Dr Sheon Samji

  • Research Fellow (School of Cardiovascular & Metabolic Health)

Biography

Sheon Mary Samji is a Research Fellow at the School of Cardiovascular and Metabolic Health (SCMH) at the University of Glasgow, specializing in molecular biology with a focus on proteomics. With over 12 years of academic and research experience, her expertise spans protein mass spectrometry, cell and molecular biology, and biochemistry.

Her academic journey began with a BSc and MSc in Biotechnology from the University of Pune, India, followed by a PhD in Biochemical Sciences from CSIR-National Chemical Laboratory (India), where she investigated proteomic patterns in pre-eclampsia. Sheon joined University of Glasgow as Newton International Fellow in 2018 funded by the Academy of Medical Sciences and the Royal Society. Before her tenure in Glasgow, she worked as a scientist at Enzene Bioscience Ltd (India), managing teams to characterize therapeutic biosimilars and novel medicinal compounds.

Her research interests revolve around understanding the molecular mechanisms underlying cardiovascular and renal diseases. Her work focuses on uromodulin, a protein linked to salt-sensitive hypertension and kidney function, investigating its role in the regulation of cardiovascular health and its response to environmental factors like salt, pregnancy, diabetes, heart failure and hypertension. Beyond research, Dr. Samji is actively involved in mentoring PhD students and teaching courses on proteomics, and she plays a key role in promoting equality and mental health awareness within SCMH.

Research interests

Research Theme: Vascular Diseases and Comorbidities

Research groups

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2014 | 2013 | 2012
Number of items: 32.

2025

Parveen, Humaira, Boder, Philipp, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708, Van Agtmael, Tom ORCID logoORCID: https://orcid.org/0000-0003-4282-449X, Rampoldi, Luca, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 and Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020 (2025) Early renal response to long term salt loading: Mitochondrial dysfunction, ER stress and uromodulin accumulation in the kidney medulla. American Journal of Physiology: Renal Physiology, (Accepted for Publication)

Alves-Lopes, Rheure ORCID logoORCID: https://orcid.org/0000-0002-4885-6647, Neves, Karla B., Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708, Montezano, Augusto C., Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 and Touyz, Rhian ORCID logoORCID: https://orcid.org/0000-0003-0670-0887 (2025) Salt-induced vascular damage in hypertension involves redox activation of PARP/TRPM2 signalling and inflammasome assembly. American Journal of Hypertension, (doi: 10.1093/ajh/hpaf071) (PMID:40312994) (Accepted for Publication)

Kuo, C.-W. et al. (2025) Nanobody-thioesterase chimeras to specifically target protein palmitoylation. Nature Communications, 16(1), 1445. (doi: 10.1038/s41467-025-56716-x) (PMID:39920166) (PMCID:PMC11805987)

2024

Main, Alice, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Sin, Yuan Yan ORCID logoORCID: https://orcid.org/0000-0001-6537-5266, Wright, Tom A., Ling, Jiayue, Blair, Connor M., Smith, Godfrey L. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741, Fuller, Will ORCID logoORCID: https://orcid.org/0000-0002-5883-4433 and Baillie, George S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316 (2024) SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline. International Journal of Biochemistry and Cell Biology, 176, 106668. (doi: 10.1016/j.biocel.2024.106668) (PMID:39321569)

Zhou, Manshi, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612, Padmanabhan, Sandosh ORCID logoORCID: https://orcid.org/0000-0003-3869-5808, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID logoORCID: https://orcid.org/0000-0002-6323-124X and Dominiczak, Anna ORCID logoORCID: https://orcid.org/0000-0003-4913-3608 (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0) (PMID:39259220) (Early Online Publication)

Mary, S. et al. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6) (PMID:38236469) (Early Online Publication)

2023

de Beer, Dalene, MC. Mels, Catharina, Schutte, Aletta, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Mischak, Harald and Kruger, Ruan (2023) Urinary peptidomics and pulse wave velocity: The African-PREDICT study. Journal of Proteome Research, 22(10), pp. 3282-3289. (doi: 10.1021/acs.jproteome.3c00347) (PMID:37688558) (PMCID:PMC10563154)

Montezano, A. C. et al. (2023) SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication. Scientific Reports, 13, 14086. (doi: 10.1038/s41598-023-41115-3) (PMID:37640791) (PMCID:PMC10462711)

