Number of items: 33.
2023
Edwards, S. C. et al.
(2023)
PD-1 and TIM-3 differentially regulate subsets of mouse IL-17A–producing γδ T cells.
Journal of Experimental Medicine, 220(2),
e20211431.
(doi: 10.1084/jem.20211431)
(PMID:36480166)
(PMCID:PMC9732671)
2022
O’Sullivan, E. D. et al.
(2022)
Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis.
JCI Insight, 7(22),
e154124.
(doi: 10.1172/jci.insight.154124)
Kapeni, C. et al.
(2022)
p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion.
Blood, 140(5),
pp. 464-477.
(doi: 10.1182/blood.2021014853)
(PMID:35653588)
Robertson, N. A. et al.
(2022)
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.
Nature Medicine, 28(7),
pp. 1439-1446.
(doi: 10.1038/s41591-022-01883-3)
(PMID:35788175)
(PMCID:PMC9307482)
Kay, E. J. et al.
(2022)
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix.
Nature Metabolism, 4(6),
pp. 693-710.
(doi: 10.1038/s42255-022-00582-0)
(PMID:35760868)
(PMCID:PMC9236907)
Tomimatsu, K. et al.
(2022)
Locus-specific induction of gene expression from heterochromatin loci during cellular senescence.
Nature Aging, 2,
pp. 31-45.
(doi: 10.1038/s43587-021-00147-y)
2021
Flanagan, D. J. et al.
(2021)
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer.
Nature, 594,
pp. 430-435.
(doi: 10.1038/s41586-021-03525-z)
(PMID:34079124)
Hsieh, Y.-C., Kirschner, K. and Copland, M.
(2021)
Improving outcomes in chronic myeloid leukemia through harnessing the immunological landscape.
Leukemia, 35(5),
pp. 1229-1242.
(doi: 10.1038/s41375-021-01238-w)
(PMID:33833387)
(PMCID:PMC8102187)
Mooney, L., Goodyear, C. S. , Chandra, T., Kirschner, K. , Copland, M. , Petrie, M. C. and Lang, N. N.
(2021)
Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure.
Clinical Science, 135(7),
pp. 991-1007.
(doi: 10.1042/CS20200306)
(PMID:33861346)
(PMCID:PMC8055963)
Rattanavirotkul, N., Kirschner, K. and Chandra, T.
(2021)
Induction and transmission of oncogene-induced senescence.
Cellular and Molecular Life Sciences, 78(3),
pp. 843-852.
(doi: 10.1007/s00018-020-03638-0)
(PMID:32936311)
(PMCID:PMC7897614)
Latif, A.-L. et al.
(2021)
BRD4-mediated repression of p53 is a target for combination therapy in AML.
Nature Communications, 12(1),
241.
(doi: 10.1038/s41467-020-20378-8)
(PMID:33431824)
(PMCID:PMC7801601)
2020
Crosse, E. I. et al.
(2020)
Multi-layered spatial transcriptomics identify secretory factors promoting human hematopoietic stem cell development.
Cell Stem Cell, 27(5),
822-839.e8.
(doi: 10.1016/j.stem.2020.08.004)
(PMID:32946788)
(PMCID:PMC7671940)
Alivernini, S. et al.
(2020)
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis.
Nature Medicine, 26(8),
pp. 1295-1306.
(doi: 10.1038/s41591-020-0939-8)
(PMID:32601335)
Terradas-Terradas, M. , Robertson, N. A., Chandra, T. and Kirschner, K.
(2020)
Clonality in haematopoietic stem cell ageing.
Mechanisms of Ageing and Development, 189,
111279.
(doi: 10.1016/j.mad.2020.111279)
(PMID:32526214)
(PMCID:PMC7347006)
Kirschner, K. , Rattanavirotkul, N., Quince, M. F. and Chandra, T.
(2020)
Functional heterogeneity in senescence.
Biochemical Society Transactions, 48(3),
pp. 765-773.
(doi: 10.1042/BST20190109)
(PMID:32369550)
(PMCID:PMC7329341)
2019
Burt, R. et al.
(2019)
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukaemia cells from oxidative stress.
Blood, 134(17),
pp. 1415-1429.
(doi: 10.1182/blood.2019001398)
(PMID:31501154)
(PMCID:PMC6856969)
Robertson, N. A., Hillary, R. F., McCartney, D. L., Terradas-Terradas, M. , Higham, J., Sproul, D., Deary, I. J., Kirschner, K. , Marioni, R. E. and Chandra, T.
(2019)
Age-related clonal haemopoiesis is associated with increased epigenetic age.
Current Biology, 29(16),
R786-R787.
(doi: 10.1016/j.cub.2019.07.011)
(PMID:31430471)
Teo, Y. V. et al.
(2019)
Notch signaling mediates secondary senescence.
Cell Reports, 27(4),
997-1007.e5.
