Dr Manlio Tassieri

Reader (Biomedical Engineering)

email: Manlio.Tassieri@glasgow.ac.uk

R468, School of Engineering, Advanced Research Centre, Glasgow, G11 6EW

Biography

Manlio Tassieri is a Reader in Biomedical Engineering at the University of Glasgow. His research lies at the interface of rheology, microrheology, soft-matter physics and mechanobiology, with particular emphasis on the development of new experimental and analytical methods for measuring the mechanical and viscoelastic properties of complex materials and biological systems.

He graduated in Chemical Engineering from the University of Naples “Federico II” in 2000, where his early research focused on rheo-optical methods for the characterisation of polymer blends. After a period working as an engineering consultant, he moved to the University of Leeds in 2003 to undertake a PhD in Physics, investigating the microrheology of semiflexible biopolymers. He received his PhD in 2007 and subsequently worked as a postdoctoral researcher in the Polymer Science and Technology IRC at Leeds.

In 2008, he joined Biomedical Engineering at the University of Glasgow, initially investigating the application of optical tweezers to the mechanical characterisation of biological cells. In 2010, he was awarded a Royal Academy of Engineering/EPSRC Research Fellowship to develop microrheological and microfluidic approaches for probing biological systems at micro- and nanometre length scales. He subsequently established an independent research programme in rheology and microrheology and was appointed Reader in Biomedical Engineering in 2022.

His research has led to the development of the i-Rheo framework, a family of model-free analytical and experimental approaches for broadband rheological characterisation. These methods span conventional and microrheology, optical tweezers, atomic force microscopy, indentation, squeeze flow and time-resolved rheometry, and have been applied to systems ranging from polymers, hydrogels and colloidal materials to cells, multicellular spheroids and soft biological tissues. His current research also addresses the dynamics and mechanics of semiflexible polymer networks, mechanobiology, and the translation of rheological measurement science into biomedical and industrial applications.

Manlio is a Member-at-Large of the Executive Council of the European Society of Rheology (2026–2027), having previously served on its Executive Board. He is an elected Ordinary Member of the Institute of Physics Polymer Physics Group, Liquids and Complex Fluids Group, and Biological Physics Group committees. He is also an EPSRC Peer Review Full College Member, an Associate Member of the Institute of Non-Newtonian Fluid Mechanics, an Editorial Board Member of Scientific Reports, an Advisory Board Member of Physics of Fluids, and an Associate Editor for Frontiers in Bioengineering and Biotechnology – Biomaterials.

Research interests

Manlio’s research spans rheology, microrheology, soft-matter physics, statistical mechanics and mechanobiology, with a common interest in understanding how microscopic dynamics give rise to macroscopic mechanical behaviour and in developing new ways to extract that information from experiments.

A major strand of his work is the i-Rheo framework, a family of analytical and experimental approaches for broadband rheological measurements. These methods have been applied across a wide range of systems, including polymers, hydrogels, colloidal materials, living cells, multicellular spheroids and soft biological tissues.

His current research interests include:

Rheology and microrheology of complex materials: investigating the viscoelastic response of polymers, soft solids, hydrogels, biological materials and other complex fluids, with particular emphasis on broadband measurements and model-independent analysis.
Semiflexible polymers and polymer dynamics: studying the dynamics and mechanics of systems such as actin filaments, DNA-based structures and polymer networks, and the links between molecular-scale motion, confinement and bulk mechanical response.
Statistical mechanics of stochastic and dynamical systems: developing analytical relationships that connect fluctuations, memory, transport and time correlations, with applications to stochastic processes, deterministic dynamics and complex time-dependent systems.
Mechanobiology and biomedical materials: studying the mechanical properties of cells, multicellular spheroids, tissues and biomaterials, and how their rheological behaviour influences biological function and cellular response.
Biomedical signal analysis: developing physics-based and statistical approaches for the analysis of physiological signals, including electrocardiograms (ECGs), with the aim of identifying dynamical signatures associated with abnormalities and cardiovascular conditions.

More broadly, his research combines experimental physics, engineering, statistical mechanics and data analysis to develop new tools for probing the dynamics and mechanics of complex systems.

Publications

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Number of items: 81.

2026

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2026) The i-Rheo Framework: a unified approach to broadband rheology and microrheology of soft matter from molecular simulations to biomechanics. Micromachines, (Accepted for Publication)

Fernandez, Andrea Jannina, Skopalik, Simeon, Smart, Claire, Gibson, Graham M. ORCID: https://orcid.org/0000-0003-0051-8654, Noriega Escobar, María del Pilar and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2026) i-Rheo-Indent: broadband rheological characterisation of soft solids by macroscale indentation. Rheologica Acta, 65(10), pp. 835-848. (doi: 10.1007/s00397-026-01590-7) (PMID:42763463) (PMCID:PMC13588888)

Charalambides, M.N. et al. (2026) Recent progress and future opportunities in rheology: a review by the British Society of Rheology. Proceedings of the Royal Society A, 482(2346), 20251108. (doi: 10.1098/rspa.2025.1108)

Ramírez, Jorge and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2026) i-Rheo-Tempo: a model-free, quadrature-free reconstruction of the shear relaxation modulus from complex viscosity. Journal of Rheology, 70(5), pp. 1089-1104. (doi: 10.1122/8.0001232)

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2026) Memory and motion: a simple identity in stochastic transport. Transport Phenomena, 1(2), 20260047. (doi: 10.1515/tp-2026-0047)

Soapworks Limited (2026) Rheological measurement system. .

