Professor Sara Rossana Zanivan

  • Professor (Beatson Institute for Cancer Research)

Publications

List by: Type | Date

Jump to: 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2011 | 2008 | 2007 | 2005 | 2003
Number of items: 37.

2019

Ferraro, D., Patella, F., Zanivan, S. R. , Donato, C., Aceto, N., Giannotta, M., Dejana, E., Diepenbruck, M., Christofori, G. and Buess, M. (2019) Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells. BMC Cancer, 19, 312. (doi:10.1186/s12885-019-5521-8) (PMID:30947697) (PMCID:PMC6449935)

Kugeratski, F. G. et al. (2019) Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling. Science Signaling, 12(567), eaan8247. (doi:10.1126/scisignal.aan8247) (PMID:30723174)

Unbekandt, M., Lilla, S., Zanivan, S. R. and Olson, M. F. (2019) The CDC42 effector protein MRCKß autophosphorylates on Threonine 1108. Small GTPases, (doi:10.1080/21541248.2018.1564472) (PMID:30667325) (Early Online Publication)

2018

Novo, D. et al. (2018) Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. Nature Communications, 9, 5069. (doi:10.1038/s41467-018-07339-y) (PMID:30498210) (PMCID:PMC6265295)

Fort, L. et al. (2018) Fam49/CYRI interacts with Rac1 and locally suppresses protrusions. Nature Cell Biology, 20(10), pp. 1159-1171. (doi:10.1038/s41556-018-0198-9) (PMID:30250061)

Dandoulaki, M., Petsalaki, E., Sumpton, D., Zanivan, S. and Zachos, G. (2018) Src activation by Chk1 promotes actin patch formation and prevents chromatin bridge breakage in cytokinesis. Journal of Cell Biology, 217(9), pp. 3071-3089. (doi:10.1083/jcb.201802102) (PMID:29954829)

Port, J. et al. (2018) Colorectal tumors require NUAK1 for protection from oxidative stress. Cancer Discovery, 8(5), pp. 632-647. (doi:10.1158/2159-8290.CD-17-0533) (PMID:29500295)

van der Reest, J., Lilla, S., Zheng, L., Zanivan, S. and Gottlieb, E. (2018) Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress. Nature Communications, 9, 1581. (doi:10.1038/s41467-018-04003-3) (PMID:29679077) (PMCID:PMC5910380)

Santi, A., Kugeratski, F. G. and Zanivan, S. (2018) Cancer associated fibroblasts: the architects of stroma remodelling. Proteomics, 18(5-6), 1700167. (doi:10.1002/pmic.201700167) (PMID:29280568)

Kugeratski, F. G., Batista, M., Lima, C. V. d. P., Neilson, L. J., da Cunha, E. S., de Godoy, L. M., Zanivan, S. , Krieger, M. A. and Marchini, F. K. (2018) Mitogen-activated protein kinase kinase 5 regulates proliferation and biosynthetic processes in procyclic forms of Trypanosoma brucei. Journal of Proteome Research, 17(1), pp. 108-118. (doi:10.1021/acs.jproteome.7b00415) (PMID:29043805)

2017

van den Eshof, B. L., Hoogendijk, A. J., Simpson, P. J., van Alphen, F. P.J., Zanivan, S. , Mertens, K., Meijer, A. B. and van den Biggelaar, M. (2017) Paradigm of biased PAR1 (protease-activated receptor-1) activation and inhibition in endothelial cells dissected by phosphoproteomics. Arteriosclerosis, Thrombosis, and Vascular Biology, 37(10), pp. 1891-1902. (doi:10.1161/ATVBAHA.117.309926) (PMID:28818855)

Reid, S. E. et al. (2017) Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium. EMBO Journal, 36(16), pp. 2373-2389. (doi:10.15252/embj.201694912) (PMID:28694244) (PMCID:PMC5556271)

Hernandez-Fernaud, J. R. et al. (2017) Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nature Communications, 8, 14206. (doi:10.1038/ncomms14206) (PMID:28198360) (PMCID:PMC5316871)

Diaz-Vera, J., Palmer, S., Hernandez-Fernaud, J. R., Dornier, E., Mitchell, L. E., MacPherson, I. , Edwards, J. , Zanivan, S. and Norman, J. C. (2017) A proteomic approach to identify endosomal cargoes controlling cancer invasiveness. Journal of Cell Science, 130(4), pp. 697-711. (doi:10.1242/jcs.190835) (PMID:28062852)

