Schools

Omar, R., Lee, M. A.W., Gonzalez-Trueba, L., Thomson, C. R., Hansen, U., Lianos, S., Hazarika, S., El Abdallah, O., Ammar, M. A., Cassels, J., Michie, A. M., Bulleid, N. J., Malfait, F., Van Agtmael, T. (2025) The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome. Cell Death Discovery, 11, (doi: 10.1038/s41420-025-02476-y)

Huang, D., Dearlove, E. (2025) Insights into non-proteinaceous ubiquitination. Biochemical Society Transactions,

Samarakoon, Y., Yelland, T., Garcia-Gonzalez, E., Justo-Junior, A. d. S., Mahmood, M., Manoharan, A., Patterson, S., Serafin, V., Gammage, P. A., Marmiroli, S., Halsey, C., Ismail, S., Roberts, E. W. (2025) UNC119 regulates T-cell receptor signalling in primary T cells and T acute lymphocytic leukaemia. Life Science Alliance, 8, (doi: 10.26508/lsa.202403066)

Pearson, L.-A., Petit, A.-P., Mendoza-Martinez, C., Bellany, F., Lin, D., Niven, S., Swift, R., Eadsforth, T., Fyfe, P. K., Paul, M., Postis, V., Hu, X., Cowling, V. H., Gray, D. W. (2025) Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach. Biochemical Journal, (doi: 10.1042/bcj20240608)

Morgan, D. C., McDougall, L., Knuhtsen, A., Buetow, L., Steven, C. F., Shepperson, O., Huang, D. T., Hulme, A. N., Jamieson, A. G. (2025) Raman active diyne-Girder conformationally constrained p53 stapled peptides bind to MDM2 for visualisation without fluorophores. RSC Chemical Biology, (doi: 10.1039/D4CB00288A)

Estcourt, L. J. et al. (2025) Tranexamic acid versus placebo to prevent bleeding in patients with haematological malignancies and severe thrombocytopenia (TREATT): a randomised, double-blind, parallel, phase 3 superiority trial. Lancet Haematology, 12, pp. e14-e22. (doi: 10.1016/S2352-3026(24)00317-X)

Apps, J., Halsey, C., Pritchard Jones, K., Atun, R., Shanmugavadivel, D., Oliver, K., Vedhara, K., Liu, J., Ball-Gamble, A., Ranasinghe, N., Polanco, A., Adamski, J., Green, A., Walker, D. A. (2024) A review calling for research directed at early detection of childhood cancers: the clinical, scientific, and economic arguments for population screening and surveillance. EJC Paediatric Oncology, 4, (doi: 10.1016/j.ejcped.2024.100191)

Laing, A., Elmarghany, A., Alghaith, A. A., Gouma, A., Stevens, T., Winton, A., Cassels, J., Clarke, C. J., Schwab, C., Harrison, C. J., Gibson, B., Keeshan, K. (2024) Paediatric bone marrow mesenchymal stem cells support acute myeloid leukaemia cell survival and enhance chemoresistance via contact-independent mechanism. British Journal of Haematology, (doi: 10.1111/bjh.19884)

Vosbein, P., Vergara, P. P., Huang, D. T., Thomson, A. R. (2024) An engineered ubiquitin binding coiled coil peptide. Chemical Science, 15, pp. 15776-15782. (doi: 10.1039/d4sc04204b)

Xavier, V., Martinelli, S., Corbyn, R., Pennie, R., Rakovic, K., Powley, I. R., Officer-Jones, L., Ruscica, V., Galloway, A., Carlin, L. M., Cowling, V. H., Le Quesne, J., Martinou, J.-C., MacVicar, T. (2024) Mitochondrial double-stranded RNA homeostasis depends on cell-cycle progression. Life Science Alliance, 7, (doi: 10.26508/lsa.202402764)

Copland, M. (2024) Triplet therapy for advanced BCR::ABL1 positive myeloid leukaemias. Lancet Haematology, 11, pp. e807-e808. (doi: 10.1016/S2352-3026(24)00282-5)

Bohlen, J. et al. (2024) Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation. Journal of Clinical Investigation, 134, (doi: 10.1172/JCI181604)

