2023

Suzuki, T. et al. (2023) beta-catenin drives butyrophilin-like molecule loss and gamma delta T cell exclusion in colon cancer. Cancer Immunology Research, (Accepted for Publication)

Coffelt, S. B. and Suzuki, T. (2023) γδ T cells turn the tables on immune-evasive colon cancer. Med, 4(3), pp. 141-142. (doi: 10.1016/j.medj.2023.02.007)

Edwards, S. C. et al. (2023) PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells. Journal of Experimental Medicine, 220(2), e20211431. (doi: 10.1084/jem.20211431) (PMID:36480166) (PMCID:PMC9732671)

2022

van Wagensveld, L. et al. (2022) Homologous recombination deficiency and cyclin E1 amplification are correlated with immune cell infiltration and survival in high-grade serous ovarian cancer. Cancers, 14(23), 5965. (doi: 10.3390/cancers14235965)

Paterson, K., Paterson, S., Mulholland, T., Coffelt, S.B. and Zagnoni, M. (2022) Assessment of CAR-T mediated and targeted cytotoxicity in 3D microfluidic TBNC co-culture models for combination therapy. IEEE Open Journal of Engineering in Medicine and Biology, 3, pp. 86-95. (doi: 10.1109/OJEMB.2022.3178302)

Lawrence, M., Wiesheu, R. and Coffelt, S. B. (2022) The duplexity of unconventional T cells in cancer. International Journal of Biochemistry and Cell Biology, 146, 106213. (doi: 10.1016/j.biocel.2022.106213) (PMID:35447350)

Curio, S. et al. (2022) NKG2D signaling regulates IL-17A-producing γδT cells in mice to promote cancer progression. Discovery Immunology, 1(1), kyac002. (doi: 10.1093/discim/kyac002) (PMID:36277678) (PMCID:PMC9580227)

2021

Johnson, S. A. et al. (2021) Monocytes mediate Salmonella Typhimurium-induced tumor growth inhibition in a mouse melanoma model. European Journal of Immunology, 51(12), pp. 3228-3238. (doi: 10.1002/eji.202048913) (PMID:34633664) (PMCID:PMC9214623)

Paterson, K., Zanivan, S. , Glasspool, R., Coffelt, S.B. and Zagnoni, M. (2021) Microfluidic technologies for immunotherapy studies on solid tumours. Lab on a Chip, 21(12), pp. 2306-2329. (doi: 10.1039/D0LC01305F) (PMID:34085677) (PMCID:PMC8204114)

McFarlane, A. J., Fercoq, F., Coffelt, S. B. and Carlin, L. M. (2021) Neutrophil dynamics in the tumor microenvironment. Journal of Clinical Investigation, 131(6), e143759. (doi: 10.1172/JCI143759) (PMID:33720040)

Edwards, S. C., Hoevenaar, W. H.M. and Coffelt, S. B. (2021) Emerging immunotherapies for metastasis. British Journal of Cancer, 124, pp. 37-48. (doi: 10.1038/s41416-020-01160-5) (PMID:33262520)

2020

Coffelt, S. B. , Kabelitz, D., Silva-Santos, B., Kuball, J., Born, W. and Bank, I. (2020) Editorial: γδ T Cells in Cancer. Frontiers in Immunology, 11, 602411. (doi: 10.3389/fimmu.2020.602411) (PMID:33329597) (PMCID:PMC7714948)

Suzuki, T., Hayman, L., Kilbey, A., Edwards, J. and Coffelt, S. B. (2020) Gut γδ T cells as guardians, disruptors and instigators of cancer. Immunological Reviews, 298(1), pp. 198-217. (doi: 10.1111/imr.12916) (PMID:32840001)

Millar, R., Kilbey, A., Remak, S.-J., Severson, T. M., Dhayade, S., Sandilands, E., Foster, K., Bryant, D. M. , Blyth, K. and Coffelt, S. B. (2020) The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer. Molecular Oncology, 14(8), pp. 1868-1880. (doi: 10.1002/1878-0261.12734) (PMID:32484599) (PMCID:PMC7400785)

Dhayade, S., Pietzke, M., Wiesheu, R., Tait-Mulder, J., Athineos, D., Sumpton, D., Coffelt, S. , Blyth, K. and Vazquez, A. (2020) Impact of formate supplementation on body weight and plasma amino acids. Nutrients, 12(8), 2181. (doi: 10.3390/nu12082181) (PMID:32708052) (PMCID:PMC7469024)