De Beer, Dalene, Mels, Catharina M.C., Schutte, Aletta E., Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Latosinska, Agnieszka, Mischak, Harald and Kruger, Ruan (2023) Identifying a urinary peptidomics profile for hypertension in young adults: the African-PREDICT study. Proteomics, 23(11), 2200444. (doi: 10.1002/pmic.202200444) (PMID:36943111)

de Beer, Dalene, Mels, Catharina M. C., Schutte, Aletta E., Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Mischak, Harald and Kruger, Ruan (2023) A urinary peptidomics approach for early stages of cardiovascular disease risk: the African-PREDICT study. Hypertension Research, 46(2), pp. 485-494. (doi: 10.1038/s41440-022-01097-7) (PMID:36396816)

2022

Chen, Jun Yu, Chew, Khai Syuen, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Bagordo, Domenico, Rossi, Gian Paolo, Touyz, Rhian M. ORCID logoORCID: https://orcid.org/0000-0003-0670-0887, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 and Rossitto, Giacomo (2022) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137(3), pp. 239-250. (doi: 10.1042/CS20220609) (PMID:36648486)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Padmanabhan, Sandosh ORCID logoORCID: https://orcid.org/0000-0003-3869-5808, McBride, Martin W. ORCID logoORCID: https://orcid.org/0000-0002-6323-124X, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 and Dominiczak, Anna F. ORCID logoORCID: https://orcid.org/0000-0003-4913-3608 (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888) (PMID:36378920) (PMCID:PMC9553220)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Rossitto, Giacomo and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2022) Pathophysiology of hypertension. In: Nadar, Sunil and Lip, Gregory (eds.) Hypertension. Series: Oxford cardiology library. Oxford University Press: Oxford, pp. 11-20. ISBN 9780198870678 (doi: 10.1093/med/9780198870678.003.0002)

Gao, X. et al. (2022) Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7. Cell Calcium, 106, 102639. (doi: 10.1016/j.ceca.2022.102639) (PMID:36027648)

2021

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Rossitto, Giacomo, Graham, Lesley ORCID logoORCID: https://orcid.org/0000-0002-3901-5213, Scott, Kayley, Flynn, Arun, Kipgen, David, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708 and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)

Boder, Philipp, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Mark, Patrick B. ORCID logoORCID: https://orcid.org/0000-0003-3387-2123, Leiper, James ORCID logoORCID: https://orcid.org/0000-0003-4656-519X, Dominiczak, Anna F. ORCID logoORCID: https://orcid.org/0000-0003-4913-3608, Padmanabhan, Sandosh ORCID logoORCID: https://orcid.org/0000-0003-3869-5808, Rampold, Luca and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2021) Mechanistic interactions of uromodulin with the thick ascending limb: perspectives in physiology and hypertension. Journal of Hypertension, 39(8), pp. 1490-1504. (doi: 10.1097/HJH.0000000000002861) (PMID:34187999) (PMCID:PMC7611110)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Small, Heather, Herse, Florian, Carrick, Emma, Flynn, Arun, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Dechend, Ralf and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2021) Pre-existing hypertension and pregnancy induced hypertension reveal molecular differences in placental proteome in rodents. Physiological Genomics, 53(6), pp. 259-268. (doi: 10.1152/physiolgenomics.00160.2020) (PMID:33969702)

Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)

2020

Rossitto, G. et al. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76(24), pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022) (PMID:33303070) (PMCID:PMC7724570)

Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)

Currie, Gemma ORCID logoORCID: https://orcid.org/0000-0002-0797-0224, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020 and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2020) Is there a role for proteomics in diabetic renal disease? NDT Plus, 35(7), pp. 1133-1135. (doi: 10.1093/ndt/gfz017) (PMID:32777079) (PMCID:PMC7417003)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Currie, Gemma ORCID logoORCID: https://orcid.org/0000-0002-0797-0224, Schutte, Aletta E. and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2020) Cardiovascular proteomics. In: Faintuch, Joel and Faintuch, Salomao (eds.) Precision Medicine for Investigators, Practitioners and Providers. Academic Press: London ; San Diego, CA, pp. 263-270. ISBN 9780128191781 (doi: 10.1016/b978-0-12-819178-1.00025-3)

2019

Small, Heather Y., McNeilly, Sarah, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Sheikh, Adam Marcus and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2019) Resistin mediates sex-dependent effects of perivascular adipose tissue on vascular function in the SHRSP. Scientific Reports, 9, 6897. (doi: 10.1038/s41598-019-43326-z) (PMID:31053755) (PMCID:PMC6499830)

