Dr Stefan Siebert

  • Clinical Senior Lecturer in Inflammation and Rheumatology (Immunology)

telephone: 01413303375
email: Stefan.Siebert@glasgow.ac.uk

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • ScOttish Psoriatic artHritis Observational Study(SOPHOS)
    Scottish Executive Health Department
    2017 - 2020
     
  • Is interleukin-37a important in the pathology and treatment of inflammatory arthritis?
    Arthritis Research UK
    2017 - 2019
     
  • Spondyloarthritis research fellowship
    British Society for SpondyloArthritis
    2016 - 2019
     
  • Interactions between the Microbiome, Genome and Immunophenotype in Psoriatoc Arthritis
    Arthritis Research UK
    2016 - 2018
     
  • Stability of polyomic signatures in RA to facilitate transition to clinical practice - STABILITY-RA
    Scottish Executive Health Department
    2015 - 2017
     
  • WEB-based Physiotherapy for people with Axial Spondyloarthritis (WEB-PASS) - a cohort Study
    Arthritis Research UK
    2015 - 2017
     
  • Exploring the links between the intestinal inflammation and ankylosing spondylitis
    Arthritis Research UK
    2015 - 2018
     
  • Identification of disease-associated pathways induced in Psoriatic Arthritis synovial fibroblasts by biomechanical stress (ISSF Catalyst)
    Wellcome Trust
    2014 - 2015
     
  • MICA: Targeting the RA synovial fibroblast via cyclin dependent kinase inhibition - a phase IIa study
    Medical Research Council
    2014 - 2017
     
  • Comparing the immunophenotype of common inflammatory diseases to understand their pathogenesis.
    Scottish Executive Health Department
    2013 - 2015
     
  • Urine proteomics as biomarker for inflammatory arthritis
    Pfizer Global Research and Development
    2013 - 2014
     

Publications

List by: Type | Date

Jump to: 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2010 | 2008 | 2007 | 2005 | 2004
Number of items: 36.

2017

Packham, J. C. et al. (2017) A new era for collaboration? Rheumatology, (doi:10.1093/rheumatology/kex083) (PMID:28407115) (Early Online Publication)

McInnes, I. B. , Porter, D. and Siebert, S. (2017) Choosing new targets for rheumatoid arthritis therapeutics - too interesting to fail? Arthritis and Rheumatology, (doi:10.1002/art.40082) (PMID:28245351) (Early Online Publication)

Hamilton, L. et al. (2017) BSR and BHPR guideline for the treatment of axial spondyloarthritis (including ankylosing spondylitis) with biologics. Rheumatology, 56(2), pp. 313-316. (doi:10.1093/rheumatology/kew223) (PMID:27558584)

Siebert, S. , Porter, D., Paterson, C., Hampson, R., Gaya, D., Latosinska, A., Mischak, H., Schanstra, J., Mullen, W. and McInnes, I. (2017) Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups. Scientific Reports, 7, 40473. (doi:10.1038/srep40473) (PMID:28091549) (PMCID:PMC5320079)

2016

Pollock, J., Raza, K., Pratt, A. G., Hanson, H., Siebert, S. , Filer, A., Isaacs, J. D., Buckley, C. D., McInnes, I. B. and Falahee, M. (2016) Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research. Musculoskeletal Care, (doi:10.1002/msc.1171) (PMID:27982541) (Early Online Publication)

, Siebert, S. , Sengupta, R. and Tsoukas, A., (Eds.) (2016) Axial Spondyloarthritis. Series: Oxford rheumatology library. Oxford University Press. ISBN 9780198755296

Paul, L., Coulter, E.H., Cameron, S., McDonald, M.T., Brandon, M., Cook, D., McConnachie, A. and Siebert, S. (2016) Web-based physiotherapy for people with axial spondyloarthritis (WEBPASS) – a study protocol. BMC Musculoskeletal Disorders, 17, 360. (doi:10.1186/s12891-016-1218-1) (PMID:27553492) (PMCID:PMC4995794)