Muthalagu, N. et al. (2020) Repression of the type I interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in pancreatic ductal adenocarcinoma. Cancer Discovery, 10(6), pp. 872-887. (doi: 10.1158/2159-8290.CD-19-0620) (PMID:32200350) (PMCID:PMC7611248)

2019

Wellenstein, M. D. et al. (2019) Loss of p53 triggers Wnt-dependent systemic inflammation to drive breast cancer metastasis. Nature, 572, pp. 538-542. (doi: 10.1038/s41586-019-1450-6) (PMID:31367040) (PMCID:PMC6707815)

Mackey, J. B.G., Coffelt, S. B. and Carlin, L. M. (2019) Neutrophil maturity in cancer. Frontiers in Immunology, 10, 1912. (doi: 10.3389/fimmu.2019.01912) (PMID:31474989) (PMCID:PMC6702268)

Silva-Santos, B., Mensurado, S. and Coffelt, S. B. (2019) γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer. Nature Reviews Cancer, 19(7), pp. 392-404. (doi: 10.1038/s41568-019-0153-5) (PMID:31209264)

Salvagno, C. et al. (2019) Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response. Nature Cell Biology, 21(4), pp. 511-521. (doi: 10.1038/s41556-019-0298-1) (PMID:30886344) (PMCID:PMC6451630)

2018

Kruspig, B. et al. (2018) The ERBB network facilitates KRAS-driven lung tumorigenesis. Science Translational Medicine, 10(446), eaao2565. (doi: 10.1126/scitranslmed.aao2565) (PMID:29925636) (PMCID:PMC6881183)

2017

Rumney, R. M.H., Coffelt, S. B. , Neale, T. A., Dhayade, S., Tozer, G. M. and Miller, G. (2017) PyMT-Maclow: A novel, inducible, murine model for determining the role of CD68 positive cells in breast tumor development. PLoS ONE, 12(12), e0188591. (doi: 10.1371/journal.pone.0188591) (PMID:29220404) (PMCID:PMC5722323)

Walton, J. B. et al. (2017) CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity. Scientific Reports, 7, 16827. (doi: 10.1038/s41598-017-17119-1) (PMID:29203787) (PMCID:PMC5715106)

Carron, E. C., Homra, S., Rosenberg, J., Coffelt, S. B. , Kittrell, F., Zhang, Y., Creighton, C. J., Fuqua, S. A., Medina, D. and Machado, H. L. (2017) Macrophages promote the progression of premalignant mammary lesions to invasive cancer. Oncotarget, 8(31), pp. 50731-50746. (doi: 10.18632/oncotarget.14913) (PMID:28159924)

van Baal, J.O.A.M., Van de Vijver, K.K., Coffelt, S.B. , van der Noort, V., van Driel, W.J., Kenter, G.G., Buist, M.R. and Lok, C.A.R. (2017) Incidence of lymph node metastases in clinical early-stage mucinous and seromucinous ovarian carcinoma: a retrospective cohort study. BJOG: An International Journal of Obstetrics and Gynaecology, 124(3), pp. 486-494. (doi: 10.1111/1471-0528.14425) (PMID:27860146)

Kersten, K. et al. (2017) Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages. OncoImmunology, 6(8), e1334744. (doi: 10.1080/2162402X.2017.1334744) (PMID:28919995) (PMCID:PMC5593698)

2016

Coffelt, S. B. , Wellenstein, M. D. and de Visser, K. E. (2016) Neutrophils in cancer: neutral no more. Nature Reviews Cancer, 16(7), pp. 431-446. (doi: 10.1038/nrc.2016.52) (PMID:27282249)

Coffelt, S. B. and de Visser, K. E. (2016) Revving up dendritic cells while braking PD-L1 to jump-start the cancer-immunity cycle motor. Immunity, 44(4), pp. 722-724. (doi: 10.1016/j.immuni.2016.03.014) (PMID:27096314)

Coffelt, S. B. and de Visser, K. E. (2016) Systemic inflammation: Cancer's long-distance reach to maximize metastasis. OncoImmunology, 5(2), e1075694. (doi: 10.1080/2162402X.2015.1075694) (PMID:27057449) (PMCID:PMC4801429)

