Dr Colin Steele
- Clinical Senior Lecturer/ Honorary Consultant in Surgery (Clinical Research Garscube)
email:
Colin.Steele@glasgow.ac.uk
pronouns:
He/him/his
RI Cancer Sciences, Beatson Institute, Garscube Campus, Switchback Road, Bearsden, G61 1BD
Research interests
Research groups
Publications
2025
McMahon, Ross, O'Cathail, Sean ORCID: https://orcid.org/0000-0001-5574-9199, Steele, Colin
ORCID: https://orcid.org/0000-0001-8518-1223, Nair, Harikrishnan, Platt, Jonathan J., McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905 and Roxburgh, C.S.D.
ORCID: https://orcid.org/0000-0002-2649-6695
(2025)
Circulating markers of systemic inflammation, measured after completion of neoadjuvant therapy, associate with response in locally advanced rectal cancer.
Diseases of the Colon and Rectum,
(Accepted for Publication)
2024
Galbraith, N. J. et al. (2024) TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer. Translational Oncology, 48, 102064. (doi: 10.1016/j.tranon.2024.102064) (PMID:39068768)
Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)
Fetit, R. et al. (2024) Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer Research Communications, 4(2), pp. 588-606. (doi: 10.1158/2767-9764.CRC-23-0319) (PMID:38358352) (PMCID:PMC10903300)
2023
Galbraith, N. J. et al. (2023) Effect of differing flap reconstruction strategies in perineal closure following advanced pelvic oncological resection: a retrospective cohort study. International Journal of Surgery, 109(11), pp. 3375-3382. (doi: 10.1097/JS9.0000000000000617) (PMID:37678294) (PMCID:PMC10651229)
McMahon, Ross K., O'Cathail, Sean M. ORCID: https://orcid.org/0000-0001-5574-9199, Nair, Harikrishnan, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Platt, Jonathan J., Digby, Michael, McDonald, Alec C., Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905 and Roxburgh, Campbell S.D.
ORCID: https://orcid.org/0000-0002-2649-6695
(2023)
The neoadjuvant rectal score and a novel magnetic resonance imaging based neoadjuvant rectal score are stage independent predictors of long-term outcome in locally advanced rectal cancer.
Colorectal Disease, 25(9),
pp. 1783-1794.
(doi: 10.1111/codi.16667)
(PMID:37485654)
Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)
2022
Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)
Gould, Laura E., Pring, Edward T., Drami, Ioanna, Moorghen, Morgan, Naghibi, Mani, Jenkins, John T., Steele, Colin W. ORCID: https://orcid.org/0000-0001-8518-1223 and Roxburgh, Campbell S.D.
ORCID: https://orcid.org/0000-0002-2649-6695
(2022)
A systematic review of the pathological determinants of outcome following resection by pelvic exenteration of locally advanced and locally recurrent rectal cancer.
International Journal of Surgery, 104,
106738.
(doi: 10.1016/j.ijsu.2022.106738)
(PMID:35781038)
2021
Galbraith, Norman J. ORCID: https://orcid.org/0000-0002-6354-6946, Wood, Colin and Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223
(2021)
Targeting metastatic colorectal cancer with immune oncological therapies.
Cancers, 13(14),
3566.
(doi: 10.3390/cancers13143566)
(PMID:34298779)
(PMCID:PMC8307556)
McSorley, Stephen Thomas ORCID: https://orcid.org/0000-0002-5459-8445, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Anderson, John H. and McKinlay, Sonya
(2021)
Comment on 'Preoperative intravenous iron therapy and survival after colorectal cancer surgery: long term results from the IVICA randomised controlled trial'.
Colorectal Disease, 23(2),
pp. 555-556.
(doi: 10.1111/codi.15428)
(PMID:33159348)
2020
Golder, A.M. ORCID: https://orcid.org/0000-0002-0293-139X, Steele, C.W.
ORCID: https://orcid.org/0000-0001-8518-1223, Conn, D., Mackay, G.J., McMillan, D.C.
ORCID: https://orcid.org/0000-0003-4260-5334, Horgan, P.G.
ORCID: https://orcid.org/0000-0001-5557-7905, Roxburgh, C.S.
ORCID: https://orcid.org/0000-0002-2649-6695 and McSorley, S.T.
ORCID: https://orcid.org/0000-0002-5459-8445
(2020)
Authors' reply: Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided colonic and rectal resections.
BJS Open, 4(4),
pp. 730-731.