Dearlove, E. L., Chatrin, C., Buetow, L., Ahmed, S. F., Schmidt, T., Bushell, M., Smith, B. O., Huang, D. T. (2024) DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids. eLife, 13, (doi: 10.7554/elife.98070)

Anastasopoulou, S., Swann, G., Andres-Jensen, L., Attarbaschi, A., Barzilai-Birenboim, S., Erdelyi, D. J., Escherich, G., Hamadeh, L., Harila, A., Lopez-Lopez, E., McGowan, S., Möricke, A., Putti, C., Sagi, J. C., Schmiegelow, K., Ullrich, N. J., van der Sluis, I. M., ul-Ain Wahid, Q., Winick, N., Sramkova, L., Zalcberg, Y., Zapotocka, E., Bhojwani, D., Halsey, C. (2024) Severe steroid-related neuropsychiatric symptoms during paediatric acute lymphoblastic leukaemia therapy—An observational Ponte di Legno Toxicity Working Group Study. British Journal of Haematology, 205, pp. 1450-1459. (doi: 10.1111/bjh.19610)

Vosbein, P., Paredes Vergara, P., Huang, D. T., Thomson, D. (2024) AlphaFold ensemble competition screens enable peptide binder design with single-residue sensitivity. ACS Chemical Biology, (doi: 10.1021/acschembio.4c00418)

Innes, A. I. et al. (2024) Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy. Leukemia, 38, pp. 2443-2455. (doi: 10.1038/s41375-024-02411-7)

Patterson, S. D., Massett, M. E., Huang, X., Jørgensen, H. G., Michie, A. M. (2024) The MYC–NFATC2 axis maintains the cell cycle and mitochondrial function in acute myeloid leukaemia cells. Molecular Oncology, 18, pp. 2234-2254. (doi: 10.1002/1878-0261.13630)

Lukoszek, R., Inesta-Vaquera, F., Brett, N. J.M., Liang, S., Hepburn, L. A., Hughes, D. J., Pirillo, C., Roberts, E. W., Cowling, V. H. (2024) CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection. Cell Reports, 43, (doi: 10.1016/j.celrep.2024.114405)

Donnelly, H., Ross, E., Xiao, Y., Hermantara, R., Taqi, A., Doherty-Boyd, W. S., Cassels, J., Tsimbouri, P. M., Dunne, K. M., Hay, J., Cheng, A., Meek, R.M. D., Jain, N., West, C., Wheadon, H., Michie, A. M., Peault, B., West, A. G., Salmeron-Sanchez, M., Dalby, M. J. (2024) Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells. Nature Communications, 15, (doi: 10.1038/s41467-024-50054-0)

Busch, C., Nyamondo, K., Wheadon, H. (2024) Complexities of modelling the bone marrow microenvironment to facilitate haematopoietic research. Experimental Hematology, 135, (doi: 10.1016/j.exphem.2024.104233)

Ramirez-Guzman, L. A., Huang, W., Cole, J. J., Jorgensen, H. G. (2024) GAS2 upregulation is a targetable vulnerability in chronic myeloid leukaemia. International Journal of Translational Medicine, 4, pp. 354-368. (doi: 10.3390/ijtm4020023)

Khalaf, A., de Beauchamp, L., Kalkman, E., Rattigan, K., Himonas, E., Jones, J., James, D., Shokry, E. S. A., Scott, M. T., Dunn, K., Tardito, S., Copland, M., Sumpton, D., Shanks, E., Helgason, V. (2024) Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia. Science Translational Medicine, 16, (doi: 10.1126/scitranslmed.adi5336)

Wiesheu, R. et al. (2024) IL-27 maintains cytotoxic Ly6C+ T cells that arise from immature precursors. EMBO Journal, (doi: 10.1038/s44318-024-00133-1)

Mardilovich, K., Naylor, G., Julian, L., Phinichkusolchit, N., Keeshan, K., Blyth, K., Olson, M. F. (2024) Caspase-resistant ROCK1 expression prolongs survival of Eµ-Myc B cell lymphoma mice. Disease Models and Mechanisms, 17, (doi: 10.1242/dmm.050631)

Borland, G., Wilkie, S. E., Thomson, J., Wang, Z., Tullett, J. M.A., Alic, N., Selman, C. (2024) Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan. Aging Cell, 23, (doi: 10.1111/acel.14141)