Rahat, M. A., Coffelt, S. , Granot, Z., Muthana, M. and Amedei, A. (2016) Macrophages and neutrophils: regulation of the inflammatory microenvironment in autoimmunity and cancer. Mediators of Inflammation, 2016, 5894347. (doi: 10.1155/2016/5894347) (PMID:27725789) (PMCID:PMC5048028)

2015

Doornebal, C. W., Vrijland, K., Hau, C.-S., Coffelt, S. B. , Ciampricotti, M., Jonkers, J., de Visser, K. E. and Hollmann, M. W. (2015) Morphine does not facilitate breast cancer progression in two preclinical mouse models for human invasive lobular and HER2+ breast cancer. Pain, 156(8), pp. 1424-1432. (doi: 10.1097/j.pain.0000000000000136) (PMID:25734987)

Coffelt, S. B. et al. (2015) IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis. Nature, 522(7556), pp. 345-348. (doi: 10.1038/nature14282) (PMID:25822788) (PMCID:PMC4475637)

Coffelt, S. B. and de Visser, K. E. (2015) Immune-mediated mechanisms influencing the efficacy of anticancer therapies. Trends in Immunology, 36(4), pp. 198-216. (doi: 10.1016/j.it.2015.02.006) (PMID:25857662)

2014

Al-ofi, E., Coffelt, S. B. and Anumba, D. O. (2014) Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients. Journal of Reproductive Immunology, 103, pp. 23-28. (doi: 10.1016/j.jri.2014.02.004) (PMID:24661950)

Coffelt, S. B. and de Visser, K. E. (2014) Cancer: Inflammation lights the way to metastasis. Nature, 507(7490), pp. 48-49. (doi: 10.1038/nature13062) (PMID:24572360)

2013

Gheryani, N., Coffelt, S. B. , Gartland, A., Rumney, R. M.H., Kiss-Toth, E., Lewis, C. E., Tozer, G. M., Greaves, D. R., Dear, T. N. and Miller, G. (2013) Generation of a novel mouse model for the inducible depletion of macrophages in vivo. genesis, 51(1), pp. 41-49. (doi: 10.1002/dvg.22343) (PMID:22927121)

2012

Al-Ofi, E., Anumba, D.O.C. and Coffelt, S. (2012) OS006. Functional expression of endogenous ligands of Toll like receptor4 on monocytes and placentae from women during normal pregnancy andpre-eclampsia. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2(3), p. 178. (doi: 10.1016/j.preghy.2012.04.008) (PMID:26105221)

Wu, W.K.K., Coffelt, S.B. , Cho, C.H., Wang, X.J., Lee, C.W., Chan, F.K.L., Yu, J. and Sung, J.J.Y. (2012) The autophagic paradox in cancer therapy. Oncogene, 31(8), pp. 939-953. (doi: 10.1038/onc.2011.295) (PMID:21765470)

2011

Coffelt, S. B. et al. (2011) Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion. Journal of Immunology, 186(7), pp. 4183-4190. (doi: 10.4049/​jimmunol.1002802) (PMID:21368233)

Welford, A. F. et al. (2011) TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice. Journal of Clinical Investigation, 121(5), pp. 1969-1973. (doi: 10.1172/JCI44562) (PMID:21490397) (PMCID:PMC3083764)

Muthana, M. et al. (2011) Use of macrophages to target therapeutic adenovirus to human prostate tumors. Cancer Research, 71(5), pp. 1805-1815. (doi: 10.1158/0008-5472.CAN-10-2349) (PMID:21233334)

2010

Coffelt, S. B. et al. (2010) Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions. Cancer Research, 70(13), pp. 5270-5280. (doi: 10.1158/0008-5472.CAN-10-0012) (PMID:20530679)

Wu, W. K.K., Wang, G., Coffelt, S. B. , Betancourt, A. M., Lee, C. W., Fan, D., Wu, K., Yu, J., Sung, J. J.Y. and Cho, C. H. (2010) Emerging roles of the host defense peptide LL-37 in human cancer and its potential therapeutic applications. International Journal of Cancer, 127(8), pp. 1741-1747. (doi: 10.1002/ijc.25489) (PMID:20521250) (PMCID:PMC2930073)