(doi: 10.1002/bjs5.50286)
(PMID:32297454)
(PMCID:PMC7397349)
McSorley, Stephen T. ORCID: https://orcid.org/0000-0002-5459-8445, Anderson, John H., Whittle, Thomas, Roxburgh, Campbell S.
ORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334 and Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223
(2020)
The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer.
Perioperative Medicine, 9,
17.
(doi: 10.1186/s13741-020-00146-4)
(PMID:32537137)
(PMCID:PMC7288411)
McSorley, Stephen T. ORCID: https://orcid.org/0000-0002-5459-8445, Tham, Alexander
ORCID: https://orcid.org/0000-0003-4601-1621, Dolan, Ross D.
ORCID: https://orcid.org/0000-0002-5272-5906, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Ramsingh, Jason, Roxburgh, Campbell
ORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905 and McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334
(2020)
Perioperative blood transfusion is associated with the postoperative systemic inflammatory response and poorer outcomes following surgery for colorectal cancer.
Annals of Surgical Oncology, 27,
pp. 833-843.
(doi: 10.1245/s10434-019-07984-7)
(PMID:31664621)
(PMCID:PMC7000540)
2019
Golder, A.M. ORCID: https://orcid.org/0000-0002-0293-139X, Steele, C.W.
ORCID: https://orcid.org/0000-0001-8518-1223, Conn, D., Mackay, G.J., McMillan, D.C.
ORCID: https://orcid.org/0000-0003-4260-5334, Horgan, P.G.
ORCID: https://orcid.org/0000-0001-5557-7905, Roxburgh, C.S.
ORCID: https://orcid.org/0000-0002-2649-6695 and McSorley, S.T.
ORCID: https://orcid.org/0000-0002-5459-8445
(2019)
Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short‐term outcomes following left‐sided colonic and rectal resections.
BJS Open, 3(6),
pp. 830-839.
(doi: 10.1002/bjs5.50224)
(PMID:31832590)
(PMCID:PMC6887908)
Jackstadt, R. et al. (2019) Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis. Cancer Cell, 36(3), 319-336.e7. (doi: 10.1016/j.ccell.2019.08.003) (PMID:31526760) (PMCID:PMC6853173)
Reader, C. S. et al. (2019) The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy. Journal of Pathology, 249(3), pp. 332-342. (doi: 10.1002/path.5320) (PMID:31259422) (PMCID:PMC6852434)
McSorley, Stephen T. ORCID: https://orcid.org/0000-0002-5459-8445, Tham, Alexander
ORCID: https://orcid.org/0000-0003-4601-1621, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Dolan, Ross D.
ORCID: https://orcid.org/0000-0002-5272-5906, Roxburgh, Campbell S.D.
ORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905 and McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334
(2019)
Quantitative data on red cell measures of iron status and their relation to the magnitude of the systemic inflammatory response and survival in patients with colorectal cancer.
European Journal of Surgical Oncology, 45(7),
pp. 1205-1211.
(doi: 10.1016/j.ejso.2019.02.027)
(PMID:30850153)
McSorley, Stephen ORCID: https://orcid.org/0000-0002-5459-8445, Johnstone, Mark, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Roxburgh, Campbell S.D.
ORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334 and Mansouri, David
ORCID: https://orcid.org/0000-0002-9157-6085
(2019)
Normocytic anaemia is associated with systemic inflammation and poorer survival in patients with colorectal cancer treated with curative intent.
International Journal of Colorectal Disease, 34(3),
pp. 401-408.
(doi: 10.1007/s00384-018-3211-7)
(PMID:30515556)
2018
McSorley, S.T. ORCID: https://orcid.org/0000-0002-5459-8445, Steele, C.W.
ORCID: https://orcid.org/0000-0001-8518-1223 and McMahon, A.J.
(2018)
Meta‐analysis of oral antibiotics, in combination with preoperative intravenous antibiotics and mechanical bowel preparation the day before surgery, compared with intravenous antibiotics and mechanical bowel preparation alone to reduce surgical‐site infections in elective colorectal surgery.
BJS Open, 2(4),
pp. 185-194.
(doi: 10.1002/bjs5.68)
(PMID:30079387)
(PMCID:PMC6069350)
2016
Steele, C. W. et al. (2016) CXCR2 inhibition profoundly suppresses metastases and augments immunotherapy in pancreatic ductal adenocarcinoma. Cancer Cell, 29(6), pp. 832-845. (doi: 10.1016/j.ccell.2016.04.014) (PMID:27265504) (PMCID:PMC4912354)
2015
Palani Velu, Lavanniya K., Steele, Colin W. ORCID: https://orcid.org/0000-0001-8518-1223, Dickson, Euan, Carter, C. Ross, McKay, Colin J., Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334 and Jamieson, Nigel B.
