Gynaecological (uterine/ovarian)
Gynaecological cancer is one of the six research themes in the Cancer Research UK Scotland Centre & is also integral to Glasgow Experimental Cancer Medicines Centre.
• Early-phase ovarian cancer clinical trials.
• Identification of strategies to evade PARP inhibitor (PARPi) resistance in high grade serous ovarian cancer.
• Research into the genomic landscape of ovarian cancer tumour genesis in high risk BRCA 1 / 2 mutation carriers.
• Identification of novel therapies for low grade serous ovarian cancer.
• Spatial analysis of cancer associated with fibroblast subtypes in high grade serous ovarian carcinoma. The date generated will enable researchers to understand which cell types have the most effect on how a tumour grows and how it responds to chemotherapy.