Dr Chunxiao Hu

  • Lecturer: Biomedical Engineering (Biomedical Engineering)

telephone: 01413306458
email: Chunxiao.Hu@glasgow.ac.uk

Room 625, Rankine Building, Oakfield Avenue, School of Engineering, G12 8LT

Import to contacts

ORCID iDhttps://orcid.org/0000-0003-4031-1340

Biography

Dr Chunxiao Hu received a BSc in Automation (China, 2008), his MSc in Microsystem Technology (Southampton, 2009) and his PhD in Microfluidic devices for nematodes (Southampton, 2013). Following completion of his PhD, he worked as a Research Fellow at the University of Southampton, working on Nanowire/Nanoribbon ISFET for biosensing. From 2016, he moved to the University of Glasgow working as a Research Associate on CMOS based biosensors in the James Watt School of Engineering. He was promoted to Research Fellow in 2021, and now a Lecturer in Biomedical Engineering at the University of Glasgow. 

Research interests

Dr Chunxiao Hu's research focuses on developing miniaturised portable microsystem platforms by using advanced technologies such as microfluidics, nanofabrication, surface functionalization for biomedical applications. Current projects include Highly integrated chemical sensors (electrical and optical) for multiple detection of biomarkers for early cancer diagnostics; CMOS based ISFET for fast antimicrobial susceptibility testing; Wearable biosensor for continuous monitoring of stroke; Microfluidic device for neurodegenerative diseases; Microfluidic device for electrophysiological analysis of drug uptake in nematodes. Below are a few example research topics.

  • 1. CMOS-based sensor platform for personal diagostics.
  • 2. Thin film transistor based nanowire/nanoribbon sensor for point of care applications.
  • 3. Electrochemical measurement with 2-D material.
  • 4. Microfluidic device for neuron regeneration research.
  • 5. Multi-layer microfluidic device for electrophysiological analysis of C. elegans.

Publications

List by: Type | Date

Jump to: 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013
Number of items: 22.

2023

Hu, C. , Annese, V. F. , Barrett, M. P. and Cumming, D. R.S. (2023) Point-of-care platform for diagnosis of venous thrombosis by simultaneous detection of thrombin generation and D-dimer in human plasma. Analytical Chemistry, 95(2), pp. 1115-1122. (doi: 10.1021/acs.analchem.2c03819) (PMID:36544272) (PMCID:PMC9850404)

2022

Annese, V. F. and Hu, C. (2022) Integrating microfluidics and electronics in point-of-care diagnostics: current and future challenges. Micromachines, 13(11), 1923. (doi: 10.3390/mi13111923)

Hu, C. , Annese, V. F. , Giagkoulovits, C. , Barrett, M. P. and Cumming, D. R. S. (2022) Factor VIII companion diagnostic for haemophilia. Frontiers in Bioengineering and Biotechnology, 10, 1006600. (doi: 10.3389/fbioe.2022.1006600) (PMID:36277382) (PMCID:PMC9579283)

Annese, V. F. , Hu, C. , Barrett, M. P. , Jones, R. and Cumming, D. R. S. (2022) A CMOS-based multi-omics detection platform for simultaneous quantification of proteolytically active prostate specific antigen and glutamate in urine. IEEE Sensors Journal, 22(19), pp. 18870-18877. (doi: 10.1109/JSEN.2022.3198282)

Annese, V. F. , Giagkoulovits, C. , Hu, C. , Al-Rawhani, M. A., Grant, J. , Patil, S. and Cumming, D. (2022) Micromolar metabolite measurement in an electronically multiplexed format. IEEE Transactions on Biomedical Engineering, 69(9), pp. 2715-2722. (doi: 10.1109/TBME.2022.3147855) (PMID:35104208)

2021

Annese, V. F. et al. (2021) A monolithic single-chip point-of-care platform for metabolomic prostate cancer detection. Microsystems and Nanoengineering, 7, 21. (doi: 10.1038/s41378-021-00243-4) (PMID:34567735) (PMCID:PMC8433377)

2020

Hu, C. , Annese, V. , Velugotla, S. , Al-Rawhani, M. A., Cheah, B. C. , Grant, J. , Barrett, M. P. and Cumming, D. R.S. (2020) Disposable paper-on-CMOS platform for real-time simultaneous detection of metabolites. IEEE Transactions on Biomedical Engineering, 67(9), pp. 2417-2426. (doi: 10.1109/TBME.2019.2962239)

Al-Rawhani, M. A. et al. (2020) Multimodal integrated sensor platform for rapid biomarker detection. IEEE Transactions on Biomedical Engineering, 67(2), pp. 614-623. (doi: 10.1109/TBME.2019.2919192) (PMID:31226063)