ORCID: https://orcid.org/0000-0002-9552-4725
(2015)
RE:nab-paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial.
Journal of the National Cancer Institute, 107(9),
djv204.
(doi: 10.1093/jnci/djv204)
(PMID:26251329)
Steele, C. et al. (2015) CXCR2 inhibition suppresses acute and chronic pancreatic inflammation. Journal of Pathology, 237(1), pp. 85-97. (doi: 10.1002/path.4555) (PMID:25950520)
Miller, B. W. et al. (2015) Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy. EMBO Molecular Medicine, 7, pp. 1063-1076. (doi: 10.15252/emmm.201404827) (PMID:26077591) (PMCID:PMC4551344)
Articles
McMahon, Ross, O'Cathail, Sean ORCID: https://orcid.org/0000-0001-5574-9199, Steele, Colin
ORCID: https://orcid.org/0000-0001-8518-1223, Nair, Harikrishnan, Platt, Jonathan J., McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905 and Roxburgh, C.S.D.
ORCID: https://orcid.org/0000-0002-2649-6695
(2025)
Circulating markers of systemic inflammation, measured after completion of neoadjuvant therapy, associate with response in locally advanced rectal cancer.
Diseases of the Colon and Rectum,
(Accepted for Publication)
Galbraith, N. J. et al. (2024) TAK1 expression is associated with increased PD-L1 and decreased cancer-specific survival in microsatellite-stable colorectal cancer. Translational Oncology, 48, 102064. (doi: 10.1016/j.tranon.2024.102064) (PMID:39068768)
Pennel, K. A.F. et al. (2024) JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors. Journal of Experimental and Clinical Cancer Research, 43, 64. (doi: 10.1186/s13046-024-02958-4)
Fetit, R. et al. (2024) Characterising neutrophil subtypes in cancer using scRNA sequencing demonstrates the importance of IL-1β/CXCR2 axis in generation of metastasis specific neutrophils. Cancer Research Communications, 4(2), pp. 588-606. (doi: 10.1158/2767-9764.CRC-23-0319) (PMID:38358352) (PMCID:PMC10903300)
Galbraith, N. J. et al. (2023) Effect of differing flap reconstruction strategies in perineal closure following advanced pelvic oncological resection: a retrospective cohort study. International Journal of Surgery, 109(11), pp. 3375-3382. (doi: 10.1097/JS9.0000000000000617) (PMID:37678294) (PMCID:PMC10651229)
McMahon, Ross K., O'Cathail, Sean M. ORCID: https://orcid.org/0000-0001-5574-9199, Nair, Harikrishnan, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Platt, Jonathan J., Digby, Michael, McDonald, Alec C., Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905 and Roxburgh, Campbell S.D.
ORCID: https://orcid.org/0000-0002-2649-6695
(2023)
The neoadjuvant rectal score and a novel magnetic resonance imaging based neoadjuvant rectal score are stage independent predictors of long-term outcome in locally advanced rectal cancer.
Colorectal Disease, 25(9),
pp. 1783-1794.
(doi: 10.1111/codi.16667)
(PMID:37485654)
Wood, C. S. et al. (2023) Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases. Cancer Research, 83(8), pp. 1329-1344. (doi: 10.1158/0008-5472.CAN-22-2794) (PMID:37057593) (PMCID:PMC10102851)
Pennel, K. A. F. et al. (2022) CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer. Journal of Pathology: Clinical Research, 8(6), pp. 509-520. (doi: 10.1002/cjp2.290) (PMID:35879507) (PMCID:PMC9535100)
Gould, Laura E., Pring, Edward T., Drami, Ioanna, Moorghen, Morgan, Naghibi, Mani, Jenkins, John T., Steele, Colin W. ORCID: https://orcid.org/0000-0001-8518-1223 and Roxburgh, Campbell S.D.
ORCID: https://orcid.org/0000-0002-2649-6695
(2022)
A systematic review of the pathological determinants of outcome following resection by pelvic exenteration of locally advanced and locally recurrent rectal cancer.
International Journal of Surgery, 104,
106738.
(doi: 10.1016/j.ijsu.2022.106738)
(PMID:35781038)
Galbraith, Norman J. ORCID: https://orcid.org/0000-0002-6354-6946, Wood, Colin and Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223
(2021)
Targeting metastatic colorectal cancer with immune oncological therapies.
