Professor Christina Cobbold

  • Professor of Mathematical Biology (Mathematics)
  • Associate (Institute of Biodiversity Animal Health & Comparative Medicine)

Research interests

My research interests are in mathematical biology, with a focus on spatial and evolutionary ecology. This involves interdisciplinary collaborations with biologists to develop, apply and analyse mathematical models in order to better understand population processes. I am particularly interested in assessing the effect of habitat fragmentation on species survival and the effect of environmental variation on the evolution and adaptation of life-history traits such as developmental timing. Mathematical approaches include analytical methods for dynamical systems, perturbation theory, and computational methods. Increasingly I have also become interested in formulating and testing quantitative models of biological and antigenic diversity.

Research units

Publications

List by: Type | Date

Jump to: 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2005 | 2002 | 2001 | 2000
Number of items: 34.

2021

Brass, D. P., Cobbold, C. A. , Ewing, D. A., Purse, B. V., Callaghan, A. and White, S. M. (2021) Phenotypic plasticity as a cause and consequence of population dynamics. Ecology Letters, (Accepted for Publication)

Ewing, D. A., Purse, B. V., Cobbold, C. A. and White, S. M. (2021) A novel approach for predicting risk of vector-borne disease establishment in marginal temperate environments under climate change: West Nile virus in the UK. Journal of the Royal Society: Interface, 18(178), 20210049. (doi: 10.1098/rsif.2021.0049) (PMID:34034529) (PMCID:PMC8150030)

2020

Mittell, E. A., Cobbold, C. A. , Ijaz, U. Z. , Kilbride, E. A., Moore, K. A. and Mable, B. K. (2020) Feral populations of Brassica oleracea along Atlantic coasts in western Europe. Ecology and Evolution, 10(20), pp. 11810-11825. (doi: 10.1002/ece3.6821) (PMID:33145003) (PMCID:PMC7593181)

Cobbold, C. A. and Stana, R. (2020) Should I stay or should I go: partially sedentary populations can outperform fully dispersing populations in response to climate-induced range shifts. Bulletin of Mathematical Biology, 82, 26. (doi: 10.1007/s11538-020-00700-7) (PMID:32006139) (PMCID:PMC6994560)

2019

Buckley, J., Daly, R. , Cobbold, C. A. , Burgess, K. and Mable, B. K. (2019) Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses. Proceedings of the Royal Society of London Series B: Biological Sciences, 286(1915), 20192109. (doi: 10.1098/rspb.2019.2109) (PMID:31744436) (PMCID:PMC6892046)

Hurford, A., Cobbold, C. A. and Molnár, P. K. (2019) Skewed temperature dependence affects range and abundance in a warming world. Proceedings of the Royal Society of London Series B: Biological Sciences, 286(1908), 20191157. (doi: 10.1098/rspb.2019.1157) (PMID:31387510) (PMCID:PMC6710591)

Jayaraman, S. et al. (2019) Application of long read sequencing to determine expressed antigen diversity in Trypanosoma brucei infections. PLoS Neglected Tropical Diseases, 13(4), e0007262. (doi: 10.1371/journal.pntd.0007262) (PMID:30943202) (PMCID:PMC6464242)

Ewing, D. A., Cobbold, C. A. , Purse, B. V., Schafer, S. M. and White, S. M. (2019) Uncovering mechanisms behind mosquito seasonality by integrating mathematical models and daily empirical population data: Culex pipiens in the UK. Parasites and Vectors, 12, 74. (doi: 10.1186/s13071-019-3321-2) (PMID:30732629) (PMCID:PMC6367758)

2018

Yurk, B. P. and Cobbold, C. A. (2018) Homogenization techniques for population dynamics in strongly heterogeneous landscapes. Journal of Biological Dynamics, 12(1), pp. 171-193. (doi: 10.1080/17513758.2017.1410238) (PMID:29228877)

2017

McCulloch, R. , Cobbold, C. A. , Figueiredo, L., Jackson, A., Morrison, L. J., Mugnier, M. R., Papavasiliou, N., Schnaufer, A. and Matthews, K. (2017) Emerging challenges in understanding trypanosome antigenic variation. Emerging Topics in Life Sciences, 1(6), pp. 585-592. (doi: 10.1042/ETLS20170104) (PMID:30271884) (PMCID:PMC6162063)

