Professor Matthew Dalby
- Professor of Cell Engineering, Director of innovation, Engagement and Enterprise (Molecular Biosciences)
telephone:
01413303550
email:
Matthew.Dalby@glasgow.ac.uk
B3-10, Institute of MC&SB, Joseph Black Building, Glasgow G12 8QQ
https://orcid.org/0000-0002-0528-3359Biography
Obtaining a PhD in Biomedical Materials from Queen Mary, University of London on osteoblast response to the topography and composition of hydroxyapatite containing composite materials, I moved to Glasgow to join Cell Engineering as a PDRA on EU grant Nanomed. Here I researched how cells interacted with nanoscale features producing early literature on cellular ability to respond to nanotopography. During this time I became focussed on dissecting how cells processed nanoscale information through mechanotransductive processes. Together, these interests in bone, nanotopography and mechanotransduction led me to apply for a BBSRC David Phillips Fellowship in 2003. During this fellowship I focussed on how mesenchymal stem cells were directed to differentiate and to self-renew by nanotopography and this led to a lectureship in Cell Engineering in 2008. Now, as Professor of Cell Engineering, I am still fascinated by the nanoscale and mechanotransductive processes, but my interests have broadened to include metabolomics-based research and a growing interest in how growth factors can be controlled at the nanoscale to direct stem cell fate.
Research interests
- Adult stem cell interactions with nanotopography, dynamic (cell responsive) surfaces, 3D hydrogels and growth factors organising interfaces.
- Metabolomics for stem cells.
- Stem cell mechanotransduction.
Research interests - further information
Centre for the Cellular Microenvironment (CeMi)
Research groups
- Regenerative Medicine & Cellular Microenvironment
Publications
2024
Cuahtecontzi Delint, R., Jaffery, H., Ishak, M. I., Nobbs, A. H., Su, B. and Dalby, M. J. (2024) Mechanotransducive surfaces for enhanced cell osteogenesis, a review. Biomaterials Advances, (doi: 10.1016/j.bioadv.2024.213861) (In Press)
Dhawan, U. , Williams, J. A., Windmill, J. F.C., Childs, P., Gonzalez-Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2024) Engineered surfaces that promote capture of latent proteins to facilitate integrin-mediated mechanical activation of growth factors. Advanced Materials, (doi: 10.1002/adma.202310789) (PMID:38253339) (Early Online Publication)
2023
Busch, C., Mulholland, T., Zagnoni, M., Dalby, M. , Berry, C. and Wheadon, H. (2023) Overcoming BCR::ABL1 dependent and independent survival mechanisms in chronic myeloid leukaemia using a multi-kinase targeting approach. Cell Communication and Signaling, 21, 342. (doi: 10.1186/s12964-023-01363-2) (PMID:38031192) (PMCID:PMC10685629)
Sanchez-Rubio, A., Jayawarna, V., Maxwell, E., Dalby, M. J. and Salmeron-Sanchez, M. (2023) Keeping it organized: multicompartment constructs to mimic tissue heterogeneity. Advanced Healthcare Materials, 12(17), 2202110. (doi: 10.1002/adhm.202202110) (PMID:36938891)
Dhawan, U. , Wang, W.-L., Lin, Y.-C., Yang, R.-B., Dalby, M. J. , Salmeron-Sanchez, M. and Yu, H.-h. (2023) Mechanostimulation-induced integrin αvβ6 and latency associated peptide coupling activates TGF-β and regulates cancer metastasis and stemness. Nano Today, 50, 101882. (doi: 10.1016/j.nantod.2023.101882)
Sarrigiannidis, S. O., Dobre, O. , Navarro, A. R., Dalby, M. J. , Gonzalez-Garcia, C. and Salmeron-Sanchez, M. (2023) Engineered dual affinity protein fragments to bind collagen and capture growth factors. Materials Today Bio, 20, 100641. (doi: 10.1016/j.mtbio.2023.100641) (PMID:37179535) (PMCID:PMC10173277)
Sonam, S., Malmstrom, J., Kamei, K.-i. and Dalby, M. J. (2023) Editorial: Materials for mechanotransduction and beyond. Frontiers in Cell and Developmental Biology, 11, 1222957. (doi: 10.3389/fcell.2023.1222957) (PMID:37305678) (PMCID:PMC10250702)
Donnelly, H., Kurjan, A., Yong, L. Y., Xiao, Y., Lemgruber, L. , West, C., Salmeron-Sanchez, M. and Dalby, M. J. (2023) Fibronectin matrix assembly and TGFβ1 presentation for chondrogenesis of patient derived pericytes for microtia repair. Biomaterials Advances, 148, 213370. (doi: 10.1016/j.bioadv.2023.213370) (PMID:36931082)
Ishak, M. I., Eales, M., Damiati, L., Liu, X., Jenkins, J., Dalby, M. J. , Nobbs, A. H., Ryadnov, M. G. and Su, B. (2023) Enhanced and stem-cell-compatible effects of nature-inspired antimicrobial nanotopography and antimicrobial peptides to combat implant-associated infection. ACS Applied Nano Materials, 6(4), pp. 2549-2559. (doi: 10.1021/acsanm.2c04913) (PMCID:PMC9972347)
Ross, E. A. et al. (2023) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells. Nature Communications, 14, 753. (doi: 10.1038/s41467-023-36293-7) (PMID:36765065) (PMCID:PMC9918539)
Alqahtani, S., Butcher, M. C., Ramage, G. , Dalby, M. J. , McLean, W. and Nile, C. J. (2023) Acetylcholine receptors in mesenchymal stem cells. Stem Cells and Development, 32(3-4), pp. 47-59. (doi: 10.1089/scd.2022.0201) (PMID:36355611)
Marshall, W. G. et al. (2023) Bioengineering an osteoinductive treatment for bone healing disorders: a small animal case series. VCOT Open, 6(1), e41-e51. (doi: 10.1055/s-0043-1762900)
2022
Xiao, Y., Donnelly, H., Sprott, M. , Luo, J., Jayawarna, V., Lemgruber, L. , Tsimbouri, P. M. , Meek, R.M. D., Salmeron-Sanchez, M. and Dalby, M. J. (2022) Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis. Materials Today Bio, 16, 100367. (doi: 10.1016/j.mtbio.2022.100367) (PMID:35937570) (PMCID:PMC9352550)
Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biomaterials to engineer hematopoietic stem cell niches. Advanced Healthcare Materials, 11(20), 2200964. (doi: 10.1002/adhm.202200964) (PMID:35933595)
Luo, J., Walker, M. , Xiao, Y., Donnelly, H., Dalby, M. J. and Salmeron-Sanchez, M. (2022) The influence of nanotopography on cell behaviour through interactions with the extracellular matrix – a review. Bioactive Materials, 15, pp. 145-159. (doi: 10.1016/j.bioactmat.2021.11.024)
Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biointerfaces for the maintenance of mesenchymal stem cell phenotypes. Advanced Functional Materials, 32(32), 2203352. (doi: 10.1002/adfm.202203352)
Xiao, Y., McGuinness, C. A.S., Doherty-Boyd, W. S., Salmeron-Sanchez, M. , Donnelly, H. and Dalby, M. J. (2022) Current insights into the bone marrow niche: from biology in vivo to bioengineering ex vivo. Biomaterials, 286, 121568. (doi: 10.1016/j.biomaterials.2022.121568) (PMID:35580474)
Anderson, H. J., Sahoo, J. K., Wells, J., van Nuffel, S., Dhowre, H. S., Oreffo, R. O.C., Zelzer, M., Ulijn, R. V. and Dalby, M. J. (2022) Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation. Scientific Reports, 12, 8165. (doi: 10.1038/s41598-022-12057-z) (PMID:35581256) (PMCID:PMC9114122)
Dhawan, U. , Jaffery, H., Salmeron-Sanchez, M. and Dalby, M. J. (2022) An ossifying landscape: materials and growth factor strategies for osteogenic signalling and bone regeneration. Current Opinion in Biotechnology, 73, pp. 355-363. (doi: 10.1016/j.copbio.2021.10.010) (PMID:34735985)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
2021
Gavazzo, P., Viti, F., Donnelly, H., Oliva, M. A. G., Salmeron-Sanchez, M. , Dalby, M. J. and Vassalli, M. (2021) Biophysical phenotyping of mesenchymal stem cells along the osteogenic differentiation pathway. Cell Biology and Toxicology, 37(6), pp. 915-933. (doi: 10.1007/s10565-020-09569-7) (PMID:33420657)
Rodrigo-Navarro, A. , Sankaran, S., Dalby, M. J. , del Campo, A. and Salmeron-Sanchez, M. (2021) Engineered living biomaterials. Nature Reviews Materials, 6(12), pp. 1175-1190. (doi: 10.1038/s41578-021-00350-8)
Kennedy, J. W., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P. S., Meek, D. R. M., Goodyear, C. S. and Dalby, M. J. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. Scientific Reports, 11, 22741. (doi: 10.1038/s41598-021-02139-9)
Garner, S. J., Dalby, M. J. , Nobbs, A. H. and Barbour, M. E. (2021) A novel chlorhexidine-hexametaphosphate coating for titanium with antibiofilm efficacy and stem cell cytocompatibility. Journal of Materials Science: Materials in Medicine, 32(12), 139. (doi: 10.1007/s10856-021-06616-5)
Wei, D., Charlton, L., Glidle, A., Qi, N., Dobson, P. S. , Dalby, M. J. , Fan, H. and Yin, H. (2021) Dynamically modulated core-shell microfibers to study the effect of depth sensing of matrix stiffness on stem cell fate. ACS Applied Materials and Interfaces, 13(32), pp. 37997-38006. (doi: 10.1021/acsami.1c06752) (PMID:34355561)
Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)
Schofield, C. L., Rodrigo-Navarro, A. , Dalby, M. J. , Van Agtmael, T. and Salmeron-Sanchez, M. (2021) Biochemical– and biophysical–induced barriergenesis in the blood brain barrier: a review of barriergenic factors for use in in vitro models. Advanced NanoBiomed Research, 1(5), 2000068. (doi: 10.1002/anbr.202000068)
Barcelona Estaje, E., Dalby, M. J. , Cantini, M. and Salmeron-Sanchez, M. (2021) You talking to me? Cadherin and integrin crosstalk in biomaterials design. Advanced Healthcare Materials, 10(6), 2002048. (doi: 10.1002/adhm.202002048) (PMID:33586353)
Borrego-González, S., Dalby, M. J. and Díaz-Cuenca, A. (2021) Nanofibrous gelatin-based biomaterial with improved biomimicry using D-periodic self-assembled atelocollagen. Biomimetics, 6(1), 20. (doi: 10.3390/biomimetics6010020) (PMID:33803778) (PMCID:PMC8006151)
Sarrigiannidis, S. O., Rey, J. M., Dobre, O. , Gonzalez Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2021) A tough act to follow: collagen hydrogel modifications to improve mechanical and growth factor loading capabilities. Materials Today Bio, 10, 100098. (doi: 10.1016/j.mtbio.2021.100098) (PMID:33763641) (PMCID:PMC7973388)
Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)
2020
Trujillo, S. , Vega, S. L., Song, K. H., San Félix, A., Dalby, M. J. , Burdick, J. A. and Salmeron-Sanchez, M. (2020) Engineered full-length fibronectin-hyaluronic acid hydrogels for stem cell engineering. Advanced Healthcare Materials, 9(21), 2000989. (doi: 10.1002/adhm.202000989) (PMID:33002348)
Witte, K. , de Andrés, M. C., Wells, J., Dalby, M. J. , Salmeron-Sanchez, M. and Oreffo, R. O.C. (2020) Chondrobags: a high throughput alginate-fibronectin micromass platform for in vitro human cartilage formation. Biofabrication, 12(4), 045034. (doi: 10.1088/1758-5090/abb653)
Childs, P. G., Reid, S., Salmeron-Sanchez, M. and Dalby, M. J. (2020) Hurdles to uptake of mesenchymal stem cells and their progenitors in therapeutic products. Biochemical Journal, 477(17), pp. 3349-3366. (doi: 10.1042/BCJ20190382) (PMID:32941644) (PMCID:PMC7505558)
Trujillo Munoz, S. , Gonzalez Garcia, C., Rico Tortosa, P., Reid, A., Windmill, J., Dalby, M. J. and Salmeron-Sanchez, M. (2020) Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors. Biomaterials, 252, 120104. (doi: 10.1016/j.biomaterials.2020.120104)
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
Sarrigiannidis, S. O., Moussa, H., Dobre, O. , Dalby, M. J. , Tamimi, F. and Salmerón-Sánchez, M. (2020) Chiral tartaric acid improves fracture toughness of bioactive brushite-collagen bone cements. ACS Applied Bio Materials, 3(8), pp. 5056-5066. (doi: 10.1021/acsabm.0c00555) (PMID:32904797) (PMCID:PMC7461128)
Alba, A., Jayawarna, V., Childs, P. G., Dalby, M. J. and Salmeron-Sanchez, M. (2020) Plasma polymerised nanoscale coatings of controlled thickness for efficient solid-phase presentation of growth factors. Materials Science and Engineering C: Materials for Biological Applications, 113, 110966. (doi: 10.1016/j.msec.2020.110966) (PMID:32487385)
Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)
Cantini, M. , Donnelly, H., Dalby, M. J. and Salmeron-Sanchez, M. (2020) The plot thickens: the emerging role of matrix viscosity in cell mechanotransduction. Advanced Healthcare Materials, 9(8), 1901259. (doi: 10.1002/adhm.201901259) (PMID:31815372)
Huethorst, E. , Cutiongco, M. F.A. , Campbell, F. A., Saeed, A. , Love, R., Reynolds, P. M. , Dalby, M. J. and Gadegaard, N. (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12(2), 025009. (doi: 10.1088/1758-5090/ab5d3f) (PMID:31783378) (PMCID:PMC7655147)
2019
Campsie, P., Childs, P. G., Robertson, S. N., Cameron, K., Hough, J. , Salmeron-Sanchez, M. , Tsimbouri, P. M., Vichare, P., Dalby, M. J. and Reid, S. (2019) Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis. Scientific Reports, 9, 12944. (doi: 10.1038/s41598-019-49422-4) (PMID:31506561) (PMCID:PMC6736847)
Kareem, M. M., Hodgkinson, T., Salmeron-Sanchez, M. , Dalby, M. J. and Tanner, K. E. (2019) Hybrid core-shell scaffolds for bone tissue engineering. Biomedical Materials, 14(2), 025008. (doi: 10.1088/1748-605X/aafbf1) (PMID:30609417)
Sprott, M. R. , Gallego-Ferrer, G., Dalby, M. J. , Salmeron-Sanchez, M. and Cantini, M. (2019) Functionalisation of PLLA with polymer brushes to trigger the assembly of fibronectin into nanonetworks. Advanced Healthcare Materials, 8(3), 1801469. (doi: 10.1002/adhm.201801469) (PMID:30609243)
Cheng, Z. A. et al. (2019) Nanoscale coatings for ultralow dose BMP‐2‐driven regeneration of critical‐sized bone defects. Advanced Science, 6(2), 1800361. (doi: 10.1002/advs.201800361) (PMID:30693176) (PMCID:PMC6343071)
Mas-Moruno, C., Su, B. and Dalby, M. J. (2019) Multifunctional coatings and nanotopographies: towards cell instructive and antibacterial implants. Advanced Healthcare Materials, 8(1), 1801103. (doi: 10.1002/adhm.201801103) (PMID:30468010)
Trujillo, S. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2019) Mechanotransduction and growth factor signaling in hydrogel-based microenvironments. In: Encyclopedia of Tissue Engineering and Regenerative Medicine. Elsevier, pp. 87-101. ISBN 9780128137000 (doi: 10.1016/B978-0-12-801238-3.11141-9)
2018
Hay, J. J., Rodrigo-Navarro, A. , Petaroudi, M., Bryksin, A. V., Garcia, A. J., Barker, T. H., Dalby, M. J. and Salmeron-Sanchez, M. (2018) Bacteria-based materials for stem cell engineering. Advanced Materials, 30(43), 1804310. (doi: 10.1002/adma.201804310) (PMID:30209838)
Donnelly, H., Dalby, M. J. , Salmeron-Sanchez, M. and Sweeten, P. E. (2018) Current approaches for modulation of the nanoscale interface in the regulation of cell behavior. Nanomedicine: Nanotechnology, Biology and Medicine, 14(7), pp. 2455-2464. (doi: 10.1016/j.nano.2017.03.020) (PMID:28552647) (PMCID:PMC6173683)
Waddell, S. J., de Andrés, M. C., Tsimbouri, P. M. , Alakpa, E. V., Cusack, M., Dalby, M. J. and Oreffo, R. O.C. (2018) Biomimetic oyster shell-replicated topography alters the behaviour of human skeletal stem cells. Journal of Tissue Engineering, 9, p. 2041731418794007. (doi: 10.1177/2041731418794007) (PMID:30202512) (PMCID:PMC6124183)
Donnelly, H., Salmeron-Sanchez, M. and Dalby, M. J. (2018) Designing stem cell niches for differentiation and self-renewal. Journal of the Royal Society: Interface, 15(145), 20180388. (doi: 10.1098/rsif.2018.0388) (PMID:30158185) (PMCID:PMC6127175)
Robertson, S. N. et al. (2018) Control of cell behaviour through nanovibrational stimulation: nanokicking. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 376(2120), 20170290. (doi: 10.1098/rsta.2017.0290) (PMID:29661978) (PMCID:PMC5915650)
Spadaccio, C., Dalby, M. and Danton, M. H.D. (2018) Daytime variations in perioperative myocardial injury. Lancet, 391(10135), pp. 2105-2106. (doi: 10.1016/S0140-6736(18)30785-2) (PMID:29856342)
Moulisova, V. , Al-Jarsha, M., Leal-Egaña, A., Connell, A., Naudi, K. B., Ayoub, A. F. , Dalby, M. J. and Salmeron-Sanchez, M. (2018) Engineered coatings for titanium implants to present ultralow doses of BMP-7. ACS Biomaterials Science and Engineering, 4(5), pp. 1812-1819. (doi: 10.1021/acsbiomaterials.7b01037) (PMID:29862317) (PMCID:PMC5973637)
Casson, J., O'Kane, S., Smith, C.-A. , Dalby, M. J. and Berry, C. C. (2018) Interleukin 6 plays a role in the migration of magnetically levitated mesenchymal stem cells spheroids. Applied Sciences, 8(3), 412. (doi: 10.3390/app8030412)
Mccully, M., Conde, J., Baptista, P. V., Mullin, M., Dalby, M. J. and Berry, C. C. (2018) Nanoparticle-antagomiR based targeting of miR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells. PLoS ONE, 13(2), e0192562. (doi: 10.1371/journal.pone.0192562) (PMID:29444183) (PMCID:PMC5812622)
Dalby, M. J. , García, A. J. and Salmeron-Sanchez, M. (2018) Receptor control in mesenchymal stem cell engineering. Nature Reviews Materials, 3, 17091. (doi: 10.1038/natrevmats.2017.91)
Allan, C., Ker, A., Smith, C.-A. , Tsimbouri, P. , Borsoi, J., O'Neill, S., Gadegaard, N. , Dalby, M. J. and Meek, D. (2018) Osteoblast response to disordered nanotopography. Journal of Tissue Engineering, 9, pp. 1-7. (doi: 10.1177/2041731418784098) (PMID:30034770) (PMCID:PMC6048666)
Casson, J., Davies, O. G., Smith, C.-A. , Dalby, M. J. and Berry, C. C. (2018) Mesenchymal stem cell-derived extracellular vesicles may promote breast cancer cell dormancy. Journal of Tissue Engineering, 9, p. 2041731418810093. (doi: 10.1177/2041731418810093) (PMID:30627418) (PMCID:PMC6311537)
Damiati, L., Eales, M. G., Nobbs, A. H., Su, B., Tsimbouri, P. , Salmeron-Sanchez, M. and Dalby, M. J. (2018) Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants. Journal of Tissue Engineering, 9, pp. 1-16. (doi: 10.1177/2041731418790694) (PMID:30116518)
Harper, M. M., Connolly, M. L., Goldie, L., Irvine, E. J., Shaw, J. E., Jayawarna, V., Richardson, S. M., Dalby, M. J. , Lightbody, D. and Ulijn, R. V. (2018) Biogelx: cell culture on self-assembling peptide gels. In: Nilsson, B. L. and Doran, T. M. (eds.) Peptide Self-Assembly: Methods and Protocols. Series: Methods in molecular biology (1777). Humana Press: New York, NY, pp. 283-303. ISBN 9781493978090 (doi: 10.1007/978-1-4939-7811-3_18)
2017
Fraioli, R. et al. (2017) Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands. Scientific Reports, 7, 16363. (doi: 10.1038/s41598-017-16385-3) (PMID:29180787) (PMCID:PMC5703844)
Heydari, T., Heidari, M., Mashinchian, O., Wojcik, M., Xu, K., Dalby, M. J. , Mahmoudi, M. and Ejtehadi, M. R. (2017) Development of a virtual cell model to predict cell response to substrate topography. ACS Nano, 11(9), pp. 9084-9092. (doi: 10.1021/acsnano.7b03732) (PMID:28742318)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
Ballester-Beltrán, J., Trujillo Munoz, S. , Alakpa, E. V., Compañ, V., Gavara, R., Meek, D., West, C. C., Péault, B., Dalby, M. J. and Salmeron-Sanchez, M. (2017) Confined sandwichlike microenvironments tune myogenic differentiation. ACS Biomaterials Science and Engineering, 3(8), pp. 1710-1718. (doi: 10.1021/acsbiomaterials.7b00109) (PMID:28824958) (PMCID:PMC5558191)
Alakpa, E. V., Jayawarna, V., Burgess, K. E.V., West, C. C., Péault, B., Ulijn, R. V. and Dalby, M. J. (2017) Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels. Scientific Reports, 7, 6895. (doi: 10.1038/s41598-017-07255-z) (PMID:28761049) (PMCID:PMC5537289)
Alakpa, E. V., Burgess, K. E.V., Chung, P., Riehle, M. O. , Gadegaard, N. , Dalby, M. J. and Cusack, M. (2017) Nacre topography produces higher crystallinity in bone than chemically induced osteogenesis. ACS Nano, 11(7), pp. 6717-6727. (doi: 10.1021/acsnano.7b01044) (PMID:28665112)
Grigoriou, E. , Cantini, M. , Dalby, M.J. , Petersen, A. and Salmeron-Sanchez, M. (2017) Cell migration on material-driven fibronectin microenvironments. Biomaterials Science, 5(7), 1326. (doi: 10.1039/C7BM00333A) (PMID:28612879) (PMCID:PMC5858633)
Wei, D., Sun, J., Bolderson, J., Zhong, M., Dalby, M. J. , Cusack, M. , Yin, H. , Fan, H. and Zhang, X. (2017) Continuous fabrication and assembly of spatial cell-laden fibers for a tissue-like construct via a photolithographic-based microfluidic chip. ACS Applied Materials and Interfaces, 9(17), pp. 14606-14617. (doi: 10.1021/acsami.7b00078) (PMID:28157291)
Moulisová, V. , Gonzalez-Garcia, C., Cantini, M. , Rodrigo-Navarro, A. , Weaver, J., Costell, M., Sabater i Serra, R., Dalby, M. J. , García, A. J. and Salmerón-Sánchez, M. (2017) Engineered microenvironments for synergistic VEGF - integrin signalling during vascularization. Biomaterials, 126, pp. 61-74. (doi: 10.1016/j.biomaterials.2017.02.024) (PMID:28279265) (PMCID:PMC5354119)
Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)
Lewis, N. S., Lewis, E. E.L., Mullin, M., Wheadon, H. , Dalby, M. J. and Berry, C. C. (2017) Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence. Journal of Tissue Engineering, 8, pp. 1-11. (doi: 10.1177/2041731417704428) (PMID:28616152) (PMCID:PMC5460809)
Anderson, H., Llopis-Hernandez, V. , Sweeten, P., Donnelly, H., Gurden, R., Orapiriyakul, W., Salmeron-Sanchez, M. , Dalby, M.J. and Tsimbouri, M.P. (2017) Nanoscale surface cues and cell behaviour. In: Hashmi, S. (ed.) Reference Module in Materials Science and Materials Engineering. Elsevier. ISBN 9780128035818 (doi: 10.1016/B978-0-12-803581-8.10226-7)
Donnelly, H., Smith, C.-A. , Sweeten, P. E., Gadegaard, N. , Meek, D., D'Este, M., Mata, A., Eglin, D. and Dalby, M. J. (2017) Bone and cartilage differentiation of a single stem cell population driven by material interface. Journal of Tissue Engineering, 8, pp. 1-10. (doi: 10.1177/2041731417705615) (PMID:28567273) (PMCID:PMC5438107)
2016
Tsimbouri, P.M. , Fisher, L., Holloway, N., Sjostrom, T., Meek, R.M.D., Su, B. and Dalby, M.J. (2016) Osteogenic and bactericidal surfaces from hydrothermal titania nanowires on titanium substrates. Scientific Reports, 6, 36857. (doi: 10.1038/srep36857) (PMID:27857168) (PMCID:PMC5114696)
Tsimbouri, P.M. , Holloway, N., Fisher, L., Sjostrom, T., Nobbs, A.H., Meek, R.M.D., Su, B. and Dalby, M.J. (2016) Osteogenic and Bactericidal Surfaces from Hydrothermal Titania Nanowires on Titanium Substrates. The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016.