Kronisch, C. et al. (2016) Brief report: predicting functional disability: one-year results from the Scottish Early Rheumatoid Arthritis inception cohort. Arthritis and Rheumatology, 68(7), pp. 1596-1602. (doi:10.1002/art.39627) (PMID:26866516)

Zhou, S. et al. (2016) Defining disease phenotypes in primary care electronic health records by a machine learning approach: a case study in identifying rheumatoid arthritis. PLoS ONE, 11(5), e0154515. (doi:10.1371/journal.pone.0154515) (PMID:27135409) (PMCID:PMC4852928)

Wright, P. B., McEntegart, A., McCarey, D., McInnes, I. B. , Siebert, S. and Milling, S. W. F. (2016) Ankylosing Spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation. Rheumatology, 55(1), pp. 120-132. (doi:10.1093/rheumatology/kev245) (PMID:26320138) (PMCID:PMC4676904)

Fragoulis, G. E., Siebert, S. and McInnes, I. B. (2016) Therapeutic targeting of IL-17 and IL-23 cytokines in immune-mediated diseases. Annual Review of Medicine, 67(1), pp. 337-353. (doi:10.1146/annurev-med-051914-021944) (PMID:26565676)

Siebert, S. , Lyall, D. M., Mackay, D. F., Porter, D. and McInnes, I. B. (2016) Characteristics of rheumatoid arthritis and its association with major comorbid conditions: cross-sectional study of 502 649 UK Biobank participants. RMD Open, 2(1), e000267. (doi:10.1136/rmdopen-2016-000267) (PMID:27403335) (PMCID:PMC4932291)

2015

Wailoo, A., Hernández, M., Philips, C., Brophy, S. and Siebert, S. (2015) Modeling health state utility values in Ankylosing Spondylitis: comparisons of direct and indirect methods. Value in Health, 18(4), pp. 425-431. (doi:10.1016/j.jval.2015.02.016) (PMID:26091596)

Siebert, S. , Tsoukas, A., Robertson, J. and McInnes, I. (2015) Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases. Pharmacological Reviews, 67(2), pp. 280-309. (doi:10.1124/pr.114.009639) (PMID:25697599)

Cooksey, R., Brophy, S., Dennis, M., Davies, H., Atkinson, M., Irvine, E. and Siebert, S. (2015) Severe flare as a predictor of poor outcome in ankylosing spondylitis: a cohort study using questionnaire and routine data linkage. Rheumatology, 54(9), pp. 1563-1572. (doi:10.1093/rheumatology/kev015) (PMID:25802399)

Cooksey, R., Husain, M. J., Brophy, S., Davies, H., Rahman, M. A., Atkinson, M. D., Phillips, C. J. and Siebert, S. (2015) The cost of ankylosing spondylitis in the UK using linked routine and patient-reported survey data. PLoS ONE, 10(7), e0126105. (doi:10.1371/journal.pone.0126105) (PMID:26185984) (PMCID:PMC4506082)

2014

McInnes, I. B. and Siebert, S. (2014) Psoriatic arthritis - expanding options, exciting times? Acta Reumatologica Portuguesa, 39(4), pp. 294-295.

Patterson, H., Nibbs, R., McInnes, I. and Siebert, S. (2014) Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases. Clinical and Experimental Immunology, 176(1), pp. 1-10. (doi:10.1111/cei.12248)

Frleta, M., Siebert, S. and McInnes, I. B. (2014) The interleukin-17 pathway in psoriasis and psoriatic arthritis: disease pathogenesis and possibilities of treatment. Current Rheumatology Reports, 16(414), (doi:10.1007/s11926-014-0414-y) (PMID:24570394)

Orbai, A.-M. et al. (2014) Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis. Journal of Rheumatology, 41(11), pp. 2290-2294. (doi:10.3899/jrheum.140878)

2013

Brophy, S., Cooksey, R., Davies, H., Dennis, M.H., Zhou, S.M. and Siebert, S. (2013) The effect of physical activity and motivation on function in ankylosing spondylitis: a cohort study. Seminars in Arthritis and Rheumatism, 42(6), pp. 619-626. (doi:10.1016/j.semarthrit.2012.09.007)