Barraquand, F. et al. (2017) Moving forward in circles: challenges and opportunities in modelling population cycles. Ecology Letters, 20(8), pp. 1074-1092. (doi: 10.1111/ele.12789)

Bush, A. et al. (2017) Connecting Earth observation to high-throughput biodiversity data. Nature Ecology and Evolution, 1, 0176. (doi: 10.1038/s41559-017-0176)

2016

Ewing, D. A., Cobbold, C. A. , Nunn, M. A., Purse, B. V. and White, S. M. (2016) Modelling the effect of temperature on the seasonal population dynamics of temperate mosquitoes. Journal of Theoretical Biology, 400, pp. 65-79. (doi: 10.1016/j.jtbi.2016.04.008) (PMID:27084359)

Reeve, R. , Leinster, T., Cobbold, C. A. , Thompson, J., Brummitt, N., Mitchell, S. N. and Matthews, L. (2016) How to partition diversity. arXiv, (Unpublished)

2015

Cobbold, C. A. , Lutscher, F. and Sherratt, J. A. (2015) Diffusion-driven instabilities and emerging spatial patterns in patchy landscapes. Ecological Complexity, 24, pp. 69-81. (doi: 10.1016/j.ecocom.2015.10.001)

Cobbold, C. A. , Teng, J. and Muldowney, J. S. (2015) The influence of host competition and predation on tick densities and management implications. Theoretical Ecology, 8(3), pp. 349-368. (doi: 10.1007/s12080-015-0255-y)

Hughes, J. S., Cobbold, C. A. , Haynes, K. and Dwyer, G. (2015) The effects of forest spatial structure on insect outbreak dynamics: insights from host-parasitoid models. American Naturalist, 183(5), E130-E152. (doi: 10.1086/680860) (PMID:25905513)

2014

Cobbold, C. A. and Lutscher, F. (2014) Mean occupancy time: linking mechanistic movement models, population dynamics and landscape ecology to population persistence. Journal of Mathematical Biology, 68(3), pp. 549-579. (doi: 10.1007/s00285-013-0642-1)

Gjini, E. A., Haydon, D. T. , Barry, J. D. and Cobbold, C. A. (2014) Revisiting the diffusion approximation to estimate evolutionary rates of gene family diversification. Journal of Theoretical Biology, 341, pp. 111-122. (doi: 10.1016/j.jtbi.2013.10.001)

2013

Moran, E. V., Berwick, S. and Cobbold, C. A. (2013) Effects of plant genotype and insect dispersal rate on the population dynamics of a forest pest. Ecology, 94(12), pp. 2792-2802. (doi: 10.1890/12-1708.1)

Gjini, E., Haydon, D.T. , Barry, J.D. and Cobbold, C.A. (2013) Linking the antigen archive structure to pathogen fitness in African trypanosomes. Proceedings of the Royal Society of London Series B: Biological Sciences, 280(1753), p. 20122129. (doi: 10.1098/rspb.2012.2129)

2012

Leinster, T. and Cobbold, C. (2012) Measuring diversity: the importance of species similarity. Ecology, 93(3), pp. 477-489. (doi: 10.1890/10-2402.1)

Gjini, E., Haydon, D.T. , Barry, J.D. and Cobbold, C.A. (2012) The impact of mutation and gene conversion on the local diversification of antigen genes in African trypanosomes. Molecular Biology and Evolution, 29(11), pp. 3321-3331. (doi: 10.1093/molbev/mss166)

Higham, C.F., Morales, F., Cobbold, C.A. , Haydon, D.T. and Monckton, D.G. (2012) High levels of somatic DNA diversity at the myotonic dystrophy type 1 locus are driven by ultra-frequent expansion and contraction mutations. Human Molecular Genetics, 21(11), pp. 2450-2463. (doi: 10.1093/hmg/dds059)

2011

Cobbold, C.A. and Powell, J.A. (2011) Evolution stabilises the synchronising dynamics of poikilotherm life cylces. Bulletin of Mathematical Biology, 73(5), pp. 1052-1081. (doi: 10.1007/s11538-010-9552-1)