Young, P.S., Greer, A.I.M. , Tsimbouri, P.M. , Meek, R.M.D., Gadegaard, N. and Dalby, M.J. (2016) Precision-Engineered Nanotopographical Surfaces to Control Osteoclast Differentiation. In: The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016,
Lewis, E. E. L., Wheadon, H. , Lewis, N., Yang, J., Mullin, M., Hursthouse, A., Stirling, D., Dalby, M. J. and Berry, C. C. (2016) A quiescent, regeneration-responsive tissue engineered mesenchymal stem cell bone marrow niche model via magnetic levitation. ACS Nano, 10(9), pp. 8346-8354. (doi: 10.1021/acsnano.6b02841) (PMID:27602872)
Rico, P., Mnatsakanyan, H., Dalby, M. J. and Salmeron-Sanchez, M. (2016) Material-driven fibronectin assembly promotes maintenance of mesenchymal stem cell phenotypes. Advanced Functional Materials, 26(36), pp. 6563-6573. (doi: 10.1002/adfm.201602333)
Laing, S., Suriano, R., Lamprou, D. A., Smith, C.-A. , Dalby, M. J. , Mabbott, S., Faulds, K. and Graham, D. (2016) Thermoresponsive polymer micropatterns fabricated by dip-pen nanolithography for a Highly controllable substrate with potential cellular applications. ACS Applied Materials and Interfaces, 8(37), pp. 24844-24852. (doi: 10.1021/acsami.6b03860) (PMID:27572916)
Aguayo, S., Strange, A., Gadegaard, N. , Dalby, M.J. and Bozec, L. (2016) Influence of biomaterial nanotopography on the adhesive and elastic properties of Staphylococcus aureus cells. RSC Advances, 6(92), pp. 89347-89355. (doi: 10.1039/C6RA12504B)
Alakpa, E. et al. (2016) Tunable supramolecular hydrogels for selection of lineage guiding metabolites in stem cell cultures. Chem, 1(2), pp. 298-319. (doi: 10.1016/j.chempr.2016.07.001)
Llopis-Hernández, V. , Cantini, M. , González-García, C., Cheng, Z. A., Yang, J., Tsimbouri, P. M. , García, A. J., Dalby, M. J. and Salmerón-Sánchez, M. (2016) Material-driven fibronectin assembly for high-efficiency presentation of growth factors. Science Advances, 2(8), e1600188. (doi: 10.1126/sciadv.1600188) (PMID:27574702) (PMCID:PMC5001810)
Ngandu Mpoyi, E., Cantini, M. , Reynolds, P. M. , Gadegaard, N. , Dalby, M. J. and Salmerón-Sánchez, M. (2016) Protein adsorption as a key mediator in the nanotopographical control of cell behavior. ACS Nano, 10(7), pp. 6638-6647. (doi: 10.1021/acsnano.6b01649) (PMID:27391047) (PMCID:PMC4980054)
Roberts, J. N. et al. (2016) Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation. ACS Nano, 10(7), pp. 6667-6679. (doi: 10.1021/acsnano.6b01765) (PMID:27322014) (PMCID:PMC4963921)
Nikukar, H., Childs, P. G., Curtis, A. S., Martin, I. W. , Riehle, M. O. , Dalby, M. J. and Reid, S. (2016) Production of nanoscale vibration for stimulation of human mesenchymal stem cells. Journal of Biomedical Nanotechnology, 12(7), pp. 1478-1488. (doi: 10.1166/jbn.2016.2264)
Silverwood, R. K. et al. (2016) Analysis of osteoclastogenesis/osteoblastogenesis on nanotopographical titania surfaces. Advanced Healthcare Materials, 5(8), pp. 947-955. (doi: 10.1002/adhm.201500664) (PMID:26890261)
Childs, P. G., Boyle, C., Pemberton, G. D., Nikukar, H., Curtis, A. S.G., Henriquez, F. L., Dalby, M. J. and Reid, S. (2016) Use of nanoscale mechanical stimulation for control and manipulation of cell behaviour. Acta Biomaterialia, 34, pp. 159-168. (doi: 10.1016/j.actbio.2015.11.045) (PMID:6612418))
Anderson, H. J., Dalby, M. J. , Sahoo, J. and Uljin, R. (2016) Mesenchymal stem cell fate: applying biomaterials for control of stem cell behaviour. Frontiers in Bioengineering and Biotechnology, 4, 38. (doi: 10.3389/fbioe.2016.00038) (PMID:27242999) (PMCID:PMC4865671)
Stipetic, L. H., Dalby, M. J. , Davies, R. L. , Morton, F. r. , Ramage, G. and Burgess, K. (2016) A novel metabolomic approach used for the comparison of Staphylococcus aureus planktonic cells and biofilm samples. Metabolomics, 12, 75. (doi: 10.1007/s11306-016-1002-0) (PMID:27013931) (PMCID:PMC4783440)
Hay, J., Rodrigo-Navarro, A. , Hassi, K., Moulisova, V. , Dalby, M. J. and Salmeron-Sanchez, M. (2016) Living biointerfaces based on non-pathogenic bacteria support stem cell differentiation. Scientific Reports, 6, 21809. (doi: 10.1038/srep21809) (PMID:26902619) (PMCID:PMC4763179)
Bathawab, F., Bennett, M., Cantini, M. , Reboud, J. , Dalby, M. and Salmeron-Sanchez, M. (2016) Lateral chain length in polyalkyl acrylates determines the mobility of fibronectin at the cell/material interface. Langmuir, 32(3), pp. 800-809. (doi: 10.1021/acs.langmuir.5b03259) (PMID:26715432) (PMCID:PMC4732669)
Alfotawi, R., Ayoub, A. , Tanner, K. E. , Dalby, M. , Busuttil Naudi, K. and McMahon, J. (2016) A novel surgical approach for the reconstruction of critical-size mandibular defects using calcium sulphate/hydroxyapatite cement, BMP-7 and mesenchymal stem cells-histological assessment. Journal of Biomaterials and Tissue Engineering, 6(1), pp. 1-11. (doi: 10.1166/jbt.2016.1412)
Davison, M. J., McMurray, R. J., Smith, C.-A. , Dalby, M. and Meek, R.M. D. (2016) Nanopit-induced osteoprogenitor cell differentiation: the effect of nanopit death. Journal of Tissue Engineering, 7, pp. 1-8. (doi: 10.1177/2041731416652778) (PMID:27298716)
Salmeron-Sanchez, M. and Dalby, M. J. (2016) Synergistic growth factor microenvironments. Chemical Communications, 52(91), pp. 13327-13336. (doi: 10.1039/C6CC06888J) (PMID:27722261)
2015
Haggarty, J., Oppermann, M., Dalby, M. J. , Burchmore, R. J. , Cook, K., Weidt, S. and Burgess, K. E.V. (2015) Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome. Metabolomics, 11(5), pp. 1465-1470. (doi: 10.1007/s11306-014-0770-7) (PMID:26366140) (PMCID:PMC4559102)
Estévez, M., Martínez, E., Yarwood, S. J., Dalby, M. J. and Samitier, J. (2015) Adhesion and migration of cells responding to microtopography. Journal of Biomedical Materials Research Part A, 103(5), pp. 1659-1668. (doi: 10.1002/jbm.a.35293) (PMID:25089034)
Stipetic, L. H., Hamilton, G., Dalby, M. J. , Davies, R. L. , Meek, R.M. D., Ramage, G. , Smith, D. G.E. and Burgess, K. E.V. (2015) Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip. Genome Announcements, 3(2), e00336-15. (doi: 10.1128/genomeA.00336-15) (PMID:25931597) (PMCID:PMC4417693)
Ballester-Beltrán, J., Biggs, M., Dalby, M. , Salmeron-Sanchez, M. and Leal-Egana, A. (2015) Sensing the difference: the influence of anisotropic cues on cell behavior. Frontiers in Materials, 2, 39. (doi: 10.3389/fmats.2015.00039)
Chong, D.S.T., Turner, L.-A., Gadegaard, N. , Seifalian, A.M., Dalby, M.J. and Hamilton, G. (2015) Nanotopography and plasma treatment: redesigning the surface for vascular graft endothelialisation. European Journal of Vascular and Endovascular Surgery, 49(3), pp. 335-343. (doi: 10.1016/j.ejvs.2014.12.008) (PMID:25579872)
Johnstone, S. A., Liley, M., Dalby, M. J. and Barnett, S. C. (2015) Comparison of human olfactory and skeletal MSCs using osteogenic nanotopography to demonstrate bone-specific bioactivity of the surfaces. Acta Biomaterialia, 13, pp. 266-276. (doi: 10.1016/j.actbio.2014.11.027) (PMID:25463488)
Alakpa, E., Burgess, K., Chung, P., Dalby, M. and Cusack, M. (2015) Topographical Bridging Between Bone and Nacre. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden, 24-27th Jun 2015.
Alakpa, E. et al. (2015) Selection of Lineage Guiding Metabolites in Stem Cell Cultures. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden, 24-27th Jun 2015.
Dalby, M. J. and Biggs, M. J.P. (2015) Special focus on nanoscale regeneration. Nanomedicine, 10(5), pp. 677-680. (doi: 10.2217/nnm.15.34)
Mashinchian, O., Turner, L.-A., Dalby, M. J. , Laurent, S., Shokrgozar, M. A., Bonakdar, S., Imani, M. and Mahmoudi, M. (2015) Regulation of stem cell fate by nanomaterial substrates. Nanomedicine, 10(5), pp. 829-847. (doi: 10.2217/nnm.14.225) (PMID:25816883)
Nikukar, H., Reid, S., Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2015) Control of mesenchymal stem-cell fate by engineering the nanoenvironment. In: Baharvand, H. and Aghdami, N. (eds.) Stem-Cell Nanoengineering. Wiley Blackwell: Hoboken, NJ, pp. 205-221. ISBN 9781118540619 (doi: 10.1002/9781118540640.ch12)
Pemberton, G. D., Childs, P., Reid, S., Nikukar, H., Tsimbouri, M. , Gadegaard, N. , Curtis, A. S. and Dalby, M. J. (2015) Nanoscale stimulation of osteoblastogenesis from mesenchymal stem cells: nanotopography and nanokicking. Nanomedicine, 10(4), pp. 547-560. (doi: 10.2217/nnm.14.134) (PMID:25723089)
Tsimbouri, P. M. , McNamara, L. E., Alakpa, E. V., Dalby, M. J. and Turner, L.-A. (2015) Cell material interactions. In: van Blitterswijk, C. A. and de Boer, J. (eds.) Tissue Engineering. Elsevier, pp. 217-251. ISBN 9780124202108 (doi: 10.1016/B978-0-12-420145-3.00007-9)
Young, P.S., Tsimbouri, P.M. , Gadegaard, N. , Meek, R.M.D. and Dalby, M.J. (2015) Osteoclastogenesis/osteoblastogenesis using human bone marrow-derived cocultures on nanotopographical polymer surfaces. Nanomedicine, 10(6), pp. 949-957. (doi: 10.2217/nnm.14.146) (PMID:25867859)
2014
Halai, M., Ker, A., Meek, R.M. D., Nadeem, D., Sjostrom, T., Su, B., McNamara, L. E., Dalby, M. J. and Young, P. S. (2014) Scanning electron microscopical observation of an osteoblast/osteoclast co-culture on micropatterned orthopaedic ceramics. Journal of Tissue Engineering, 5, (doi: 10.1177/2041731414552114) (PMID:25383174) (PMCID:PMC4221946)
McNamara, L. E., Sjostrom, T., Seunarine, K., Meek, R.M. D., Su, B. and Dalby, M. J. (2014) Investigation of the limits of nanoscale filopodial interactions. Journal of Tissue Engineering, 5, p. 2041731414536177. (doi: 10.1177/2041731414536177) (PMID:24904726) (PMCID:PMC4046805)
Wang, J. R., Ahmed, S. F. , Gadegaard, N. , Meek, R.M. D., Dalby, M. J. and Yarwood, S. J. (2014) Nanotopology potentiates growth hormone signalling and osteogenesis of mesenchymal stem cells. Growth Hormone and IGF Research, 24(6), pp. 245-250. (doi: 10.1016/j.ghir.2014.10.003) (PMID:25466909)
Yang, J., McNamara, L. E., Gadegaard, N. , Alakpa, E. V., Burgess, K. V., Meek, D. and Dalby, M. J. (2014) Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs. ACS Nano, 8(10), pp. 9941-9953. (doi: 10.1021/nn504767g) (PMID:25227207)
Alfotawi, R., Ayoub, A. F. , Heath, N., Naudi, K. B., Tanner, K. E. , Dalby, M. J. and McMahon, J. (2014) Radiological assessment of bioengineered bone in a muscle flap for the reconstruction of critical-size mandibular defect. PLoS ONE, 9(9), e107403. (doi: 10.1371/journal.pone.0107403) (PMID:25226170) (PMCID:PMC4167331)
McMurray, R. J., Dalby, M. and Tsimbouri, P. M. (2014) Using biomaterials to study stem cell mechanotransduction, growth and differentiation. Journal of Tissue Engineering and Regenerative Medicine, 9(5), pp. 528-539. (doi: 10.1002/term.1957) (PMID:25370612)
Silverwood, R.K., Fairhurst, P., Tsimbouri, P. , Sjostrom, T., Young, P., Su, B., Meek, R.M.D. and Dalby, M. (2014) Analysis of Osteoclastogenesis/Osteoblastogenesis Using Human Bone Marrow Derived Co-Cultures on Nanotopographical Titania Surfaces. In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, UK, 28 Mar 2014,
Cassidy, J.W., Roberts, J.N. , Smith, C.-A. , Robertson, M., White, K., Biggs, M.J., Oreffo, R.O.C. and Dalby, M.J. (2014) Osteogenic lineage restriction by osteoprogenitors cultured on nanometric grooved surfaces – the role of focal adhesion maturation. Acta Biomaterialia, 10(2), pp. 651-660. (doi: 10.1016/j.actbio.2013.11.008) (PMID:24252447) (PMCID:PMC3907683)
Tsimbouri, P. , Gadegaard, N., Burgess, K., White, K., Reynolds, P. , Herzyk, P. , Oreffo, R. and Dalby, M.J. (2014) Nanotopographical effects on mesenchymal stem cell morphology and phenotype. Journal of Cellular Biochemistry, 115(2), pp. 380-390. (doi: 10.1002/jcb.24673) (PMID:24123223)
Alakpa, E., Burgess, K., Dalby, M. and Cusack, M. (2014) Investigating the 'Bone-Shell Divide': Pearl Oyster Shell Topography as a Means of Directing Stem Cell Behaviour. European Society for Biomaterials (ESB 2014), Liverpool, UK, 31st Aug–3rd Sep 2014. (Unpublished)
Dalby, M. J. , Gadegaard, N. and Oreffo, R. O.C. (2014) Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate. Nature Materials, 13(6), pp. 558-569. (doi: 10.1038/NMAT3980)
Mashinchian, O. et al. (2014) Cell-imprinted substrates act as an artificial niche for skin regeneration. ACS Applied Materials and Interfaces, 6(15), pp. 13280-13292. (doi: 10.1021/am503045b) (PMID:24967724)
McNamara, L. E., Dalby, M. J. and Tsimbouri, M. P. (2014) The use of microarrays and fluorescence in situ hybridization for the study of mechanotransduction from topography. Methods in Cell Biology, 119, pp. 293-309. (doi: 10.1016/B978-0-12-416742-1.00015-9) (PMID:24439291)
Turner, L.-A. and Dalby, M. (2014) Nanotopography – potential relevance in the stem cell niche. Biomaterials Science, 2(11), pp. 1574-1594. (doi: 10.1039/c4bm00155a)
2013
Dalby, M.J. , Lee, L.C., Yang, J., MacIntyre, A. and McCully, M. (2013) Hydrogel nanoparticles for drug delivery. Nanomedicine, 8(11), pp. 1744-1745.
