets, K.C.M., Butcher, J., van Bon, L., Lamers-Karnebeek, F.G.M., van den Berg, W.B., van Riel, P.L.C.M., McInnes, I.B., and Radstake, T.R.D.J. (2011) Impaired dendritic cell proinflammatory cytokine production in psoriatic arthritis. Arthritis and Rheumatism, 63(11), pp. 3313-3322. (doi:10.1002/art.30577)

Welsh, P. et al. (2011) Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. Arteriosclerosis, Thrombosis and Vascular Biology, 31(10), pp. 2338-2344. (doi:10.1161/ATVBAHA.111.231795)

Hueber, A. J., Alves-Filho, J. C., Asquith, D. L., Michels, C. , Millar, N. L., Reilly, J. H., Graham, G. J., Liew, F. Y., Miller, A. M., and McInnes, I. B. (2011) IL-33 induces skin inflammation with mast cell and neutrophil activation. European Journal of Immunology, 41(8), pp. 2229-2237. (doi:10.1002/eji.201041360)

Conigliaro, P., Benson, R.A., Patakas, A., Kelly, S.M., Valesini, G., Homdahl, R., Brewer, J.M., McInnes, I.B., and Garside, P. (2011) Characterization of the anti-collagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63(8), pp. 2299-2308. (doi:10.1002/art.30413)

Conigliaro, P., Benson, R. A., Patakas, A., Kelly, S. M., Valesini, G., Holmdahl, R., Brewer, J. M., McInnes, I. B., and Garside, P. (2011) Characterization of the anticollagen antibody response in a new model of chronic polyarthritis. Arthritis and Rheumatism, 63(8), pp. 2299-2308. (doi:10.1002/art.30413)

Kurowska-Stolarska, M. et al. (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proceedings of the National Academy of Sciences of the United States of America, 108(27), pp. 11193-11198. (doi:10.1073/pnas.1019536108)

Patakas, A., Platt, A. M., Butcher, J. P., Maffia, P., McInnes, I. B., Brewer, J. M., Garside, P., and Benson, R. A. (2011) Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease. Immunology Letters, 138(1), pp. 38-46. (doi:10.1016/j.imlet.2011.03.002)

Zaiss, M. M. et al. (2011) IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-α–mediated bone loss. Journal of Immunology, 186(11), pp. 6097-6105. (doi:10.4049/jimmunol.1003487)

Welsh, P. et al. (2011) Vitamin D deficiency is common in patients with RA and linked to disease activity, but circulating levels are unaffected by TNF blockade: results from a prospective cohort study. Annals of the Rheumatic Diseases, 70(6), pp. 1165-1167. (doi:10.1136/ard.2010.137265)

Hansell, C. A. H., Schiering, C., Kinstrie, R., Ford, L., Bordon, Y., McInnes, I. B., Goodyear, C. S., and Nibbs, R. J.B. (2011) Universal expression and dual function of the atypical chemokine receptor D6 on innate-like B cells in mice. Blood, 117(20), pp. 5413-5424. (doi:10.1182/blood-2010-11-317115)

Krishnadas, R., Mallon, V., McInnes, I., and Cavanagh, J. (2011) Correlates of depression and quality of life in patients with inflammatory arthritides. European Psychiatry, 26, p. 383. (doi:10.1016/S0924-9338(11)72091-0)

Norman, J.E., Yuan, M., Anderson, L., Howie, F., Harold, G., Young, A., Jordan, F., McInnes, I., and Harnett, M.M. (2011) Effect of prolonged in vivo administration of progesterone in pregnancy on myometrial gene expression, peripheral blood leukocyte activation, and circulating steroid hormone levels. Reproductive Sciences, 18(5), pp. 435-446. (doi:10.1177/1933719110395404)

Culshaw, S., McInnes, I. B., and Liew, F. Y. (2011) What can the periodontal community learn from the pathophysiology of rheumatoid arthritis? Journal of Clinical Periodontology, 38(S11), pp. 106-113. (doi:10.1111/j.1600-051X.2010.01669.x)

Codullo, V. et al. (2011) An investigation of the inflammatory cytokine and chemokine network in systemic sclerosis. Annals of the Rheumatic Diseases, 70(6), pp. 1115-1121. (doi:10.1136/ard.2010.137349 )

Miller, A., and McInnes, I. (2011) Cytokines as therapeutic targets to reduce cardiovascular risk in chronic inflammation. Current Pharmaceutical Design, 17(1), pp. 1-8. (doi:10.2174/138161211795049796)

Asquith, D.L., Miller, A.M., Reilly, J.H., Kerr, S., Welsh, P., Sattar, N., and McInnes, I.B. (2011) Simultaneous activation of the liver X receptors (LXR and LXR) drives murine collagen-induced arthritis disease pathology. Annals of the Rheumatic Diseases, 70(12), pp. 2225-2228. (doi:10.1136/ard.2011.152652)

Bombardieri, M., Kam, N.-W., Brentano, F., Choi, K., Filer, A., Kyburz, D., McInnes, I.B., Gay, S., Buckley, C., and Pitzalis, C. (2011) A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells. Annals of the Rheumatic Diseases, 70(10), pp. 1857-1865. (doi:10.1136/ard.2011.150219)

Crilly, A., Robertson, S.E., Reilly, J.H., Gracie, J.A., Lai, W.-Q., Leung, B.P., Life, P.F., and McInnes, I.B. (2011) Phosphodiesterase 4 (PDE4) regulation of proinflammatory cytokine and chemokine release from rheumatoid synovial membrane. Annals of the Rheumatic Diseases, 70(6), pp. 1130-1137. (doi:10.1136/ard.2010.134825)

