Publications

Journal Papers | Book Chapters | Conference Proceedings | Case Studies | Workshops & Presentations

Peer Reviewed Journal Papers

J. Faerber, G. Cummins, S. K. Pavuluri, P. Record, A. R. A. Rodriguez, H. S. Lay, R. McPhillips, B. F. Cox, C. Connor, R. Gregson, R. E. Clutton, S. R. Khan, S. Cochran, and M. P. Y. Desmulliez, “In Vivo Characterization of a Wireless Telemetry Module for a Capsule Endoscopy System Utilizing a Conformal Antenna,” IEEE Trans. Biomed. Circuits Syst., vol. TBA, no. TBA, pp. 1–11, 2017.

G. Cummins, D. E. Yung, B. F. Cox, A. Koulaouzidis, M. P. Y. Desmulliez, and S. Cochran, “Luminally expressed gastrointestinal biomarkers,” Expert Rev. Gastroenterol. Hepatol., vol. 11, no. 12, pp. 1119–1134, Dec. 2017

Lay, HS, Cox, BF, Seetohul, V, Démoré, CEM, Cochran, S, “Design and Simulation of a Ring-Shaped Linear Array for Microultrasound Capsule Endoscopy,” Transactions of Ultrasonics, Ferroelectrics and Frequency Control, Volume: PP, Issue:99, 2018. DOI:10.1109/TUFFC.2018.2794220 (In press)

F.W.Stewart et al, “Acoustic Sensing and Ultrasonic Drug Delivery in Multimodal Theranostic Capsule Endoscopy”, to submit to Acoustic Sensing and Ultrasonic Drug Delivery, Submitted to MDPI Sensors, 2017.

F.R.Stewart et al, “A Prototype Therapeutic Capsule Endoscope for Ultrasound-mediated Targeted Drug Delivery” In J. Med. Robotics Res., 2017. Accepted, in press.

H. McLeod, B. F. Cox, J. Robertson, R. Duncan, S. Matthew, R. Bhat, A. Barclay, J. Anwar, T. Wilkinson, A. Melzer, and J. G. Houston, Human Thiel-Embalmed Cadaveric Aortic Model with Perfusion for Endovascular Intervention Training and Medical Device Evaluation, Cardiovasc. Intervent. Radiol. Apr. 2017.

Lay HS, Cox BF, Sunoqrot M, Démoré CEM, Näthke I, Gomez T, Cochran, S. Microultrasound characterisation of ex vivo porcine tissue for ultrasound capsule endoscopy. J Phys Conf Ser. 2017 Jan;797:12003.

B.F. Cox, F. Stewart, H. Lay, G. Cummins, I.P. Newton, M.P.Y. Desmulliez, R.J.C. Steele, I. Näthke and S. Cochran, Ultrasound capsule endoscopy: sounding out the future, Ann Transl. Med. 2017 May;5(9):201. http://dx.doi.org/10.21037/atm.2017.04.21.

V. Mitrakos, L. Macintyre, F.C. Denison, P.J.W. Hands and M.P.Y. Desmulliez, Design, manufacture and testing of capacitive pressure sensors for low-pressure measurement ranges. Micromachines, 2017, 8(2)

S. Mahboob, R. McPhillips, Z. Qiu, Y. Jiang, C. Meggs, G. Schiavone, T. Button, M. Desmulliez, C. Demore, S. Cochran, S. Ejamel, Intraoperative ultrasound (IoUS) guided resection of Gliomas: a Meta-analysis, Word Neurosurgery, DOI: http://dx.doi.org/10.1016/j.wneu.2016.05.007. (IF 2.88).