Dalby, M.J. , Lee, L.C., Yang, J., MacIntyre, A. and McCully, M. (2013) Periodicity is important in stem cell response. Nanomedicine, 8(11), p. 1744.
Alfotawi, R., Busuttil Naudi, K., Dalby, M. , Tanner, K.E. , McMahon, J. and Ayoub, A. (2013) Assessment of cellular viability on calcium sulphate/hydroxyapatite injectable scaffolds. Journal of Tissue Engineering, 4, p. 204173. (doi: 10.1177/2041731413509645)
Seras-Franzoso, J., Peebo, K., Corchero, J.L., Tsimbouri, P.M. , Unzueta, U., Rinas, U., Dalby, M.J. , Vazquez, E., García-Fruitós, E. and Villaverde, A. (2013) A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs. Nanomedicine, 8(10), pp. 1587-1599. (doi: 10.2217/nnm.12.188)
Curtis, A. S.G., Reid, S., Martin, I. , Vaidyanathan, R., Smith, C.-A. , Nikukar, H. and Dalby, M. J. (2013) Cell interactions at the nanoscale: piezoelectric stimulation. IEEE Transactions on NanoBioscience, 12(3), pp. 247-254. (doi: 10.1109/TNB.2013.2257837) (PMID:23771395)
Kingham, E., White, K., Gadegaard, N. , Dalby, M.J. and Oreffo, R.O.C. (2013) Nanotopographical cues augment mesenchymal differentiation of human embryonic stem cells. Small, 9(12), pp. 2140-2151. (doi: 10.1002/smll.201202340)
Nikukar, H., Reid, S.W.J., Tsimbouri, P.M. , Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2013) Osteogenesis of mesenchymal stem cells by nanoscale mechanotransduction. ACS Nano, 7(3), pp. 2758-2767. (doi: 10.1021/nn400202j)
Wiejak, J., Tsimbouri, P. M. , Herzyk, P. , Dalby, M. J. , Hamilton, G. and Yarwood, S. J. (2013) Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves. Biomaterials, 34(8), pp. 1967-1979. (doi: 10.1016/j.biomaterials.2012.11.036) (PMID:23245923) (PMCID:PMC3543902)
Maclaine, S.E., McNamara, L.E., Bennett, A.J., Dalby, M.J. and Meek, R.M. (2013) Developments in stem cells: implications for future joint replacements. Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine, 227(3), pp. 275-283. (doi: 10.1177/0954411912471492)
Tsimbouri, P. M. , Murawski, K., Hamilton, G., Herzyk, P. , Oreffo, R. O.C., Gadegaard, N. and Dalby, M. J. (2013) A genomics approach in determining nanotopographical effects on MSC phenotype. Biomaterials, 34(9), pp. 2177-2184. (doi: 10.1016/j.biomaterials.2012.12.019) (PMID:23312853) (PMCID:PMC3573234)
Reynolds, P.M. , Pedersen, R.H., Stormonth-Darling, J., Dalby, M.J. , Riehle, M.O. and Gadegaard, N. (2013) Label-free segmentation of co-cultured cells on a nanotopographical gradient. Nano Letters, 13(2), pp. 570-576. (doi: 10.1021/nl304097p)
Sjöström, T., Brydone, A.S., Meek, R.M.D., Dalby, M.J. , Su, B. and McNamara, L.E. (2013) Titanium nanofeaturing for enhanced bioactivity of implanted orthopedic and dental devices. Nanomedicine, 8(1), pp. 89-104. (doi: 10.2217/NNM.12.177)
Alakpa, E., Jayawarna, V., Burgess, K., Ulijn, R. and Dalby, M. (2013) Combining Hydrogels With Tuned Stiffness and Metabolomics to Identify Small Molecules that Drive Mesenchymal Stem Cell Differentiation. European Materials Research Society (E-MRS), Strasbourg, France, 27-31 May 2013.
Seras-Franzoso, J., Tsimbouri, P.M. , Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J. (2013) Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces. Nanomedicine, 9(2), pp. 207-220. (doi: 10.2217/nnm.13.43) (PMID:23631503)
2012
Tsimbouri, P.M. , McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, P. , Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N. and Dalby, M.J. (2012) Using nanotopography and metabolomics to identify biochemical effectors of multipotency. ACS Nano, 6(11), pp. 10239-10249. (doi: 10.1021/nn304046m)
McNamara, L.E., Burchmore, R.J.S. , Riehle, M.O. , Herzyk, P. , Biggs, M.J.P., Wilkinson, C.D.W., Curtis, A.S.G. and Dalby, M.J. (2012) The role of microtopography in cellular mechanotransduction. Biomaterials, 33(10), pp. 2835-2847. (doi: 10.1016/j.biomaterials.2011.11.047)
Dalby, M.J. , Macintyre, A., Roberts, J.N. , Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Nanosubstrates to illustrate differential adhesion mechanisms to fibronectin and vitronectin. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Alakpa, E.V., Burgess, K., Jayawarna, V., Ulijn, R. and Dalby, M. (2012) Development of Biomaterials for Cellular Differentiation Using a Metabolomics Approach. 3rd TERMIS World Congress, Vienna, Austria, 5-8 Sep 2012. p. 238.
Alakpa, E., Jayarwarna, V., Burgess, K. and Dalby, M. (2012) Characterisation of peptide biomaterials & innate metabolites that direct stem cell differentiation in vitro. European Cell and Materials, 23(Sup 4), p. 50.
Alberdi, M.P., Dalby, M.J. , Rodriguez-Andres, J., Fazakerley, J.K., Kohl, A. and Bell-Sakyi, L. (2012) Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines. Ticks and Tick-borne Diseases, 3(3), pp. 137-146. (doi: 10.1016/j.ttbdis.2012.05.002)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L..L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) 3D patterned agarose hydrogels for investigation of precursor cells in differentiation and chemoattraction. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Nanoporous titanium substrates for osteogenesis. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Research Highlights. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Kuboki, T., Kantawong, F., Burchmore, R. , Dalby, M.J. and Kidoaki, S. (2012) 2D-DIGE proteomic analysis of mesenchymal stem cell cultured on the elasticity-tunable hydrogels. Cell Structure and Function, 37(2), pp. 127-139. (doi: 10.1247/csf.12012)
Maclaine, S.E., Gadhari, N., Pugin, R., Meek, R.M.D., Liley, M. and Dalby, M.J. (2012) Optimizing the osteogenicity of nanotopography using block co-polymer phase separation fabrication techniques. Journal of Orthopaedic Research, 30(8), pp. 1190-1197. (doi: 10.1002/jor.22076)
McNamara, L.E., Kantawong, F., Dalby, M.J. , Riehle, M.O. and Burchmore, R.J.S. (2012) Preventing and troubleshooting artefacts in saturation labelled fluorescence 2D difference gel electrophoresis (saturation DiGE). Proteomics, 11(24), pp. 4610-4621. (doi: 10.1002/pmic.201100135)
2011
McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)
McMurray, R.J., Gadegaard, N. , Tsimbouri, P.M. , Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nature Materials, 10(8), pp. 637-644. (doi: 10.1038/nmat3058) (PMID:21765399)
Kantawong, F., Robertson, M.E., Gadegaard, N. , Oreffo, R.O.C., Burchmore, R.J. and Dalby, M.J. (2011) Protein expression of STRO-1 cells in response to different topographic features. Journal of Tissue Engineering, 2011, 534603. (doi: 10.4061/2011/534603) (PMID:21772957) (PMCID:PMC3136090)
Wilkinson, A., Hewitt, R. N., McNamara, L. E., McCloy, D., Meek, R.M. D. and Dalby, M. J. (2011) Biomimetic microtopography to enhance osteogenesis in vitro. Acta Biomaterialia, 7(7), pp. 2919-2925. (doi: 10.1016/j.actbio.2011.03.026)
Brydone, A. S., Dalby, M. J. , Berry, C. C. , Dominic Meek, R.M. D. and McNamara, L. E. (2011) Grooved surface topography alters matrix-metalloproteinase production by human fibroblasts. Biomedical Materials, 6(3), 035005. (doi: 10.1088/1748-6041/6/3/035005) (PMID:21505230)
Kingham, E.J., Tsimbouri, P.M. , Gadegaard, N. , Dalby, M.J. and Oreffo, R.O.C. (2011) Nanotopography induced osteogenic differentiation of human stem cells. Bone, 48(Sup. 2), S108-S109. (doi: 10.1016/j.bone.2011.03.177)
Alakpa, E., Jayawarna, V., Burgess, K. and Dalby, M. (2011) Elucidating cellular reaction to biomaterial substrates using a metabolomics approach. European Cells and Materials, 22(Sup 3), p. 18.
Biggs, M. J.P., Richards, R. G. and Dalby, M. J. (2011) Using immuno-scanning electron microscopy for the observation of focal adhesion-substratum interactions at the nano- and microscale in S-phase cells. Methods in Molecular Biology, 695, pp. 53-60. (doi: 10.1007/978-1-60761-984-0_4)
Khokhar, A.Z., Tsimbouri, P.M. , Dalby, M.J. and Gadegaard, N. (2011) Development of ultra-hard stamps for titanium patterning. In: 37th International Conference on Micro and Nano Engineering: MNE 2011, Berlin, 19 - 23 September 2011,
McNamara, L.E., McMurray, R.J., Dalby, M.J. and Tsimbouri, P.M. (2011) Surfaces and Cell Behavior. Comprehensive Biomaterials, 4(409), pp. 115-126. (doi: 10.1016/B978-0-08-055294-1.00010-6)
Tsimbouri, P. , Gadegaard, N. , Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography. Histology and Histopathology: Cellular and Molecular Biology, 26(S1), 31.012.
Tsimbouri, P. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2011) Effects of nanotopography on cell adhesion, morphology and differentiation. European Cells and Materials, 22(S2), p. 14.
2010
Tanner, K.E. and Dalby, M.J. (2010) Guest editorial: special issue on bone tissue engineering. Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine, 224(12), i-iv. (doi: 10.1177/095441191022401201)
Biggs, M.J.P., Richards, R.G. and Dalby, M.J. (2010) Nanotopographical modification: a regulator of cellular function through focal adhesions. Nanomedicine: Nanotechnology, Biology and Medicine, 6(5), pp. 619-633. (doi: 10.1016/j.nano.2010.01.009)
Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Riehle, M.O. , Oreffo, R.O., Dalby, M.J. and Burchmore, R. (2010) Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells. Acta Biomaterialia, 6(9), pp. 3694-3703. (doi: 10.1016/j.actbio.2010.02.038)
McNamara, L.E., Dalby, M.J., Riehle, M.O. and Burchmore, R.J.S. (2010) Fluorescence two-dimensional difference gel electrophoresis for biomaterial applications. Journal of the Royal Society: Interface, 7(Sppl 1), S107-S118. (doi: 10.1098/rsif.2009.0177.focus)
Biggs, M.J.P. and Dalby, M.J. (2010) Focal adhesions in osteoneogenesis. Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine, 224(12), pp. 1441-1453. (doi: 10.1243/09544119JEIM775)
Chrzanowski, W., Abou Neel, E.A., Lee, K.Y., Bismarck, A., Young, A.M., Hart, A.D., Dalby, M.J. and Knowles, J.C. (2010) Tailoring Cell Behavior on Polymers by the Incorporation of Titanium Doped Phosphate Glass Filler. Advanced Biomaterials, 12(7), B298-B308. (doi: 10.1002/adem.200980083)
McMurray, R.J., Gadegaard, N. , Dalby, M.J. , Tsimbouri, P.M. , Maclaine, S., Meek, D., McNamara, L.E., Child, H. and Berry, C.C. (2010) Research highlights. Nanomedicine, 5(10), pp. 1495-1499. (doi: 10.2217/nnm.10.119)
McNamara, L.E., McMurray, R.J., Biggs, M.J.P., Kantawong, F., Oreffo, R.O.C. and Dalby, M.J. (2010) Nanotopographical Control of Stem Cell Differentiation. Journal of Tissue Engineering, 2010(Art 12), pp. 1-13. (doi: 10.4061/2010/120623)
McPhee, G., Dalby, M.J. , Riehle, M.O. and Yin, H. (2010) Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study. Medical and Biological Engineering and Computing, 48(10), (doi: 10.1007/s11517-010-0657-3)
2009
Kantawong, F., Burchmore, R.J.S. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Proteomic analysis of human osteoprogenitor response to disordered nanotopography. Journal of the Royal Society: Interface, (doi: 10.1098/rsif.2008.0447)
Biggs, M.J.P., Richards, R.G., Gadegaard, N. , McMurray, R.J., Affrosman, S., Wilkinson, C.D., Oreffo, R.O.C. and Dalby, M.J. (2009) Interactions with nanoscale topography: adhesion quantification and signal transduction in cells of osteogenic and multipotent lineage. Journal of Biomedical Materials Research Part A, 91A(1), pp. 195-208. (doi: 10.1002/jbm.a.32196)
Biggs, M.J.P., Richards, R.G., Gadegaard, N. , Wilkinson, C.D.W., Oreffo, R.O.C. and Dalby, M.J. (2009) The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells. Biomaterials, 30(28), pp. 5094-5103. (doi: 10.1016/j.biomaterials.2009.05.049)
Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Burchmore, R.J. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling. Biomaterials, 30(27), pp. 4723-4731. (doi: 10.1016/j.biomaterials.2009.05.040)
Rossi, L., Riehle, M.O. , McNamara, L.E., Burchmore, R. , Dalby, M.J. , McMurray, R.J., Gadegaard, N. , Ahmed, S. and Tsimbouri, P.M. (2009) Research highlights. Nanomedicine, 4(6), pp. 613-617. (doi: 10.2217/nnm.09.46)
Kantawong, F., Burchmore, R.J.S., Wilkinson, C.D.W., Oreffo, R.O.C. and Dalby, M.J. (2009) Differential in-gel electrophoresis (DIGE) analysis of human bone marrow osteoprogenitor cell contact guidance. Acta Biomaterialia, 5(4), pp. 1137-1146. (doi: 10.1016/j.actbio.2008.11.001)
Dalby, M.J. (2009) Nanostructured surfaces: cell engineering and cell biology. Nanomedicine, 4(3), pp. 247-248. (doi: 10.2217/nnm.09.1)
Sjostrom, T., Dalby, M.J. , Hart, A., Tare, R., Oreffo, R.O.C. and Su, B. (2009) Fabrication of pillar-like titania nanostructures on titanium and their interactions with human skeletal stem cells. Acta Biomaterialia, 5(5), pp. 1433-1441. (doi: 10.1016/j.actbio.2009.01.007)
2008
Dalby, M.J. , McNamara, L.E., Riehle, M.O. , Burchmore, R.J.S. , Kuntanawat, P., McMurray, R.J., Gadegaard, N. and Andar, A. (2008) Research highlights. Nanomedicine, 3(4), pp. 411-414. (doi: 10.2217/17435889.3.4.411)
Dalby, M.J., Hart, A. and Yarwood, S.J. (2008) The effect of the RACK1 signalling protein on the regulation of cell adhesion and cell contact guidance on nanometric grooves. Biomaterials, 29(3), pp. 282-289. (doi: 10.1016/j.biomaterials.2007.09.030)
Biggs, M.J., Richards, R.G., Wilkinson, C.D. and Dalby, M.J. (2008) Focal adhesion interactions with topographical structures: a novel method for immuno-SEM labelling of focal adhesions in S-phase cells. Journal of Microscopy, 231(1), pp. 28-37. (doi: 10.1111/j.1365-2818.2008.02013.x)
Biggs, M.J.P., Richards, R.G., McFarlane, S., Wilkinson, C.D.W., Oreffo, R.O.C. and Dalby, M.J. (2008) Adhesion formation of primary human osteoblasts and the functional response of mesenchymal stem cells to 330nm deep microgrooves. Journal of the Royal Society: Interface, (doi: 10.1098/rsif.2008.0035)
Dalby, M.J. , Andar, A., Nag, A., Affrosman, S., Tare, R., McFarlane, S. and Oreffo, R.O.C. (2008) Genomic expression of mesenchymal stem cells to altered nanoscale topographies. Journal of the Royal Society: Interface, 5(26), pp. 1055-1065. (doi: 10.1098/rsif.2008.0016)
Dalby, M.J. , Gadegaard, N. and Wilkinson, C.D.W. (2008) The response of fibroblasts to hexagonal nanotopography fabricated by electron beam lithography. Journal of Biomedical Materials Research Part A, 84A(4), pp. 973-979. (doi: 10.1002/jbm.a.31409)
Gadegaard, N. , Dalby, M.J. , Riehle, M.O. and Wilkinson, C.D.W. (2008) Optimizing substrate disorder for bone tissue engineering of mesenchymal stem cells. Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures, 26(6), pp. 2554-2557. (doi: 10.1116/1.2978407)
2007
Kantawong, F., Dalby, M. and Burchmore, R. (2007) Differential proteomics evaluation of osteoprogenitor growth on microgrooved surfaces using bioreactor culture. Comparative Biochemistry and Physiology. Part A: Molecular and Integrative Physiology, 146(4), S192. (doi: 10.1016/j.cbpa.2007.01.420)
Biggs, M.J.P., Richards, R.G., Gadegaard, N. , Wilkinson, C.D.W. and Dalby, M.J. (2007) The effects of nanoscale pits on primary human osteoblast adhesion formation and cellular spreading. Journal of Materials Science: Materials in Medicine, 18, pp. 399-404. (doi: 10.1007/s10856-006-0705-6)
Biggs, M.J.P., Richards, R.G., Gadegaard, N. , Wilkinson, C.D.W. and Dalby, M.J. (2007) Regulation of implant surface cell adhesion: Characterization and quantification of S-phase primary osteoblast adhesions on biomimetic nanoscale substrates. Journal of Orthopaedic Research, 25, pp. 273-282. (doi: 10.1002/jor.20319)
Dalby, M.J. (2007) The beta integrins and cytoskeletal nanoimprinting. Experimental Cell Research, 314(4), pp. 927-935. (doi: 10.1016/j.yexcr.2007.10.003)
Dalby, M.J. (2007) Cellular response to low adhesion nanotopographies. International Journal of Nanomedicine, 2(3), pp. 373-381.
Dalby, M.J. (2007) Nanotopographical control of human osteoprogenitor differentiation. Current Stem Cell Research and Therapy, 2(2), pp. 129-138.