Brophy, S., Davies, H., Dennis, M.S., Cooksey, R., Husain, M.J., Irvine, E. and Siebert, S. (2013) Fatigue in ankylosing spondylitis: treatment should focus on pain management. Seminars in Arthritis and Rheumatism, 42(4), pp. 361-367. (doi:10.1016/j.semarthrit.2012.06.002)

Davies, H., Brophy, S., Dennis, M., Cooksey, R., Irvine, E. and Siebert, S. (2013) Patient perspectives of managing fatigue in ankylosing spondylitis, and views on potential interventions: a qualitative study. BMC Musculoskeletal Disorders, 14(163), (doi:10.1186/1471-2474-14-163)

Evans, B.A. et al. (2013) Involving service users in trials: developing a standard operating procedure. Trials, 14(219), (doi:10.1186/1745-6215-14-219)

Nijjar, J., Tindell, A., McInnes, I.B. and Siebert, S. (2013) Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis. Rheumatology, 52(9), pp. 1556-1562. (doi:10.1093/rheumatology/ket225) (PMID:23861534)

Rapport, F. et al. (2013) Qualitative research within trials: developing a standard operating procedure for a clinical trials unit. Trials, 14(54), (doi:10.1186/1745-6215-14-54)

2012

Brophy, S., Cooksey, R., Atkinson, M., Zhou, S., Husain, M.J., Macey, S., Rahman, M.A. and Siebert, S. (2012) No increased rate of acute myocardial infarction or stroke among patients with ankylosing spondylitis—a retrospective cohort study using routine data. Seminars in Arthritis and Rheumatism, 42(2), pp. 140-145. (doi:10.1016/j.semarthrit.2012.02.008)

Cooksey, R., Brophy, S., Husain, M.J., Irvine, E., Davies, H. and Siebert, S. (2012) The information needs of people living with ankylosing spondylitis: a questionnaire survey. BMC Musculoskeletal Disorders, 13(243), (doi:10.1186/1471-2474-13-243)

Husain, M.J., Brophy, S., Macey, S., Pinder, L.M., Atkinson, M.D., Cooksey, R., Phillips, C.J. and Siebert, S. (2012) HERALD (Health Economics using Routine Anonymised Linked Data). BMC Medical Informatics and Decision Making, 12(1), p. 24. (doi:10.1186/1472-6947-12-24)

2010

Atkinson, M. D., Brophy, S., Siebert, S. , Gravenor, M. B., Phillips, C. J., Ford, D. V., Jones, K. H. and Lyons, R. A. (2010) Protocol for a population-based Ankylosing Spondylitis (PAS) cohort in Wales. BMC Musculoskeletal Disorders, 11(1), 197. (doi:10.1186/1471-2474-11-197) (PMID:20809952) (PMCID:PMC2941484)

Cooksey, R., Brophy, S., Gravenor, M.B., Brooks, C.J., Burrows, C.L. and Siebert, S. (2010) Frequency and characteristics of disease flares in ankylosing spondylitis. Rheumatology, 49(5), pp. 929-932. (doi:10.1093/rheumatology/kep435)

2008

Brophy, S., Burrows, C.L., Brooks, C., Gravenor, M.B., Siebert, S. and Allen, S.J. (2008) Internet-based randomised controlled trials for the evaluation of complementary and alternative medicines: probiotics in spondyloarthropathy. BMC Musculoskeletal Disorders, 9(1), p. 4. (doi:10.1186/1471-2474-9-4)

2007

Siebert, S. , Amos, N., Williams, B. D. and Lawson, T. M. (2007) Cytokine production by hepatic anaplastic large-cell lymphoma presenting as a rheumatic syndrome. Seminars in Arthritis and Rheumatism, 37(1), pp. 63-67. (doi:10.1016/j.semarthrit.2006.12.007) (PMID:17363040)

2005

Siebert, S. , Fielding, C. A., Williams, B. D. and Brennan, P. (2005) Mutation of the extracellular domain of tumour necrosis factor receptor 1 causes reduced NF-κB activation due to decreased surface expression. FEBS Letters, 579(23), pp. 5193-5198. (doi:10.1016/j.febslet.2005.08.037) (PMID:16162344)