2025

Fernandez, Andrea Jannina, Gibson, Graham M. ORCID: https://orcid.org/0000-0003-0051-8654, Rył, Anna and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2025) Microrheology: from video microscopy to optical tweezers. Micromachines, 16(8), 918. (doi: 10.3390/mi16080918)

Mendonca, Tania, Urban, Roman, Lucken, Kellie, Coney, George, Kad, Neil M., Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Wright, Amanda J. and Booth, Daniel G. (2025) The mitotic chromosome periphery modulates chromosome mechanics. Nature Communications, 16, 6399. (doi: 10.1038/s41467-025-61755-5)

Masubuchi, Yuichi, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Ianniruberto, Giovanni and Marrucci, Giuseppe (2025) Persistence length and plateau modulus of semiflexible entangled polymers in primitive chain network simulations. Nihon Reoroji Gakkaishi, 53(3), pp. 119-125. (doi: 10.1678/rheology.53.119)

2024

Ramírez, Jorge, Gibson, Graham M. ORCID: https://orcid.org/0000-0003-0051-8654 and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2024) Optical Halo: a proof of concept for a new broadband microrheology tool. Micromachines, 15(7), 889. (doi: 10.3390/mi15070889) (PMID:39064399) (PMCID:PMC11278636)

Ferraro, Rosalia, Guido, Stefano, Caserta, Sergio and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2024) i-Rheo-optical assay: Measuring the viscoelastic properties of multicellular spheroids. Materials Today Bio, 26, 101066. (doi: 10.1016/j.mtbio.2024.101066) (PMID:38693994) (PMCID:PMC11061759)

Walker, Matthew ORCID: https://orcid.org/0000-0001-5119-9118, Pringle, Eonan William, Ciccone, Giuseppe, Oliver Cervello, Lluís, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Gourdon, Delphine and Cantini, Marco ORCID: https://orcid.org/0000-0003-0326-1508 (2024) Mind the viscous modulus: the mechanotransductive response to the viscous nature of isoelastic matrices regulates stem cell chondrogenesis. Advanced Healthcare Materials, 13(9), 2302571. (doi: 10.1002/adhm.202302571) (PMID:38014647)

Matheson, Andrew B., Mendonca, Tania, Smith, Matthew G., Sutcliffe, Ben, Fernandez, Andrea Jannina, Paterson, Lynn, Dalgarno, Paul A., Wright, Amanda J. and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2024) Fully angularly resolved 3D microrheology with optical tweezers. Rheologica Acta, 63, pp. 205-217. (doi: 10.1007/s00397-024-01435-1) (PMID:38440195) (PMCID:PMC10908627)

2023

Lyons, Ashley ORCID: https://orcid.org/0000-0002-6804-2106, Zickus, Vytautas ORCID: https://orcid.org/0000-0003-4042-2091, Alvarez-Mendoza, Raul, Triggiani, Danilo, Tamma, Vincenzo, Westerberg, Niclas ORCID: https://orcid.org/0000-0002-9876-5858, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Faccio, Daniele ORCID: https://orcid.org/0000-0001-8397-334X (2023) Fluorescence lifetime Hong-Ou-Mandel sensing. Nature Communications, 14, 8005. (doi: 10.1038/s41467-023-43868-x) (PMID:38049423) (PMCID:PMC10696080)

Smith, Matthew G., Gibson, Graham M. ORCID: https://orcid.org/0000-0003-0051-8654, Link, Andreas ORCID: https://orcid.org/0000-0002-1141-2831, Raghavan, Anand, Clarke, Andrew, Franke, Thomas and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2023) The role of elastic instability on the self-assembly of particle chains in simple shear flow. Physics of Fluids, 35(12), 122017. (doi: 10.1063/5.0182175)

Kazaz, Oguzhan, Ferraro, Rosalia, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Kumar, Shanmugam ORCID: https://orcid.org/0000-0002-3386-8012, Falcone, Gioia ORCID: https://orcid.org/0000-0001-8206-673X, Karimi, Nader ORCID: https://orcid.org/0000-0002-4559-6245 and Paul, Manosh C. ORCID: https://orcid.org/0000-0002-6510-456X (2023) Sensible heat thermal energy storage performance of mono and blended nanofluids in a free convective-radiation inclined system. Case Studies in Thermal Engineering, 51, 103562. (doi: 10.1016/j.csite.2023.103562)

Hardiman, William, Clark, Matt, Friel, Claire, Huett, Alan, Pérez-Cota, Fernando, Setchfield, Kerry, Wright, Amanda J. and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2023) Living cells as a biological analog of optical tweezers – a non-invasive microrheology approach. Acta Biomaterialia, 166, pp. 317-325. (doi: 10.1016/j.actbio.2023.04.039) (PMID:37137402)

Smith, Matthew G., Radford, Jack ORCID: https://orcid.org/0000-0003-4807-1628, Febrianto, Eky ORCID: https://orcid.org/0000-0001-8838-6240, Ramírez, Jorge, O'Mahony, Helen, Matheson, Andrew B., Gibson, Graham M. ORCID: https://orcid.org/0000-0003-0051-8654, Faccio, Daniele ORCID: https://orcid.org/0000-0001-8397-334X and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2023) Machine learning opens a doorway for microrheology with optical tweezers in living systems. AIP Advances, 13(7), 075315. (doi: 10.1063/5.0161014)