Zarou, M. M., Rattigan, K. M., Sarnello, D., Shokry, E., Dawson, A., Ianniciello, A., Dunn, K., Copland, M., Sumpton, D., Vazquez, A., Helgason, V. (2024) Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1-mediated purine sensing. Nature Communications, 15, (doi: 10.1038/s41467-024-46114-0)

Copland, M., Ariti, C., Thomas, I. F., Upton, L., Sydenham, M., Mehta, P., Islam, S., Kjeldsen, L., Burnett, A. K., Hills, R. K., Russell, N., Dennis, M. (2024) A randomised evaluation of low-dose cytosine arabinoside plus lenalidomide versus single-agent low-dose cytosine arabinoside in older patients with acute myeloid leukaemia: Results from the LI-1 trial. British Journal of Haematology, 204, (doi: 10.1111/bjh.19220)

Vringer, E., Heilig, R., Riley, J. S., Black, A., Cloix, C., Skalka, G., Montes-Gómez, A. E., Aguado, A., Lilla, S., Walczak, H., Gyrd-Hansen, M., Murphy, D. J., Huang, D. T., Zanivan, S., Tait, S. W.G. (2024) Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response. EMBO Journal, 43, pp. 904-930. (doi: 10.1038/s44318-024-00044-1)

Dawson, A. et al. (2024) Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche. Nature Communications, 15, (doi: 10.1038/s41467-024-45471-0)

Scott, M. T., Liu, W., Mitchell, R., Clarke, C. J., Kinstrie, R., Warren, F., Almasoudi, H., Stevens, T., Dunn, K., Pritchard, J., Drotar, M. E., Michie, A. M., Jorgensen, H. G., Higgins, B., Copland, M., Vetrie, D. (2024) Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease. Nature Communications, 15, (doi: 10.1038/s41467-024-44771-9)

Rattigan, K. M. (2024) Mini review of metabolism in leukaemia: from complexity to the clinic. Frontiers in Hematology, 2, (doi: 10.3389/frhem.2023.1353994)

Nyamondo, K., Wheadon, H. (2024) Microenvironment alterations through time leading to myeloid malignancies. British Journal of Pharmacology, 181, pp. 283-294. (doi: 10.1111/bph.15924)

Knop, K., Gomez-Moreira, C., Galloway, A., Ditsova, D., Cowling, V. H. (2024) RAM is upregulated during T cell activation and is required for RNA cap formation and gene expression. Discovery Immunology, 3, (doi: 10.1093/discim/kyad021)

Malik, N., Hay, J., Almuhanna, H. N.B., Dunn, K. M., Lees, J., Cassels, J., Li, J., Nakagawa, R., Sansom, O. J., Michie, A. M. (2023) mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia. Leukemia, 37, pp. 2414-2425. (doi: 10.1038/s41375-023-02043-3)

Busch, C., Mulholland, T., Zagnoni, M., Dalby, M., Berry, C., Wheadon, H. (2023) Overcoming BCR::ABL1 dependent and independent survival mechanisms in chronic myeloid leukaemia using a multi-kinase targeting approach. Cell Communication and Signaling, 21, (doi: 10.1186/s12964-023-01363-2)

Zarou, M. M., Dawson, A., Prasad, B., Bittencourt-Silvestre, J., Zerbst, D., Rodriguez Blanco, G., Scott, M., Dunn, K., Krishnan, V., Copland, M., Vetrie, D., Bhatia, R., Coffelt, S., Ong, S. T., Wheadon, H., Zanivan, S., Kirschner, K., Helgason, G. V. (2023) Leukaemia Exposure Alters the Transcriptional Profile and Function of Macrophages in the Bone Marrow Niche. (doi: 10.1182/blood-2023-181630)

Rattigan, K. M., Zarou, M. M., Brabcova, Z., Prasad, B., Zerbst, D., Sarnello, D., Kalkman, E. R., Ianniciello, A., Scott, M. T., Dunn, K., Shokry, E., Sumpton, D., Copland, M., Tardito, S., Vande Voorde, J., Mussai, F., Cheng, P., Helgason, G. V. (2023) Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells. EMBO Reports, 24, (doi: 10.15252/embr.202256279)