2019

Annese, V. F. et al. (2019) The Multicorder: A Handheld Multimodal Metabolomics-on-CMOS Sensing Platform. In: 2019 IEEE 8th International Workshop on Advances in Sensors and Interfaces (IWASI), Otranto, Italy, 13-14 Jun 2019, pp. 130-135. ISBN 9781728105574 (doi: 10.1109/IWASI.2019.8791347)

2018

Hao, D., Hu, C. , Grant, J. , Glidle, A. and Cumming, D. R.S. (2018) Hybrid localized surface plasmon resonance and quartz crystal microbalance sensor for label free biosensing. Biosensors and Bioelectronics, 100, pp. 23-27. (doi: 10.1016/j.bios.2017.08.038) (PMID:28850824)

Hu, C. , Al-Rawhani, M. A., Cheah, B. C. , Velugotla, S. and Cumming, D. R.S. (2018) Hybrid dual mode sensor for simultaneous detection of two serum metabolites. IEEE Sensors Journal, 18(2), pp. 484-493. (doi: 10.1109/JSEN.2017.2774359)

2017

Hu, C. , Kalsi, S., Zeimpekis, I., Sun, K., Ashburn, P., Turner, C., Sutton, J. M. and Morgan, H. (2017) Ultra-fast electronic detection of antimicrobial resistance genes using isothermal amplification and Thin Film Transistor sensors. Biosensors and Bioelectronics, 96, pp. 281-287. (doi: 10.1016/j.bios.2017.05.016) (PMID:28505562)

Al-Rawhani, M. A. et al. (2017) A colorimetric CMOS-based platform for rapid total serum cholesterol quantification. IEEE Sensors Journal, 17(2), pp. 240-247. (doi: 10.1109/JSEN.2016.2629018)

2016

Sun, K., Zeimpekis, I., Hu, C. , Ditshego, N.M.J., Thomas, O., de Planque, M.R.R., Chong, H.M.H., Morgan, H. and Ashburn, P. (2016) Low-cost top-down zinc oxide nanowire sensors through a highly transferable ion beam etching for healthcare applications. Microelectronic Engineering, 153, pp. 96-100. (doi: 10.1016/j.mee.2016.02.016)

Hu, C. , Zeimpekis, I., Sun, K., Anderson, S., Ashburn, P. and Morgan, H. (2016) Low-cost nanoribbon sensors for protein analysis in human serum using a miniature bead-based enzyme-linked immunosorbent assay. Analytical Chemistry, 88(9), pp. 4872-4878. (doi: 10.1021/acs.analchem.6b00702) (PMID:27035411)

Kannan, P. K., Hu, C. , Morgan, H., Moshkalev, S. A. and Rout, C. S. (2016) Electrochemical sensing of bisphenol using a multilayer graphene nanobelt modified photolithography patterned platinum electrode. Nanotechnology, 27(37), p. 375504. (doi: 10.1088/0957-4484/27/37/375504) (PMID:27504686)

Kannan, P. K., Hu, C. , Morgan, H. and Rout, C. S. (2016) One-step electrodeposition of NiCo2S4 nanosheets on patterned platinum electrodes for non-enzymatic glucose sensing. Chemistry: An Asian Journal, 11(12), pp. 1837-1841. (doi: 10.1002/asia.201600362)

Sun, K., Zeimpekis, I., Hu, C. , Ditshego, N.M.J., Thomas, O., de Planque, M.R.R., Chong, H.M.H., Morgan, H. and Ashburn, P. (2016) Effect of subthreshold slope on the sensitivity of nanoribbon sensors. Nanotechnology, 27(28), p. 285501. (doi: 10.1088/0957-4484/27/28/285501) (PMID:27255984)

Zeimpekis, I., Sun, K., Hu, C. , Ditshego, N.M.J., Thomas, O., de Planque, M.R.R., Chong, H.M.H., Morgan, H. and Ashburn, P. (2016) Dual-gate polysilicon nanoribbon biosensors enable high sensitivity detection of proteins. Nanotechnology, 27(16), p. 165502. (doi: 10.1088/0957-4484/27/16/165502) (PMID:26954011)

2015

Zeimpekis, I., Sun, K., Hu, C. , Thomas, O., de Planque, M. R.R., Chong, H. M.H., Morgan, H. and Ashburn, P. (2015) Study of parasitic resistance effects in nanowire and nanoribbon biosensors. Nanoscale Research Letters, 10, 79. (doi: 10.1186/s11671-015-0794-6) (PMID:25852375) (PMCID:PMC4385057)

2014

Hu, C. , Kearn, J., Urwin, P., Lilley, C., O' Connor, V., Holden-Dye, L. and Morgan, H. (2014) StyletChip: a microfluidic device for recording host invasion behaviour and feeding of plant parasitic nematodes. Lab on a Chip, 14(14), pp. 2447-2455. (doi: 10.1039/C4LC00292J) (PMID:24839944)

2013

Hu, C. , Dillon, J., Kearn, J., Murray, C., O’Connor, V., Holden-Dye, L. and Morgan, H. (2013) NeuroChip: a microfluidic electrophysiological device for genetic and chemical biology screening of Caenorhabditis elegans adult and larvae. PLoS ONE, 8(5), e64297. (doi: 10.1371/journal.pone.0064297) (PMID:23717588) (PMCID:PMC3661448)

This list was generated on Fri Apr 12 06:49:17 2024 BST.
Number of items: 22.