Laing, S., Hernandez-Santana, A., Sassmannshausen, J., Asquith, D.L., McInnes, I.B., Faulds, K., and Graham, D. (2011) Quantitative Detection of Human Tumor Necrosis Factor α by a Resonance Raman Enzyme-Linked Immunosorbent Assay. Analytical Chemistry, 83(1), pp. 297-302. (doi:10.1021/ac1024039)

MacLellan, L.M., Montgomery, J., Sugiyama, F., Kitson, S.M., Thümmler, K., Silverman, G.J., Beers, S.A., Nibbs, R.J.B., McInnes, I.B., and Goodyear, C.S. (2011) Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice. Arthritis and Rheumatism, 63(12), pp. 3897-3907. (doi:10.1002/art.30629)

Pitman, N., Asquith, D.L., Murphy, G., Liew, F.Y., and McInnes, I.B. (2011) Collagen-induced arthritis is not impaired in mast cell-deficient mice. Annals of the Rheumatic Diseases, 70(6), pp. 1170-1171. (doi:10.1136/ard.2010.134528)

Zwerina, K. et al. (2011) Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance. European Journal of Immunology, 42(2), pp. 413-423. (doi:10.1002/eji.201141871)

van de Sande, M. G. H. et al. (2011) Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials. Annals of the Rheumatic Diseases, 70(3), pp. 423-427. (doi:10.1136/ard.2010.139550)

Miller, A. M., Asquith, D. L., Hueber, A. J., Anderson, L. A., Holmes, W. M., McKenzie, A. N., Xu, D., Sattar, N., McInnes, I. B., and Liew, F. Y. (2010) Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice. Circulation Research, 107(5), pp. 650-658. (doi:10.1161/CIRCRESAHA.110.218867)

Verri, W. A. et al. (2010) IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Annals of the Rheumatic Diseases, 69(9), pp. 1697-1703. (doi:10.1136/ard.2009.122655)

Emery, P., Buch, M.H., Östör, A., Kirkham, B., Taylor, P., Estrach, C., Jenkinson, T., McInnes, I., and Porter, D. (2010) Time for treatment targets in rheumatoid arthritis. British Medical Journal, 341(c4170), p. 267. (doi:10.1136/bmj.c4170)

Platt, A. M., Gibson, V. B., Patakas, A., Benson, R. A., Nadler, S. G., Brewer, J. M., McInnes, I., and Garside, P. (2010) Abatacept limits breach of self-tolerance in a Murine model of arthritis via effects on the generation of T follicular helper cells. Journal of Immunology, 185(3), pp. 1558-1567. (doi:10.4049/jimmunol.1001311 )

Benson, R.A., Patakas, A., Conigliaro, P., Rush, C. M., Garside, P., McInnes, I. B., and Brewer, J. M. (2010) Identifying the Cells Breaching Self-Tolerance in Autoimmunity. Journal of Immunology, 184(11), pp. 6378-6385. (doi:10.4049/jimmunol.0903951)

Hueber, A. J., Asquith, D. L., Miller, A. M., Reilly, J., Kerr, S., Leipe, J., Melendez Romero, A. J., and McInnes, I. B. (2010) Cutting Edge: Mast Cells Express IL-17A in Rheumatoid Arthritis Synovium. Journal of Immunology, 184(7), pp. 3336-3340. (doi:10.4049/jimmunol.0903566)

Xu, D. et al. (2010) IL-33 exacerbates autoantibody-induced arthritis. Journal of Immunology, 184(5), pp. 2620-2626. (doi:10.4049/jimmunol.0902685)

Asquith, D. L., Miller, A. M., Hueber, A. J., Liew, F. Y., Sattar, N., and McInnes, I. B. (2010) Apolipoprotein E-deficient mice are resistant to the development of collagen-induced arthritis. Arthritis and Rheumatism, 62(2), pp. 472-477. (doi:10.1002/art.27205)

Liew, F. Y., Pitman, N. I., and McInnes, I. B. (2010) Disease-associated functions of IL-33: the new kid in the IL-1 family. Nature Reviews Immunology, 10(2), pp. 103-110. (doi:10.1038/nri2692)

Weir, R.A.P., Miller, A.M., Murphy, G., Clements, S., Steedman, T., Connell, J., McInnes, I., Dargie, H., and McMurray, J.J. (2010) Serum soluble ST2 a potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction. Journal of the American College of Cardiology, 55(3), pp. 243-250. (doi:10.1016/j.jacc.2009.08.047)

Murphy, G.E.J., Xu, D., Liew, F.Y., and McInnes, I.B. (2010) Role of interleukin 33 in human immunopathology. Annals of the Rheumatic Diseases, 69(Suppl ), pp. 43-47. (doi:10.1136/ard.2009.120113)

Cavanagh, J., Paterson, C., McLean, J., Pimlott, S., McDonald, M., Patterson, J., Wyper, D., and McInnes, I. (2010) Tumour necrosis factor blockade mediates altered serotonin transporter availability in rheumatoid arthritis: a clinical, proof-of-concept study. Annals of the Rheumatic Diseases, 69(6), 1251-U367. (doi:10.1136/ard.2009.107912)

Ferrell, W.R., Kelso, E.B., Lockhart, J.C., Plevin, R., and McInnes, I.B. (2010) Protease-activated receptor 2: a novel pathogenic pathway in a murine model of osteoarthritis. Annals of the Rheumatic Diseases, 69(11), pp. 2051-2054. (doi:10.1136/ard.2010.130336)

Fraser, A.R., Perry, M.E., Crilly, A., Reilly, J.H., Hueber, A.J., and McInnes, I.B. (2010) Lipoma arborescens co-existing with psoriatic arthritis releases tumour necrosis factor alpha and matrix metalloproteinase. Annals of the Rheumatic Diseases, 69(4), pp. 776-777. (doi:10.1136/ard.2008.106047)

