We use stable isotopes to investigate complex biological and environmental processes from cells to humans and beyond to whole landscapes. We measure biologically and chemically driven changes in the natural abundance of isotopes (2H, 13C, 15N, 18O) at the molecular (compound-specific) level. We also measure labelled (enriched) substrates, exploiting isotope tracers in our research to probe multiple metabolic processes to provide mechanistic insight into complex biological systems including human health and disease.

Stable Isotope Biochemistry

Get in touch: Prof Douglas Morrison

 
Environment & Health  Innovation & Technology 
 

Projects

  • 13 Oct

    GITools

    Novel tools for evaluating intestinal dysfunction in children and adults with malnutrition disorders
  • 13 Oct

    iPREVENT

    Increase colonic propionate as a method of preventing weight gain in adults aged 20-40 years.
  • 13 Oct

    Impact of protein quality and fibre in ageing

    Exploring the impact of protein quality and fibre on gut barrier function, inflammation and body composition in ageing.
Full lab project listings

Techniques & Technologies

GC-C-IRMS & GC-P-IRMS

compound specific 13C, 2H & 15N in carbohydrates, lipids, amino acids and other small molecules

GC-MS & LC-MS/MS

13C, 2H & 15N enrichment in biological and environmental samples for human isotope labelling studies of gut function, microbiome activity, obesity and malnutrition

FTIR

D/H ratios in waters, saliva, urine, plasma for studies of body composition and energy expenditure in humans

Biological safety level 2 lab

to receive and process biological and clinical samples

People