2018

Currie, G. E. et al. (2018) Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria. Cardiovascular Diabetology, 17, 50. (doi: 10.1186/s12933-018-0697-9) (PMID:29625564) (PMCID:PMC5889591)

2017

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Kulkarni, Mahesh J., Mehendale, Savita S., Joshi, Sadhana R. and Giri, Ashok P. (2017) Differential accumulation of vimentin fragments in preeclamptic placenta. Cytoskeleton, 74(11), pp. 420-425. (doi: 10.1002/cm.21390) (PMID:28752964)

Bhat, Shweta, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Giri, Ashok P. and Kulkarni, Mahesh J. (2017) Advanced glycation end products (AGEs) in diabetic complications. In: Kartha, C.C., Ramachandran, Surya and Pillai, Radhakrishna M. (eds.) Mechanisms of Vascular Defects in Diabetes Mellitus. Series: Advances in biochemistry in health and disease (17). Springer: Cham, pp. 423-449. ISBN 9783319603230 (doi: 10.1007/978-3-319-60324-7_19)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Small, Heather Yvonne, Siwy, Justyna, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Giri, Ashok and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2017) Polymerization-incompetent uromodulin in the pregnant stroke-prone spontaneously hypertensive rat. Hypertension, 69(5), pp. 910-918. (doi: 10.1161/HYPERTENSIONAHA.116.08826) (PMID:28348009) (PMCID:PMC5389592)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Kulkarni, Mahesh J., Mehendale, Savita S., Joshi, Sadhana R. and Giri, Ashok P. (2017) Tubulointerstitial nephritis antigen-like 1 protein is downregulated in the placenta of pre-eclamptic women. Clinical Proteomics, 14, 8. (doi: 10.1186/s12014-017-9144-2) (PMID:28344540) (PMCID:PMC5361709)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Kulkarni, Mahesh J., Malakar, Dipankar, Joshi, Sadhana R., Mehendale, Savita S. and Giri, Ashok P. (2017) Placental proteomics provides insights into pathophysiology of pre-eclampsia and predicts possible markers in plasma. Journal of Proteome Research, 16(2), pp. 1050-1060. (doi: 10.1021/acs.jproteome.6b00955) (PMID:28030762)

2014

Bhat, Shweta, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Banarjee, Reema, Giri, Ashok P. and Kulkarni, Mahesh J. (2014) Immune response to chemically modified proteome. Proteomics Clinical Applications, 8(1-2), pp. 19-34. (doi: 10.1002/prca.201300068) (PMID:24375944)

2013

Kulkarni, Mahesh J., Korwar, Arvind M., Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Bhonsle, Hemangi S. and Giri, Ashok P. (2013) Glycated proteome: from reaction to intervention. Proteomics Clinical Applications, 7(1-2), pp. 155-170. (doi: 10.1002/prca.201200101) (PMID:23184864)

2012

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Patil, Gouri V., Kulkarni, Asmita V., Kulkarni, Mahesh J., Joshi, Sadhana R., Mehendale, Savita S. and Giri, Ashok P. (2012) Dynamic proteome in enigmatic preeclampsia: an account of molecular mechanisms and biomarker discovery. Proteomics Clinical Applications, 6(1-2), pp. 79-90. (doi: 10.1002/prca.201100089) (PMID:22447695)

This list was generated on Fri Jul 11 10:19:05 2025 BST.
Jump to: Articles | Book Sections
Number of items: 32.

Articles

Parveen, Humaira, Boder, Philipp, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708, Van Agtmael, Tom ORCID logoORCID: https://orcid.org/0000-0003-4282-449X, Rampoldi, Luca, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 and Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020 (2025) Early renal response to long term salt loading: Mitochondrial dysfunction, ER stress and uromodulin accumulation in the kidney medulla. American Journal of Physiology: Renal Physiology, (Accepted for Publication)

Alves-Lopes, Rheure ORCID logoORCID: https://orcid.org/0000-0002-4885-6647, Neves, Karla B., Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708, Montezano, Augusto C., Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 and Touyz, Rhian ORCID logoORCID: https://orcid.org/0000-0003-0670-0887 (2025) Salt-induced vascular damage in hypertension involves redox activation of PARP/TRPM2 signalling and inflammasome assembly. American Journal of Hypertension, (doi: 10.1093/ajh/hpaf071) (PMID:40312994) (Accepted for Publication)