Coffelt, S. B. , Lewis, C. E., Naldini, L., Brown, J. M., Ferrara, N. and De Palma, M. (2010) Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors. American Journal of Pathology, 176(4), pp. 1564-1576. (doi: 10.2353/ajpath.2010.090786) (PMID:20167863) (PMCID:PMC2843445)

2009

Fang, H.-Y. et al. (2009) Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Blood, 114(4), pp. 844-859. (doi: 10.1182/blood-2008-12-195941) (PMID:19454749) (PMCID:PMC2882173)

Coffelt, S. B. , Tomchuck, S. L., Zwezdaryk, K. J., Danka, E. S. and Scandurro, A. B. (2009) Leucine leucine-37 uses formyl peptide receptor-like 1 to activate signal transduction pathways, stimulate oncogenic gene expression, and enhance the invasiveness of ovarian cancer cells. Molecular Cancer Research, 7(6), pp. 907-915. (doi: 10.1158/1541-7786.MCR-08-0326) (PMID:19491199) (PMCID:PMC2755540)

Coffelt, S. B. et al. (2009) The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells. Proceedings of the National Academy of Sciences of the United States of America, 106(10), pp. 3806-3811. (doi: 10.1073/pnas.0900244106) (PMID:19234121) (PMCID:PMC2656161)

2008

Coffelt, S. B. and Scandurro, A. B. (2008) Tumors sound the alarmin(s). Cancer Research, 68(16), pp. 6482-6485. (doi: 10.1158/0008-5472.CAN-08-0044) (PMID:18701469) (PMCID:PMC2755533)

Murdoch, C., Muthana, M., Coffelt, S. B. and Lewis, C. E. (2008) The role of myeloid cells in the promotion of tumour angiogenesis. Nature Reviews Cancer, 8(8), pp. 618-631. (doi: 10.1038/nrc2444) (PMID:18633355)

Xiang, S., Coffelt, S. B. , Mao, L., Yuan, L., Cheng, Q. and Hill, S. M. (2008) Period-2: a tumor suppressor gene in breast cancer. Journal of Circadian Rhythms, 6(1), p. 4. (doi: 10.1186/1740-3391-6-4) (PMID:18334030) (PMCID:PMC2365929)

Tomchuck, S. L., Zwezdaryk, K. J., Coffelt, S. B. , Waterman, R. S., Danka, E. S. and Scandurro, A. B. (2008) Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses. Stem Cells, 26(1), pp. 99-107. (doi: 10.1634/stemcells.2007-0563) (PMID:17916800) (PMCID:PMC2757778)

2007

Coffelt, S. B. , Waterman, R. S., Florez, L., Bentrup, K. H. z., Zwezdaryk, K. J., Tomchuck, S. L., LaMarca, H. L., Danka, E. S., Morris, C. A. and Scandurro, A. B. (2007) Ovarian cancers overexpress the antimicrobial protein hCAP-18 and its derivative LL-37 increases ovarian cancer cell proliferation and invasion. International Journal of Cancer, 122(5), pp. 1030-1039. (doi: 10.1002/ijc.23186) (PMID:17960624)

Zwezdaryk, K. J., Coffelt, S. B. , Figueroa, Y. G., Liu, J., Phinney, D. G., LaMarca, H. L., Florez, L., Morris, C. B., Hoyle, G. W. and Scandurro, A. B. (2007) Erythropoietin, a hypoxia-regulated factor, elicits a pro-angiogenic program in human mesenchymal stem cells. Experimental Hematology, 35(4), pp. 640-652. (doi: 10.1016/j.exphem.2007.01.044) (PMID:17379074)

Abboud, E. R., Coffelt, S. B. , Figueroa, Y. G., Zwezdaryk, K. J., Nelson, A. B., Sullivan, D. E., Morris, C. B., Tang, Y., Beckman, B. S. and Scandurro, A. B. (2007) Integrin-linked kinase: a hypoxia-induced anti-apoptotic factor exploited by cancer cells. International Journal of Oncology, 30(1), pp. 113-122. (doi: 10.3892/ijo.30.1.113) (PMID:17143519)

Articles

Suzuki, T. et al. (2023) beta-catenin drives butyrophilin-like molecule loss and gamma delta T cell exclusion in colon cancer. Cancer Immunology Research, (Accepted for Publication)