Hueber, A.J., Asquith, D.L., McInnes, I.B., and Miller, A.M. (2010) Embracing novel cytokines in RA – complexity grows as does opportunity! Best Practice and Research: Clinical Rheumatology, 24(4), pp. 479-487. (doi:10.1016/j.berh.2010.01.004)

Hyslop, E., McInnes, I. B., Woodburn, J., and Turner, D. E. (2010) Foot problems in psoriatic arthritis: high burden and low care provision. Annals of the Rheumatic Diseases, 69(5), p. 928. (doi:10.1136/ard.2009.111971)

Hyslop, E., Woodburn, J., McInnes, I.B., Semple, R., Newcombe, L., Hendry, G., Rafferty, D., De Mits, S., and Turner, D.E. (2010) A reliability study of biomechanical foot function in psoriatic arthritis based on a novel multi-segmented foot model. Gait and Posture, 32(4), pp. 619-626. (doi:10.1016/j.gaitpost.2010.09.004)

Kurowska-Stolarska, M., Hueber, A., Stolarski, B., and McInnes, I. B. (2010) Interleukin-33: a novel mediator with a role in distinct disease pathologies. Journal of Internal Medicine, 269(1), pp. 29-35. (doi:10.1111/j.1365-2796.2010.02316.x)

McInnes, I. B., and O'Dell, J. R. (2010) State-of-the-art: rheumatoid arthritis. Annals of the Rheumatic Diseases, 69(11), pp. 1898-1906. (doi:10.1136/ard.2010.134684)

Millar, N.L., Hueber, A.J., Reilly, J.H., Xu, Y., Fazzi, U.G., Murrell, G.A.C., and McInnes, I.B. (2010) Inflammation is present in early human tendinopathy. American Journal of Sports Medicine, 38(10), pp. 2085-2091. (doi:10.1177/0363546510372613)

Kurowska-Stolarska, M. et al. (2009) IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation. Journal of Immunology, 183(10), pp. 6469-6477. (doi:10.4049/jimmunol.0901575)

Lai, W.-Q., Irwan, A. W., Goh, H. H., Melendez, A. J., McInnes, I. B., and Leung, B. P. (2009) Distinct Roles of Sphingosine Kinase 1 and 2 in Murine Collagen-Induced Arthritis. Journal of Immunology, 183(3), pp. 2097-2103. (doi:10.4049/jimmunol.0804376)

Asquith, D. L., Miller, A. M., McInnes, I. B. , and Liew, F. Y. (2009) Animal models of rheumatoid arthritis. European Journal of Immunology, 39(8), pp. 2040-2044. (doi:10.1002/eji.200939578 )

McKimmie, C. S. et al. (2009) A TLR2 ligand suppresses inflammation by modulation of chemokine receptors and redirection of leukocyte migration. Blood, 113(18), pp. 4224-4231. (doi:10.1182/blood-2008-08-174698 )

Lemos, H. P. et al. (2009) Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ  production. Proceedings of the National Academy of Sciences of the United States of America, 106(14), pp. 5954-5959. (doi:10.1073/pnas.0812782106)

Jongbloed, S.L., Benson, R., Nickdel, M.B., Garside, P., McInnes, I., and Brewer, J.M. (2009) Plasmacytoid dendritic cells regulate breach of self-tolerance in autoimmune arthritis. Journal of Immunology, 182(2), pp. 963-968.

Asquith, D., Miller, A., Hueber, A., McKinnon, H., Sattar, N., Graham, G., and McInnes, I. (2009) Liver X Receptor Agonism Promotes Articular Inflammation in Murine Collagen-Induced Arthritis. Arthritis and Rheumatism, 60(9), pp. 2655-2665. (doi:10.1002/art.24717 )

Asquith, D.L., Miller, A.L., McInnes, I.B., and Liew, F.Y. (2009) Autoimmune disease: rheumatoid arthritis. Animal models of rheumatoid arthritis. European Journal of Immunology, 39, pp. 1991-2058.

Conigliaro, P., Priori, R., Bombardieri, M., Alessandri, C., Barone, F., Pitzalis, C., McInnes, I., and Valesini, G. (2009) Lymph node IL-18 expression in adult-onset Still's disease. Annals of the Rheumatic Diseases, 68(3), pp. 442-443.

Gabay, C., and McInnes, I. (2009) The biological and clinical importance of the 'new generation' cytokines in rheumatic diseases. Arthritis Research and Therapy, 11(3),

Hueber, A., and McInnes, I. (2009) Is spleen tyrosine kinase inhibition an effective therapy for patients with RA? Nature Clinical Practice Rheumatology, 5(3), pp. 130-131.

Hueber, A., Stevenson, R., Stokes, R., Graham, D., Garside, P., and McInnes, I. (2009) Imaging inflammation in real time-future of nanoparticles. Autoimmunity, 42(4), pp. 368-372.

Hutchison, S., Choo-Kang, B.S.W., Gibson, V.B., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2009) An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation. Clinical and Experimental Immunology, 155(1), pp. 107-116.

McInnes, I. (2009) Does practice mirror the evidence base in the treatment of rheumatoid arthritis? Clinical Rheumatology, 28(8), pp. 961-970.

McKellar, G., McCarey, D., Sattar, N., and McInnes, I. (2009) Role for TNF in atherosclerosis? Lessons from autoimmune disease. Nature Reviews Cardiology, 6(6), pp. 410-417.