(doi: 10.1016/j.celrep.2019.03.104)
(PMID:31018144)
(PMCID:PMC6486482)
2018
Baran-Gale, J., Chandra, T. and Kirschner, K.
(2018)
Experimental design for single-cell RNA sequencing.
Briefings in Functional Genomics, 17(4),
pp. 233-239.
(doi: 10.1093/bfgp/elx035)
(PMID:29126257)
(PMCID:PMC6063265)
Kirschner, K. , Krueger, F., Green, A. R. and Chandra, T.
(2018)
Multiplexing for oxidative bisulfite sequencing (oxBS-seq).
In: Tost, J. (ed.)
DNA Methylation Protocols.
Series: Methods in molecular biology, 1708 (1708).
Humana Press: New York, pp. 665-678.
ISBN 9781493974795
(doi: 10.1007/978-1-4939-7481-8_34)
2017
Kirschner, K. et al.
(2017)
Proliferation drives aging-related functional
decline in a subpopulation of the hematopoietic
stem cell compartment.
Cell Reports, 19(8),
pp. 1503-1511.
(doi: 10.1016/j.celrep.2017.04.074)
(PMID:28538171)
(PMCID:PMC5457484)
Kiselev, V. Y. et al.
(2017)
SC3: consensus clustering of single cell RNA-seq data.
Nature Methods, 14(5),
pp. 483-486.
(doi: 10.1038/nmeth.4236)
(PMID:28346451)
2016
Chandra, T. and Kirschner, K.
(2016)
Chromosome organisation during ageing and senescence.
Current Opinion in Cell Biology, 40,
pp. 161-167.
(doi: 10.1016/j.ceb.2016.03.020)
(PMID:27101466)
Park, H. J., Li, J., Hannah, R., Biddie, S., Leal‐Cervantes, A. I., Kirschner, K. , Flores Santa Cruz, D., Sexl, V., Göttgens, B. and Green, A. R.
(2016)
Cytokine‐induced megakaryocytic differentiation is regulated by genome‐wide loss of a uSTAT transcriptional program.
EMBO Journal, 35(6),
pp. 580-594.
(doi: 10.15252/embj.201592383)
(PMID:26702099)
(PMCID:PMC4801948)
2015
Kirschner, K. et al.
(2015)
Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.
PLoS Genetics, 11(3),
e1005053.
(doi: 10.1371/journal.pgen.1005053)
(PMID:25790137)
(PMCID:PMC4366240)
Chandra, T., Ewels, P. A., Schoenfelder, S., Furlan-Magaril, M., Wingett, S. W., Kirschner, K. , Thuret, J.-Y., Andrews, S., Fraser, P. and Reik, W.
(2015)
Global reorganization of the nuclear landscape in senescent cells.
Cell Reports, 10(4),
pp. 471-483.
(doi: 10.1016/j.celrep.2014.12.055)
(PMID:25640177)
(PMCID:PMC4542308)
2013
Kent, D. G. et al.
(2013)
Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion.
PLoS Biology, 11(6),
e1001576.
(doi: 10.1371/journal.pbio.1001576)
(PMID:23750118)
(PMCID:PMC3672217)
Ward, M. C. et al.
(2013)
Latent regulatory potential of human-specific repetitive elements.
Molecular Cell, 49(2),
pp. 262-272.
(doi: 10.1016/j.molcel.2012.11.013)
(PMID:23246434)
(PMCID:PMC3560060)
2012
Chandra, T. et al.
(2012)
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.
Molecular Cell, 47(2),
pp. 203-214.
(doi: 10.1016/j.molcel.2012.06.010)
(PMID:22795131)
(PMCID:PMC3701408)
2010
Kirschner, K. and Melton, D. W.
(2010)
Multiple roles of the ERCC1-XPF endonuclease in DNA repair and resistance to anticancer drugs.
Anticancer Research, 30(9),
pp. 3223-3232.
(PMID:20944091)
2009
Young, A. R.J. et al.
(2009)
Autophagy mediates the mitotic senescence transition.
Genes and Development, 23(7),
pp. 798-803.
(doi: 10.1101/gad.519709)
(PMID:19279323)
(PMCID:PMC2666340)
2007
Kirschner, K. , Singh, R., Prost, S. and Melton, D. W.
(2007)
Characterisation of Ercc1 deficiency in the liver and in conditional Ercc1-deficient primary hepatocytes in vitro.
DNA Repair, 6(3),
pp. 304-316.
(doi: 10.1016/j.dnarep.2006.10.020)
(PMID:17126084)
2003
Gunnarsson, C., Ahnström, M., Kirschner, K. , Olsson, B., Nordenskjöld, B., Rutqvist, L. E., Skoog, L. and Stål, O.
(2003)
Amplification of HSD17B1 and ERBB2 in primary breast cancer.
Oncogene, 22(1),
pp. 34-40.
(doi: 10.1038/sj.onc.1206078)
(PMID:12527905)
This list was generated on Sat Jan 28 13:12:20 2023 GMT.