Cancers, 13(14),
3566.
(doi: 10.3390/cancers13143566)
(PMID:34298779)
(PMCID:PMC8307556)
McSorley, Stephen Thomas ORCID: https://orcid.org/0000-0002-5459-8445, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Anderson, John H. and McKinlay, Sonya
(2021)
Comment on 'Preoperative intravenous iron therapy and survival after colorectal cancer surgery: long term results from the IVICA randomised controlled trial'.
Colorectal Disease, 23(2),
pp. 555-556.
(doi: 10.1111/codi.15428)
(PMID:33159348)
Golder, A.M. ORCID: https://orcid.org/0000-0002-0293-139X, Steele, C.W.
ORCID: https://orcid.org/0000-0001-8518-1223, Conn, D., Mackay, G.J., McMillan, D.C.
ORCID: https://orcid.org/0000-0003-4260-5334, Horgan, P.G.
ORCID: https://orcid.org/0000-0001-5557-7905, Roxburgh, C.S.
ORCID: https://orcid.org/0000-0002-2649-6695 and McSorley, S.T.
ORCID: https://orcid.org/0000-0002-5459-8445
(2020)
Authors' reply: Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short-term outcomes following left-sided colonic and rectal resections.
BJS Open, 4(4),
pp. 730-731.
(doi: 10.1002/bjs5.50286)
(PMID:32297454)
(PMCID:PMC7397349)
McSorley, Stephen T. ORCID: https://orcid.org/0000-0002-5459-8445, Anderson, John H., Whittle, Thomas, Roxburgh, Campbell S.
ORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334 and Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223
(2020)
The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer.
Perioperative Medicine, 9,
17.
(doi: 10.1186/s13741-020-00146-4)
(PMID:32537137)
(PMCID:PMC7288411)
McSorley, Stephen T. ORCID: https://orcid.org/0000-0002-5459-8445, Tham, Alexander
ORCID: https://orcid.org/0000-0003-4601-1621, Dolan, Ross D.
ORCID: https://orcid.org/0000-0002-5272-5906, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Ramsingh, Jason, Roxburgh, Campbell
ORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905 and McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334
(2020)
Perioperative blood transfusion is associated with the postoperative systemic inflammatory response and poorer outcomes following surgery for colorectal cancer.
Annals of Surgical Oncology, 27,
pp. 833-843.
(doi: 10.1245/s10434-019-07984-7)
(PMID:31664621)
(PMCID:PMC7000540)
Golder, A.M. ORCID: https://orcid.org/0000-0002-0293-139X, Steele, C.W.
ORCID: https://orcid.org/0000-0001-8518-1223, Conn, D., Mackay, G.J., McMillan, D.C.
ORCID: https://orcid.org/0000-0003-4260-5334, Horgan, P.G.
ORCID: https://orcid.org/0000-0001-5557-7905, Roxburgh, C.S.
ORCID: https://orcid.org/0000-0002-2649-6695 and McSorley, S.T.
ORCID: https://orcid.org/0000-0002-5459-8445
(2019)
Effect of preoperative oral antibiotics in combination with mechanical bowel preparation on inflammatory response and short‐term outcomes following left‐sided colonic and rectal resections.
BJS Open, 3(6),
pp. 830-839.
(doi: 10.1002/bjs5.50224)
(PMID:31832590)
(PMCID:PMC6887908)
Jackstadt, R. et al. (2019) Epithelial NOTCH signaling rewires the tumor microenvironment of colorectal cancer to drive poor-prognosis subtypes and metastasis. Cancer Cell, 36(3), 319-336.e7. (doi: 10.1016/j.ccell.2019.08.003) (PMID:31526760) (PMCID:PMC6853173)
Reader, C. S. et al. (2019) The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy. Journal of Pathology, 249(3), pp. 332-342. (doi: 10.1002/path.5320) (PMID:31259422) (PMCID:PMC6852434)
McSorley, Stephen T. ORCID: https://orcid.org/0000-0002-5459-8445, Tham, Alexander
ORCID: https://orcid.org/0000-0003-4601-1621, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Dolan, Ross D.
ORCID: https://orcid.org/0000-0002-5272-5906, Roxburgh, Campbell S.D.
ORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905 and McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334
(2019)
Quantitative data on red cell measures of iron status and their relation to the magnitude of the systemic inflammatory response and survival in patients with colorectal cancer.
European Journal of Surgical Oncology, 45(7),
pp. 1205-1211.