Nickdel, M.B., Conigliaro, P., Valesini, G., Hutchison, S., Benson, R., Bundick, R.V., Leishman, A.J., McInnes, I., Brewer, J.M., and Garside, P. (2009) Dissecting the contribution of innate and antigen-specific pathways to the breach of self-tolerance observed in a murine model of arthritis. Annals of the Rheumatic Diseases, 68(6), pp. 1059-1066. (doi:10.1136/ard.2008.089300)

Patel, M., McInnes, I., and Graham, G. (2009) Atypical Chemokine Receptors in Inflammatory Disease. Current Molecular Medicine, 9(1), pp. 86-93.

Yuan, M., Jordan, F., McInnes, I., Harnett, M., and Norman, J. (2009) Leukocytes are primed in peripheral blood for activation during term and preterm labour. Molecular Human Reproduction, 15(11), pp. 713-724. (doi:10.1093/molehr/gap054)

Lai, W.-Q., Irwan, A. W., Goh, H. H., Howe, H. S., Yu, D. T., Valle-Onate, R., McInnes, I. B., Melendez, A. J., and Leung, B. P. (2008) Anti-Inflammatory Effects of Sphingosine Kinase Modulation in Inflammatory Arthritis. Journal of Immunology, 181(11), pp. 8010-8017.

Niedbala, W., Cai, B., Wei, X., Patakas, A., Leung, B. P., McInnes, I., and Liew, F. Y. (2008) Interleukin 27 attenuates collagen-induced arthritis. Annals of the Rheumatic Diseases, 67(10), pp. 1474-1479. (doi:10.1136/ard.2007.083360)

McKimmie, C. S. et al. (2008) Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. Journal of Immunology, 181(5), pp. 3353-3363.

Xu, D. et al. (2008) IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proceedings of the National Academy of Sciences of the United States of America, 105(31), pp. 10913-10918. (doi:10.1073/pnas.0801898105)

Grespan, R., Fukada, S. Y., Lemos, H. P., Vieira, S. M., Napimoga, M. H., Teixeira, M. M., Fraser, A. R. , Liew, F. Y., McInnes, I. B. , and Cunha, F. Q. (2008) CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis. Arthritis and Rheumatism, 58(7), pp. 2030-2040. (doi:10.1002/art.23597)

Culshaw, S.E., Millington, O.R., Brewer, J.M., and McInnes, I. (2008) Murine neutrophils present class II restricted antigen. Immunology Letters, 118(1), pp. 49-54. (doi:10.1016/j.imlet.2008.02.008)

Miller, A. M., Xu, D., Asquith, D. L., Denby, L., Li, Y., Sattar, N., Baker, A. H., McInnes, I. B., and Liew, F. Y. (2008) IL-33 reduces the development of atherosclerosis. Journal of Experimental Medicine, 205(2), pp. 339-346. (doi:10.1084/jem.20071868 )

Brennan, F., and McInnes, I. (2008) Evidence that cytokines play a role in rheumatoid arthritis. Journal of Clinical Investigation, 118(11), pp. 3537-3545.

Harnett, M. et al. (2008) The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis. Annals of the Rheumatic Diseases, 67(4), pp. 518-523. (doi:10.1136/ard.2007.073502)

Hothersall, E. et al. (2008) Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma. Thorax, 63(12), pp. 1070-1075. (doi:10.1136/thx.2008.100198)

Hutchison, S., Choo-Kang, B.S.W., Bundick, R.V., Leishman, A.J., Brewer, J.M., McInnes, I., and Garside, P. (2008) Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clinical and Experimental Immunology, 151(1), pp. 114-122.

Wong, S., Macrae, V.E., Gracie, J.A., McInnes, I., Galea, P., Gardner-Medwin, J., and Ahmed, S.F. (2008) Inflammatory cytokines in juvenile idiopathic arthritis: Effects on physical growth and the insulin-like-growth factor axis. Growth Hormone and IGF Research, 18(5), pp. 369-378. (doi:10.1016/j.ghir.2008.01.006 )

Verri, W. A., Cunha, T. M., Ferreira, S. H., Wei, X. , Leung, B. P., Fraser, A., McInnes, I. B., Liew, F. Y., and Cunha, F. Q. (2007) IL-15 mediates antigen-induced neutrophil migration by triggering IL-18 production. European Journal of Immunology, 37(12), pp. 3373-3380. (doi:10.1002/eji.200737488)

Cai, B., Hueber, A. J., Leung, B. P., Liew, F. Y., McInnes, I. B., Niedbala, W., and Wei, X.-q. (2007) IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. European Journal of Immunology, 37(11), pp. 3021-3029. (doi:10.1002/eji.200737810)

Komai-Koma, M., Li, Y. , Liew, F. Y., McInnes, I. B., McKenzie, A. N. J., and Xu, D. (2007) IL-33 is a chemoattractant for human Th2 cells. European Journal of Immunology, 37(10), pp. 2779-2786. (doi:10.1002/eji.200737547)

Asquith, D., and McInnes, I. (2007) Emerging cytokine targets in rheumatoid arthritis. Current Opinion in Rheumatology, 19, pp. 246-251.

Boyle, D. et al. (2007) Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: Standardization and consistency across centers. Journal of Rheumatology, 34, pp. 620-622.