Articles

Hu, C. , Annese, V. F. , Barrett, M. P. and Cumming, D. R.S. (2023) Point-of-care platform for diagnosis of venous thrombosis by simultaneous detection of thrombin generation and D-dimer in human plasma. Analytical Chemistry, 95(2), pp. 1115-1122. (doi: 10.1021/acs.analchem.2c03819) (PMID:36544272) (PMCID:PMC9850404)

Annese, V. F. and Hu, C. (2022) Integrating microfluidics and electronics in point-of-care diagnostics: current and future challenges. Micromachines, 13(11), 1923. (doi: 10.3390/mi13111923)

Hu, C. , Annese, V. F. , Giagkoulovits, C. , Barrett, M. P. and Cumming, D. R. S. (2022) Factor VIII companion diagnostic for haemophilia. Frontiers in Bioengineering and Biotechnology, 10, 1006600. (doi: 10.3389/fbioe.2022.1006600) (PMID:36277382) (PMCID:PMC9579283)

Annese, V. F. , Hu, C. , Barrett, M. P. , Jones, R. and Cumming, D. R. S. (2022) A CMOS-based multi-omics detection platform for simultaneous quantification of proteolytically active prostate specific antigen and glutamate in urine. IEEE Sensors Journal, 22(19), pp. 18870-18877. (doi: 10.1109/JSEN.2022.3198282)

Annese, V. F. , Giagkoulovits, C. , Hu, C. , Al-Rawhani, M. A., Grant, J. , Patil, S. and Cumming, D. (2022) Micromolar metabolite measurement in an electronically multiplexed format. IEEE Transactions on Biomedical Engineering, 69(9), pp. 2715-2722. (doi: 10.1109/TBME.2022.3147855) (PMID:35104208)

Annese, V. F. et al. (2021) A monolithic single-chip point-of-care platform for metabolomic prostate cancer detection. Microsystems and Nanoengineering, 7, 21. (doi: 10.1038/s41378-021-00243-4) (PMID:34567735) (PMCID:PMC8433377)

Hu, C. , Annese, V. , Velugotla, S. , Al-Rawhani, M. A., Cheah, B. C. , Grant, J. , Barrett, M. P. and Cumming, D. R.S. (2020) Disposable paper-on-CMOS platform for real-time simultaneous detection of metabolites. IEEE Transactions on Biomedical Engineering, 67(9), pp. 2417-2426. (doi: 10.1109/TBME.2019.2962239)

Al-Rawhani, M. A. et al. (2020) Multimodal integrated sensor platform for rapid biomarker detection. IEEE Transactions on Biomedical Engineering, 67(2), pp. 614-623. (doi: 10.1109/TBME.2019.2919192) (PMID:31226063)

Hao, D., Hu, C. , Grant, J. , Glidle, A. and Cumming, D. R.S. (2018) Hybrid localized surface plasmon resonance and quartz crystal microbalance sensor for label free biosensing. Biosensors and Bioelectronics, 100, pp. 23-27. (doi: 10.1016/j.bios.2017.08.038) (PMID:28850824)

Hu, C. , Al-Rawhani, M. A., Cheah, B. C. , Velugotla, S. and Cumming, D. R.S. (2018) Hybrid dual mode sensor for simultaneous detection of two serum metabolites. IEEE Sensors Journal, 18(2), pp. 484-493. (doi: 10.1109/JSEN.2017.2774359)

Hu, C. , Kalsi, S., Zeimpekis, I., Sun, K., Ashburn, P., Turner, C., Sutton, J. M. and Morgan, H. (2017) Ultra-fast electronic detection of antimicrobial resistance genes using isothermal amplification and Thin Film Transistor sensors. Biosensors and Bioelectronics, 96, pp. 281-287. (doi: 10.1016/j.bios.2017.05.016) (PMID:28505562)

Al-Rawhani, M. A. et al. (2017) A colorimetric CMOS-based platform for rapid total serum cholesterol quantification. IEEE Sensors Journal, 17(2), pp. 240-247. (doi: 10.1109/JSEN.2016.2629018)