Siebert, S. , Amos, N., Fielding, C. A., Wang, E. C. Y., Aksentijevich, I., Williams, B. D. and Brennan, P. (2005) Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant. Arthritis and Rheumatism, 52(4), pp. 1287-1292. (doi:10.1002/art.20955) (PMID:15818692) (PMCID:PMC2842000)

2004

Fielding, C. A., Siebert, S. , Rowe, M. and Brennan, P. (2004) Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression. FEBS Letters, 570(1-3), pp. 138-142. (doi:10.1016/j.febslet.2004.06.035) (PMID:15251454)

This list was generated on Thu May 25 05:32:08 2017 BST.
Number of items: 36.

Articles

Packham, J. C. et al. (2017) A new era for collaboration? Rheumatology, (doi:10.1093/rheumatology/kex083) (PMID:28407115) (Early Online Publication)

McInnes, I. B. , Porter, D. and Siebert, S. (2017) Choosing new targets for rheumatoid arthritis therapeutics - too interesting to fail? Arthritis and Rheumatology, (doi:10.1002/art.40082) (PMID:28245351) (Early Online Publication)

Hamilton, L. et al. (2017) BSR and BHPR guideline for the treatment of axial spondyloarthritis (including ankylosing spondylitis) with biologics. Rheumatology, 56(2), pp. 313-316. (doi:10.1093/rheumatology/kew223) (PMID:27558584)

Siebert, S. , Porter, D., Paterson, C., Hampson, R., Gaya, D., Latosinska, A., Mischak, H., Schanstra, J., Mullen, W. and McInnes, I. (2017) Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups. Scientific Reports, 7, 40473. (doi:10.1038/srep40473) (PMID:28091549) (PMCID:PMC5320079)

Pollock, J., Raza, K., Pratt, A. G., Hanson, H., Siebert, S. , Filer, A., Isaacs, J. D., Buckley, C. D., McInnes, I. B. and Falahee, M. (2016) Patient and researcher perspectives on facilitating patient and public involvement in rheumatology research. Musculoskeletal Care, (doi:10.1002/msc.1171) (PMID:27982541) (Early Online Publication)

Paul, L., Coulter, E.H., Cameron, S., McDonald, M.T., Brandon, M., Cook, D., McConnachie, A. and Siebert, S. (2016) Web-based physiotherapy for people with axial spondyloarthritis (WEBPASS) – a study protocol. BMC Musculoskeletal Disorders, 17, 360. (doi:10.1186/s12891-016-1218-1) (PMID:27553492) (PMCID:PMC4995794)

Kronisch, C. et al. (2016) Brief report: predicting functional disability: one-year results from the Scottish Early Rheumatoid Arthritis inception cohort. Arthritis and Rheumatology, 68(7), pp. 1596-1602. (doi:10.1002/art.39627) (PMID:26866516)

Zhou, S. et al. (2016) Defining disease phenotypes in primary care electronic health records by a machine learning approach: a case study in identifying rheumatoid arthritis. PLoS ONE, 11(5), e0154515. (doi:10.1371/journal.pone.0154515) (PMID:27135409) (PMCID:PMC4852928)

Wright, P. B., McEntegart, A., McCarey, D., McInnes, I. B. , Siebert, S. and Milling, S. W. F. (2016) Ankylosing Spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation. Rheumatology, 55(1), pp. 120-132. (doi:10.1093/rheumatology/kev245) (PMID:26320138) (PMCID:PMC4676904)

Fragoulis, G. E., Siebert, S. and McInnes, I. B. (2016) Therapeutic targeting of IL-17 and IL-23 cytokines in immune-mediated diseases. Annual Review of Medicine, 67(1), pp. 337-353. (doi:10.1146/annurev-med-051914-021944) (PMID:26565676)

