Number of items: 36.
2024
Shead, K. D., Huethorst, E. , Burton, F., Lang, N. , Myles, R. C. and Smith, G. L.
(2024)
Human induced pluripotent stem cell derived cardiomyocytes for pre-clinical cardiotoxicity screening.
JACC: CardioOncology,
(Accepted for Publication)
Freeman, M., Huethorst, E. , Boland, E., Dunne, M., Burton, F., Denning, C., Myles, R. and Smith, G.
(2024)
A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit.
American Journal of Physiology: Heart and Circulatory Physiology, 326(3),
H735--H751.
(doi: 10.1152/ajpheart.00657.2023)
(PMID:38180449)
2023
Simitev, R. D. , Al dawoud, A., Aziz, M. H.N., Myles, R. and Smith, G. L.
(2023)
Phenomenological analysis of simple ion channel block in large populations of uncoupled cardiomyocytes.
Mathematical Medicine and Biology, 40(2),
pp. 175-198.
(doi: 10.1093/imammb/dqad001)
(PMID:36689769)
Mooney, L., Jackson, C. E., Adamson, C., McConnachie, A. , Welsh, P. , Myles, R. C. , McMurray, J. J.V. , Jhund, P. S. , Petrie, M. C. and Lang, N. N.
(2023)
Adverse outcomes associated with interleukin-6 in patients recently hospitalized for heart failure with preserved ejection fraction.
Circulation: Heart Failure, 16(4),
e010051.
(doi: 10.1161/CIRCHEARTFAILURE.122.010051)
(PMID:36896709)
(PMCID:PMC10101136)
Alexander, C., Bishop, M. J., Gilchrist, R. J., Burton, F. L., Smith, G. L. and Myles, R. C.
(2023)
Initiation of ventricular arrhythmia in the acquired long QT syndrome.
Cardiovascular Research, 119(2),
pp. 465-476.
(doi: 10.1093/cvr/cvac103)
(PMID:35727943)
(PMCID:PMC10064840)
2022
Saxena, P., Myles, R. C. , Smith, G. L. and Workman, A. J.
(2022)
Adrenoceptor sub-type involvement in Ca2+ current stimulation by noradrenaline in human and rabbit atrial myocytes.
Pflügers Archiv European Journal of Physiology, 474(12),
pp. 1311-1321.
(doi: 10.1007/s00424-022-02746-z)
(PMID:36131146)
(PMCID:PMC9663393)
Lachaud, Q., Aziz, M. H. N., Burton, F. L., Macquaide, N. , Myles, R. C. , Simitev, R. D. and Smith, G. L.
(2022)
Electrophysiological heterogeneity in large populations of rabbit ventricular cardiomyocytes.
Cardiovascular Research, 118(15),
pp. 3112-3125.
(doi: 10.1093/cvr/cvab375)
(PMID:35020837)
(PMCID:PMC9732512)
2021
Sveberg Dietrichs, E., Myles, R. and Smith, G.
(2021)
Is hypothermia more neuroprotective than avoiding fever after cardiac arrest?
Cardiovascular Research, 117(12),
e159-e161.
(doi: 10.1093/cvr/cvab297)
(PMID:34718465)
(PMCID:PMC8562327)
Jabbour, R. J. et al.
(2021)
In vivo grafting of large engineered heart tissue patches for cardiac repair.
JCI Insight, 6(15),
e144068.
(doi: 10.1172/jci.insight.144068)
(PMID:34369384)
(PMCID:PMC8410032)
Wang, L., Myles, R. C. , Lee, I.-J., Bers, D. M. and Ripplinger, C. M.
(2021)
Role of reduced sarco-endoplasmic reticulum Ca2+-ATPase function on sarcoplasmic reticulum Ca2+ alternans in the intact rabbit heart.
Frontiers in Physiology, 12,
656516.
(doi: 10.3389/fphys.2021.656516)
(PMID:34045974)
(PMCID:PMC8144333)
Dobbin, S. J.H. , Petrie, M. C. , Myles, R. C. , Touyz, R. M. and Lang, N. N.
(2021)
Cardiotoxic effects of angiogenesis inhibitors.
Clinical Science, 135(1),
pp. 71-100.
(doi: 10.1042/CS20200305)
(PMID:33404052)
(PMCID:PMC7812690)
2020
Dietrichs, E. S., McGlynn, K., Allan, A., Connolly, A., Bishop, M., Burton, F., Kettlewell, S., Myles, R. , Tveita, T. and Smith, G. L.