Dalby, M.J. , Biggs, M.J.P., Gadegaard, N. , Kalna, G., Wilkinson, C.D.W. and Curtis, A.S.G. (2007) Nanotopographical stimulation of mechanotransduction and changes in interphase centromere positioning. Journal of Cellular Biochemistry, 100, pp. 326-338. (doi: 10.1002/jcb.21058)
Dalby, M.J. , Gadegaard, N. , Herzyk, P. , Agheli, H., Sutherland, D.S. and Wilkinson, C.D.W. (2007) Group analysis of regulation of fibroblast genome on low-adhesion nanostructures. Biomaterials, 28, pp. 1761-1769. (doi: 10.1016/j.biomaterials.2006.11.049)
Dalby, M.J. , Gadegaard, N. , Tare, R., Andar, A., Riehle, M.O. , Herzyk, P. , Wilkinson, C.D.W. and Oreffo, R.O.C. (2007) The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nature Materials, 6(12), pp. 997-1003. (doi: 10.1038/nmat2013)
Hart, A., Gadegaard, N., Wilkinson, C., Oreffo, R. and Dalby, M. (2007) Osteoprogenitor response to low-adhesion nanotopographies originally fabricated by electron beam lithography. Journal of Materials Science: Materials in Medicine, 18, pp. 1211-1218. (doi: 10.1007/s10856-007-0157-7)
2006
Berry, C.C. , Dalby, M.J., Oreffo, R.O.C., McCloy, D. and Affrosman, S. (2006) The interaction of human bone marrow cells with nanotopographical features in three dimensional constructs. Journal of Biomedical Materials Research Part A, 79A, pp. 431-439. (doi: 10.1002/jbm.a.30960)
Curtis, A.S.G., Dalby, M.J. and Gadegaard, N. (2006) Cell signaling arising from nanotopography: implications for nanomedical devices. Nanomedicine, 1, pp. 67-72. (doi: 10.2217/17435889.1.1.67)
Curtis, A., Dalby, M. and Gadegaard, N. (2006) Nanoprinting onto cells. Journal of the Royal Society: Interface, 3, pp. 393-398. (doi: 10.1098/rsif.2005.0104)
Dalby, M.J. , McCloy, D., Robertson, M., Agheli, H., Sutherland, D., Affrossman, S. and Oreffo, R.O.C. (2006) Osteoprogenitor response to semi-ordered and random nanotopographies. Biomaterials, 27(15), pp. 2980-2987. (doi: 10.1016/j.biomaterials.2006.01.010)
Dalby, M., McCloy, D., Robertson, M., Wilkinson, C. and Oreffo, R. (2006) Osteoprogenitor response to defined topographies with nanoscale depths. Biomaterials, 27, pp. 1306-1315. (doi: 10.1016/j.biomaterials.2005.08.028)
2005
Berry, C., Dalby, M., McCloy, D. and Affrossman, S. (2005) The fibroblast response to tubes exhibiting internal nanotopography. Biomaterials, 26, pp. 4985-4992. (doi: 10.1016/j.biomaterials.2005.01.046)
Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2005) Morphological and microarray analysis of human fibroblasts cultured on nanocolumns produced by colloidal lithography. European Cells and Materials, 9, pp. 1-8.
Dalby, M. (2005) Topographically induced direct cell mechanotransduction. Medical Engineering and Physics, 27, pp. 730-742. (doi: 10.1016/j.medengphy.2005.04.005)
2004
Gadegaard, N. , Dalby, M.J. , Riehle, M.O. , Curtis, A.S.G. and Affrossman, S. (2004) Tubes with controllable internal nanotopography. Advanced Materials, 20, pp. 1857-1860. (doi: 10.1002/adma.200400408)
Dalby, M.J. , Gadegaard, N. , Riehle, M.O. , Wilkinson, C.D.W. and Curtis, A.S.G. (2004) Investigating filopodia sensing using arrays of defined nano-pits down to 35 nm diameter in size. International Journal of Biochemistry and Cell Biology, 36(10), pp. 2005-2015. (doi: 10.1016/j.biocel.2004.03.001)
Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Changes in fibroblast morphology in response to nano-columns produced by colloidal lithography. Biomaterials, 25(23), pp. 5415-5422. (doi: 10.1016/j.biomaterials.2003.12.049) (PMID:15130726)
Dalby, M.J. , Berry, C.C. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Attempted endocytosis of nano-environment produced by colloidal lithography by human fibroblasts. Experimental Cell Research, 295(2), pp. 387-394. (doi: 10.1016/j.yexcr.2004.02.004)
Dalby, M.J. , Pasqui, D. and Affrossman, S. (2004) Cell response to nano-islands produced by polymer demixing: a brief review. IEE Proceedings: Nanobiotechnology, 151(2), pp. 53-61. (doi: 10.1049/ip-nbt:20040534)
Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Fibroblast response to a controlled nanoenvironment produced by colloidal lithography. Journal of Biomedical Materials Research Part A, 69A(2), pp. 314-322. (doi: 10.1002/jbm.a.20138)
Berry, C.C. , Charles, S., Wells, S., Dalby, M.J. and Curtis, A.S.G. (2004) The influence of transferrin stabilised magnetic nanoparticles on human dermal fibroblasts in culture. International Journal of Pharmaceutics, 269(1), pp. 211-225. (doi: 10.1016/j.ijpharm.2003.09.042)
Dalby, M.J. , Giannaras, D., Riehle, M.O. , Gadegaard, N. , Affrossman, S. and Curtis, A.S.G. (2004) Rapid fibroblast adhesion to 27 nm high polymer demixed nano-topography. Biomaterials, 25(1), pp. 77-83. (doi: 10.1016/S0142-9612(03)00475-7)
Curtis, A.S.G., Gadegaard, N. , Dalby, M.J. , Riehle, M.O. , Wilkinson, C.D.W. and Aitchison, G. (2004) Cells react to nanoscale order and symmetry in their surroundings. IEEE Transactions on NanoBioscience, 3(1), pp. 61-65. (doi: 10.1109/TNB.2004.824276)
Dalby, M.J. , Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A.S.G. (2004) Investigating the limits of filopodial sensing: a brief report using SEM to image the interaction between 10 nm high nano-topography and fibroblast filopodia. Cell Biology International, 28(3), pp. 229-236. (doi: 10.1016/j.cellbi.2003.12.004)
Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Use of nanotopography to study mechanotransduction in fibroblasts – methods and perspectives. European Journal of Cell Biology, 83(4), pp. 159-169. (doi: 10.1078/0171-9335-00369)
2003
Dalby, M.J. , Riehle, M.O. , Johnstone, H.J.H., Affrossman, S. and Curtis, A.S.G. (2003) Nonadhesive nanotopography: fibroblast response to poly(n-butyl methacrylate)-poly(styrene) demixed surface features. Journal of Biomedical Materials Research Part A, 67A(3), pp. 1025-1032. (doi: 10.1002/jbm.a.10139)
Dalby, M.J. , Riehle, M.O. , Yarwood, S.J., Wilkinson, C.D.W. and Curtis, A.S.G. (2003) Nucleus alignment and cell signaling in fibroblasts: response to a micro-grooved topography. Experimental Cell Research, 284(2), pp. 272-280. (doi: 10.1016/S0014-4827(02)00053-8)
da Silva, M.H.P., Soares, G.D.A., Elias, C.N., Best, S.M., Gibson, I.R., Disilvio, L. and Dalby, M.J. (2003) In vitro cellular response to titanium electrochemically coated with hydroxyapatite compared to titanium with three different levels of surface roughness. Journal of Materials Science: Materials in Medicine, 14, pp. 511-519.
Dalby, M. (2003) Enhanced HAPEX topography: Comparison of osteoblast response to established cement. Journal of Materials Science: Materials in Medicine, 14(8), pp. 693-696. (doi: 10.1023/A:1024959632082)
Dalby, M., Childs, S., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2003) Fibroblast reaction to island topography: changes in cytoskeleton and morphology with time. Biomaterials, 24, pp. 927-935.
Opara, T., Dalby, M. , Harper, E., Di Silvio, L. and Bonfield, W. (2003) The effect of varying percentage hydroxyapatite in poly(ethylmethacrylate) bone cement on human osteoblast-like cells. Journal of Materials Science: Materials in Medicine, 14, pp. 277-282.
Riehle, M.O. , Dalby, M.J., Johnstone, H., MacIntosh, A. and Affrossman, S. (2003) Cell behaviour of rat calvaria bone cells on surfaces with random nanometric features. Materials Science and Engineering C: Biomimetic and Supramolecular Systems, 23(3), pp. 337-340. (doi: 10.1016/S0928-4931(02)00282-5)
2002
Dalby, M. (2002) New acrylic bone cements conjugated to vitamin E: Curing parameters, properties, and biocompatibility. Journal of Biomedical Materials Research Part A, 62(2), pp. 299-307. (doi: 10.1002/jbm.10296)
Dalby, M.J. , Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2002) Polymer-demixed nanotopography: Control of fibroblast spreading and proliferation. Tissue Engineering, 8, pp. 1099-1108.
Dalby, M. , Di Silvio, L., Gurav, N., Annaz, B., Kayser, M. and Bonfield, W. (2002) Optimizing HAPEX (TM) topography influences osteoblast response. Tissue Engineering, 8, pp. 453-467.
Dalby, M. , Di Silvio, L., Harper, E. and Bonfield, W. (2002) In vitro adhesion and biocompatability of osteoblast-like cells to poly(methylmethacrylate) and poly(ethylmethacrylate) bone cements. Journal of Materials Science: Materials in Medicine, 13, pp. 311-314.
Dalby, M. , Di Silvio, L., Harper, E. and Bonfield, W. (2002) Increasing hydroxyapatite incorporation into poly(methylmethacrylate) cement increases osteoblast adhesion and response. Biomaterials, 23, pp. 569-576.
Dalby, M. , Kayser, M., Bonfield, W. and Di Silvio, L. (2002) Initial attachment of osteoblasts to an optimised HAPEX (TM) topography. Biomaterials, 23, pp. 681-690.
Dalby, M., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2002) In vitro reaction of endothelial cells to polymer demixed nanotopography. Biomaterials, 23, pp. 2945-2954.
Dalby, M., Yarwood, S., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtsi, A. (2002) Increasing fibroblast response to materials using nanotopography: morphological and genetic measurements of cell response to 13-nm-high polymer demixed islands. Experimental Cell Research, 276, pp. 1-9. (doi: 10.1006/EXCR.2002.5498)
Di Silvio, L., Dalby, M. and Bonfield, W. (2002) Osteoblast behaviour on HA/PE composite surfaces with different HA volumes. Biomaterials, 23, pp. 101-107.
2001
Dalby, M. , Di Silvio, L., Harper, E. and Bonfield, W. (2001) Initial interaction of osteoblasts with the surface of a hydroxyapatite-poly(methylmethacrylate) cement. Biomaterials, 22, pp. 1739-1747.
Articles
Cuahtecontzi Delint, R., Jaffery, H., Ishak, M. I., Nobbs, A. H., Su, B. and Dalby, M. J. (2024) Mechanotransducive surfaces for enhanced cell osteogenesis, a review. Biomaterials Advances, (doi: 10.1016/j.bioadv.2024.213861) (In Press)
Dhawan, U. , Williams, J. A., Windmill, J. F.C., Childs, P., Gonzalez-Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2024) Engineered surfaces that promote capture of latent proteins to facilitate integrin-mediated mechanical activation of growth factors. Advanced Materials, (doi: 10.1002/adma.202310789) (PMID:38253339) (Early Online Publication)
Busch, C., Mulholland, T., Zagnoni, M., Dalby, M. , Berry, C. and Wheadon, H. (2023) Overcoming BCR::ABL1 dependent and independent survival mechanisms in chronic myeloid leukaemia using a multi-kinase targeting approach. Cell Communication and Signaling, 21, 342. (doi: 10.1186/s12964-023-01363-2) (PMID:38031192) (PMCID:PMC10685629)
Sanchez-Rubio, A., Jayawarna, V., Maxwell, E., Dalby, M. J. and Salmeron-Sanchez, M. (2023) Keeping it organized: multicompartment constructs to mimic tissue heterogeneity. Advanced Healthcare Materials, 12(17), 2202110. (doi: 10.1002/adhm.202202110) (PMID:36938891)
Dhawan, U. , Wang, W.-L., Lin, Y.-C., Yang, R.-B., Dalby, M. J. , Salmeron-Sanchez, M. and Yu, H.-h. (2023) Mechanostimulation-induced integrin αvβ6 and latency associated peptide coupling activates TGF-β and regulates cancer metastasis and stemness. Nano Today, 50, 101882. (doi: 10.1016/j.nantod.2023.101882)
Sarrigiannidis, S. O., Dobre, O. , Navarro, A. R., Dalby, M. J. , Gonzalez-Garcia, C. and Salmeron-Sanchez, M. (2023) Engineered dual affinity protein fragments to bind collagen and capture growth factors. Materials Today Bio, 20, 100641. (doi: 10.1016/j.mtbio.2023.100641) (PMID:37179535) (PMCID:PMC10173277)
Sonam, S., Malmstrom, J., Kamei, K.-i. and Dalby, M. J. (2023) Editorial: Materials for mechanotransduction and beyond. Frontiers in Cell and Developmental Biology, 11, 1222957. (doi: 10.3389/fcell.2023.1222957) (PMID:37305678) (PMCID:PMC10250702)
Donnelly, H., Kurjan, A., Yong, L. Y., Xiao, Y., Lemgruber, L. , West, C., Salmeron-Sanchez, M. and Dalby, M. J. (2023) Fibronectin matrix assembly and TGFβ1 presentation for chondrogenesis of patient derived pericytes for microtia repair. Biomaterials Advances, 148, 213370. (doi: 10.1016/j.bioadv.2023.213370) (PMID:36931082)
Ishak, M. I., Eales, M., Damiati, L., Liu, X., Jenkins, J., Dalby, M. J. , Nobbs, A. H., Ryadnov, M. G. and Su, B. (2023) Enhanced and stem-cell-compatible effects of nature-inspired antimicrobial nanotopography and antimicrobial peptides to combat implant-associated infection. ACS Applied Nano Materials, 6(4), pp. 2549-2559. (doi: 10.1021/acsanm.2c04913) (PMCID:PMC9972347)
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Alqahtani, S., Butcher, M. C., Ramage, G. , Dalby, M. J. , McLean, W. and Nile, C. J. (2023) Acetylcholine receptors in mesenchymal stem cells. Stem Cells and Development, 32(3-4), pp. 47-59. (doi: 10.1089/scd.2022.0201) (PMID:36355611)
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Xiao, Y., Donnelly, H., Sprott, M. , Luo, J., Jayawarna, V., Lemgruber, L. , Tsimbouri, P. M. , Meek, R.M. D., Salmeron-Sanchez, M. and Dalby, M. J. (2022) Material-driven fibronectin and vitronectin assembly enhances BMP-2 presentation and osteogenesis. Materials Today Bio, 16, 100367. (doi: 10.1016/j.mtbio.2022.100367) (PMID:35937570) (PMCID:PMC9352550)
Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biomaterials to engineer hematopoietic stem cell niches. Advanced Healthcare Materials, 11(20), 2200964. (doi: 10.1002/adhm.202200964) (PMID:35933595)
Luo, J., Walker, M. , Xiao, Y., Donnelly, H., Dalby, M. J. and Salmeron-Sanchez, M. (2022) The influence of nanotopography on cell behaviour through interactions with the extracellular matrix – a review. Bioactive Materials, 15, pp. 145-159. (doi: 10.1016/j.bioactmat.2021.11.024)
Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2022) Living biointerfaces for the maintenance of mesenchymal stem cell phenotypes. Advanced Functional Materials, 32(32), 2203352. (doi: 10.1002/adfm.202203352)
Xiao, Y., McGuinness, C. A.S., Doherty-Boyd, W. S., Salmeron-Sanchez, M. , Donnelly, H. and Dalby, M. J. (2022) Current insights into the bone marrow niche: from biology in vivo to bioengineering ex vivo. Biomaterials, 286, 121568. (doi: 10.1016/j.biomaterials.2022.121568) (PMID:35580474)
Anderson, H. J., Sahoo, J. K., Wells, J., van Nuffel, S., Dhowre, H. S., Oreffo, R. O.C., Zelzer, M., Ulijn, R. V. and Dalby, M. J. (2022) Cell-controlled dynamic surfaces for skeletal stem cell growth and differentiation. Scientific Reports, 12, 8165. (doi: 10.1038/s41598-022-12057-z) (PMID:35581256) (PMCID:PMC9114122)
Dhawan, U. , Jaffery, H., Salmeron-Sanchez, M. and Dalby, M. J. (2022) An ossifying landscape: materials and growth factor strategies for osteogenic signalling and bone regeneration. Current Opinion in Biotechnology, 73, pp. 355-363. (doi: 10.1016/j.copbio.2021.10.010) (PMID:34735985)
Damiati, L. A. et al. (2022) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. Biomaterials, 280, 121263. (doi: 10.1016/j.biomaterials.2021.121263) (PMID:34810036)
Gavazzo, P., Viti, F., Donnelly, H., Oliva, M. A. G., Salmeron-Sanchez, M. , Dalby, M. J. and Vassalli, M. (2021) Biophysical phenotyping of mesenchymal stem cells along the osteogenic differentiation pathway. Cell Biology and Toxicology, 37(6), pp. 915-933. (doi: 10.1007/s10565-020-09569-7) (PMID:33420657)
Rodrigo-Navarro, A. , Sankaran, S., Dalby, M. J. , del Campo, A. and Salmeron-Sanchez, M. (2021) Engineered living biomaterials. Nature Reviews Materials, 6(12), pp. 1175-1190. (doi: 10.1038/s41578-021-00350-8)
Kennedy, J. W., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P. S., Meek, D. R. M., Goodyear, C. S. and Dalby, M. J. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. Scientific Reports, 11, 22741. (doi: 10.1038/s41598-021-02139-9)
Garner, S. J., Dalby, M. J. , Nobbs, A. H. and Barbour, M. E. (2021) A novel chlorhexidine-hexametaphosphate coating for titanium with antibiofilm efficacy and stem cell cytocompatibility. Journal of Materials Science: Materials in Medicine, 32(12), 139. (doi: 10.1007/s10856-021-06616-5)
Wei, D., Charlton, L., Glidle, A., Qi, N., Dobson, P. S. , Dalby, M. J. , Fan, H. and Yin, H. (2021) Dynamically modulated core-shell microfibers to study the effect of depth sensing of matrix stiffness on stem cell fate. ACS Applied Materials and Interfaces, 13(32), pp. 37997-38006. (doi: 10.1021/acsami.1c06752) (PMID:34355561)