Mendonca, T. et al. (2023) OptoRheo: simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systems. Communications Biology, 6, 463. (doi: 10.1038/s42003-023-04780-8)

Geonzon, Lester C., Kobayashi, Motoyoshi, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Bacabac, Rommel G., Adachi, Yasuhisa and Matsukawa, Shingo (2023) Microrheological properties and local structure of ι-carrageenan gels probed by using optical tweezers. Food Hydrocolloids, 137, 108325. (doi: 10.1016/j.foodhyd.2022.108325)

Ferraro, Rosalia, Guido, Stefano, Caserta, Sergio and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2023) Compressional stress stiffening & softening of soft hydrogels - how to avoid artefacts in their rheological characterisation. Soft Matter, 19(11), pp. 2053-2057. (doi: 10.1039/D3SM00077J) (PMID:36866743)

Perris, Jack, Kumar, Charchit ORCID: https://orcid.org/0000-0002-6912-3506, Xu, Yang ORCID: https://orcid.org/0000-0002-7111-5134, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Kartal, Mehmet E., Gadegaard, Nikolaj ORCID: https://orcid.org/0000-0002-3396-846X and Mulvihill, Daniel M. ORCID: https://orcid.org/0000-0003-1693-0088 (2023) 3D printing and rapid replication of advanced numerically generated rough surface topographies in numerous polymers. Advanced Engineering Materials, 25(1), 2200832. (doi: 10.1002/adem.202200832)

2022

Laurati, Marco, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Espinosa, Gabriel, Oliveira, Mónica S. N. and Joseph, Pierre (2022) Editorial: exploring the mechanical properties of soft materials at multiple length scales. Frontiers in Physics, 10, 1111099. (doi: 10.3389/fphy.2022.1111099)

Ciccone, Giuseppe, Skopalik, Simeon, Smart, Claire, Gezgin, Senol, Ridland, David, Paul, Manosh C. ORCID: https://orcid.org/0000-0002-6510-456X, Escobar, María del Pilar Noriega and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2022) A rheological characterization of synthetic detergent formulations. Physics of Fluids, 34, 097109. (doi: 10.1063/5.0099145)

2021

Matheson, Andrew B., Mendonca, Tania, Gibson, Graham M. ORCID: https://orcid.org/0000-0003-0051-8654, Dalgarno, Paul A., Wright, Amanda J., Paterson, Lynn and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2021) Microrheology with an anisotropic optical trap. Frontiers in Physics, 9, 621512. (doi: 10.3389/fphy.2021.621512)

Matheson, Andrew B., Paterson, Lynn, Wright, Amanda J., Mendonca, Tania, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Dalgarno, Paul A. (2021) Optical tweezers with integrated multiplane microscopy (OpTIMuM): a new tool for 3D microrheology. Scientific Reports, 11, 5614. (doi: 10.1038/s41598-021-85013-y) (PMID:33692443) (PMCID:PMC7946888)

De Santis, M. M. et al. (2021) Extracellular matrix reinforced bioinks for 3D bioprinting human tissue. Advanced Materials, 33(3), 2005476. (doi: 10.1002/adma.202005476) (PMID:33300242)

Guadayol, Òscar, Mendonca, Tania, Segura-Noguera, Mariona, Wright, Amanda J., Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Humphries, Stuart (2021) Microrheology reveals microscale viscosity gradients in planktonic systems. Proceedings of the National Academy of Sciences of the United States of America, 118(1), e2011389118. (doi: 10.1073/pnas.2011389118)

Matheson, Andrew B., Paterson, Lynn, Wright, Amanda J., Mendonca, Tania, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Dalgarno, Paul A. (2021) Optical Tweezers with Integrated Multiplane Microscopy (OpTIMuM) – a new tool for 3D microrheology. Scientific Reports, 11, 5614. (doi: 10.1038/s41598-021-85013-y) (PMID:33692443) (PMCID:PMC7946888)

Smith, Matthew G., Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Gibson, Graham M. ORCID: https://orcid.org/0000-0003-0051-8654 (2021) i-RheoFT: Fourier transforming sampled functions without artefacts. Scientific Reports, 11, 24047.

2020

Ciccone, Giuseppe, Dobre, Oana ORCID: https://orcid.org/0000-0003-1968-5428, Gibson, Graham M. ORCID: https://orcid.org/0000-0003-0051-8654, Rey, Jose Manuel, Gonzalez-Garcia, Cristina, Vassalli, Massimo ORCID: https://orcid.org/0000-0002-3063-4376, Salmeron-Sanchez, Manuel ORCID: https://orcid.org/0000-0002-8112-2100 and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2020) What caging force cells feel in 3D hydrogels: a rheological perspective. Advanced Healthcare Materials, 9(17), 2000517. (doi: 10.1002/adhm.202000517) (PMID:32696605)

Orapiriyakul, W. et al. (2020) Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for 3D bone tissue engineering. ACS Nano, 14(8), pp. 10027-10044. (doi: 10.1021/acsnano.0c03130) (PMID:32658450) (PMCID:PMC7458485)