Norman, J. and Zanivan, S. (2017) Chloride intracellular channel 3: a secreted pro-invasive oxidoreductase. Cell Cycle, 16(21), pp. 1993-1994. (doi:10.1080/15384101.2017.1377031) (PMID:28933594)

Reid, S. E. and Zanivan, S. (2017) Tumor stiffness extends its grip on the metastatic microenvironment. Molecular and Cellular Oncology, 4(6), e1372866. (doi:10.1080/23723556.2017.1372866)

2016

Patella, F., Neilson, L., Athineos, D., Erami Rud Majani, Z., Anderson, K. I., Blyth, K. , Ryan, K. and Zanivan, S. R. (2016) In-depth proteomics identifies a role for autophagy in controlling reactive oxygen species mediated endothelial permeability. Journal of Proteome Research, 15(7), pp. 2187-2197. (doi:10.1021/acs.jproteome.6b00166) (PMID:27246970)

Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi:10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)

2015

Deschoemaeker, S. et al. (2015) PHD1 regulates p53-mediated colorectal cancer chemoresistance. EMBO Molecular Medicine, 7(10), pp. 1350-65. (doi:10.15252/emmm.201505492) (PMID:26290450) (PMCID:PMC4604688)

Kuchnio, A. et al. (2015) The cancer cell oxygen sensor PHD2 promotes metastasis via activation of cancer-associated fibroblasts. Cell Reports, 12(6), pp. 992-1005. (doi:10.1016/j.celrep.2015.07.010) (PMID:26235614)

Patella, F. et al. (2015) Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability. Molecular and Cellular Proteomics, 14(3), pp. 621-634. (doi:10.1074/mcp.M114.045575) (PMID:25573745) (PMCID:PMC4349982)

2014

Guo, Z., Neilson, L. J., Zhong, H., Murray, P. S., Zanivan, S. R. and Zaidel-Bar, R. (2014) E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Science Signaling, 7(354), rs7. (doi:10.1126/scisignal.2005473)

van den Biggelaar, M., Hernández-Fernaud, J. R., van den Eshof, B. L., Neilson, L. J., Meijer, A. B., Mertens, K. and Zanivan, S. (2014) Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells. Blood, 123(12), e22-e36. (doi:10.1182/blood-2013-12-546036)

Reid, S., Hernandez-Fernaud, J. R. and Zanivan, S. (2014) In vivo quantitative proteomics for the study of oncometabolism. Methods in Enzymology, 543, pp. 235-259. (doi:10.1016/B978-0-12-801329-8.00012-X)

2013

Zanivan, S. , Maione, F., Hein, M. Y., Hernandez-Fernaud, J. R., Ostasiewicz, P., Giraudo, E. and Mann, M. (2013) SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers. Molecular and Cellular Proteomics, 12(12), pp. 3599-3611. (doi:10.1074/mcp.M113.031344)

Hernandez, J.R., Reid, S.E., Neilson, L.J. and Zanivan, S. (2013) Quantitative mass spectrometry-based proteomics in angiogenesis. Proteomics Clinical Applications, 7(7-8), pp. 464-476. (doi:10.1002/prca.201200055)

Muller, P.A.J. et al. (2013) Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion. Oncogene, 32(10), pp. 1252-1265. (doi:10.1038/onc.2012.148)

Zanivan, S. et al. (2013) In Vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis. Cell Reports, 3(2), pp. 552-566. (doi:10.1016/j.celrep.2013.01.003)

Neuhauser, N., Nagaraj, N., McHardy, P., Zanivan, S. , Scheltema, R., Cox, J. and Mann, M. (2013) High performance computational analysis of large-scale proteome data sets to assess incremental contribution to coverage of the human genome. Journal of Proteome Research, 12(6), pp. 2858-2868. (doi:10.1021/pr400181q)

Schiller, H.B. et al. (2013) β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments. Nature Cell Biology, 15(6), pp. 625-636. (doi:10.1038/ncb2747)

2011

Scholten, A., Mohammed, S., Low, T. Y., Zanivan, S. , van Veen, T. A.B., Delanghe, B. and Heck, A. J.R. (2011) In-depth quantitative cardiac proteomics combining electron transfer dissociation and the metalloendopeptidase Lys-N with the SILAC mouse. Molecular and Cellular Proteomics, 10(10), O111.00847. (doi:10.1074/mcp.O111.008474) (PMID:21705516) (PMCID:PMC3205878)