Capell, H. et al. (2007) Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to sulfasalazine: results from the double-blind placebo-controlled MASCOT study. Annals of the Rheumatic Diseases, 66, pp. 235-241. (doi:10.1136/ard.2006.057133)

Dunning, L., Elias-Jones, I., Ferrell, W., Gracie, J., Hembrough, T., Kelso, E., Lockhart, J., and McInnes, I. (2007) Expression and proinflammatory role of proteinase-activated receptor 2 in rheumatoid synovium - Ex vivo studies using a novel proteinase-activated receptor 2 antagonist. Arthritis and Rheumatism, 56, pp. 765-771. (doi:10.1002/art.22423)

Macrae, V., Wong, S., Smith, W., Gracie, A., McInnes, I., Galea, P., Gardner-Medwin, J., Farquharson, C., Ahmed, S., and Ahmed, S. (2007) Cytokine profiling and in vitro studies of murine bone growth using biological fluids from children with juvenile idiopathic arthritis. Clinical Endocrinology, 67, pp. 442-448. (doi:10.1111/j.1365-2265.2007.02908.x)

Maffia, P., Zinselmeyer, B.H., Ialenti, A., Kennedy, S., Baker, A.H., McInnes, I., Brewer, J.M., and Garside, P. (2007) Multiphoton microscopy for 3-dimensional Imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), E326-E328.

McInnes, I., and Schett, G. (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nature Reviews Immunology, 7, pp. 429-442. (doi:10.1038/nri2094)

Sattar, N., Crompton, P., Cherry, L., Kane, D., Lowe, G., and McInnes, I. (2007) Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis - A double-blind, placebo-controlled study. Arthritis and Rheumatism, 56, pp. 831-839. (doi:10.1002/art.22447)

Anderson, E., McGrath, M., McInnes, I., and Thalhamer, T. (2006) Interleukin-12 to interleukin 'infinity': the rationale for future therapeutic cytokine targeting. Springer Seminars in Immunopathology, 27, pp. 425-442. (doi:10.1007/s00281-006-0011-x)

Baeten, D., Bresnihan, B., De, K., De, R., Fitzgerald, O., Kruithof, E., McInnes, I., Tak, P., Vandooren, B., and Veys, E. (2006) Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis. Arthritis and Rheumatism, 54, pp. 1795-1804. (doi:10.1002/art.21914)

Baeten, D., Bresnihan, B., Fitzgerald, O., McInnes, I., Smith, M., Tak, P., Ulfgren, A., and Veale, D. (2006) Standardisation of synovial tissue infiltrate analysis: how far have we come? how much further do we need to go? Annals of the Rheumatic Diseases, 65, pp. 93-100. (doi:10.1136/ard.2005.036905)

Connell, L., and McInnes, I.B. (2006) New cytokine targets in inflammatory rheumatic diseases. Best Practice and Research: Clinical Rheumatology, 20, pp. 865-878. (doi:10.1016/j.berh.2006.05.011)

Fitzgerald, O., and McInnes, I. (2006) Spondyloarthropathy: disease at the crossroads of immunity. Best Practice and Research: Clinical Rheumatology, 20, pp. 949-967. (doi:10.1016/j.berh.2006.06.010)

Alvaro, J. et al. (2005) A multicentre, randomised, double blind, placebo controlled phase II study of subcutaneous interferon beta-1a in the treatment of patients with active rheumatoid arthritis. Annals of the Rheumatic Diseases, 64, pp. 64-69. (doi:10.1136/ard.2003.020347)

Baeten, D. et al. (2005) Synovial tissue analysis in clinical trials. Journal of Rheumatology, 32, pp. 2481-2484.

Baeten, D., Bresnihan, B., Gerlag, D., Haringman, J., Kraan, M., McInnes, I., Smeets, T., Tak, P., and Zwinderman, A. (2005) Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases, 64, pp. 834-838. (doi:10.1136/ard.2004.029751)

Baslund, B. et al. (2005) Targeting interleukin-15 in patients with rheumatoid arthritis - A proof-of-concept study. Arthritis and Rheumatism, 52, pp. 2686-2692. (doi:10.1002/art.21249)

Blackbourn, D., Gracie, J., McInnes, I., and Rezaee, S. (2005) Inhibition of neutrophil function by the Kaposi's sarcoma-associated herpesvirus vOX2 protein. AIDS, 19, pp. 1907-1910.

Chandler, D., Griffiths, C., Helliwell, P., Kyle, S., Lewis, J., McHugh, N., McInnes, I., Oliver, S., and Symmons, D. (2005) Guideline for anti-TNF-alpha therapy in psoriatic arthritis. Rheumatology, 44, pp. 390-397. (doi:10.1093/rheumatology/keh514)

Choo-Kang, B., Hutchison, S., Nickdel, M., Bundick, R., Leishman, A., Brewer, J., McInnes, I., and Garside, P. (2005) TNF-blocking therapies: an alternative mode of action? Trends in Immunology, 26, pp. 518-522. (doi:10.1016/j.it.2005.07.007)

Culshaw, S., Leung, B., Gracie, J., Campbell, C., Thomson, D., Gemmell, C., Liew, F., and McInnes, I. (2005) Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection. European Journal of Immunology, 35, pp. 1438-1444. (doi:10.1002/ejui.200425661)

Gracie, J. et al. (2005) Disease association of two distinct interleukin-18 promoter polymorphisms in Caucasian rheumatoid arthritis patients. Genes and Immunity, 6, pp. 211-216. (doi:10.1038/sj.gene.6364183)

Gracie, J., Liew, F., and McInnes, I. (2005) Interleukin-18: A therapeutic target in rheumatoid arthritis? Commentary. Arthritis Research and Therapy, 7, pp. 38-41.

Kane, D., Lockhart, J., Balint, P., Mann, C., Ferrell, W., and McInnes, I. (2005) Protective effect of sensory denervation in inflammatory arthritis (evidence of regulatory neuroimmune pathways in the arthritic joint). Annals of the Rheumatic Diseases, 64(2), pp. 325-327.

Liew, F., and McInnes, I. (2005) A fork in the pathway to inflammation and arthritis. Nature Medicine, 11(6), pp. 601-602.