Rivas-Barbosa, Rodrigo, Escobedo-Sánchez, Manuel A., Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Laurati, Marco (2020) i-Rheo: determining the linear viscoelastic moduli of colloidal dispersions from step-stress measurements. Physical Chemistry Chemical Physics, 22, pp. 3839-3848. (doi: 10.1039/C9CP06191F)

Ashworth, J.C. et al. (2020) Peptide gels of fully-defined composition and mechanics for probing cell-cell and cell-matrix interactions in vitro. Matrix Biology, 85-86, pp. 15-33. (doi: 10.1016/j.matbio.2019.06.009) (PMID:31295578)

2019

Khalid, Muhammad Arslan ORCID: https://orcid.org/0000-0002-1797-590X, Ray, Anirudda, Cohen, Steve, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Demčenko, Andriejus ORCID: https://orcid.org/0000-0003-0881-3981, Tseng, Derek, Reboud, Julien ORCID: https://orcid.org/0000-0002-6879-8405, Ozcan, Aydogan and Cooper, Jonathan M. ORCID: https://orcid.org/0000-0002-2358-1050 (2019) Computational image analysis of guided acoustic waves enables rheological assessment of sub-nanoliter volumes. ACS Nano, 13(10), pp. 11062-11069. (doi: 10.1021/acsnano.9b03219) (PMID:31490647)

Moreno-Guerra, José A., Romero-Sánchez, Ivany C., Martinez-Borquez, Alejandro, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Stiakakis, Emmanuel and Laurati, Marco (2019) Model-free Rheo-AFM probes the viscoelasticity of tunable DNA soft colloids. Small, 15(42), 1904136. (doi: 10.1002/smll.201904136) (PMID:31460707)

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2019) Microrheology with optical tweezers: Peaks and troughs. Current Opinion in Colloid and Interface Science, 43, pp. 39-51. (doi: 10.1016/j.cocis.2019.02.006)

Khalid, Arslan ORCID: https://orcid.org/0000-0002-1797-590X, Ray, Aniruddah, Demčenko, Andriejus ORCID: https://orcid.org/0000-0003-0881-3981, Cohen, Steve, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Reboud, Julien ORCID: https://orcid.org/0000-0002-6879-8405, Ozcan, Aydogan and Cooper, Jonathan M. ORCID: https://orcid.org/0000-0002-2358-1050 (2019) Lens-free Microscopy Using Acoustically Actuated Nanolenses and its Applications. In: Imaging and Applied Optics 2019, Munich, Germany, 24-27 Jun 2019, CTu4C.6. ISBN 9781943580637 (doi: 10.1364/COSI.2019.CTu4C.6)

2018

Rizzi, Leandro G. and Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2018) Microrheology of biological specimens. In: Meyers, Robert A. (ed.) Encyclopedia of Analytical Chemistry. Wiley: Chichester. ISBN 9780471976707

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2018) Comment on "A symmetrical method to obtain shear moduli from microrheology" by Kengo Nishi, Maria L. Kilfoil, Christoph F. Schmidt, and F. C. MacKintosh, Soft Matter, 2018, 14, 3716. Soft Matter, 14(42), pp. 8666-8670. (doi: 10.1039/C8SM00806J) (PMID:30320864)

Chim, Ya Hua, Mason, Louise M., Rath, Nicola, Olson, Michael F. ORCID: https://orcid.org/0000-0003-3428-3507, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Yin, Huabing ORCID: https://orcid.org/0000-0001-7693-377X (2018) A one-step procedure to probe the viscoelastic properties of cells by Atomic Force Microscopy. Scientific Reports, 8, 14462. (doi: 10.1038/s41598-018-32704-8) (PMID:30262873) (PMCID:PMC6160452)

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Ramirez, Jorge, Karayiannis, Nikos Ch., Sukumaran, Sathish K. and Masubuchi, Yuichi (2018) i-Rheo GT: transforming from time to frequency domain without artifacts. Macromolecules, 51(14), pp. 5055-5068. (doi: 10.1021/acs.macromol.8b00447)

2017

Nazarzadeh, Elijah ORCID: https://orcid.org/0000-0002-1027-4924, Wilson, Rab ORCID: https://orcid.org/0000-0002-2070-6700, King, Xi, Reboud, Julien ORCID: https://orcid.org/0000-0002-6879-8405, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Cooper, Jonathan ORCID: https://orcid.org/0000-0002-2358-1050 (2017) Confinement of surface waves at the air-water interface to control aerosol size and dispersity. Physics of Fluids, 29(11), 112105. (doi: 10.1063/1.4993793)

Paterson, David J., Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Reboud, Julien ORCID: https://orcid.org/0000-0002-6879-8405, Wilson, Rab ORCID: https://orcid.org/0000-0002-2070-6700 and Cooper, Jonathan M. ORCID: https://orcid.org/0000-0002-2358-1050 (2017) Lipid topology and electrostatic interactions underpin lytic activity of linear cationic antimicrobial peptides in membranes. Proceedings of the National Academy of Sciences of the United States of America, 114(40), E8324-E8332. (doi: 10.1073/pnas.1704489114) (PMID:28931578)

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2017) Dynamics of semiflexible polymer solutions in the tightly entangled concentration regime. Macromolecules, 50(14), pp. 5611-5618. (doi: 10.1021/acs.macromol.7b01024)