Coffelt, S. B. and Suzuki, T. (2023) γδ T cells turn the tables on immune-evasive colon cancer. Med, 4(3), pp. 141-142. (doi: 10.1016/j.medj.2023.02.007)

Edwards, S. C. et al. (2023) PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells. Journal of Experimental Medicine, 220(2), e20211431. (doi: 10.1084/jem.20211431) (PMID:36480166) (PMCID:PMC9732671)

van Wagensveld, L. et al. (2022) Homologous recombination deficiency and cyclin E1 amplification are correlated with immune cell infiltration and survival in high-grade serous ovarian cancer. Cancers, 14(23), 5965. (doi: 10.3390/cancers14235965)

Paterson, K., Paterson, S., Mulholland, T., Coffelt, S.B. and Zagnoni, M. (2022) Assessment of CAR-T mediated and targeted cytotoxicity in 3D microfluidic TBNC co-culture models for combination therapy. IEEE Open Journal of Engineering in Medicine and Biology, 3, pp. 86-95. (doi: 10.1109/OJEMB.2022.3178302)

Lawrence, M., Wiesheu, R. and Coffelt, S. B. (2022) The duplexity of unconventional T cells in cancer. International Journal of Biochemistry and Cell Biology, 146, 106213. (doi: 10.1016/j.biocel.2022.106213) (PMID:35447350)

Curio, S. et al. (2022) NKG2D signaling regulates IL-17A-producing γδT cells in mice to promote cancer progression. Discovery Immunology, 1(1), kyac002. (doi: 10.1093/discim/kyac002) (PMID:36277678) (PMCID:PMC9580227)

Johnson, S. A. et al. (2021) Monocytes mediate Salmonella Typhimurium-induced tumor growth inhibition in a mouse melanoma model. European Journal of Immunology, 51(12), pp. 3228-3238. (doi: 10.1002/eji.202048913) (PMID:34633664) (PMCID:PMC9214623)

Paterson, K., Zanivan, S. , Glasspool, R., Coffelt, S.B. and Zagnoni, M. (2021) Microfluidic technologies for immunotherapy studies on solid tumours. Lab on a Chip, 21(12), pp. 2306-2329. (doi: 10.1039/D0LC01305F) (PMID:34085677) (PMCID:PMC8204114)

McFarlane, A. J., Fercoq, F., Coffelt, S. B. and Carlin, L. M. (2021) Neutrophil dynamics in the tumor microenvironment. Journal of Clinical Investigation, 131(6), e143759. (doi: 10.1172/JCI143759) (PMID:33720040)

Edwards, S. C., Hoevenaar, W. H.M. and Coffelt, S. B. (2021) Emerging immunotherapies for metastasis. British Journal of Cancer, 124, pp. 37-48. (doi: 10.1038/s41416-020-01160-5) (PMID:33262520)

Coffelt, S. B. , Kabelitz, D., Silva-Santos, B., Kuball, J., Born, W. and Bank, I. (2020) Editorial: γδ T Cells in Cancer. Frontiers in Immunology, 11, 602411. (doi: 10.3389/fimmu.2020.602411) (PMID:33329597) (PMCID:PMC7714948)

Suzuki, T., Hayman, L., Kilbey, A., Edwards, J. and Coffelt, S. B. (2020) Gut γδ T cells as guardians, disruptors and instigators of cancer. Immunological Reviews, 298(1), pp. 198-217. (doi: 10.1111/imr.12916) (PMID:32840001)

Millar, R., Kilbey, A., Remak, S.-J., Severson, T. M., Dhayade, S., Sandilands, E., Foster, K., Bryant, D. M. , Blyth, K. and Coffelt, S. B. (2020) The MSP-RON axis stimulates cancer cell growth in models of triple negative breast cancer. Molecular Oncology, 14(8), pp. 1868-1880. (doi: 10.1002/1878-0261.12734) (PMID:32484599) (PMCID:PMC7400785)

Dhayade, S., Pietzke, M., Wiesheu, R., Tait-Mulder, J., Athineos, D., Sumpton, D., Coffelt, S. , Blyth, K. and Vazquez, A. (2020) Impact of formate supplementation on body weight and plasma amino acids. Nutrients, 12(8), 2181. (doi: 10.3390/nu12082181) (PMID:32708052) (PMCID:PMC7469024)