Boccito, M., Doshi, S., Newton, I.P., Näthke, I., Neve, R., Dong, F., Mao, Y., Zhai, J., Zhang, L., Kalb, R., “Opposing actions of the Synapse Associated Protein of 97kDa Molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/b-catenin signaling”, (2016), Neuroscience, March 26 pii: S0306-4522(16)30027-6. doi:10.1016/j.neuroscience.2016.03.048

Dunn S.J., Osborne, J., AppletonP.L., NäthkeI. “Combined changes in Wnt signalling response and contact inhibition induce altered proliferation in radiation treated intestinal crypts”, (2016), Mol. Biol. Cell27:1863-74.

Langlands, A.J., Almet, A.A., Appleton, P.L. Newton, I.P., Osborne, J.M., Näthke, I., “Paneth cell – rich regions separated by a cluster of Lgr5+ cells initiate crypt fission in the intestinal stem cell niche”, (2016), PLoS Biology,14(6):e1002491

Fatehullah, A., Sharma, S., Newton,I.P., Langlands, A,J., Lay, H., Nelson, S.A., McMahon, R.K., McIlvenny, N., Appleton, P.L., Cochran, S,, Näthke, I.S., “Increased variability in APCMin/+ instestinal tissue can be measured with microultrasound”, (2016) Sci Rep6:29570 (9 citations)

G. Schiavone, T. Jones, D. Price, R. McPhillips, Y. Jiang, Z. Qiu, C. Meggs, S.O. Mahboob, S. Eljamel, T.W. Button, C.E.M. Demore, S. Cochran and M.P.Y. Desmulliez, A highly compact packaging concept for ultrasound transducer arrays embedded in neurosurgical needles, J. of Microsyst. Technol., DOI 10.1007/s00542-015-2775-1

Al-Rawhani M, Beeley J, Cumming DRS “Wireless Fluorescence Capsule for Endoscopy Using Single Photon-Based Detection” Nature Scientific Reports 5, Article number: 18591 (2015). doi:10.1038/srep18591

Qiu Y, Wang H, Gebhardt S, Bolhovitins A, Démoré CEM, Schönecker A, & Cochran S. (2015). Screen-printed ultrasonic 2-D matrix array transducers for microparticle manipulation. Ultrasonics, 62, 136–146. http://doi.org/10.1016/j.ultras.2015.05.010.

Qiu Y, Gigliotti J, Wallace M, Griggio F, Demore CEM, Cochran S, & Trolier-McKinstry S. (2015). Piezoelectric micromachined ultrasound transducer (PMUT) arrays for integrated sensing, actuation and imaging. Sensors, 15(4), 8020–8041. http://doi.org/10.3390/s150408020

Y. Jiang, Z. Qiu, R. McPhilips, C. Meggs, S. Mahboob, H. Wang, R. Duncan, D. Rodriguez-Martin, Y. Zhang, G. Schiavone, M. Desmulliez, S. Eljamel, S. Cochran, T.W. Button, C. Demore, Dual orientation 16 MHz single element ultrasound needle transducers for image-guided neurosurgical intervention, IEEE Trans. Ultras., Ferro. and Freq. Control., pp. 233-244, TUFFC-07374-2015.

Al-Rawhani MA, Beeley J, Chitnis DC, Steve C, and Cumming, DRS “Wireless Capsule For Autofluorescence Detection In Biological Systems”, Sensors and Actuators B: Chemical, 189, 203 – 7, 2013.

Al-Rawhani M, Chitnis D, Beeley J, Collins S, and Cumming DRS “Design And Implementation of a Wireless Capsule Suitable for Autofluorescence Intensity Detection In Biological Tissues” IEEE Trans. Biomed. Eng. 60 (1) 55 – 62, 2013.

Bernassau AL, Al-Rawhani M, Beeley J and Cumming, DRS “Integrated ultrasonic particle positioning and low excitation light fluorescence imaging”, Applied Physics Letters, 103, 244103 (2013). 