Hackett-Jones, E., White, A. and Cobbold, C.A. (2011) The evolution of developmental timing in natural enemy systems. Journal of Theoretical Biology, 275(1), pp. 1-11. (doi: 10.1016/j.jtbi.2010.12.040)

2010

Gjini, E., Haydon, D. , Barry, J. and Cobbold, C. (2010) Critical interplay between parasite differentiation, host immunity and antigenic variation in trypanosome infections. American Naturalist, 176(4), pp. 424-439. (doi: 10.1086/656276)

2009

Cobbold, C.A., Roland, J. and Lewis, M.A. (2009) The impact of parasitoid emergence time on host-parasitoid population dynamics. Theoretical Population Biology, 75(2-3), pp. 201-215. (doi: 10.1016/j.tpb.2009.02.004)

Hackett-Jones, E., Cobbold, C.A. and White, A. (2009) Coexistence of multiple parasitoids on a single host due to differences in parasitoid phenology. Theoretical Ecology, 2(1), pp. 19-31. (doi: 10.1007/s12080-008-0025-1)

Higham, C., Wilcox, D., Haydon, D. , Cobbold, C. and Monckton, D. (2009) Modelling dynamic DNA in mytonic dystrophy. In: Sixth International Workshop on Computational Systems Biology, WCSB 2009, Aarhus, Denmark, 10-12 Jun 2009, pp. 63-66.

2005

Cobbold, C.A., Lewis, M.A., Lutscher, F. and Roland, J. (2005) How parasitism affects critical patch-size in a host-parasitoid model: application to the forest tent caterpillar. Theoretical Population Biology, 67(2), pp. 109-125. (doi: 10.1016/j.tpb.2004.09.004)

2002

Cobbold, C.A., Sherratt, J.A. and Maxwell, S.R.J. (2002) Lipoprotein oxidation and its significance for atherosclerosis: a mathematical approach. Bulletin of Mathematical Biology, 64(1), pp. 65-95. (doi: 10.1006/bulm.2001.0267)

2001

Cobbold, C.A. (2001) The role of nitric oxide in the formation of keloid and hypertrophic lesions. Medical Hypotheses, 57(4), pp. 497-502. (doi: 10.1054/mehy.2001.1373)

2000

Cobbold, C.A. and Sherratt, J. A. (2000) Mathematical modelling of nitric oxide activity in wound healing can explain keloid and hypertrophic scarring. Journal of Theoretical Biology, 204(2), pp. 257-288. (doi: 10.1006/jtbi.2000.2012)

This list was generated on Tue Aug 3 20:29:41 2021 BST.
Number of items: 34.

Articles

Brass, D. P., Cobbold, C. A. , Ewing, D. A., Purse, B. V., Callaghan, A. and White, S. M. (2021) Phenotypic plasticity as a cause and consequence of population dynamics. Ecology Letters, (Accepted for Publication)

Ewing, D. A., Purse, B. V., Cobbold, C. A. and White, S. M. (2021) A novel approach for predicting risk of vector-borne disease establishment in marginal temperate environments under climate change: West Nile virus in the UK. Journal of the Royal Society: Interface, 18(178), 20210049. (doi: 10.1098/rsif.2021.0049) (PMID:34034529) (PMCID:PMC8150030)

Mittell, E. A., Cobbold, C. A. , Ijaz, U. Z. , Kilbride, E. A., Moore, K. A. and Mable, B. K. (2020) Feral populations of Brassica oleracea along Atlantic coasts in western Europe. Ecology and Evolution, 10(20), pp. 11810-11825. (doi: 10.1002/ece3.6821) (PMID:33145003) (PMCID:PMC7593181)

Cobbold, C. A. and Stana, R. (2020) Should I stay or should I go: partially sedentary populations can outperform fully dispersing populations in response to climate-induced range shifts. Bulletin of Mathematical Biology, 82, 26. (doi: 10.1007/s11538-020-00700-7) (PMID:32006139) (PMCID:PMC6994560)

Buckley, J., Daly, R. , Cobbold, C. A. , Burgess, K. and Mable, B. K. (2019) Changing environments and genetic variation: natural variation in inbreeding does not compromise short-term physiological responses. Proceedings of the Royal Society of London Series B: Biological Sciences, 286(1915), 20192109. (doi: 10.1098/rspb.2019.2109) (PMID:31744436) (PMCID:PMC6892046)