Meves, A., Geiger, T., Zanivan, S. , DiGiovanni, J., Mann, M. and Fassler, R. (2011) β1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation. Proceedings of the National Academy of Sciences of the United States of America, 108(37), pp. 15213-15218. (doi:10.1073/pnas.1105689108)

2008

Zanivan, S. , Gnad, F., Wickstrom, S. A., Geiger, T., Macek, B., Cox, J., Fassler, R. and Mann, M. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. Journal of Proteome Research, 7(12), pp. 5314-5326. (doi:10.1021/pr800599n) (PMID:19367708)

Krüger, M., Moser, M., Ussar, S., Thievessen, I., Luber, C.A., Forner, F., Schmidt, S., Zanivan, S. , Fässler, R. and Mann, M. (2008) Silac mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. Cell, 134(2), pp. 353-364. (doi:10.1016/j.cell.2008.05.033)

2007

Zanivan, S. , Cascone, I., Peyron, C., Molineris, I., Marchio, S., Caselle, M. and Bussolino, F. (2007) A new computational approach to analyze human protein complexes and predict novel protein interactions. Genome Biology, 8, R256. (doi:10.1186/gb-2007-8-12-r256) (PMID:18053208) (PMCID:PMC2246258)

2005

Parsons-Wingerter, P. et al. (2005) Uniform overexpression and rapid accessibility of alpha5beta1 integrin on blood vessels in tumors. American Journal of Pathology, 167(1), pp. 193-211. (doi:10.1016/s0002-9440(10)62965-3) (PMID:15972964) (PMCID:PMC1603436)

2003

Serini, G. et al. (2003) Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature, 424, pp. 391-397. (doi:10.1038/nature01784) (PMID:12879061)

This list was generated on Tue Dec 10 11:22:33 2019 GMT.
Jump to: Articles
Number of items: 37.

Articles

Ferraro, D., Patella, F., Zanivan, S. R. , Donato, C., Aceto, N., Giannotta, M., Dejana, E., Diepenbruck, M., Christofori, G. and Buess, M. (2019) Endothelial cell-derived nidogen-1 inhibits migration of SK-BR-3 breast cancer cells. BMC Cancer, 19, 312. (doi:10.1186/s12885-019-5521-8) (PMID:30947697) (PMCID:PMC6449935)

Kugeratski, F. G. et al. (2019) Hypoxic cancer–associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling. Science Signaling, 12(567), eaan8247. (doi:10.1126/scisignal.aan8247) (PMID:30723174)

Unbekandt, M., Lilla, S., Zanivan, S. R. and Olson, M. F. (2019) The CDC42 effector protein MRCKß autophosphorylates on Threonine 1108. Small GTPases, (doi:10.1080/21541248.2018.1564472) (PMID:30667325) (Early Online Publication)

Novo, D. et al. (2018) Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. Nature Communications, 9, 5069. (doi:10.1038/s41467-018-07339-y) (PMID:30498210) (PMCID:PMC6265295)

Fort, L. et al. (2018) Fam49/CYRI interacts with Rac1 and locally suppresses protrusions. Nature Cell Biology, 20(10), pp. 1159-1171. (doi:10.1038/s41556-018-0198-9) (PMID:30250061)

Dandoulaki, M., Petsalaki, E., Sumpton, D., Zanivan, S. and Zachos, G. (2018) Src activation by Chk1 promotes actin patch formation and prevents chromatin bridge breakage in cytokinesis. Journal of Cell Biology, 217(9), pp. 3071-3089. (doi:10.1083/jcb.201802102) (PMID:29954829)

Port, J. et al. (2018) Colorectal tumors require NUAK1 for protection from oxidative stress. Cancer Discovery, 8(5), pp. 632-647. (doi:10.1158/2159-8290.CD-17-0533) (PMID:29500295)

van der Reest, J., Lilla, S., Zheng, L., Zanivan, S. and Gottlieb, E. (2018) Proteome-wide analysis of cysteine oxidation reveals metabolic sensitivity to redox stress. Nature Communications, 9, 1581. (doi:10.1038/s41467-018-04003-3) (PMID:29679077) (PMCID:PMC5910380)

Santi, A., Kugeratski, F. G. and Zanivan, S. (2018) Cancer associated fibroblasts: the architects of stroma remodelling. Proteomics, 18(5-6), 1700167. (doi:10.1002/pmic.201700167) (PMID:29280568)