Kuo, C.-W. et al. (2025) Nanobody-thioesterase chimeras to specifically target protein palmitoylation. Nature Communications, 16(1), 1445. (doi: 10.1038/s41467-025-56716-x) (PMID:39920166) (PMCID:PMC11805987)

Main, Alice, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Sin, Yuan Yan ORCID logoORCID: https://orcid.org/0000-0001-6537-5266, Wright, Tom A., Ling, Jiayue, Blair, Connor M., Smith, Godfrey L. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741, Fuller, Will ORCID logoORCID: https://orcid.org/0000-0002-5883-4433 and Baillie, George S. ORCID logoORCID: https://orcid.org/0000-0003-2469-6316 (2024) SUMOylation of cardiac myosin binding protein-C reduces its phosphorylation and results in impaired relaxation following treatment with isoprenaline. International Journal of Biochemistry and Cell Biology, 176, 106668. (doi: 10.1016/j.biocel.2024.106668) (PMID:39321569)

Zhou, Manshi, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612, Padmanabhan, Sandosh ORCID logoORCID: https://orcid.org/0000-0003-3869-5808, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708, McBride, Martin W. ORCID logoORCID: https://orcid.org/0000-0002-6323-124X and Dominiczak, Anna ORCID logoORCID: https://orcid.org/0000-0003-4913-3608 (2024) Insights into uromodulin and blood pressure. Current Hypertension Reports, (doi: 10.1007/s11906-024-01317-0) (PMID:39259220) (Early Online Publication)

Mary, S. et al. (2024) Pregnancy-associated changes in urinary uromodulin excretion in chronic hypertension. Journal of Nephrology, (doi: 10.1007/s40620-023-01830-6) (PMID:38236469) (Early Online Publication)

de Beer, Dalene, MC. Mels, Catharina, Schutte, Aletta, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Mischak, Harald and Kruger, Ruan (2023) Urinary peptidomics and pulse wave velocity: The African-PREDICT study. Journal of Proteome Research, 22(10), pp. 3282-3289. (doi: 10.1021/acs.jproteome.3c00347) (PMID:37688558) (PMCID:PMC10563154)

Montezano, A. C. et al. (2023) SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication. Scientific Reports, 13, 14086. (doi: 10.1038/s41598-023-41115-3) (PMID:37640791) (PMCID:PMC10462711)

De Beer, Dalene, Mels, Catharina M.C., Schutte, Aletta E., Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Latosinska, Agnieszka, Mischak, Harald and Kruger, Ruan (2023) Identifying a urinary peptidomics profile for hypertension in young adults: the African-PREDICT study. Proteomics, 23(11), 2200444. (doi: 10.1002/pmic.202200444) (PMID:36943111)

de Beer, Dalene, Mels, Catharina M. C., Schutte, Aletta E., Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Mischak, Harald and Kruger, Ruan (2023) A urinary peptidomics approach for early stages of cardiovascular disease risk: the African-PREDICT study. Hypertension Research, 46(2), pp. 485-494. (doi: 10.1038/s41440-022-01097-7) (PMID:36396816)

Chen, Jun Yu, Chew, Khai Syuen, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Bagordo, Domenico, Rossi, Gian Paolo, Touyz, Rhian M. ORCID logoORCID: https://orcid.org/0000-0003-0670-0887, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 and Rossitto, Giacomo (2022) Skin-specific mechanisms of body fluid regulation in hypertension. Clinical Science, 137(3), pp. 239-250. (doi: 10.1042/CS20220609) (PMID:36648486)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Padmanabhan, Sandosh ORCID logoORCID: https://orcid.org/0000-0003-3869-5808, McBride, Martin W. ORCID logoORCID: https://orcid.org/0000-0002-6323-124X, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708, Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 and Dominiczak, Anna F. ORCID logoORCID: https://orcid.org/0000-0003-4913-3608 (2022) The role of uromodulin in salt-sensitive hypertension. Hypertension, 79, pp. 2419-2429. (doi: 10.1161/HYPERTENSIONAHA.122.19888) (PMID:36378920) (PMCID:PMC9553220)