Del Giudice, Francesco, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Oelschlaeger, Claude and Shen, Amy Q. (2017) When microrheology, bulk rheology, and microfluidics meet: broadband rheology of hydroxyethyl cellulose water solutions. Macromolecules, 50(7), pp. 2951-2963. (doi: 10.1021/acs.macromol.6b02727)

Tiller, Benjamin, Reboud, Julien ORCID: https://orcid.org/0000-0002-6879-8405, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Wilson, Rab ORCID: https://orcid.org/0000-0002-2070-6700 and Cooper, Jonathan M. ORCID: https://orcid.org/0000-0002-2358-1050 (2017) Frequency dependence of microflows upon acoustic interactions with fluids. Physics of Fluids, 29(12), 122008. (doi: 10.1063/1.4999308)

2016

Jimenez, M. ORCID: https://orcid.org/0000-0002-4631-0608, Khalid, M.A. ORCID: https://orcid.org/0000-0002-1797-590X, Wilson, R. ORCID: https://orcid.org/0000-0002-2070-6700, Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Reboud, J. ORCID: https://orcid.org/0000-0002-6879-8405 and Cooper, J.M. ORCID: https://orcid.org/0000-0002-2358-1050 (2016) Clotting Blood Using Surface Acoustic Waves. In: 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2016), Dublin, Ireland, 09-13 Oct 2016, pp. 1661-1662. ISBN 9781510834163

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Laurati, Marco, Curtis, Dan J., Auhl, Dietmar W., Coppola, Salvatore, Scalfati, Andrea, Hawkins, Karl, Williams, Phylip Rhodri and Cooper, Jonathan M. ORCID: https://orcid.org/0000-0002-2358-1050 (2016) i-Rheo: Measuring the materials' linear viscoelastic properties 'in a step'! Journal of Rheology, 60(4), pp. 649-660. (doi: 10.1122/1.4953443)

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2016) Introduction to linear rheology. In: Tassieri, Manlio (ed.) Microrheology with Optical Tweezers: Principles and Applications. CRC Press. ISBN 9789814669184

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2016) Microrheology with optical tweezers. In: Tassieri, Manlio (ed.) Microrheology with Optical Tweezers: Principles and Applications. CRC Press. ISBN 9789814669184

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2016) Microrheology with Optical Tweezers: Principles and Applications. CRC Press. ISBN 9789814669184

2015

Khalid, Muhammad Arslan ORCID: https://orcid.org/0000-0002-1797-590X, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Cooper, Jon ORCID: https://orcid.org/0000-0002-2358-1050 (2015) Contactless Viscosity Sensor Using Surface Acoustic Waves and Light Scattering. British Society of Rheology Mid-Winter Meeting 2015, Glasgow, UK, 14-15 Dec 2015.

Tassieri, M. et al. (2015) Microrheology with optical tweezers: measuring the relative viscosity of solutions 'at a glance'. Scientific Reports, 5, 8831. (doi: 10.1038/srep08831) (PMID:25743468) (PMCID:PMC4894396)

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2015) Linear microrheology with optical tweezers of living cells 'is not an option'! Soft Matter, 11, pp. 5792-5798. (doi: 10.1039/C5SM01133G) (PMID:26100967)

2014

Paterson, D. J., Reboud, J. ORCID: https://orcid.org/0000-0002-6879-8405, Wilson, R. ORCID: https://orcid.org/0000-0002-2070-6700, Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385 and Cooper, J. M. ORCID: https://orcid.org/0000-0002-2358-1050 (2014) Integrating microfluidic generation, handling and analysis of biomimetic giant unilamellar vesicles. Lab on a Chip, 14(11), p. 1806. (doi: 10.1039/C4LC00199K)

Lee, M.P., Gibson, G.M. ORCID: https://orcid.org/0000-0003-0051-8654, Phillips, D., Padgett, M.J. ORCID: https://orcid.org/0000-0001-6643-0618 and Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385 (2014) Dynamic stereo microscopy for studying particle sedimentation. Optics Express, 22(4), pp. 4671-4677. (doi: 10.1364/OE.22.004671)

Robertson, E.J. et al. (2014) Cryptococcus neoformans ex vivo capsule size is associated with intracranial pressure and host immune response in HIV-associated cryptococcal meningitis. Journal of Infectious Diseases, 209(1), pp. 74-82. (doi: 10.1093/infdis/jit435)

2013

Dholakia, K., Lee, M.P., Gibson, G. ORCID: https://orcid.org/0000-0003-0051-8654, Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Phillips, D., Bernet, S., Ritsh-Marte, M. and Padgett, M.J. ORCID: https://orcid.org/0000-0001-6643-0618 (2013) Spatial light modulation for improved microscope stereo vision and 3D tracking. In: SPIE Optics and Photonics 2013, San Diego, USA, 25 Aug - 29 Aug 2013, p. 881022. (doi: 10.1117/12.2027734)

Pommella, A., Preziosi, V., Caserta, S., Cooper, J.M. ORCID: https://orcid.org/0000-0002-2358-1050, Guido, S. and Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385 (2013) Using optical tweezers for the characterization of polyelectrolyte solutions with very low viscoelasticity. Langmuir, 29(29), pp. 9224-9230. (doi: 10.1021/la4015948)