Liew, F., and McInnes, I. (2005) Cytokine networks - towards new therapies for rheumatoid arthritis. Nature Clinical Practice Rheumatology, 1, pp. 31-39. (doi:10.1038/ncprheum0020)

McInnes, I. (2005) Rheumatoid arthritis: of therapies and strategies. Current Opinion in Rheumatology, 17(3), pp. 271-273.

McInnes, I., and Sattar, N. (2005) Vascular comorbidity in rheumatoid arthritis: potential mechanisms and solutions. Current Opinion in Rheumatology, 17, pp. 286-292.

McInnes, I.B., and Gracie, J.A. (2004) Targeting cytokines beyond tumor necrosis factor-alpha and interleukin-1 in rheumatoid arthritis. Current Rheumatology Reports, 6, pp. 336-342.

McInnes, I.B., and Gracie, J.A. (2004) Interleukin-15: a new cytokine target for the treatment of inflammatory diseases. Current Opinion in Pharmacology, 4(4), pp. 392-397. (doi:10.1016/j.coph.2004.04.003)

Leung, B.P., Xu, D., Culshaw, S., McInnes, I.B., and Liew, .Y. (2004) A novel therapy of murine collagen-induced arthritis with soluble T1/ST2. Journal of Immunology, 173(1), pp. 145-150.

Maffia, P., Brewer, J.M., Gracie, J.A., Ianaro, A., Leung, B.P., Mitchell, P.J., Smith, K., McInnes, I.B., and Garside, P. (2004) Inducing experimental arthritis and breaking self-tolerance to joint-specific antigens with trackable, ovalbumin-specific T cells. Journal of Immunology, 173(1), pp. 151-156.

Harnett, W., McInnes, I.B., and Harnett, M.M. (2004) ES-62, a filarial nematode-derived immunomodulator with anti-inflammatory potential. Immunology Letters, 94(1-2), pp. 27-33. (doi:10.1016/j.imlet.2004.04.008)

McCarey, D.W., McInnes, I.B., Madhok, R., Hampson, R., Scherbakov, O., Ford, I., Capell, H., and Sattar, N. (2004) Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial. Lancet, 363(9426), pp. 2015-2021. (doi:10.1016/S0140-6736(04)16449-0)

McKay, A., Leung, B.P., McInnes, I.B., Thomson, N.C., and Liew, F.Y. (2004) A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. Journal of Immunology, 172(5), pp. 2903-2908.

Wilson, R., Moor, J., Jenkins, C., Miller, H., Walker, J.J., McLean, M.A., Norman, J., and McInnes, I.B. (2004) Abnormal first trimester serum interleukin 18 levels are associated with a poor outcome in women with a history of recurrent miscarriage. American Journal of Reproductive Immunology, 51(2), pp. 156-159. (doi:10.1046/j.8755-8920.2003.00126.x)

Alessandri, C., Barone, F., Blades, M., Bombardieri, M., Conigliaro, P., McInnes, I., Pittoni, V., Pitzalis, C., Priori, R., and Valesini, G. (2004) Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjogren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Research and Therapy, 6, R447-R456. (doi:10.1186/ar1209)

Bombardieri, M., Barone, F., Pittoni, P., Alessandri, C., Conigliaro, P., Blades, M.C., Priori, R., McInnes, I.B., Valesini, G., and Pitzalis, C. (2004) Increased circulating levels and salivary gland expression of interleukin-18 in patients with Sjögren's syndrome: relationship with autoantibody production and lymphoid organization of the periductal inflammatory infiltrate. Arthritis Research and Therapy, 6, R447-R456. (doi:10.1186/ar1209)

Capell, H., Madhok, R., McCarey, D., McInnes, I., and Sattar, N. (2004) Statins and rheumatoid arthritis - Reply. Lancet, 364(9448), p. 1855.

Harnett, W., Harnett, M.M., Leung, B.P., Gracie, J., and McInnes, I.B. (2004) The anti-inflammatory potential of the filarial nematode secreted product, ES-62. Current Topics in Medicinal Chemistry, 4(5), pp. 553-559. (doi:10.2174/1568026043451212)

Sattar, N., McCarey, D.W., Capell, H., and McInnes, I.B. (2003) Explaining how "high-grade" systemic inflammation accelerates vascular risk in rheumatoid arthritis. Circulation, 108(24), pp. 2957-2963. (doi:10.1161/01.CIR.0000099844.31524.05)

McInnes, I.B., Gracie, J.A., Harnett, M., Harnett, W., and Liew, F.Y. (2003) New strategies to control inflammatory synovitis: interleukin 15 and beyond. Annals of the Rheumatic Diseases, 62(2), pp. 51-54. (doi:10.1136/ard.62.suppl_2.ii51)

McInnes, I.B., Leung, B.P., Harnett, M., Gracie, J.A., Liew, F., and Harnett, W. (2003) A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62. Journal of Immunology, 171(4), pp. 2127-2133.

Wilson, R., Moore, J., Jenkins, C., Miller, H., Maclean, M.A., McInnes, I.B., and Walker, J.J. (2003) Abnormal IL-2 receptor levels in non-pregnant women with a history of recurrent miscarriage. Human Reproduction, 18(7), pp. 1529-1530. (doi:10.1093/humrep/deg287)

Gracie, J.A., Robertson, S.E., and McInnes, I.B. (2003) Interleukin-18. Journal of Leukocyte Biology, 73(2), pp. 213-224. (doi:10.1189/jlb.0602313)

Campbell, C. et al. (2003) A novel anti-inflammatory role for simvastatin in inflammatory arthritis. Journal of Immunology, 170, pp. 1524-1530.

