Dr Eline Huethorst

  • Research Associate (Cardiovascular & Metabolic Health)

telephone: 01413304734
email: Eline.Huethorst@glasgow.ac.uk
pronouns: She/her/hers

Room 416, Sir James Black Building, University of Glasgow Campus, G12 8QQ

Import to contacts

ORCID iDhttps://orcid.org/0000-0003-1900-4039

Biography

Eline started her academic career in the Netherlands with an undergraduate in Life Sciences from the University of Groningen, where she gained interest in the field of Regenerative Medicine. She therefore decided to do a postgraduate in Regenerative Medicine at the University of Utrecht. Afterwards, she was awarded a 4-year PHD studentship by the British Heart Foundation and started working at the University of Glasgow to study how small, engineered heart tissues could integrate with the myocardium after implantation.

Eline is now a Research Associate at the University of Glasgow and part of the Glasgow Cardiac Research Centre. Eline is also part of the BHF Centre for Regenerative Medicine, which is a network of universities within the UK that all work together to tackle the big challenges within cardiac regeneration to be able to treat patients that have suffered a heart attack with new cell therapies in the future.

Research interests

Research Theme: Cardiac Diseases

Research groups

Publications

List by: Type | Date

Jump to: 2025 | 2024 | 2022 | 2020 | 2016
Number of items: 10.

2025

Boland, E. et al. (2025) Biomechanical and compositional basement membrane defects due to a Col4a1 mutation affect cardiac morphology and function. Matrix Biology, 141, pp. 82-100. (doi: 10.1016/j.matbio.2025.09.003) (PMID:40946812)

Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Bishop, Martin J., Burton, Francis L., Denning, Chris, Gadegaard, Nikolaj ORCID logoORCID: https://orcid.org/0000-0002-3396-846X, Myles, Rachel C. ORCID logoORCID: https://orcid.org/0000-0003-4670-361X and Smith, Godfrey L. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 (2025) Evidence for intermittent coupling of intramyocardial small, engineered heart tissues acutely implanted into rabbit myocardium. Cardiovascular Research, (doi: 10.1093/cvr/cvaf034) (PMID:40036828) (Early Online Publication)

2024

Shead, Kyle D., Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Burton, Francis, Lang, Ninian ORCID logoORCID: https://orcid.org/0000-0001-8441-6887, Myles, Rachel C. ORCID logoORCID: https://orcid.org/0000-0003-4670-361X and Smith, Godfrey L. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 (2024) Human induced pluripotent stem cell-derived cardiomyocytes for preclinical cardiotoxicity screening in cardio-oncology. JACC: CardioOncology, 6(5), pp. 678-683. (doi: 10.1016/j.jaccao.2024.07.012) (PMID:39479327) (PMCID:PMC11520213)

Astrauskaite, Giedre, Mohanan, Sharika ORCID logoORCID: https://orcid.org/0000-0002-1364-0010, Williamson, Lewis, Boland, Erin, Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Kinegawa, Ryo, Smith, Godfrey ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 and Muellenbroich, Caroline ORCID logoORCID: https://orcid.org/0000-0003-0113-8573 (2024) Remote Focusing for 2-photon Microscopy to Follow Action Potential Propagation Transmurally in Acute Rabbit Cardiac Slices. In: SPIE BiOS 2024, San Francisco, CA, USA, 27 January - 1 February 2024, ISBN 9781510669536 (doi: 10.1117/12.3002956)

Freeman, Michael, Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Boland, Erin, Dunne, Michael, Burton, Francis, Denning, Chris, Myles, Rachel ORCID logoORCID: https://orcid.org/0000-0003-4670-361X and Smith, Godfrey ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 (2024) A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit. American Journal of Physiology: Heart and Circulatory Physiology, 326(3), H735--H751. (doi: 10.1152/ajpheart.00657.2023) (PMID:38180449)

Astrauskaitė, Giedrė, Williamson, Lewis, Mohanan, Sharika ORCID logoORCID: https://orcid.org/0000-0002-1364-0010, Moreno, Steven Milan, Kinegawa, Ryo, Boland, Erin, Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Smith, Godfrey ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 and Müllenbroich, Caroline (2024) Fast Axial Scanning with Remote Focusing for Multiphoton Microscopy of Acute Rabbit Ventricular Slices to Follow Action Potentials Transmurally. In: Conference on Lasers and Electro-Optics (CLEO) 2024: Science and Innovations, Charlotte, North Carolina, USA, 05-10 May 2024, SF2B.1. ISBN 9781957171395 (doi: 10.1364/CLEO_SI.2024.SF2B.1)