Warren, R.L., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Li, X., Glidle, A., Paterson, D.J., Carlsson, A. and Cooper, J.M. ORCID: https://orcid.org/0000-0002-2358-1050 (2013) Rheology at the micro-scale: new tools for bio-analysis. In: Optical Methods for Inspection, Characterization and Imaging of Biomaterials, Munich, Germany, 13-16 May 2013, (doi: 10.1117/12.2025254)

Watts, Fiona, Tan, Lay Ean, Wilson, Clive G, Girkin, John M, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Wright, Amanda J (2013) Investigating the micro-rheology of the vitreous humor using an optically trapped local probe. Journal of Optics, 16(1), 015301. (doi: 10.1088/2040-8978/16/1/015301)

2012

Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Evans, R.M.L., Warren, R.L., Bailey, N.J. ORCID: https://orcid.org/0000-0002-9026-6560 and Cooper, J.M. ORCID: https://orcid.org/0000-0002-2358-1050 (2012) Microrheology with optical tweezers: data analysis. New Journal of Physics, 14(11), p. 115032. (doi: 10.1088/1367-2630/14/11/115032)

Lee, M.P., Curran, A., Gibson, G.M. ORCID: https://orcid.org/0000-0003-0051-8654, Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Heckenberg, N.R. and Padgett, M.J. ORCID: https://orcid.org/0000-0001-6643-0618 (2012) Optical shield: measuring viscosity of turbid fluids using optical tweezers. Optics Express, 20(11), pp. 12127-12132. (doi: 10.1364/OE.20.012127)

2011

Nayak, K., Read, D.J., McLeish, T.C.B., Hine, P.J. and Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385 (2011) A coarse-grained molecular model of strain-hardening for polymers in the marginally glassy state. Journal of Polymer Science Part B: Polymer Physics, 49(13), pp. 920-938. (doi: 10.1002/polb.22263)

Preece, D., Warren, R., Evans, R.M.L., Gibson, G.M. ORCID: https://orcid.org/0000-0003-0051-8654, Padgett, M.J. ORCID: https://orcid.org/0000-0001-6643-0618, Cooper, J. ORCID: https://orcid.org/0000-0002-2358-1050 and Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385 (2011) Optical tweezers: wideband microrheology. Journal of Optics, 13(4), 04402. (doi: 10.1088/2040-8978/13/4/044022)

Boyle, J.H., Berri, S., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Hope, I.A. and Cohen, N. (2011) Gait modulation in C. Elegans: it's not a choice, it's a reflex! Frontiers in Behavioral Neuroscience, 5, p. 10. (doi: 10.3389/fnbeh.2011.00010)

Dholakia, K., Watts, F., Tan, L.E., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, McAlinden, N., Wilson, C.G., Girkin, J.M., Wright, A.J. and Spalding, G.C. (2011) The viscoelastic properties of the vitreous humor measured using an optically trapped local probe. In: Optical Trapping and Optical Micromanipulation VIII, San Diego, CA, USA, 21-25 Aug 2011, 80970H-80970H. (doi: 10.1117/12.895192)

2010

Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Gibson, G. ORCID: https://orcid.org/0000-0003-0051-8654, Evans, R.M.L., Yao, A.M., Warren, R., Padgett, M.J. ORCID: https://orcid.org/0000-0001-6643-0618 and Cooper, J.M. ORCID: https://orcid.org/0000-0002-2358-1050 (2010) Measuring storage and loss moduli using optical tweezers: broadband microrheology. Physical Review E, 81(2), 026308. (doi: 10.1103/PhysRevE.81.026308)

Embery, J., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Hine, P. J. and Lord, T. D. (2010) An investigation into the constriction flow of a particle reinforced polystyrene melt using a combination of flow visualization and finite element simulations. Journal of Rheology, 54(5), pp. 1097-1117. (doi: 10.1122/1.3478307)

Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Waigh, T.A., Trinick, J., Aggeli, A. and Evans, R.M.L. (2010) Analysis of the linear viscoelasticity of polyelectrolytes by magnetic microrheometry—pulsed creep experiments and the one particle response. Journal of Rheology, 54(1), p. 117. (doi: 10.1122/1.3266946)

2009

Yao, Alison, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Padgett, Miles ORCID: https://orcid.org/0000-0001-6643-0618 and Cooper, Jonathan ORCID: https://orcid.org/0000-0002-2358-1050 (2009) Microrheology with optical tweezers. Lab on a Chip, 9(17), pp. 2568-2575. (doi: 10.1039/b907992k)

Berri, S., Boyle, J.H., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Hope, I.A. and Cohen, N. (2009) Forward locomotion of the nematode C. elegans is achieved through modulation of a single gait. HFSP Journal, 3(3), p. 186. (doi: 10.2976/1.3082260)

Evans, R.M.L., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Auhl, D. and Waigh, T.A. (2009) Direct conversion of rheological compliance measurements into storage and loss moduli. Physical Review E, 80(1), (doi: 10.1103/PhysRevE.80.012501)

2008

Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Evans, R., Barbu-Tudoran, L., Khaname, G., Trinick, J. and Waigh, T. (2008) Dynamics of semiflexible polymer solutions in the highly entangled regime. Physical Review Letters, 101(19), (doi: 10.1103/PhysRevLett.101.198301)

Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Evans, R.M.L., Barbu-Tudoran, L., Trinick, J. and Waigh, T.A. (2008) The self-assembly, elasticity, and dynamics of cardiac thin filaments^☆. Biophysical Journal, 94(6), pp. 2170-2178. (doi: 10.1529/biophysj.107.116087)