Dobre, O. et al. (2021) A hydrogel platform that incorporates laminin isoforms for efficient presentation of growth factors – neural growth and osteogenesis. Advanced Functional Materials, 31(21), 2010225. (doi: 10.1002/adfm.202010225)
Schofield, C. L., Rodrigo-Navarro, A. , Dalby, M. J. , Van Agtmael, T. and Salmeron-Sanchez, M. (2021) Biochemical– and biophysical–induced barriergenesis in the blood brain barrier: a review of barriergenic factors for use in in vitro models. Advanced NanoBiomed Research, 1(5), 2000068. (doi: 10.1002/anbr.202000068)
Barcelona Estaje, E., Dalby, M. J. , Cantini, M. and Salmeron-Sanchez, M. (2021) You talking to me? Cadherin and integrin crosstalk in biomaterials design. Advanced Healthcare Materials, 10(6), 2002048. (doi: 10.1002/adhm.202002048) (PMID:33586353)
Borrego-González, S., Dalby, M. J. and Díaz-Cuenca, A. (2021) Nanofibrous gelatin-based biomaterial with improved biomimicry using D-periodic self-assembled atelocollagen. Biomimetics, 6(1), 20. (doi: 10.3390/biomimetics6010020) (PMID:33803778) (PMCID:PMC8006151)
Sarrigiannidis, S. O., Rey, J. M., Dobre, O. , Gonzalez Garcia, C., Dalby, M. J. and Salmeron-Sanchez, M. (2021) A tough act to follow: collagen hydrogel modifications to improve mechanical and growth factor loading capabilities. Materials Today Bio, 10, 100098. (doi: 10.1016/j.mtbio.2021.100098) (PMID:33763641) (PMCID:PMC7973388)
Hodgkinson, T. et al. (2021) The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells. Science Advances, 7(9), eabb7921. (doi: 10.1126/sciadv.abb7921) (PMID:33637520) (PMCID:PMC7909882)
Trujillo, S. , Vega, S. L., Song, K. H., San Félix, A., Dalby, M. J. , Burdick, J. A. and Salmeron-Sanchez, M. (2020) Engineered full-length fibronectin-hyaluronic acid hydrogels for stem cell engineering. Advanced Healthcare Materials, 9(21), 2000989. (doi: 10.1002/adhm.202000989) (PMID:33002348)
Witte, K. , de Andrés, M. C., Wells, J., Dalby, M. J. , Salmeron-Sanchez, M. and Oreffo, R. O.C. (2020) Chondrobags: a high throughput alginate-fibronectin micromass platform for in vitro human cartilage formation. Biofabrication, 12(4), 045034. (doi: 10.1088/1758-5090/abb653)
Childs, P. G., Reid, S., Salmeron-Sanchez, M. and Dalby, M. J. (2020) Hurdles to uptake of mesenchymal stem cells and their progenitors in therapeutic products. Biochemical Journal, 477(17), pp. 3349-3366. (doi: 10.1042/BCJ20190382) (PMID:32941644) (PMCID:PMC7505558)
Trujillo Munoz, S. , Gonzalez Garcia, C., Rico Tortosa, P., Reid, A., Windmill, J., Dalby, M. J. and Salmeron-Sanchez, M. (2020) Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors. Biomaterials, 252, 120104. (doi: 10.1016/j.biomaterials.2020.120104)
Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)
Sarrigiannidis, S. O., Moussa, H., Dobre, O. , Dalby, M. J. , Tamimi, F. and Salmerón-Sánchez, M. (2020) Chiral tartaric acid improves fracture toughness of bioactive brushite-collagen bone cements. ACS Applied Bio Materials, 3(8), pp. 5056-5066. (doi: 10.1021/acsabm.0c00555) (PMID:32904797) (PMCID:PMC7461128)
Alba, A., Jayawarna, V., Childs, P. G., Dalby, M. J. and Salmeron-Sanchez, M. (2020) Plasma polymerised nanoscale coatings of controlled thickness for efficient solid-phase presentation of growth factors. Materials Science and Engineering C: Materials for Biological Applications, 113, 110966. (doi: 10.1016/j.msec.2020.110966) (PMID:32487385)
Greer, A. et al. (2020) Nanopatterned titanium implants accelerate bone formation in vivo. ACS Applied Materials and Interfaces, 12(30), pp. 33541-33549. (doi: 10.1021/acsami.0c10273) (PMID:32633478) (PMCID:PMC7467557)
Cantini, M. , Donnelly, H., Dalby, M. J. and Salmeron-Sanchez, M. (2020) The plot thickens: the emerging role of matrix viscosity in cell mechanotransduction. Advanced Healthcare Materials, 9(8), 1901259. (doi: 10.1002/adhm.201901259) (PMID:31815372)
Huethorst, E. , Cutiongco, M. F.A. , Campbell, F. A., Saeed, A. , Love, R., Reynolds, P. M. , Dalby, M. J. and Gadegaard, N. (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12(2), 025009. (doi: 10.1088/1758-5090/ab5d3f) (PMID:31783378) (PMCID:PMC7655147)
Campsie, P., Childs, P. G., Robertson, S. N., Cameron, K., Hough, J. , Salmeron-Sanchez, M. , Tsimbouri, P. M., Vichare, P., Dalby, M. J. and Reid, S. (2019) Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis. Scientific Reports, 9, 12944. (doi: 10.1038/s41598-019-49422-4) (PMID:31506561) (PMCID:PMC6736847)
Kareem, M. M., Hodgkinson, T., Salmeron-Sanchez, M. , Dalby, M. J. and Tanner, K. E. (2019) Hybrid core-shell scaffolds for bone tissue engineering. Biomedical Materials, 14(2), 025008. (doi: 10.1088/1748-605X/aafbf1) (PMID:30609417)
Sprott, M. R. , Gallego-Ferrer, G., Dalby, M. J. , Salmeron-Sanchez, M. and Cantini, M. (2019) Functionalisation of PLLA with polymer brushes to trigger the assembly of fibronectin into nanonetworks. Advanced Healthcare Materials, 8(3), 1801469. (doi: 10.1002/adhm.201801469) (PMID:30609243)
Cheng, Z. A. et al. (2019) Nanoscale coatings for ultralow dose BMP‐2‐driven regeneration of critical‐sized bone defects. Advanced Science, 6(2), 1800361. (doi: 10.1002/advs.201800361) (PMID:30693176) (PMCID:PMC6343071)
Mas-Moruno, C., Su, B. and Dalby, M. J. (2019) Multifunctional coatings and nanotopographies: towards cell instructive and antibacterial implants. Advanced Healthcare Materials, 8(1), 1801103. (doi: 10.1002/adhm.201801103) (PMID:30468010)
Hay, J. J., Rodrigo-Navarro, A. , Petaroudi, M., Bryksin, A. V., Garcia, A. J., Barker, T. H., Dalby, M. J. and Salmeron-Sanchez, M. (2018) Bacteria-based materials for stem cell engineering. Advanced Materials, 30(43), 1804310. (doi: 10.1002/adma.201804310) (PMID:30209838)
Donnelly, H., Dalby, M. J. , Salmeron-Sanchez, M. and Sweeten, P. E. (2018) Current approaches for modulation of the nanoscale interface in the regulation of cell behavior. Nanomedicine: Nanotechnology, Biology and Medicine, 14(7), pp. 2455-2464. (doi: 10.1016/j.nano.2017.03.020) (PMID:28552647) (PMCID:PMC6173683)
Waddell, S. J., de Andrés, M. C., Tsimbouri, P. M. , Alakpa, E. V., Cusack, M., Dalby, M. J. and Oreffo, R. O.C. (2018) Biomimetic oyster shell-replicated topography alters the behaviour of human skeletal stem cells. Journal of Tissue Engineering, 9, p. 2041731418794007. (doi: 10.1177/2041731418794007) (PMID:30202512) (PMCID:PMC6124183)
Donnelly, H., Salmeron-Sanchez, M. and Dalby, M. J. (2018) Designing stem cell niches for differentiation and self-renewal. Journal of the Royal Society: Interface, 15(145), 20180388. (doi: 10.1098/rsif.2018.0388) (PMID:30158185) (PMCID:PMC6127175)
Robertson, S. N. et al. (2018) Control of cell behaviour through nanovibrational stimulation: nanokicking. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 376(2120), 20170290. (doi: 10.1098/rsta.2017.0290) (PMID:29661978) (PMCID:PMC5915650)
Spadaccio, C., Dalby, M. and Danton, M. H.D. (2018) Daytime variations in perioperative myocardial injury. Lancet, 391(10135), pp. 2105-2106. (doi: 10.1016/S0140-6736(18)30785-2) (PMID:29856342)
Moulisova, V. , Al-Jarsha, M., Leal-Egaña, A., Connell, A., Naudi, K. B., Ayoub, A. F. , Dalby, M. J. and Salmeron-Sanchez, M. (2018) Engineered coatings for titanium implants to present ultralow doses of BMP-7. ACS Biomaterials Science and Engineering, 4(5), pp. 1812-1819. (doi: 10.1021/acsbiomaterials.7b01037) (PMID:29862317) (PMCID:PMC5973637)
Casson, J., O'Kane, S., Smith, C.-A. , Dalby, M. J. and Berry, C. C. (2018) Interleukin 6 plays a role in the migration of magnetically levitated mesenchymal stem cells spheroids. Applied Sciences, 8(3), 412. (doi: 10.3390/app8030412)
Mccully, M., Conde, J., Baptista, P. V., Mullin, M., Dalby, M. J. and Berry, C. C. (2018) Nanoparticle-antagomiR based targeting of miR-31 to induce osterix and osteocalcin expression in mesenchymal stem cells. PLoS ONE, 13(2), e0192562. (doi: 10.1371/journal.pone.0192562) (PMID:29444183) (PMCID:PMC5812622)
Dalby, M. J. , García, A. J. and Salmeron-Sanchez, M. (2018) Receptor control in mesenchymal stem cell engineering. Nature Reviews Materials, 3, 17091. (doi: 10.1038/natrevmats.2017.91)
Allan, C., Ker, A., Smith, C.-A. , Tsimbouri, P. , Borsoi, J., O'Neill, S., Gadegaard, N. , Dalby, M. J. and Meek, D. (2018) Osteoblast response to disordered nanotopography. Journal of Tissue Engineering, 9, pp. 1-7. (doi: 10.1177/2041731418784098) (PMID:30034770) (PMCID:PMC6048666)
Casson, J., Davies, O. G., Smith, C.-A. , Dalby, M. J. and Berry, C. C. (2018) Mesenchymal stem cell-derived extracellular vesicles may promote breast cancer cell dormancy. Journal of Tissue Engineering, 9, p. 2041731418810093. (doi: 10.1177/2041731418810093) (PMID:30627418) (PMCID:PMC6311537)
Damiati, L., Eales, M. G., Nobbs, A. H., Su, B., Tsimbouri, P. , Salmeron-Sanchez, M. and Dalby, M. J. (2018) Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants. Journal of Tissue Engineering, 9, pp. 1-16. (doi: 10.1177/2041731418790694) (PMID:30116518)
Fraioli, R. et al. (2017) Towards the cell-instructive bactericidal substrate: exploring the combination of nanotopographical features and integrin selective synthetic ligands. Scientific Reports, 7, 16363. (doi: 10.1038/s41598-017-16385-3) (PMID:29180787) (PMCID:PMC5703844)
Heydari, T., Heidari, M., Mashinchian, O., Wojcik, M., Xu, K., Dalby, M. J. , Mahmoudi, M. and Ejtehadi, M. R. (2017) Development of a virtual cell model to predict cell response to substrate topography. ACS Nano, 11(9), pp. 9084-9092. (doi: 10.1021/acsnano.7b03732) (PMID:28742318)
Tsimbouri, P. M. et al. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor. Nature Biomedical Engineering, 1, pp. 758-770. (doi: 10.1038/s41551-017-0127-4) (PMID:31015671)
Ballester-Beltrán, J., Trujillo Munoz, S. , Alakpa, E. V., Compañ, V., Gavara, R., Meek, D., West, C. C., Péault, B., Dalby, M. J. and Salmeron-Sanchez, M. (2017) Confined sandwichlike microenvironments tune myogenic differentiation. ACS Biomaterials Science and Engineering, 3(8), pp. 1710-1718. (doi: 10.1021/acsbiomaterials.7b00109) (PMID:28824958) (PMCID:PMC5558191)
Alakpa, E. V., Jayawarna, V., Burgess, K. E.V., West, C. C., Péault, B., Ulijn, R. V. and Dalby, M. J. (2017) Improving cartilage phenotype from differentiated pericytes in tunable peptide hydrogels. Scientific Reports, 7, 6895. (doi: 10.1038/s41598-017-07255-z) (PMID:28761049) (PMCID:PMC5537289)
Alakpa, E. V., Burgess, K. E.V., Chung, P., Riehle, M. O. , Gadegaard, N. , Dalby, M. J. and Cusack, M. (2017) Nacre topography produces higher crystallinity in bone than chemically induced osteogenesis. ACS Nano, 11(7), pp. 6717-6727. (doi: 10.1021/acsnano.7b01044) (PMID:28665112)
Grigoriou, E. , Cantini, M. , Dalby, M.J. , Petersen, A. and Salmeron-Sanchez, M. (2017) Cell migration on material-driven fibronectin microenvironments. Biomaterials Science, 5(7), 1326. (doi: 10.1039/C7BM00333A) (PMID:28612879) (PMCID:PMC5858633)
Wei, D., Sun, J., Bolderson, J., Zhong, M., Dalby, M. J. , Cusack, M. , Yin, H. , Fan, H. and Zhang, X. (2017) Continuous fabrication and assembly of spatial cell-laden fibers for a tissue-like construct via a photolithographic-based microfluidic chip. ACS Applied Materials and Interfaces, 9(17), pp. 14606-14617. (doi: 10.1021/acsami.7b00078) (PMID:28157291)
Moulisová, V. , Gonzalez-Garcia, C., Cantini, M. , Rodrigo-Navarro, A. , Weaver, J., Costell, M., Sabater i Serra, R., Dalby, M. J. , García, A. J. and Salmerón-Sánchez, M. (2017) Engineered microenvironments for synergistic VEGF - integrin signalling during vascularization. Biomaterials, 126, pp. 61-74. (doi: 10.1016/j.biomaterials.2017.02.024) (PMID:28279265) (PMCID:PMC5354119)
Lee, L. et al. (2017) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. Biomaterials, 116, pp. 10-20. (doi: 10.1016/j.biomaterials.2016.11.032) (PMID:27914982) (PMCID:PMC5226065)
Lewis, N. S., Lewis, E. E.L., Mullin, M., Wheadon, H. , Dalby, M. J. and Berry, C. C. (2017) Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence. Journal of Tissue Engineering, 8, pp. 1-11. (doi: 10.1177/2041731417704428) (PMID:28616152) (PMCID:PMC5460809)
Donnelly, H., Smith, C.-A. , Sweeten, P. E., Gadegaard, N. , Meek, D., D'Este, M., Mata, A., Eglin, D. and Dalby, M. J. (2017) Bone and cartilage differentiation of a single stem cell population driven by material interface. Journal of Tissue Engineering, 8, pp. 1-10. (doi: 10.1177/2041731417705615) (PMID:28567273) (PMCID:PMC5438107)
Tsimbouri, P.M. , Fisher, L., Holloway, N., Sjostrom, T., Meek, R.M.D., Su, B. and Dalby, M.J. (2016) Osteogenic and bactericidal surfaces from hydrothermal titania nanowires on titanium substrates. Scientific Reports, 6, 36857. (doi: 10.1038/srep36857) (PMID:27857168) (PMCID:PMC5114696)
Lewis, E. E. L., Wheadon, H. , Lewis, N., Yang, J., Mullin, M., Hursthouse, A., Stirling, D., Dalby, M. J. and Berry, C. C. (2016) A quiescent, regeneration-responsive tissue engineered mesenchymal stem cell bone marrow niche model via magnetic levitation. ACS Nano, 10(9), pp. 8346-8354. (doi: 10.1021/acsnano.6b02841) (PMID:27602872)
Rico, P., Mnatsakanyan, H., Dalby, M. J. and Salmeron-Sanchez, M. (2016) Material-driven fibronectin assembly promotes maintenance of mesenchymal stem cell phenotypes. Advanced Functional Materials, 26(36), pp. 6563-6573. (doi: 10.1002/adfm.201602333)
Laing, S., Suriano, R., Lamprou, D. A., Smith, C.-A. , Dalby, M. J. , Mabbott, S., Faulds, K. and Graham, D. (2016) Thermoresponsive polymer micropatterns fabricated by dip-pen nanolithography for a Highly controllable substrate with potential cellular applications. ACS Applied Materials and Interfaces, 8(37), pp. 24844-24852. (doi: 10.1021/acsami.6b03860) (PMID:27572916)
Aguayo, S., Strange, A., Gadegaard, N. , Dalby, M.J. and Bozec, L. (2016) Influence of biomaterial nanotopography on the adhesive and elastic properties of Staphylococcus aureus cells. RSC Advances, 6(92), pp. 89347-89355. (doi: 10.1039/C6RA12504B)
Alakpa, E. et al. (2016) Tunable supramolecular hydrogels for selection of lineage guiding metabolites in stem cell cultures. Chem, 1(2), pp. 298-319. (doi: 10.1016/j.chempr.2016.07.001)
Llopis-Hernández, V. , Cantini, M. , González-García, C., Cheng, Z. A., Yang, J., Tsimbouri, P. M. , García, A. J., Dalby, M. J. and Salmerón-Sánchez, M. (2016) Material-driven fibronectin assembly for high-efficiency presentation of growth factors. Science Advances, 2(8), e1600188. (doi: 10.1126/sciadv.1600188) (PMID:27574702) (PMCID:PMC5001810)
Ngandu Mpoyi, E., Cantini, M. , Reynolds, P. M. , Gadegaard, N. , Dalby, M. J. and Salmerón-Sánchez, M. (2016) Protein adsorption as a key mediator in the nanotopographical control of cell behavior. ACS Nano, 10(7), pp. 6638-6647. (doi: 10.1021/acsnano.6b01649) (PMID:27391047) (PMCID:PMC4980054)
Roberts, J. N. et al. (2016) Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation. ACS Nano, 10(7), pp. 6667-6679. (doi: 10.1021/acsnano.6b01765) (PMID:27322014) (PMCID:PMC4963921)
Nikukar, H., Childs, P. G., Curtis, A. S., Martin, I. W. , Riehle, M. O. , Dalby, M. J. and Reid, S. (2016) Production of nanoscale vibration for stimulation of human mesenchymal stem cells. Journal of Biomedical Nanotechnology, 12(7), pp. 1478-1488. (doi: 10.1166/jbn.2016.2264)
Silverwood, R. K. et al. (2016) Analysis of osteoclastogenesis/osteoblastogenesis on nanotopographical titania surfaces. Advanced Healthcare Materials, 5(8), pp. 947-955. (doi: 10.1002/adhm.201500664) (PMID:26890261)
Childs, P. G., Boyle, C., Pemberton, G. D., Nikukar, H., Curtis, A. S.G., Henriquez, F. L., Dalby, M. J. and Reid, S. (2016) Use of nanoscale mechanical stimulation for control and manipulation of cell behaviour. Acta Biomaterialia, 34, pp. 159-168. (doi: 10.1016/j.actbio.2015.11.045) (PMID:6612418))
Anderson, H. J., Dalby, M. J. , Sahoo, J. and Uljin, R. (2016) Mesenchymal stem cell fate: applying biomaterials for control of stem cell behaviour. Frontiers in Bioengineering and Biotechnology, 4, 38. (doi: 10.3389/fbioe.2016.00038) (PMID:27242999) (PMCID:PMC4865671)
