Epidemiology of Foot-and-Mouth Disease

Epidemiology of Foot-and-Mouth Disease

[work carried out in collaboration with IAH-Pirbright]

Project Questions and Objectives

This project encompasses a broad range of questions, amongst which are:

  • How quickly does FMDV evolve in the field?
  • How quickly does FMDV evolve during a single individual infection?
  • Does the concept of quasi-species help us to understand viral evolution?
  • At what resolution can we trace transmission pathways using RNA sequence data?
  • How does observed sequence variation translate into antigenic diversity?
  • Can we test vaccine potency without using animal challenge experiments
  • What lessons can we learn about the control of FMDV from the UK 2001 outbreak?

Project Description

This work is conducted in close collaboration with many colleagues and is of a very varied nature.

References and Manuscripts