Book Chapters

Lay, HS and Cochran, S, “Circuits and Systems for Biosensing with Microultrasound,” in CMOS Circuits for Biological Sensing and Processing, Springer, Cham, 2018, pp. 187–209. DOI:10.1007/978-3-319-67723-1_8

F.R.Stewart et al, "Theranostics in the Gut." In Theranostics and Image Guided Drug Delivery, pp. 182-210. 2018.

Anbarasan T, Démoré CEM, Lay H, Sunoqrot MRS, Poltarjonoks R, Cochran S, Cox BF Development of small bowel tissue phantom for microultrasound (μUS) investigation. ln: Rasooly A., Pickril B. (Eds.), Biosensor Technologies. Springer, 2016.

Conference Proceedings

G. Cummins, J. Gao, R. McPhillips, D. Watson, S. Cochran, and M. P. Y. Desmulliez, “Optimization and Characterisation of Bonding of Piezoelectric Transducers using Anisotropic Conductive Adhesive,” in IEEE International Ultrasonics Symposium, IUS, 2017, p. TBD.

F.R.Stewart et al, “Development of a Therapeutic Capsule Endoscope for Treatment in the Gastrointestinal Tract: Bench Testing to Translational Trial” IEEE International Ultrasonics Symposium, 2017

Lay, HS, Cummins, G, Cox, BF, Qiu, Y, Connor, C, Seetohul, V, Turcanu, M, McPhillips, R, Desmulliez, MPY, Clutton, E, Cochran, S, “Translational trial outcomes for capsule endoscopy test devices”, in 2017 IEEE International Ultrasonics Symposium (IUS), 2017, pp. 1–4 DOI: 10.1109/ULTSYM.2017.8091826.

S.Cochran et al., “Nanotechnology in Multimodal Theranostic Capsule Endoscopy”. IEEE Nano Conference 2017.

J. Faerber, G. Cummings, M.P.Y. Desmulliez, Design of conformal wideband antennas for capsule endoscopy within a body tissue environment, Proc. of the 46th European Microwave Conference (EUMW), pp. 1224-1226.

H.S. Lay, Y. Qiu, R. McPhillips, M. Al-Rawhani, J. Beeley, B.F. Cox, V. Seetohul, G. Cummins, C. Demore, M. Wallace, S. Trolier-McKinstry, M.P.Y. Desmulliez, D. Cumming, S. Cochran, Progress towards a multi-modal capsule endoscopy device featuring microultrasound imaging, 2016 IEEE International Ultrasonics Symposium.

M.D. Farinas, G. Cummins, V. Seetohul, M.P.Y. Desmulliez, S. Cochran, T.E.G. Alvarez-Arenas, Assessment of the ultrasonic principles of additive manufactured materials for passive components of piezoelectric transducers, ID: 1158, 2016 IEEE International Ultrasonics Symposium.

G. Cummins, V. Seetohul, Y.  Qiu, K. Wlodarczyk, W.A. Lewinger, H.Lay, B. Cox, D. Hand, C. Demore, M.P.Y. Desmulliez, S. Cochran, Sonopill Pathfinder: Rapid prototyping for ultrasound capsule endoscopy, P34, Proc. of the 9th Hamlyn Symposium on Medical Robotics.

Stewart F., Wang G., Newton I.P., Cox B.F., Thanou M., Huang Z., Näthke I., Cochran S., An in vitro Sonication System for Applications in Ultrasound-mediated Targeted Drug Delivery. Proceedings 2016 International Ultrasonics Symposium.

Cox B.F., Stewart F., Huang Z., Näthke I., Cochran S., Ultrasound Mediated Tattooing of Gastrointestinal Tissue with Fluorescent Material. Proceedings 2016 International Ultrasonics Symposium.

Anbarasan T, Démoré CEM, Lay H, Sunoqrot MRS, Poltarjonoks R, Cox BF, Cochran S. “Development of Small Bowel Tissue Phantom for Microultrasound (μUS) Investigation” Proc 2015 RSM-UKMSA Conf.