Muthalagu, N. et al. (2020) Repression of the type I interferon pathway underlies MYC & KRAS-dependent evasion of NK & B cells in pancreatic ductal adenocarcinoma. Cancer Discovery, 10(6), pp. 872-887. (doi: 10.1158/2159-8290.CD-19-0620) (PMID:32200350) (PMCID:PMC7611248)

Wellenstein, M. D. et al. (2019) Loss of p53 triggers Wnt-dependent systemic inflammation to drive breast cancer metastasis. Nature, 572, pp. 538-542. (doi: 10.1038/s41586-019-1450-6) (PMID:31367040) (PMCID:PMC6707815)

Mackey, J. B.G., Coffelt, S. B. and Carlin, L. M. (2019) Neutrophil maturity in cancer. Frontiers in Immunology, 10, 1912. (doi: 10.3389/fimmu.2019.01912) (PMID:31474989) (PMCID:PMC6702268)

Silva-Santos, B., Mensurado, S. and Coffelt, S. B. (2019) γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer. Nature Reviews Cancer, 19(7), pp. 392-404. (doi: 10.1038/s41568-019-0153-5) (PMID:31209264)

Salvagno, C. et al. (2019) Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response. Nature Cell Biology, 21(4), pp. 511-521. (doi: 10.1038/s41556-019-0298-1) (PMID:30886344) (PMCID:PMC6451630)

Kruspig, B. et al. (2018) The ERBB network facilitates KRAS-driven lung tumorigenesis. Science Translational Medicine, 10(446), eaao2565. (doi: 10.1126/scitranslmed.aao2565) (PMID:29925636) (PMCID:PMC6881183)

Rumney, R. M.H., Coffelt, S. B. , Neale, T. A., Dhayade, S., Tozer, G. M. and Miller, G. (2017) PyMT-Maclow: A novel, inducible, murine model for determining the role of CD68 positive cells in breast tumor development. PLoS ONE, 12(12), e0188591. (doi: 10.1371/journal.pone.0188591) (PMID:29220404) (PMCID:PMC5722323)

Walton, J. B. et al. (2017) CRISPR/Cas9-derived models of ovarian high grade serous carcinoma targeting Brca1, Pten and Nf1, and correlation with platinum sensitivity. Scientific Reports, 7, 16827. (doi: 10.1038/s41598-017-17119-1) (PMID:29203787) (PMCID:PMC5715106)

Carron, E. C., Homra, S., Rosenberg, J., Coffelt, S. B. , Kittrell, F., Zhang, Y., Creighton, C. J., Fuqua, S. A., Medina, D. and Machado, H. L. (2017) Macrophages promote the progression of premalignant mammary lesions to invasive cancer. Oncotarget, 8(31), pp. 50731-50746. (doi: 10.18632/oncotarget.14913) (PMID:28159924)

van Baal, J.O.A.M., Van de Vijver, K.K., Coffelt, S.B. , van der Noort, V., van Driel, W.J., Kenter, G.G., Buist, M.R. and Lok, C.A.R. (2017) Incidence of lymph node metastases in clinical early-stage mucinous and seromucinous ovarian carcinoma: a retrospective cohort study. BJOG: An International Journal of Obstetrics and Gynaecology, 124(3), pp. 486-494. (doi: 10.1111/1471-0528.14425) (PMID:27860146)

Kersten, K. et al. (2017) Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages. OncoImmunology, 6(8), e1334744. (doi: 10.1080/2162402X.2017.1334744) (PMID:28919995) (PMCID:PMC5593698)

Coffelt, S. B. , Wellenstein, M. D. and de Visser, K. E. (2016) Neutrophils in cancer: neutral no more. Nature Reviews Cancer, 16(7), pp. 431-446. (doi: 10.1038/nrc.2016.52) (PMID:27282249)

Coffelt, S. B. and de Visser, K. E. (2016) Revving up dendritic cells while braking PD-L1 to jump-start the cancer-immunity cycle motor. Immunity, 44(4), pp. 722-724. (doi: 10.1016/j.immuni.2016.03.014) (PMID:27096314)