Hurford, A., Cobbold, C. A. and Molnár, P. K. (2019) Skewed temperature dependence affects range and abundance in a warming world. Proceedings of the Royal Society of London Series B: Biological Sciences, 286(1908), 20191157. (doi: 10.1098/rspb.2019.1157) (PMID:31387510) (PMCID:PMC6710591)

Jayaraman, S. et al. (2019) Application of long read sequencing to determine expressed antigen diversity in Trypanosoma brucei infections. PLoS Neglected Tropical Diseases, 13(4), e0007262. (doi: 10.1371/journal.pntd.0007262) (PMID:30943202) (PMCID:PMC6464242)

Ewing, D. A., Cobbold, C. A. , Purse, B. V., Schafer, S. M. and White, S. M. (2019) Uncovering mechanisms behind mosquito seasonality by integrating mathematical models and daily empirical population data: Culex pipiens in the UK. Parasites and Vectors, 12, 74. (doi: 10.1186/s13071-019-3321-2) (PMID:30732629) (PMCID:PMC6367758)

Yurk, B. P. and Cobbold, C. A. (2018) Homogenization techniques for population dynamics in strongly heterogeneous landscapes. Journal of Biological Dynamics, 12(1), pp. 171-193. (doi: 10.1080/17513758.2017.1410238) (PMID:29228877)

McCulloch, R. , Cobbold, C. A. , Figueiredo, L., Jackson, A., Morrison, L. J., Mugnier, M. R., Papavasiliou, N., Schnaufer, A. and Matthews, K. (2017) Emerging challenges in understanding trypanosome antigenic variation. Emerging Topics in Life Sciences, 1(6), pp. 585-592. (doi: 10.1042/ETLS20170104) (PMID:30271884) (PMCID:PMC6162063)

Barraquand, F. et al. (2017) Moving forward in circles: challenges and opportunities in modelling population cycles. Ecology Letters, 20(8), pp. 1074-1092. (doi: 10.1111/ele.12789)

Bush, A. et al. (2017) Connecting Earth observation to high-throughput biodiversity data. Nature Ecology and Evolution, 1, 0176. (doi: 10.1038/s41559-017-0176)

Ewing, D. A., Cobbold, C. A. , Nunn, M. A., Purse, B. V. and White, S. M. (2016) Modelling the effect of temperature on the seasonal population dynamics of temperate mosquitoes. Journal of Theoretical Biology, 400, pp. 65-79. (doi: 10.1016/j.jtbi.2016.04.008) (PMID:27084359)

Reeve, R. , Leinster, T., Cobbold, C. A. , Thompson, J., Brummitt, N., Mitchell, S. N. and Matthews, L. (2016) How to partition diversity. arXiv, (Unpublished)

Cobbold, C. A. , Lutscher, F. and Sherratt, J. A. (2015) Diffusion-driven instabilities and emerging spatial patterns in patchy landscapes. Ecological Complexity, 24, pp. 69-81. (doi: 10.1016/j.ecocom.2015.10.001)

Cobbold, C. A. , Teng, J. and Muldowney, J. S. (2015) The influence of host competition and predation on tick densities and management implications. Theoretical Ecology, 8(3), pp. 349-368. (doi: 10.1007/s12080-015-0255-y)

Hughes, J. S., Cobbold, C. A. , Haynes, K. and Dwyer, G. (2015) The effects of forest spatial structure on insect outbreak dynamics: insights from host-parasitoid models. American Naturalist, 183(5), E130-E152. (doi: 10.1086/680860) (PMID:25905513)

Cobbold, C. A. and Lutscher, F. (2014) Mean occupancy time: linking mechanistic movement models, population dynamics and landscape ecology to population persistence. Journal of Mathematical Biology, 68(3), pp. 549-579. (doi: 10.1007/s00285-013-0642-1)

Gjini, E. A., Haydon, D. T. , Barry, J. D. and Cobbold, C. A. (2014) Revisiting the diffusion approximation to estimate evolutionary rates of gene family diversification. Journal of Theoretical Biology, 341, pp. 111-122. (doi: 10.1016/j.jtbi.2013.10.001)

