Dr Antony Workman
- Senior Lecturer (Institute of Cardiovascular & Medical Sciences)
- Associate (School of Medicine, Dentistry & Nursing)
telephone:
01413303451
email:
Antony.Workman@glasgow.ac.uk
Room C342, Institute of Cardiovascular & Medical Sciences, BHF-GCRC 126 University Place, Glasgow G12 8TA
Biography
● BSc Animal Physiology, London University (1988).
● PhD Cardiovascular Pharmacology, De Montfort University, Leicester (1996).
● Postdoctoral Research Fellow, University of Glasgow (1996).
● British Heart Foundation Basic Science Lectureship, University of Glasgow (2001-2005).
● Lecturer, University of Glasgow (2001).
● Postgraduate Certificate in Academic Practice, Glasgow (2004).
● British Heart Foundation Basic Science Lectureship Renewal, University of Glasgow (2006-2011).
● Secured tenured post, University of Glasgow (2006).
● Senior Lecturer, University of Glasgow (2010).
Research interests
Member: Cardiac
Atrial fibrillation (AF) is a disorder of the rhythm of the heart's upper chambers. This disease affects ~1% of the general population, and decreases their life expectancy. My research aims to improve our understanding of the electrophysiological and molecular mechanisms of AF, in the hope that this will lead to more effective treatments.
Research: Human atrial fibrillation
Grants
Grants and Awards listed are those received whilst working with the University of Glasgow.
- Pharmacological and dynamic-clamp narrowing of the calcium current window to inhibit human atrial early after depolarisations and atrial fibrillation.
British Heart Foundation
2021 - 2024
- Cardiac gene therapy with angiotensin-(1-9): dissecting the underlying mechanism for preservation of cardiac function post-myocardial infarction
British Heart Foundation
2017 - 2020
- Adrenoceptor-subtype antagonism profiles with anti-arrhythmic potential in human atrial myocytes
British Heart Foundation
2017 - 2020
- Afib-TrainNet
European Commission
2015 - 2019
- Human atrial action potential alternans and afterdepolarisations: electrophysiological and calcium-cycling mechanisms and effects of myocardial disease
British Heart Foundation
2013 - 2017
- Atrial remodelling of calcium handling and electrophysiology in heart failure.
British Heart Foundation
2009 - 2013
- Atrial myocardial adaptation to prolonged beta-adrenoceptor antagonism in normal and failing hearts
British Heart Foundation
2006 - 2011
- Human atrial cellular calcium handling, arrhythmogenic mechanisms of 5-hydroxytryptamine, and their modulation by atrial fibrillation
British Heart Foundation
2004 - 2007
- Atrial fibrillation-induced ion currents and mRNA levels in the human atrium
British Heart Foundation
2001 - 2006
Professional activities & recognition
Selected international presentations
- 2019: AFib-TrainNet -“Human atrial cellular electrophysiology and dynamic-clamp technique” (Copenhagen, Denmark)
- 2017: “Connecting human heart cells with mathematical models of ion currents in-vitro” (Leeds, UK)
- 2016: AFib-TrainNet -“Dynamic-clamping human atrial cells: contribution of ISK to action potential changes in AF” (Copenhagen, Denmark)
- 2014: “Connecting human heart cells with mathematical models of ion currents in-vitro” (Manchester, UK)
- 2013: Exercise in Medicine -“Basic mechanisms of atrial fibrillation: insights from human atrial cells and failing rabbit hearts” (Trondheim, Norway)
- 2013: Functional Imaging and Modeling of the Heart -“Atrial fibrillation: ionic mechanisms of self-perpetuation and pharmacological prevention” (London, UK)
- 2012: Heart Rhythm UK - "Atrial cellular remodelling by heart disease, arrhythmias and drugs" (Birmingham, UK)
- 2012: Physiological Society - "Mechanisms of human atrial fibrillation: insights from cellular electrophysiology studies" (Manchester, UK)
- 2010: American College of Cardiology - "Remodelling of the action potential in atrial fibrillation" (Atlanta, GA, USA)
- 2010: California Heart Rhythm Symposium - "Cellular basis of atrial fibrillation" (Santa Monica, CA, USA)
- 2009: Recent Developments in Interventional Cardiology, associated with Br J Hosp Med - "Causes and mechanisms of atrial fibrillation and ventricular arrhythmias" (London, UK)
- 2009: American College of Cardiology - "Electrical Remodeling in Atrial Fibrillation" (Orlando, FL, USA)
- 2009: British Pharmacological Society & German Societies for Pharmacology and Clinical Pharmacology - "Cardiac adrenergic control and atrial fibrillation" (Dresden, Germany)
- 2007: California Heart Rhythm Symposium - "Cellular bases for human atrial fibrillation" (Santa Monica, CA, USA)
- 2005: Europace - "Remodelling the potassium sodium pump during atrial fibrillation" (Prague, Czech Republic)
- 2003: Vascular Biology Working Group - "Chronic beta-adrenoceptor blockade and human atrial cell electrophysiology: Evidence of pharmacological remodeling" (Vienna, Austria)