2022

Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Mortensen, Peter, Simitev, Radostin D. ORCID logoORCID: https://orcid.org/0000-0002-2207-5789, Gao, Hao ORCID logoORCID: https://orcid.org/0000-0001-6852-9435, Pohjolainen, Lotta, Talman, Virpi, Ruskoaho, Heikki, Burton, Francis L., Gadegaard, Nikolaj ORCID logoORCID: https://orcid.org/0000-0002-3396-846X and Smith, Godfrey L. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 (2022) Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell derived cardiomyocytes. Journal of Physiology, 600(3), pp. 483-507. (doi: 10.1113/JP282228) (PMID:34761809) (PMCID:PMC9299844)

2020

Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Cutiongco, Marie F.A. ORCID logoORCID: https://orcid.org/0000-0002-4873-9643, Campbell, Fraser A., Saeed, Anwer ORCID logoORCID: https://orcid.org/0000-0001-5033-1180, Love, Rachel, Reynolds, Paul M. ORCID logoORCID: https://orcid.org/0000-0001-7614-0008, Dalby, Matthew J. ORCID logoORCID: https://orcid.org/0000-0002-0528-3359 and Gadegaard, Nikolaj ORCID logoORCID: https://orcid.org/0000-0002-3396-846X (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12(2), 025009. (doi: 10.1088/1758-5090/ab5d3f) (PMID:31783378) (PMCID:PMC7655147)

2016

Huethorst, E., Hortigon, M. ORCID logoORCID: https://orcid.org/0000-0001-5531-1779, Zamora-Rodriguez, V., Reynolds, P.M. ORCID logoORCID: https://orcid.org/0000-0001-7614-0008, Burton, F., Smith, G. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 and Gadegaard, N. ORCID logoORCID: https://orcid.org/0000-0002-3396-846X (2016) Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate. ACS Biomaterials Science and Engineering, 2(12), pp. 2231-2239. (doi: 10.1021/acsbiomaterials.6b00426) (PMID:27990488) (PMCID:PMC5155309)

Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Krebber, Merle M., Fledderus, Joost O., Gremmels, Hendrik, Xu, Yan Juan, Pei, Jiayi, Verhaar, Marianne C. and Cheng, Caroline (2016) Lymphatic Vascular Regeneration: The Next Step in Tissue Engineering. Tissue Engineering Part B: Reviews, 22(1), pp. 1-14. (doi: 10.1089/ten.teb.2015.0231) (PMID:26204330)

This list was generated on Thu Oct 30 06:12:13 2025 GMT.
Jump to: Articles | Conference Proceedings
Number of items: 10.

Articles

Boland, E. et al. (2025) Biomechanical and compositional basement membrane defects due to a Col4a1 mutation affect cardiac morphology and function. Matrix Biology, 141, pp. 82-100. (doi: 10.1016/j.matbio.2025.09.003) (PMID:40946812)

Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Bishop, Martin J., Burton, Francis L., Denning, Chris, Gadegaard, Nikolaj ORCID logoORCID: https://orcid.org/0000-0002-3396-846X, Myles, Rachel C. ORCID logoORCID: https://orcid.org/0000-0003-4670-361X and Smith, Godfrey L. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 (2025) Evidence for intermittent coupling of intramyocardial small, engineered heart tissues acutely implanted into rabbit myocardium. Cardiovascular Research, (doi: 10.1093/cvr/cvaf034) (PMID:40036828) (Early Online Publication)

Shead, Kyle D., Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Burton, Francis, Lang, Ninian ORCID logoORCID: https://orcid.org/0000-0001-8441-6887, Myles, Rachel C. ORCID logoORCID: https://orcid.org/0000-0003-4670-361X and Smith, Godfrey L. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 (2024) Human induced pluripotent stem cell-derived cardiomyocytes for preclinical cardiotoxicity screening in cardio-oncology. JACC: CardioOncology, 6(5), pp. 678-683. (doi: 10.1016/j.jaccao.2024.07.012) (PMID:39479327) (PMCID:PMC11520213)

Freeman, Michael, Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Boland, Erin, Dunne, Michael, Burton, Francis, Denning, Chris, Myles, Rachel ORCID logoORCID: https://orcid.org/0000-0003-4670-361X and Smith, Godfrey ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 (2024) A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit. American Journal of Physiology: Heart and Circulatory Physiology, 326(3), H735--H751. (doi: 10.1152/ajpheart.00657.2023) (PMID:38180449)

Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Mortensen, Peter, Simitev, Radostin D. ORCID logoORCID: https://orcid.org/0000-0002-2207-5789, Gao, Hao ORCID logoORCID: https://orcid.org/0000-0001-6852-9435, Pohjolainen, Lotta, Talman, Virpi, Ruskoaho, Heikki, Burton, Francis L., Gadegaard, Nikolaj ORCID logoORCID: https://orcid.org/0000-0002-3396-846X and Smith, Godfrey L. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 (2022) Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell derived cardiomyocytes. Journal of Physiology, 600(3), pp. 483-507. (doi: 10.1113/JP282228) (PMID:34761809) (PMCID:PMC9299844)

Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Cutiongco, Marie F.A. ORCID logoORCID: https://orcid.org/0000-0002-4873-9643, Campbell, Fraser A., Saeed, Anwer ORCID logoORCID: https://orcid.org/0000-0001-5033-1180, Love, Rachel, Reynolds, Paul M. ORCID logoORCID: https://orcid.org/0000-0001-7614-0008, Dalby, Matthew J. ORCID logoORCID: https://orcid.org/0000-0002-0528-3359 and Gadegaard, Nikolaj ORCID logoORCID: https://orcid.org/0000-0002-3396-846X (2020) Customizable, engineered substrates for rapid screening of cellular cues. Biofabrication, 12(2), 025009. (doi: 10.1088/1758-5090/ab5d3f) (PMID:31783378) (PMCID:PMC7655147)

Huethorst, E., Hortigon, M. ORCID logoORCID: https://orcid.org/0000-0001-5531-1779, Zamora-Rodriguez, V., Reynolds, P.M. ORCID logoORCID: https://orcid.org/0000-0001-7614-0008, Burton, F., Smith, G. ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 and Gadegaard, N. ORCID logoORCID: https://orcid.org/0000-0002-3396-846X (2016) Enhanced human-induced pluripotent stem cell derived cardiomyocyte maturation using a dual microgradient substrate. ACS Biomaterials Science and Engineering, 2(12), pp. 2231-2239. (doi: 10.1021/acsbiomaterials.6b00426) (PMID:27990488) (PMCID:PMC5155309)

Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Krebber, Merle M., Fledderus, Joost O., Gremmels, Hendrik, Xu, Yan Juan, Pei, Jiayi, Verhaar, Marianne C. and Cheng, Caroline (2016) Lymphatic Vascular Regeneration: The Next Step in Tissue Engineering. Tissue Engineering Part B: Reviews, 22(1), pp. 1-14. (doi: 10.1089/ten.teb.2015.0231) (PMID:26204330)

Conference Proceedings

Astrauskaite, Giedre, Mohanan, Sharika ORCID logoORCID: https://orcid.org/0000-0002-1364-0010, Williamson, Lewis, Boland, Erin, Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Kinegawa, Ryo, Smith, Godfrey ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 and Muellenbroich, Caroline ORCID logoORCID: https://orcid.org/0000-0003-0113-8573 (2024) Remote Focusing for 2-photon Microscopy to Follow Action Potential Propagation Transmurally in Acute Rabbit Cardiac Slices. In: SPIE BiOS 2024, San Francisco, CA, USA, 27 January - 1 February 2024, ISBN 9781510669536 (doi: 10.1117/12.3002956)

Astrauskaitė, Giedrė, Williamson, Lewis, Mohanan, Sharika ORCID logoORCID: https://orcid.org/0000-0002-1364-0010, Moreno, Steven Milan, Kinegawa, Ryo, Boland, Erin, Huethorst, Eline ORCID logoORCID: https://orcid.org/0000-0003-1900-4039, Smith, Godfrey ORCID logoORCID: https://orcid.org/0000-0003-4821-9741 and Müllenbroich, Caroline (2024) Fast Axial Scanning with Remote Focusing for Multiphoton Microscopy of Acute Rabbit Ventricular Slices to Follow Action Potentials Transmurally. In: Conference on Lasers and Electro-Optics (CLEO) 2024: Science and Innovations, Charlotte, North Carolina, USA, 05-10 May 2024, SF2B.1. ISBN 9781957171395 (doi: 10.1364/CLEO_SI.2024.SF2B.1)

This list was generated on Thu Oct 30 06:12:13 2025 GMT.

Supervision

  • Moreno, Steven Milan
    Optimised Pipeline for Cleaning, Mounting, and Imaging of Mesoscale Leporine Cardiac Tissue Structure
  • Shead, Kyle
    Use of IPSCs as a novel platform to screen for cardiotoxicity in anti-cancer therapies