(doi: 10.1016/j.ejso.2019.02.027)
(PMID:30850153)
McSorley, Stephen ORCID: https://orcid.org/0000-0002-5459-8445, Johnstone, Mark, Steele, Colin W.
ORCID: https://orcid.org/0000-0001-8518-1223, Roxburgh, Campbell S.D.
ORCID: https://orcid.org/0000-0002-2649-6695, Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334 and Mansouri, David
ORCID: https://orcid.org/0000-0002-9157-6085
(2019)
Normocytic anaemia is associated with systemic inflammation and poorer survival in patients with colorectal cancer treated with curative intent.
International Journal of Colorectal Disease, 34(3),
pp. 401-408.
(doi: 10.1007/s00384-018-3211-7)
(PMID:30515556)
McSorley, S.T. ORCID: https://orcid.org/0000-0002-5459-8445, Steele, C.W.
ORCID: https://orcid.org/0000-0001-8518-1223 and McMahon, A.J.
(2018)
Meta‐analysis of oral antibiotics, in combination with preoperative intravenous antibiotics and mechanical bowel preparation the day before surgery, compared with intravenous antibiotics and mechanical bowel preparation alone to reduce surgical‐site infections in elective colorectal surgery.
BJS Open, 2(4),
pp. 185-194.
(doi: 10.1002/bjs5.68)
(PMID:30079387)
(PMCID:PMC6069350)
Steele, C. W. et al. (2016) CXCR2 inhibition profoundly suppresses metastases and augments immunotherapy in pancreatic ductal adenocarcinoma. Cancer Cell, 29(6), pp. 832-845. (doi: 10.1016/j.ccell.2016.04.014) (PMID:27265504) (PMCID:PMC4912354)
Palani Velu, Lavanniya K., Steele, Colin W. ORCID: https://orcid.org/0000-0001-8518-1223, Dickson, Euan, Carter, C. Ross, McKay, Colin J., Horgan, Paul G.
ORCID: https://orcid.org/0000-0001-5557-7905, McMillan, Donald C.
ORCID: https://orcid.org/0000-0003-4260-5334 and Jamieson, Nigel B.
ORCID: https://orcid.org/0000-0002-9552-4725
(2015)
RE:nab-paclitaxel plus gemcitabine for metastatic pancreatic cancer: long-term survival from a phase III trial.
Journal of the National Cancer Institute, 107(9),
djv204.
(doi: 10.1093/jnci/djv204)
(PMID:26251329)
Steele, C. et al. (2015) CXCR2 inhibition suppresses acute and chronic pancreatic inflammation. Journal of Pathology, 237(1), pp. 85-97. (doi: 10.1002/path.4555) (PMID:25950520)
Miller, B. W. et al. (2015) Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy. EMBO Molecular Medicine, 7, pp. 1063-1076. (doi: 10.15252/emmm.201404827) (PMID:26077591) (PMCID:PMC4551344)
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- An investigation into colorectal cancer in Scotland
Beatson Cancer Charity
2024 - 2025
- The role of TGF-Beta dysregulation and its relationship with tumour microenvironment factors in the development and progression of locally recurrent rectal cancers.
Royal College of Physicians and Surgeons of Glasgow
2024 - 2027
- IL6/JAK/STAT3 pathway in colorectal cancer
Office of the Chief Scientific Adviser
2023 - 2025
- Investigating the role of dietary constitution in radiotherapy responses in rectal cancer
Cancer Research UK
2023 - 2023
- Defining pro-tumourigenic neutrophil phenotypes and tumour-neutrophil interactions to identify targets for therapy in metastatic colorectal cancer
UK Research and Innovation
2022 - 2026
- Identification of novel tumour markers to aid prediction of high risk rectal cancers for local recurrence
NHS Greater Glasgow and Clyde Endowment Funds
2022 - 2023
- Combining Radiation with JAK inhibitors as a novel therapeutic strategy
Cancer Research UK
2022 - 2022
- Secondary prevention of colorectal liver metastasis via manipultion of the gut-liver axis
Tenovus Scotland
2021 - 2022
- Are CXCR2 positive cells important in generating an immunosuppressive metastatic niche for colorectal metastatic disease in the liver?
Cancer Research UK
2018 - 2020
- Characterising CXCR2 expressing neutrophils in colorectal liver metastases.
Academy of Medical Sciences
2018 - 2020
- Characterising the role of CXCR2 signalling in colorectal cancer metastasis
Chief Scientist Office
2017 - 2020