Siebert, S. , Lyall, D. M., Mackay, D. F., Porter, D. and McInnes, I. B. (2016) Characteristics of rheumatoid arthritis and its association with major comorbid conditions: cross-sectional study of 502 649 UK Biobank participants. RMD Open, 2(1), e000267. (doi:10.1136/rmdopen-2016-000267) (PMID:27403335) (PMCID:PMC4932291)

Wailoo, A., Hernández, M., Philips, C., Brophy, S. and Siebert, S. (2015) Modeling health state utility values in Ankylosing Spondylitis: comparisons of direct and indirect methods. Value in Health, 18(4), pp. 425-431. (doi:10.1016/j.jval.2015.02.016) (PMID:26091596)

Siebert, S. , Tsoukas, A., Robertson, J. and McInnes, I. (2015) Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases. Pharmacological Reviews, 67(2), pp. 280-309. (doi:10.1124/pr.114.009639) (PMID:25697599)

Cooksey, R., Brophy, S., Dennis, M., Davies, H., Atkinson, M., Irvine, E. and Siebert, S. (2015) Severe flare as a predictor of poor outcome in ankylosing spondylitis: a cohort study using questionnaire and routine data linkage. Rheumatology, 54(9), pp. 1563-1572. (doi:10.1093/rheumatology/kev015) (PMID:25802399)

Cooksey, R., Husain, M. J., Brophy, S., Davies, H., Rahman, M. A., Atkinson, M. D., Phillips, C. J. and Siebert, S. (2015) The cost of ankylosing spondylitis in the UK using linked routine and patient-reported survey data. PLoS ONE, 10(7), e0126105. (doi:10.1371/journal.pone.0126105) (PMID:26185984) (PMCID:PMC4506082)

McInnes, I. B. and Siebert, S. (2014) Psoriatic arthritis - expanding options, exciting times? Acta Reumatologica Portuguesa, 39(4), pp. 294-295.

Patterson, H., Nibbs, R., McInnes, I. and Siebert, S. (2014) Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases. Clinical and Experimental Immunology, 176(1), pp. 1-10. (doi:10.1111/cei.12248)

Frleta, M., Siebert, S. and McInnes, I. B. (2014) The interleukin-17 pathway in psoriasis and psoriatic arthritis: disease pathogenesis and possibilities of treatment. Current Rheumatology Reports, 16(414), (doi:10.1007/s11926-014-0414-y) (PMID:24570394)

Orbai, A.-M. et al. (2014) Systematic review of treatment effectiveness and outcome measures for enthesitis in psoriatic arthritis. Journal of Rheumatology, 41(11), pp. 2290-2294. (doi:10.3899/jrheum.140878)

Brophy, S., Cooksey, R., Davies, H., Dennis, M.H., Zhou, S.M. and Siebert, S. (2013) The effect of physical activity and motivation on function in ankylosing spondylitis: a cohort study. Seminars in Arthritis and Rheumatism, 42(6), pp. 619-626. (doi:10.1016/j.semarthrit.2012.09.007)

Brophy, S., Davies, H., Dennis, M.S., Cooksey, R., Husain, M.J., Irvine, E. and Siebert, S. (2013) Fatigue in ankylosing spondylitis: treatment should focus on pain management. Seminars in Arthritis and Rheumatism, 42(4), pp. 361-367. (doi:10.1016/j.semarthrit.2012.06.002)

Davies, H., Brophy, S., Dennis, M., Cooksey, R., Irvine, E. and Siebert, S. (2013) Patient perspectives of managing fatigue in ankylosing spondylitis, and views on potential interventions: a qualitative study. BMC Musculoskeletal Disorders, 14(163), (doi:10.1186/1471-2474-14-163)

Evans, B.A. et al. (2013) Involving service users in trials: developing a standard operating procedure. Trials, 14(219), (doi:10.1186/1745-6215-14-219)

Nijjar, J., Tindell, A., McInnes, I.B. and Siebert, S. (2013) Inhibition of spleen tyrosine kinase in the treatment of rheumatoid arthritis. Rheumatology, 52(9), pp. 1556-1562. (doi:10.1093/rheumatology/ket225) (PMID:23861534)

