Professor Manuel Salmeron-Sanchez
Chair of Biomedical Engineering
‘We are leading research in the use of stem cells in regenerative medicine. This is a collaboration of scale, using new engineering technologies to tackle challenges and deliver outcomes across a range of medical problems.’
Professor Manuel Salmeron-Sanchez is Head of the Division of Biomedical Engineering and Chair of Biomedical Engineering in the School of Engineering. Manuel works on material-based strategies to engineer tissue repair and regeneration, and to understand pathological conditions such as cancer. His multidisciplinary group (Microenvironments for Medicine - MiMe) designs microenvironments to simulate the complex spatio-temporal cues of the extracellular matrix.
Manuel and his research group have established a robust partnership with Professor Matt Dalby at the Centre for Cell Engineering. Together with key local and international collaborators, they address a broad range of topics within this field, including the design of biomaterials/biointerfaces, protein adsorption, growth factors and their interactions with the extracellular matrix, cell adhesion, protein remodelling and stem cell differentiation at the material interface. MiMe and CCE target translational research to address unmet clinical needs such as bone regeneration in critical size defects as well as radical new approaches to control stem cells using synthetic biology.
Manuel, Matt and their research team recently received £6.8 million in grant funding from landmine victim charity Find A Better Way and EPSRC to progress Regenerative Medicine research. These grants will fund development of a technique to improve bone-growth-promoting treatments while reducing side effects as well as other technologies to target cardiomyocytes and hematopoietic stem cells in regenerative medicine.
Professor Salmeron-Sanchez's research focuses on the development of material surfaces to trigger the self-assembly of proteins. This work spans fundamental mechanisms at the cell/material interface as well as translational research.