Gao, X. et al. (2022) Palmitoylation regulates cellular distribution of and transmembrane Ca flux through TrpM7. Cell Calcium, 106, 102639. (doi: 10.1016/j.ceca.2022.102639) (PMID:36027648)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Boder, Philipp, Rossitto, Giacomo, Graham, Lesley ORCID logoORCID: https://orcid.org/0000-0002-3901-5213, Scott, Kayley, Flynn, Arun, Kipgen, David, Graham, Delyth ORCID logoORCID: https://orcid.org/0000-0002-7328-4708 and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2021) Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats. Clinical Science, 135(24), pp. 2749-2761. (doi: 10.1042/CS20211017) (PMID:34870708) (PMCID:PMC8689196)

Boder, Philipp, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Mark, Patrick B. ORCID logoORCID: https://orcid.org/0000-0003-3387-2123, Leiper, James ORCID logoORCID: https://orcid.org/0000-0003-4656-519X, Dominiczak, Anna F. ORCID logoORCID: https://orcid.org/0000-0003-4913-3608, Padmanabhan, Sandosh ORCID logoORCID: https://orcid.org/0000-0003-3869-5808, Rampold, Luca and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2021) Mechanistic interactions of uromodulin with the thick ascending limb: perspectives in physiology and hypertension. Journal of Hypertension, 39(8), pp. 1490-1504. (doi: 10.1097/HJH.0000000000002861) (PMID:34187999) (PMCID:PMC7611110)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Small, Heather, Herse, Florian, Carrick, Emma, Flynn, Arun, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Dechend, Ralf and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2021) Pre-existing hypertension and pregnancy induced hypertension reveal molecular differences in placental proteome in rodents. Physiological Genomics, 53(6), pp. 259-268. (doi: 10.1152/physiolgenomics.00160.2020) (PMID:33969702)

Rossitto, G. et al. (2021) High sodium intake, glomerular hyperfiltration and protein catabolism in patients with essential hypertension. Cardiovascular Research, 117(5), pp. 1372-1381. (doi: 10.1093/cvr/cvaa205) (PMID:33053160) (PMCID:PMC8064429)

Rossitto, G. et al. (2020) Reduced lymphatic reserve in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 76(24), pp. 2817-2829. (doi: 10.1016/j.jacc.2020.10.022) (PMID:33303070) (PMCID:PMC7724570)

Rossitto, G. et al. (2020) Tissue sodium excess is not hypertonic and reflects extracellular volume expansion. Nature Communications, 11, 4222. (doi: 10.1038/s41467-020-17820-2) (PMID:32839436) (PMCID:PMC7445299)

Currie, Gemma ORCID logoORCID: https://orcid.org/0000-0002-0797-0224, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020 and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2020) Is there a role for proteomics in diabetic renal disease? NDT Plus, 35(7), pp. 1133-1135. (doi: 10.1093/ndt/gfz017) (PMID:32777079) (PMCID:PMC7417003)

Small, Heather Y., McNeilly, Sarah, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Sheikh, Adam Marcus and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2019) Resistin mediates sex-dependent effects of perivascular adipose tissue on vascular function in the SHRSP. Scientific Reports, 9, 6897. (doi: 10.1038/s41598-019-43326-z) (PMID:31053755) (PMCID:PMC6499830)

Currie, G. E. et al. (2018) Urinary proteomics for prediction of mortality in patients with type 2 diabetes and microalbuminuria. Cardiovascular Diabetology, 17, 50. (doi: 10.1186/s12933-018-0697-9) (PMID:29625564) (PMCID:PMC5889591)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Kulkarni, Mahesh J., Mehendale, Savita S., Joshi, Sadhana R. and Giri, Ashok P. (2017) Differential accumulation of vimentin fragments in preeclamptic placenta. Cytoskeleton, 74(11), pp. 420-425. (doi: 10.1002/cm.21390) (PMID:28752964)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Small, Heather Yvonne, Siwy, Justyna, Mullen, William ORCID logoORCID: https://orcid.org/0000-0002-5685-1563, Giri, Ashok and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2017) Polymerization-incompetent uromodulin in the pregnant stroke-prone spontaneously hypertensive rat. Hypertension, 69(5), pp. 910-918. (doi: 10.1161/HYPERTENSIONAHA.116.08826) (PMID:28348009) (PMCID:PMC5389592)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Kulkarni, Mahesh J., Mehendale, Savita S., Joshi, Sadhana R. and Giri, Ashok P. (2017) Tubulointerstitial nephritis antigen-like 1 protein is downregulated in the placenta of pre-eclamptic women. Clinical Proteomics, 14, 8. (doi: 10.1186/s12014-017-9144-2) (PMID:28344540) (PMCID:PMC5361709)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Kulkarni, Mahesh J., Malakar, Dipankar, Joshi, Sadhana R., Mehendale, Savita S. and Giri, Ashok P. (2017) Placental proteomics provides insights into pathophysiology of pre-eclampsia and predicts possible markers in plasma. Journal of Proteome Research, 16(2), pp. 1050-1060. (doi: 10.1021/acs.jproteome.6b00955) (PMID:28030762)