Nikolatou, K., Sandilands, E., Román-Fernández, A., Cumming, E. M., Freckmann, E., Lilla, S., Buetow, L., McGarry, L., Neilson, M., Shaw, R., Strachan, D., Miller, C., Huang, D. T., Mcneish, I. A., Norman, J. C., Zanivan, S., Bryant, D. M. (2023) PTEN deficiency exposes a requirement for an ARF GTPase module for integrin-dependent invasion in ovarian cancer. EMBO Journal, 42, (doi: 10.15252/embj.2023113987)

Rattigan, K. M., Brabcova, Z., Sarnello, D., Zarou, M. M., Roy, K., Kwan, R., de Beauchamp, L., Dawson, A., Ianniciello, A., Khalaf, A., Kalkman, E. R., Scott, M. T., Dunn, K., Sumpton, D., Michie, A. M., Copland, M., Tardito, S., Gottlieb, E., Helgason, G. V. (2023) Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells. Nature Communications, 14, (doi: 10.1038/s41467-023-40222-z)

Darici, S., Jørgensen, H. G., Huang, X., Serafin, V., Antolini, L., Barozzi, P., Luppi, M., Forghieri, F., Marmiroli, S., Zavatti, M. (2023) Improved efficacy of quizartinib in combination therapy with PI3K inhibition in primary FLT3-ITD AML cells. Advances in Biological Regulation, 89, (doi: 10.1016/j.jbior.2023.100974)

Wilkie, S. E., Marcu, D. E., Carter, R. N., Morton, N. M., Gonzalo, S., Selman, C. (2023) Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome. Aging, 15, pp. 5266-5278. (doi: 10.18632/aging.204835)

Liang, S., Almohammed, R., Cowling, V. H. (2023) The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation. Biochemical Society Transactions, 51, pp. 1131-1141. (doi: 10.1042/BST20221154)

Yang, F., Nourse, C., Helgason, G. V., Kirschner, K. (2023) Unraveling heterogeneity in the aging hematopoietic stem cell compartment: an insight from single-cell approaches. HemaSphere, 7, (doi: 10.1097/hs9.0000000000000895)

Rattigan, K. M., Zarou, M.-M., Helgason, G. V. (2023) Metabolism in stem cell driven leukaemia: parallels between haematopoiesis and immunity. Blood, 141, pp. 2553-2565. (doi: 10.1182/blood.2022018258)

Lees, J., Hay, J., Moles, M. W., Michie, A. M. (2023) The discrete roles of individual FOXO transcription factor family members in B-cell malignancies. Frontiers in Immunology, 14, (doi: 10.3389/fimmu.2023.1179101)

Woodley, K., Dillingh, L. S., Giotopoulos, G., Madrigal, P., Rattigan, K. M., Philippe, C., Dembitz, V., Magee, A. M. S., Asby, R., van de Lagemaat, L. N., Mapperley, C., James, S. C., Prehn, J. H. M., Tzelepis, K., Rouault-Pierre, K., Vassiliou, G. S., Kranc, K. R., Helgason, G. V., Huntly, B. J. P., Gallipoli, P. (2023) Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death. Nature Communications, 14, (doi: 10.1038/s41467-023-37652-0)

Fernando, F., Innes, A. J., Claudiani, S., Pryce, A., Hayden, C., Byrne, J., Gallipoli, P., Copland, M., Apperley, J. F., Milojkovic, D. (2023) The outcome of post-transplant asciminib in patients with chronic myeloid leukaemia. Bone Marrow Transplantation, 58, pp. 826-828. (doi: 10.1038/s41409-023-01975-9)

Patterson, S. D., Copland, M. (2023) The bone marrow immune microenvironment in CML: treatment responses, treatment-free remission, and therapeutic vulnerabilities. Current Hematologic Malignancy Reports, 18, pp. 19-32. (doi: 10.1007/s11899-023-00688-6)

Mussai, F., De Santo, C., Cheng, P., Thomas, I. F., Ariti, C., Upton, L., Scarpa, U., Stavrou, V., Sydenham, M., Burnett, A. K., Knapper, S. K., Mehta, P., McMullin, M. F., Copland, M., Russell, N. H., Dennis, M. (2023) A randomised evaluation of low-dose Ara-C plus pegylated recombinant arginase BCT-100 versus low dose Ara-C in older unfit patients with acute myeloid leukaemia: results from the LI-1 trial. British Journal of Haematology, 200, pp. 573-578. (doi: 10.1111/bjh.18560)