Gracie, J., Komai-Koma, M., Liew, F., McInnes, I., Thomson, N., Wei, X., and Xu, D. (2003) Chemoattraction of human T cells by IL-18. Journal of Immunology, 170, pp. 1084-1090.

McInnes, I.B. (2003) Leukotrienes, mast cells, and T cells. Arthritis Research and Therapy, 5(6), pp. 288-289. (doi:10.1186/ar1017)

Guillen, C., McInnes, I.B., Vaughan, D.M., Kommajosyula, S., Van Berkel, P.H.C.,, Leung, B.P., Aguila, A., and Brock, J.H. (2002) Enhanced Th1 response to Staphylococcus aureas infection in human lactoferrin-transgenic mice. Journal of Immunology, 168(8), pp. 3950-3957.

Balint, P., Kane, D., Hunter, J., McInnes, I., Field, M., and Sturrock, R. (2002) Ultrasound guided versus conventional joint and soft tissue fluid aspiration in rheumatology practice: A pilot study. Journal of Rheumatology, 29, pp. 2209-2213.

Balint, P., Kane, D., Wilson, H., McInnes, I., and Sturrock, R. (2002) Ultrasonography of entheseal insertions in the lower limb in spondyloarthropathy. Annals of the Rheumatic Diseases, 61, pp. 905-910.

Boumpas, D., Ikeuchi, H., Kaneko, Y., Kuroiwa, T., McInnes, I., Nojima, Y., Ota, F., Tanaka, T., Tsukada, Y., and Ueki, K. (2002) Human platelets stimulate mesangial cells to produce monocyte chemoattractant protein-1 via the CD40/CD40 ligand pathway and may amplify glomerular injury. Journal of the American Society of Nephrology, 13, pp. 2488-2496. (doi:10.1097/01.ASN.0000029588.07166.20)

Gracie, J., Leung, B., and McInnes, I. (2002) Novel pathways that regulate tumor necrosis factor-alpha production in rheumatoid arthritis. Current Opinion in Rheumatology, 14, pp. 270-275.

Leung, B., Conacher, M., Hunter, D., McInnes, I., Liew, F., and Brewer, J. (2002) A novel dendritic cell-induced model of erosive inflammatory arthritis: Distinct roles for dendritic cells in T cell activation and induction of local inflammation. Journal of Immunology, 169, pp. 7071-7077.

Liew, F., and McInnes, I. (2002) Role of interleukin 15 and interleukin 18 in inflammatory response. Annals of the Rheumatic Diseases, 61, pp. 100-102.

Liew, F., and McInnes, I. (2002) The role of innate mediators in inflammatory response. Molecular Immunology, 38, pp. 887-890.

Arthur, H., Leung, B., Liew, F., McInnes, I., and Wei, X. (2001) Reduced incidence and severity of collagen-induced arthritis in mice lacking IL-18. Journal of Immunology, 166, pp. 517-521.

Boumpas, D. et al. (2001) IL-10 improves skin disease and modulates endothelial activation and leukocyte effector function in patients with psoriatic arthritis. Journal of Immunology, 167, pp. 4075-4082.

Campbell, C., Canetti, C., Culshaw, S., Cunha, F., Gracie, J., Hunter, D., Leung, B., Liew, F., and McInnes, I. (2001) A role for IL-18 in neutrophil activation. Journal of Immunology, 167, pp. 2879-2886.

Capell, H., Hamilton, J., Madhok, R., Mcinnes, I., and Wilson, H. (2001) The hip or not. Journal of Rheumatology, 28(6), pp. 1398-1400.

Capell, H., Hamilton, J., Hunter, J., Madhok, R., McInnes, I., Porter, D., and Thomson, E. (2001) Comparative study of intramuscular gold and methotrexate in a rheumatoid arthritis population from a socially deprived area. Annals of the Rheumatic Diseases, 60(6), pp. 566-572.

Capell, H., Hamilton, J., Madhok, R., McInnes, I., and Wilson, H. (2001) TNF alpha blockade in rheumatoid arthritis - Time for caution or enthusiasm? Scottish Medical Journal, 46(3), pp. 67-70.

Esfandiari, E., McInnes, I., Lindop, G., Huang, F., Field, M., Komai-Koma, M., Wei, X., and Liew, F. (2001) A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. Journal of Immunology, 167, pp. 5338-5347.

Gao, B., Gracie, J., Guan, H., Leung, B., Liew, F., McInnes, I., Niedbala, W., Orchardson, M., Paterson, G., and Wei, X. (2001) The sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo. Journal of Immunology, 167, pp. 277-282.

McCarey, D., McInnes, I., and Sattar, N. (2001) The antiinflammatory effects of statins. New England Journal of Medicine, 345(16), pp. 1209-1210.

McInnes, I. (2001) Rheumatoid arthritis - From bench to bedside. Rheumatic Disease Clinics of North America, 27, pp. 373-387.

Leung, B., Liew, F., and McInnes, I. (2000) Cell-cell interactions in synovitis - Interactions between T lymphocytes and synovial cells. Arthritis Research, 2(5), pp. 374-378.

Conference Proceedings

Frleta, M., Rainey, A.-A., Gilchrist, D.S., Crawford, L., Baxter, D., Kurowska-Stolarska, M., and McInnes, I.B. (2013) Mir-27b as Biomarker and Regulator of IL-6R Pathway in Resistant Rheumatoid Arthritis Monocyte. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S1035.

Millar, N.L., Gilchrist, D.S., Kurowska-Stolarska, M., Murrell, G.A.C., and McInnes, I. B. (2013) The Interleukin 33/miR29 Axis Regulates Differential Collagen Production in Tendinopathy. In: EULAR 2013: Annual European Congress of Rheumatology, Madrid, Spain, 12-15 June 2013, p. 140.