Sun, K., Zeimpekis, I., Hu, C. , Ditshego, N.M.J., Thomas, O., de Planque, M.R.R., Chong, H.M.H., Morgan, H. and Ashburn, P. (2016) Low-cost top-down zinc oxide nanowire sensors through a highly transferable ion beam etching for healthcare applications. Microelectronic Engineering, 153, pp. 96-100. (doi: 10.1016/j.mee.2016.02.016)

Hu, C. , Zeimpekis, I., Sun, K., Anderson, S., Ashburn, P. and Morgan, H. (2016) Low-cost nanoribbon sensors for protein analysis in human serum using a miniature bead-based enzyme-linked immunosorbent assay. Analytical Chemistry, 88(9), pp. 4872-4878. (doi: 10.1021/acs.analchem.6b00702) (PMID:27035411)

Kannan, P. K., Hu, C. , Morgan, H., Moshkalev, S. A. and Rout, C. S. (2016) Electrochemical sensing of bisphenol using a multilayer graphene nanobelt modified photolithography patterned platinum electrode. Nanotechnology, 27(37), p. 375504. (doi: 10.1088/0957-4484/27/37/375504) (PMID:27504686)

Kannan, P. K., Hu, C. , Morgan, H. and Rout, C. S. (2016) One-step electrodeposition of NiCo2S4 nanosheets on patterned platinum electrodes for non-enzymatic glucose sensing. Chemistry: An Asian Journal, 11(12), pp. 1837-1841. (doi: 10.1002/asia.201600362)

Sun, K., Zeimpekis, I., Hu, C. , Ditshego, N.M.J., Thomas, O., de Planque, M.R.R., Chong, H.M.H., Morgan, H. and Ashburn, P. (2016) Effect of subthreshold slope on the sensitivity of nanoribbon sensors. Nanotechnology, 27(28), p. 285501. (doi: 10.1088/0957-4484/27/28/285501) (PMID:27255984)

Zeimpekis, I., Sun, K., Hu, C. , Ditshego, N.M.J., Thomas, O., de Planque, M.R.R., Chong, H.M.H., Morgan, H. and Ashburn, P. (2016) Dual-gate polysilicon nanoribbon biosensors enable high sensitivity detection of proteins. Nanotechnology, 27(16), p. 165502. (doi: 10.1088/0957-4484/27/16/165502) (PMID:26954011)

Zeimpekis, I., Sun, K., Hu, C. , Thomas, O., de Planque, M. R.R., Chong, H. M.H., Morgan, H. and Ashburn, P. (2015) Study of parasitic resistance effects in nanowire and nanoribbon biosensors. Nanoscale Research Letters, 10, 79. (doi: 10.1186/s11671-015-0794-6) (PMID:25852375) (PMCID:PMC4385057)

Hu, C. , Kearn, J., Urwin, P., Lilley, C., O' Connor, V., Holden-Dye, L. and Morgan, H. (2014) StyletChip: a microfluidic device for recording host invasion behaviour and feeding of plant parasitic nematodes. Lab on a Chip, 14(14), pp. 2447-2455. (doi: 10.1039/C4LC00292J) (PMID:24839944)

Hu, C. , Dillon, J., Kearn, J., Murray, C., O’Connor, V., Holden-Dye, L. and Morgan, H. (2013) NeuroChip: a microfluidic electrophysiological device for genetic and chemical biology screening of Caenorhabditis elegans adult and larvae. PLoS ONE, 8(5), e64297. (doi: 10.1371/journal.pone.0064297) (PMID:23717588) (PMCID:PMC3661448)

Conference Proceedings

Annese, V. F. et al. (2019) The Multicorder: A Handheld Multimodal Metabolomics-on-CMOS Sensing Platform. In: 2019 IEEE 8th International Workshop on Advances in Sensors and Interfaces (IWASI), Otranto, Italy, 13-14 Jun 2019, pp. 130-135. ISBN 9781728105574 (doi: 10.1109/IWASI.2019.8791347)

This list was generated on Fri Apr 12 06:49:17 2024 BST.

Grants

  • 1. EPSRC IAA funding was awarded in 2020 (PI: £40,970).

Supervision

Selected interested PhD projects include:

  • Advanced biosensing platform for rapid diagnostics of antimicrobial Resistance.
  • Highly sensitive sensing platform for early cancer diagnosis.
  • Low-cost portable companion diagnostic device for bleeding disorders.
  • Multi-layer microfluidic device for drug screening tests.
  • Microfluidic platforms with 3D structure for nerve injury and regeneration study.
  • A novel AI-driven Microfluidic Device for Analysis of Cell Viability.
  • Metal oxide nanoparticles-functionalized metal–organic framework (MOFs) for antibacterial applications.

Teaching

Lecturer in :

  • Biomolecular Processes in Biomedical Engineering ENG1071
  • Biosensors and Diagnostics 4 ENG4036

Helping Glasgow's participation to : 

  • SenUs competition since 2023

Research datasets