Moran, E. V., Berwick, S. and Cobbold, C. A. (2013) Effects of plant genotype and insect dispersal rate on the population dynamics of a forest pest. Ecology, 94(12), pp. 2792-2802. (doi: 10.1890/12-1708.1)

Gjini, E., Haydon, D.T. , Barry, J.D. and Cobbold, C.A. (2013) Linking the antigen archive structure to pathogen fitness in African trypanosomes. Proceedings of the Royal Society of London Series B: Biological Sciences, 280(1753), p. 20122129. (doi: 10.1098/rspb.2012.2129)

Leinster, T. and Cobbold, C. (2012) Measuring diversity: the importance of species similarity. Ecology, 93(3), pp. 477-489. (doi: 10.1890/10-2402.1)

Gjini, E., Haydon, D.T. , Barry, J.D. and Cobbold, C.A. (2012) The impact of mutation and gene conversion on the local diversification of antigen genes in African trypanosomes. Molecular Biology and Evolution, 29(11), pp. 3321-3331. (doi: 10.1093/molbev/mss166)

Higham, C.F., Morales, F., Cobbold, C.A. , Haydon, D.T. and Monckton, D.G. (2012) High levels of somatic DNA diversity at the myotonic dystrophy type 1 locus are driven by ultra-frequent expansion and contraction mutations. Human Molecular Genetics, 21(11), pp. 2450-2463. (doi: 10.1093/hmg/dds059)

Cobbold, C.A. and Powell, J.A. (2011) Evolution stabilises the synchronising dynamics of poikilotherm life cylces. Bulletin of Mathematical Biology, 73(5), pp. 1052-1081. (doi: 10.1007/s11538-010-9552-1)

Hackett-Jones, E., White, A. and Cobbold, C.A. (2011) The evolution of developmental timing in natural enemy systems. Journal of Theoretical Biology, 275(1), pp. 1-11. (doi: 10.1016/j.jtbi.2010.12.040)

Gjini, E., Haydon, D. , Barry, J. and Cobbold, C. (2010) Critical interplay between parasite differentiation, host immunity and antigenic variation in trypanosome infections. American Naturalist, 176(4), pp. 424-439. (doi: 10.1086/656276)

Cobbold, C.A., Roland, J. and Lewis, M.A. (2009) The impact of parasitoid emergence time on host-parasitoid population dynamics. Theoretical Population Biology, 75(2-3), pp. 201-215. (doi: 10.1016/j.tpb.2009.02.004)

Hackett-Jones, E., Cobbold, C.A. and White, A. (2009) Coexistence of multiple parasitoids on a single host due to differences in parasitoid phenology. Theoretical Ecology, 2(1), pp. 19-31. (doi: 10.1007/s12080-008-0025-1)

Cobbold, C.A., Lewis, M.A., Lutscher, F. and Roland, J. (2005) How parasitism affects critical patch-size in a host-parasitoid model: application to the forest tent caterpillar. Theoretical Population Biology, 67(2), pp. 109-125. (doi: 10.1016/j.tpb.2004.09.004)

Cobbold, C.A., Sherratt, J.A. and Maxwell, S.R.J. (2002) Lipoprotein oxidation and its significance for atherosclerosis: a mathematical approach. Bulletin of Mathematical Biology, 64(1), pp. 65-95. (doi: 10.1006/bulm.2001.0267)

Cobbold, C.A. (2001) The role of nitric oxide in the formation of keloid and hypertrophic lesions. Medical Hypotheses, 57(4), pp. 497-502. (doi: 10.1054/mehy.2001.1373)

Cobbold, C.A. and Sherratt, J. A. (2000) Mathematical modelling of nitric oxide activity in wound healing can explain keloid and hypertrophic scarring. Journal of Theoretical Biology, 204(2), pp. 257-288. (doi: 10.1006/jtbi.2000.2012)

Conference Proceedings

Higham, C., Wilcox, D., Haydon, D. , Cobbold, C. and Monckton, D. (2009) Modelling dynamic DNA in mytonic dystrophy. In: Sixth International Workshop on Computational Systems Biology, WCSB 2009, Aarhus, Denmark, 10-12 Jun 2009, pp. 63-66.

This list was generated on Tue Aug 3 20:29:41 2021 BST.

Supervision