Coffelt, S. B. and de Visser, K. E. (2016) Systemic inflammation: Cancer's long-distance reach to maximize metastasis. OncoImmunology, 5(2), e1075694. (doi: 10.1080/2162402X.2015.1075694) (PMID:27057449) (PMCID:PMC4801429)

Rahat, M. A., Coffelt, S. , Granot, Z., Muthana, M. and Amedei, A. (2016) Macrophages and neutrophils: regulation of the inflammatory microenvironment in autoimmunity and cancer. Mediators of Inflammation, 2016, 5894347. (doi: 10.1155/2016/5894347) (PMID:27725789) (PMCID:PMC5048028)

Doornebal, C. W., Vrijland, K., Hau, C.-S., Coffelt, S. B. , Ciampricotti, M., Jonkers, J., de Visser, K. E. and Hollmann, M. W. (2015) Morphine does not facilitate breast cancer progression in two preclinical mouse models for human invasive lobular and HER2+ breast cancer. Pain, 156(8), pp. 1424-1432. (doi: 10.1097/j.pain.0000000000000136) (PMID:25734987)

Coffelt, S. B. et al. (2015) IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis. Nature, 522(7556), pp. 345-348. (doi: 10.1038/nature14282) (PMID:25822788) (PMCID:PMC4475637)

Coffelt, S. B. and de Visser, K. E. (2015) Immune-mediated mechanisms influencing the efficacy of anticancer therapies. Trends in Immunology, 36(4), pp. 198-216. (doi: 10.1016/j.it.2015.02.006) (PMID:25857662)

Al-ofi, E., Coffelt, S. B. and Anumba, D. O. (2014) Fibrinogen, an endogenous ligand of Toll-like receptor 4, activates monocytes in pre-eclamptic patients. Journal of Reproductive Immunology, 103, pp. 23-28. (doi: 10.1016/j.jri.2014.02.004) (PMID:24661950)

Coffelt, S. B. and de Visser, K. E. (2014) Cancer: Inflammation lights the way to metastasis. Nature, 507(7490), pp. 48-49. (doi: 10.1038/nature13062) (PMID:24572360)

Gheryani, N., Coffelt, S. B. , Gartland, A., Rumney, R. M.H., Kiss-Toth, E., Lewis, C. E., Tozer, G. M., Greaves, D. R., Dear, T. N. and Miller, G. (2013) Generation of a novel mouse model for the inducible depletion of macrophages in vivo. genesis, 51(1), pp. 41-49. (doi: 10.1002/dvg.22343) (PMID:22927121)

Al-Ofi, E., Anumba, D.O.C. and Coffelt, S. (2012) OS006. Functional expression of endogenous ligands of Toll like receptor4 on monocytes and placentae from women during normal pregnancy andpre-eclampsia. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2(3), p. 178. (doi: 10.1016/j.preghy.2012.04.008) (PMID:26105221)

Wu, W.K.K., Coffelt, S.B. , Cho, C.H., Wang, X.J., Lee, C.W., Chan, F.K.L., Yu, J. and Sung, J.J.Y. (2012) The autophagic paradox in cancer therapy. Oncogene, 31(8), pp. 939-953. (doi: 10.1038/onc.2011.295) (PMID:21765470)

Coffelt, S. B. et al. (2011) Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion. Journal of Immunology, 186(7), pp. 4183-4190. (doi: 10.4049/​jimmunol.1002802) (PMID:21368233)

Welford, A. F. et al. (2011) TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice. Journal of Clinical Investigation, 121(5), pp. 1969-1973. (doi: 10.1172/JCI44562) (PMID:21490397) (PMCID:PMC3083764)

Muthana, M. et al. (2011) Use of macrophages to target therapeutic adenovirus to human prostate tumors. Cancer Research, 71(5), pp. 1805-1815. (doi: 10.1158/0008-5472.CAN-10-2349) (PMID:21233334)

Coffelt, S. B. et al. (2010) Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions. Cancer Research, 70(13), pp. 5270-5280. (doi: 10.1158/0008-5472.CAN-10-0012) (PMID:20530679)

Wu, W. K.K., Wang, G., Coffelt, S. B. , Betancourt, A. M., Lee, C. W., Fan, D., Wu, K., Yu, J., Sung, J. J.Y. and Cho, C. H. (2010) Emerging roles of the host defense peptide LL-37 in human cancer and its potential therapeutic applications. International Journal of Cancer, 127(8), pp. 1741-1747. (doi: 10.1002/ijc.25489) (PMID:20521250) (PMCID:PMC2930073)