Kugeratski, F. G., Batista, M., Lima, C. V. d. P., Neilson, L. J., da Cunha, E. S., de Godoy, L. M., Zanivan, S. , Krieger, M. A. and Marchini, F. K. (2018) Mitogen-activated protein kinase kinase 5 regulates proliferation and biosynthetic processes in procyclic forms of Trypanosoma brucei. Journal of Proteome Research, 17(1), pp. 108-118. (doi:10.1021/acs.jproteome.7b00415) (PMID:29043805)

van den Eshof, B. L., Hoogendijk, A. J., Simpson, P. J., van Alphen, F. P.J., Zanivan, S. , Mertens, K., Meijer, A. B. and van den Biggelaar, M. (2017) Paradigm of biased PAR1 (protease-activated receptor-1) activation and inhibition in endothelial cells dissected by phosphoproteomics. Arteriosclerosis, Thrombosis, and Vascular Biology, 37(10), pp. 1891-1902. (doi:10.1161/ATVBAHA.117.309926) (PMID:28818855)

Reid, S. E. et al. (2017) Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium. EMBO Journal, 36(16), pp. 2373-2389. (doi:10.15252/embj.201694912) (PMID:28694244) (PMCID:PMC5556271)

Hernandez-Fernaud, J. R. et al. (2017) Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity. Nature Communications, 8, 14206. (doi:10.1038/ncomms14206) (PMID:28198360) (PMCID:PMC5316871)

Diaz-Vera, J., Palmer, S., Hernandez-Fernaud, J. R., Dornier, E., Mitchell, L. E., MacPherson, I. , Edwards, J. , Zanivan, S. and Norman, J. C. (2017) A proteomic approach to identify endosomal cargoes controlling cancer invasiveness. Journal of Cell Science, 130(4), pp. 697-711. (doi:10.1242/jcs.190835) (PMID:28062852)

Norman, J. and Zanivan, S. (2017) Chloride intracellular channel 3: a secreted pro-invasive oxidoreductase. Cell Cycle, 16(21), pp. 1993-1994. (doi:10.1080/15384101.2017.1377031) (PMID:28933594)

Reid, S. E. and Zanivan, S. (2017) Tumor stiffness extends its grip on the metastatic microenvironment. Molecular and Cellular Oncology, 4(6), e1372866. (doi:10.1080/23723556.2017.1372866)

Patella, F., Neilson, L., Athineos, D., Erami Rud Majani, Z., Anderson, K. I., Blyth, K. , Ryan, K. and Zanivan, S. R. (2016) In-depth proteomics identifies a role for autophagy in controlling reactive oxygen species mediated endothelial permeability. Journal of Proteome Research, 15(7), pp. 2187-2197. (doi:10.1021/acs.jproteome.6b00166) (PMID:27246970)

Clarke, C. J. et al. (2016) The initiator methionine tRNA drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis. Current Biology, 26(6), pp. 755-765. (doi:10.1016/j.cub.2016.01.045) (PMID:26948875) (PMCID:PMC4819511)

Deschoemaeker, S. et al. (2015) PHD1 regulates p53-mediated colorectal cancer chemoresistance. EMBO Molecular Medicine, 7(10), pp. 1350-65. (doi:10.15252/emmm.201505492) (PMID:26290450) (PMCID:PMC4604688)

Kuchnio, A. et al. (2015) The cancer cell oxygen sensor PHD2 promotes metastasis via activation of cancer-associated fibroblasts. Cell Reports, 12(6), pp. 992-1005. (doi:10.1016/j.celrep.2015.07.010) (PMID:26235614)

Patella, F. et al. (2015) Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability. Molecular and Cellular Proteomics, 14(3), pp. 621-634. (doi:10.1074/mcp.M114.045575) (PMID:25573745) (PMCID:PMC4349982)

Guo, Z., Neilson, L. J., Zhong, H., Murray, P. S., Zanivan, S. R. and Zaidel-Bar, R. (2014) E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Science Signaling, 7(354), rs7. (doi:10.1126/scisignal.2005473)

van den Biggelaar, M., Hernández-Fernaud, J. R., van den Eshof, B. L., Neilson, L. J., Meijer, A. B., Mertens, K. and Zanivan, S. (2014) Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells. Blood, 123(12), e22-e36. (doi:10.1182/blood-2013-12-546036)

Reid, S., Hernandez-Fernaud, J. R. and Zanivan, S. (2014) In vivo quantitative proteomics for the study of oncometabolism. Methods in Enzymology, 543, pp. 235-259. (doi:10.1016/B978-0-12-801329-8.00012-X)