Stipetic, L. H., Dalby, M. J. , Davies, R. L. , Morton, F. r. , Ramage, G. and Burgess, K. (2016) A novel metabolomic approach used for the comparison of Staphylococcus aureus planktonic cells and biofilm samples. Metabolomics, 12, 75. (doi: 10.1007/s11306-016-1002-0) (PMID:27013931) (PMCID:PMC4783440)
Hay, J., Rodrigo-Navarro, A. , Hassi, K., Moulisova, V. , Dalby, M. J. and Salmeron-Sanchez, M. (2016) Living biointerfaces based on non-pathogenic bacteria support stem cell differentiation. Scientific Reports, 6, 21809. (doi: 10.1038/srep21809) (PMID:26902619) (PMCID:PMC4763179)
Bathawab, F., Bennett, M., Cantini, M. , Reboud, J. , Dalby, M. and Salmeron-Sanchez, M. (2016) Lateral chain length in polyalkyl acrylates determines the mobility of fibronectin at the cell/material interface. Langmuir, 32(3), pp. 800-809. (doi: 10.1021/acs.langmuir.5b03259) (PMID:26715432) (PMCID:PMC4732669)
Alfotawi, R., Ayoub, A. , Tanner, K. E. , Dalby, M. , Busuttil Naudi, K. and McMahon, J. (2016) A novel surgical approach for the reconstruction of critical-size mandibular defects using calcium sulphate/hydroxyapatite cement, BMP-7 and mesenchymal stem cells-histological assessment. Journal of Biomaterials and Tissue Engineering, 6(1), pp. 1-11. (doi: 10.1166/jbt.2016.1412)
Davison, M. J., McMurray, R. J., Smith, C.-A. , Dalby, M. and Meek, R.M. D. (2016) Nanopit-induced osteoprogenitor cell differentiation: the effect of nanopit death. Journal of Tissue Engineering, 7, pp. 1-8. (doi: 10.1177/2041731416652778) (PMID:27298716)
Salmeron-Sanchez, M. and Dalby, M. J. (2016) Synergistic growth factor microenvironments. Chemical Communications, 52(91), pp. 13327-13336. (doi: 10.1039/C6CC06888J) (PMID:27722261)
Haggarty, J., Oppermann, M., Dalby, M. J. , Burchmore, R. J. , Cook, K., Weidt, S. and Burgess, K. E.V. (2015) Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome. Metabolomics, 11(5), pp. 1465-1470. (doi: 10.1007/s11306-014-0770-7) (PMID:26366140) (PMCID:PMC4559102)
Estévez, M., Martínez, E., Yarwood, S. J., Dalby, M. J. and Samitier, J. (2015) Adhesion and migration of cells responding to microtopography. Journal of Biomedical Materials Research Part A, 103(5), pp. 1659-1668. (doi: 10.1002/jbm.a.35293) (PMID:25089034)
Stipetic, L. H., Hamilton, G., Dalby, M. J. , Davies, R. L. , Meek, R.M. D., Ramage, G. , Smith, D. G.E. and Burgess, K. E.V. (2015) Draft genome sequence of isolate staphylococcus aureus LHSKBclinical, isolated from an infected hip. Genome Announcements, 3(2), e00336-15. (doi: 10.1128/genomeA.00336-15) (PMID:25931597) (PMCID:PMC4417693)
Ballester-Beltrán, J., Biggs, M., Dalby, M. , Salmeron-Sanchez, M. and Leal-Egana, A. (2015) Sensing the difference: the influence of anisotropic cues on cell behavior. Frontiers in Materials, 2, 39. (doi: 10.3389/fmats.2015.00039)
Chong, D.S.T., Turner, L.-A., Gadegaard, N. , Seifalian, A.M., Dalby, M.J. and Hamilton, G. (2015) Nanotopography and plasma treatment: redesigning the surface for vascular graft endothelialisation. European Journal of Vascular and Endovascular Surgery, 49(3), pp. 335-343. (doi: 10.1016/j.ejvs.2014.12.008) (PMID:25579872)
Johnstone, S. A., Liley, M., Dalby, M. J. and Barnett, S. C. (2015) Comparison of human olfactory and skeletal MSCs using osteogenic nanotopography to demonstrate bone-specific bioactivity of the surfaces. Acta Biomaterialia, 13, pp. 266-276. (doi: 10.1016/j.actbio.2014.11.027) (PMID:25463488)
Dalby, M. J. and Biggs, M. J.P. (2015) Special focus on nanoscale regeneration. Nanomedicine, 10(5), pp. 677-680. (doi: 10.2217/nnm.15.34)
Mashinchian, O., Turner, L.-A., Dalby, M. J. , Laurent, S., Shokrgozar, M. A., Bonakdar, S., Imani, M. and Mahmoudi, M. (2015) Regulation of stem cell fate by nanomaterial substrates. Nanomedicine, 10(5), pp. 829-847. (doi: 10.2217/nnm.14.225) (PMID:25816883)
Pemberton, G. D., Childs, P., Reid, S., Nikukar, H., Tsimbouri, M. , Gadegaard, N. , Curtis, A. S. and Dalby, M. J. (2015) Nanoscale stimulation of osteoblastogenesis from mesenchymal stem cells: nanotopography and nanokicking. Nanomedicine, 10(4), pp. 547-560. (doi: 10.2217/nnm.14.134) (PMID:25723089)
Young, P.S., Tsimbouri, P.M. , Gadegaard, N. , Meek, R.M.D. and Dalby, M.J. (2015) Osteoclastogenesis/osteoblastogenesis using human bone marrow-derived cocultures on nanotopographical polymer surfaces. Nanomedicine, 10(6), pp. 949-957. (doi: 10.2217/nnm.14.146) (PMID:25867859)
Halai, M., Ker, A., Meek, R.M. D., Nadeem, D., Sjostrom, T., Su, B., McNamara, L. E., Dalby, M. J. and Young, P. S. (2014) Scanning electron microscopical observation of an osteoblast/osteoclast co-culture on micropatterned orthopaedic ceramics. Journal of Tissue Engineering, 5, (doi: 10.1177/2041731414552114) (PMID:25383174) (PMCID:PMC4221946)
McNamara, L. E., Sjostrom, T., Seunarine, K., Meek, R.M. D., Su, B. and Dalby, M. J. (2014) Investigation of the limits of nanoscale filopodial interactions. Journal of Tissue Engineering, 5, p. 2041731414536177. (doi: 10.1177/2041731414536177) (PMID:24904726) (PMCID:PMC4046805)
Wang, J. R., Ahmed, S. F. , Gadegaard, N. , Meek, R.M. D., Dalby, M. J. and Yarwood, S. J. (2014) Nanotopology potentiates growth hormone signalling and osteogenesis of mesenchymal stem cells. Growth Hormone and IGF Research, 24(6), pp. 245-250. (doi: 10.1016/j.ghir.2014.10.003) (PMID:25466909)
Yang, J., McNamara, L. E., Gadegaard, N. , Alakpa, E. V., Burgess, K. V., Meek, D. and Dalby, M. J. (2014) Nanotopographical induction of osteogenesis through adhesion, bone morphogenic protein co-signaling and regulation of microRNAs. ACS Nano, 8(10), pp. 9941-9953. (doi: 10.1021/nn504767g) (PMID:25227207)
Alfotawi, R., Ayoub, A. F. , Heath, N., Naudi, K. B., Tanner, K. E. , Dalby, M. J. and McMahon, J. (2014) Radiological assessment of bioengineered bone in a muscle flap for the reconstruction of critical-size mandibular defect. PLoS ONE, 9(9), e107403. (doi: 10.1371/journal.pone.0107403) (PMID:25226170) (PMCID:PMC4167331)
McMurray, R. J., Dalby, M. and Tsimbouri, P. M. (2014) Using biomaterials to study stem cell mechanotransduction, growth and differentiation. Journal of Tissue Engineering and Regenerative Medicine, 9(5), pp. 528-539. (doi: 10.1002/term.1957) (PMID:25370612)
Cassidy, J.W., Roberts, J.N. , Smith, C.-A. , Robertson, M., White, K., Biggs, M.J., Oreffo, R.O.C. and Dalby, M.J. (2014) Osteogenic lineage restriction by osteoprogenitors cultured on nanometric grooved surfaces – the role of focal adhesion maturation. Acta Biomaterialia, 10(2), pp. 651-660. (doi: 10.1016/j.actbio.2013.11.008) (PMID:24252447) (PMCID:PMC3907683)
Tsimbouri, P. , Gadegaard, N., Burgess, K., White, K., Reynolds, P. , Herzyk, P. , Oreffo, R. and Dalby, M.J. (2014) Nanotopographical effects on mesenchymal stem cell morphology and phenotype. Journal of Cellular Biochemistry, 115(2), pp. 380-390. (doi: 10.1002/jcb.24673) (PMID:24123223)
Dalby, M. J. , Gadegaard, N. and Oreffo, R. O.C. (2014) Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate. Nature Materials, 13(6), pp. 558-569. (doi: 10.1038/NMAT3980)
Mashinchian, O. et al. (2014) Cell-imprinted substrates act as an artificial niche for skin regeneration. ACS Applied Materials and Interfaces, 6(15), pp. 13280-13292. (doi: 10.1021/am503045b) (PMID:24967724)
McNamara, L. E., Dalby, M. J. and Tsimbouri, M. P. (2014) The use of microarrays and fluorescence in situ hybridization for the study of mechanotransduction from topography. Methods in Cell Biology, 119, pp. 293-309. (doi: 10.1016/B978-0-12-416742-1.00015-9) (PMID:24439291)
Turner, L.-A. and Dalby, M. (2014) Nanotopography – potential relevance in the stem cell niche. Biomaterials Science, 2(11), pp. 1574-1594. (doi: 10.1039/c4bm00155a)
Dalby, M.J. , Lee, L.C., Yang, J., MacIntyre, A. and McCully, M. (2013) Hydrogel nanoparticles for drug delivery. Nanomedicine, 8(11), pp. 1744-1745.
Dalby, M.J. , Lee, L.C., Yang, J., MacIntyre, A. and McCully, M. (2013) Periodicity is important in stem cell response. Nanomedicine, 8(11), p. 1744.
Alfotawi, R., Busuttil Naudi, K., Dalby, M. , Tanner, K.E. , McMahon, J. and Ayoub, A. (2013) Assessment of cellular viability on calcium sulphate/hydroxyapatite injectable scaffolds. Journal of Tissue Engineering, 4, p. 204173. (doi: 10.1177/2041731413509645)
Seras-Franzoso, J., Peebo, K., Corchero, J.L., Tsimbouri, P.M. , Unzueta, U., Rinas, U., Dalby, M.J. , Vazquez, E., García-Fruitós, E. and Villaverde, A. (2013) A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs. Nanomedicine, 8(10), pp. 1587-1599. (doi: 10.2217/nnm.12.188)
Curtis, A. S.G., Reid, S., Martin, I. , Vaidyanathan, R., Smith, C.-A. , Nikukar, H. and Dalby, M. J. (2013) Cell interactions at the nanoscale: piezoelectric stimulation. IEEE Transactions on NanoBioscience, 12(3), pp. 247-254. (doi: 10.1109/TNB.2013.2257837) (PMID:23771395)
Kingham, E., White, K., Gadegaard, N. , Dalby, M.J. and Oreffo, R.O.C. (2013) Nanotopographical cues augment mesenchymal differentiation of human embryonic stem cells. Small, 9(12), pp. 2140-2151. (doi: 10.1002/smll.201202340)
Nikukar, H., Reid, S.W.J., Tsimbouri, P.M. , Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2013) Osteogenesis of mesenchymal stem cells by nanoscale mechanotransduction. ACS Nano, 7(3), pp. 2758-2767. (doi: 10.1021/nn400202j)
Wiejak, J., Tsimbouri, P. M. , Herzyk, P. , Dalby, M. J. , Hamilton, G. and Yarwood, S. J. (2013) Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves. Biomaterials, 34(8), pp. 1967-1979. (doi: 10.1016/j.biomaterials.2012.11.036) (PMID:23245923) (PMCID:PMC3543902)
Maclaine, S.E., McNamara, L.E., Bennett, A.J., Dalby, M.J. and Meek, R.M. (2013) Developments in stem cells: implications for future joint replacements. Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine, 227(3), pp. 275-283. (doi: 10.1177/0954411912471492)
Tsimbouri, P. M. , Murawski, K., Hamilton, G., Herzyk, P. , Oreffo, R. O.C., Gadegaard, N. and Dalby, M. J. (2013) A genomics approach in determining nanotopographical effects on MSC phenotype. Biomaterials, 34(9), pp. 2177-2184. (doi: 10.1016/j.biomaterials.2012.12.019) (PMID:23312853) (PMCID:PMC3573234)
Reynolds, P.M. , Pedersen, R.H., Stormonth-Darling, J., Dalby, M.J. , Riehle, M.O. and Gadegaard, N. (2013) Label-free segmentation of co-cultured cells on a nanotopographical gradient. Nano Letters, 13(2), pp. 570-576. (doi: 10.1021/nl304097p)
Sjöström, T., Brydone, A.S., Meek, R.M.D., Dalby, M.J. , Su, B. and McNamara, L.E. (2013) Titanium nanofeaturing for enhanced bioactivity of implanted orthopedic and dental devices. Nanomedicine, 8(1), pp. 89-104. (doi: 10.2217/NNM.12.177)
Seras-Franzoso, J., Tsimbouri, P.M. , Burgess, K.V., Unzueta, U., Garcia-Fruitos, E., Vazquez, E., Villaverde, A. and Dalby, M.J. (2013) Topographically targeted osteogenesis of mesenchymal stem cells stimulated by inclusion bodies attached to polycaprolactone surfaces. Nanomedicine, 9(2), pp. 207-220. (doi: 10.2217/nnm.13.43) (PMID:23631503)
Tsimbouri, P.M. , McMurray, R.J., Burgess, K.V., Alakpa, E.V., Reynolds, P. , Murawski, K., Kingham, E., Oreffo, R.O.C., Gadegaard, N. and Dalby, M.J. (2012) Using nanotopography and metabolomics to identify biochemical effectors of multipotency. ACS Nano, 6(11), pp. 10239-10249. (doi: 10.1021/nn304046m)
McNamara, L.E., Burchmore, R.J.S. , Riehle, M.O. , Herzyk, P. , Biggs, M.J.P., Wilkinson, C.D.W., Curtis, A.S.G. and Dalby, M.J. (2012) The role of microtopography in cellular mechanotransduction. Biomaterials, 33(10), pp. 2835-2847. (doi: 10.1016/j.biomaterials.2011.11.047)
Dalby, M.J. , Macintyre, A., Roberts, J.N. , Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Nanosubstrates to illustrate differential adhesion mechanisms to fibronectin and vitronectin. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Alakpa, E., Jayarwarna, V., Burgess, K. and Dalby, M. (2012) Characterisation of peptide biomaterials & innate metabolites that direct stem cell differentiation in vitro. European Cell and Materials, 23(Sup 4), p. 50.
Alberdi, M.P., Dalby, M.J. , Rodriguez-Andres, J., Fazakerley, J.K., Kohl, A. and Bell-Sakyi, L. (2012) Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines. Ticks and Tick-borne Diseases, 3(3), pp. 137-146. (doi: 10.1016/j.ttbdis.2012.05.002)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L..L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) 3D patterned agarose hydrogels for investigation of precursor cells in differentiation and chemoattraction. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Nanoporous titanium substrates for osteogenesis. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Dalby, M.J. , Macintyre, A., Roberts, J.N., Yang, J., Lee, L.C.Y., Tsimbouri, P.M. and McNamara, L.E. (2012) Research Highlights. Nanomedicine, 7(1), pp. 17-21. (doi: 10.2217/nnm.11.172)
Kuboki, T., Kantawong, F., Burchmore, R. , Dalby, M.J. and Kidoaki, S. (2012) 2D-DIGE proteomic analysis of mesenchymal stem cell cultured on the elasticity-tunable hydrogels. Cell Structure and Function, 37(2), pp. 127-139. (doi: 10.1247/csf.12012)
Maclaine, S.E., Gadhari, N., Pugin, R., Meek, R.M.D., Liley, M. and Dalby, M.J. (2012) Optimizing the osteogenicity of nanotopography using block co-polymer phase separation fabrication techniques. Journal of Orthopaedic Research, 30(8), pp. 1190-1197. (doi: 10.1002/jor.22076)
McNamara, L.E., Kantawong, F., Dalby, M.J. , Riehle, M.O. and Burchmore, R.J.S. (2012) Preventing and troubleshooting artefacts in saturation labelled fluorescence 2D difference gel electrophoresis (saturation DiGE). Proteomics, 11(24), pp. 4610-4621. (doi: 10.1002/pmic.201100135)
McNamara, L. E. et al. (2011) Skeletal stem cell physiology on functionally distinct titania nanotopographies. Biomaterials, 32(30), pp. 7403-7410. (doi: 10.1016/j.biomaterials.2011.06.063)
McMurray, R.J., Gadegaard, N. , Tsimbouri, P.M. , Burgess, K.V., McNamara, L.E., Tare, R., Murawski, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. Nature Materials, 10(8), pp. 637-644. (doi: 10.1038/nmat3058) (PMID:21765399)
Kantawong, F., Robertson, M.E., Gadegaard, N. , Oreffo, R.O.C., Burchmore, R.J. and Dalby, M.J. (2011) Protein expression of STRO-1 cells in response to different topographic features. Journal of Tissue Engineering, 2011, 534603. (doi: 10.4061/2011/534603) (PMID:21772957) (PMCID:PMC3136090)
Wilkinson, A., Hewitt, R. N., McNamara, L. E., McCloy, D., Meek, R.M. D. and Dalby, M. J. (2011) Biomimetic microtopography to enhance osteogenesis in vitro. Acta Biomaterialia, 7(7), pp. 2919-2925. (doi: 10.1016/j.actbio.2011.03.026)
Brydone, A. S., Dalby, M. J. , Berry, C. C. , Dominic Meek, R.M. D. and McNamara, L. E. (2011) Grooved surface topography alters matrix-metalloproteinase production by human fibroblasts. Biomedical Materials, 6(3), 035005. (doi: 10.1088/1748-6041/6/3/035005) (PMID:21505230)
Kingham, E.J., Tsimbouri, P.M. , Gadegaard, N. , Dalby, M.J. and Oreffo, R.O.C. (2011) Nanotopography induced osteogenic differentiation of human stem cells. Bone, 48(Sup. 2), S108-S109. (doi: 10.1016/j.bone.2011.03.177)
Alakpa, E., Jayawarna, V., Burgess, K. and Dalby, M. (2011) Elucidating cellular reaction to biomaterial substrates using a metabolomics approach. European Cells and Materials, 22(Sup 3), p. 18.
Biggs, M. J.P., Richards, R. G. and Dalby, M. J. (2011) Using immuno-scanning electron microscopy for the observation of focal adhesion-substratum interactions at the nano- and microscale in S-phase cells. Methods in Molecular Biology, 695, pp. 53-60. (doi: 10.1007/978-1-60761-984-0_4)
McNamara, L.E., McMurray, R.J., Dalby, M.J. and Tsimbouri, P.M. (2011) Surfaces and Cell Behavior. Comprehensive Biomaterials, 4(409), pp. 115-126. (doi: 10.1016/B978-0-08-055294-1.00010-6)
Tsimbouri, P. , Gadegaard, N. , Burgess, K., Kingham, E., Oreffo, R.O.C. and Dalby, M.J. (2011) Mechanotransduction and skeletal stem cell differentiation in response to bioactive nanotopography. Histology and Histopathology: Cellular and Molecular Biology, 26(S1), 31.012.
Tsimbouri, P. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2011) Effects of nanotopography on cell adhesion, morphology and differentiation. European Cells and Materials, 22(S2), p. 14.