2005

Carrick, L., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Waigh, T.A., Aggeli, A., Boden, N., Bell, C., Fisher, J., Ingham, E. and Evans, R.M.L. (2005) The internal dynamic modes of charged self-assembled peptide fibrils. Langmuir, 21(9), pp. 3733-3737. (doi: 10.1021/la046802f) (PMID:15835929)

Simeone, M., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385, Sibillo, V. and Guido, S. (2005) Effect of sol–gel transition on shear-induced drop deformation in aqueous mixtures of gellan and κ-carrageenan. Journal of Colloid and Interface Science, 281(2), pp. 488-494. (doi: 10.1016/j.jcis.2004.08.095)

2003

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385, Grizzuti, Nino and Greco, Francesco (2003) Rheo-optical determination of the interfacial tension in a dispersed blend. Macromolecular Symposia, 198(1), pp. 53-68. (doi: 10.1002/masy.200350806)

2002

Simeone, M., Sibillo, V., Tassieri, M. ORCID: https://orcid.org/0000-0002-6807-0385 and Guido, S. (2002) Shear-induced clustering of gelling droplets in aqueous biphasic mixtures of gelatin and dextran. Journal of Rheology, 46(5), pp. 1263-1278. (doi: 10.1122/1.1501962)

2001

Wolf, Bettina, Frith, William J., Singleton, Scott, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Norton, Ian T. (2001) Shear behaviour of biopolymer suspensions with spheroidal and cylindrical particles. Rheologica Acta, 40(3), pp. 238-247. (doi: 10.1007/s003970000133)

This list was generated on Tue Oct 20 03:50:14 2026 BST.

Number of items: 81.

Articles

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2026) Memory and motion: a simple identity in stochastic transport. Transport Phenomena, 1(2), 20260047. (doi: 10.1515/tp-2026-0047)

Mendonca, T. et al. (2023) OptoRheo: simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systems. Communications Biology, 6, 463. (doi: 10.1038/s42003-023-04780-8)

De Santis, M. M. et al. (2021) Extracellular matrix reinforced bioinks for 3D bioprinting human tissue. Advanced Materials, 33(3), 2005476. (doi: 10.1002/adma.202005476) (PMID:33300242)

Matheson, Andrew B., Paterson, Lynn, Wright, Amanda J., Mendonca, Tania, Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 and Dalgarno, Paul A. (2021) Optical Tweezers with Integrated Multiplane Microscopy (OpTIMuM) – a new tool for 3D microrheology. Scientific Reports, 11, 5614. (doi: 10.1038/s41598-021-85013-y) (PMID:33692443) (PMCID:PMC7946888)

Books

Tassieri, Manlio ORCID: https://orcid.org/0000-0002-6807-0385 (2016) Microrheology with Optical Tweezers: Principles and Applications. CRC Press. ISBN 9789814669184

Book Sections

Conference or Workshop Item

Conference Proceedings

Patents

Soapworks Limited (2026) Rheological measurement system. .

This list was generated on Tue Oct 20 03:50:14 2026 BST.

Grants

£573,684.00 research grant awarded on February 2023 by EPSRC & NERC, in collaboration with Prof. Daniele Faccio and Prof. Stuart Humphries at the University of Lincoln. Project title: "Quantum-enabled Nano-scale Rheology Of The Microbial Seawater Environment" (EP/X035905/1 - EP/X035689/1).

£232,731.00 research grant awarded on June 2021 by Innovate UK, Knowledge Transfer Partnerships (KTP), in collaboration with Prof. Manosh Paul and Soapworks Ltd. KTP Application (12905).

£27,525.00 research grant awarded on January 2021 by EPSRC IAA & Glasgow Knowledge Exchange Fund, in collaboration with Prof. Manosh Paul and Soapworks Limited. Project title: "Panta Rhei: Syndet Characterisation and Process Modelling".

£11,000.00 International Exchanges 2020 grant awarded on January 2021 by The Royal Society/CNR, in collaboration with Dr M. Vassalli, Prof. D. Fioretto and Dr M. Mattarelli. Project title: "Novel tools for mechanobiology: from Atomic Force Microscopy to Brillouin spectroscopy" (IEC/R2/202232).

£12,995.00 research grant awarded on June 2020 by EPSRC IAA, in collaboration with Dr R.P. Middlemiss and Dr M. Vassalli. Project title: "Feel the Force: A calibration tool for cantilever-based force sensors".

1,080,000 JPY (~£7,440.00), awarded on the 15th of March 2019 by ICR, Kyoto University, in collaboration with Dr S. K. Sukumaran, Prof. Y. Masubuchi, Dr J. Ramirez, Prof. H. Watanabe and Dr Y. Matsumiya. Project title: "High Frequency Rheological and Dielectric Response of Polymeric Liquids".

£6750.00, awarded on the 18th of October 2018 by SRPe, in collaboration with academics and industries across UK and Europe. Title: "Artificial cells as distributed nanobots in Engineering and Healthcare".

£973,623.00, awarded on the 7th of March 2018 by the EPSRC, in collaboration with Prof. Amanda Wright et al. Project title: "Experiencing the micro-world - a cell's perspective" (EP/R035067/1 - EP/R035563/1 - EP/R035156/1).