(2020)
Moderate but not severe hypothermia causes pro-arrhythmic changes in cardiac electrophysiology.
Cardiovascular Research, 116(13),
pp. 2081-2090.
(doi: 10.1093/cvr/cvz309)
(PMID:32031595)
(PMCID:PMC7584464)
Dietrichs, E. S., Tveita, T., Myles, R. and Smith, G.
(2020)
A novel ECG-biomarker for cardiac arrest during hypothermia.
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 28,
27.
(doi: 10.1186/s13049-020-00721-0)
(PMID:32276599)
(PMCID:PMC7149849)
2019
Wang, L. et al.
(2019)
Different paths, same destination: divergent action potential responses produce conserved cardiac fight-or-flight response in mouse and rabbit hearts.
Journal of Physiology, 597(15),
pp. 3867-3883.
(doi: 10.1113/jp278016)
(PMID:31215643)
Kettlewell, S., Saxena, P., Dempster, J., Colman, M. A., Myles, R. C. , Smith, G. L. and Workman, A. J.
(2019)
Dynamic‐clamping human and rabbit atrial calcium current: narrowing ICaL window abolishes early afterdepolarisations.
Journal of Physiology, 597(14),
pp. 3619-3638.
(doi: 10.1113/JP277827)
(PMID:31093979)
(PMCID:PMC6767690)
2018
Connolly, A., Kelly, A., Campos, F. O., Myles, R. , Smith, G. and Bishop, M. J.
(2018)
Ventricular endocardial tissue geometry affects stimulus threshold and effective refractory period.
Biophysical Journal, 115(12),
pp. 2486-2498.
(doi: 10.1016/j.bpj.2018.11.003)
(PMID:30503533)
(PMCID:PMC6301915)
2017
Holman, R. R. et al.
(2017)
Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial.
Lancet Diabetes and Endocrinology, 5(11),
pp. 877-886.
(doi: 10.1016/S2213-8587(17)30309-1)
(PMID:28917545)
Murphy, S. R., Wang, L., Wang, Z., Domondon, P., Lang, D., Habecker, B. A., Myles, R. C. and Ripplinger, C. M.
(2017)
β-adrenergic inhibition prevents action potential and calcium handling changes during regional myocardial ischemia.
Frontiers in Physiology, 8,
630.
(doi: 10.3389/fphys.2017.00630)
(PMID:28894423)
(PMCID:PMC5581400)
2016
Gardner, R. T., Ripplinger, C. M., Myles, R. and Habecker, B. A.
(2016)
Molecular mechanisms of sympathetic remodeling and arrhythmias.
Circulation: Arrhythmia and Electrophysiology, 9(2),
e001359.
(doi: 10.1161/circep.115.001359)
(PMID:26810594)
(PMCID:PMC4730917)
2015
Myles, R. C. , Wang, L., Bers, D. M. and Ripplinger, C. M.
(2015)
Decreased inward rectifying K+current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart.
Journal of Physiology, 593(6),
pp. 1479-1493.
(doi: 10.1113/jphysiol.2014.279638)
(PMID:25772297)
2014
Wang, L., Myles, R. C. , De Jesus, N. M., Ohlendorf, A. K.P., Bers, D. M. and Ripplinger, C. M.
(2014)
Optical mapping of sarcoplasmic reticulum Ca2+ in the intact heart: ryanodine receptor refractoriness during alternans and fibrillation.
Circulation Research, 114(9),
pp. 1410-1421.
(doi: 10.1161/CIRCRESAHA.114.302505)
Jackson, C. E., Myles, R. C. and McMurray, J. J.V.
(2014)
Microvolt T-wave alternans testing in patients recently hospitalized with decompensated heart failure.
European Journal of Heart Failure, 16(1),
p. 113.
(doi: 10.1111/ejhf.45)
(PMID:24453101)
2013
Di Diego, J.M., Sicouri, S., Myles, R.C. , Burton, F., Smith, G.L. and Antzelevitch, C.
(2013)
Optical and electrical recordings from isolated coronary-perfused ventricular wedge preparations.
Journal of Molecular and Cellular Cardiology, 54,
pp. 53-64.
(doi: 10.1016/j.yjmcc.2012.10.017)
Jackson, C.E. et al.
(2013)
Feasibility/eligibility of T-wave alternans testing in patients with heart failure: should we rethink our current modus operandi?: reply.