Tanner, K.E. and Dalby, M.J. (2010) Guest editorial: special issue on bone tissue engineering. Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine, 224(12), i-iv. (doi: 10.1177/095441191022401201)
Biggs, M.J.P., Richards, R.G. and Dalby, M.J. (2010) Nanotopographical modification: a regulator of cellular function through focal adhesions. Nanomedicine: Nanotechnology, Biology and Medicine, 6(5), pp. 619-633. (doi: 10.1016/j.nano.2010.01.009)
Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Riehle, M.O. , Oreffo, R.O., Dalby, M.J. and Burchmore, R. (2010) Effects of a surface topography composite with puerariae radix on human STRO-1-positive stem cells. Acta Biomaterialia, 6(9), pp. 3694-3703. (doi: 10.1016/j.actbio.2010.02.038)
McNamara, L.E., Dalby, M.J., Riehle, M.O. and Burchmore, R.J.S. (2010) Fluorescence two-dimensional difference gel electrophoresis for biomaterial applications. Journal of the Royal Society: Interface, 7(Sppl 1), S107-S118. (doi: 10.1098/rsif.2009.0177.focus)
Biggs, M.J.P. and Dalby, M.J. (2010) Focal adhesions in osteoneogenesis. Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine, 224(12), pp. 1441-1453. (doi: 10.1243/09544119JEIM775)
Chrzanowski, W., Abou Neel, E.A., Lee, K.Y., Bismarck, A., Young, A.M., Hart, A.D., Dalby, M.J. and Knowles, J.C. (2010) Tailoring Cell Behavior on Polymers by the Incorporation of Titanium Doped Phosphate Glass Filler. Advanced Biomaterials, 12(7), B298-B308. (doi: 10.1002/adem.200980083)
McMurray, R.J., Gadegaard, N. , Dalby, M.J. , Tsimbouri, P.M. , Maclaine, S., Meek, D., McNamara, L.E., Child, H. and Berry, C.C. (2010) Research highlights. Nanomedicine, 5(10), pp. 1495-1499. (doi: 10.2217/nnm.10.119)
McNamara, L.E., McMurray, R.J., Biggs, M.J.P., Kantawong, F., Oreffo, R.O.C. and Dalby, M.J. (2010) Nanotopographical Control of Stem Cell Differentiation. Journal of Tissue Engineering, 2010(Art 12), pp. 1-13. (doi: 10.4061/2010/120623)
McPhee, G., Dalby, M.J. , Riehle, M.O. and Yin, H. (2010) Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study. Medical and Biological Engineering and Computing, 48(10), (doi: 10.1007/s11517-010-0657-3)
Kantawong, F., Burchmore, R.J.S. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Proteomic analysis of human osteoprogenitor response to disordered nanotopography. Journal of the Royal Society: Interface, (doi: 10.1098/rsif.2008.0447)
Biggs, M.J.P., Richards, R.G., Gadegaard, N. , McMurray, R.J., Affrosman, S., Wilkinson, C.D., Oreffo, R.O.C. and Dalby, M.J. (2009) Interactions with nanoscale topography: adhesion quantification and signal transduction in cells of osteogenic and multipotent lineage. Journal of Biomedical Materials Research Part A, 91A(1), pp. 195-208. (doi: 10.1002/jbm.a.32196)
Biggs, M.J.P., Richards, R.G., Gadegaard, N. , Wilkinson, C.D.W., Oreffo, R.O.C. and Dalby, M.J. (2009) The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells. Biomaterials, 30(28), pp. 5094-5103. (doi: 10.1016/j.biomaterials.2009.05.049)
Kantawong, F., Burgess, K.E.V., Jayawardena, K., Hart, A., Burchmore, R.J. , Gadegaard, N. , Oreffo, R.O.C. and Dalby, M.J. (2009) Whole proteome analysis of osteoprogenitor differentiation induced by disordered nanotopography and mediated by ERK signalling. Biomaterials, 30(27), pp. 4723-4731. (doi: 10.1016/j.biomaterials.2009.05.040)
Rossi, L., Riehle, M.O. , McNamara, L.E., Burchmore, R. , Dalby, M.J. , McMurray, R.J., Gadegaard, N. , Ahmed, S. and Tsimbouri, P.M. (2009) Research highlights. Nanomedicine, 4(6), pp. 613-617. (doi: 10.2217/nnm.09.46)
Kantawong, F., Burchmore, R.J.S., Wilkinson, C.D.W., Oreffo, R.O.C. and Dalby, M.J. (2009) Differential in-gel electrophoresis (DIGE) analysis of human bone marrow osteoprogenitor cell contact guidance. Acta Biomaterialia, 5(4), pp. 1137-1146. (doi: 10.1016/j.actbio.2008.11.001)
Dalby, M.J. (2009) Nanostructured surfaces: cell engineering and cell biology. Nanomedicine, 4(3), pp. 247-248. (doi: 10.2217/nnm.09.1)
Sjostrom, T., Dalby, M.J. , Hart, A., Tare, R., Oreffo, R.O.C. and Su, B. (2009) Fabrication of pillar-like titania nanostructures on titanium and their interactions with human skeletal stem cells. Acta Biomaterialia, 5(5), pp. 1433-1441. (doi: 10.1016/j.actbio.2009.01.007)
Dalby, M.J. , McNamara, L.E., Riehle, M.O. , Burchmore, R.J.S. , Kuntanawat, P., McMurray, R.J., Gadegaard, N. and Andar, A. (2008) Research highlights. Nanomedicine, 3(4), pp. 411-414. (doi: 10.2217/17435889.3.4.411)
Dalby, M.J., Hart, A. and Yarwood, S.J. (2008) The effect of the RACK1 signalling protein on the regulation of cell adhesion and cell contact guidance on nanometric grooves. Biomaterials, 29(3), pp. 282-289. (doi: 10.1016/j.biomaterials.2007.09.030)
Biggs, M.J., Richards, R.G., Wilkinson, C.D. and Dalby, M.J. (2008) Focal adhesion interactions with topographical structures: a novel method for immuno-SEM labelling of focal adhesions in S-phase cells. Journal of Microscopy, 231(1), pp. 28-37. (doi: 10.1111/j.1365-2818.2008.02013.x)
Biggs, M.J.P., Richards, R.G., McFarlane, S., Wilkinson, C.D.W., Oreffo, R.O.C. and Dalby, M.J. (2008) Adhesion formation of primary human osteoblasts and the functional response of mesenchymal stem cells to 330nm deep microgrooves. Journal of the Royal Society: Interface, (doi: 10.1098/rsif.2008.0035)
Dalby, M.J. , Andar, A., Nag, A., Affrosman, S., Tare, R., McFarlane, S. and Oreffo, R.O.C. (2008) Genomic expression of mesenchymal stem cells to altered nanoscale topographies. Journal of the Royal Society: Interface, 5(26), pp. 1055-1065. (doi: 10.1098/rsif.2008.0016)
Dalby, M.J. , Gadegaard, N. and Wilkinson, C.D.W. (2008) The response of fibroblasts to hexagonal nanotopography fabricated by electron beam lithography. Journal of Biomedical Materials Research Part A, 84A(4), pp. 973-979. (doi: 10.1002/jbm.a.31409)
Gadegaard, N. , Dalby, M.J. , Riehle, M.O. and Wilkinson, C.D.W. (2008) Optimizing substrate disorder for bone tissue engineering of mesenchymal stem cells. Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures, 26(6), pp. 2554-2557. (doi: 10.1116/1.2978407)
Kantawong, F., Dalby, M. and Burchmore, R. (2007) Differential proteomics evaluation of osteoprogenitor growth on microgrooved surfaces using bioreactor culture. Comparative Biochemistry and Physiology. Part A: Molecular and Integrative Physiology, 146(4), S192. (doi: 10.1016/j.cbpa.2007.01.420)
Biggs, M.J.P., Richards, R.G., Gadegaard, N. , Wilkinson, C.D.W. and Dalby, M.J. (2007) The effects of nanoscale pits on primary human osteoblast adhesion formation and cellular spreading. Journal of Materials Science: Materials in Medicine, 18, pp. 399-404. (doi: 10.1007/s10856-006-0705-6)
Biggs, M.J.P., Richards, R.G., Gadegaard, N. , Wilkinson, C.D.W. and Dalby, M.J. (2007) Regulation of implant surface cell adhesion: Characterization and quantification of S-phase primary osteoblast adhesions on biomimetic nanoscale substrates. Journal of Orthopaedic Research, 25, pp. 273-282. (doi: 10.1002/jor.20319)
Dalby, M.J. (2007) The beta integrins and cytoskeletal nanoimprinting. Experimental Cell Research, 314(4), pp. 927-935. (doi: 10.1016/j.yexcr.2007.10.003)
Dalby, M.J. (2007) Cellular response to low adhesion nanotopographies. International Journal of Nanomedicine, 2(3), pp. 373-381.
Dalby, M.J. (2007) Nanotopographical control of human osteoprogenitor differentiation. Current Stem Cell Research and Therapy, 2(2), pp. 129-138.
Dalby, M.J. , Biggs, M.J.P., Gadegaard, N. , Kalna, G., Wilkinson, C.D.W. and Curtis, A.S.G. (2007) Nanotopographical stimulation of mechanotransduction and changes in interphase centromere positioning. Journal of Cellular Biochemistry, 100, pp. 326-338. (doi: 10.1002/jcb.21058)
Dalby, M.J. , Gadegaard, N. , Herzyk, P. , Agheli, H., Sutherland, D.S. and Wilkinson, C.D.W. (2007) Group analysis of regulation of fibroblast genome on low-adhesion nanostructures. Biomaterials, 28, pp. 1761-1769. (doi: 10.1016/j.biomaterials.2006.11.049)
Dalby, M.J. , Gadegaard, N. , Tare, R., Andar, A., Riehle, M.O. , Herzyk, P. , Wilkinson, C.D.W. and Oreffo, R.O.C. (2007) The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nature Materials, 6(12), pp. 997-1003. (doi: 10.1038/nmat2013)
Hart, A., Gadegaard, N., Wilkinson, C., Oreffo, R. and Dalby, M. (2007) Osteoprogenitor response to low-adhesion nanotopographies originally fabricated by electron beam lithography. Journal of Materials Science: Materials in Medicine, 18, pp. 1211-1218. (doi: 10.1007/s10856-007-0157-7)
Berry, C.C. , Dalby, M.J., Oreffo, R.O.C., McCloy, D. and Affrosman, S. (2006) The interaction of human bone marrow cells with nanotopographical features in three dimensional constructs. Journal of Biomedical Materials Research Part A, 79A, pp. 431-439. (doi: 10.1002/jbm.a.30960)
Curtis, A.S.G., Dalby, M.J. and Gadegaard, N. (2006) Cell signaling arising from nanotopography: implications for nanomedical devices. Nanomedicine, 1, pp. 67-72. (doi: 10.2217/17435889.1.1.67)
Curtis, A., Dalby, M. and Gadegaard, N. (2006) Nanoprinting onto cells. Journal of the Royal Society: Interface, 3, pp. 393-398. (doi: 10.1098/rsif.2005.0104)
Dalby, M.J. , McCloy, D., Robertson, M., Agheli, H., Sutherland, D., Affrossman, S. and Oreffo, R.O.C. (2006) Osteoprogenitor response to semi-ordered and random nanotopographies. Biomaterials, 27(15), pp. 2980-2987. (doi: 10.1016/j.biomaterials.2006.01.010)
Dalby, M., McCloy, D., Robertson, M., Wilkinson, C. and Oreffo, R. (2006) Osteoprogenitor response to defined topographies with nanoscale depths. Biomaterials, 27, pp. 1306-1315. (doi: 10.1016/j.biomaterials.2005.08.028)
Berry, C., Dalby, M., McCloy, D. and Affrossman, S. (2005) The fibroblast response to tubes exhibiting internal nanotopography. Biomaterials, 26, pp. 4985-4992. (doi: 10.1016/j.biomaterials.2005.01.046)
Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2005) Morphological and microarray analysis of human fibroblasts cultured on nanocolumns produced by colloidal lithography. European Cells and Materials, 9, pp. 1-8.
Dalby, M. (2005) Topographically induced direct cell mechanotransduction. Medical Engineering and Physics, 27, pp. 730-742. (doi: 10.1016/j.medengphy.2005.04.005)
Gadegaard, N. , Dalby, M.J. , Riehle, M.O. , Curtis, A.S.G. and Affrossman, S. (2004) Tubes with controllable internal nanotopography. Advanced Materials, 20, pp. 1857-1860. (doi: 10.1002/adma.200400408)
Dalby, M.J. , Gadegaard, N. , Riehle, M.O. , Wilkinson, C.D.W. and Curtis, A.S.G. (2004) Investigating filopodia sensing using arrays of defined nano-pits down to 35 nm diameter in size. International Journal of Biochemistry and Cell Biology, 36(10), pp. 2005-2015. (doi: 10.1016/j.biocel.2004.03.001)
Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Changes in fibroblast morphology in response to nano-columns produced by colloidal lithography. Biomaterials, 25(23), pp. 5415-5422. (doi: 10.1016/j.biomaterials.2003.12.049) (PMID:15130726)
Dalby, M.J. , Berry, C.C. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Attempted endocytosis of nano-environment produced by colloidal lithography by human fibroblasts. Experimental Cell Research, 295(2), pp. 387-394. (doi: 10.1016/j.yexcr.2004.02.004)
Dalby, M.J. , Pasqui, D. and Affrossman, S. (2004) Cell response to nano-islands produced by polymer demixing: a brief review. IEE Proceedings: Nanobiotechnology, 151(2), pp. 53-61. (doi: 10.1049/ip-nbt:20040534)
Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Fibroblast response to a controlled nanoenvironment produced by colloidal lithography. Journal of Biomedical Materials Research Part A, 69A(2), pp. 314-322. (doi: 10.1002/jbm.a.20138)
Berry, C.C. , Charles, S., Wells, S., Dalby, M.J. and Curtis, A.S.G. (2004) The influence of transferrin stabilised magnetic nanoparticles on human dermal fibroblasts in culture. International Journal of Pharmaceutics, 269(1), pp. 211-225. (doi: 10.1016/j.ijpharm.2003.09.042)
Dalby, M.J. , Giannaras, D., Riehle, M.O. , Gadegaard, N. , Affrossman, S. and Curtis, A.S.G. (2004) Rapid fibroblast adhesion to 27 nm high polymer demixed nano-topography. Biomaterials, 25(1), pp. 77-83. (doi: 10.1016/S0142-9612(03)00475-7)
Curtis, A.S.G., Gadegaard, N. , Dalby, M.J. , Riehle, M.O. , Wilkinson, C.D.W. and Aitchison, G. (2004) Cells react to nanoscale order and symmetry in their surroundings. IEEE Transactions on NanoBioscience, 3(1), pp. 61-65. (doi: 10.1109/TNB.2004.824276)
Dalby, M.J. , Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A.S.G. (2004) Investigating the limits of filopodial sensing: a brief report using SEM to image the interaction between 10 nm high nano-topography and fibroblast filopodia. Cell Biology International, 28(3), pp. 229-236. (doi: 10.1016/j.cellbi.2003.12.004)
Dalby, M.J. , Riehle, M.O. , Sutherland, D.S., Agheli, H. and Curtis, A.S.G. (2004) Use of nanotopography to study mechanotransduction in fibroblasts – methods and perspectives. European Journal of Cell Biology, 83(4), pp. 159-169. (doi: 10.1078/0171-9335-00369)
Dalby, M.J. , Riehle, M.O. , Johnstone, H.J.H., Affrossman, S. and Curtis, A.S.G. (2003) Nonadhesive nanotopography: fibroblast response to poly(n-butyl methacrylate)-poly(styrene) demixed surface features. Journal of Biomedical Materials Research Part A, 67A(3), pp. 1025-1032. (doi: 10.1002/jbm.a.10139)
Dalby, M.J. , Riehle, M.O. , Yarwood, S.J., Wilkinson, C.D.W. and Curtis, A.S.G. (2003) Nucleus alignment and cell signaling in fibroblasts: response to a micro-grooved topography. Experimental Cell Research, 284(2), pp. 272-280. (doi: 10.1016/S0014-4827(02)00053-8)
da Silva, M.H.P., Soares, G.D.A., Elias, C.N., Best, S.M., Gibson, I.R., Disilvio, L. and Dalby, M.J. (2003) In vitro cellular response to titanium electrochemically coated with hydroxyapatite compared to titanium with three different levels of surface roughness. Journal of Materials Science: Materials in Medicine, 14, pp. 511-519.
Dalby, M. (2003) Enhanced HAPEX topography: Comparison of osteoblast response to established cement. Journal of Materials Science: Materials in Medicine, 14(8), pp. 693-696. (doi: 10.1023/A:1024959632082)
Dalby, M., Childs, S., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2003) Fibroblast reaction to island topography: changes in cytoskeleton and morphology with time. Biomaterials, 24, pp. 927-935.
Opara, T., Dalby, M. , Harper, E., Di Silvio, L. and Bonfield, W. (2003) The effect of varying percentage hydroxyapatite in poly(ethylmethacrylate) bone cement on human osteoblast-like cells. Journal of Materials Science: Materials in Medicine, 14, pp. 277-282.
Riehle, M.O. , Dalby, M.J., Johnstone, H., MacIntosh, A. and Affrossman, S. (2003) Cell behaviour of rat calvaria bone cells on surfaces with random nanometric features. Materials Science and Engineering C: Biomimetic and Supramolecular Systems, 23(3), pp. 337-340. (doi: 10.1016/S0928-4931(02)00282-5)
Dalby, M. (2002) New acrylic bone cements conjugated to vitamin E: Curing parameters, properties, and biocompatibility. Journal of Biomedical Materials Research Part A, 62(2), pp. 299-307. (doi: 10.1002/jbm.10296)
Dalby, M.J. , Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2002) Polymer-demixed nanotopography: Control of fibroblast spreading and proliferation. Tissue Engineering, 8, pp. 1099-1108.
Dalby, M. , Di Silvio, L., Gurav, N., Annaz, B., Kayser, M. and Bonfield, W. (2002) Optimizing HAPEX (TM) topography influences osteoblast response. Tissue Engineering, 8, pp. 453-467.
Dalby, M. , Di Silvio, L., Harper, E. and Bonfield, W. (2002) In vitro adhesion and biocompatability of osteoblast-like cells to poly(methylmethacrylate) and poly(ethylmethacrylate) bone cements. Journal of Materials Science: Materials in Medicine, 13, pp. 311-314.
Dalby, M. , Di Silvio, L., Harper, E. and Bonfield, W. (2002) Increasing hydroxyapatite incorporation into poly(methylmethacrylate) cement increases osteoblast adhesion and response. Biomaterials, 23, pp. 569-576.
Dalby, M. , Kayser, M., Bonfield, W. and Di Silvio, L. (2002) Initial attachment of osteoblasts to an optimised HAPEX (TM) topography. Biomaterials, 23, pp. 681-690.
Dalby, M., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtis, A. (2002) In vitro reaction of endothelial cells to polymer demixed nanotopography. Biomaterials, 23, pp. 2945-2954.
Dalby, M., Yarwood, S., Riehle, M.O. , Johnstone, H., Affrossman, S. and Curtsi, A. (2002) Increasing fibroblast response to materials using nanotopography: morphological and genetic measurements of cell response to 13-nm-high polymer demixed islands. Experimental Cell Research, 276, pp. 1-9. (doi: 10.1006/EXCR.2002.5498)
Di Silvio, L., Dalby, M. and Bonfield, W. (2002) Osteoblast behaviour on HA/PE composite surfaces with different HA volumes. Biomaterials, 23, pp. 101-107.
Dalby, M. , Di Silvio, L., Harper, E. and Bonfield, W. (2001) Initial interaction of osteoblasts with the surface of a hydroxyapatite-poly(methylmethacrylate) cement. Biomaterials, 22, pp. 1739-1747.
Book Sections
Trujillo, S. , Dobre, O. , Dalby, M. J. and Salmeron-Sanchez, M. (2019) Mechanotransduction and growth factor signaling in hydrogel-based microenvironments. In: Encyclopedia of Tissue Engineering and Regenerative Medicine. Elsevier, pp. 87-101. ISBN 9780128137000 (doi: 10.1016/B978-0-12-801238-3.11141-9)
Harper, M. M., Connolly, M. L., Goldie, L., Irvine, E. J., Shaw, J. E., Jayawarna, V., Richardson, S. M., Dalby, M. J. , Lightbody, D. and Ulijn, R. V. (2018) Biogelx: cell culture on self-assembling peptide gels. In: Nilsson, B. L. and Doran, T. M. (eds.) Peptide Self-Assembly: Methods and Protocols. Series: Methods in molecular biology (1777). Humana Press: New York, NY, pp. 283-303. ISBN 9781493978090 (doi: 10.1007/978-1-4939-7811-3_18)
Anderson, H., Llopis-Hernandez, V. , Sweeten, P., Donnelly, H., Gurden, R., Orapiriyakul, W., Salmeron-Sanchez, M. , Dalby, M.J. and Tsimbouri, M.P. (2017) Nanoscale surface cues and cell behaviour. In: Hashmi, S. (ed.) Reference Module in Materials Science and Materials Engineering. Elsevier. ISBN 9780128035818 (doi: 10.1016/B978-0-12-803581-8.10226-7)
Nikukar, H., Reid, S., Riehle, M.O. , Curtis, A.S.G. and Dalby, M.J. (2015) Control of mesenchymal stem-cell fate by engineering the nanoenvironment. In: Baharvand, H. and Aghdami, N. (eds.) Stem-Cell Nanoengineering. Wiley Blackwell: Hoboken, NJ, pp. 205-221. ISBN 9781118540619 (doi: 10.1002/9781118540640.ch12)
Tsimbouri, P. M. , McNamara, L. E., Alakpa, E. V., Dalby, M. J. and Turner, L.-A. (2015) Cell material interactions. In: van Blitterswijk, C. A. and de Boer, J. (eds.) Tissue Engineering. Elsevier, pp. 217-251. ISBN 9780124202108 (doi: 10.1016/B978-0-12-420145-3.00007-9)
Conference or Workshop Item
Tsimbouri, P.M. , Holloway, N., Fisher, L., Sjostrom, T., Nobbs, A.H., Meek, R.M.D., Su, B. and Dalby, M.J. (2016) Osteogenic and Bactericidal Surfaces from Hydrothermal Titania Nanowires on Titanium Substrates. The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016.
Alakpa, E., Burgess, K., Chung, P., Dalby, M. and Cusack, M. (2015) Topographical Bridging Between Bone and Nacre. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden, 24-27th Jun 2015.
Alakpa, E. et al. (2015) Selection of Lineage Guiding Metabolites in Stem Cell Cultures. International Society for Stem Cell Research (ISSCR), Stockholm, Sweden, 24-27th Jun 2015.
Alakpa, E., Burgess, K., Dalby, M. and Cusack, M. (2014) Investigating the 'Bone-Shell Divide': Pearl Oyster Shell Topography as a Means of Directing Stem Cell Behaviour. European Society for Biomaterials (ESB 2014), Liverpool, UK, 31st Aug–3rd Sep 2014. (Unpublished)
Alakpa, E., Jayawarna, V., Burgess, K., Ulijn, R. and Dalby, M. (2013) Combining Hydrogels With Tuned Stiffness and Metabolomics to Identify Small Molecules that Drive Mesenchymal Stem Cell Differentiation. European Materials Research Society (E-MRS), Strasbourg, France, 27-31 May 2013.
Alakpa, E.V., Burgess, K., Jayawarna, V., Ulijn, R. and Dalby, M. (2012) Development of Biomaterials for Cellular Differentiation Using a Metabolomics Approach. 3rd TERMIS World Congress, Vienna, Austria, 5-8 Sep 2012. p. 238.