Villar, V. H., Allega, M. F., Deshmukh, R., Ackermann, T., Nakasone, M. A., Vande Voorde, J., Drake, T. M., Oetjen, J., Bloom, A., Nixon, C., Müller, M., May, S., Tan, E. H., Vereecke, L., Jans, M., Blancke, G., Murphy, D. J., Huang, D. T., Lewis, D. Y., Bird, T. G., Sansom, O. J., Blyth, K., Sumpton, D., Tardito, S. (2023) Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer. Nature Chemical Biology, 19, pp. 292-300. (doi: 10.1038/s41589-022-01154-9)

Stavrou, V., Fultang, L., Booth, S., De Simone, D., Bartnik, A., Scarpa, U., Gneo, L., Panetti, S., Potluri, S., Almowaled, M., Barlow, J., Jankevics, A., Lloyd, G., Southam, A., Priestman, D. A., Cheng, P., Dunn, W., Platt, F., Endou, H., Craddock, C., Keeshan, K., Mussai, F., De Santo, C. (2023) Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment. Cancer Immunology, Immunotherapy, 72, pp. 543-560. (doi: 10.1007/s00262-022-03268-4)

Leak, S., Horne, G., Copland, M. (2023) Targeting BCR-ABL1-positive leukaemias, a review article. Cambridge Prisms: Precision Medicine, 1, (doi: 10.1017/pcm.2023.9)

Schmidt, T., Dąbrowska, A., Waldron, J. A., Hodge, K., Koulouras, G., Gabrielsen, M., Munro, J., Tack, D. C., Harris, G., McGhee, E., Scott, D., Carlin, L. M., Huang, D., Le Quesne, J., Zanivan, S., Wilczynska, A., Bushell, M. (2023) eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation. Nucleic Acids Research, 51, pp. 1859-1879. (doi: 10.1093/nar/gkad030)

Chen, H. et al. (2023) PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371. Blood Vessels, 141, pp. 244-259. (doi: 10.1182/blood.2022016580)

Mehta, P., Telford, N., Wragg, C., Dillon, R., Freeman, S., Finnegan, D., Hamblin, A., Copland, M., Knapper, S. (2023) A British Society for Haematology good practice paper: Recommendations for laboratory testing of UK patients with acute myeloid leukaemia. British Journal of Haematology, 200, pp. 150-159. (doi: 10.1111/bjh.18516)

Kowalczyk, D., Nakasone, M. A., Smith, B. O., Huang, D. T. (2022) Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function. Life Science Alliance, 5, (doi: 10.26508/lsa.202201472)

Cousins, A., Olivares, O., Markert, E., Manoharan, A., Bubnova, X., Bresolin, S., Degn, M., Li, Z., Silvestri, D., McGregor, G., Tumanov, S., Sumpton, D., Kamphorst, J. J., Michie, A. M., Herzyk, P., Valsecchi, M. G., Yeoh, A. E., Schmiegelow, K., te Kronnie, G., Gottlieb, E., Halsey, C. (2022) Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways. Leukemia, 36, pp. 2903-2907. (doi: 10.1038/s41375-022-01722-x)

Thastrup, M., Duguid, A., Mirian, C., Schmiegelow, K., Halsey, C. (2022) Central nervous system involvement in childhood acute lymphoblastic leukemia: challenges and solutions. Leukemia, 36, pp. 2751-2768. (doi: 10.1038/s41375-022-01714-x)

Hay, J., Tarafdar, A., Holroyd, A. K., Moka, H. A., Dunn, K. M., Alshayeb, A., Lloyd, B. H., Cassels, J., Malik, N., Khan, A. F., Sou, I., Lees, J., Almuhanna, H. N.B., Kalakonda, N., Slupsky, J. R., Michie, A. M. (2022) PKCβ facilitates leukemogenesis in chronic lymphocytic leukaemia by promoting constitutive BCR-mediated signalling. Cancers, 14, (doi: 10.3390/cancers14236006)