Cummins G, Desmulliez MPY, Characterisation of adhesive bonds for ingestible biomedical applications. Proceedings 2015 Electronic Packaging and Technology Conference.

Cox BF, Seetohul V, Lay H, Cochran S., “Microultrasound and Small Bowel Inflammation: Tissue Phantom Studies” Proc. 2015 Int. Ultrason. Symp, Taiwan.

Desmulliez, MPY, “Novel packaging for integration of ultrasonic transducers in surgical needles”, Proc. of the 4th International Conference in Advanced manufacturing for Multifunctional Miniaturised Devices.

Faerber J and Desmulliez MPY “Conformal Meander Shaped Antenna for Biotelemetry in Endoscopic Capsules” Proc. 2015 Loughborough Antennas and Propagation Conf.

Lay HS, Seetohul V, Cox BF, Demore CEM, Cochran S. “Design and Simulation of a High-Frequency Ring-Shaped Linear array for Capsule Ultrasound Endoscopy”, Proc. 2014 Int. Ultrason. Symp., pp. 683 - 6.

Lay HS, Poltarjonoks R, Ndum F, Lines D, Lockwood GR, Cochran S. “Development of a Hybrid Custom / Commercial Multi-Channel, High-Frequency Transmit Pulser and Beamformer System”, Proc. 2015 Int. Ultrason. Symp (in press).

Schiavone G, Jones T, Price D McPhillips R, Qiu Z, Demore CME, Jiang Y, Meggs C, Mahboob S, Button TW, Cochran S, Desmulliez MPY, “A compact packaging technique for the integration of ultrasound probes in surgical needles”, Proceedings of the IEEE Conf. in Design, Test, Integration and Packaging of MEMS/MOEMS 2015.

Stewart F, Verbeni A, Qiu Y, Cox BF, Vorstius J, Cochran S. “Capsule-based Ultrasound-mediated Targeted Gastrointestinal Drug Delivery” Proc. 2015 Int. Ultrason. Symp., 2015, Taiwan (short-listed for student prize).

Verbeni A, Stewart F, Qiu Y, Cox BF, Vorstius J, Cochran S. “SonoCAIT: Sonication Capsule for Autonomous Imaging and Therapy, a Proof of Concept Device” 37th Ann. Int. Conf. IEEE Eng. Med. Biol. Soc, Turin, Italy, Sep. 2015.

Wang J, Xiao X, Duncan R, McLeod H, Cox BF, Melzer A. Ex-vivo Perfused Swine Kidney Simulating in FUS Therapy. Proc. 2015 Int. Ultrason. Symp., Taiwan.

Industry Case Studies

Ndum F, Poltarjonoks R, Lines D, Cochran S, and Lay H, National Instruments engineering case study “Prototyping Micro-Ultrasound Instruments for Medical Imaging”, sine.ni.com/cs/app/doc/p/id/cs-16791, 2015.

Workshop and Conference Presentations

F.R.Stewart, I.P.Newton, B.F.Cox, Z.Huang, I.Nathke, S.Cochran, “Development of a Therapeutic Capsule Endoscope for Treatment in the Gastrointestinal Tract: Bench Testing to Translational Trial” IEEE International Ultrasonics Symposium, 2017. Oral Presentation

F.R.Stewart, Y.Liu, P.Roncin,  I.P.Newton, Z.Huang, I.Nathke, S.Cochran, “A Fully Automated Insonation System for In Vitro Investigations of Ultrasound-mediated Targeted Drug Delivery” IEEE International Ultrasonics Symposium, 2017. Oral Presentation

V.Bentivegna, F.R.Stewart, S.Cochran, I.Nathke, “Acoustic Radiation Pressure as a Versatile Tool for Cell Biology and Mechanobiology Studies” IEEE International Ultrasonics Symposium, 2017. Poster Presentation

Al-Rawhani, M. A. et al., Wide-range optical CMOS-based diagnostics, IEEE International Symposium on Circuits and Systems (ISCAS). 2017. (Accepted for lecture).