Conference Proceedings
Young, P.S., Greer, A.I.M. , Tsimbouri, P.M. , Meek, R.M.D., Gadegaard, N. and Dalby, M.J. (2016) Precision-Engineered Nanotopographical Surfaces to Control Osteoclast Differentiation. In: The British Orthopaedic Research Society (BORS) Annual Conference, Glasgow, UK, 5-6 Sept 2016,
Silverwood, R.K., Fairhurst, P., Tsimbouri, P. , Sjostrom, T., Young, P., Su, B., Meek, R.M.D. and Dalby, M. (2014) Analysis of Osteoclastogenesis/Osteoblastogenesis Using Human Bone Marrow Derived Co-Cultures on Nanotopographical Titania Surfaces. In: Glasgow Meeting of Orthopaedic Research (GLAMOR), Glasgow, UK, 28 Mar 2014,
Khokhar, A.Z., Tsimbouri, P.M. , Dalby, M.J. and Gadegaard, N. (2011) Development of ultra-hard stamps for titanium patterning. In: 37th International Conference on Micro and Nano Engineering: MNE 2011, Berlin, 19 - 23 September 2011,
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Engineering the bone marrow niche to control stem cell regulation, metastaticevolution and cancer dormancy
Engineering and Physical Sciences Research Council
2023 - 2028
- Mechanobiology-based medicine - Phase 2
Engineering and Physical Sciences Research Council
2023 - 2028
- PRISM-LT - PRInted Symbiotic Materials as a dynamic platform for Living Tissues production
Innovate EU Guarantee
2022 - 2027
- Nanovibrated chondrocytes
Engineering and Physical Sciences Research Council
2022 - 2025
- Joint CDT and TCES Conference Future Leaders in Regenerative Medicine
Engineering and Physical Sciences Research Council
2022 - 2022
- MRC Ageing across the life course interdisciplinary research network
Biotechnology and Biological Sciences Research Council
2022 - 2024
- Mechanobiology-based medicine
Engineering and Physical Sciences Research Council
2021 - 2022
- Validation of an artificial in vitro humanised 3D haemopoietic system to investigate haematological malignancies.
National Centre for the Replacement of Animals Research
2021 - 2024
- HEALIKICK
European Commission
2020 - 2025
- Engineered haematopoietic stem cell niches for disease modelling
National Centre for the Replacement of Animals Research
2020 - 2020
- EPSRC Centre for Multiscale soft tissue mechanics with MIT and POLIMI (SofTMech-MP)
Engineering and Physical Sciences Research Council
2020 - 2023
- Engineered substrates for the isolation and expansion of mesenchymal stem cells
Leverhulme Trust
2019 - 2022
- Developing the nanokick bioreactor for commercialisation and cell therapy
Biotechnology and Biological Sciences Research Council
2019 - 2021
- A novel tool for veterinary bone regeneration
Biotechnology and Biological Sciences Research Council
2019 - 2019
- Cell Guidance Systems KTP
Innovate UK
2019 - 2021
- In vitro and in vivo studies of 3D orthopaedic implants with cell-instructive nanotopographies
Medical Research Council
2019 - 2022
- Early diagnosis and intervention of osteoporosis using nanovibrational stimulation
Science and Technology Facilities Council
2018 - 2020
- Nanoparticle-Mediated microRNA Delivery for Increased Osteogenesis in a 3D Osteoporotic Bone Marrow Model.
Chief Scientist Office (CSO)
2018 - 2020
- NANOSCALE VIBRATIONS TO MODULATE OSTEOGENESIS AND IMMUNE RESPONSE
Royal College of Surgeons of Edinburgh
2017 - 2018
- Robertson Trust Award
Royal College of Surgeons of Edinburgh
2017 - 2018
- Rapid Bone Graft Synthesis Through Dual Piezoelectric/Nanomechaniocal Stimulation
Biotechnology and Biological Sciences Research Council
2017 - 2020
- Materials exploitation of the biointerface to control MSC quality and niche phenotype
Biotechnology and Biological Sciences Research Council
2017 - 2019
- Working together - combined technologies for robust engineering of bone grafts with controlled geometry
Find A Better Way
2017 - 2021
- Engineering growth factor microenvironments- a new therapeutic paradigm for regenerative medicine
Engineering and Physical Sciences Research Council
2016 - 2021
- Development of NanoKick Bioreactor
Biotechnology and Biological Sciences Research Council
2016 - 2017
- Developing the NanoKick bioreactor to enable tissue engineered bone graft and use of metabolomics to identify bone specific drug candidates
Engineering and Physical Sciences Research Council
2016 - 2019
- The effect of precision engineered nanoscale topography on osteoclast differentiation and activity in orthopaedic polymers
Royal College of Surgeons of Edinburgh
2016 - 2017
- Living interfaces based on non-pathogenic bacterial to control stem cell differentiation
Leverhulme Trust
2015 - 2018
- Commercialisation and exploitation of a bone bioreactor - nanoforce
Biotechnology and Biological Sciences Research Council
2015 - 2015
- The effect of precision engineered nanoscale topography on osteoclast differentiation and activity in orthopaedic polymers
NHS Argyll and Clyde
2015 - 2017
- Using nanokicking to discover and exploit differences in mechanical response between normal and cancerous cells
Bone Cancer Research Trust
2015 - 2015
- STFC-IAA: Consultant to advise on Pharmaceutical Industry Market for NaonoKick technology
Science and Technology Facilities Council
2015 - 2017
- Synergistic microenvironments for non-union bone defects
Medical Research Council
2014 - 2016
- Nanoniche - The use of microRNAs and nanotopography to modulate skeletal stem cell fate and function
Biotechnology and Biological Sciences Research Council
2014 - 2017
- Nanoparticles and nanotopography: a nano-toolbox to control stem cell self-renewal via microRNAs
Biotechnology and Biological Sciences Research Council
2014 - 2016
- The role of insulin-dependent signalling pathways in the control of Mesenchymal stem cell differentiation twoards bone and fat
Tenovus Scotland
2014 - 2016
- Development of nanopatterned substrates for the delivery of high quality stem cells
Biotechnology and Biological Sciences Research Council
2013 - 2016
- Stem Cells metabolomics for bone therapies and tissue engineering.
Medical Research Council
2013 - 2016
- Multiscale topographical modulation of cells and bacteria for next generation orthopaedic implants
Engineering and Physical Sciences Research Council
2013 - 2016
- A Novel 3D Bone Regeneration Scaffold
AO Foundation
2013 - 2015
- Dynamic surfaces to mimic mesenchymal stem cell niche functions
Biotechnology and Biological Sciences Research Council
2013 - 2016
- Microfluidic fibre extrusion for bone replacement
Biotechnology and Biological Sciences Research Council
2013 - 2014
- EPSRC-IAA: CS analogs for controlled MSC differentiation
Engineering and Physical Sciences Research Council
2012 - 2017
- Biomimetic ceramic topographies for improved osseointegration
British Orthopaedic Association
2012 - 2013
- Nanotopography directed stem cell fate
British Orthopaedic Association
2012 - 2012
- Bioactive orthopaedic implants using nanopatterned 3D materials
Medical Research Council
2011 - 2014
- Tissue engineering of living bone graft in vitro for orthopaedic application
Chief Scientist Office
2010 - 2012
- KTA - EPSRC: Nanostructured Substrates for Cell and Tissue Engineering
Engineering and Physical Sciences Research Council
2009 - 2012
- KTA EPSRC: Nanotopographics for control of stem cell growth
Engineering and Physical Sciences Research Council
2009 - 2012
- KTA-EPSRC: Developing nanofibrous materials for stem cells - new platforms for in vitro manipulation and in vivo tissue regeneration.
Engineering and Physical Sciences Research Council
2009 - 2012
- Micro- and nano-patterning of titanium surfaces for optimal osseointegration of orthopaedic implants
Engineering and Physical Sciences Research Council
2009 - 2012
- Stem Cell Differentiation & Genomic Processes in Response to Bioactive Nanotopography
Biotechnology and Biological Sciences Research Council
2009 - 2012
- Optimising Cell Culture Plasticware for use in Biochemical Understanding of Stem Cell Behaviour
Biotechnology and Biological Sciences Research Council
2008 - 2009
- Optimising nanodisorder for bone tissue engineering
Biotechnology and Biological Sciences Research Council
2006 - 2007
- Nanobiomimetics for bone tissue engineering - osteoblast and osteoprogenitor adhesion and differentiation
AO Foundation
2005 - 2007
- Nano-Biomimetics for Bone Tissue Engineering: progenitor cell adhesion and differentiation
Biotechnology and Biological Sciences Research Council
2003 - 2008
Supervision
- Duncan, Elaine
Bioengineering 3D Adipose Organoids for Type 2 Diabetes Drug Discovery - McNicol, Gordon
Mathematical models for cell-substrate interaction - Negi, Deepti
Arrival of the fittest: examining the underlying mechanisms of fish bone development - Owen, Zachary
Acoustofluidics to Assist Real Time Mass Spectrometry Analysis of Microfluidic Picodroplets in Biotechnological and/or Biochemical Applications - Sardar, Sabah
Identification of biophysical markers for Chronic intestinal pseudo-obstruction disease
Teaching
- Level 3 - Cell culture lab
- Level 4 - Cell and Tissue Engineering option
- Level 4 - Biotechnology option
- Level 4 - Stem Cell option
- Level 4 - co-ordinator, Stem Cell option
Research datasets
2022
Salmeron-Sanchez, M. , Petaroudi, M., Rodrigo-Navarro, A. , Dobre, O. and Dalby, M. (2022) Living Biomaterials to Engineer Hematopoietic Stem Cell Niches. [Data Collection]
2021
Kennedy, J., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P., Reid, S., Young, P., Meek, D., Goodyear, C. and Dalby, M. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. [Data Collection]
Damiati, L. , Tsimbouri, M. , Eales, M., Jayawarna, V., Xiao, Y., Li, P. , Burgess, K., Wells, J., Meek, R.M. D., Oreffo, R. O. C., Nobbs, A., Ramage, G. , Salmeron-Sanchez, M. and Dalby, M. (2021) Materials-driven fibronectin assembly on nanoscale topography enhances mesenchymal stem cell adhesion, protecting cells from bacterial virulence factors and preventing biofilm formation. [Data Collection]
Kennedy, J., Tsimbouri, M. , Campsie, P., Sood, S., Childs, P. G., Reid, S., Young, P., Meek, D. R. M., Goodyear, C. S. and Dalby, M. (2021) Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures. [Data Collection]
2020
Orapiriyakul, W., Tsimbouri, M. , Childs, P., Campsie, P., Wells, J., Fernandez-Yague, M. A., Burgess, K., Tanner, E., Tassieri, M. , Meek, D., Vassalli, M. , Biggs, M. J.P., Salmeron-Sanchez, M. , Oreffo, R. O. C., Reid, S. and Dalby, M. (2020) Nanovibrational Stimulation of Mesenchymal Stem Cells Induces Therapeutic Reactive Oxygen Species and Inflammation for Three- Dimensional Bone Tissue Engineering. [Data Collection]
Hodgkinson, T., Tsimbouri, M. , Llopis-Hernandez, V. , Campsie, P., Scurr, D., Childs, P., Phillips, D. , Donnelly, S., Wells, J., Salmeron-Sanchez, M. , Burgess, K., Alexander, M., Vassalli, M. , Oreffo, R., Reid, S., France, D. and Dalby, M. (2020) Nanovibrational mesenchymal stem cell stimulation allows detection of highly osteo-specific bioactive metabolites that can be modified for enhanced potency. [Data Collection]
Ross, E., Turner, L.-A., Saeed, A., DONNELLY, H., Burgess, K., Blackburn, G., Reynolds, P., Wells, J., Mountford, J., Gadegaard, N. , Oreffo, R., Salmeron-Sanchez, M. and Dalby, M. (2020) Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells during large-scale expansion. [Data Collection]
2019
DONNELLY, H., Smith, C.-A., Sweeten, P., Gadegaard, N. , Meek, R. M. D., D'Este, M., Mata, A., Eglin, E. and Dalby, M. (2019) Bone and cartilage differentiation of a single stem cell population driven by material interface. [Data Collection]
2018
Sprott, M., Gallego-Ferrer, G., Dalby, M. , Salmeron-Sanchez, M. and Cantini, M. (2018) Functionalisation of PLLA with Polymer Brushes to Trigger the Assembly of Fibronectin into Nanonetworks. [Data Collection]
2017
Tsimbouri, P. , Childs, P., Pemberton, G. D., Yang, J., Jayawarna, V., Orapiriyakul, W., Burgess, K., Gonzalez-Garcia, C., Blackburn, G., Thomas, D., Giraldo, C. V., Biggs, M. J. P., Curtis, A., Salmerón-Sanchez, M., Reid, S. and Dalby, M. (2017) Stimulation of 3D osteogenesis by mesenchymal stem cells via a nanovibrational bioreactor. [Data Collection]
Alakpa, E. V., Burgess, K., Chung, P., Riehle, M. , Gadegaard, N. , Dalby, M. and Cusack, M. (2017) Nacre topography produces higher crystallinity in bone than chemically-induced osteogenesis. [Data Collection]
Moulisova, V. , Gonzalez-Garcia, C., Cantini, M. , Rodrigo-Navarro, A. , Weaver, J., Costello, M., Sabater i Serra, R., Dalby, M. , Garcia, A. and Salmerón-Sánchez, M. (2017) Engineered microenvironments for synergistic VEGF - Integrin signalling during vascularization. [Data Collection]
2016
Lee, L., Gadegaard, N. , Andrés, M. C. d., Turner, L.-A., Burgess, K., Yarwood, S., Wells, J., Mpoyi, E., Salmerón-Sánchez, M., Meek, R. D., Oreffo, R. and Dalby, M. (2016) Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency. [Data Collection] (Unpublished)
Rico Tortosa, P., Mnatsakanyan, H., Dalby, M. and Salmerón-Sánchez, M. (2016) Material-Driven Fibronectin Assembly Promotes Maintenance of Mesenchymal Stem Cell Phenotypes. [Data Collection]
Ngandu Mpoyi, E., Cantini, M. , Reynolds, P. , Gadegaard, N. , Dalby, M. and Salmerón-Sánchez, M. (2016) Protein adsorption as a key mediator in the nanotopographical control of cell behavior. [Data Collection]
Roberts, J. , Sahoo, J. , McNamara, L., Burgess, K. , Yang, J., Alakpa, E. , Anderson, H. , Hay, J., Turner, L.-A., Yarwood, S., Zelzer, M. , Oreffo, R., Ulijn, R. and Dalby, M. (2016) Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation. [Data Collection] (Unpublished)
Silverwood, R. K., Fairhurst, P. G., Sjöström, T., Welsh, F., Sun, Y., Li, G., Yu, B., Young, P. S., Su, B., Meek, R. M.D., Dalby, M. J. and Tsimbouri, P. M. (2016) Analysis of osteoclastogenesis / osteoblastogenesis on nanotopographical titania surfaces. [Data Collection]
Tsimbouri, P. , Fisher, L., Holloway, N., Sjöström, T., Nobbs, A.H., Meek, R. M.D., Su, B. and Dalby, M. (2016) Osteogenic and bactericidal surfaces from hydrothermal titania nanowires on titanium substrates. [Data Collection] (Unpublished)
2015
Alakpa, E. V., Jayawarna, V., Burgess, K. V., West, C. C., Bakker, S. C.J., Roy, S., Javid, N., Fleming, S., Lamprou, D. A., Yang, J., Miller, A., Urquhart, A. J., Frederix, P. W.J.M., Hunt, N. T., Péault, B., Ulijn, R. V. and Dalby, M. J. (2015) Using tunable hydrogels for selection of lineage guiding metabolites in stem cell cultures. [Data Collection]
Additional information
Editorial Board
- 2009 - present: Journal of Tissue Engineering
- 2007 - present: Open Biomedical Engineering Journal
- 2005 - present: Nanomedicine - Associate Editor from 2010, Expert Committee from 2009
- 2005 - present: Current Stem Cell Research and Therapy
- 2004 - present: European Cells & Materials
Grant Advisory Board
- 2003 - present: EPSRC - Member of Peer Review College
Invited International Presentations
- 2013: London, England, UK - "Mesenchymal stem cell response to nanotopographical features (and a few other nanoscale things)", Queen Mary, University of London
- 2013: Cardiff, Wales, UK - "Nanotopographical (and other nano stuff) control of mesenchymal stem cell mechanotransduction and fate", British Society for Matrix Biology
- 2012: Cambridge, England, UK - "Mesenchymal stem cell response to nanotopographical features (and a few other nanoscale things)", Cavendish Laboratories, University of Cambridge
- 2012: Manchester, England, UK - "Nanotopographical stimulation of Mesenchymal Stem Cells", British Neuroscience Association Meeting
- 2011: Dublin, Ireland - "Nanotopographical Surfaces to Influence Mesenchymal Stem Cell Differentiation and Self-Renewal", European Society for Biomaterials
- 2011: Manchester, England, UK - "Nanotopographical Surfaces for Mesenchymal Stem Cells", Stem Cell Seminar Series
- 2011: Edinburgh, Scotland, UK - "Nanotopographical Surfaces to Influence Mesenchymal Stem Cell Differentiation and Self-Renewal", European Stem Cells Meeting
- 2010: Bath, England, UK - "Nanoengineered materials for tissue engineering and as a tool to help understand mechanotransduction", Centre for Regenerative Medicine Meeting, University of Bath
- 2010: Bristol, England, UK - "Nanoengineered materials for tissue engineering and as a tool to help understand mechanotransduction", University of Bristol Nanoscience Seminar Series
- 2010: Galway, Ireland - Invited Talk and Session Chair, TERMIS 2010
- 2010: Glasgow, Scotland, UK - Organiser, 1st Glasgow Orthopaedic Research Initiative Meeting
- 2010: Manchester, England, UK - Session Chair, Tissue and Cell Engineering Society Meeting
- 2009: Glasgow, Scotland, UK - Organiser, Tissue and Cell Engineering Meeting
- 2009: Milton Keynes, England, UK - "Engineered materials for tissue engineering and as a tool to help understand mechanotransduction", Open University Seminar Series
- 2009: Keele, England, UK - "Engineered materials for tissue engineering and as a tool to help understand mechanotransduction", Surface Science of Biologically Important Materials Meeting, University of Keele
- 2008: Cambridge, England, UK - "Engineered materials for tissue engineering and as a tool to help understand mechanotransduction", University of Cambridge Gordon Seminar
- 2008: Manchester, England, UK - "Engineered materials for tissue engineering and as a tool to help understand mechanotransduction", Manchester Integrating Medicine and Innovative Technology Seminar
- 2008: Nottingham, England, UK - Chair, Tissue and Cell Engineering Society Meeting
- 2007: London, England, UK - Chair, Tissue and Regenerative Medicine International Society World Meeting
- 2007: London, England, UK - "Topography as a tool to study mechanotransduction", University College London Seminar Series
- 2007: Nottingham, England, UK - "Topography as a tool to study mechanotransduction", University of Nottingham Seminar Series
- 2006: Edinburgh, Scotland, UK - "Nanotopography and Mesenchymal Stem Cell Differentiation", European Nano Trade Alliance
- 2006: Sheffield, England, UK - "Nanotopographical Stem Cell Cell Engineering and Topographical Mechanotransduction", Tissue and Cell Engineering Society
- 2006: Canterbury, England, UK - "Nanotopographical Stimulation of Mesenchymal Stem Cells", Society for Experimental Biology
- 2005: Birmingham, England, UK - "Nanotopography as a Novel Strategy for Therapeutic Developments", British and German Societies for Rheumatology Joint Meeting
- 2005: Birmingham, England, UK - "Nanotopography as a novel strategy for therapeutic developments", joint meeting of the British Society for Rheumatology, the Deutsche Gesellschaft fur Rheumatologie and the Bone and Tooth Society
- 2005: Aberdeen, Scotland, UK - "Evidence for Topographically Induced Mechanotransduction in Fibroblasts'", Biomedical Sciences seminar programme, University of Aberdeen
- 2005: Glasgow, Scotland, UK - "Nanobiomimetic Mechanotransduction in Fibroblasts and Osteoprogenitor Cells", Bone Regeneration Summit
- 2004: Liverpool, England, UK - "Topographical Influences in Tissue Engineering Scaffolds", Engineering in Regenerative Medicine Meeting, Royal Academy of Engineering
- 2003: London, England, UK - "Nano-Biomimetics For Bone Tissue Engineering Progenitor Cell Adhesion and Differentiation", 17th Scientific Meeting on Tissue Engineering
Prizes, Awards and Distinctions
- 2007: President's Medal of the Society of Experimental Biology
- 2007: Nexxus Young Life Scientist of the Year Award
- 2006: Tissue and Cell Engineering Society's Early Stage Investigator Award
- 2003: Saving British Science Society Award at SET for Britain Nanotechnology Meeting, Houses of Parliament
Professional Learned Society
- 2010 - present: Glasgow Orthopaedic Research Initiative - Academic Secretary
- 2003 - present: Tissue and Cell Engineering Society - Elected to the committee
Research Fellowship
- 2003 - 2008: BBSRC David Phillips Fellowship