Millar, N. L., Gilchrist, D. S., Kurowska-Stolarska, M., Murrell, G. A.C. , and McInnes, I. (2013) The Interleukin 33/miR29 Axis Regulates Differential Collagen Production in Tendinopathy. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S405.

Rainey, A.-A., Gilchrist, D. S., Tange, C. E., Frleta, M., Crawford, L., Baxter, D., McInnes, I. B., and Kurowska-Stolarska, M. (2013) Mir-125a: A novel regulator of IL-6 and TLR driven pathways in RA pathogenesis. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S404.

Tange, C. E., Alivernini, S., Gilchrist, D. S., Crawford, L., Rainey, A.-A., Baxter, D., McInnes, I. B., and Kurowska-Stolarska, M. (2013) Mir-34a in Rheumatoid Arthritis: characterisation of elevated synovial expression and association with treatment resistance. In: 77th Annual Meeting of the American College of Rheumatology / 48th Annual Meeting of the Association of Rheumatology Health Professionals, San Diego, CA, 26-30 Oct 2013., S403.

Statache, G., Rainey, A.-A., Masters, S., Balanescu, A., McInnes, I. B., and Kurowska-Stolarska, M. (2012) Regulation of microrna 223 expression in a gouty arthritis. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Washington DC, USA, 9-14 Nov 2012, S811. (doi:10.1002/art.37735)

Elmesmari, A., Gilchrist, D., Fraser, A., Brewer, J., McInnes, I., and Kurowska-Stolarska, M. (2012) The role of miR-155 in monocyte migration in Rheumatoid arthritis. In: European Congress of Immunology, Glasgow, UK, 5-8 Sept 2012, pp. 588-589. (doi:10.1111/imm.12002)

Elmesmari, A., Pushparaj, P., Reilly, J., Kerr, S., Kurowska-Stolarska, M., and McInnes, I. (2012) The role of SPHKs and SIPRs in rheumatoid arthritis. In: European Congress of Immunology, Glasgow, UK, 5-8 Sept 2012, p. 260. (doi:10.1111/imm.12002)

Statache, G., Rainey, A., Crawford, L., Masters, S., Balanescu, A., McInnes, I., and Kurowska-Stolarska, M. (2012) Regulation of microRNA 223 expression in a gouty arthritis. In: European Congress of Immunology, Glasgow, UK, 5-8 Sept 2012, p. 227. (doi:10.1111/imm.12002)

Elmesmari, A., Gilchrist, D. S., Fraser, A. D., Vaughan, D., McQueenie, R., Graham, G., Brewer, J., McInnes, I. B., and Kurowska-Stolarska, M. (2012) Microrna-155 regulates chemokines and chemokine receptors in Rheumatoid Arthritis monocyte. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Washington DC, USA, 9-14 Nov 2012, S384. (doi:10.1002/art.37735)

Kurowska-Stolarska, M., Hasoo, M., Gilchrist, D. G., Ruzicska, E., Asquith, D., Welsh, D., Crawford, L., Hirani, N., McInnes, I. B., and McSharry, C. (2012) Microrna-155 protects against pulmonary fibrosis by targeting the transcription regulator LXR alpha. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Washington DC, USA, 9-14 Nov 2012, S386. (doi:10.1002/art.37735)

Alivernini, S. et al. (2011) The role of microRNA-34 and microRNA-22 in dendritic cells and monocyte activation in rheumatoid arthritis. In: American College of Rheumatology & Association of Rheumatology Health Professionals, Annual Scientific Meeting, Chicago, IL USA, 4-9 Nov 2011, S654.

Grassia, G., Dever, G., Gordon, P., McInnes, I., Spanbroek, R., Habenicht, A.J.R., Brewer, J., Garside, P., and Maffia, P. (2010) Real time imaging of lymphocytes in APOE-/- mouse aortic tertiary lymphoid organs. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2010, Manchester, UK, 07-08 June 2010, e12. (doi:10.1136/hrt.2010.205781.11)

Kurowska-Stolarska, M., Ballantine, L., Stolarski, B., Hunter, J., Hueber, A., Gracie, J.A., Liew, F. Y., and McInnes, I. B. (2010) miR-155 and miR-34a regulate proinflammatory cytokine production by human monocytes. In: European Workshop for Rheumatology Research, Bamberg, Germany, 4-7 Mar 2010, A30-A30. (doi:10.1136/ard.2010.129619g)

Dever, G., Rodolico, G., Berrino, L., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Three dimensional imaging of atherosclerotic plaques in apolipoprotien e-deficient mice. In: Spring Meeting of the British-Society-for-Cardiovascular-Research 2009, Oxford, Uk, 02-04 Apr 2009, (doi:10.1136/hrt.2009.178137i)

Dever, G., Rodolico , G., Liberato, B., McInnes, I., Brewer, J., Garside, P., and Maffia, P. (2009) Confocal and multiphoton laser scanning microscopy provide 3-dimensional imaging of atherosclerotic plaques in apolipoprotein E-deficient mice. In: Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2009, Washington DC, USA, 29 Apr - 1 May 2009, e74. (doi:10.1161/ATV.0B013E3181AB66E7)

Kurowska-Stolarska, M. S., Kewin, P., Stolarski, B., Fraser, A., Xu, D., McInnes, I., and Liew, F. Y. (2008) A role of IL-33 in bone turnover. In: 72nd Annual Scientific Meeting of the American College of Rheumatology and the 43rd Annual Scientific Meeting of the Association of Rheumatology Health Professionals, San Francisco CA, USA, 24-29 Oct 2008, S895.

This list was generated on Fri Apr 24 18:26:25 2015 BST.