European Journal of Heart Failure, 14(6),
pp. 676-677.
(doi: 10.1093/eurjhf/hfs050)
Kelly, A., Ghouri, I.A., Kemi, O.J. , Bishop, M.J., Bernus, O., Fenton, F.H., Myles, R.C. , Burton, F.L. and Smith, G.L.
(2013)
Subepicardial action potential characteristics are a function of depth and activation sequence in isolated rabbit hearts.
Circulation: Arrhythmia and Electrophysiology, 6(4),
pp. 809-817.
(doi: 10.1161/CIRCEP.113.000334)
2012
Jackson, C.E., Myles, R.C. , Cobbe, S.M., Petrie, M.C. and McMurray, J.J.V.
(2012)
Microvolt T-wave alternans testing has no role at present in guiding therapy for patients at high risk of ventricular arrhythmias.
Journal of the American College of Cardiology, 59(9),
p. 856.
(doi: 10.1016/j.jacc.2011.10.897)
Jackson, C.E. et al.
(2012)
Microvolt T-wave alternans (MTWA) testing in 'real world' heart failure (HF): a study of prevalence and incremental prognostic value.
Heart, 2012(98),
A12.
(doi: 10.1136/heartjnl-2012-301877b.17)
Jackson, C.E. et al.
(2012)
Microvolt T-wave alternans testing should be used to guide arrhythmic therapy in heart failure patients: reply.
European Journal of Heart Failure, 14(6),
p. 678.
(doi: 10.1093/eurjhf/hfs077)
Jackson, C.E. et al.
(2012)
Profile of microvolt T-wave alternans testing in 1003 patients hospitalized with heart failure.
European Journal of Heart Failure, 14(4),
pp. 377-386.
(doi: 10.1093/eurjhf/hfs010)
Myles, R.C. , Wang, L., Kang, C., Bers, D.M. and Ripplinger, C.M.
(2012)
Local β-adrenergic stimulation overcomes source-sink mismatch to generate focal arrhythmia.
Circulation Research, 110(11),
pp. 1454-1464.
(doi: 10.1161/CIRCRESAHA.111.262345)
Seegers, J. et al.
(2012)
Rationale, objectives, and design of the EUTrigTreat clinical study: a prospective observational study for arrhythmia risk stratification and assessment of interrelationships among repolarization markers and genotype.
Europace, 14(3),
pp. 416-422.
(doi: 10.1093/europace/eur352)
2011
Myles, R. , Burton, F.L., Cobbe, S. and Smith, G.L.
(2011)
Alternans of action potential duration and amplitude in rabbits with left ventricular dysfunction following myocardial infarction.
Journal of Molecular and Cellular Cardiology, 50(3),
pp. 510-512.
(doi: 10.1016/j.yjmcc.2010.11.019)
2010
Myles, R.C. , Bernus, O., Burton, F.L., Cobbe, S.M. and Smith, G.L.
(2010)
The effect of activation sequence on transmural patterns of repolarization and action potential duration in rabbit ventricular myocardium.
American Journal of Physiology: Heart and Circulatory Physiology, 289(8),
H1812-H1822.
(doi: 10.1152/ajpheart.00518.2010)
2009
Jackson, C.E., Dalzell, J.R., Bezlyak, V., Tsorlalis, I.K., Myles, R.C., Spooner, R., Ford, I., Petrie, M.C., Cobbe, S. and McMurray, J.J.
(2009)
Red cell distribution width has incremental prognostic value to B-type natriuretic peptide in acute heart failure.
European Journal of Heart Failure, 11(12),
pp. 1152-1154.
(doi: 10.1093/eurjhf/hfp157)
2008
Lang, N.N. , Myles, R.C., Burton, F.L., Hall, D.P., Chin, Y.Z., Boon, N.A. and Newby, D.E.
(2008)
The vascular effects of rotigaptide in vivo in man.
Biochemical Pharmacology, 76(10),
pp. 1194-1200.
(doi: 10.1016/j.bcp.2008.08.022)
Myles, R.C. , Burton, F.L., Cobbe, S.M. and Smith, G.L.
(2008)
The link between repolarisation alternans and ventricular arrhythmia: Does the cellular phenomenon extend to the clinical problem?
Journal of Molecular and Cellular Cardiology, 45(1),
pp. 1-10.
(doi: 10.1016/j.yjmcc.2008.03.024)
This list was generated on Fri Nov 8 09:10:24 2024 GMT.