Rapport, F. et al. (2013) Qualitative research within trials: developing a standard operating procedure for a clinical trials unit. Trials, 14(54), (doi:10.1186/1745-6215-14-54)

Brophy, S., Cooksey, R., Atkinson, M., Zhou, S., Husain, M.J., Macey, S., Rahman, M.A. and Siebert, S. (2012) No increased rate of acute myocardial infarction or stroke among patients with ankylosing spondylitis—a retrospective cohort study using routine data. Seminars in Arthritis and Rheumatism, 42(2), pp. 140-145. (doi:10.1016/j.semarthrit.2012.02.008)

Cooksey, R., Brophy, S., Husain, M.J., Irvine, E., Davies, H. and Siebert, S. (2012) The information needs of people living with ankylosing spondylitis: a questionnaire survey. BMC Musculoskeletal Disorders, 13(243), (doi:10.1186/1471-2474-13-243)

Husain, M.J., Brophy, S., Macey, S., Pinder, L.M., Atkinson, M.D., Cooksey, R., Phillips, C.J. and Siebert, S. (2012) HERALD (Health Economics using Routine Anonymised Linked Data). BMC Medical Informatics and Decision Making, 12(1), p. 24. (doi:10.1186/1472-6947-12-24)

Atkinson, M. D., Brophy, S., Siebert, S. , Gravenor, M. B., Phillips, C. J., Ford, D. V., Jones, K. H. and Lyons, R. A. (2010) Protocol for a population-based Ankylosing Spondylitis (PAS) cohort in Wales. BMC Musculoskeletal Disorders, 11(1), 197. (doi:10.1186/1471-2474-11-197) (PMID:20809952) (PMCID:PMC2941484)

Cooksey, R., Brophy, S., Gravenor, M.B., Brooks, C.J., Burrows, C.L. and Siebert, S. (2010) Frequency and characteristics of disease flares in ankylosing spondylitis. Rheumatology, 49(5), pp. 929-932. (doi:10.1093/rheumatology/kep435)

Brophy, S., Burrows, C.L., Brooks, C., Gravenor, M.B., Siebert, S. and Allen, S.J. (2008) Internet-based randomised controlled trials for the evaluation of complementary and alternative medicines: probiotics in spondyloarthropathy. BMC Musculoskeletal Disorders, 9(1), p. 4. (doi:10.1186/1471-2474-9-4)

Siebert, S. , Amos, N., Williams, B. D. and Lawson, T. M. (2007) Cytokine production by hepatic anaplastic large-cell lymphoma presenting as a rheumatic syndrome. Seminars in Arthritis and Rheumatism, 37(1), pp. 63-67. (doi:10.1016/j.semarthrit.2006.12.007) (PMID:17363040)

Siebert, S. , Fielding, C. A., Williams, B. D. and Brennan, P. (2005) Mutation of the extracellular domain of tumour necrosis factor receptor 1 causes reduced NF-κB activation due to decreased surface expression. FEBS Letters, 579(23), pp. 5193-5198. (doi:10.1016/j.febslet.2005.08.037) (PMID:16162344)

Siebert, S. , Amos, N., Fielding, C. A., Wang, E. C. Y., Aksentijevich, I., Williams, B. D. and Brennan, P. (2005) Reduced tumor necrosis factor signaling in primary human fibroblasts containing a tumor necrosis factor receptor superfamily 1A mutant. Arthritis and Rheumatism, 52(4), pp. 1287-1292. (doi:10.1002/art.20955) (PMID:15818692) (PMCID:PMC2842000)

Fielding, C. A., Siebert, S. , Rowe, M. and Brennan, P. (2004) Analysis of human tumour necrosis factor receptor 1 dominant-negative mutants reveals a major region controlling cell surface expression. FEBS Letters, 570(1-3), pp. 138-142. (doi:10.1016/j.febslet.2004.06.035) (PMID:15251454)

Edited Books

, Siebert, S. , Sengupta, R. and Tsoukas, A., (Eds.) (2016) Axial Spondyloarthritis. Series: Oxford rheumatology library. Oxford University Press. ISBN 9780198755296

This list was generated on Thu May 25 05:32:08 2017 BST.