Copland, M. (2022) Treatment of blast phase chronic myeloid leukaemia: a rare and challenging entity. British Journal of Haematology, 199, pp. 665-678. (doi: 10.1111/bjh.18370)

Parry, N., Busch, C., Aßmann, V., Cassels, J., Hair, A., Helgason, G. V., Wheadon, H., Copland, M. (2022) BH3 mimetics in combination with nilotinib or ponatinib represent a promising therapeutic strategy in blast phase chronic myeloid leukemia. Cell Death Discovery, 8, (doi: 10.1038/s41420-022-01211-1)

Jamieson, S. A., Pudjihartono, M., Horne, C. R., Viloria, J. S., Dunlop, J. L., McMillan, H. D., Day, R. C., Keeshan, K., Murphy, J. M., Mace, P. D. (2022) Nanobodies identity an activated state of the TRIB2 pseudokinase. Structure, 30, pp. 1518-1529.e5. (doi: 10.1016/j.str.2022.08.006)

Gómez-Castañeda, E., Hopcroft, L. E.M., Rogers, S., Munje, C., Bittencourt-Silvestre, J., Copland, M., Vetrie, D., Holyoake, T., Jørgensen, H. G. (2022) Tyrosine kinase inhibitor independent gene expression signature in CML offers new targets for LSPC eradication therapy. Cancers, 14, (doi: 10.3390/cancers14215253)

Dennis, M., Copland, M., Kaur, H., Kell, J., Nikolousis, E., Mehta, P., Palanicawandar, R., Potter, V., Raj, K., Thomas, I., Wilson, A. (2022) Management of older patients with frailty and acute myeloid leukaemia: a British Society for Haematology good practice paper. British Journal of Haematology, 199, pp. 205-221. (doi: 10.1111/bjh.18369)

Lebecque, B., Bourgne, C., Munje, C., Berger, J., Tassin, T., Cony-Makhoul, P., Guerci, A., Johnson-Ansah, H., Liu, W., Saugues, S., Tchirkov, A., Vetrie, D., Copland, M., Berger, M. G. (2022) The spliceosome: a new therapeutic target in chronic myeloid leukaemia. Cancers, 14, (doi: 10.3390/cancers14194695)

Pal, D., Blair, H., Parker, J., Hockney, S., Beckett, M., Singh, M., Tirtakusuma, R., Nelson, R., McNeill, H., Angel, S. H., Wilson, A., Nizami, S., Nakjang, S., Zhou, P., Schwab, C., Sinclair, P., Russell, L. J., Coxhead, J., Halsey, C., Allan, J. M., Harrison, C. J., Moorman, A. V., Heidenreich, O., Vormoor, J. (2022) hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia. Cell Reports Medicine, 3, (doi: 10.1016/j.xcrm.2022.100717)

Robertson, N. A., Latorre-Crespo, E., Terradas-Terradas, M., Lemos-Portela, J., Purcell, A. C., Livesey, B. J., Hillary, R. F., Murphy, L., Fawkes, A., MacGillivray, L., Copland, M., Marioni, R. E., Marsh, J. A., Harris, S. E., Cox, S. R., Deary, I. J., Schumacher, L. J., Kirschner, K., Chandra, T. (2022) Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects. Nature Medicine, 28, pp. 1439-1446. (doi: 10.1038/s41591-022-01883-3)

Ianniciello, A., Helgason, G. V. (2022) Targeting ULK1 in cancer stem cells: insight from chronic myeloid leukemia. Autophagy, 18, pp. 1734-1736. (doi: 10.1080/15548627.2022.2041152)

Pirillo, C., Birch, F., Tissot, F., Anton, S. G., Haltalli, M., Tini, V., Kong, I., Piot, C., Partridge, B., Pospori, C., Keeshan, K., Santamaria, S., Hawkins, E., Falini, B., Marra, A., Duarte, D., Lee, C. F., Roberts, E., Celso, C. L. (2022) Metalloproteinase inhibition reduces AML growth, prevents stem cell loss and improves chemotherapy effectiveness. Blood Advances, 6, pp. 3126-3141. (doi: 10.1182/bloodadvances.2021004321)

Lal, R., Ritchie, J., Richmond, L., Keeshan, K. (2022) Detecting endogenous TRIB2 protein expression by flow cytometry and western blotting. Academic Press

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