Bhat, Shweta, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Banarjee, Reema, Giri, Ashok P. and Kulkarni, Mahesh J. (2014) Immune response to chemically modified proteome. Proteomics Clinical Applications, 8(1-2), pp. 19-34. (doi: 10.1002/prca.201300068) (PMID:24375944)

Kulkarni, Mahesh J., Korwar, Arvind M., Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Bhonsle, Hemangi S. and Giri, Ashok P. (2013) Glycated proteome: from reaction to intervention. Proteomics Clinical Applications, 7(1-2), pp. 155-170. (doi: 10.1002/prca.201200101) (PMID:23184864)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Patil, Gouri V., Kulkarni, Asmita V., Kulkarni, Mahesh J., Joshi, Sadhana R., Mehendale, Savita S. and Giri, Ashok P. (2012) Dynamic proteome in enigmatic preeclampsia: an account of molecular mechanisms and biomarker discovery. Proteomics Clinical Applications, 6(1-2), pp. 79-90. (doi: 10.1002/prca.201100089) (PMID:22447695)

Book Sections

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Rossitto, Giacomo and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2022) Pathophysiology of hypertension. In: Nadar, Sunil and Lip, Gregory (eds.) Hypertension. Series: Oxford cardiology library. Oxford University Press: Oxford, pp. 11-20. ISBN 9780198870678 (doi: 10.1093/med/9780198870678.003.0002)

Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Currie, Gemma ORCID logoORCID: https://orcid.org/0000-0002-0797-0224, Schutte, Aletta E. and Delles, Christian ORCID logoORCID: https://orcid.org/0000-0003-2238-2612 (2020) Cardiovascular proteomics. In: Faintuch, Joel and Faintuch, Salomao (eds.) Precision Medicine for Investigators, Practitioners and Providers. Academic Press: London ; San Diego, CA, pp. 263-270. ISBN 9780128191781 (doi: 10.1016/b978-0-12-819178-1.00025-3)

Bhat, Shweta, Mary, Sheon ORCID logoORCID: https://orcid.org/0000-0001-9392-3020, Giri, Ashok P. and Kulkarni, Mahesh J. (2017) Advanced glycation end products (AGEs) in diabetic complications. In: Kartha, C.C., Ramachandran, Surya and Pillai, Radhakrishna M. (eds.) Mechanisms of Vascular Defects in Diabetes Mellitus. Series: Advances in biochemistry in health and disease (17). Springer: Cham, pp. 423-449. ISBN 9783319603230 (doi: 10.1007/978-3-319-60324-7_19)

This list was generated on Fri Jul 11 10:19:05 2025 BST.

Grants

Grants and Awards listed are those received whilst working with the University of Glasgow.

  • Mapping renal pathophysiology and cellular alterations in HFpEF at single-nuclei resolution. Exploring kidney changes in heart failure at single cell level.
    Tenovus Scotland
    2025 - 2027
     

Teaching

Sheon is on a research-only track, the majority of my teaching efforts involve mentoring PhD students, PGT, UGT and other junior colleagues. Apart from research focused teaching, she is involved in formal teaching and grading on L5- proteomics: clinical biomarker for Masters students (Biotechnology applications) for School of Molecular Biosciences.

Professional activities & recognition

Research fellowships

  • 2018 - 2020: Newton International Fellowship, The Royal Society
  • 2011 - 2016: CSIR research fellowship, Govt of India
  • 2015 - 2016: Commonwealth Split-Site Scholarship

Research datasets

Jump to: 2022
Number of items: 1.

2022

GAO, X., Samji, S. and Fuller, W. (2022) Proteomic analysis of TrpM7 interacting proteins in HEK cells. [Data Collection]

This list was generated on Fri Jul 11 10:19:07 2025 BST.

Dr Sheon Samji