 Y. Qiu, C. Cheng, H. Lay, A. Welsh, M. Wallace, S. Trolier-McKinstry, S. Cochran, “Thin Film PZT-based PMUT arrays for microultrasound capsule endoscopy”, IEEE International Ultrasonics Symposium Proceedings, Washington DC, USA, 2017 (Abstract accepted)

 Y. Qiu, R. McPhillips, Y. Jiang, Z. Qiu, H. Lay, B. F. Cox, T. Button, C. Demore, S. Cochran, “1-3 piezoelectric composite-based ultrasonic devices for ultrasound imaging, therapy and microparticle manipulation”, International Symposium on Piezocomposite Applications, Dresden, Germany, 2017 (Abstract accepted)

Yongqiang:  Y. Qiu, H. Lay, V. Seetohul, C. Connor, M.Turcanu, S. Cochran, B. Cox, G. Cummins, M.P.Y. Desmulliez, R. Gregson and E. Clutton, “Experience and lessons from translational trials of Sonopill’s first prototypes”, Scottish Ultrasound Inaugural Annual Scientific Meeting, Edinburgh, UK, 8 March 2017

CMOS ASIC Design for High Frequency Ultrasound Capsule Endoscope. James Beeley, Mohammed Al-Rawhani, Yongqiang Qiu, Rachael McPhillips, Holly Lay, Sandy Cochran, David Cumming

Cell and Developmental Biology Internal Seminars, School of Life Sciences, University of Dundee – December 2016. Dundee, Scotland. Oral presentation. “Capsule-based Ultrasound-mediated Targeted Drug Delivery”

Surgery & Oncology Seminar Series, School of Medicine, University of Dundee – June 2017. Dundee, Scotland. Oral presentation. “Capsule-based Ultrasound-mediated Targeted Drug Delivery”

Cox BF “Capsule sonography – a brief insight of the Sonopill” Invited speaker, at An Update on the use of Capsule Endoscopy in IBD. Hosted by Dr A.Koulaouzidis – Endoscopy Unit, Royal Infirmary of Edinburgh, Sep. 2015.

Cox BF “The Sonopill Programme” 4th Oncological Eng. Conf., Leeds, 2015.

Lay HS, Poltarjonoks R, Démoré CEM, Cochran S. “Electrical and Acoustic Materials Characterisation of Micro‚ÄźUltrasound Transducers”, UK Ferroelectrics 2015.

Stewart F, Verbeni A, Qiu Y, Cox BF, Vorstius J, Cochran S. “Capsule-based Ultrasound-mediated Targeted Drug Delivery” UK Therapeutic Ultrasound Interest Group meeting, May 2015.

Stewart F, Verbeni A, Cochran S. “SonoCAIT: Sonication Capsule for Autonomous Imaging and Therapy” 4th Oncological Eng. Conf., Leeds, Mar. 2015.

Stewart F, Verbeni A, Qiu Y, Cox BF, Vorstius J, Cochran S. “Capsule-based Ultrasound-mediated Targeted Gastrointestinal Drug Delivery” 3rd European Symposium on Focused Ultrasound Therapy, London, Oct. 2015.

Seetohul V, Cochran S, Cox BF “Robotic requirements for diagnosis and therapy with ultrasound capsule endoscopy” Invited Speaker, IEEE/RSJ 2015 Int. Conf. on Intelligent Robots and Sys., Hamburg, Germany, 2015.

Cochran S, Cox BF, Lay H, “Ultrasound capsule endoscopy for diagnosis and therapy: A new frontier in autonomous, robotic systems.” Invited Speaker, CDT Gateway Events, Heriot-Watt University, November 2014.

Seetohul V, Faerber J, Demore C, Cochran S. “Simple microultrasound capsule endoscopy” Ultrason. Biomed. Microscanning 2014, 9th International Conference, Scotland, 2014.