£447,357.00, awarded on the 28th of November 2012 by the EPSRC, in collaboration with Professor Miles Padgett et al. Project title: "Upgrading the small scale equipment base for early career researchers in the engineering and physical sciences" (EP/K031732/1).

£40,000.00, awarded on the 11th of June 2012 by the University of Glasgow, School of Engineering, in collaboration with Dr Alasdair W. Clark and Dr Steven Neale. Project title: "Novel Optical Electrical Mechanical Sensory Platform".

£1,729.00, awarded on the 27th of April 2012 by the University of Glasgow, School of Eng. PI fund.

£763,325.00, awarded on the 1st of September 2010 by The Royal Academy of Engineering/EPSRC. Project title: "Rheology at the Microscale: New Tools for Bio-analysis" (10216/101).

Supervision

Manlio Tassieri is first supervisor to:

Mr Matthew Smith; Mrs Andrea Jannina Sanchez Fernandez; Mrs RosaliaFerraro; Mr Fernando Soto Bustamante; Mr Fraser Eadie.

Manlio Tassieri is second supervisor to:

Mr Charles Li; Mr George Bruce; MrGiuseppe Ciccone; MrShuai Bu.

A PhD position is available within the Biomedical Engineering Division. The aim of the project is to deliver new instruments and tools for measuring fundamental information on the nature of macromolecular interactions, in solution. For more information please contact Dr Manlio Tassieri (Manlio.Tassieri@glasgow.ac.uk).

Fernandez, Andrea Jannina
Be-Rheo: Beyond Conventional Rheometry in Biomedical Engineering

Teaching

Manlio has extensive experience in undergraduate and postgraduate teaching across Biomedical, Mechanical and General Engineering. He is Senior Adviser of Studies for Biomedical Engineering and has held this role since 2017, supporting students throughout their academic progression and contributing to the development and delivery of the Biomedical Engineering degree programmes.

He is currently responsible for major elements of Fluid Mechanics teaching within the James Watt School of Engineering, including ENG2085 Fluid Mechanics 2, delivered to more than 400 second-year Engineering students each year. His teaching also spans biomedical engineering, transport phenomena, rheology and the mechanical characterisation of biological and soft materials at undergraduate and postgraduate levels.

His teaching philosophy emphasises the connection between fundamental physical principles, real engineering applications and contemporary research. Examples drawn from areas such as aerodynamics, biomedical engineering, rheology and experimental measurement are used to demonstrate how theoretical concepts translate into engineering practice.

Manlio has also contributed to the University of Glasgow’s international teaching activities, including intensive delivery of Fluid Mechanics at the Singapore Institute of Technology. His teaching has consistently received strong student feedback.

Research datasets

Jump to: 2026 | 2024 | 2023 | 2022 | 2020 | 2019 | 2015

Number of items: 11.

2026

Tassieri, M. and Ramirez, J. (2026) i-Rheo-Tempo: Python Supplementary Files (README and Installation Configuration). [Data Collection]

Tassieri, M. and Ramírez, J. (2026) i-Rheo Tempo: Open-Access Analytical Tool for Broadband Viscoelastic Characterisation. [Data Collection]

2024

Haidar, Y. and Tassieri, M. (2024) i-Rheo-AFM. [Data Collection]

2023

Russell, B., Gonzalez Jimenez, M. , Tukachev, N., Hayes, L.-A., Chowdhury, T., Javornik, U., Mali, G., Tassieri, M. , Farnaby, J. , Senn, H. and Wynne, K. (2023) A second glass transition observed in single-component homogeneous liquids due to intramolecular vitrification. [Data Collection]

Lyons, A. , Zickus, V., Alvarez Mendoza, R., Triggiani, D., Tamma, V., Westerberg, N. , Tassieri, M. and Faccio, D. (2023) Fluorescence Lifetime Hong-Ou-Mandel Sensing. [Data Collection]

2022

Smith, M. and Tassieri, M. (2022) I-Rheo-AFM2. [Data Collection]

Smith, M. and Tassieri, M. (2022) I-Rheo. [Data Collection]

2020

Orapiriyakul, W., Tsimbouri, M. , Childs, P., Campsie, P., Wells, J., Fernandez-Yague, M. A., Burgess, K., Tanner, E., Tassieri, M. , Meek, D., Vassalli, M. , Biggs, M. J.P., Salmeron-Sanchez, M. , Oreffo, R. O. C., Reid, S. and Dalby, M. (2020) Nanovibrational Stimulation of Mesenchymal Stem Cells Induces Therapeutic Reactive Oxygen Species and Inflammation for Three- Dimensional Bone Tissue Engineering. [Data Collection]

2019

Tassieri, M. and MCGLONE, A. (2019) Time Displacement Series of a Silica Bead Optically Trapped in Water. [Data Collection] (Unpublished)

2015

Tassieri, M. , Evans, R.M.L., Auhl, D. and Waigh, T.A. (2015) Direct conversion of rheological compliance measurements into storage and loss moduli. [Data Collection]

Tassieri, M. , Evans, R.M.L., Warren, R., Bailey, N. and Cooper, J. (2015) Microrheology with optical tweezers. [Data Collection]

This list was generated on Tue Oct 20 10:16:41 2026 BST.

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James Watt School of Engineering

Dr Manlio Tassieri

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