Coffelt, S. B. , Lewis, C. E., Naldini, L., Brown, J. M., Ferrara, N. and De Palma, M. (2010) Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors. American Journal of Pathology, 176(4), pp. 1564-1576. (doi: 10.2353/ajpath.2010.090786) (PMID:20167863) (PMCID:PMC2843445)

Fang, H.-Y. et al. (2009) Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Blood, 114(4), pp. 844-859. (doi: 10.1182/blood-2008-12-195941) (PMID:19454749) (PMCID:PMC2882173)

Coffelt, S. B. , Tomchuck, S. L., Zwezdaryk, K. J., Danka, E. S. and Scandurro, A. B. (2009) Leucine leucine-37 uses formyl peptide receptor-like 1 to activate signal transduction pathways, stimulate oncogenic gene expression, and enhance the invasiveness of ovarian cancer cells. Molecular Cancer Research, 7(6), pp. 907-915. (doi: 10.1158/1541-7786.MCR-08-0326) (PMID:19491199) (PMCID:PMC2755540)

Coffelt, S. B. et al. (2009) The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells. Proceedings of the National Academy of Sciences of the United States of America, 106(10), pp. 3806-3811. (doi: 10.1073/pnas.0900244106) (PMID:19234121) (PMCID:PMC2656161)

Coffelt, S. B. and Scandurro, A. B. (2008) Tumors sound the alarmin(s). Cancer Research, 68(16), pp. 6482-6485. (doi: 10.1158/0008-5472.CAN-08-0044) (PMID:18701469) (PMCID:PMC2755533)

Murdoch, C., Muthana, M., Coffelt, S. B. and Lewis, C. E. (2008) The role of myeloid cells in the promotion of tumour angiogenesis. Nature Reviews Cancer, 8(8), pp. 618-631. (doi: 10.1038/nrc2444) (PMID:18633355)

Xiang, S., Coffelt, S. B. , Mao, L., Yuan, L., Cheng, Q. and Hill, S. M. (2008) Period-2: a tumor suppressor gene in breast cancer. Journal of Circadian Rhythms, 6(1), p. 4. (doi: 10.1186/1740-3391-6-4) (PMID:18334030) (PMCID:PMC2365929)

Tomchuck, S. L., Zwezdaryk, K. J., Coffelt, S. B. , Waterman, R. S., Danka, E. S. and Scandurro, A. B. (2008) Toll-like receptors on human mesenchymal stem cells drive their migration and immunomodulating responses. Stem Cells, 26(1), pp. 99-107. (doi: 10.1634/stemcells.2007-0563) (PMID:17916800) (PMCID:PMC2757778)

Coffelt, S. B. , Waterman, R. S., Florez, L., Bentrup, K. H. z., Zwezdaryk, K. J., Tomchuck, S. L., LaMarca, H. L., Danka, E. S., Morris, C. A. and Scandurro, A. B. (2007) Ovarian cancers overexpress the antimicrobial protein hCAP-18 and its derivative LL-37 increases ovarian cancer cell proliferation and invasion. International Journal of Cancer, 122(5), pp. 1030-1039. (doi: 10.1002/ijc.23186) (PMID:17960624)

Zwezdaryk, K. J., Coffelt, S. B. , Figueroa, Y. G., Liu, J., Phinney, D. G., LaMarca, H. L., Florez, L., Morris, C. B., Hoyle, G. W. and Scandurro, A. B. (2007) Erythropoietin, a hypoxia-regulated factor, elicits a pro-angiogenic program in human mesenchymal stem cells. Experimental Hematology, 35(4), pp. 640-652. (doi: 10.1016/j.exphem.2007.01.044) (PMID:17379074)

Abboud, E. R., Coffelt, S. B. , Figueroa, Y. G., Zwezdaryk, K. J., Nelson, A. B., Sullivan, D. E., Morris, C. B., Tang, Y., Beckman, B. S. and Scandurro, A. B. (2007) Integrin-linked kinase: a hypoxia-induced anti-apoptotic factor exploited by cancer cells. International Journal of Oncology, 30(1), pp. 113-122. (doi: 10.3892/ijo.30.1.113) (PMID:17143519)