Zanivan, S. , Maione, F., Hein, M. Y., Hernandez-Fernaud, J. R., Ostasiewicz, P., Giraudo, E. and Mann, M. (2013) SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers. Molecular and Cellular Proteomics, 12(12), pp. 3599-3611. (doi:10.1074/mcp.M113.031344)

Hernandez, J.R., Reid, S.E., Neilson, L.J. and Zanivan, S. (2013) Quantitative mass spectrometry-based proteomics in angiogenesis. Proteomics Clinical Applications, 7(7-8), pp. 464-476. (doi:10.1002/prca.201200055)

Muller, P.A.J. et al. (2013) Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion. Oncogene, 32(10), pp. 1252-1265. (doi:10.1038/onc.2012.148)

Zanivan, S. et al. (2013) In Vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis. Cell Reports, 3(2), pp. 552-566. (doi:10.1016/j.celrep.2013.01.003)

Neuhauser, N., Nagaraj, N., McHardy, P., Zanivan, S. , Scheltema, R., Cox, J. and Mann, M. (2013) High performance computational analysis of large-scale proteome data sets to assess incremental contribution to coverage of the human genome. Journal of Proteome Research, 12(6), pp. 2858-2868. (doi:10.1021/pr400181q)

Schiller, H.B. et al. (2013) β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments. Nature Cell Biology, 15(6), pp. 625-636. (doi:10.1038/ncb2747)

Scholten, A., Mohammed, S., Low, T. Y., Zanivan, S. , van Veen, T. A.B., Delanghe, B. and Heck, A. J.R. (2011) In-depth quantitative cardiac proteomics combining electron transfer dissociation and the metalloendopeptidase Lys-N with the SILAC mouse. Molecular and Cellular Proteomics, 10(10), O111.00847. (doi:10.1074/mcp.O111.008474) (PMID:21705516) (PMCID:PMC3205878)

Meves, A., Geiger, T., Zanivan, S. , DiGiovanni, J., Mann, M. and Fassler, R. (2011) β1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation. Proceedings of the National Academy of Sciences of the United States of America, 108(37), pp. 15213-15218. (doi:10.1073/pnas.1105689108)

Zanivan, S. , Gnad, F., Wickstrom, S. A., Geiger, T., Macek, B., Cox, J., Fassler, R. and Mann, M. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. Journal of Proteome Research, 7(12), pp. 5314-5326. (doi:10.1021/pr800599n) (PMID:19367708)

Krüger, M., Moser, M., Ussar, S., Thievessen, I., Luber, C.A., Forner, F., Schmidt, S., Zanivan, S. , Fässler, R. and Mann, M. (2008) Silac mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. Cell, 134(2), pp. 353-364. (doi:10.1016/j.cell.2008.05.033)

Zanivan, S. , Cascone, I., Peyron, C., Molineris, I., Marchio, S., Caselle, M. and Bussolino, F. (2007) A new computational approach to analyze human protein complexes and predict novel protein interactions. Genome Biology, 8, R256. (doi:10.1186/gb-2007-8-12-r256) (PMID:18053208) (PMCID:PMC2246258)

Parsons-Wingerter, P. et al. (2005) Uniform overexpression and rapid accessibility of alpha5beta1 integrin on blood vessels in tumors. American Journal of Pathology, 167(1), pp. 193-211. (doi:10.1016/s0002-9440(10)62965-3) (PMID:15972964) (PMCID:PMC1603436)

Serini, G. et al. (2003) Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function. Nature, 424, pp. 391-397. (doi:10.1038/nature01784) (PMID:12879061)

This list was generated on Tue Dec 10 11:22:33 2019 GMT.

Research datasets

Jump to: 2018 | 2015
Number of items: 2.

2018

Monteverde, T., Neilson, L., Zanivan, S. R. and Murphy, D. (2018) Colorectal tumors require NUAK1 for protection from oxidative stress. [Data Collection]

2015

Patella, F., Schug, Z. T., Persi, E., Neilson, L., Erami, Z., Avanzato, D., Maione, F., Hernandez-Fernaud, J. R., Mackay, G., Zheng, L., Reid, S., Frezza, C., Giraudo, E., Pla, A. F., Anderson, K., Ruppin, E., Gottlieb, E. and Zanivan, S. R. (2015) Proteomics-Based Metabolic Modeling Reveals That Fatty Acid Oxidation (FAO) Controls Endothelial Cell (EC) Permeability. [Data Collection]

This list was generated on Tue Dec 10 11:22:36 2019 GMT.